Search

Previous investigations have revealed that a functional fermented orange beverage presented in its composition different phenolic compounds, which through in silico investigation demonstrated to have biological effects of therapeutic importance as antioxidant, gastrorepair, and anti-ulcerative properties. Thus, this study confirmed in vivo, through a model of EtOH-induced gastric ulcers in rats, the beneficial properties indicated by the in silico tests. Gastric ulcer was induced by EtOH (intragastric) and was treated after 1 h with fermented orange beverage with and without Mentha piperita extract (0.5 mL/100 g w.b). Omeprazole was used as positive control. Histopathological evaluation revealed that EtOH administration resulted in the formation of gastric ulcers due to the reduction of the mucus layer, presence of hemorrhage, and infiltration of neutrophils in the stomach tissue of rats, and only treatment with omeprazole was able to reverse these changes. Additionally, EtOH administration altered the gastric juice volume and induced oxidative stress in the gastric tissue observed through the increase in lipid peroxidation (TBARS), reduction in the levels of non-protein thiols (NPSH), and alteration in the superoxide dismutase (SOD) activity. The ingestion of the fermented orange beverage increased NPSH levels and reduced changes in TBARS levels induced by ethanol. These findings suggested that the fermented orange beverage has antioxidant effects, as pointed out by in silico studies, but not gastrorepair and anti-ulcerative effects. [ABSTRACT FROM AUTHOR]

Objective: To develop a rapid method for analysing polyphenols, which are potentially active antioxidants against neonatal oxidative stress, from small human milk (HM) volumes. Methods: Acid and alkaline extractions were compared using two dyes: Folin-Ciocalteu and Fast Blue BB. Linearity, sensitivity, recovery percentage, polyphenol content, precision, and stability were assessed in 14 HM samples and compared using the KruskalWallis H test (p<0.05). The best technique was applied to 284 HM samples to determine their polyphenolic content and its association with maternal diet by multifactorial linear regression. Results: Acidic extraction successfully recovered the gallic acid reference standard, whereas alkaline extraction overestimated it. Calibration curves for all methods were linear (R²>0.96) up to 500 mg/L. All bicarbonate-based Folin-Ciocalteu methods assayed were stable and repeatable, whereas Fast Blue BB-based variants were not. HM polyphenols (mean=94.68 mg/L) positively correlated to the dietary intake of hydroxycinnamic acids, the most consumed polyphenolic family in this population. Conclusions: A bicarbonate-based Folin-Ciocalteu micromethod allowed the accurate determination of polyphenols in HM, which might be useful for translational research settings and HM banks. [ABSTRACT FROM AUTHOR]

Copyright of Revista Brasileira de Engenharia Agricola e Ambiental - Agriambi is the property of Revista Brasileira de Engenharia Agricola e Ambiental and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objetivou-se com este estudo avaliar a influência dos processos de extração arraste de vapor (S1) e enzimático (S2) sobre a composição polifenólica de sucos de uva das variedades Bordô, Concord e BRS Violeta produzidos na região do Vale do Rio do Peixe-SC. Foram identificados e quantificados 12 compostos fenólicos por cromatografia líquida de alta eficiência com detector de arranjo de diodos (CLAE-DAD), que diferiram sua concentração de acordo com a variedade e sistema de extração. A partir de análises de componentes principais observou-se que ‘BRS Violeta’ apresentou forte correlação com os ácidos cafeico e 4-hidroxibenzóico, bem como, com catequina e tirosol e a soma dos compostos fenólicos. ‘Bordô’ no S1 e S2 apresentaram a maior concentração para t-resveratrol e ácido vanílico. ‘Concord’ S1 e S2, apresentaram as menores concentrações de fenóis. A variedade foi determinante para a concentração final de cada composto fenólico, devido aos determinantes genéticos e propriedades tecnológicas. Os sistemas de extração influenciam na composição fenólica dos sucos, no entanto, o impacto sobre cada composto específico foi diferente em cada variedade.

Copyright of Arquivos de Ciências da Saúde da UNIPAR is the property of Associacao Paranaense de Ensino e Cultura and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista de Ciências Agrárias is the property of Sociedade de Ciencias Agrarias de Portugal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Nativa is the property of Revista Nativa and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Brazilian Journal of Biology is the property of Instituto Internacional de Ecologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Introdução: O estresse oxidativo está envolvido na fisiopatologia da hipertensão arterial sistêmica (HAS) e o papel dos antioxidantes nesse contexto ainda precisa ser melhor compreendido. Objetivo: avaliar a prevalência de hipertensão e a relação com ingestão de polifenóis e capacidade antioxidante total dietética (DTAC) em mulheres climatéricas da Serra Gaúcha-RS, Brasil. Materiais e métodos: 41 mulheres participaram do estudo (CEP 2.420.632; 07/12/2017) e foram submetidas a aferições de peso, altura, circunferência da cintura e pressão arterial. Aplicaram-se diferentes questionários visando a obtenção de informações sociodemográficas e de saúde, além do Recordatório Alimentar de 24 horas. Comparações entre os grupos hipertenso e não hipertenso foram feitas através de teste t de Student ou qui-quadrado. Resultados: A prevalência de HAS na população foi de 29,27 % (IC95% 14,73; 43,81) e as mulheres hipertensas apresentaram IMC estatisticamente superior ao das não hipertensas (p=0,047). Embora sem diferença estatística, observou-se que o grupo hipertenso apresentou DTAC e ingestão de polifenóis totais diminuídos (9 e 11 % de redução, respectivamente). O mineral magnésio teve sua ingestão significativamente reduzida (30 %; p=0,006) pelas mulheres hipertensas. Observou-se que elas exibiram uma ingestão abaixo do recomendado para as vitaminas A e E. Dentre os alimentos e bebidas que contribuíram para aumentar a DTAC das participantes, o café ficou em primeiro lugar em ambos os grupos. Conclusão: Esses dados demonstram a importância do monitoramento do consumo de antioxidantes visando a prevenção e/ou controle da hipertensão e de doenças relacionadas à saúde do coração, em mulheres climatéricas.

