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248 results on '"Polat, Fatih"'

3. Prognostic significance of MRI-detected extramural venous invasion according to grade and response to neo-adjuvant treatment in locally advanced rectal cancer A national cohort study after radiologic training and reassessment

Author

Aalbers, Arend G.J., van Aalten, Susanna M., Amelung, Femke J., Ankersmit, Marjolein, Antonisse, Imogeen E., Ashruf, Jesse F., Aukema, Tjeerd S., Avenarius, Henk, Bahadoer, Renu R., Bakers, Frans C.H., Bakker, Ilsalien S., Bangert, Fleur, Barendse, Renée M., Beekhuis, Heleen M.D., Beets, Geerard L., Bemelman, Willem A., Berbée, Maaike, de Bie, Shira H., Bisschops, Robert H.C., Blok, Robin D., van Bockel, Liselotte W., Boer, Anniek H., den Boer, Frank C., Boerma, Evert-Jan G., Boogerd, Leonora S.F., Borstlap, Jaap, Borstlap, Wernard A.A., Bouwman, Johanna E., Braak, Sicco J., Braat, Manon N.G.J.A., Bradshaw, Jennifer, Brandsma, Amarins T.A., van Breest Smallenburg, Vivian, van den Broek, Wim T., van der Burg, Sjirk W., Burger, Jacobus W.A., Burghgraef, Thijs A., ten Cate, David W.G., Ceha, Heleen M., Cnossen, Jeltsje S., Coebergh van den Braak, Robert R.J., Consten, Esther C.J., Corver, Maaike, Crolla, Rogier M.P.H., Curutchet, Sam, Daniëls-Gooszen, Alette W., Davids, Paul H.P., Dekker, Emmelie N., Dekker, Jan Willem T., Demirkiran, Ahmet, Derksen, Tyche, Diederik, Arjen L., Dinaux, Anne M., Dogan, Kemal, van Dop, Ilse M., Droogh-de Greve, Kitty E., Duijsens, Hanneke M.H., Dunker, Michalda S., Duyck, Johan, van Duyn, Eino B., van Egdom, Laurentine S.E., Eijlers, Bram, El-Massoudi, Youssef, van Elderen, Saskia, Emmen, Anouk M.L.H., Engelbrecht, Marc, van Erp, Anne C., van Essen, Jeroen A., Fabry, Hans F.J., Fassaert, Thomas, Feitsma, Eline A., Feshtali, Shirin S., Frietman, Bas, Furnée, Edgar J.B., van Geel, Anne M., Geijsen, Elisabeth D., van Geloven, Anna A.W., Gerhards, Michael F., Gielkens, Hugo, van Gils, Renza A.H., Goense, Lucas, Govaert, Marc J.P.M., van Grevenstein, Wilhelmina M.U., Joline de Groof, E., de Groot, Irene, de Haas, Robbert J., Hakkenbrak, Nadia A.G., den Hartogh, Mariska D., Heesink, Vera, Heikens, Joost T., Hendriksen, Ellen M., van den Hoek, Sjoerd, van der Hoeven, Erik J.R.J., Hoff, Christiaan, Hogewoning, Anna, Hogewoning, Cornelis R.C., Hoogendoorn, Stefan, van Hoorn, Francois, van der Hul, René L., van Hulst, Rieke, Imani, Farshad, Inberg, Bas, Intven, Martijn P.W., Janssen, Pedro, de Jong, Chris E.J., Jonkers, Jacoline, Jou-Valencia, Daniela, Keizers, Bas, Ketelaers, Stijn H.J., Knöps, Eva, van Koeverden, Sebastiaan, Kok, Sylvia, Kolderman, Stephanie E.M., de Korte, Fleur I., Kortekaas, Robert T.J., Korving, Julie C., Koster, Ingrid M., Krdzalic, Jasenko, Krielen, Pepijn, Kroese, Leonard F., Krul, Eveline J.T., Lahuis, Derk H.H., Lamme, Bas, van Landeghem, An A.G., Leijtens, Jeroen W.A., Leseman-Hoogenboom, Mathilde M., de Lijster, Manou S., Marsman, Martijn S., Martens, MilouH., Masselink, Ilse, van der Meij, Wout, Meijnen, Philip, Melenhorst, Jarno, de Mey, Dietrich J.L., Moelker-Galuzina, Julia, Morsink, Linda, Mulder, Erik J., Muller, Karin, Musters, Gijsbert D., Neijenhuis, Peter A., de Nes, Lindsey C.F., Nielen, M., van den Nieuwboer, Jan B.J., Nieuwenhuis, Jonanne F., Nonner, Joost, Noordman, Bo J., Nordkamp, Stefi, Olthof, Pim B., Oosterling, Steven J., Ootes, Daan, Oppedijk, Vera, Ott, Pieter, Paulusma, Ida, Peeters, Koen C.M.J., Pereboom, Ilona T.A., Peringa, Jan, Pironet, Zoë, Plate, Joost D.J., Polat, Fatih, Poodt, Ingrid G.M., Posma, Lisanne A.E., Prette, Jeroen F., Pultrum, Bareld B., Qaderi, Seyed M., van Rees, Jan M., Renger, Rutger-Jan, Rombouts, Anouk J.M., Roosen, Lodewijk J., Roskott-ten Brinke, Ellen A., Rothbarth, Joost, Rouw, Dennis B., Rozema, Tom, Rütten, Heidi, Rutten, Harm J.T., van der Sande, Marit E., Schaafsma, Boudewijn E., Schasfoort, Renske A., Scheurkogel, Merel M., Schouten van der Velden, Arjan P., Schreurs, Wilhelmina H., Schuivens, Puck M.E., Sietses, Colin, Simons, Petra C.G., Slob, Marjan J., Slooter, Gerrit D., van der Sluis, Martsje, Smalbroek, Bo P., Smits, Anke B., Spillenaar-Bilgen, Ernst J., Spruit, Patty H., Stam, Tanja C., Stoker, Jaap, Talsma, Aaldert K., Temmink, Sofieke J.D., The, G.Y. Mireille, Tielbeek, Jeroen A.W., van Tilborg, Aukje A.J.M., van Tilborg, Fiek, van Trier, Dorothée, Tuynman, Jurriaan B., van der Valk, Maxime J.M., Vanhooymissen, Inge J.S., Vasbinder, G. Boudewijn C., Veeken, Cornelis J., Velema, Laura A., van de Ven, Anthony W.H., Verdaasdonk, Emiel G.G., Verduin, Wouter M., Verhagen, Tim, Verheijen, Paul M., Vermaas, Maarten, Verrijssen, An-Sofie E., Verschuur, Anna V.D., Schaik, Harmke Verwoerd-van, Vliegen, Roy F.A., Voets, Sophie, Vogelaar, F. Jeroen, Vogelij, Clementine L.A., Vos-Westerman, Johanna, de Vries, Marianne, Vroemen, Joy C., van Vugt, Bas S.T., Wegdam, Johannes A., van Wely, Bob J., Westerterp, Marinke, van Westerveld, Paul P., van Westreenen, Henderik L., Wijma, Allard G., de Wilt, Johannes H.W., de Wit, Bart W.K., Wit, Fennie, Woensdregt, Karlijn, van Woerden, Victor, van der Wolf, Floor S.W., van der Wolk, Sander, Wybenga, Johannes M., van der Zaag, Edwin S., Zamaray, Bobby, Zandvoort, Herman J.A., van der Zee, Dennis, Zeilstra, Annette P., Zheng, Kang J., Zimmerman, David D.E., Zorgdrager, Marcel, Geffen, Eline G.M. van, Nederend, Joost, Sluckin, Tania C., Hazen, Sanne-Marije J.A., Horsthuis, Karin, Beets-Tan, Regina G.H., Marijnen, Corrie A.M., Tanis, Pieter J., and Kusters, Miranda

Published
2024
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4. Persistent and new-onset symptoms after cholecystectomy in patients with uncomplicated symptomatic cholecystolithiasis: A post hoc analysis of 2 prospective clinical trials

Author

Buyne, Otmar, Donkervoort, Sandra C., Heisterkamp, Joos, ’t Hof, Klaas in, Jansen, Jan, Nieuwenhuijs, Vincent B., Schaap, Henk M., Steenvoorde, Pascal, Boerma, Djamila, Hazebroek, Eric J., Hirsch, David, Heikens, Joost T., Konsten, Joop, Polat, Fatih, van der Bilt, Jarmila D.W., Schreinemakers, Jennifer M.J., Wiering, Bastiaan, Stockmann, Hein B.A.C., Boermeester, Marja, Thunnissen, Floris M., Baars, Cléo, Arts, Rianne, Latenstein, Carmen S.S., Drenth, Joost P.H., van Laarhoven, Cornelis J.H.M., Lantinga, Marten A., and de Reuver, Philip R.

Published
2023
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7. Stoma-free Survival After Rectal Cancer Resection With Anastomotic Leakage: Development and Validation of a Prediction Model in a Large International Cohort

Author

Greijdanus, Nynke G., Wienholts, Kiedo, Ubels, Sander, Talboom, Kevin, Hannink, Gerjon, Wolthuis, Albert, de Lacy, Francisco B., Lefevre, Jérémie H., Solomon, Michael, Frasson, Matteo, Rotholtz, Nicolas, Denost, Quentin, Perez, Rodrigo O., Konishi, Tsuyoshi, Panis, Yves, Rutegård, Martin, Hompes, Roel, Rosman, Camiel, van Workum, Frans, Tanis, Pieter J., de Wilt, Johannes H.W., Bremers, Andreas J.A., Ferenschild, Floris T., de Vriendt, Stefanie, D’Hoore, André, Bislenghi, Gabriele, Farguell, Jordi, Lacy, Antonio M., Atienza, Paula González, van Kessel, Charlotte S., Parc, Yann, Voron, Thibault, Collard, Maxime K., Muriel, Jorge Sancho, Cholewa, Hannia, Mattioni, Laura A., Frontali, Alice, Polle, Sebastiaan W., Polat, Fatih, Obihara, Ndidi J., Vailati, Bruna B., Kusters, Miranda, Tuynmann, Jurriaan B., Hazen, Sanne J.A., Grüter, Alexander A.J., Amano, Takahiro, Fujiwara, Hajime, Salomon, Mario, Ruiz, Hernán, Gonzalez, Ricardo, Estefanía, Diego, Avellaneda, Nicolas, Carrie, Augusto, Santillan, Mateo, Pantoja Pachajoa, Diana A., Parodi, Matias, Gielis, Manuel, Binder, Alf-Dorian, Gürtler, Thomas, Riedl, Peter, Badiani, Sarit, Berney, Christophe, Morgan, Matthew, Hollington, Paul, da Silva, Nigel, Nair, Gavin, Ho, Yiu M., Lamparelli, Michael, Kapadia, Raj, Kroon, Hidde M., Dudi-Venkata, Nagendra N., Liu, Jianliang, Sammour, Tarik, Flamey, Nicolas, Pattyn, Paul, Chaoui, Ahmed, Vansteenbrugge, Louis, van den Broek, Nathalie E.J., Vanclooster, Patrick, de Gheldere, Charles, Pletinckx, Pieter, Defoort, Barbara, Dewulf, Maxime, Slavchev, Mihail, Belev, Nikolay, Atanasov, Boyko, Krastev, Panche, Sokolov, Manol, Maslyankov, Svilen, Gribnev, Petar, Pavlov, Vasil, Ivanov, Tsvetomir, Karamanliev, Martin, Filipov, Emil, Tonchev, Pencho, Aigner, Felix, Mitteregger, Martin, Allmer, Caterina, Seitinger, Gerald, Colucci, Nicola, Buchs, Nicolas, Ris, Frédéric, Toso, Christian, Gialamas, Eleftherios, Vuagniaux, Aurélie, Chautems, Roland, Sauvain, Marc-Olivier, Daester, Silvio, von Flüe, Markus, Guenin, Marc-Olivier, Taha-Mehlitz, Stephanie, Hess, Gabriel F., Martínek, Lubomír, Skrovina, Matej, Machackova, Maria, Benčurik, Vladimir, Uluk, Deniz, Pratschke, Johann, Dittrich, Luca S., Guel-Klein, Safak, Perez, Daniel, Grass, Julia-Kristin, Melling, Nathaniel, Mueller, Simone, Iversen, Lene H., Eriksen, Jacob D., Baatrup, Gunnar, Al-Najami, Issam, Bjørsum-Meyer, Thomas, Teras, Jüri, Teras, Roland M., Monib, Fatma A., Abu Elnga Ahmed, Nagm Eldin, Alkady, Eithar, Ali, Ahmed K., Khedr, Gehan Abd Elatti, Abdelaal, Ahmed Samir, Bassyouni Ashoush, Fouad M., Ewedah, Moataz, Elshennawy, Eslam M., Hussein, Mohamed, Fernández-Martínez, Daniel, García-Flórez, Luis J., Fernández-Hevia, María, Suárez-Sánchez, Aida, del Hoyo Aretxabala, Izaskun, Docampo, Iria Losada, Zabala, Jesús Gómez, Tejedor, Patricia, Morales Bernaldo de Quirós, Javier T., Quiroga, Ignacio Bodega, Navarro-Sánchez, Antonio, Darias, Iván Soto, Fernández, Cristina López, de La Cruz Cuadrado, Cristina, Sánchez-Guillén, Luis, López-Rodríguez-Arias, Francisco, Soler-Silva, Álvaro, Arroyo, Antonio, Bernal-Sprekelsen, Juan C., Gómez-Abril, Segundo Á., Gonzálvez, Paula, Torres, María T., Sánchez, Teresa Rubio, Antona, Francisco Blanco, Sánchez Lara, Juan E., Alcázar Montero, José A., Fernández-Martínez, Daniel, García-Flórez, Luis J., Fernández-Hevia, María, Suárez-Sánchez, Aida, Colás-Ruiz, Enrique, Tasende-Presedo, Marta M., Fernández-Hurtado, Ignacio, Cifuentes-Ródenas, José A., Suárez, Marta Castro, Losada, Manuel, Hernández, Miguel, Alonso, Alfredo, Diéguez, Beatriz, Serralta, Daniel, Medina Quintana, Rita E., Gil Lopez, Jose M., Pinto, Francisca Lima, Nieto-Moreno, Elena, Bonito, Alba Correa, Santacruz, Carlos Cerdán, Marcos, Elena Bermejo, Septiem, Javier García, Calero-Lillo, Aránzazu, Alanez-Saavedra, Javier, Muñoz-Collado, Salvador, López-Lara, Manuel, Martínez, María Labalde, Herrero, Eduardo Ferrero, Borda, Francisco Javier García, Villar, Óscar García, Escartín, Jorge, Blas, Juan L., Ferrer, Rocío, Egea, Jorge García, Rodríguez-Infante, Antonio, Mínguez-Ruiz, Germán, Carreño-Villarreal, Guillermo, Pire-Abaitua, Gerardo, Dziakova, Jana, Rodríguez, Carlos Sáez-Cazallas, Pizarro Aranda, María J., Muguerza Huguet, José M., Borda-Arrizabalaga, Nerea, Enriquez-Navascués, José M., Echaniz, Garazi Elorza, Ansorena, Yolanda Saralegui, Estaire-Gómez, Mercedes, Martínez-Pinedo, Carlos, Barbero-Valenzuela, Alejandro, Ruíz-García, Pablo, Kraft, Miquel, Gómez-Jurado, María J., Pellino, Gianluca, Espín-Basany, Eloy, Cotte, Eddy, Panel, Nathalie, Goutard, Claire-Angéline, deÁngelis, Nicola, Lauka, Lelde, Shaikh, Shafaque, Osborne, Laura, Ramsay, George, Nichita, Vladimir-Ion, Bhandari, Santosh, Sarmah, Panchali, Bethune, Rob M., Pringle, Heather C.M., Massey, Lisa, Fowler, George E., Hamid, Hytham K.S., de Simone, Belinda D., Kynaston, James, Bradley, Nicholas, Stienstra, Roxane M., Gurjar, Shashank, Mukherjee, Tanmoy, Chandio, Ashfaq, Ahmed, Safia, Singh, Baljit, Runau, Francois, Chaudhri, Sanjay, Siaw, Oliver, Sarveswaran, Janahan, Miu, Victor, Ashmore, Daniel, Darwich, Haitham, Singh-Ranger, Deepak, Singh, Nirbhaibir, Shaban, Mohamed, Gareb, Fahed, Petropolou, Thalia, Polydorou, Adreas, Dattani, Mit, Afzal, Asma, Bavikatte, Akshay, Sebastian, Boby, Ward, Nicholas, Mishra, Amitabh, Manatakis, Dimitrios, Agalianos, Christos, Tasis, Nikolaos, Antonopoulou, Maria-Ioanna, Karavokyros, Ioannis, Charalabopoulos, Alexandros, Schizas, Dimitrios, Baili, Efstratia, Syllaios, Athanasios, Karydakis, Lysandros, Vailas, Michail, Balalis, Dimitrios, Korkolis, Dimitrios, Plastiras, Aris, Rompou, Aliki, Xenaki, Sofia, Xynos, Evangelos, Chrysos, Emmanuel, Venianaki, Maria, Christodoulidis, Grigorios, Perivoliotis, Konstantinos, Tzovaras, George, Baloyiannis, Ioannis, Ho, Man-Fung, Ng, Simon Siu-man, Mak, Tony Wing-chung, Futaba, Kaori, Šantak, Goran, Šimleša, Damir, osić, Jurica, Zukanović, Goran, Kelly, Michael E., Larkin, John O., McCormick, Paul H., Mehigan, Brian J., Connelly, Tara M., Neary, Peter, Ryan, Jessica, McCullough, Peter, Al-Juaifari, Maytham A., Hammoodi, Hayder, Abbood, Ali Hashim, Calabrò, Marcello, Muratore, Andrea, Terra, Antonio La, Farnesi, Francesca, Feo, Carlo V., Fabbri, Nicolò, Pesce, Antonio, Fazzin, Marta, Roscio, Francesco, Clerici, Federico, Lucchi, Andrea, Vittori, Laura, Agostinelli, Laura, Ripoli, Maria Cristina, Sambucci, Daniele, Porta, Andrea, Sinibaldi, Giovanni, Crescentini, Giacomo, larcinese, Antonella, Picone, Emanuele, Persiani, Roberto, Biondi, Alberto, Pezzuto, Roberto, Lorenzon, Laura, Rizzo, Gianluca, Coco, Claudio, D’Agostino, Luca, Spinelli, Antonino, Sacchi, Matteo M., Carvello, Michele, Foppa, Caterina, Spinelli, Antonino, Sacchi, Matteo M., Carvello, Michele, Foppa, Caterina, Maroli, Annalisa, Palini, Gian M., Garulli, Gianluca, Zanini, Nicola, Delrio, Paolo, Rega, Daniela, Carbone, Fabio, Aversano, Alessia, Pirozzolo, Giovanni, Recordare, Alfonso, DʼAlimonte, Lucrezia, Vignotto, Chiara, Corbellini, Carlo, Sampietro, Gianluca M., Lorusso, Leonardo, Manzo, Carlo A., Ghignone, Federico, Ugolini, Giampaolo, Montroni, Isacco, Pasini, Franceso, Pasini, Francesco, Ballabio, Michele, Bisagni, Pietro, Armao, Francesca T., Longhi, Marco, Ghazouani, Omar, Galleano, Raffaele, Tamini, Nicolò, Oldani, Massimo, Nespoli, Luca, Picciariello, Arcangelo, Altomare, Donato F., Tomasicchio, Giovanni, Lantone, Giuliano, Catena, Fausto, Giuffrida, Mario, Annicchiarico, Alfredo, Perrone, Gennaro, Grossi, Ugo, Santoro, Giulio A., Zanus, Giacomo, Iacomino, Alessandro, Novello, Simone, Passuello, Nicola, Zucchella, Martino, Puca, Lucia, deGiuli, Maurizio, Reddavid, Rossella, Scabini, Stefano, Aprile, Alessandra, Soriero, Domenico, Fioravanti, Emanuela, Rottoli, Matteo, Romano, Angela, Tanzanu, Marta, Belvedere, Angela, Mariani, Nicolò M., Ceretti, Andrea P., Opocher, Enrico, Gallo, Gaetano, Sammarco, Giuseppe, de Paola, Gilda, Pucciarelli, Salvatore, Marchegiani, Francesco, Spolverato, Gaya, Buzzi, Gianluca, Di Saverio, Salomone, Meroni, Paola, Parise, Cristiano, Bottazzoli, Elisa I., Lapolla, Pierfrancesco, Brachini, Gioia, Cirillo, Bruno, Mingoli, Andrea, Sica, Giuseppe, Siragusa, Leandro, Bellato, Vittoria, Cerbo, Daniele, de Pasqual, Carlo A., de Manzoni, Giovanni, di Cosmo, Maria A., Alrayes, Bourhan M.H., Qandeel, Mahmoud W. M., Hani, Mohammad Bani, Rabadi, Alexander, el Muhtaseb, Mohammad S., Abdeen, Basel, Karmi, Fahed, Žilinskas, Justas, Latkauskas, Tadas, Tamelis, Algimantas, Pikūnienė, Ingrida, Šlenfuktas, Vygintas, Poskus, Tomas, Kryzauskas, Marius, Jakubauskas, Matas, Mikalauskas, Saulius, Jakubauskiene, Lina, Hassan, Soha Y., Altrabulsi, Amani, Abdulwahed, Eman, Ghmagh, Reem, Deeknah, Abdulqudus, Alshareea, Entisar, Elhadi, Muhammed, Abujamra, Saleh, Msherghi, Ahmed A., Tababa, Osama W.E., Majbar, Mohammed A., Souadka, Amine, Benkabbou, Amine, Mohsine, Raouf, Echiguer, Sabrillah, Moctezuma-Velázquez, Paulina, Salgado-Nesme, Noel, Vergara-Fernández, Omar, Sainz-Hernández, Juan C., Alvarez-Bautista, Francisco E., Zakaria, Andee D., Zakaria, Zaidi, Wong, Michael P.K., Ismail, Razif, Ibrahim, Aini F., Abdullah, Nik A.N., Julaihi, Rokayah, Bhat, Sameer, OʼGrady, Greg, Bissett, Ian, Lamme, Bas, Musters, Gijsbert D., Dinaux, Anne M., Grotenhuis, Brechtje A., Steller Arend G.J. Aalbers, Ernst J., Leeuwenburgh, Marjolein M., Rutten, Harm J.T., Burger, Jacobus W.A., Bloemen, Johanne G., Ketelaers, Stijn H.J., Waqar, Usama, Chawla, Tabish, Rauf, Hareem, Rani, Pallavi, Talsma, Aaldert K., Scheurink, Lieke, van Praagh, Jasper B., Segelman, Josefin, Nygren, Jonas, Anderin, Kajsa, Tiefenthal, Marit, de Andrés, Beatriz, Beltrán de Heredia, Juan P., Vázquez, Andrea, Gómez, Tania, Golshani, Parisa, Kader, Rawaz, Mohamed, Abudi, Westerterp, Marinke, Marinelli, Andreas, Niemer, Quirine, Doornebosch, Pascal G., Shapiro, Joël, Vermaas, Maarten, de Graaf, Eelco J.R., van Westreenen, Hendrik L., Zwakman, Marije, van Dalsen, Annette D., Vles, Wouter J., Nonner, Joost, Toorenvliet, Boudewijn R., Janssen, Paul T.J., Verdaasdonk, Emiel G.G., Amelung, Femke J., Peeters Renu R. Bahadoer, Koen C.M.J., Holman, Fabian A., Heemskerk, Jeroen, Vosbeek, Noortje, Leijtens, Jeroen W.A., Taverne, Sophie B.M., Heijnen, Bob H.M., El-Massoudi, Youssef, de Groot-van Veen, Irene, Hoff, Christiaan, Jou-Valencia, Daniela, Consten, Esther C.J., Burghgraef, Thijs A., Geitenbeek, Ritch, Hulshof, Lorenzo G.W.L., Slooter, Gerrit D., Reudink, Muriël, Bouvy, Nicole D., Wildeboer, Aurelia C. L., Verstappen, Sonja, Pennings, Alexander J., van den Hengel, Berber, Wijma, Allard G., de Haan, Jael, de Nes, Lindsey C.F., Heesink, Vera, Karsten, Tom, Heidsma, Charlotte M., Koemans, Willem J., Dekker, Jan-Willem T., van der Zijden, Charlène J., Roos, Daphne, Demirkiran, Ahmet, van der Burg, Sjirk, Oosterling, Steven J., Hoogteijling, Tijs J., Wiering, Bastiaan, Smeeing, Diederik P.J., Havenga, Klaas, Lutfi, Hamid, Consten, Esther C.J., Tsimogiannis, Konstantinos, Sköldberg, Filip, Folkesson, Joakim, den Boer, Frank, van Schaik, Ted G., van Gerven, Pieter, Sietses, Colin, Hol, Jeroen C., Boerma, Evert-Jan G., Creemers, Davy M.J., Schultz, Johannes K., Frivold, Tone, Riis, Rolf, Gregussen, Hilde, Busund, Sondre, Sjo, Ole H., Gaard, Maria, Krohn, Nina, Ersryd, Amanda L., Leung, Edmund, Waqar, Usama, Chawla, Tabish, Rauf, Hareem, Rani, Pallavi, Sultan, Hytham, Hajjaj, Baraa Nabil, Alhisi, Ahmed Jehad, Khader, Ahmed A.E., Mendes, Ana Filipa Dias, Semião, Miguel, Faria, Luis Queiroz, Azevedo, Constança, da Costa Devesa, Helena M., Martins, Sónia Fortuna, Rodrigues Jarimba, Aldo M., Ribeiro Marques, Sónia M., Ferreira, Rita Marques, Oliveira, António, Ferreira, Cátia, Pereira, Ricardo, Surlin, Valeriu M., Graure, Giorgiana M., Ramboiu, Stefan Patrascu Sandu D., Negoi, Ionut, Ciubotaru, Cezar, Stoica, Bogdan, Tanase, Ioan, Stoica, Bogdan, Ciubotaru, Cezar, Negoita, Valentina M., Florea, Sabrina, Macau, Florin, Vasile, Mihai, Stefanescu, Victor, Dimofte, Gabriel-Mihail, Luncă, Sorinel, Roată, Cristian-Ene, Mu[Latin Small Letter s with comma below]ină, Ana-Maria, Garmanova, Tatiana, Agapov, Mikhail N., Markaryan, Daniil G., Eduard, Galliamov, Yanishev, Alexey, Abelevich, Alexander, Bazaev, Andrey, Rodimov, Sergey V., Filimonov, Victor B., Melnikov, Andrey A., Suchkov, Igor A., Drozdov, EvgeniyS., Kostromitskiy, Dmitriy N., Sjöström, Olle, Matthiessen, Peter, Baban, Bayar, Gadan, Soran, Jadid, Kaveh Dehlaghi, Staffan, Maria, Park, Jennifer M., Rydbeck, Daniel, Lydrup, Marie-Louise, Buchwald, Pamela, Jutesten, Henrik, Darlin, Lotten, Lindqvist, Ebba, Nilsson, Karl, Larsson, Per-Anders, Jangmalm, Staffan, Košir, Jurij A., Tomažič, Aleš, Grosek, Jan, Božič, Tajda Košir, Zazo, Aya, Zazo, Rama, Fares, Hala, Ayoub, Kusay, Niazi, Ammar, Mansour, Ali, Abbas, Ayman, Tantoura, Mohammad, Hamdan, Alaa, Hassan, Naya, Hasan, Bassam, Saad, Ahmad, Sebai, Amine, Haddad, Anis, Maghrebi, Houcine, Kacem, Montasser, Yalkın, Ömer, Samsa, Mehmet Veysi, Atak, İbrahim, Balci, Bengi, Haberal, Elifcan, Dogan, Lütfi, Gecim, Ibrahim E., Akyol, Cihangir, Koc, Mehmet A., Sivrikoz, Emre, Piyadeoğlu, Deniz, Larkin, John O., avanagh, Dara O., Sökmen, Selman, Bişgin, Tayfun, Günenç, Erşan, Güzel, Melek, Leventoğlu, Sezai, Yüksel, Osman, Kozan, Ramazan, Göbüt, Hüseyin, Cengiz, Fevzi, Erdinc, Kemal, Acar, Nihan Coşgun, Kamer, Erdinc, Özgür, İlker, Aydın, Oguzhan, Keskin, Metin, Bulut, Mehmet Türker, Kulle, Cemil B., Kara, Yasin, Sıbıç, Osman, Özata, İbrahim H., Buğra, Dursun, Balık, Emre, Kulle, Cemil B., Çakır, Murat, Alhardan, Anas, Colak, Elif, CiftciEngin Aybar, Ahmet B., Sari, Ahmet Can, Atici, Semra Demirli, Kaya, Tayfun, Dursun, Ayberk, Calik, Bulent, Özkan, Ömer Faruk, Ülgür, Hanife Şeyda, Düzgün, Özgül, Monson, John, George, Sarah, Woods, Kayla, Al-Eryani, Fatima, Albakry, Rudaina, Coetzee, Emile, Boutall, Adam, Herman, Ayesiga, Warden, Claire, Mugla, Naser, Forgan, Tim, Mia, Imraan, and Lambrechts, Anton

