30 results on '"Polucci, Paolo"'
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2. Supplementary Methods from NMS-E973, a Novel Synthetic Inhibitor of Hsp90 with Activity against Multiple Models of Drug Resistance to Targeted Agents, Including Intracranial Metastases
3. Supplementary Table S1 from NMS-E973, a Novel Synthetic Inhibitor of Hsp90 with Activity against Multiple Models of Drug Resistance to Targeted Agents, Including Intracranial Metastases
4. Fragment-based hit discovery and structure-based optimization of aminotriazoloquinazolines as novel Hsp90 inhibitors
5. Discovery of NMS-E973 as novel, selective and potent inhibitor of heat shock protein 90 (Hsp90)
6. A Molecular Anchor for Stabilizing Triple-Helical DNA
7. Binding free energy of selected anticancer compounds to DNA – theoretical calculations
8. Rational design, synthesis and biological evaluation of thiadiazinoacridines: A new class of antitumor agents
9. Abstract 4785: NMS-E668, a highly potent orally available RET inhibitor with selectivity towards VEGFR2 and demonstrated antitumor efficacy in multiple RET-driven cancer models
10. Abstract 2082: NMS-E668, a potent and selective RET kinase inhibitor characterized by specificity towards VEGFR2 and high antitumor efficacy against RET-driven models
11. Corrigendum to “Discovery of NMS-E973 as novel, selective and potent inhibitor of heat shock protein 90 (Hsp90)” [Bioorg. Med. Chem. 21 (2013) 7047–7063]
12. Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death
13. NMS-E973, a Novel Synthetic Inhibitor of Hsp90 with Activity against Multiple Models of Drug Resistance to Targeted Agents, Including Intracranial Metastases
14. Abstract 2091: Identification of a highly potent, selective and orally available RET inhibitor with antitumor efficacy in RET-dependent tumor models.
15. Alkylsulfanyl-1,2,4-triazoles, a New Class of Allosteric Valosine Containing Protein Inhibitors. Synthesis and Structure–Activity Relationships
16. Abstract 2940: Identification of potent VCP/p97/CDC48 inhibitors with distinct biochemical mechanisms including a reversible, allosteric inhibitor that activates the unfolded protein response, induce autophagy and cancer cell death
17. Benzodipyrazoles: a new class of potent CDK2 inhibitors
18. Catecholic Flavonoids Acting as Telomerase Inhibitors
19. Rational Design, Synthesis, and Biological Evaluation of Bis(pyrimido[5,6,1-de]acridines) and Bis(pyrazolo[3,4,5-kl]acridine-5-carboxamides) as New Anticancer Agents
20. Design, Synthesis, and Biological Properties of New Bis(acridine-4-carboxamides) as Anticancer Agents
21. 2,6-Di(ω-aminoalkyl)-2,5,6,7-tetrahydropyrazolo[3,4,5-mn]pyrimido[5,6,1-de]acridine-5,7-diones: Novel, Potent, Cytotoxic, and DNA-Binding Agents
22. Synthesis, Antitumor Cytotoxicity, and DNA-Binding of Novel N-5,2-Di(ω-aminoalkyl)-2,6-dihydropyrazolo[3,4,5-kl]acridine-5-carboxamides
23. ChemInform Abstract: N4-(ω-Aminoalkyl)-1- [(ω-aminoalkyl)amino]-4-acridinecarboxamides: Novel, Potent, Cytotoxic, and DNA-Binding Agents.
24. N4-(ω-Aminoalkyl)-1-[(ω-aminoalkyl)amino]-4-acridinecarboxamides: Novel, Potent, Cytotoxic, and DNA-Binding Agents
25. 2,3-Dihydro-1H,7H-pyrimido[5,6,1-de]acridine-1,3,7-trione Derivatives, a Class of Cytotoxic Agents Active on Multidrug-Resistant Cell Lines: Synthesis, Biological Evaluation, and Structure−Activity Relationships
26. 1,4- and 2,6-Disubstituted Amidoanthracene-9,10-dione Derivatives as Inhibitors of Human Telomerase
27. 1-[(ω-Aminoalkyl)amino]-4-[N-(ω-aminoalkyl)carbamoyl]-9-oxo-9,10-dihydro- acridines as Intercalating Cytotoxic Agents: Synthesis, DNA Binding, and Biological Evaluation
28. Synthesis of (Dialkylamino)alkyl-Disubstituted Pyrimido[5,6,1-de]acridines, a Novel Group of Anticancer Agents Active on a Multidrug Resistant Cell Line
29. Alkylsulfanyl-1,2,4-triazoles,a New Class of AllostericValosine Containing Protein Inhibitors. Synthesis and Structure–ActivityRelationships.
30. Benzodipyrazoles: a new class of potent CDK2 inhibitors.
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