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Glucosinolates are important bioactive molecules and widely found in Brassicaceae species (cress, brussels sprouts, mustard, broccoli, kale etc.). Depending on the amount of these vegetables consumed, both positive and negative metabolic effects from glucosinolate metabolites may occur. The aims of this study were to; investigate inexpensive animal food sources that both increases weight gain and provides enhanced performance parameters without adversely affecting the animal’s health and metabolism; to evaluate dose adjustment of food containing glucosinolates in animals; and to evaluate changes in the biochemical and performance status of chickens on these glucosinolate containing diets. A total of 624 one-day-old Ross 308 broiler line chicks were divided into one control and three treatment groups. Cress seed (Lepidium sativum) was added 0.05% for the first treatment groups (Group 1, 10 g/kg), 0.10% for the second treatment groups (Group 2, 20 g/kg) and 0.15% for the last treatment groups (Group 3, 30 g/kg) to the diet. Serum samples were evaluated for serum glucose, adiponectin, leptin, growth hormone, estradiol and cortisol levels. Performance parameters investigated included feed intake, live body weight and feed conversion ratio. . The villus length, number of goblet cells, crypt depth were determined for histological analyses. According to histological results, villus length was significant at p < 0.05 level between control and group 1 and at p < 0.001 level with groups 2 and 3 at 21 days. The depth of the crypts belonging to the control and experimental groups was not significant between the control group and the group 1 when the statistic was evaluated on the 21st day, whereas between the control group and the group 2, p < 0.05 and p < 0.01; statistical significance was found at p < 0.001 level between group 3 and control group. The results showed that dietary glucosinolate supplementation as feed additive (10, 20 and 30 g/kg) did not significantly improve the dietary performance, or carcass parameters of broiler chickens. Feed intake was the highest in group 2 (20 g/kg), female live weight was the highest in group 2 (20 g/kg) and 3 (30 g/kg). In conclusion, the rates of the cress seed (0.05, 0.10 and 0.15%) that contain glucotropaeolin were not affected for feed additive on performance (especially live weight and live weight gain) and carcass parameters.

Glucosinolates in the nutrition are very important molecules and widely found in Brassicaceae species (brussels sprouts, Dijon mustard, broccoli, cress etc.). Depending on the amount of these kinds of vegetables consumed by humans and animals, some positive or negative metabolic effects of this molecule may occur. Chemically GLS’s are the anticarsinogenic molecules that increase the antioxidan effect, the antibiotic activity and induced the phase-II detoxification enzymes. However, there are the studies shown that I3C, a member of the hydrolysis products of GLS’s, stimulated and inhibited the carsinogenesis. While the low doses of GLS's may be the antiostrogenic effect, the high doses can an estrogen agonist. Due to the lack of scientific data regarding the dose of the molecule that induces favorable and unfavorable effects on the target tissue, our knowledge of this molecule on induction of potential carcinogenic/anticarcinogenic, estrogenic/antiestrogenic, antibiotic effects as well as on regulation of energy balance remains largely insufficient. They constitute the liver, thyroid, rectum abnormalities, and deterioration in the development and reproductive performance. Especially the biological effects, that defines the need to study GLS bioavailability, critically assess the current state of the art on GLS bioavailability, indicate human and animal data on important individual compounds and structural groups, and give recommendations for future research.