Published
2023
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11. Trends in Distal Esophageal and Gastroesophageal Junction Cancer Care: The Dutch Nationwide Ivory Study

Author

Kalff, Marianne C., van Berge Henegouwen, Mark I., Baas, Peter C., Bahadoer, Renu R., Belt, Eric J. T., Brattinga, Baukje, Claassen, Linda, Ćosović, Admira, Crull, David, Daams, Freek, van Dalsen, Annette D., Dekker, Jan Willem T., van Det, Marc J., Drost, Manon, van Duijvendijk, Peter, Eshuis, Wietse J., van Esser, Stijn, Gaspersz, Marcia P., Görgec, Burak, Groenendijk, Richard P. R., Hartgrink, Henk H., van der Harst, Erwin, Haveman, Jan Willem, Heisterkamp, Joos, van Hillegersberg, Richard, Kelder, Wendy, Kingma, B. Feike, Koemans, Willem J., Kouwenhoven, Ewout A., Lagarde, Sjoerd M., Lecot, Frederik, van der Linden, Philip P., Luyer, Misha D. P., Nieuwenhuijzen, Grard A. P., Olthof, Pim B., van der Peet, Donald L., Pierie, Jean-Pierre E. N., Pierik, E. G. J. M. Robert, Plat, Victor D., Polat, Fatih, Rosman, Camiel, Ruurda, Jelle P., van Sandick, Johanna W., Scheer, Rene, Slootmans, Cettela A. M., Sosef, Meindert N., Sosef, Odin V., de Steur, Wobbe O., Stockmann, Hein B. A. C., Stoop, Fanny J., Voeten, Daan M., Vugts, Guusje, Vijgen, Guy H. E. J., Weeda, Víola B., Wiezer, Marinus J., van Oijen, Martijn G. H., and Gisbertz, Suzanne S.

Published
2023
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14. Quality of Recovery and Innate Immune Homeostasis in Patients Undergoing Low-pressure Versus Standard-pressure Pneumoperitoneum During Laparoscopic Colorectal Surgery (RECOVER): A Randomized Controlled Trial

Author

Albers, Kim I., Polat, Fatih, Helder, Leonie, Panhuizen, Ivo F., Snoeck, Marc M.J., Polle, S. (Bas) W., de Vries, Hilbert, Dias, Esther M., Slooter, Gerrit D., de Boer, Hans D., Diaz-Cambronero, Oscar, Mazzinari, Guido, Scheffer, Gert-Jan, Keijzer, Christiaan, Warlé, Michiel C., Bindels, Manon, Bökkerink, Guus M.J., Graat, Leon J., Groh, Laszlo A., van Helden, Esmee, Leclercq, Wouter K.G., Marques Mari, Ana I., Meijer, Patrick, Reijnders, Gabby, and de Zeeuw, Sharonne

Published
2022
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15. Recurrent Disease After Esophageal Cancer Surgery: A Substudy of The Dutch Nationwide Ivory Study

Author

Kalff, Marianne C., Henckens, Sofie P.G., Voeten, Daan M., Heineman, David J., Hulshof, Maarten C.C.M., van Laarhoven, Hanneke W.M., Eshuis, Wietse J., Baas, Peter C., Bahadoer, Renu R., Belt, Eric J.T., Brattinga, Baukje, Claassen, Linda, Ćosović, Admira, Crull, David, Daams, Freek, van Dalsen, Annette D., Dekker, Jan Willem T., van Det, Marc J., Drost, Manon, van Duijvendijk, Peter, van Esser, Stijn, Gaspersz, Marcia P., Görgec, Burak, Groenendijk, Richard P.R., Hartgrink, Henk H., van der Harst, Erwin, Haveman, Jan W., Heisterkamp, Joos, van Hillegersberg, Richard, Kelder, Wendy, Kingma, B. Feike, Koemans, Willem J., Kouwenhoven, Ewout A., Lagarde, Sjoerd M., Lecot, Frederik, van der Linden, Philip P., Luyer, Misha D.P., Nieuwenhuijzen, Grard A.P., Olthof, Pim B., van der Peet, Donald L., Pierie, Jean-Pierre E.N., Pierik, E.G.J.M. Robert, Plat, Victor D., Polat, Fatih, Rosman, Camiel, Ruurda, Jelle P., van Sandick, Johanna W., Scheer, Rene, Slootmans, Cettela A.M., Sosef, Meindert N., Sosef, Odin V., de Steur, Wobbe O., Stockmann, Hein B.A.C., Stoop, Fanny J., Vugts, Guusje, Vijgen, Guy H.E.J., Weeda, Víola B., Wiezer, Marinus J., van Oijen, Martijn G.H., van Berge Henegouwen, Mark I., and Gisbertz, Suzanne S.

Published
2022
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16. Total mesorectal excision in MRI-defined low rectal cancer: multicentre study comparing oncological outcomes of robotic, laparoscopic and transanal total mesorectal excision in high-volume centres

Author

Rutgers, Marieke L, primary, Burghgraef, Thijs A, additional, Hol, Jeroen C, additional, Crolla, Rogier M, additional, van Geloven, Nanette A, additional, Leijtens, Jeroen W, additional, Polat, Fatih, additional, Pronk, Apollo, additional, Smits, Anke B, additional, Tuyman, Jurriaan B, additional, Verdaasdonk, Emiel G, additional, Sietses, Colin, additional, Consten, Esther C, additional, and Hompes, Roel, additional

Published
2024
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17. Trends in Distal Esophageal and Gastroesophageal Junction Cancer Care: The Dutch Nationwide Ivory Study

Author

Kalff, Marianne C., Henegouwen, Mark I. van Berge, Baas, Peter C., Bahadoer, Renu R., Belt, Eric J. T., Brattinga, Baukje, Claassen, Linda, Ćosović, Admira, Crull, David, Daams, Freek, van Dalsen, Annette D., Dekker, Jan Willem T., van Det, Marc J., Drost, Manon, van Duijvendijk, Peter, Eshuis, Wietse J., van Esser, Stijn, Gaspersz, Marcia P., Görgec, Burak, Groenendijk, Richard P. R., Hartgrink, Henk H., van der Harst, Erwin, Haveman, Jan Willem, Heisterkamp, Joos, van Hillegersberg, Richard, Kelder, Wendy, Kingma, B. Feike, Koemans, Willem J., Kouwenhoven, Ewout A., Lagarde, Sjoerd M., Lecot, Frederik, van der Linden, Philip P., Luyer, Misha D. P., Nieuwenhuijzen, Grard A. P., Olthof, Pim B., van der Peet, Donald L., Pierie, Jean-Pierre E. N., Pierik, E. G. J. M. Robert, Plat, Victor D., Polat, Fatih, Rosman, Camiel, Ruurda, Jelle P., van Sandick, Johanna W., Scheer, Rene, Slootmans, Cettela A. M., Sosef, Meindert N., Sosef, Odin V., de Steur, Wobbe O., Stockmann, Hein B. A. C., Stoop, Fanny J., Voeten, Daan M., Vugts, Guusje, Vijgen, Guy H. E. J., Weeda, Víola B., Wiezer, Marinus J., van Oijen, Martijn G. H., and Gisbertz, Suzanne S.

Published
2021
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19. Learning Curves of Ivor Lewis Totally Minimally Invasive Esophagectomy by Hospital and Surgeon Characteristics: A Retrospective Multinational Cohort Study

Author

Claassen, Linda, Hannink, Gerjon, Luyer, Misha D. P., Ainsworth, Alan P., van Berge Henegouwen, Mark I., Cheong, Edward, Daams, Freek, van Det, Marc J., van Duijvendijk, Peter, Gisbertz, Suzanne S., Gutschow, Christian A., Heisterkamp, Joos, Kauppi, Juha T., Klarenbeek, Bastiaan R., Kouwenhoven, Ewout A., Langenhoff, Barbara S., Larsen, Michael H., Martijnse, Ingrid S., Nieuwenhoven, Ernst Jan van, van der Peet, Donald L., Pierie, Jean-Pierre E. N., Pierik, Robert E. G. J. M., Polat, Fatih, Räsänen, Jari V., Rouvelas, Ioannis, Sosef, Meindert N., Wassenaar, Eelco B., Wildenberg, Frits J. H. van den, van der Zaag, Edwin S., Nilsson, Magnus, Nieuwenhuijzen, Grard A. P., van Workum, Frans, and Rosman, Camiel

Published
2022
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20. Prognostic significance of MRI-detected extramural venous invasion according to grade and response to neo-adjuvant treatment in locally advanced rectal cancer A national cohort study after radiologic training and reassessment

