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Non-small cell lung cancer (NSCLC) is a frequent tumor entity with high mortality. Although several newly discovered chromosomal translocations and mutations opened new horizons for targeted therapy, literature still lacks large series of NSCLC with chromosomal abberations and their correlations with histological and clinical features. We present a case of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK) translocation positive adenocarcinoma of the lung with an unusual metastatic pattern in a 29-year-old young woman. Conclusion: Young adult non-smoker female patients with an unexplained pleural effusion and signs of metastatic disease should alert the physicians straight away for all types of malignancies including lung cancer. Any skin lesions should be evaluated carefully, biopsies should be done to exclude metastasis in urgency. On the other hand, an uncommon clinical presentation of a lung cancer requires corresponding molecular testing rapidly in order to offer the best treatment option.

Objective: Carbon monoxide (CO) poisoning is a condition which oxygen transport is reduced and presentation is impaired. Red cell distribution width (RDW) is associated with many diseases. Although there are many studies on RDW in the literature, there are very few studies evaluating the relationship between CO poisoning and RDW. The aim of our study is to investigate whether relationship between CO poisoning and RDW. Methods: Patients who applied to the emergency service, CO poisoning was diagnosed, their age 18 years and over, their blood gas measurements showed a carboxyhemoglobin (COHb) level of ≥5%, were taken in this retrospective study. It was recorded that research participants' age, sex, COHb levels in blood gases, hemogram, consultation due to CO poisoning and effects, whether taken hyperbaric oxygen (HBO) and its outcomes. Whether there was a change that could be attributed to CO poisoning at the RDW levels was investigated. Results: Fifty-nine cases were included in the study. The mean RDW of the study group (13.61+-1.12) was higher than that of the control group (12.99+-0.59) (p

Urban Air Mobility (UAM) is a new concept offered for solving urban transportation system problems, contributing to reducing traffic congestion, atmospheric pollution and mobility around metropolitan areas which is progressively an evolved aviation market. Facing the evolved dynamics in the airspace and on the ground, developed new technologies are able to withstand against destroy transportation infrastructures of the big cities, making it necessary to develop UAM services in the megapolises and regional transportation sector. Based on new technologies and modern business approaches, applying the next generation aviation infrastructure makes it capable of setting up a novel air traffic within the urban environment. This case study aims to explore the urban air transport advantages, particularly adoption of UAM, which might be an alternative next generation air transportation system. Referring to the collected operational data and design performances of the UAM, in this paper, we will try to describe a multi approach studying differences between traditional aviation transportation and UAM operation. The first step of the study consists of defining an airspace classification for UAM mission and use of applicable requirements for air navigation service providers and second part of the study describes performing UAM infrastructure and design of vertiports necessary for vertical take-off and landing (VTOL) vehicles. Detailed design specification is not included in this study but limited characteristics are indicated according to the VTOL manufacturer that are obtained from the test results. As far as VTOL vehicles have not started their mission yet, the UAM operators are at the stage of development to set up their future operation. The expected trend provides justifiable assumptions of the necessity of establishing the new transportation ramification within the aviation industry, upon transforming existing business activities and regulations.