Resumo O objetivo deste trabalho foi avaliar o efeito do retardo de resfriamento de morangos ‘San Andreas’ sobre a manutenção da qualidade dos frutos, bem como sobre os compostos fenólicos totais (CFT) e a atividade antioxidante total (AAT), após o armazenamento refrigerado. Os tratamentos consistiram no resfriamento nos tempos de 0 (controle, resfriamento imediato), 3, 6, 9 e 12 horas (em temperatura ambiente), após a colheita. Após a aplicação dos tratamentos, os frutos foram armazenados sob refrigeração (4 ± 0,5 °C e 92 ± 2% de UR), durante 5, 6, 7 e 8 dias, seguidos por mais 2 dias de exposição, em condição ambiente (20 ± 2 °C e 65 ± 5% de UR). Os morangos com o maior retardo de resfriamento apresentaram maior perda de massa fresca, além de menor firmeza, a partir de 7 dias de armazenamento. De maneira geral, os menores valores de incidência e severidade de podridões foram observados nos frutos do tratamento com resfriamento imediato após a colheita, quando armazenados por 7 e 8 dias, seguidos por mais 2 dias em condições ambiente. O retardo do resfriamento por até 6 horas não causa aumento de podridões até 5 dias de armazenamento refrigerado, mais 2 dias em condições ambiente. Os valores de CFT e AAT apresentaram aumento com o retardo de até 6 horas do resfriamento dos frutos, aos 6 dias de armazenamento seguidos por mais 2 dias em condições ambiente, e a AAT aumentou com o aumento do atraso no resfriamento dos frutos em até 12 horas, após 8 dias de armazenamento mais 2 dias em condições ambiente. O atraso no resfriamento causa perdas na qualidade dos frutos de morango, de acordo com o tempo de armazenamento.

Low to moderate concentrations of condensed tannins in ruminant diets are considered to increase the postruminal flow of non-ammonia nitrogen. The objective of this research was study the microbial protein synthesis and nitrogen balance of lactating cows fed with a diet of two tannin sources, based on sorghum (condensed tannin) with increasing levels of tannic acid (hydrolysable tannin). So, increasing levels of tannic acid in a sorghum-based diet for five Holstein/Zebu crossbred lactating heifers were subject to a 5 × 5 Latin square experimental design, five heifers x five tannins acid levels x five periods. The excretion of total purine derivatives, through the collection of spot urine samples, and the N concentration values in the milk and urine were used. All heifers received 9.87 kg/DM of corn silage as roughage and 6.38 kg of concentrate (not fed ad libitum). Diet 1 (control) contained low-tannin sorghum (0.027 kg total tannin), and the other diets contained high-tannin sorghum. The levels of tannic acid added used were established based on the quantity of condensed tannin in high-tannin sorghum. Thus, diets 2, 3, 4, and 5 were supplemented with 1.5g (13% DM), 79.5g (2.6% DM), 157.5 g (3.9% DM), and 235.5 g (5.2% DM) of tannic acid totalling 0.078, 0.156, 0.234, and 0.321 total tannin kg/day respectively. The urinary excretions of urea (2.0055), total allantoin (185.12 mmol/day-1), and total purine derivatives (222.32 mmol/day-1); absorbed purines 179.3 mmol/day-1); the N microbian synthesis (130.358 (g)N/day-1); and the concentrations of allantoin in milk (36.40 mmol/day-1) were not affected by the diets. Diets using two tannins (hydrolysable and condensed) sources supplementation didn't affect the animals' health, neither improved the microbial synthesis efficiency nor the N balance for milk production. [ABSTRACT FROM AUTHOR]

Croton floribundus, Euphorbiaceae, popularly known as "capixingui" is a native tree of the Atlantic Forest. In folk medicine, the tea of C. floribundus stem bark is used for the treatment of leukemia, tumors, and syphilis. The aim of this work was to describe the morphological and anatomical characteristics of C. floribundus stem bark and to establish parameters for its quality control. Accordingly, different analyses were performed, including organoleptic, morphological, anatomical, and histochemical analysis of the samples, plus the characterization of druse crystals by energy-dispersive X-ray spectroscopy. The sample showed menthol and camphor odor, and bitter taste. The main macroscopic characteristic was the presence of a thin periderm with striations. The main distinctive microscopic features of the species were: dense gelatinous fibers, phenolic idioblasts, sclereids, numerous crystalline idioblasts with druses located in the cortex and abundantly in the parenchymal rays of the phloem, and absence of laticifers in the mature stem bark. These analyses made possible to describe the morpho-anatomy of that species, contributing to phytochemical and pharmacognostic future studies of C. floribundus. [ABSTRACT FROM AUTHOR]