Author

Geffen, Eline G.M. van, primary, Nederend, Joost, additional, Sluckin, Tania C., additional, Hazen, Sanne-Marije J.A., additional, Horsthuis, Karin, additional, Beets-Tan, Regina G.H., additional, Marijnen, Corrie A.M., additional, Tanis, Pieter J., additional, Kusters, Miranda, additional, Aalbers, Arend G.J., additional, van Aalten, Susanna M., additional, Amelung, Femke J., additional, Ankersmit, Marjolein, additional, Antonisse, Imogeen E., additional, Ashruf, Jesse F., additional, Aukema, Tjeerd S., additional, Avenarius, Henk, additional, Bahadoer, Renu R., additional, Bakers, Frans C.H., additional, Bakker, Ilsalien S., additional, Bangert, Fleur, additional, Barendse, Renée M., additional, Beekhuis, Heleen M.D., additional, Beets, Geerard L., additional, Bemelman, Willem A., additional, Berbée, Maaike, additional, de Bie, Shira H., additional, Bisschops, Robert H.C., additional, Blok, Robin D., additional, van Bockel, Liselotte W., additional, Boer, Anniek H., additional, den Boer, Frank C., additional, Boerma, Evert-Jan G., additional, Boogerd, Leonora S.F., additional, Borstlap, Jaap, additional, Borstlap, Wernard A.A., additional, Bouwman, Johanna E., additional, Braak, Sicco J., additional, Braat, Manon N.G.J.A., additional, Bradshaw, Jennifer, additional, Brandsma, Amarins T.A., additional, van Breest Smallenburg, Vivian, additional, van den Broek, Wim T., additional, van der Burg, Sjirk W., additional, Burger, Jacobus W.A., additional, Burghgraef, Thijs A., additional, ten Cate, David W.G., additional, Ceha, Heleen M., additional, Cnossen, Jeltsje S., additional, Coebergh van den Braak, Robert R.J., additional, Consten, Esther C.J., additional, Corver, Maaike, additional, Crolla, Rogier M.P.H., additional, Curutchet, Sam, additional, Daniëls-Gooszen, Alette W., additional, Davids, Paul H.P., additional, Dekker, Emmelie N., additional, Dekker, Jan Willem T., additional, Demirkiran, Ahmet, additional, Derksen, Tyche, additional, Diederik, Arjen L., additional, Dinaux, Anne M., additional, Dogan, Kemal, additional, van Dop, Ilse M., additional, Droogh-de Greve, Kitty E., additional, Duijsens, Hanneke M.H., additional, Dunker, Michalda S., additional, Duyck, Johan, additional, van Duyn, Eino B., additional, van Egdom, Laurentine S.E., additional, Eijlers, Bram, additional, El-Massoudi, Youssef, additional, van Elderen, Saskia, additional, Emmen, Anouk M.L.H., additional, Engelbrecht, Marc, additional, van Erp, Anne C., additional, van Essen, Jeroen A., additional, Fabry, Hans F.J., additional, Fassaert, Thomas, additional, Feitsma, Eline A., additional, Feshtali, Shirin S., additional, Frietman, Bas, additional, Furnée, Edgar J.B., additional, van Geel, Anne M., additional, Geijsen, Elisabeth D., additional, van Geloven, Anna A.W., additional, Gerhards, Michael F., additional, Gielkens, Hugo, additional, van Gils, Renza A.H., additional, Goense, Lucas, additional, Govaert, Marc J.P.M., additional, van Grevenstein, Wilhelmina M.U., additional, Joline de Groof, E., additional, de Groot, Irene, additional, de Haas, Robbert J., additional, Hakkenbrak, Nadia A.G., additional, den Hartogh, Mariska D., additional, Heesink, Vera, additional, Heikens, Joost T., additional, Hendriksen, Ellen M., additional, van den Hoek, Sjoerd, additional, van der Hoeven, Erik J.R.J., additional, Hoff, Christiaan, additional, Hogewoning, Anna, additional, Hogewoning, Cornelis R.C., additional, Hoogendoorn, Stefan, additional, van Hoorn, Francois, additional, van der Hul, René L., additional, van Hulst, Rieke, additional, Imani, Farshad, additional, Inberg, Bas, additional, Intven, Martijn P.W., additional, Janssen, Pedro, additional, de Jong, Chris E.J., additional, Jonkers, Jacoline, additional, Jou-Valencia, Daniela, additional, Keizers, Bas, additional, Ketelaers, Stijn H.J., additional, Knöps, Eva, additional, van Koeverden, Sebastiaan, additional, Kok, Sylvia, additional, Kolderman, Stephanie E.M., additional, de Korte, Fleur I., additional, Kortekaas, Robert T.J., additional, Korving, Julie C., additional, Koster, Ingrid M., additional, Krdzalic, Jasenko, additional, Krielen, Pepijn, additional, Kroese, Leonard F., additional, Krul, Eveline J.T., additional, Lahuis, Derk H.H., additional, Lamme, Bas, additional, van Landeghem, An A.G., additional, Leijtens, Jeroen W.A., additional, Leseman-Hoogenboom, Mathilde M., additional, de Lijster, Manou S., additional, Marsman, Martijn S., additional, Martens, MilouH., additional, Masselink, Ilse, additional, van der Meij, Wout, additional, Meijnen, Philip, additional, Melenhorst, Jarno, additional, de Mey, Dietrich J.L., additional, Moelker-Galuzina, Julia, additional, Morsink, Linda, additional, Mulder, Erik J., additional, Muller, Karin, additional, Musters, Gijsbert D., additional, Neijenhuis, Peter A., additional, de Nes, Lindsey C.F., additional, Nielen, M., additional, van den Nieuwboer, Jan B.J., additional, Nieuwenhuis, Jonanne F., additional, Nonner, Joost, additional, Noordman, Bo J., additional, Nordkamp, Stefi, additional, Olthof, Pim B., additional, Oosterling, Steven J., additional, Ootes, Daan, additional, Oppedijk, Vera, additional, Ott, Pieter, additional, Paulusma, Ida, additional, Peeters, Koen C.M.J., additional, Pereboom, Ilona T.A., additional, Peringa, Jan, additional, Pironet, Zoë, additional, Plate, Joost D.J., additional, Polat, Fatih, additional, Poodt, Ingrid G.M., additional, Posma, Lisanne A.E., additional, Prette, Jeroen F., additional, Pultrum, Bareld B., additional, Qaderi, Seyed M., additional, van Rees, Jan M., additional, Renger, Rutger-Jan, additional, Rombouts, Anouk J.M., additional, Roosen, Lodewijk J., additional, Roskott-ten Brinke, Ellen A., additional, Rothbarth, Joost, additional, Rouw, Dennis B., additional, Rozema, Tom, additional, Rütten, Heidi, additional, Rutten, Harm J.T., additional, van der Sande, Marit E., additional, Schaafsma, Boudewijn E., additional, Schasfoort, Renske A., additional, Scheurkogel, Merel M., additional, Schouten van der Velden, Arjan P., additional, Schreurs, Wilhelmina H., additional, Schuivens, Puck M.E., additional, Sietses, Colin, additional, Simons, Petra C.G., additional, Slob, Marjan J., additional, Slooter, Gerrit D., additional, van der Sluis, Martsje, additional, Smalbroek, Bo P., additional, Smits, Anke B., additional, Spillenaar-Bilgen, Ernst J., additional, Spruit, Patty H., additional, Stam, Tanja C., additional, Stoker, Jaap, additional, Talsma, Aaldert K., additional, Temmink, Sofieke J.D., additional, The, G.Y. Mireille, additional, Tielbeek, Jeroen A.W., additional, van Tilborg, Aukje A.J.M., additional, van Tilborg, Fiek, additional, van Trier, Dorothée, additional, Tuynman, Jurriaan B., additional, van der Valk, Maxime J.M., additional, Vanhooymissen, Inge J.S., additional, Vasbinder, G. Boudewijn C., additional, Veeken, Cornelis J., additional, Velema, Laura A., additional, van de Ven, Anthony W.H., additional, Verdaasdonk, Emiel G.G., additional, Verduin, Wouter M., additional, Verhagen, Tim, additional, Verheijen, Paul M., additional, Vermaas, Maarten, additional, Verrijssen, An-Sofie E., additional, Verschuur, Anna V.D., additional, Schaik, Harmke Verwoerd-van, additional, Vliegen, Roy F.A., additional, Voets, Sophie, additional, Vogelaar, F. Jeroen, additional, Vogelij, Clementine L.A., additional, Vos-Westerman, Johanna, additional, de Vries, Marianne, additional, Vroemen, Joy C., additional, van Vugt, Bas S.T., additional, Wegdam, Johannes A., additional, van Wely, Bob J., additional, Westerterp, Marinke, additional, van Westerveld, Paul P., additional, van Westreenen, Henderik L., additional, Wijma, Allard G., additional, de Wilt, Johannes H.W., additional, de Wit, Bart W.K., additional, Wit, Fennie, additional, Woensdregt, Karlijn, additional, van Woerden, Victor, additional, van der Wolf, Floor S.W., additional, van der Wolk, Sander, additional, Wybenga, Johannes M., additional, van der Zaag, Edwin S., additional, Zamaray, Bobby, additional, Zandvoort, Herman J.A., additional, van der Zee, Dennis, additional, Zeilstra, Annette P., additional, Zheng, Kang J., additional, Zimmerman, David D.E., additional, and Zorgdrager, Marcel, additional

Published
2024
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22. TÜRK EDEBİYATINDA "HÂTİFÎ" MAHLASLI ŞAİRLER VE "RÂHATÜ’L-ERVÂH".

Author

Polat, Fatih

Subjects
BIOGRAPHIES of authors, SIXTEENTH century, RESEARCH personnel, ANONYMS & pseudonyms, POETS
Abstract

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Published
2024
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24. Persistent and new-onset symptoms after cholecystectomy in patients with uncomplicated symptomatic cholecystolithiasis: A post hoc analysis of 2 prospective clinical trials

Author

Thunnissen, Floris M., primary, Baars, Cléo, additional, Arts, Rianne, additional, Latenstein, Carmen S.S., additional, Drenth, Joost P.H., additional, van Laarhoven, Cornelis J.H.M., additional, Lantinga, Marten A., additional, de Reuver, Philip R., additional, Buyne, Otmar, additional, Donkervoort, Sandra C., additional, Heisterkamp, Joos, additional, ’t Hof, Klaas in, additional, Jansen, Jan, additional, Nieuwenhuijs, Vincent B., additional, Schaap, Henk M., additional, Steenvoorde, Pascal, additional, Boerma, Djamila, additional, Hazebroek, Eric J., additional, Hirsch, David, additional, Heikens, Joost T., additional, Konsten, Joop, additional, Polat, Fatih, additional, van der Bilt, Jarmila D.W., additional, Schreinemakers, Jennifer M.J., additional, Wiering, Bastiaan, additional, Stockmann, Hein B.A.C., additional, and Boermeester, Marja, additional

Published
2023
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25. Perineal wound closure using gluteal turnover flap or primary closure after abdominoperineal resection for rectal cancer: study protocol of a randomised controlled multicentre trial (BIOPEX-2 study)

Author

Sharabiany, Sarah, Blok, Robin D., Lapid, Oren, Hompes, Roel, Bemelman, Wilhelmus A., Alberts, Victor P., Lamme, Bas, Wijsman, Jan H., Tuynman, Jurriaan B., Aalbers, Arend G. J., Beets, Geerard L., Fabry, Hans F. J., Cherepanin, Ivan M., Polat, Fatih, Burger, Jacobus W. A., Rutten, Harm J. T., Bosker, Robert J. I., Talsma, Koen, Rothbarth, Joost, Verhoef, Cees, van de Ven, Anthony W. H., van der Bilt, Jarmila D. W., de Graaf, Eelco J. R., Doornebosch, Pascal G., Leijtens, Jeroen W. A., Heemskerk, Jeroen, Singh, Baljit, Chaudhri, Sanjay, Gerhards, Michael F., Karsten, Tom M., de Wilt, Johannes H. W., Bremers, Andre J. A., Vuylsteke, Ronald J. C. L. M., Heuff, Gijsbert, van Geloven, Anna A. W., Tanis, Pieter J., and Musters, Gijsbert D.

Published
2020
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28. Erratum to “Practice variation in anastomotic leak after esophagectomy: Unravelling differences in failure to rescue” [Eur J Surg Oncol 49 (5) (May 2023) 974–982]

Author

Ubels, Sander, primary, Matthée, Eric, additional, Verstegen, Moniek, additional, Klarenbeek, Bastiaan, additional, Bouwense, Stefan, additional, van Berge Henegouwen, Mark I., additional, Daams, Freek, additional, Dekker, Jan Willem T., additional, van Det, Marc J., additional, van Esser, Stijn, additional, Griffiths, Ewen A., additional, Haveman, Jan Willem, additional, Nieuwenhuijzen, Grard, additional, Siersema, Peter D., additional, Wijnhoven, Bas, additional, Hannink, Gerjon, additional, van Workum, Frans, additional, Rosman, Camiel, additional, Heisterkamp, Joos, additional, Polat, Fatih, additional, Schouten, Jeroen, additional, Singh, Pritam, additional, Slootmans, Cettela A.M., additional, Ultee, Gijs, additional, Gisbertz, Suzanne S., additional, Eshuis, Wietse J., additional, Kalff, Marianne C., additional, Feenstra, Minke L., additional, van der Peet, Donald L., additional, Stam, Wessel T., additional, Van Etten, Boudewijn, additional, Poelmann, Floris, additional, Vuurberg, Nienke, additional, Willem van den Berg, Jan, additional, Martijnse, Ingrid S., additional, Matthijsen, Robert M., additional, Luyer, Misha, additional, Curvers, Wout, additional, Nieuwenhuijzen, Tom, additional, Taselaar, Annick E., additional, Kouwenhoven, Ewout A., additional, Lubbers, Merel, additional, Sosef, Meindert, additional, Lecot, Frederik, additional, Geraedts, Tessa C.M., additional, van den Wildenberg, Frits, additional, Kelder, Wendy, additional, Baas, Peter C., additional, de Haas, Job W.A., additional, Hartgrink, Henk H., additional, Bahadoer, Renu R., additional, van Sandick, Johanna W., additional, Hartemink, Koen J., additional, Veenhof, Xander, additional, Stockmann, Hein, additional, Gorgec, Burak, additional, Weeder, Pepijn, additional, Wiezer, Marinus J., additional, Genders, Charlotte M.S., additional, Belt, Eric, additional, Blomberg, Bjorn, additional, van Duijvendijk, Peter, additional, Claassen, Linda, additional, Reetz, David, additional, Steenvoorde, Pascal, additional, Mastboom, Walter, additional, Klein Ganseij, Henk Jan, additional, van Dalsen, Annette D., additional, Joldersma, Annalie, additional, Zwakman, Marije, additional, Groenendijk, Richard P.R., additional, Montazeri, Mahsa, additional, Mercer, Stuart, additional, Knight, Benjamin, additional, van Boxel, Gijs, additional, McGregor, Richard J., additional, Skipworth, Richard J.E., additional, Frattini, Cristina, additional, Bradley, Alice, additional, Nilsson, Magnus, additional, Hayami, Masaru, additional, Huang, Biying, additional, Bundred, James, additional, Evans, Richard, additional, Grimminger, Peter P., additional, van der Sluis, Pieter C., additional, Eren, Uzun, additional, Saunders, John, additional, Theophilidou, Elena, additional, Khanzada, Zubair, additional, Elliott, Jessie A., additional, Ponten, Jeroen, additional, King, Sinead, additional, Reynolds, John V., additional, Sgromo, Bruno, additional, Akbari, Khalid, additional, Shalaby, Samar, additional, Gutschow, Christian A., additional, Schmidt, Henner, additional, Vetter, Diana, additional, Moorthy, Krishna, additional, Ibrahim, Mohamed A.H., additional, Christodoulidis, Grigorious, additional, Räsänen, Jari V., additional, Kauppi, Juha, additional, Söderström, Henna, additional, Koshy, Renol, additional, Manatakis, Dimitrios K., additional, Korkolis, Dimitrios P., additional, Balalis, Dimitrios, additional, Rompu, Aliki, additional, Alkhaffaf, Bilal, additional, Alasmar, Mohamed, additional, Arebi, Moaad, additional, Piessen, Guillaume, additional, Nuytens, Frederiek, additional, Degisors, Sebastien, additional, Ahmed, Ahmed, additional, Boddy, Alex, additional, Gandhi, Suraj, additional, Fashina, Oluwatomini, additional, Van Daele, Elke, additional, Pattyn, Piet, additional, Robb, William B., additional, Arumugasamy, Mayilone, additional, Al Azzawi, Mohammed, additional, Whooley, Jack, additional, Colak, Elif, additional, Aybar, Engin, additional, Sari, Ahmet C., additional, Uyanik, Mustafa S., additional, Ciftci, Ahmet B., additional, Sayyed, Raza, additional, Ayub, Bushra, additional, Murtaza, Ghulam, additional, Saeed, Aniqa, additional, Ramesh, Priyanka, additional, Charalabopoulos, Alexandros, additional, Liakakos, Theodore, additional, Schizas, Dimitrios, additional, Baili, Efstratia, additional, Kapelouzou, Alkistis, additional, Valmasoni, Michele, additional, Pierobon, Elisa Sefora, additional, Capovilla, Giovanni, additional, Merigliano, Stefano, additional, Constantinoiu, Silviu, additional, Birla, Rodica, additional, Achim, Florin, additional, Rosianu, Cristian Gelu, additional, Hoara, Petre, additional, Castro, Raúl Guevara, additional, Salcedo, Andrés Felipe, additional, Negoi, Ionut, additional, Negoita, Valentina M., additional, Ciubotaru, Cezar, additional, Stoica, Bogdan, additional, Hostiuc, Sorin, additional, Colucci, Nicola, additional, Mönig, Stefan P., additional, Wassmer, Charles-Henri, additional, Meyer, Jeremy, additional, Takeda, Flavio Roberto, additional, Aissar Sallum, Rubens Antonio, additional, Ribeiro, Ulysses, additional, Cecconello, Ivan, additional, Toledo, Enrique, additional, Trugeda, Maria Soledad, additional, Fernández, María José, additional, Gil, Carolina, additional, Castanedo, Sonia, additional, Isik, Arda, additional, Kurnaz, Eray, additional, Videira, José Flávio, additional, Peyroteo, Mariana, additional, Canotilho, Rita, additional, Weindelmayer, Jacopo, additional, Giacopuzzi, Simone, additional, De Pasqual, Carlo Alberto, additional, Bruna, Marcos, additional, Mingol, Fernando, additional, Vaque, Javier, additional, Pérez, Carla, additional, Phillips, Alexander W., additional, Chmelo, Jakub, additional, Brown, Joshua, additional, Han, Laura E., additional, Gossage, James A., additional, Davies, Andrew R., additional, Baker, Cara R., additional, Kelly, Mark, additional, Saad, Mohamed, additional, Bernardi, Daniele, additional, Bonavina, Luigi, additional, Asti, 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2023
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30. Stoma-free Survival After Rectal Cancer Resection With Anastomotic Leakage: Development and Validation of a Prediction Model in a Large International Cohort

