387 results on '"Pollack, Gary M."'
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2. A Modified Team-Based Learning Physiology Course
3. Transforming a Large-Class Lecture Course to a Smaller-Group Interactive Course
4. Examination of the Ability of the Nasal Administration Route to Confer a Brain Exposure Advantage for Three Chemical Inhibitors of P-Glycoprotein
5. Pharmacokinetic analysis of trichloroethylene metabolism in male B6C3F1 mice: Formation and disposition of trichloroacetic acid, dichloroacetic acid, S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)- l-cysteine
6. Regional differences in capillary density, perfusion rate, and P-glycoprotein activity: A quantitative analysis of regional drug exposure in the brain
7. A Pharmacokinetic Model of Inhaled Methanol in Humans and Comparison to Methanol Disposition in Mice and Rats
8. The influence of distributional kinetics into a peripheral compartment on the pharmacokinetics of substrate partitioning between blood and brain tissue
9. Assessment of Blood–Brain Barrier Permeability Using the In Situ Mouse Brain Perfusion Technique
10. Opioid Tolerance Development: A Pharmacokinetic/Pharmacodynamic Perspective
11. Use of Tc-99m Mebrofenin as a Clinical Probe to Assess Altered Hepatobiliary Transport: Integration of In Vitro, Pharmacokinetic Modeling, and Simulation Studies
12. Kinetic Considerations for the Quantitative Assessment of Efflux Activity and Inhibition: Implications for Understanding and Predicting the Effects of Efflux Inhibition
13. Pharmacokinetics and Pharmacodynamics of Seven Opioids in P-Glycoprotein-Competent Mice: Assessment of Unbound Brain EC50,u and Correlation of in Vitro, Preclinical, and Clinical Data
14. Intestinal Absorptive Transport of the Hydrophilic Cation Ranitidine: A Kinetic Modeling Approach to Elucidate the Role of Uptake and Efflux Transporters and Paracellular vs. Transcellular Transport in Caco-2 Cells
15. Pharmacokinetics of Substrate Uptake and Distribution in Murine Brain After Nasal Instillation
16. Functional Evidence for P-glycoprotein at the Nose-Brain Barrier
17. Use of Loperamide as a Phenotypic Probe of mdr1a Status in CF-1 Mice
18. P-Glycoprotein Attenuates Brain Uptake of Substrates After Nasal Instillation
19. Indirect Analysis of Nitric Oxide and Quantitation of Selective Nitric Oxide Synthase Inhibitors in Microdialysate Samples
20. Hepatobiliary Disposition of a Drug/Metabolite Pair: Comprehensive Pharmacokinetic Modeling in Sandwich-Cultured Rat Hepatocytes
21. Pharmacokinetics and Pharmacodynamics of 7-Nitroindazole, a Selective Nitric Oxide Synthase Inhibitor, in the Rat Hippocampus
22. Effect of mdr1a P-Glycoprotein Gene Disruption, Gender, and Substrate Concentration on Brain Uptake of Selected Compounds
23. Pharmacokinetic and Pharmacodynamic Implications of P-Glycoprotein Modulation
24. Morphine Antinociception Is Enhanced in mdr1a Gene-Deficient Mice
25. Microdialysis Evaluation of the Ocular Pharmacokinetics of Propranolol in the Conscious Rabbit
26. Enhanced Antinociception of the Model Opioid Peptide [D-Penicillamine2,5] Enkephalin by P-Glycoprotein Modulation
27. Effect of GF120918, a Potent P-glycoprotein Inhibitor, on Morphine Pharmacokinetics and Pharmacodynamics in the Rat
28. Nasal Drug Administration: Potential for Targeted Central Nervous System Delivery
29. Training Clinical Pharmaceutical Scientists in Todayʼs Highly Competitive Times: Itʼs Time to Commit to Change
30. Neuronal nitric oxide modulates morphine antinociceptive tolerance by enhancing constitutive activity of the μ-opioid receptor
31. Hepatic Distribution and Clearance of Antisense Oligonucleotides in the Isolated Perfused Rat Liver
32. Extensive Biliary Excretion of the Model Opioid Peptide [D-PEN2,5] Enkephalin in Rats
33. Coordinated Nuclear Receptor Regulation of the Efflux Transporter, Mrp2, and the Phase-Ii Metabolizing Enzyme, GSTπ, at the Blood—Brain Barrier
34. Methanol Inhalation: Site and Other Factors Influencing Absorption, and an Inhalation Toxicokinetic Model for the Rat
35. A pharmacokinetic-pharmacodynamic model of tolerance to morphine analgesia during infusion in rats
36. Pharmacokinetics and Anticonvulsant Effect of a New Hypnotic, CL 284,846, in Rats
37. Age-Dependent Intestinal Absorption of Valproic Acid in the Rat
38. Assessment of Valproic Acid Serum–Cerebrospinal Fluid Transport by Microdialysis
39. Pharmacodynamics of morphine-induced neuronal nitric oxide production and antinociceptive tolerance development
40. The development of morphine antinociceptive tolerance in nitric oxide synthase-deficient mice
41. Variable modulation of opioid brain uptake by P-glycoprotein in mice
42. Use of a Pharmacokinetic Model Incorporating Discontinuous Gastrointestinal Absorption to Examine the Occurrence of Double Peaks in Oral Concentration–Time Profiles
43. Modelling the cardiovascular effects of ephedrine
44. Physiologic and metabolic influences on enterohepatic recirculation: Simulations based upon the disposition of valproic acid in the rat
45. Thermal Injury Decreases Hepatic Blood Flow and the Intrinsic Clearance of Indocyanine Green in the Rat
46. Acute Valproic Acid Overdose: Clinical Course and Pharmacokinetic Disposition of Valproic Acid and Metabolites
47. Contribution of Morphine-6-Glucuronide to Antinociception following Intravenous Administration of Morphine to Healthy Volunteers
48. Blood–Brain Barrier Efflux Transport
49. Pharmacokinetics and pharmacodynamics of l-arginine in rats: a model of stimulated neuronal nitric oxide synthesis
50. Development of an In Situ Mouse Brain Perfusion Model and Its Application to mdr1a P-Glycoprotein-Deficient Mice
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