Copyright of Brazilian Journal of Biology is the property of Instituto Internacional de Ecologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Brazilian Journal of Biology is the property of Instituto Internacional de Ecologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Viticulture & Enology / Ciência e Técnica Vitivinícola is the property of EDP Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Resumo Objetivou-se realizar a caracterização físico-química e dos compostos bioativos do extrato aquoso de amendoim sem pele e acrescido de 1% de pele. Os extratos aquosos de amendoim sem e com pele foram caracterizados quanto aos parâmetros: umidade, extrato seco total, cinzas, lipídios, proteínas, teor de sólidos solúveis, acidez titulável, pH, carboidrato e fibras totais, além de compostos fenólicos e flavonoides. Os percentuais de umidade encontrados foram elevados em todas as amostras, resultante de sua base de extrato aquoso produzido na proporção 1:8 (amendoim:água). Observou-se que os extratos aquosos de amendoim sem pele e acrescido de 1% de pele não apresentaram diferença significativa entre si para os parâmetros de pH, como também para sólidos solúveis totais, lipídios e carboidratos. No entanto, a acidez, proteínas, fibras e cinzas apresentaram diferença estatística. Na determinação de compostos fenólicos, notou-se que o extrato aquoso de amendoim com pele apresentou uma quantidade maior quando comparado ao sem pele. Quanto aos flavonoides, a maior quantidade também foi encontrada na amostra com pele, apresentando uma diferença média de 2,52 µg/100 g base úmida. Os extratos aquosos de amendoim com e sem pele mostraram ser uma valiosa alternativa para um melhor aproveitamento do amendoim, proporcionando à população um produto nutricional. A bebida acrescida de 1% de pele enriqueceu o produto quanto ao potencial antioxidante devido às suas maiores concentrações de compostos fenólicos totais e flavonoides.

The interest in the study of "Unconventional Edible Plant" has been growing, driven mainly by the growing trend of consumption by the population. This is the case of the Urticaceae family that has species described by possessing nutritional properties, which can be added to products as a functional food. Despite this evidence, studies on the chemical composition and biological properties of this family are still scarce. In this context, the objective of the present study was to evaluate the nutritional composition, antioxidant activity, total phenolic content and major compounds of four species of the Urticaceae family (Boehmeria caudata Sw., Urera baccifera (L.) Gaudich. Ex Wedd., Urtica circularis (Hicken) Sorarú and Urtica dioica (L.) collected in southern Brazil The results showed that the U. baccifera species was the one with the highest moisture content (11.02%) and dietary fiber (43.85 The species U. circularis had the highest content of total minerals (20.95%) and protein (26.6%), while B. caudata had the highest carbohydrate content (7.64%). Regarding the total phenolic content, a higher content was observed for the species B. caudata and U. dioica (274.92 ± 6.05 and 260.84 ± 8.56 mg GAE / g, respectively), with hesperidin being the flavonoid majority, detected in the species U. baccifera (116.49 ± 0.94 µg / mL). Taken together, the results demonstrate that the species of the family Urticacea, typically known for their stinging properties, can be considered good sources of nutrients and bioactive compounds with antioxidant capacity. [ABSTRACT FROM AUTHOR]

Introduction: Oxidative stress is involved in the pathophysiology of systemic arterial hypertension (HAS) and the role of antioxidants in this context still needs to be better understood. Objective: To evaluate the prevalence of hypertension and the relationship with polyphenol intake and total dietary antioxidant capacity (DTAC) in climacteric women from Serra Gaúcha-RS, Brazil. Materials and methods: 41 women participated in the study (CEP 2,420,632; 12/07/2017) and they were subjected to measurements of weight, height, waist circumference, and blood pressure. Different questionnaires were applied to obtain sociodemographic and health information, in addition to the 24-hour Food Recall. Comparisons between the hypertensive and non-hypertensive groups were made using Student's t-test or chi-square. Results: The prevalence of HAS in the population was 29,27 % (IC95% 14,73; 43,81) and hypertensive women had a BMI statistically higher than nonhypertensive women (p=0.047). Although without a statistical difference, it was observed that the hypertensive group had decreased DTAC and total polyphenol intake (9 and 11% reduction, respectively). The mineral magnesium had its intake significantly reduced (30%; p=0.006) by hypertensive women. This group also had an intake below the recommended for vitamins A and E. Among the foods and beverages that contributed to increasing the participants' DTAC, coffee ranked first in both groups. Conclusion: These data demonstrate the importance of monitoring the consumption of antioxidants to prevent and/or control hypertension and diseases related to heart health in climacteric women. [ABSTRACT FROM AUTHOR]

Objectives: To determine the phytochemical composition and evaluate the antioxidant activity of the hydroalcoholic extracts of S. haematospermum; P. niruri; P. tenellus; E. serpens. Methodology: The phytochemical composition was analyzed by thin layer chromatography and the antioxidant activity was observed qualitatively by autographic assay. Total phenols were quantified with the Folin-Ciocalteu method and total flavonoids with the aluminum complexation reaction. To determine the antioxidant activity, the discoloration techniques of the free radical DPPH• (2,2-diphenyl-1-picrilhydracil) and of the cation radical ABTS•+ (2,2-Azino-bis-3-ethylbenzothiazolin-6-sulfonic acid) and the reducing power of the iron (III) cation. Results: The phytochemical study showed the presence of bioactive metabolites in all species. The total phenol content ranged from: 627.71 ± 1.45 to 369.8 ± 52.6 mg EAG / g sample and total flavonoids was 12.2 ± 0.1 to 4.5 ± 0.3 mg Q / g sample. The species S. haematospermum and P. tenellus presented higher content of polyphenols. The antioxidant activity tests allowed recognizing that S. haematospermum and P. tenellus have a capacity for greater inhibition of the tested free radicals and the hydroalcoholic extracts S. haematospermum and P. niruri showed greater reducing power. [ABSTRACT FROM AUTHOR]