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Nynke G, Greijdanu, Kiedo, Wienholt, Sander, Ubel, Kevin, Talboom, Gerjon, Hannink, Albert, Wolthui, Francisco B, de Lacy, Jérémie H, Lefevre, Michael, Solomon, Matteo, Frasson, Nicolas, Rotholtz, Quentin, Denost, Rodrigo O, Perez, Tsuyoshi, Konishi, Yves, Pani, Martin, Rutegård, Roel, Hompe, Camiel, Rosman, Frans, van Workum, Pieter J, Tani, Wilt, De, H W, Johanne, A Bremers, Andreas J, T Ferenschild, Flori, de Vriendt, Stefanie, D'Hoore, André, Bislenghi, Gabriele, Farguell, Jordi, M Lacy, Antonio, González Atienza, Paula, S van Kessel, Charlotte, Parc, Yann, Voron, Thibault, K Collard, Maxime, Sancho Muriel, Jorge, Cholewa, Hannia, A Mattioni, Laura, Frontali, Alice, W Polle, Sebastiaan, Polat, Fatih, J Obihara, Ndidi, B Vailati, Bruna, Kusters, Miranda, B Tuynmann, Jurriaan, A Hazen, Sanne J, J Grüter, Alexander A, Amano, Takahiro, Fujiwara, Hajime, Salomon, Mario, Ruiz, Hernán, Gonzalez, Ricardo, Estefanía, Diego, Avellaneda, Nicola, Carrie, Augusto, Santillan, Mateo, A Pantoja Pachajoa, Diana, Parodi, Matia, Gielis, Manuel, Binder, Alf-Dorian, Gürtler, Thoma, Riedl, Peter, Badiani, Sarit, Berney, Christophe, Morgan, Matthew, Hollington, Paul, da Silva, Nigel, Nair, Gavin, M Ho, Yiu, Lamparelli, Michael, Kapadia, Raj, M Kroon, Hidde, N Dudi-Venkata, Nagendra, Liu, Jianliang, Sammour, Tarik, Flamey, Nicola, Pattyn, Paul, Chaoui, Ahmed, Vansteenbrugge, Loui, J van den Broek, Nathalie E, Vanclooster, Patrick, de Gheldere, Charle, Pletinckx, Pieter, Defoort, Barbara, Dewulf, Maxime, Slavchev, Mihail, Belev, Nikolay, Atanasov, Boyko, Krastev, Panche, Sokolov, Manol, Maslyankov, Svilen, Gribnev, Petar, Pavlov, Vasil, Ivanov, Tsvetomir, Karamanliev, Martin, Filipov, Emil, Tonchev, Pencho, Aigner, Felix, Mitteregger, Martin, Allmer, Caterina, Seitinger, Gerald, Colucci, Nicola, Buchs, Nicola, Ris, Frédéric, Toso, Christian, Gialamas, Eleftherio, Vuagniaux, Aurélie, Chautems, Roland, Sauvain, Marc-Olivier, Daester, Silvio, von Flüe, Marku, Guenin, Marc-Olivier, Taha-Mehlitz, Stephanie, F Hess, Gabriel, Martínek, Lubomír, Skrovina, Matej, Machackova, Maria, Benčurik, Vladimir, Uluk, Deniz, Pratschke, Johann, S Dittrich, Luca, Guel-Klein, Safak, Perez, Daniel, Grass, Julia-Kristin, Melling, Nathaniel, Mueller, Simone, H Iversen, Lene, D Eriksen, Jacob, Baatrup, Gunnar, Al-Najami, Issam, Bjørsum-Meyer, Thoma, Teras, Jüri, M Teras, Roland, A Monib, Fatma, Eldin Abu Elnga Ahmed, Nagm, Alkady, Eithar, K Ali, Ahmed, Abd Elatti Khedr, Gehan, Samir Abdelaal, Ahmed, M Bassyouni Ashoush, Fouad, Ewedah, Moataz, M Elshennawy, Eslam, Hussein, Mohamed, Fernández-Martínez, Daniel, J García-Flórez, Lui, Fernández-Hevia, María, Suárez-Sánchez, Aida, Del Hoyo Aretxabala, Izaskun, Losada Docampo, Iria, Gómez Zabala, Jesú, Tejedor, Patricia, T Morales Bernaldo de Quirós, Javier, Bodega Quiroga, Ignacio, Navarro-Sánchez, Antonio, Soto Darias, Iván, López Fernández, Cristina, de La Cruz Cuadrado, Cristina, Sánchez-Guillén, Lui, López-Rodríguez-Arias, Francisco, Soler-Silva, Álvaro, Arroyo, Antonio, C Bernal-Sprekelsen, Juan, Á Gómez-Abril, Segundo, Gonzálvez, Paula, T Torres, María, Rubio Sánchez, Teresa, Blanco Antona, Francisco, E Sánchez Lara, Juan, A Alcázar Montero, José, Colás-Ruiz, Enrique, M Tasende-Presedo, Marta, Fernández-Hurtado, Ignacio, A Cifuentes-Ródenas, José, Castro Suárez, Marta, Losada, Manuel, Hernández, Miguel, Alonso, Alfredo, Diéguez, Beatriz, Serralta, Daniel, E Medina Quintana, Rita, M Gil Lopez, Jose, Lima Pinto, Francisca, Nieto-Moreno, Elena, Correa Bonito, Alba, Cerdán Santacruz, Carlo, Bermejo Marcos, Elena, García Septiem, Javier, Calero-Lillo, Aránzazu, Alanez-Saavedra, Javier, Muñoz-Collado, Salvador, López-Lara, Manuel, Labalde Martínez, María, Ferrero Herrero, Eduardo, Javier García Borda, Francisco, García Villar, Óscar, Escartín, Jorge, L Blas, Juan, Ferrer, Rocío, García Egea, Jorge, Rodríguez-Infante, Antonio, Mínguez-Ruiz, Germán, Carreño-Villarreal, Guillermo, Pire-Abaitua, Gerardo, Dziakova, Jana, 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Nicolò, Oldani, Massimo, Nespoli, Luca, Picciariello, Arcangelo, F Altomare, Donato, Tomasicchio, Giovanni, Lantone, Giuliano, Catena, Fausto, Giuffrida, Mario, Annicchiarico, Alfredo, Perrone, Gennaro, Grossi, Ugo, A Santoro, Giulio, Zanus, Giacomo, Iacomino, Alessandro, Novello, Simone, Passuello, Nicola, Zucchella, Martino, Puca, Lucia, Degiuli, Maurizio, Reddavid, Rossella, Scabini, Stefano, Aprile, Alessandra, Soriero, Domenico, Fioravanti, Emanuela, Rottoli, Matteo, Romano, Angela, Tanzanu, Marta, Belvedere, Angela, M Mariani, Nicolò, P Ceretti, Andrea, Opocher, Enrico, Gallo, Gaetano, Sammarco, Giuseppe, de Paola, Gilda, Pucciarelli, Salvatore, Marchegiani, Francesco, Spolverato, Gaya, Buzzi, Gianluca, Di Saverio, Salomone, Meroni, Paola, Parise, Cristiano, I Bottazzoli, Elisa, Lapolla, Pierfrancesco, Brachini, Gioia, Cirillo, Bruno, Mingoli, Andrea, Sica, Giuseppe, Siragusa, Leandro, Bellato, Vittoria, Cerbo, Daniele, A de Pasqual, Carlo, de Manzoni, Giovanni, A di Cosmo, 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Ahmet, Can Sari, Ahmet, Demirli Atici, Semra, Kaya, Tayfun, Dursun, Ayberk, Calik, Bulent, Faruk Özkan, Ömer, Şeyda Ülgür, Hanife, Düzgün, Özgül, Monson, John, George, Sarah, Woods, Kayla, Al-Eryani, Fatima, Albakry, Rudaina, Coetzee, Emile, Boutall, Adam, Herman, Ayesiga, Warden, Claire, Mugla, Naser, Forgan, Tim, Mia, Imraan, Lambrechts, Anton, Roberto Persiani (ORCID:0000-0002-1537-5097), Alberto Biondi (ORCID:0000-0002-2470-7858), Nynke G, Greijdanu, Kiedo, Wienholt, Sander, Ubel, Kevin, Talboom, Gerjon, Hannink, Albert, Wolthui, Francisco B, de Lacy, Jérémie H, Lefevre, Michael, Solomon, Matteo, Frasson, Nicolas, Rotholtz, Quentin, Denost, Rodrigo O, Perez, Tsuyoshi, Konishi, Yves, Pani, Martin, Rutegård, Roel, Hompe, Camiel, Rosman, Frans, van Workum, Pieter J, Tani, Wilt, De, H W, Johanne, A Bremers, Andreas J, T Ferenschild, Flori, de Vriendt, Stefanie, D'Hoore, André, Bislenghi, Gabriele, Farguell, Jordi, M Lacy, Antonio, González Atienza, Paula, S van Kessel, Charlotte, Parc, 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Bermejo Marcos, Elena, García Septiem, Javier, Calero-Lillo, Aránzazu, Alanez-Saavedra, Javier, Muñoz-Collado, Salvador, López-Lara, Manuel, Labalde Martínez, María, Ferrero Herrero, Eduardo, Javier García Borda, Francisco, García Villar, Óscar, Escartín, Jorge, L Blas, Juan, Ferrer, Rocío, García Egea, Jorge, Rodríguez-Infante, Antonio, Mínguez-Ruiz, Germán, Carreño-Villarreal, Guillermo, Pire-Abaitua, Gerardo, Dziakova, Jana, Sáez-Cazallas Rodríguez, Carlo, J Pizarro Aranda, María, M Muguerza Huguet, José, Borda-Arrizabalaga, Nerea, M Enriquez-Navascués, José, Elorza Echaniz, Garazi, Saralegui Ansorena, Yolanda, Estaire-Gómez, Mercede, Martínez-Pinedo, Carlo, Barbero-Valenzuela, Alejandro, Ruíz-García, Pablo, Kraft, Miquel, J Gómez-Jurado, María, Pellino, Gianluca, Espín-Basany, Eloy, Cotte, Eddy, Panel, Nathalie, Goutard, Claire-Angéline, Deángelis, Nicola, Lauka, Lelde, Shaikh, Shafaque, Osborne, Laura, Ramsay, George, Nichita, Vladimir-Ion, Bhandari, Santosh, Sarmah, Panchali, M Bethune, Rob, M Pringle, Heather C, Massey, Lisa, E Fowler, George, S Hamid, Hytham K, D de Simone, Belinda, Kynaston, Jame, Bradley, Nichola, M Stienstra, Roxane, Gurjar, Shashank, Mukherjee, Tanmoy, Chandio, Ashfaq, Ahmed, Safia, Singh, Baljit, Runau, Francoi, Chaudhri, Sanjay, Siaw, Oliver, Sarveswaran, Janahan, Miu, Victor, Ashmore, Daniel, Darwich, Haitham, Singh-Ranger, Deepak, Singh, Nirbhaibir, Shaban, Mohamed, Gareb, Fahed, Petropolou, Thalia, Polydorou, Adrea, Dattani, Mit, Afzal, Asma, Bavikatte, Akshay, Sebastian, Boby, Ward, Nichola, Mishra, Amitabh, Manatakis, Dimitrio, Agalianos, Christo, Tasis, Nikolao, Antonopoulou, Maria-Ioanna, Karavokyros, Ioanni, Charalabopoulos, Alexandro, Schizas, Dimitrio, Baili, Efstratia, Syllaios, Athanasio, Karydakis, Lysandro, Vailas, Michail, Balalis, Dimitrio, Korkolis, Dimitrio, Plastiras, Ari, Rompou, Aliki, Xenaki, Sofia, Xynos, Evangelo, Chrysos, Emmanuel, Venianaki, Maria, Christodoulidis, Grigorio, Perivoliotis, Konstantino, Tzovaras, George, Baloyiannis, Ioanni, Ho, Man-Fung, Siu-Man Ng, Simon, Wing-Chung Mak, Tony, Futaba, Kaori, Šantak, Goran, Šimleša, Damir, Osić, Jurica, Zukanović, Goran, E Kelly, Michael, O Larkin, John, H McCormick, Paul, J Mehigan, Brian, M Connelly, Tara, Neary, Peter, Ryan, Jessica, Mccullough, Peter, A Al-Juaifari, Maytham, Hammoodi, Hayder, Hashim Abbood, Ali, Calabrò, Marcello, Muratore, Andrea, La Terra, Antonio, Farnesi, Francesca, V Feo, Carlo, Fabbri, Nicolò, Pesce, Antonio, Fazzin, Marta, Roscio, Francesco, Clerici, Federico, Lucchi, Andrea, Vittori, Laura, Agostinelli, Laura, Cristina Ripoli, Maria, Sambucci, Daniele, Porta, Andrea, Sinibaldi, Giovanni, Crescentini, Giacomo, Larcinese, Antonella, Picone, Emanuele, Persiani, Roberto, Biondi, Alberto, Pezzuto, Roberto, Lorenzon, Laura, Rizzo, Gianluca, Coco, Claudio, D'Agostino, Luca, Spinelli, Antonino, M Sacchi, Matteo, Carvello, Michele, Foppa, Caterina, Maroli, Annalisa, M Palini, Gian, Garulli, Gianluca, Zanini, Nicola, Delrio, Paolo, Rega, Daniela, Carbone, Fabio, Aversano, Alessia, Pirozzolo, Giovanni, Recordare, Alfonso, D'Alimonte, Lucrezia, Vignotto, Chiara, Corbellini, Carlo, M Sampietro, Gianluca, Lorusso, Leonardo, A Manzo, Carlo, Ghignone, Federico, Ugolini, Giampaolo, Montroni, Isacco, Pasini, Franceso, Pasini, Francesco, Ballabio, Michele, Bisagni, Pietro, T Armao, Francesca, Longhi, Marco, Ghazouani, Omar, Galleano, Raffaele, Tamini, Nicolò, Oldani, Massimo, Nespoli, Luca, Picciariello, Arcangelo, F Altomare, Donato, Tomasicchio, Giovanni, Lantone, Giuliano, Catena, Fausto, Giuffrida, Mario, Annicchiarico, Alfredo, Perrone, Gennaro, Grossi, Ugo, A Santoro, Giulio, Zanus, Giacomo, Iacomino, Alessandro, Novello, Simone, Passuello, Nicola, Zucchella, Martino, Puca, Lucia, Degiuli, Maurizio, Reddavid, Rossella, Scabini, Stefano, Aprile, Alessandra, Soriero, Domenico, Fioravanti, Emanuela, Rottoli, Matteo, Romano, Angela, Tanzanu, Marta, Belvedere, Angela, M Mariani, Nicolò, P Ceretti, Andrea, Opocher, Enrico, Gallo, Gaetano, Sammarco, Giuseppe, de Paola, Gilda, Pucciarelli, Salvatore, Marchegiani, Francesco, Spolverato, Gaya, Buzzi, Gianluca, Di Saverio, Salomone, Meroni, Paola, Parise, Cristiano, I Bottazzoli, Elisa, Lapolla, Pierfrancesco, Brachini, Gioia, Cirillo, Bruno, Mingoli, Andrea, Sica, Giuseppe, Siragusa, Leandro, Bellato, Vittoria, Cerbo, Daniele, A de Pasqual, Carlo, de Manzoni, Giovanni, A di Cosmo, Maria, H Alrayes, Bourhan M, M Qandeel, Mahmoud W, Bani Hani, Mohammad, Rabadi, Alexander, S El Muhtaseb, Mohammad, Abdeen, Basel, Karmi, Fahed, Žilinskas, Justa, Latkauskas, Tada, Tamelis, Algimanta, Pikūnienė, Ingrida, Šlenfuktas, Vyginta, Poskus, Toma, Kryzauskas, Mariu, Jakubauskas, Mata, Mikalauskas, Sauliu, Jakubauskiene, Lina, Y Hassan, Soha, Altrabulsi, Amani, Abdulwahed, Eman, Ghmagh, Reem, Deeknah, Abdulqudu, Alshareea, Entisar, Elhadi, Muhammed, Abujamra, Saleh, A Msherghi, Ahmed, E Tababa, Osama W, A Majbar, Mohammed, Souadka, Amine, Benkabbou, Amine, Mohsine, Raouf, Echiguer, Sabrillah, Moctezuma-Velázquez, Paulina, Salgado-Nesme, Noel, Vergara-Fernández, Omar, C Sainz-Hernández, Juan, E Alvarez-Bautista, Francisco, D Zakaria, Andee, Zakaria, Zaidi, K Wong, Michael P, Ismail, Razif, F Ibrahim, Aini, N Abdullah, Nik A, Julaihi, Rokayah, Bhat, Sameer, O'Grady, Greg, Bissett, Ian, Lamme, Ba, D Musters, Gijsbert, M Dinaux, Anne, A Grotenhuis, Brechtje, J Aalbers, Ernst J Steller Arend G, M Leeuwenburgh, Marjolein, T Rutten, Harm J, A Burger, Jacobus W, G Bloemen, Johanne, J Ketelaers, Stijn H, Waqar, Usama, Chawla, Tabish, Rauf, Hareem, Rani, Pallavi, K Talsma, Aaldert, Scheurink, Lieke, B van Praagh, Jasper, Segelman, Josefin, Nygren, Jona, Anderin, Kajsa, Tiefenthal, Marit, de Andrés, Beatriz, P Beltrán de Heredia, Juan, Vázquez, Andrea, Gómez, Tania, Golshani, Parisa, Kader, Rawaz, Mohamed, Abudi, Westerterp, Marinke, Marinelli, Andrea, Niemer, Quirine, G Doornebosch, Pascal, Shapiro, Joël, Vermaas, Maarten, R de Graaf, Eelco J, L van Westreenen, Hendrik, Zwakman, Marije, D van Dalsen, Annette, J Vles, Wouter, Nonner, Joost, R Toorenvliet, Boudewijn, J Janssen, Paul T, G Verdaasdonk, Emiel G, J Amelung, Femke, R Bahadoer, Koen C M J Peeters Renu, A Holman, Fabian, Heemskerk, Jeroen, Vosbeek, Noortje, A Leijtens, Jeroen W, M Taverne, Sophie B, M Heijnen, Bob H, El-Massoudi, Youssef, de Groot-van Veen, Irene, Hoff, Christiaan, Jou-Valencia, Daniela, J Consten, Esther C, A Burghgraef, Thij, Geitenbeek, Ritch, L Hulshof, Lorenzo G W, D Slooter, Gerrit, Reudink, Muriël, D Bouvy, Nicole, L Wildeboer, Aurelia C, Verstappen, Sonja, J Pennings, Alexander, van den Hengel, Berber, G Wijma, Allard, de Haan, Jael, F de Nes, Lindsey C, Heesink, Vera, Karsten, Tom, M Heidsma, Charlotte, J Koemans, Willem, T Dekker, Jan-Willem, J van der Zijden, Charlène, Roos, Daphne, Demirkiran, Ahmet, van der Burg, Sjirk, J Oosterling, Steven, J Hoogteijling, Tij, Wiering, Bastiaan, J Smeeing, Diederik P, Havenga, Klaa, Lutfi, Hamid, Tsimogiannis, Konstantino, Sköldberg, Filip, Folkesson, Joakim, den Boer, Frank, G van Schaik, Ted, van Gerven, Pieter, Sietses, Colin, C Hol, Jeroen, G Boerma, Evert-Jan, J Creemers, Davy M, K Schultz, Johanne, Frivold, Tone, Riis, Rolf, Gregussen, Hilde, Busund, Sondre, H Sjo, Ole, Gaard, Maria, Krohn, Nina, L Ersryd, Amanda, Leung, Edmund, Sultan, Hytham, Nabil Hajjaj, Baraa, Jehad Alhisi, Ahmed, E Khader, Ahmed A, Filipa Dias Mendes, Ana, Semião, Miguel, Queiroz Faria, Lui, Azevedo, Constança, M da Costa Devesa, Helena, Fortuna Martins, Sónia, M Rodrigues Jarimba, Aldo, M Ribeiro Marques, Sónia, Marques Ferreira, Rita, Oliveira, António, Ferreira, Cátia, Pereira, Ricardo, M Surlin, Valeriu, M Graure, Giorgiana, D Ramboiu, Stefan Patrascu Sandu, Negoi, Ionut, Ciubotaru, Cezar, Stoica, Bogdan, Tanase, Ioan, M Negoita, Valentina, Florea, Sabrina, Macau, Florin, Vasile, Mihai, Stefanescu, Victor, Dimofte, Gabriel-Mihail, Luncă, Sorinel, Roată, Cristian-Ene, Mușină, Ana-Maria, Garmanova, Tatiana, N Agapov, Mikhail, G Markaryan, Daniil, Eduard, Galliamov, Yanishev, Alexey, Abelevich, Alexander, Bazaev, Andrey, V Rodimov, Sergey, B Filimonov, Victor, A Melnikov, Andrey, A Suchkov, Igor, Drozdov, Evgeniy, N Kostromitskiy, Dmitriy, Sjöström, Olle, Matthiessen, Peter, Baban, Bayar, Gadan, Soran, Dehlaghi Jadid, Kaveh, Staffan, Maria, M Park, Jennifer, Rydbeck, Daniel, Lydrup, Marie-Louise, Buchwald, Pamela, Jutesten, Henrik, Darlin, Lotten, Lindqvist, Ebba, Nilsson, Karl, Larsson, Per-Ander, Jangmalm, Staffan, A Košir, Jurij, Tomažič, Aleš, Grosek, Jan, Košir Božič, Tajda, Zazo, Aya, Zazo, Rama, Fares, Hala, Ayoub, Kusay, Niazi, Ammar, Mansour, Ali, Abbas, Ayman, Tantoura, Mohammad, Hamdan, Alaa, Hassan, Naya, Hasan, Bassam, Saad, Ahmad, Sebai, Amine, Haddad, Ani, Maghrebi, Houcine, Kacem, Montasser, Yalkın, Ömer, Veysi Samsa, Mehmet, Atak, İbrahim, Balci, Bengi, Haberal, Elifcan, Dogan, Lütfi, E Gecim, Ibrahim, Akyol, Cihangir, A Koc, Mehmet, Sivrikoz, Emre, Piyadeoğlu, Deniz, O Avanagh, Dara, Sökmen, Selman, Bişgin, Tayfun, Günenç, Erşan, Güzel, Melek, Leventoğlu, Sezai, Yüksel, Osman, Kozan, Ramazan, Göbüt, Hüseyin, Cengiz, Fevzi, Erdinc, Kemal, Coşgun Acar, Nihan, Kamer, Erdinc, Özgür, İlker, Aydın, Oguzhan, Keskin, Metin, Türker Bulut, Mehmet, B Kulle, Cemil, Kara, Yasin, Sıbıç, Osman, H Özata, İbrahim, Buğra, Dursun, Balık, Emre, Çakır, Murat, Alhardan, Ana, Colak, Elif, B CiftciEngin Aybar, Ahmet, Can Sari, Ahmet, Demirli Atici, Semra, Kaya, Tayfun, Dursun, Ayberk, Calik, Bulent, Faruk Özkan, Ömer, Şeyda Ülgür, Hanife, Düzgün, Özgül, Monson, John, George, Sarah, Woods, Kayla, Al-Eryani, Fatima, Albakry, Rudaina, Coetzee, Emile, Boutall, Adam, Herman, Ayesiga, Warden, Claire, Mugla, Naser, Forgan, Tim, Mia, Imraan, Lambrechts, Anton, Roberto Persiani (ORCID:0000-0002-1537-5097), and Alberto Biondi (ORCID:0000-0002-2470-7858)

Abstract

Objective:To develop and validate a prediction model (STOMA score) for 1-year stoma-free survival in patients with rectal cancer (RC) with anastomotic leakage (AL).Background:AL after RC resection often results in a permanent stoma.Methods:This international retrospective cohort study (TENTACLE-Rectum) encompassed 216 participating centres and included patients who developed AL after RC surgery between 2014 and 2018. Clinically relevant predictors for 1-year stoma-free survival were included in uni and multivariable logistic regression models. The STOMA score was developed and internally validated in a cohort of patients operated between 2014 and 2017, with subsequent temporal validation in a 2018 cohort. The discriminative power and calibration of the models' performance were evaluated.Results:This study included 2499 patients with AL, 1954 in the development cohort and 545 in the validation cohort. Baseline characteristics were comparable. One-year stoma-free survival was 45.0% in the development cohort and 43.7% in the validation cohort. The following predictors were included in the STOMA score: sex, age, American Society of Anestesiologist classification, body mass index, clinical M-disease, neoadjuvant therapy, abdominal and transanal approach, primary defunctioning stoma, multivisceral resection, clinical setting in which AL was diagnosed, postoperative day of AL diagnosis, abdominal contamination, anastomotic defect circumference, bowel wall ischemia, anastomotic fistula, retraction, and reactivation leakage. The STOMA score showed good discrimination and calibration (c-index: 0.71, 95% CI: 0.66-0.76).Conclusions:The STOMA score consists of 18 clinically relevant factors and estimates the individual risk for 1-year stoma-free survival in patients with AL after RC surgery, which may improve patient counseling and give guidance when analyzing the efficacy of different treatment strategies in future studies.

