1. Afferents of the mouse linear nucleus.
- Author
-
Liang H and Paxinos G
- Subjects
- Afferent Pathways, Amygdala cytology, Amygdala drug effects, Amygdala metabolism, Animals, Biotin pharmacology, Cerebellum drug effects, Cerebellum metabolism, Dorsal Raphe Nucleus cytology, Dorsal Raphe Nucleus metabolism, Medulla Oblongata metabolism, Mice, Mice, Inbred C57BL, Neural Pathways drug effects, Neural Pathways metabolism, Neurons cytology, Neurons metabolism, Pontine Tegmentum cytology, Pontine Tegmentum drug effects, Pontine Tegmentum metabolism, Trigeminal Nuclei cytology, Trigeminal Nuclei drug effects, Trigeminal Nuclei metabolism, Vestibular Nuclei cytology, Vestibular Nuclei drug effects, Vestibular Nuclei metabolism, Biotin analogs & derivatives, Dextrans pharmacology, Dorsal Raphe Nucleus drug effects, Neurons drug effects
- Abstract
The linear nucleus (Li) was identified in 1978 from its projections to the cerebellum. However, there is no systematic study of its connections with other areas of the central nervous system possibly due to the challenge of injecting retrograde tracers into this nucleus. The present study examines its afferents from some nuclei involved in motor and cardiovascular control with anterograde tracer injections. BDA injections into the central amygdaloid nucleus result in labeled fibers to the ipsilateral Li. Bilateral projections with an ipsilateral dominance were observed after injections in a) jointly the paralemniscal nucleus, the noradrenergic group 7/ Köllike -Fuse nucleus/subcoeruleus nucleus, b) the gigantocellular reticular nucleus, c) and the solitary nucleus/the parvicellular/intermediate reticular nucleus. Retrogradely labeled neurons were observed in Li after BDA injections into all these nuclei except the central amygdaloid and the paralemniscal nuclei. Our results suggest that Li is involved in a variety of physiological functions apart from motor and balance control it may exert via its cerebellar projections.
- Published
- 2020
- Full Text
- View/download PDF