Aim: To evaluate the antioxidant and anti-inflammatory activity in hydroalcoholic extracts of the aerial parts of Kalanchoe daigremontiana Raym. -Hamet & H. Perrier. Materials and methods: Extracts were obtained using ethanol (EtOH) and methanol (MeOH) as solvents at different concentrations. Total phenols and flavonoids were quantified using the Folin-Ciocalteu method and the aluminum complexation reaction, respectively. Methodology: The antioxidant activity of the extracts was determined using the DPPH• (2,2-diphenyl-1-picrylhydracil) free radical discoloration technique, while lipoxygenase (LOX) inhibition assays were used to measure the anti-inflammatory activity. Results: The 70% ethanolic extract showed a greater antioxidant capacity against DPPH• and a greater inhibition of the lipoxygenase enzyme, which should be related to the overall phenols and flavonoids content, suggesting that K. daigremontiana exhibits antioxidant and anti-inflammatory properties. [ABSTRACT FROM AUTHOR]

Copyright of Innotec is the property of Laboratorio Tecnologico del Uruguay and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Many native species from the Cactaceae family with occurrence in northeastern Brazil have been investigated targeting their chemical composition and functional properties as strategy of adding value to these species that are underexploited according to ethnobotanical studies. The xiquexique (Pilosocereus gounellei (A. Weber ex K. Schum.)) is one of these species that adapts in high temperatures and low rainfall environments and some local populations use it for several purposes, including animal feeding and medicinal. However, there is few studies regarding the physical and physicochemical characterization and on the compounds of functional interest in fruits of this species. In the context, the aim of this study was to evaluate the physical and physicochemical characteristics, bioactive compounds and antioxidant activity of the xiquexique fruit from plants occurring in three municipalities of the state of Paraíba, Brazil. The pulp of fruits from the municipalities of Boqueirão and Solânea presented lower acidity content, with higher SS/AT ratio and may be more suitable for fresh consumption. Furthermore, fruits from these municipalities can be also attractive for processing once they had larger sizes. Fruits of xiquexique exhibited high contents of functional compounds such as phenolic and betalains, which provided high antioxidant activity, with potential for adding value.

Copyright of Brazilian Journal of Biology is the property of Instituto Internacional de Ecologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Yerba mate leaves are traditionally consumed and known by their high concentration of polyphenols. The spectrophotometric method commonly used to analyze Total Polyphenols Content (CFT) is Folin-Ciocalteu, in which a standard curve of gallic acid is used and the absorbance of samples is analyzed using 765 nm wave-length. The aim of this work was to adapt Folin-Ciocalteu method in order to determinate CFT of yerba mate extract reducing reagents use and reaction time, providing efficiency and economy. Therefore, the kinetics of the reaction was studied and a modification of the inclination of the kinetic curve in 30 minutes reaction time was observed. In order to evaluate the adequacy of the reaction time to 30 minutes, standard curves were obtained by three different analysts and the results were compared to 2 hour reaction time analyses, according to Folin-Ciocalteu method. The results were expressed in gallic acid equivalent (EAG). The absorbance results ranged from 0.004 ± 0.004 (0 mg EAG L-1) to 1.187 ± 0.100 (1000 mg EAG L-1) for the reaction of 2 hours. In the reaction of 30 minute these values ranged from 0.005 ± 0.004 (0 mg EAG L-1) to 1.177 ± 0.022 (1000 mg EAG L-1). These methods were used to quantify the CFT in yerba mate leaves and the results were 58.33 ± 3.90 mg EAG g-1 (traditional method) and 57.77 ± 2.70 mg EAG g-1 (adapted method). These results demonstrate the adapted method reproducibility, showing its usefulness to obtain greater efficiency and economy in the analysis. [ABSTRACT FROM AUTHOR]

Copyright of Arquivos de Neuro-Psiquiatria is the property of Thieme Medical Publishing Inc. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Grumixama (Eugenia brasiliensis Lam.) is a Brazilian berry native to the Atlantic Rainforest. Information on nutritional and bioactive profiles of the fruit cultivated in the Brazilian Savannah (Cerrado) is not available in literature. The aim of this study was to investigate the physical and proximate composition; mineral, total phenolics, total tannins and total carotenoids contents; and antioxidant capacity (DPPH and FRAP assays) of the dark purple grumixama cultivated in the Cerrado area (Goiás State). Results showed a similar physical and proximate composition to those of grumixama native to the Atlantic Rainforest. However, grumixama from Cerrado presented the highest dietary fiber and magnesium contents. In addition, the Cerrado grumixama showed higher content of total phenolics (with a large amount of tannins), carotenoids and antioxidant capacity than those of grumixama native to the Atlantic Rainforest, cherry, blueberry, and fruits native to the Cerrado. Thus, the consumption of whole fruit (peel, pulp and seed) in healthy diets and its use as an ingredient for functional food products should be encouraged. [ABSTRACT FROM AUTHOR]