Published
2023

31. Stoma-free survival after anastomotic leak following rectal cancer resection: worldwide cohort of 2470 patients

Author

Nynke G, Greijdanu, Kiedo, Wienholt, Sander, Ubel, Kevin, Talboom, Gerjon, Hannink, Albert, Wolthui, F Borja, de Lacy, Jérémie H, Lefevre, Michael, Solomon, Matteo, Frasson, Nicolas, Rotholtz, Quentin, Denost, Rodrigo O, Perez, Tsuyoshi, Konishi, Yves, Pani, Martin, Rutegård, Roel, Hompe, Camiel, Rosman, Frans, van Workum, Pieter J, Tani, Johannes H W, de Wilt, A Bremers, Andreas J, T Ferenschild, Flori, de Vriendt, Stefanie, D'Hoore, André, Bislenghi, Gabriele, Farguell, Jordi, M Lacy, Antonio, González Atienza, Paula, S van Kessel, Charlotte, Parc, Yann, Voron, Thibault, K Collard, Maxime, Sancho Muriel, Jorge, Cholewa, Hannia, A Mattioni, Laura, Frontali, Alice, W Polle, Sebastiaan, Polat, Fatih, J Obihara, Ndidi, B Vailati, Bruna, Kusters, Miranda, B Tuynmann, Jurriaan, A Hazen, Sanne J, J Grüter, Alexander A, Amano, Takahiro, Fujiwara, Hajime, Salomon, Mario, Ruiz, Hernán, Gonzalez, Ricardo, Estefanía, Diego, Avellaneda, Nicola, Carrie, Augusto, Santillan, Mateo, A Pantoja Pachajoa, Diana, Parodi, Matia, Gielis, Manuel, Binder, Alf-Dorian, Gürtler, Thoma, Riedl, Peter, Badiani, Sarit, Berney, Christophe, Morgan, Matthew, Hollington, Paul, da Silva, Nigel, Nair, Gavin, M Ho, Yiu, Lamparelli, Michael, Kapadia, Raj, M Kroon, Hidde, N Dudi-Venkata, Nagendra, Liu, Jianliang, Sammour, Tarik, Flamey, Nicola, Pattyn, Paul, Chaoui, Ahmed, Vansteenbrugge, Loui, J van den Broek, Nathalie E, Vanclooster, Patrick, de Gheldere, Charle, Pletinckx, Pieter, Defoort, Barbara, Dewulf, Maxime, Slavchev, Mihail, Belev, Nikolay, Atanasov, Boyko, Krastev, Panche, Sokolov, Manol, Maslyankov, Svilen, Gribnev, Petar, Pavlov, Vasil, Ivanov, Tsvetomir, Karamanliev, Martin, Filipov, Emil, Tonchev, Pencho, Aigner, Felix, Mitteregger, Martin, Allmer, Caterina, Seitinger, Gerald, Colucci, Nicola, Buchs, Nicola, Ris, Frédéric, Toso, Christian, Gialamas, Eleftherio, Vuagniaux, Aurélie, Chautems, Roland, Sauvain, Marc-Olivier, Daester, Silvio, von Flüe, Marku, Guenin, Marc-Olivier, Taha-Mehlitz, Stephanie, F Hess, Gabriel, Martínek, Lubomír, Skrovina, Matej, Machackova, Maria, Benčurik, Vladimir, Uluk, Deniz, Pratschke, Johann, S Dittrich, Luca, Guel-Klein, Safak, Perez, Daniel, Grass, Julia-Kristin, Melling, Nathaniel, Mueller, Simone, H Iversen, Lene, D Eriksen, Jacob, Baatrup, Gunnar, Al-Najami, Issam, Bjørsum-Meyer, Thoma, Teras, Jüri, M Teras, Roland, A Monib, Fatma, Eldin Abu Elnga Ahmed, Nagm, Alkady, Eithar, K Ali, Ahmed, Abd Elatti Khedr, Gehan, Samir Abdelaal, Ahmed, M Bassyouni Ashoush, Fouad, Ewedah, Moataz, M Elshennawy, Eslam, Hussein, Mohamed, Fernández-Martínez, Daniel, J García-Flórez, Lui, Fernández-Hevia, María, Suárez-Sánchez, Aida, Del Hoyo Aretxabala, Izaskun, Losada Docampo, Iria, Gómez Zabala, Jesú, Tejedor, Patricia, T Morales Bernaldo de Quirós, Javier, Bodega Quiroga, Ignacio, Navarro-Sánchez, Antonio, Soto Darias, Iván, López Fernández, Cristina, de La Cruz Cuadrado, Cristina, Sánchez-Guillén, Lui, López-Rodríguez-Arias, Francisco, Soler-Silva, Álvaro, Arroyo, Antonio, C Bernal-Sprekelsen, Juan, Á Gómez-Abril, Segundo, Gonzálvez, Paula, T Torres, María, Rubio Sánchez, Teresa, Blanco Antona, Francisco, E Sánchez Lara, Juan, A Alcázar Montero, José, Mendoza-Moreno, Fernando, Díez-Alonso, Manuel, Matías-García, Belén, Quiroga-Valcárcel, Ana, Colás-Ruiz, Enrique, M Tasende-Presedo, Marta, Fernández-Hurtado, Ignacio, A Cifuentes-Ródenas, José, Castro Suárez, Marta, Losada, Manuel, Hernández, Miguel, Alonso, Alfredo, Diéguez, Beatriz, Serralta, Daniel, E Medina Quintana, Rita, M Gil Lopez, Jose, Lima Pinto, Francisca, Nieto-Moreno, Elena, Correa Bonito, Alba, Cerdán Santacruz, Carlo, Bermejo Marcos, Elena, García Septiem, Javier, Calero-Lillo, Aránzazu, Alanez-Saavedra, Javier, Muñoz-Collado, Salvador, López-Lara, Manuel, Labalde Martínez, María, Ferrero Herrero, Eduardo, Javier García Borda, Francisco, García Villar, Óscar, Escartín, Jorge, L Blas, Juan, Ferrer, Rocío, García Egea, Jorge, Rodríguez-Infante, Antonio, 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Daniel, Darwich, Haitham, Singh-Ranger, Deepak, Singh, Nirbhaibir, Shaban, Mohamed, Gareb, Fahed, Petropolou, Thalia, Polydorou, Adrea, Dattani, Mit, Afzal, Asma, Bavikatte, Akshay, Sebastian, Boby, Ward, Nichola, Mishra, Amitabh, Manatakis, Dimitrio, Agalianos Nikolaos Tasis, Christo, Antonopoulou, Maria-Ioanna, Karavokyros, Ioanni, Charalabopoulos, Alexandro, Schizas, Dimitrio, Baili, Efstratia, Syllaios, Athanasio, Karydakis, Lysandro, Vailas, Michail, Balalis, Dimitrio, Korkolis, Dimitrio, Plastiras, Ari, Rompou, Aliki, Xenaki, Sofia, Xynos, Evangelo, Chrysos, Emmanuel, Venianaki, Maria, Christodoulidis, Grigorio, Perivoliotis, Konstantino, Tzovaras, George, Baloyiannis, Ioanni, Ho, Man-Fung, Siu-Man Ng, Simon, Wing-Chung Mak, Tony, Futaba, Kaori, Šantak, Goran, Šimleša, Damir, Ćosić, Jurica, Zukanović, Goran, E Kelly, Michael, O Larkin, John, H McCormick, Paul, J Mehigan, Brian, M Connelly, Tara, Neary, Peter, Ryan, Jessica, Mccullough, Peter, A Al-Juaifari, Maytham, Hammoodi, Hayder, Hashim Abbood, Ali, Calabrò, Marcello, Muratore, Andrea, La Terra, Antonio, Farnesi, Francesca, V Feo, Carlo, Fabbri, Nicolò, Pesce, Antonio, Fazzin, Marta, Roscio, Francesco, Clerici, Federico, Lucchi, Andrea, Vittori, Laura, Agostinelli, Laura, Cristina Ripoli, Maria, Sambucci, Daniele, Porta, Andrea, Sinibaldi, Giovanni, Crescentini, Giacomo, Larcinese, Antonella, Picone, Emanuele, Persiani, Roberto, Biondi, Alberto, Pezzuto, Roberto, Lorenzon, Laura, Rizzo, Gianluca, Coco, Claudio, D'Agostino, Luca, Spinelli, Antonino, M Sacchi, Matteo, Carvello, Michele, Foppa, Caterina, Maroli, Annalisa, M Palini, Gian, Garulli, Gianluca, Zanini, Nicola, Delrio, Paolo, Rega, Daniela, Carbone, Fabio, Aversano, Alessia, Pirozzolo, Giovanni, Recordare, Alfonso, D'Alimonte, Lucrezia, Vignotto, Chiara, Corbellini, Carlo, M Sampietro, Gianluca, Lorusso, Leonardo, A Manzo, Carlo, Ghignone, Federico, Ugolini, Giampaolo, Montroni, Isacco, Pasini, Franceso, Pasini, Francesco, Ballabio, Michele, Bisagni, Pietro, T Armao, Francesca, Longhi, Marco, Ghazouani, Omar, Galleano, Raffaele, Tamini, Nicolò, Oldani, Massimo, Nespoli, Luca, Picciariello, Arcangelo, F Altomare, Donato, Tomasicchio, Giovanni, Lantone, Giuliano, Catena, Fausto, Giuffrida, Mario, Annicchiarico, Alfredo, Perrone, Gennaro, Grossi, Ugo, A Santoro, Giulio, Zanus Alessandro Iacomino, Giacomo, Novello, Simone, Passuello, Nicola, Zucchella, Martino, Puca, Lucia, Degiuli, Maurizio, Reddavid, Rossella, Scabini, Stefano, Aprile, Alessandra, Soriero, Domenico, Fioravanti, Emanuela, Rottoli, Matteo, Romano, Angela, Tanzanu, Marta, Belvedere, Angela, M Mariani, Nicolò, P Ceretti, Andrea, Opocher, Enrico, Gallo, Gaetano, Sammarco, Giuseppe, de Paola, Gilda, Pucciarelli, Salvatore, Marchegiani, Francesco, Spolverato, Gaya, Buzzi, Gianluca, Di Saverio, Salomone, Meroni, Paola, Parise, Cristiano, I Bottazzoli, Elisa, Lapolla, Pierfrancesco, Brachini, Gioia, Cirillo, Bruno, Mingoli, Andrea, Sica, Giuseppe, Siragusa, Leandro, Bellato, Vittoria, Cerbo, Daniele, A de Pasqual, Carlo, de Manzoni, Giovanni, A di Cosmo, Maria, H Alrayes, Bourhan M, M Qandeel, Mahmoud W, Bani Hani, Mohammad, Rabadi, Alexander, S El Muhtaseb, Mohammad, Abdeen, Basel, Karmi, Fahed, Žilinskas, Justa, Latkauskas, Tada, Tamelis, Algimanta, Pikūnienė, Ingrida, Šlenfuktas, Vyginta, Poskus, Toma, Kryzauskas, Mariu, Jakubauskas, Mata, Mikalauskas, Sauliu, Jakubauskiene, Lina, Y Hassan, Soha, Altrabulsi, Amani, Abdulwahed, Eman, Ghmagh, Reem, Deeknah, Abdulqudu, Alshareea, Entisar, Elhadi, Muhammed, Abujamra, Saleh, A Msherghi, Ahmed, E Tababa, Osama W, A Majbar, Mohammed, Souadka, Amine, Benkabbou, Amine, Mohsine, Raouf, Echiguer, Sabrillah, Moctezuma-Velázquez, Paulina, Salgado-Nesme, Noel, Vergara-Fernández, Omar, C Sainz-Hernández, Juan, E Alvarez-Bautista, Francisco, D Zakaria, Andee, Zakaria, Zaidi, K Wong, Michael P, Ismail, Razif, F Ibrahim, Aini, N Abdullah, Nik A, Julaihi, Rokayah, Bhat, Sameer, O'Grady, Greg, Bissett, Ian, Lamme, Ba, D Musters, Gijsbert, M Dinaux, Anne, A Grotenhuis, Brechtje, J Aalbers, Ernst J Steller Arend G, M Leeuwenburgh, Marjolein, T Rutten, Harm J, A Burger, Jacobus W, G Bloemen, Johanne, J Ketelaers, Stijn H, Waqar, Usama, Chawla, Tabish, Rauf, Hareem, Rani, Pallavi, K Talsma, Aaldert, Scheurink, Lieke, B van Praagh, Jasper, Segelman, Josefin, Nygren, Jona, Anderin, Kajsa, Tiefenthal, Marit, de Andrés, Beatriz, P Beltrán de Heredia, Juan, Vázquez, Andrea, Gómez, Tania, Golshani, Parisa, Kader, Rawaz, Mohamed, Abudi, Westerterp, Marinke, Marinelli, Andrea, Niemer, Quirine, G Doornebosch, Pascal, Shapiro, Joël, Vermaas, Maarten, R de Graaf, Eelco J, L van Westreenen, Hendrik, Zwakman, Marije, D van Dalsen, Annette, J Vles, Wouter, Nonner, Joost, R Toorenvliet, Boudewijn, J Janssen, Paul T, G Verdaasdonk, Emiel G, J Amelung, Femke, R Bahadoer, Koen C M J Peeters Renu, A Holman, Fabian, Heemskerk, Jeroen, Vosbeek, Noortje, A Leijtens, Jeroen W, M Taverne, Sophie B, M Heijnen, Bob H, El-Massoudi, Youssef, de Groot-van Veen, Irene, Hoff, Christiaan, Jou-Valencia, Daniela, A Burghgraef, Esther C J Consten Thij, Geitenbeek, Ritch, L Hulshof, Lorenzo G W, D Slooter, Gerrit, Reudink, Muriël, D Bouvy, Nicole, L Wildeboer, Aurelia C, Verstappen, Sonja, J Pennings, Alexander, van den Hengel, Berber, G Wijma, Allard, de Haan, Jael, F de Nes, Lindsey C, Heesink, Vera, Karsten, Tom, M Heidsma, Charlotte, J Koemans, Willem, T Dekker, Jan-Willem, J van der Zijden, Charlène, Roos, Daphne, Demirkiran, Ahmet, van der Burg, Sjirk, J Oosterling, Steven, J Hoogteijling, Tij, Wiering, Bastiaan, J Smeeing, Diederik P, Havenga, Klaa, Lutfi, Hamid, J Consten, Esther C, Tsimogiannis, Konstantino, Sköldberg, Filip, Folkesson, Joakim, den Boer, Frank, G van Schaik, Ted, van Gerven, Pieter, Sietses, Colin, C Hol, Jeroen, G Boerma, Evert-Jan, J Creemers, Davy M, K Schultz, Johanne, Frivold, Tone, Riis, Rolf, Gregussen, Hilde, Busund, Sondre, H Sjo, Ole, Gaard, Maria, Krohn, Nina, L Ersryd, Amanda, Leung, Edmund, Sultan, Hytham, Nabil Hajjaj, Baraa, Jehad Alhisi, Ahmed, E Khader, Ahmed A, Filipa Dias Mendes, Ana, Semião, Miguel, Queiroz Faria, Lui, Azevedo, Constança, M da Costa Devesa, Helena, Fortuna Martins, Sónia, M Rodrigues Jarimba, Aldo, M Ribeiro Marques, Sónia, Marques Ferreira, Rita, Oliveira, António, Ferreira, Cátia, Pereira, Ricardo, M Surlin, Valeriu, M Graure, Giorgiana, D Ramboiu, Stefan Patrascu Sandu, Negoi, Ionut, Ciubotaru, Cezar, Stoica, Bogdan, Tanase, Ioan, M Negoita, Valentina, Florea, Sabrina, Macau, Florin, Vasile, Mihai, Stefanescu, Victor, Dimofte, Gabriel-Mihail, Luncă, Sorinel, Roată, Cristian-Ene, Mușină, Ana-Maria, Garmanova, Tatiana, N Agapov, Mikhail, G Markaryan, Daniil, Eduard, Galliamov, Yanishev, Alexey, Abelevich, Alexander, Bazaev, Andrey, V Rodimov, Sergey, B Filimonov, Victor, A Melnikov, Andrey, A Suchkov, Igor, S Drozdov, Evgeniy, N Kostromitskiy, Dmitriy, Sjöström, Olle, Matthiessen, Peter, Baban, Bayar, Gadan, Soran, Dehlaghi Jadid, Kaveh, Staffan, Maria, M Park, Jennifer, Rydbeck, Daniel, Lydrup, Marie-Louise, Buchwald, Pamela, Jutesten, Henrik, Darlin, Lotten, Lindqvist, Ebba, Nilsson, Karl, Larsson, Per-Ander, Jangmalm, Staffan, A Košir, Jurij, Tomažič, Aleš, Grosek, Jan, Košir Božič, Tajda, Zazo, Aya, Zazo, Rama, Fares, Hala, Ayoub, Kusay, Niazi, Ammar, Mansour, Ali, Abbas, Ayman, Tantoura, Mohammad, Hamdan, Alaa, Hassan, Naya, Hasan, Bassam, Saad, Ahmad, Sebai, Amine, Haddad, Ani, Maghrebi, Houcine, Kacem, Montasser, Yalkın, Ömer, Veysi Samsa, Mehmet, Atak, İbrahim, Balci, Bengi, Haberal, Elifcan, Dogan, Lütfi, E Gecim, Ibrahim, Akyol, Cihangir, A Koc, Mehmet, Sivrikoz, Emre, Piyadeoğlu, Deniz, O Avanagh, Dara, Sökmen, Selman, Bişgin, Tayfun, Günenç, Erşan, Güzel, Melek, Leventoğlu, Sezai, Yüksel, Osman, Kozan, Ramazan, Göbüt, Hüseyin, Cengiz, Fevzi, Erdinc, Kemal, Coşgun Acar, Nihan, Kamer, Erdinc, Özgür, İlker, Aydın, Oguzhan, Keskin, Metin, Türker Bulut, Mehmet, B Kulle, Cemil, Kara, Yasin, Sıbıç, Osman, H Özata, İbrahim, Buğra, Dursun, Balık, Emre, Çakır, Murat, Alhardan, Ana, Colak, Elif, B CiftciEngin Aybar, Ahmet, Can Sari, Ahmet, Demirli Atici, Semra, Kaya, Tayfun, Dursun, Ayberk, Calik, Bulent, Faruk Özkan, Ömer, Şeyda Ülgür, Hanife, Düzgün, Özgül, Monson, John, George, Sarah, Woods, Kayla, Al-Eryani, Fatima, Albakry, Rudaina, Coetzee, Emile, Boutall, Adam, Herman, Ayesiga, Warden, Claire, Mugla, Naser, Forgan, Tim, Mia, Imraan, Lambrechts, Anton, Roberto Persiani (ORCID:0000-0002-1537-5097), Alberto Biondi (ORCID:0000-0002-2470-7858), Roberto Pezzuto, Laura Lorenzon (ORCID:0000-0001-6736-0383), Gianluca Rizzo, Claudio Coco (ORCID:0000-0002-4713-7093), Nynke G, Greijdanu, Kiedo, Wienholt, Sander, Ubel, Kevin, Talboom, Gerjon, Hannink, Albert, Wolthui, F Borja, de Lacy, Jérémie H, Lefevre, Michael, Solomon, Matteo, Frasson, Nicolas, Rotholtz, Quentin, Denost, Rodrigo O, Perez, Tsuyoshi, Konishi, Yves, Pani, Martin, Rutegård, Roel, Hompe, Camiel, Rosman, Frans, van Workum, Pieter J, Tani, Johannes H W, de Wilt, A Bremers, Andreas J, T Ferenschild, Flori, de