Introduction: the extraction of polyphenols has taken an interest due to the relationship it has with the prevention of oxidative stress and beneficial effects on health in the prevention of non-communicable diseases. These are commonly found in some fruits, so their extraction has become a trend to obtain products with high added value. Ultrasound is a technique that can decrease the extraction time of these biocomponents. Objective: the main objective of this work was to evaluate the conditions of the ultrasound-assisted extraction of polyphenols with antioxidant activity in dehydrated peel yellow pitahaya. Materials and methods: the kinectis drying was made at 60 °C, in order to decrease deterioration reactions. For the extraction, a solution of 96% ethanol (V / V) was used as disolvent; the ratio Peel-Disolvent was 1:1. The process was performed at 25 °C and 37 kHz frequency. A central composite design was used, in which the effect of power (40 - 80%) and ultrasonication time (11.90 - 33.10 minutes) were evaluated. One control point was evaluated with Soxhlet extraction. The extracted amount of polyphenols and antioxidant capacity was determined by Folin- Ciocalteau and ABTS methods, respectively. Results: lower time exposures and higher sonication power were associated with increases in polyphenols and antioxidant capacity. In particular, ultrasound-assisted extraction in 60% power and 11 min, obtained 77% more polyphenols than 24-h standard method (Soxhlet). Conclusion: Ultrasound has potential compared to the traditional technique to reduce the processing time in biocomponent extraction, in this case taking advantage of the yellow pitahaya peel that is considered as a residue, polyphenol concentrations of 973.10 mg / L were found that They can be extracted by ultrasound at 222 W nominal power (60%), 35kHz frequency and 22 minutes and with an antioxidant capacity of over 90%. [ABSTRACT FROM AUTHOR]

Copyright of Brazilian Journal of Applied Technology for Agricultural Science / Revista Brasileira de Tecnologia Aplicada nas Ciências Agrárias is the property of Brazilian Journal of Applied Technology for Agricultural Science and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

This study aimed to evaluate the in vitro anthelmintic activity of Mimosa caesalpinifolia (sabiá) ketone extract, which is rich in condensed tannins (CT), on Haemonchus contortus and Trichostrongylus colubriformis. The leaves and stems of M. caesalpinifolia were collected, dried in the shade, and ground to a dry powder from which ketone extracts were obtained for in vitro assays. The extracts were diluted in 5% acetone and PBS to concentrations in the range 0.25-2.80 mg mL-¹ and the inhibition of egg hatchability was assayed. Feces collected from goats naturally infected with H. contortus (55%) and T. colubriformis (45%) were macerated and the helminth eggs were collected to conduct in vitro egg hatchability tests. Nematode larvae collected from the feces were used for a larval exsheathment inhibition assay of M. caesalpinifolia leaf and M. caesalpinifolia leaf and stem ketone extracts at concentrations of 0.6 and 1.2 mg mL-¹; three replicates were performed for each concentration. PBS was used as a negative control. Polyvinylpolypyrrolidone (PVPP) was added to the extracts to assess the effect of phenolic compounds on anthelmintic activity. An inhibitory effect of 80.7% and 82.3% was observed on hatchability after treatment with 1.0 and 2.0 mg mL-¹ M. caesalpinifolia leaf ketone extract, respectively. An inhibition rate lower than 75% was observed for 1.0 mg mL-¹ M. caesalpinifolia leaf and stem ketone extract. The M. caesalpinifolia leaf ketone extract larval exsheathment assay resulted in inhibition of 97.3% and 99.8% at concentrations of 0.6 and 1.2 mg mL-¹, respectively. For the leaf and stem ketone extract, the larval exsheathment inhibition was 94.3% at 1.2 mg mL-¹. The leaf and leaf and stem extracts showed no inhibitory effects on larval exsheathment after the addition of PVPP. These results showed that cuticular loss was related to the action of the phenolic compounds in the M. caesalpinifolia extracts. M. caesalpinifolia leaf ketone extract inhibited egg hatchability, but the leaf and stem extract showed lower efficiency, which indicated a greater abundance of active compounds in the leaves. The M. caesalpinifolia ketone extracts were effective in the inhibition of larval exsheathment at the highest concentration tested. Based on these results, in vivo studies should be performed to demonstrate the anthelmintic activity of this plant in goats.

In the present study, nonfat yoghurt made with whey protein isolate (WPI) or pasteurized egg white powder (albumin) was added with syrup containing jaboticaba pulp and lyophilized jaboticaba peel flour and six experimental groups were made: control yoghurt (CY); WPI yoghurt (WY); albumin yoghurt (AY), syrup yoghurt and WPI (WSY); syrup and albumin yoghurt (ASY) and syrup yoghurt (SY). This study aimed to verify the influence of the addition of fruit syrup on the phenolics compounds and on the instrumental color parameters of yoghurts made with proteins on the 1st and 28th day of storage. There was a significant decrease in total phenolics content in yoghurt containing WPI and syrup (from 1408.14mg GAE.L-1 to 686.73mg GAE.L-1), as well as total anthocyanin content. However, yoghurt containing syrup and albumin showed an increase in total flavonoid content on day 28 of storage (from 28.30mg QE.100g-1 to 38.29mg QE.100g-1). Regarding color, there was an increase in L* and b* values in yoghurt containing syrup and WPI and in yoghurt containing syrup and albumin. For a* values, a decrease was observed at the end of the storage period in samples containing protein (WPI or albumin) and syrup. The data showed that the addition of jaboticaba syrup to yoghurts containing different proteins provided different phenolics compounds contents at the end of the storage period, and different color parameters to the final product. [ABSTRACT FROM AUTHOR]

The aim of this study was to examine the impact of cultivar and spear color on the composition of polyphenols in asparagus spears (Asparagus officinalis). The five genotypes (Schwetzinger Meisterschuss, Huchel's Alpha, Gijnlim, Grolim and Eposs) and three growing conditions of asparagus spears (Asparagus officinalis) were investigated. The polyphenols were determined by applying the HPLC-DAD system. The obtained results were subjected to the principal component analysis. Among the analyzed asparagus samples cv. Grolim contained the highest amounts of phenolic acids and flavonols. The varied quantitative and qualitative composition of polyphenolics resulted most probably from changes occurring during vegetation, such as a lack of access to light in the case of white asparagus and limited access to light in purple asparagus. The scavenging activity on DPPH radicals by asparagus extract is dependent on the variety and color and was the greatest for green asparagus samples. Similar green extracts scavenged ABTS radicals to the highest degree. Results of this study suggested that asparagus may constitute a good source of natural antioxidants to be used in our diet as well as by industries for functional food formulations. [ABSTRACT FROM AUTHOR]

Nutraceuticals are foods or part of a food that provide health benefits, including the prevention and / or treatment of diseases. In this sense, curcumin, the main active compound of turmeric, popularly known as saffron, deserves considerable attention as a nutraceutical because, despite high chemical instability, it can prevent and treat complex multigenic diseases, mainly due to its antioxidant action. Therefore, nanotechnology comprises an important tool to improve compounds with proven therapeutic activity, but with a reduced pharmacokinetic profile, such as curcumin. This literature review describes the results of studies using nanostructured systems containing curcumin as nutraceuticals. The systematic review of the literature was carried out by searching for original articles that addressed the topic of interest published in the last 10 years. The results showed variety regarding the type of polymer and the method of obtainment used in the preparation of nanostructured systems described in the literature. However, in general, nanoencapsulated curcumin showed similarities in its physico-chemical characteristics and better biological performance when compared to free curcumin, overcoming the limitations of its use. Therefore, curcumin is a good example of a naturally occurring substance which therapeutic properties can be enhanced through the use of nanotechnology. [ABSTRACT FROM AUTHOR]

Since mate is a source of several bioactive compounds, it has been the object of many studies. Extract preparation from its leaves is the extraction of health-giving compounds, such as polyphenols and antioxidants. Several methodologies for the preparation of liquid and hydro-alcoholic extracts from leaves are described where time, temperature, particle size, solute-solvent ratio and shake intensity affect the quality of the extract obtained. Current research compares and establishes temperature and time conditions for the highest rates in total phenolic compounds and antioxidant activity (%AA) in mate extracts. Seven methods described in the literature were selected, with five for aqueous extracts and two for hydro-alcoholic extracts. TPCs were determined by Folin-Ciocalteu, with modifications, for microplate protocols, and %AA by the DPPH (1,1-difenil- 2-picril-hidrazil) method. TPC's quantitive analysis ranged between 2,113 and 2,423 mg EAG L-1 for aqueous extracts and between 2,707 and 2,997 mg EAG L-1 for hydro-alcoholic extracts. Antioxidant activity ranged between 39.8% and 55.27%. Extracts with the highest TPC and %AA rates were aqueous extract obtained at 85°C for 10 min heating and hydro-alcoholic extract obtained at room temperature (25-20°C) with 120 min of extraction. Extracts may be added to food, with antioxidant capacity and functional properties. [ABSTRACT FROM AUTHOR]

A pesquisa foi direcionada para abordar as características peculiares do vinho, visando esclarecer os seus benefícios, considerando alguns ativos presentes sua composição. O objetivo foi elucidar o quê, como e o porquê as substâncias contidas no vinho (em especial, o resveratrol) beneficiam o organismo humano, por meio de um estudo descritivo e retrospectivo utilizando-se como fontes de informação técnico-científica: bases eletrônicas de dados da Scientific Electronic Library Online (SciELO), National Institutes of Health (PubMed e MedLine), Biblioteca Regional de Medicina (BIREME), além de fontes secundárias, no período de 1994 a 2015, que teve como foco de busca os estudos com evidência científica realizados com modelos animais e, também, em humanos, principalmente, quanto aos efeitos do resveratrol. A pesquisa evidenciou a capacidade do resveratrol em evitar a arteriosclerose, as doenças inflamatórias e alérgicas, os problemas cardíacos, entre outros agravos à saúde. Dentre as substâncias encontradas no vinho, o resveratrol destaca-se por suas propriedades terapêuticas benéficas.