Vriendt, Stefanie, D'Hoore, André, Bislenghi, Gabriele, Farguell, Jordi, M Lacy, Antonio, González Atienza, Paula, S van Kessel, Charlotte, Parc, Yann, Voron, Thibault, K Collard, Maxime, Sancho Muriel, Jorge, Cholewa, Hannia, A Mattioni, Laura, Frontali, Alice, W Polle, Sebastiaan, Polat, Fatih, J Obihara, Ndidi, B Vailati, Bruna, Kusters, Miranda, B Tuynmann, Jurriaan, A Hazen, Sanne J, J Grüter, Alexander A, Amano, Takahiro, Fujiwara, Hajime, Salomon, Mario, Ruiz, Hernán, Gonzalez, Ricardo, Estefanía, Diego, Avellaneda, Nicola, Carrie, Augusto, Santillan, Mateo, A Pantoja Pachajoa, Diana, Parodi, Matia, Gielis, Manuel, Binder, Alf-Dorian, Gürtler, Thoma, Riedl, Peter, Badiani, Sarit, Berney, Christophe, Morgan, Matthew, Hollington, Paul, da Silva, Nigel, Nair, Gavin, M Ho, Yiu, Lamparelli, Michael, Kapadia, Raj, M Kroon, Hidde, N Dudi-Venkata, Nagendra, Liu, Jianliang, Sammour, Tarik, Flamey, Nicola, Pattyn, Paul, Chaoui, Ahmed, Vansteenbrugge, Loui, J van den Broek, Nathalie E, Vanclooster, Patrick, de Gheldere, Charle, Pletinckx, Pieter, Defoort, Barbara, Dewulf, Maxime, Slavchev, Mihail, Belev, Nikolay, Atanasov, Boyko, Krastev, Panche, Sokolov, Manol, Maslyankov, Svilen, Gribnev, Petar, Pavlov, Vasil, Ivanov, Tsvetomir, Karamanliev, Martin, Filipov, Emil, Tonchev, Pencho, Aigner, Felix, Mitteregger, Martin, Allmer, Caterina, Seitinger, Gerald, Colucci, Nicola, Buchs, Nicola, Ris, Frédéric, Toso, Christian, Gialamas, Eleftherio, Vuagniaux, Aurélie, Chautems, Roland, Sauvain, Marc-Olivier, Daester, Silvio, von Flüe, Marku, Guenin, Marc-Olivier, Taha-Mehlitz, Stephanie, F Hess, Gabriel, Martínek, Lubomír, Skrovina, Matej, Machackova, Maria, Benčurik, Vladimir, Uluk, Deniz, Pratschke, Johann, S Dittrich, Luca, Guel-Klein, Safak, Perez, Daniel, Grass, Julia-Kristin, Melling, Nathaniel, Mueller, Simone, H Iversen, Lene, D Eriksen, Jacob, Baatrup, Gunnar, Al-Najami, Issam, Bjørsum-Meyer, Thoma, Teras, Jüri, M Teras, Roland, A Monib, Fatma, Eldin Abu Elnga Ahmed, Nagm, Alkady, Eithar, K Ali, Ahmed, Abd Elatti Khedr, Gehan, Samir Abdelaal, Ahmed, M Bassyouni Ashoush, Fouad, Ewedah, Moataz, M Elshennawy, Eslam, Hussein, Mohamed, Fernández-Martínez, Daniel, J García-Flórez, Lui, Fernández-Hevia, María, Suárez-Sánchez, Aida, Del Hoyo Aretxabala, Izaskun, Losada Docampo, Iria, Gómez Zabala, Jesú, Tejedor, Patricia, T Morales Bernaldo de Quirós, Javier, Bodega Quiroga, Ignacio, Navarro-Sánchez, Antonio, Soto Darias, Iván, López Fernández, Cristina, de La Cruz Cuadrado, Cristina, Sánchez-Guillén, Lui, López-Rodríguez-Arias, Francisco, Soler-Silva, Álvaro, Arroyo, Antonio, C Bernal-Sprekelsen, Juan, Á Gómez-Abril, Segundo, Gonzálvez, Paula, T Torres, María, Rubio Sánchez, Teresa, Blanco Antona, Francisco, E Sánchez Lara, Juan, A Alcázar Montero, José, Mendoza-Moreno, Fernando, Díez-Alonso, Manuel, Matías-García, Belén, Quiroga-Valcárcel, Ana, Colás-Ruiz, Enrique, M Tasende-Presedo, Marta, Fernández-Hurtado, Ignacio, A Cifuentes-Ródenas, José, Castro Suárez, Marta, Losada, Manuel, Hernández, Miguel, Alonso, Alfredo, Diéguez, Beatriz, Serralta, Daniel, E Medina Quintana, Rita, M Gil Lopez, Jose, Lima Pinto, Francisca, Nieto-Moreno, Elena, Correa Bonito, Alba, Cerdán Santacruz, Carlo, Bermejo Marcos, Elena, García Septiem, Javier, Calero-Lillo, Aránzazu, Alanez-Saavedra, Javier, Muñoz-Collado, Salvador, López-Lara, Manuel, Labalde Martínez, María, Ferrero Herrero, Eduardo, Javier García Borda, Francisco, García Villar, Óscar, Escartín, Jorge, L Blas, Juan, Ferrer, Rocío, García Egea, Jorge, Rodríguez-Infante, Antonio, Mínguez-Ruiz, Germán, Carreño-Villarreal, Guillermo, Pire-Abaitua, Gerardo, Dziakova, Jana, Sáez-Cazallas Rodríguez, Carlo, J Pizarro Aranda, María, M Muguerza Huguet, José, Borda-Arrizabalaga, Nerea, M Enriquez-Navascués, José, Elorza Echaniz, Garazi, Saralegui Ansorena, Yolanda, Estaire-Gómez, Mercede, Martínez-Pinedo, Carlo, Barbero-Valenzuela, Alejandro, Ruíz-García, Pablo, Kraft, Miquel, J Gómez-Jurado, María, Pellino, Gianluca, Espín-Basany, Eloy, Cotte, Eddy, Panel, Nathalie, Goutard, Claire-Angéline, Deángelis, Nicola, Lauka, Lelde, Shaikh, Shafaque, Osborne, Laura, Ramsay, George, Nichita, Vladimir-Ion, Bhandari, Santosh, Sarmah, Panchali, M Bethune, Rob, M Pringle, Heather C, Massey, Lisa, E Fowler, George, S Hamid, Hytham K, D de Simone, Belinda, Kynaston, Jame, Bradley, Nichola, M Stienstra, Roxane, Gurjar, Shashank, Mukherjee, Tanmoy, Chandio, Ashfaq, Ahmed, Safia, Singh, Baljit, Runau, Francoi, Chaudhri, Sanjay, Siaw, Oliver, Sarveswaran, Janahan, Miu, Victor, Ashmore, Daniel, Darwich, Haitham, Singh-Ranger, Deepak, Singh, Nirbhaibir, Shaban, Mohamed, Gareb, Fahed, Petropolou, Thalia, Polydorou, Adrea, Dattani, Mit, Afzal, Asma, Bavikatte, Akshay, Sebastian, Boby, Ward, Nichola, Mishra, Amitabh, Manatakis, Dimitrio, Agalianos Nikolaos Tasis, Christo, Antonopoulou, Maria-Ioanna, Karavokyros, Ioanni, Charalabopoulos, Alexandro, Schizas, Dimitrio, Baili, Efstratia, Syllaios, Athanasio, Karydakis, Lysandro, Vailas, Michail, Balalis, Dimitrio, Korkolis, Dimitrio, Plastiras, Ari, Rompou, Aliki, Xenaki, Sofia, Xynos, Evangelo, Chrysos, Emmanuel, Venianaki, Maria, Christodoulidis, Grigorio, Perivoliotis, Konstantino, Tzovaras, George, Baloyiannis, Ioanni, Ho, Man-Fung, Siu-Man Ng, Simon, Wing-Chung Mak, Tony, Futaba, Kaori, Šantak, Goran, Šimleša, Damir, Ćosić, Jurica, Zukanović, Goran, E Kelly, Michael, O Larkin, John, H McCormick, Paul, J Mehigan, Brian, M Connelly, Tara, Neary, Peter, Ryan, Jessica, Mccullough, Peter, A Al-Juaifari, Maytham, Hammoodi, Hayder, Hashim Abbood, Ali, Calabrò, Marcello, Muratore, Andrea, La Terra, Antonio, Farnesi, Francesca, V Feo, Carlo, Fabbri, Nicolò, Pesce, Antonio, Fazzin, Marta, Roscio, Francesco, Clerici, Federico, Lucchi, Andrea, Vittori, Laura, Agostinelli, Laura, Cristina Ripoli, Maria, Sambucci, Daniele, Porta, Andrea, Sinibaldi, Giovanni, Crescentini, Giacomo, Larcinese, Antonella, Picone, Emanuele, Persiani, Roberto, Biondi, Alberto, Pezzuto, Roberto, Lorenzon, Laura, Rizzo, Gianluca, Coco, Claudio, D'Agostino, Luca, Spinelli, Antonino, M Sacchi, Matteo, Carvello, Michele, Foppa, Caterina, Maroli, Annalisa, M Palini, Gian, Garulli, Gianluca, Zanini, Nicola, Delrio, Paolo, Rega, Daniela, Carbone, Fabio, Aversano, Alessia, Pirozzolo, Giovanni, Recordare, Alfonso, D'Alimonte, Lucrezia, Vignotto, Chiara, Corbellini, Carlo, M Sampietro, Gianluca, Lorusso, Leonardo, A Manzo, Carlo, Ghignone, Federico, Ugolini, Giampaolo, Montroni, Isacco, Pasini, Franceso, Pasini, Francesco, Ballabio, Michele, Bisagni, Pietro, T Armao, Francesca, Longhi, Marco, Ghazouani, Omar, Galleano, Raffaele, Tamini, Nicolò, Oldani, Massimo, Nespoli, Luca, Picciariello, Arcangelo, F Altomare, Donato, Tomasicchio, Giovanni, Lantone, Giuliano, Catena, Fausto, Giuffrida, Mario, Annicchiarico, Alfredo, Perrone, Gennaro, Grossi, Ugo, A Santoro, Giulio, Zanus Alessandro Iacomino, Giacomo, Novello, Simone, Passuello, Nicola, Zucchella, Martino, Puca, Lucia, Degiuli, Maurizio, Reddavid, Rossella, Scabini, Stefano, Aprile, Alessandra, Soriero, Domenico, Fioravanti, Emanuela, Rottoli, Matteo, Romano, Angela, Tanzanu, Marta, Belvedere, Angela, M Mariani, Nicolò, P Ceretti, Andrea, Opocher, Enrico, Gallo, Gaetano, Sammarco, Giuseppe, de Paola, Gilda, Pucciarelli, Salvatore, Marchegiani, Francesco, Spolverato, Gaya, Buzzi, Gianluca, Di Saverio, Salomone, Meroni, Paola, Parise, Cristiano, I Bottazzoli, Elisa, Lapolla, Pierfrancesco, Brachini, Gioia, Cirillo, Bruno, Mingoli, Andrea, Sica, Giuseppe, Siragusa, Leandro, Bellato, Vittoria, Cerbo, Daniele, A de Pasqual, Carlo, de Manzoni, Giovanni, A di Cosmo, Maria, H Alrayes, Bourhan M, M Qandeel, Mahmoud W, Bani Hani, Mohammad, Rabadi, Alexander, S El Muhtaseb, Mohammad, Abdeen, Basel, Karmi, Fahed, Žilinskas, Justa, Latkauskas, Tada, Tamelis, Algimanta, Pikūnienė, Ingrida, Šlenfuktas, Vyginta, Poskus, Toma, Kryzauskas, Mariu, Jakubauskas, Mata, Mikalauskas, Sauliu, Jakubauskiene, Lina, Y Hassan, Soha, Altrabulsi, Amani, Abdulwahed, Eman, Ghmagh, Reem, Deeknah, Abdulqudu, Alshareea, Entisar, Elhadi, Muhammed, Abujamra, Saleh, A Msherghi, Ahmed, E Tababa, Osama W, A Majbar, Mohammed, Souadka, Amine, Benkabbou, Amine, Mohsine, Raouf, Echiguer, Sabrillah, Moctezuma-Velázquez, Paulina, Salgado-Nesme, Noel, Vergara-Fernández, Omar, C Sainz-Hernández, Juan, E Alvarez-Bautista, Francisco, D Zakaria, Andee, Zakaria, Zaidi, K Wong, Michael P, Ismail, Razif, F Ibrahim, Aini, N Abdullah, Nik A, Julaihi, Rokayah, Bhat, Sameer, O'Grady, Greg, Bissett, Ian, Lamme, Ba, D Musters, Gijsbert, M Dinaux, Anne, A Grotenhuis, Brechtje, J Aalbers, Ernst J Steller Arend G, M Leeuwenburgh, Marjolein, T Rutten, Harm J, A Burger, Jacobus W, G Bloemen, Johanne, J Ketelaers, Stijn H, Waqar, Usama, Chawla, Tabish, Rauf, Hareem, Rani, Pallavi, K Talsma, Aaldert, Scheurink, Lieke, B van Praagh, Jasper, Segelman, Josefin, Nygren, Jona, Anderin, Kajsa, Tiefenthal, Marit, de Andrés, Beatriz, P Beltrán de Heredia, Juan, Vázquez, Andrea, Gómez, Tania, Golshani, Parisa, Kader, Rawaz, Mohamed, Abudi, Westerterp, Marinke, Marinelli, Andrea, Niemer, Quirine, G Doornebosch, Pascal, Shapiro, Joël, Vermaas, Maarten, R de Graaf, Eelco J, L van Westreenen, Hendrik, Zwakman, Marije, D van Dalsen, Annette, J Vles, Wouter, Nonner, Joost, R Toorenvliet, Boudewijn, J Janssen, Paul T, G Verdaasdonk, Emiel G, J Amelung, Femke, R Bahadoer, Koen C M J Peeters Renu, A Holman, Fabian, Heemskerk, Jeroen, Vosbeek, Noortje, A Leijtens, Jeroen W, M Taverne, Sophie B, M Heijnen, Bob H, El-Massoudi, Youssef, de Groot-van Veen, Irene, Hoff, Christiaan, Jou-Valencia, Daniela, A Burghgraef, Esther C J Consten Thij, Geitenbeek, Ritch, L Hulshof, Lorenzo G W, D Slooter, Gerrit, Reudink, Muriël, D Bouvy, Nicole, L Wildeboer, Aurelia C, Verstappen, Sonja, J Pennings, Alexander, van den Hengel, Berber, G Wijma, Allard, de Haan, Jael, F de Nes, Lindsey C, Heesink, Vera, Karsten, Tom, M Heidsma, Charlotte, J Koemans, Willem, T Dekker, Jan-Willem, J van der Zijden, Charlène, Roos, Daphne, Demirkiran, Ahmet, van der Burg, Sjirk, J Oosterling, Steven, J Hoogteijling, Tij, Wiering, Bastiaan, J Smeeing, Diederik P, Havenga, Klaa, Lutfi, Hamid, J Consten, Esther C, Tsimogiannis, Konstantino, Sköldberg, Filip, Folkesson, Joakim, den Boer, Frank, G van Schaik, Ted, van Gerven, Pieter, Sietses, Colin, C Hol, Jeroen, G Boerma, Evert-Jan, J Creemers, Davy M, K Schultz, Johanne, Frivold, Tone, Riis, Rolf, Gregussen, Hilde, Busund, Sondre, H Sjo, Ole, Gaard, Maria, Krohn, Nina, L Ersryd, Amanda, Leung, Edmund, Sultan, Hytham, Nabil Hajjaj, Baraa, Jehad Alhisi, Ahmed, E Khader, Ahmed A, Filipa Dias Mendes, Ana, Semião, Miguel, Queiroz Faria, Lui, Azevedo, Constança, M da Costa Devesa, Helena, Fortuna Martins, Sónia, M Rodrigues Jarimba, Aldo, M Ribeiro Marques, Sónia, Marques Ferreira, Rita, Oliveira, António, Ferreira, Cátia, Pereira, Ricardo, M Surlin, Valeriu, M Graure, Giorgiana, D Ramboiu, Stefan Patrascu Sandu, Negoi, Ionut, Ciubotaru, Cezar, Stoica, Bogdan, Tanase, Ioan, M Negoita, Valentina, Florea, Sabrina, Macau, Florin, Vasile, Mihai, Stefanescu, Victor, Dimofte, Gabriel-Mihail, Luncă, Sorinel, Roată, Cristian-Ene, Mușină, Ana-Maria, Garmanova, Tatiana, N Agapov, Mikhail, G Markaryan, Daniil, Eduard, Galliamov, Yanishev, Alexey, Abelevich, Alexander, Bazaev, Andrey, V Rodimov, Sergey, B Filimonov, Victor, A Melnikov, Andrey, A Suchkov, Igor, S Drozdov, Evgeniy, N Kostromitskiy, Dmitriy, Sjöström, Olle, Matthiessen, Peter, Baban, Bayar, Gadan, Soran, Dehlaghi Jadid, Kaveh, Staffan, Maria, M Park, Jennifer, Rydbeck, Daniel, Lydrup, Marie-Louise, Buchwald, Pamela, Jutesten, Henrik, Darlin, Lotten, Lindqvist, Ebba, Nilsson, Karl, Larsson, Per-Ander, Jangmalm, Staffan, A Košir, Jurij, Tomažič, Aleš, Grosek, Jan, Košir Božič, Tajda, Zazo, Aya, Zazo, Rama, Fares, Hala, Ayoub, Kusay, Niazi, Ammar, Mansour, Ali, Abbas, Ayman, Tantoura, Mohammad, Hamdan, Alaa, Hassan, Naya, Hasan, Bassam, Saad, Ahmad, Sebai, Amine, Haddad, Ani, Maghrebi, Houcine, Kacem, Montasser, Yalkın, Ömer, Veysi Samsa, Mehmet, Atak, İbrahim, Balci, Bengi, Haberal, Elifcan, Dogan, Lütfi, E Gecim, Ibrahim, Akyol, Cihangir, A Koc, Mehmet, Sivrikoz, Emre, Piyadeoğlu, Deniz, O Avanagh, Dara, Sökmen, Selman, Bişgin, Tayfun, Günenç, Erşan, Güzel, Melek, Leventoğlu, Sezai, Yüksel, Osman, Kozan, Ramazan, Göbüt, Hüseyin, Cengiz, Fevzi, Erdinc, Kemal, Coşgun Acar, Nihan, Kamer, Erdinc, Özgür, İlker, Aydın, Oguzhan, Keskin, Metin, Türker Bulut, Mehmet, B Kulle, Cemil, Kara, Yasin, Sıbıç, Osman, H Özata, İbrahim, Buğra, Dursun, Balık, Emre, Çakır, Murat, Alhardan, Ana, Colak, Elif, B CiftciEngin Aybar, Ahmet, Can Sari, Ahmet, Demirli Atici, Semra, Kaya, Tayfun, Dursun, Ayberk, Calik, Bulent, Faruk Özkan, Ömer, Şeyda Ülgür, Hanife, Düzgün, Özgül, Monson, John, George, Sarah, Woods, Kayla, Al-Eryani, Fatima, Albakry, Rudaina, Coetzee, Emile, Boutall, Adam, Herman, Ayesiga, Warden, Claire, Mugla, Naser, Forgan, Tim, Mia, Imraan, Lambrechts, Anton, Roberto Persiani (ORCID:0000-0002-1537-5097), Alberto Biondi (ORCID:0000-0002-2470-7858), Roberto Pezzuto, Laura Lorenzon (ORCID:0000-0001-6736-0383), Gianluca Rizzo, and Claudio Coco (ORCID:0000-0002-4713-7093)