Resumo Os resíduos gerados na indústria de sucos têm sido subaproveitados, desperdiçando um produto que pode apresentar potencial para ser incluído na alimentação humana. Assim, o objetivo do estudo foi realizar análise microbiológica e da composição nutricional das farinhas do resíduo de suco de uva, maçã, laranja e acerola, com diferentes granulometrias. Os resíduos da produção de suco foram obtidos através de doação de uma indústria do município de Bento Gonçalves-RS, sendo então secos e moídos para obter a farinha em diferentes granulometrias (>0,600 mm; 0,600 mm; 0,425 mm; 0,300 mm; ≤0,250 mm). As amostras de farinha foram submetidas à análise de composição centesimal, acidez, pH, Brix e polifenóis totais. As análises microbiológicas incluíram contagem de coliformes termotolerantes e pesquisa de Salmonella spp. Os resultados indicaram qualidade microbiológica satisfatória. Quanto à composição centesimal, os resultados mostraram que a granulometria influenciou o valor nutricional das farinhas e que os valores energéticos das farinhas do resíduo de acerola, laranja e uva foram inversamente proporcionais ao tamanho da partícula. Todas as farinhas analisadas podem ser consideradas ricas em fibras, cujos valores variaram de 11,2% a 54,5%. As farinhas de uva e acerola apresentaram maiores teores de proteínas, 8,2% a 15,6% e 8,3% a 12,1%, respectivamente. As farinhas do resíduo de laranja e uva apresentaram elevados teores de polifenóis totais. Portanto, o uso destes resíduos na alimentação humana pode ser recomendado, melhorando o valor nutricional de preparações.

Kinkan orange (Fortunella margarita), commonly known as“golden orange”, is originally from Asia and belongs to the genusFortunella. Kinkan orange has some characteristics of citrusfruits, which are the most consumed fruits by the Brazilianpopulation. Objective: The study aimed to evaluate the chemicalcharacterization of kinkan orange by comparing the resultsobtained with data published on the analysis of some citrus fruitsof great commercial interest in Brazil, such as serra-d’água orange,pera-rio orange, ponkan tangerine and tahiti lime. Methodology:We evaluated pH, soluble solids, titratable acidity, and contentof vitamin C, total phenolics and antioxidant capacity. All testswere performed in triplicate and data were compared by Tukey’stest (p

Resumo: O objetivo deste trabalho foi avaliar a influência dos porta-enxertos 'IAC 766 Campinas' e '106-8 Mgt Ripária do Traviú' sobre as características físico-químicas do mosto e do vinho das uvas 'IAC 116-31 Rainha', 'IAC 21-14 Madalena' e 'BRS Lorena'. O mosto das uvas foi avaliado quanto ao pH, sólidos solúveis (SS), acidez total (AT) e relação SS/AT. No vinho, realizaram-se as seguintes análises físico-químicas: densidade, teor alcoólico; acidez total, volátil e fixa; pH; extrato seco; açúcares redutores; extrato seco reduzido; álcool em peso/extrato seco reduzido; dióxido de enxofre livre e total; índice de polifenóis totais (I 280), polifenóis totais, flavonoides; e atividade antioxidante. As características do mosto da 'IAC 21-14 Madalena' não foram influenciadas pelos porta-enxertos, no entanto, o porta-enxerto 'IAC 766 Campinas' promoveu maior SS/AT no mosto da 'IAC 116-31 Rainha' e menor SS/AT no da 'BRS Lorena. Os porta-enxertos 'IAC 766 Campinas' e '106-8 Mgt Ripária do Traviú' influenciaram o pH e o teor alcoólico do vinho da 'IAC 116-31 Rainha', o extrato seco do vinho da 'IAC 21-14 Madalena' e a acidez fixa do vinho da 'BRS Lorena'. Não houve influência dos porta-enxertos sobre os compostos fenólicos e a atividade antioxidante dos vinhos.

RESUMOA batata-doce (Ipomoea batatas L.) é um vegetal muito cultivado nos países tropicais, usado na alimentação humana e na animal, sendo uma boa fonte de energia, sais minerais e vitaminas. Constitui, ainda, fonte de polifenóis antioxidativos, entre eles, antocianinas e ácidos fenólicos. O objetivo deste estudo foi avaliar a atividade antibacteriana de diferentes extratos de folhas frescas de batata-doce, frente a bactérias de interesse alimentar, e correlacioná-la com os teores de polifenóis totais e de antocianinas. Foram avaliados teores de polifenóis totais e de antocianinas, bem como a atividade antibacteriana de extratos alcoólicos, de infusão e de decocção de folhas de dois acessos de batata-doce, em Porto Alegre, RS, frente a três agentes de interesse em alimentos e alimentação, quais sejam, inóculos padronizados de SalmonellaEnteritidis (ATCC 11076), Staphylococcus aureus(ATCC 25923) e Escherichia coli (ATCC 11229). A avaliação da atividade antibacteriana, expressa em intensidade de atividade de inibição bacteriana (IINIB) e em intensidade de atividade de inativação bacteriana (IINAB), foi baseada em testes de diluição em sistema de tubos múltiplos; as antocianinas foram determinadas por meio de pH diferencial e os polifenóis pelo método de Folin & Ciocalteu. Os extratos alcoólicos inibiram e, ou, inativaram todos os inóculos testados, não obstante o Staphylococcus aureus ter sido significativamente mais resistente. Os extratos obtidos por decocção e infusão, além de apresentarem concentrações muito baixas de antocianinas e menores teores de polifenóis do que os seus correspondentes alcoólicos, não apresentaram atividade antibacteriana. A atividade antibacteriana dos extratos testados foi positivamente correlacionada com os compostos fenólicos e, ou, antocianinas.