Abstract

Background The optimal treatment of anastomotic leak after rectal cancer resection is unclear. This worldwide cohort study aimed to provide an overview of four treatment strategies applied.Methods Patients from 216 centres and 45 countries with anastomotic leak after rectal cancer resection between 2014 and 2018 were included. Treatment was categorized as salvage surgery, faecal diversion with passive or active (vacuum) drainage, and no primary/secondary faecal diversion. The primary outcome was 1-year stoma-free survival. In addition, passive and active drainage were compared using propensity score matching (2 : 1).Results Of 2470 evaluable patients, 388 (16.0 per cent) underwent salvage surgery, 1524 (62.0 per cent) passive drainage, 278 (11.0 per cent) active drainage, and 280 (11.0 per cent) had no faecal diversion. One-year stoma-free survival rates were 13.7, 48.3, 48.2, and 65.4 per cent respectively. Propensity score matching resulted in 556 patients with passive and 278 with active drainage. There was no statistically significant difference between these groups in 1-year stoma-free survival (OR 0.95, 95 per cent c.i. 0.66 to 1.33), with a risk difference of -1.1 (95 per cent c.i. -9.0 to 7.0) per cent. After active drainage, more patients required secondary salvage surgery (OR 2.32, 1.49 to 3.59), prolonged hospital admission (an additional 6 (95 per cent c.i. 2 to 10) days), and ICU admission (OR 1.41, 1.02 to 1.94). Mean duration of leak healing did not differ significantly (an additional 12 (-28 to 52) days).Conclusion Primary salvage surgery or omission of faecal diversion likely correspond to the most severe and least severe leaks respectively. In patients with diverted leaks, stoma-free survival did not differ statistically between passive and active drainage, although the increased risk of secondary salvage surgery and ICU admission suggests residual confounding.The optimal treatment strategy for anastomotic leakage after restorative rectal cancer su

Published
2023

32. Treatment of anastomotic leak after oesophagectomy for oesophageal cancer:large, collaborative, observational TENTACLE cohort study

Author

Ubels, Sander, Verstegen, Moniek H.P., Klarenbeek, Bastiaan R., Bouwense, Stefan, Van Berge Henegouwen, Mark I., Daams, Freek, Van Det, Marc J., Griffiths, Ewen A., Haveman, Jan Willem, Heisterkamp, Joos, Nieuwenhuijzen, Grard, Polat, Fatih, Schouten, Jeroen, Siersema, Peter D., Singh, Pritam, Wijnhoven, Bas, Hannink, Gerjon, Van Workum, Frans, Rosman, Camiel, Ubels, Sander, Verstegen, Moniek H.P., Klarenbeek, Bastiaan R., Bouwense, Stefan, Van Berge Henegouwen, Mark I., Daams, Freek, Van Det, Marc J., Griffiths, Ewen A., Haveman, Jan Willem, Heisterkamp, Joos, Nieuwenhuijzen, Grard, Polat, Fatih, Schouten, Jeroen, Siersema, Peter D., Singh, Pritam, Wijnhoven, Bas, Hannink, Gerjon, Van Workum, Frans, and Rosman, Camiel

Abstract

Background: Anastomotic leak is a severe complication after oesophagectomy. Anastomotic leak has diverse clinical manifestations and the optimal treatment strategy is unknown. The aim of this study was to assess the efficacy of treatment strategies for different manifestations of anastomotic leak after oesophagectomy. Methods: A retrospective cohort study was performed in 71 centres worldwide and included patients with anastomotic leak after oesophagectomy (2011-2019). Different primary treatment strategies were compared for three different anastomotic leak manifestations: interventional versus supportive-only treatment for local manifestations (that is no intrathoracic collections; well perfused conduit); drainage and defect closure versus drainage only for intrathoracic manifestations; and oesophageal diversion versus continuity-preserving treatment for conduit ischaemia/necrosis. The primary outcome was 90-day mortality. Propensity score matching was performed to adjust for confounders. Results: Of 1508 patients with anastomotic leak, 28.2 per cent (425 patients) had local manifestations, 36.3 per cent (548 patients) had intrathoracic manifestations, 9.6 per cent (145 patients) had conduit ischaemia/necrosis, 17.5 per cent (264 patients) were allocated after multiple imputation, and 8.4 per cent (126 patients) were excluded. After propensity score matching, no statistically significant differences in 90-day mortality were found regarding interventional versus supportive-only treatment for local manifestations (risk difference 3.2 per cent, 95 per cent c.i. -1.8 to 8.2 per cent), drainage and defect closure versus drainage only for intrathoracic manifestations (risk difference 5.8 per cent, 95 per cent c.i. -1.2 to 12.8 per cent), and oesophageal diversion versus continuity-preserving treatment for conduit ischaemia/necrosis (risk difference 0.1 per cent, 95 per cent c.i. -21.4 to 1.6 per cent). In general, less morbidity was found after less extensive primary

Published
2023

33. Trends in Distal Esophageal and Gastroesophageal Junction Cancer Care: The Dutch Nationwide Ivory Study

Author

MS CGO, Cancer, Externen Med. Onco, Kalff, Marianne C, Henegouwen, Mark I van Berge, Baas, Peter C, Bahadoer, Renu R, Belt, Eric J T, Brattinga, Baukje, Claassen, Linda, Ćosović, Admira, Crull, David, Daams, Freek, van Dalsen, Annette D, Dekker, Jan Willem T, van Det, Marc J, Drost, Manon, van Duijvendijk, Peter, Eshuis, Wietse J, van Esser, Stijn, Gaspersz, Marcia P, Görgec, Burak, Groenendijk, Richard P R, Hartgrink, Henk H, van der Harst, Erwin, Haveman, Jan Willem, Heisterkamp, Joos, van Hillegersberg, Richard, Kelder, Wendy, Kingma, B Feike, Koemans, Willem J, Kouwenhoven, Ewout A, Lagarde, Sjoerd M, Lecot, Frederik, van der Linden, Philip P, Luyer, Misha D P, Nieuwenhuijzen, Grard A P, Olthof, Pim B, van der Peet, Donald L, Pierie, Jean-Pierre E N, Pierik, E G J M Robert, Plat, Victor D, Polat, Fatih, Rosman, Camiel, Ruurda, Jelle P, van Sandick, Johanna W, Scheer, Rene, Slootmans, Cettela A M, Sosef, Meindert N, Sosef, Odin V, de Steur, Wobbe O, Stockmann, Hein B A C, Stoop, Fanny J, Voeten, Daan M, Vugts, Guusje, Vijgen, Guy H E J, Weeda, Víola B, Wiezer, Marinus J, van Oijen, Martijn G H, Gisbertz, Suzanne S, MS CGO, Cancer, Externen Med. Onco, Kalff, Marianne C, Henegouwen, Mark I van Berge, Baas, Peter C, Bahadoer, Renu R, Belt, Eric J T, Brattinga, Baukje, Claassen, Linda, Ćosović, Admira, Crull, David, Daams, Freek, van Dalsen, Annette D, Dekker, Jan Willem T, van Det, Marc J, Drost, Manon, van Duijvendijk, Peter, Eshuis, Wietse J, van Esser, Stijn, Gaspersz, Marcia P, Görgec, Burak, Groenendijk, Richard P R, Hartgrink, Henk H, van der Harst, Erwin, Haveman, Jan Willem, Heisterkamp, Joos, van Hillegersberg, Richard, Kelder, Wendy, Kingma, B Feike, Koemans, Willem J, Kouwenhoven, Ewout A, Lagarde, Sjoerd M, Lecot, Frederik, van der Linden, Philip P, Luyer, Misha D P, Nieuwenhuijzen, Grard A P, Olthof, Pim B, van der Peet, Donald L, Pierie, Jean-Pierre E N, Pierik, E G J M Robert, Plat, Victor D, Polat, Fatih, Rosman, Camiel, Ruurda, Jelle P, van Sandick, Johanna W, Scheer, Rene, Slootmans, Cettela A M, Sosef, Meindert N, Sosef, Odin V, de Steur, Wobbe O, Stockmann, Hein B A C, Stoop, Fanny J, Voeten, Daan M, Vugts, Guusje, Vijgen, Guy H E J, Weeda, Víola B, Wiezer, Marinus J, van Oijen, Martijn G H, and Gisbertz, Suzanne S

Published
2023

34. Comparison of three-year oncological results after restorative low anterior resection, non-restorative low anterior resection and abdominoperineal resection for rectal cancer

Author

Hol, Jeroen C., primary, Burghgraef, Thijs A., additional, Rutgers, Marieke L.W., additional, Crolla, Rogier M.P.H., additional, van Geloven, Nanette A.W., additional, Leijtens, Jeroen W.A., additional, Polat, Fatih, additional, Pronk, Apollo, additional, Smits, Anke B., additional, Tuynman, Jurriaan B., additional, Verdaasdonk, Emiel G.G., additional, Consten, Esther C.J., additional, Hompes, Roel, additional, and Sietses, Colin, additional

Published
2023
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35. Circulating tumor DNA detection after neoadjuvant treatment and surgery predicts recurrence in patients with early-stage and locally advanced rectal cancer

Author

Hofste, Lisa S.M., primary, Geerlings, Maartje J., additional, von Rhein, Daniel, additional, Rütten, Heidi, additional, Westenberg, A. Helen, additional, Weiss, Marjan M., additional, Gilissen, Christian, additional, Hofste, Tom, additional, van der Post, Rachel S., additional, Klarenbeek, Bastiaan R., additional, de Wilt, Johannes H.W., additional, Ligtenberg, Marjolijn J.L., additional, Garms, Linda, additional, Liem, Maite, additional, Rozema, Tom, additional, Wasowicz, Dareczka, additional, Burger, Pim, additional, Polat, Fatih, additional, Reijnders, Koen, additional, de Roos, Marnix, additional, and Sietses, Colin, additional

Published
2023
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36. Practice variation in anastomotic leak after esophagectomy: Unravelling differences in failure to rescue

Author

Ubels, Sander, primary, Matthée, Eric, additional, Verstegen, Moniek, additional, Klarenbeek, Bastiaan, additional, Bouwense, Stefan, additional, van Berge Henegouwen, Mark I., additional, Daams, Freek, additional, Dekker, Jan Willem T., additional, van Det, Marc J., additional, van Esser, Stijn, additional, Griffiths, Ewen A., additional, Haveman, Jan Willem, additional, Nieuwenhuijzen, Grard, additional, Siersema, Peter D., additional, Wijnhoven, Bas, additional, Hannink, Gerjon, additional, van Workum, Frans, additional, Rosman, Camiel, additional, Heisterkamp, Joos, additional, Polat, Fatih, additional, Schouten, Jeroen, additional, Singh, Pritam, additional, Slootmans, Cettela A.M., additional, Ultee, Gijs, additional, Gisbertz, Suzanne S., additional, Eshuis, Wietse J., additional, Kalff, Marianne C., additional, Feenstra, Minke L., additional, van der Peet, Donald L., additional, Stam, Wessel T., additional, Van Etten, Boudewijn, additional, Poelmann, Floris, additional, Vuurberg, Nienke, additional, Willem van den Berg, Jan, additional, Martijnse, Ingrid S., additional, Matthijsen, Robert M., additional, Luyer, Misha, additional, Curvers, Wout, additional, Nieuwenhuijzen, Tom, additional, Taselaar, Annick E., additional, Kouwenhoven, Ewout A., additional, Lubbers, Merel, additional, Sosef, Meindert, additional, Lecot, Frederik, additional, Geraedts, Tessa C.M., additional, van den Wildenberg, Frits, additional, Kelder, Wendy, additional, Baas, Peter C., additional, de Haas, Job W.A., additional, Hartgrink, Henk H., additional, Bahadoer, Renu R., additional, van Sandick, Johanna W., additional, Hartemink, Koen J., additional, Veenhof, Xander, additional, Stockmann, Hein, additional, Gorgec, Burak, additional, Weeder, Pepijn, additional, Wiezer, Marinus J., additional, Genders, Charlotte M.S., additional, Belt, Eric, additional, Blomberg, Bjorn, additional, van Duijvendijk, Peter, additional, Claassen, Linda, additional, Reetz, David, additional, Steenvoorde, Pascal, additional, Mastboom, Walter, additional, Klein Ganseij, Henk Jan, additional, van Dalsen, Annette D., additional, Joldersma, Annalie, additional, Zwakman, Marije, additional, Groenendijk, Richard P.R., additional, Montazeri, Mahsa, additional, Mercer, Stuart, additional, Knight, Benjamin, additional, van Boxel, Gijs, additional, McGregor, Richard J., additional, Skipworth, Richard J.E., additional, Frattini, Cristina, additional, Bradley, Alice, additional, Nilsson, Magnus, additional, Hayami, Masaru, additional, Huang, Biying, additional, Bundred, James, additional, Evans, Richard, additional, Grimminger, Peter P., additional, van der Sluis, Pieter C., additional, Eren, Uzun, additional, Saunders, John, additional, Theophilidou, Elena, additional, Khanzada, Zubair, additional, Elliott, Jessie A., additional, Ponten, Jeroen, additional, King, Sinead, additional, Reynolds, John V., additional, Sgromo, Bruno, additional, Akbari, Khalid, additional, Shalaby, Samar, additional, Gutschow, Christian A., additional, Schmidt, Henner, additional, Vetter, Diana, additional, Moorthy, Krishna, additional, Ibrahim, Mohamed A.H., additional, Christodoulidis, Grigorious, additional, Räsänen, Jari V., additional, Kauppi, Juha, additional, Söderström, Henna, additional, Koshy, Renol, additional, Manatakis, Dimitrios K., additional, Korkolis, Dimitrios P., additional, Balalis, Dimitrios, additional, Rompu, Aliki, additional, Alkhaffaf, Bilal, additional, Alasmar, Mohamed, additional, Arebi, Moaad, additional, Piessen, Guillaume, additional, Nuytens, Frederiek, additional, Degisors, Sebastien, additional, Ahmed, Ahmed, additional, Boddy, Alex, additional, Gandhi, Suraj, additional, Fashina, Oluwatomini, additional, Van Daele, Elke, additional, Pattyn, Piet, additional, Robb, William B., additional, Arumugasamy, Mayilone, additional, Al Azzawi, Mohammed, additional, Whooley, Jack, additional, Colak, Elif, additional, Aybar, Engin, additional, Sari, Ahmet C., additional, Uyanik, Mustafa S., additional, Ciftci, Ahmet B., additional, Sayyed, Raza, additional, Ayub, Bushra, additional, Murtaza, Ghulam, additional, Saeed, Aniqa, additional, Ramesh, Priyanka, additional, Charalabopoulos, Alexandros, additional, Liakakos, Theodore, additional, Schizas, Dimitrios, additional, Baili, Efstratia, additional, Kapelouzou, Alkistis, additional, Valmasoni, Michele, additional, Pierobon, Elisa Sefora, additional, Capovilla, Giovanni, additional, Merigliano, Stefano, additional, Constantinoiu, Silviu, additional, Birla, Rodica, additional, Achim, Florin, additional, Rosianu, Cristian Gelu, additional, Hoara, Petre, additional, Castro, Raúl Guevara, additional, Salcedo, Andrés Felipe, additional, Negoi, Ionut, additional, Negoita, Valentina M., additional, Ciubotaru, Cezar, additional, Stoica, Bogdan, additional, Hostiuc, Sorin, additional, Colucci, Nicola, additional, Mönig, Stefan P., additional, Wassmer, Charles-Henri, additional, Meyer, Jeremy, additional, Takeda, Flavio Roberto, additional, Aissar Sallum, Rubens Antonio, additional, Ribeiro, Ulysses, additional, Cecconello, Ivan, additional, Toledo, Enrique, additional, Trugeda, Maria Soledad, additional, Fernández, María José, additional, Gil, Carolina, additional, Castanedo, Sonia, additional, Isik, Arda, additional, Kurnaz, Eray, additional, Videira, José Flávio, additional, Peyroteo, Mariana, additional, Canotilho, Rita, additional, Weindelmayer, Jacopo, additional, Giacopuzzi, Simone, additional, De Pasqual, Carlo Alberto, additional, Bruna, Marcos, additional, Mingol, Fernando, additional, Vaque, Javier, additional, Pérez, Carla, additional, Phillips, Alexander W., additional, Chmelo, Jakub, additional, Brown, Joshua, additional, Han, Laura E., additional, Gossage, James A., additional, Davies, Andrew R., additional, Baker, Cara R., additional, Kelly, Mark, additional, Saad, Mohamed, additional, Bernardi, Daniele, additional, Bonavina, Luigi, additional, Asti, Emanuele, additional, Riva, Carlo, additional, Scaramuzzo, Rosa, additional, Elhadi, Muhammed, additional, Ahmed, Hazem Abdelkarem, additional, Elhadi, Ahmed, additional, Elnagar, Faruk Ali, additional, Msherghi, Ahmed A.A., additional, Wills, Vanessa, additional, Campbell, Cassidy, additional, Cerdeira, Marisol Perez, additional, Whiting, Scott, additional, Merrett, Neil, additional, Das, Amitabha, additional, Apostolou, Christos, additional, Lorenzo, Aldenb, additional, Sousa, Fabiana, additional, Barbosa, José Adelino, additional, Devezas, Vítor, additional, Barbosa, Elisabete, additional, Fernandes, Cristina, additional, Smith, Garett, additional, Li, Edward Y., additional, Bhimani, Nazim, additional, Chan, Priscilla, additional, Kotecha, Krishna, additional, Hii, Michael W., additional, Ward, Salena M., additional, Johnson, MaryAnn, additional, Read, Matthew, additional, Chong, Lynn, additional, Hollands, Michael J., additional, Allaway, Matthew, additional, Richardson, Arthur, additional, Johnston, Emma, additional, Chen, Andy Z.L., additional, Kanhere, Harsh, additional, Prasad, Shalvin, additional, McQuillan, Patrick, additional, Surman, Tim, additional, Trochsler, MarkusI., additional, Schofield, W.A., additional, Ahmed, Syeda Khadijah, additional, Reid, Jessica L., additional, Harris, Mark C., additional, Gananadha, Sivakumar, additional, Farrant, Jessica, additional, Rodrigues, Nicole, additional, Fergusson, James, additional, Hindmarsh, Andrew, additional, Afzal, Zeeshan, additional, Safranek, Peter, additional, Sujendran, Vijay, additional, Rooney, Siobhan, additional, Loureiro, Carlos, additional, Fernández, Saioa Leturio, additional, Díez del Val, Ismael, additional, Jaunoo, Shameen, additional, Kennedy, Lauren, additional, Hussain, Ahmed, additional, Theodorou, Dimitrios, additional, Triantafyllou, Tania, additional, Theodoropoulos, Charalampos, additional, Palyvou, Theodora, additional, Ben Taher, Fatima Abdullah, additional, and Ekheel, Mustafa, additional

Published
2023
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37. Impact of a diverting ileostomy in total mesorectal excision with primary anastomosis for rectal cancer

Author

Hol, Jeroen C., primary, Burghgraef, Thijs A., additional, Rutgers, Marieke L. W., additional, Crolla, Rogier M. P. H., additional, van Geloven, Anna A. W., additional, de Jong, Gabie M., additional, Hompes, Roel, additional, Leijtens, Jeroen W. A., additional, Polat, Fatih, additional, Pronk, Apollo, additional, Smits, Anke B., additional, Tuynman, Jurriaan B., additional, Verdaasdonk, Emiel G. G., additional, Consten, Esther C. J., additional, and Sietses, Colin, additional

Published
2022
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38. Treatment of anastomotic leak after oesophagectomy for oesophageal cancer: large, collaborative, observational TENTACLE cohort study.

Author

Ubels, Sander, Verstegen, Moniek H. P., Klarenbeek, Bastiaan R., Bouwense, Stefan, Henegouwen, Mark I. van Berge, Daams, Freek, van Det, Marc J., Griffiths, Ewen A., Haveman, Jan Willem, Heisterkamp, Joos, Nieuwenhuijzen, Grard, Polat, Fatih, Schouten, Jeroen, Siersema, Peter D., Singh, Pritam, Wijnhoven, Bas, Hannink, Gerjon, van Workum, Frans, and Rosman, Camiel

Subjects
ESOPHAGEAL cancer, ESOPHAGECTOMY, PROPENSITY score matching, COHORT analysis
Abstract

Background: Anastomotic leak is a severe complication after oesophagectomy. Anastomotic leak has diverse clinical manifestations and the optimal treatment strategy is unknown. The aim of this study was to assess the efficacy of treatment strategies for different manifestations of anastomotic leak after oesophagectomy. Methods: A retrospective cohort study was performed in 71 centres worldwide and included patients with anastomotic leak after oesophagectomy (2011-2019). Different primary treatment strategies were compared for three different anastomotic leak manifestations: interventional versus supportive-only treatment for local manifestations (that is no intrathoracic collections; well perfused conduit); drainage and defect closure versus drainage only for intrathoracic manifestations; and oesophageal diversion versus continuity-preserving treatment for conduit ischaemia/necrosis. The primary outcome was 90-day mortality. Propensity score matching was performed to adjust for confounders. Results: Of 1508 patients with anastomotic leak, 28.2 per cent (425 patients) had local manifestations, 36.3 per cent (548 patients) had intrathoracic manifestations, 9.6 per cent (145 patients) had conduit ischaemia/necrosis, 17.5 per cent (264 patients) were allocated after multiple imputation, and 8.4 per cent (126 patients) were excluded. After propensity score matching, no statistically significant differences in 90-day mortality were found regarding interventional versus supportive-only treatment for local manifestations (risk difference 3.2 per cent, 95 per cent c.i. -1.8 to 8.2 per cent), drainage and defect closure versus drainage only for intrathoracic manifestations (risk difference 5.8 per cent, 95 per cent c.i. -1.2 to 12.8 per cent), and oesophageal diversion versus continuity-preserving treatment for conduit ischaemia/necrosis (risk difference 0.1 per cent, 95 per cent c.i. -21.4 to 1.6 per cent). In general, less morbidity was found after less extensive primary treatment strategies. Conclusion: Less extensive primary treatment of anastomotic leak was associated with less morbidity. A less extensive primary treatment approach may potentially be considered for anastomotic leak. Future studies are needed to confirm current findings and guide optimal treatment of anastomotic leak after oesophagectomy. [ABSTRACT FROM AUTHOR]

Published
2023
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40. 186. RECURRENT DISEASE AFTER ESOPHAGEAL CANCER SURGERY; A SUBSTUDY OF THE DUTCH NATIONWIDE IVORY STUDY

Author

Henckens, Sofie, primary, Kalff, Marianne, additional, Voeten, Daan, additional, Heineman, David, additional, Hulshof, Maarten, additional, van Laarhoven, Hanneke, additional, Eshuis, Wietse, additional, Baas, Peter, additional, Bahadoer, Renu, additional, Belt, Eric, additional, Brattinga, Baukje, additional, Claassen, Linda, additional, Cosovic, Admira, additional, Crull, David, additional, Daams, Freek, additional, van Dalsen, Annette, additional, Dekker, Jan Willem, additional, van Det, Marc, additional, Drost, Manon, additional, van Duijvendijk, Peter, additional, van Esser, Stijn, additional, Gaspersz, Marcia, additional, Görgec, Burak, additional, Groenendijk, Richard, additional, Hartgrink, Henk, additional, van der Harst, Erwin, additional, Haveman, Jan Willem, additional, Heisterkamp, Joos, additional, van Hillegersberg, Richard, additional, Kelder, Wendy, additional, Kingma, Feike, additional, Koemans, Willem, additional, Kouwenhoven, Ewout, additional, Lagarde, Sjoerd, additional, Lecot, Frederik, additional, van der Linden, Philip, additional, Luyer, Misha, additional, Nieuwenhuijzen, Grard, additional, Olthof, Pim, additional, van der Peet, Donald, additional, Pierie, Jean-Pierre, additional, Pierik, Robert, additional, Plat, Victor, additional, Polat, Fatih, additional, Rosman, Camiel, additional, Ruurda, Jelle, additional, van Sandick, Johanna, additional, Scheer, Rene, additional, Slootmans, Cettela, additional, Sosef, Meindert, additional, Sosef, Odin, additional, de Steur, Wobbe, additional, Stockmann, Hein, additional, Stoop, Fanny, additional, Vugts, Guusje, additional, Vijgen, Guy, additional, Weeda, Viola, additional, Wiezer, Marinus, additional, van Ooijen, Martijn, additional, van Berge Henegouwen, Mark, additional, and Gisbertz, Suzanne, additional

Published
2022
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42. Functional Dyspepsia and Irritable Bowel Syndrome are Highly Prevalent in Patients With Gallstones and Are Negatively Associated With Outcomes After Cholecystectomy A Prospective, Multicenter, Observational Study (PERFECT-Trial)

Author

Jong, J.J. de, Latenstein, C.S.S., Boerma, Djamila, Hazebroek, Eric J., Hirsch, David, Heikens, Joost T., Polat, Fatih, Lantinga, M.A., Laarhoven, C.J.H.M. van, Drenth, J.P.H., Reuver, P.R. de, Jong, J.J. de, Latenstein, C.S.S., Boerma, Djamila, Hazebroek, Eric J., Hirsch, David, Heikens, Joost T., Polat, Fatih, Lantinga, M.A., Laarhoven, C.J.H.M. van, Drenth, J.P.H., and Reuver, P.R. de

Abstract

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Published
2022

43. Severity of oEsophageal Anastomotic Leak in patients after oesophagectomy: the SEAL score

Author

Ubels, S., Verstegen, M.H.P., Klarenbeek, B.R., Bouwense, S., Berge Henegouwen, M.I. van, Daams, F., Det, M.J. van, Griffiths, E.A., Haveman, J.W., Heisterkamp, J., Koshy, R., Nieuwenhuijzen, G., Polat, Fatih, Siersema, P.D., Singh, P., Wijnhoven, B., Hannink, G.J., Workum, F.T.W.E. van, Rosman, C., Ubels, S., Verstegen, M.H.P., Klarenbeek, B.R., Bouwense, S., Berge Henegouwen, M.I. van, Daams, F., Det, M.J. van, Griffiths, E.A., Haveman, J.W., Heisterkamp, J., Koshy, R., Nieuwenhuijzen, G., Polat, Fatih, Siersema, P.D., Singh, P., Wijnhoven, B., Hannink, G.J., Workum, F.T.W.E. van, and Rosman, C.

Abstract

Contains fulltext : 282376.pdf (Publisher’s version ) (Open Access), BACKGROUND: Anastomotic leak (AL) is a common but severe complication after oesophagectomy. It is unknown how to determine the severity of AL objectively at diagnosis. Determining leak severity may guide treatment decisions and improve future research. This study aimed to identify leak-related prognostic factors for mortality, and to develop a Severity of oEsophageal Anastomotic Leak (SEAL) score. METHODS: This international, retrospective cohort study in 71 centres worldwide included patients with AL after oesophagectomy between 2011 and 2019. The primary endpoint was 90-day mortality. Leak-related prognostic factors were identified after adjusting for confounders and were included in multivariable logistic regression to develop the SEAL score. Four classes of leak severity (mild, moderate, severe, and critical) were defined based on the risk of 90-day mortality, and the score was validated internally. RESULTS: Some 1509 patients with AL were included and the 90-day mortality rate was 11.7 per cent. Twelve leak-related prognostic factors were included in the SEAL score. The score showed good calibration and discrimination (c-index 0.77, 95 per cent c.i. 0.73 to 0.81). Higher classes of leak severity graded by the SEAL score were associated with a significant increase in duration of ICU stay, healing time, Comprehensive Complication Index score, and Esophagectomy Complications Consensus Group classification. CONCLUSION: The SEAL score grades leak severity into four classes by combining 12 leak-related predictors and can be used to the assess severity of AL after oesophagectomy.

Published
2022

44. European consensus on essential steps of Minimally Invasive Ivor Lewis and McKeown Esophagectomy through Delphi methodology

Author

Eddahchouri, Y., Workum, F.T.W.E. van, Wildenberg, F.J. van den, Berge Henegouwen, M.I. van, Polat, Fatih, Goor, H. van, Pierie, J.E.N., Klarenbeek, B.R., Gisbertz, S.S., Rosman, C., Eddahchouri, Y., Workum, F.T.W.E. van, Wildenberg, F.J. van den, Berge Henegouwen, M.I. van, Polat, Fatih, Goor, H. van, Pierie, J.E.N., Klarenbeek, B.R., Gisbertz, S.S., and Rosman, C.

Abstract

Contains fulltext : 251521.pdf (Publisher’s version ) (Open Access), BACKGROUND: Minimally invasive esophagectomy (MIE) is a complex and technically demanding procedure with a long learning curve, which is associated with increased morbidity and mortality. To master MIE, training in essential steps is crucial. Yet, no consensus on essential steps of MIE is available. The aim of this study was to achieve expert consensus on essential steps in Ivor Lewis and McKeown MIE through Delphi methodology. METHODS: Based on expert opinion and peer-reviewed literature, essential steps were defined for Ivor Lewis (IL) and McKeown (McK) MIE. In a round table discussion, experts finalized the lists of steps and an online Delphi questionnaire was sent to an international expert panel (7 European countries) of minimally invasive upper GI surgeons. Based on replies and comments, steps were adjusted and rephrased and sent in iterative fashion until consensus was achieved. RESULTS: Two Delphi rounds were conducted and response rates were 74% (23 out of 31 experts) for the first and 81% (27 out of 33 experts) for the second round. Consensus was achieved on 106 essential steps for both the IL and McK approach. Cronbach's alpha in the first round was 0.78 (IL) and 0.78 (McK) and in the second round 0.92 (IL) and 0.88 (McK). CONCLUSIONS: Consensus among European experts was achieved on essential surgical steps for both Ivor Lewis and McKeown minimally invasive esophagectomy.

Published
2022

45. Recurrent Disease After Esophageal Cancer Surgery: A Substudy of The Dutch Nationwide Ivory Study

Author

Kalff, M.C., Henckens, S.P.G., Voeten, D.M., Heineman, D.J., Hulshof, M., Laarhoven, H.W.M. van, Eshuis, W.J., Baas, P.C., Bahadoer, R.R., Belt, E.J., Brattinga, B., Claassen, L., Ćosović, A., Crull, D., Daams, F., Dalsen, A.D. van, Dekker, J.W.T., Det, M.J. van, Drost, M., Duijvendijk, P. van, Esser, S. van, Gaspersz, M.P., Görgec, B., Groenendijk, R.P.R., Hartgrink, H.H., Harst, E, Haveman, J.W., Heisterkamp, J., Hillegersberg, R. van, Kelder, W., Kingma, B.F., Koemans, W.J., Kouwenhoven, E.A., Lagarde, S.M., Lecot, F., Linden, P.P. van der, Luyer, M.D., Nieuwenhuijzen, G.A., Olthof, P.B., Peet, D.L. van der, Pierie, J.E.N., Pierik, E., Plat, V.D., Polat, Fatih, Rosman, C., Ruurda, J.P., Sandick, J.W. van, Scheer, R., Slootmans, C.A.M., Sosef, M.N., Sosef, O.V., Steur, W.O. de, Stockmann, H., Stoop, F.J., Vugts, G., Vijgen, G., Weeda, V.B., Wiezer, M.J., Oijen, M.G. van, Henegouwen, M.I. van Berge, Gisbertz, S.S., Kalff, M.C., Henckens, S.P.G., Voeten, D.M., Heineman, D.J., Hulshof, M., Laarhoven, H.W.M. van, Eshuis, W.J., Baas, P.C., Bahadoer, R.R., Belt, E.J., Brattinga, B., Claassen, L., Ćosović, A., Crull, D., Daams, F., Dalsen, A.D. van, Dekker, J.W.T., Det, M.J. van, Drost, M., Duijvendijk, P. van, Esser, S. van, Gaspersz, M.P., Görgec, B., Groenendijk, R.P.R., Hartgrink, H.H., Harst, E, Haveman, J.W., Heisterkamp, J., Hillegersberg, R. van, Kelder, W., Kingma, B.F., Koemans, W.J., Kouwenhoven, E.A., Lagarde, S.M., Lecot, F., Linden, P.P. van der, Luyer, M.D., Nieuwenhuijzen, G.A., Olthof, P.B., Peet, D.L. van der, Pierie, J.E.N., Pierik, E., Plat, V.D., Polat, Fatih, Rosman, C., Ruurda, J.P., Sandick, J.W. van, Scheer, R., Slootmans, C.A.M., Sosef, M.N., Sosef, O.V., Steur, W.O. de, Stockmann, H., Stoop, F.J., Vugts, G., Vijgen, G., Weeda, V.B., Wiezer, M.J., Oijen, M.G. van, Henegouwen, M.I. van Berge, and Gisbertz, S.S.

Abstract

Item does not contain fulltext, OBJECTIVE: This study investigated the patterns, predictors, and survival of recurrent disease following esophageal cancer surgery. BACKGROUND: Survival of recurrent esophageal cancer is usually poor, with limited prospects of remission. METHODS: This nationwide cohort study included patients with distal esophageal and gastroesophageal junction adenocarcinoma and squamous cell carcinoma after curatively intended esophagectomy in 2007 to 2016 (follow-up until January 2020). Patients with distant metastases detected during surgery were excluded. Univariable and multivariable logistic regression were used to identify predictors of recurrent disease. Multivariable Cox regression was used to determine the association of recurrence site and treatment intent with postrecurrence survival. RESULTS: Among 4626 patients, 45.1% developed recurrent disease a median of 11 months postoperative, of whom most had solely distant metastases (59.8%). Disease recurrences were most frequently hepatic (26.2%) or pulmonary (25.1%). Factors significantly associated with disease recurrence included young age (≤65 y), male sex, adenocarcinoma, open surgery, transthoracic esophagectomy, nonradical resection, higher T-stage, and tumor positive lymph nodes. Overall, median postrecurrence survival was 4 months [95% confidence interval (95% CI): 3.6-4.4]. After curatively intended recurrence treatment, median survival was 20 months (95% CI: 16.4-23.7). Survival was more favorable after locoregional compared with distant recurrence (hazard ratio: 0.74, 95% CI: 0.65-0.84). CONCLUSIONS: This study provides important prognostic information assisting in the surveillance and counseling of patients after curatively intended esophageal cancer surgery. Nearly half the patients developed recurrent disease, with limited prospects of survival. The risk of recurrence was higher in patients with a higher tumor stage, nonradical resection and positive lymph node harvest.

Published
2022

46. Severity of oEsophageal Anastomotic Leak in patients after oesophagectomy:the SEAL score

Author

Ubels, Sander, Verstegen, Moniek, Klarenbeek, Bastiaan, Bouwense, Stefan, van Berge Henegouwen, Mark, Daams, Freek, van Det, Marc J, Griffiths, Ewen A, Haveman, Jan W, Heisterkamp, Joos, Koshy, Renol, Nieuwenhuijzen, Grard, Polat, Fatih, Siersema, Peter D, Singh, Pritam, Wijnhoven, Bas P.L., Hannink, Gerjon, van Workum, Frans, Rosman, Camiel, Ubels, Sander, Verstegen, Moniek, Klarenbeek, Bastiaan, Bouwense, Stefan, van Berge Henegouwen, Mark, Daams, Freek, van Det, Marc J, Griffiths, Ewen A, Haveman, Jan W, Heisterkamp, Joos, Koshy, Renol, Nieuwenhuijzen, Grard, Polat, Fatih, Siersema, Peter D, Singh, Pritam, Wijnhoven, Bas P.L., Hannink, Gerjon, van Workum, Frans, and Rosman, Camiel

Abstract

BACKGROUND: Anastomotic leak (AL) is a common but severe complication after oesophagectomy. It is unknown how to determine the severity of AL objectively at diagnosis. Determining leak severity may guide treatment decisions and improve future research. This study aimed to identify leak-related prognostic factors for mortality, and to develop a Severity of oEsophageal Anastomotic Leak (SEAL) score.METHODS: This international, retrospective cohort study in 71 centres worldwide included patients with AL after oesophagectomy between 2011 and 2019. The primary endpoint was 90-day mortality. Leak-related prognostic factors were identified after adjusting for confounders and were included in multivariable logistic regression to develop the SEAL score. Four classes of leak severity (mild, moderate, severe, and critical) were defined based on the risk of 90-day mortality, and the score was validated internally.RESULTS: Some 1509 patients with AL were included and the 90-day mortality rate was 11.7 per cent. Twelve leak-related prognostic factors were included in the SEAL score. The score showed good calibration and discrimination (c-index 0.77, 95 per cent c.i. 0.73 to 0.81). Higher classes of leak severity graded by the SEAL score were associated with a significant increase in duration of ICU stay, healing time, Comprehensive Complication Index score, and Esophagectomy Complications Consensus Group classification.CONCLUSION: The SEAL score grades leak severity into four classes by combining 12 leak-related predictors and can be used to the assess severity of AL after oesophagectomy.

Published
2022

47. Recurrent Disease after Esophageal Cancer Surgery: A Substudy of The Dutch Nationwide Ivory Study

Author

MS CGO, Cancer, Heelkunde Opleiding, Externen Med. Onco, Kalff, Marianne C, Henckens, Sofie P G, Voeten, Daan M, Heineman, David J, Hulshof, Maarten C C M, van Laarhoven, Hanneke W M, Eshuis, Wietse J, Baas, Peter C, Bahadoer, Renu R, Belt, Eric J T, Brattinga, Baukje, Claassen, Linda, Ćosović, Admira, Crull, David, Daams, Freek, van Dalsen, Annette D, Dekker, Jan Willem T, van Det, Marc J, Drost, Manon, Duijvendijk, Peter van, Esser, Stijn van, Gaspersz, Marcia P, Görgec, Burak, Groenendijk, Richard P R, Hartgrink, Henk H, Harst, Erwin van der, Haveman, Jan Willem, Heisterkamp, Joos, Hillegersberg, Richard van, Kelder, Wendy, Kingma, B Feike, Koemans, Willem J, Kouwenhoven, Ewout A, Lagarde, Sjoerd M, Lecot, Frederik, van der Linden, Philip P, Luyer, Misha D P, Nieuwenhuijzen, Grard A P, Olthof, Pim B, van der Peet, Donald L, Pierie, Jean-Pierre En, Pierik, E G J M Robert, Plat, Victor D, Polat, Fatih, Rosman, Camiel, Ruurda, Jelle P, van Sandick, Johanna W, Scheer, Rene, Slootmans, Cettela AM, Sosef, Meindert N, Sosef, Odin V, de Steur, Wobbe O, Stockmann, Hein B A C, Stoop, Fanny J, Vugts, Guusje, Vijgen, Guy H E J, Weeda, Víola B, Wiezer, Marinus J, van Oijen, Martijn G H, van Berge Henegouwen, Mark I, Gisbertz, Suzanne S, MS CGO, Cancer, Heelkunde Opleiding, Externen Med. Onco, Kalff, Marianne C, Henckens, Sofie P G, Voeten, Daan M, Heineman, David J, Hulshof, Maarten C C M, van Laarhoven, Hanneke W M, Eshuis, Wietse J, Baas, Peter C, Bahadoer, Renu R, Belt, Eric J T, Brattinga, Baukje, Claassen, Linda, Ćosović, Admira, Crull, David, Daams, Freek, van Dalsen, Annette D, Dekker, Jan Willem T, van Det, Marc J, Drost, Manon, Duijvendijk, Peter van, Esser, Stijn van, Gaspersz, Marcia P, Görgec, Burak, Groenendijk, Richard P R, Hartgrink, Henk H, Harst, Erwin van der, Haveman, Jan Willem, Heisterkamp, Joos, Hillegersberg, Richard van, Kelder, Wendy, Kingma, B Feike, Koemans, Willem J, Kouwenhoven, Ewout A, Lagarde, Sjoerd M, Lecot, Frederik, van der Linden, Philip P, Luyer, Misha D P, Nieuwenhuijzen, Grard A P, Olthof, Pim B, van der Peet, Donald L, Pierie, Jean-Pierre En, Pierik, E G J M Robert, Plat, Victor D, Polat, Fatih, Rosman, Camiel, Ruurda, Jelle P, van Sandick, Johanna W, Scheer, Rene, Slootmans, Cettela AM, Sosef, Meindert N, Sosef, Odin V, de Steur, Wobbe O, Stockmann, Hein B A C, Stoop, Fanny J, Vugts, Guusje, Vijgen, Guy H E J, Weeda, Víola B, Wiezer, Marinus J, van Oijen, Martijn G H, van Berge Henegouwen, Mark I, and Gisbertz, Suzanne S

Published
2022

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