RESUMO No Brasil, a família Malvaceae está representada por aproximadamente 200 espécies e algumas foram descritas como gastroproteroras. Pavonia alnifolia A.St.-Hil. (Malvaceae) foi selecionada após uma abordagem quimiossistemática, considerando-se sua potencial capacidade em prevenir lesões gástricas. Assim, a atividade gastroprotetora do extrato etanólico de caules de P. alnifolia foi avaliada utilizando o modelo de indução aguda da lesão gástrica por etanol acidificado em camundongos. Além disso, foram quantificados o teor de flavonóides, pelo método de cloreto de alumínio, e de polifenóis, pelo método Folin-Ciocalteu, uma vez que a relação desses componentes com a proteção gástrica foi evidenciada. Os ensaios apontaram redução acentuada das lesões gástricas em camundongos tratados com o extrato da planta em todas as doses ensaiadas (10, 100 e 300 mg/kg). Esse efeito pode estar relacionado com a presença de polifenóis, cujo teor encontrado foi 74,3 ± 7,5 μg equivalente de pirogalol/mg do material vegetal examinado e 82,7 ± 7,1 μg equivalente de pirogalol /mg da amostra no extrato preparado por percolação e teor de flavonoides totais, que por sua vez apresentou um resultado de 17,1 ± 1,4 μg/mg de extrato. O extrato apresentou proteção da mucosa gástrica e este efeito pode estar relacionado à presença dos polifenóis e flavonóides encontrados.

Resveratrol (RESV) is a polyphenolic compound found in various plants, including grapes, berries and peanuts, and its processed foods as red wine. RESV possesses a variety of bioactivities, including antioxidant, anti-inflammatory, cardioprotective, antidiabetic, anticancer, chemopreventive, neuroprotective, renal lipotoxicity preventative, and renal protective effects. Numerous studies have demonstrated that polyphenols promote cardiovascular health. Furthermore, RESV can ameliorate several types of renal injury in animal models, including diabetic nephropathy, hyperuricemic, drug-induced injury, aldosterone-induced injury, ischemia-reperfusion injury, sepsis-related injury, and endothelial dysfunction. In addition, RESV can prevent the increase in vasoconstrictors, such as angiotensin II (AII) and endothelin-1 (ET-1), as well as intracellular calcium, in mesangial cells. Together, these findings suggest a potential role for RESV as a supplemental therapy for the prevention of renal injury.

The objective of this study was to characterize for the first time polyphenols and DPPH (2-diphenyl-1-picryhydrazyl radical) antioxidant activity in commonly cultivated accessions of Phaseolus lunatus from an ex situ germplasm collection maintained by Embrapa, in Brazil. Furthermore, the study aimed to detect changes in total polyphenols, total flavonoids and condensed tannin for the same accessions after regeneration in a greenhouse. The results showed the diversity of the lima bean collection for phenolic compounds, which were strongly correlated with antioxidant activity. Lima beans accessions with the highest polyphenols and antioxidant activity were those with colored seeds. Conservation through cold storage of P. lunatus seeds in a cold chamber in the germplasm collection did not necessarily affect phenolic compounds. Variations observed in values after regeneration seeds may be mainly results of biotic and abiotic factors, including not only cultivar, but also environmental conditions. This study suggests that polyphenols in the lima beans present antioxidant activity, with possible beneficial effects for human health. It was expected that the potential of this tasty legume can be also used as a functional food crop and/or as a new ingredient in gastronomy.

RESUMO As úlceras pépticas são decorrentes de um desequilíbrio entre os agentes agressores endógenos, exógenos e agentes protetores. Neste estudo avaliou-se a atividade antiulcerogênica in vivo para o extrato aquoso de Salviaofficinalis (EAS). Após os tratamentos (n = 6; v.o) com o controle (C) água; pantoprazol (30 mg/kg) e EAS (100, 250 e 400 mg/kg, respectivamente) os ratos receberam uma solução de HCl 0,3 M em etanol 60% (v.o) e realizaram-se avaliações morfológicas dos estômagos por meio de uma tabela de escores de lesão (ANOVA; one way e Tukey). EAS (400 mg/kg) apresentou atividade antiulcerogênica (31,47%) semelhante ao pantoprazol (33,83%) em comparação (p

Copyright of Brazilian Journal of Biology is the property of Instituto Internacional de Ecologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Shrubs of Syzyngium paniculatum, are found in the city of Bogotá adorning streets, park and gardens, presenting colorful fruits known as magenta cherry, which have no use whatsoever. In this study, the characterization of the physicochemical properties of the fruits in different stages of maturation is carried out. Analyzes of fresh weight (0.23g - 5.7g), longitudinal diameter (9.22 mm-26.2mm) and equatorial (6.18mm-23.6 mm), humidity (70%-85%), ash (0.012%-0.038%) were performed, pH (3.00-4.12), total soluble solids (6.2°Brix-2.2°Brix), total titratable acidity (1.7-23.9 mg of citric acid/g of fruit), finally classifying five states of maturation. In fruits with state of maturation of consumption, the mineral content was analyzed by atomic absorption spectrophotometry. It is concluded that the fruits of S. paniculatum have potential to be exploited for human consumption in Bogotá according to the physicochemical characteristics found and the content of phenols. It is suggested to carry out phytochemical analyzes that complement a study of the bioprospecting of the fruit. [ABSTRACT FROM AUTHOR]

Copyright of Revista ION is the property of Universidad Industrial de Santander and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)