4 results on '"Populatio"'
Search Results
2. Symptoms of gastroesophageal reflux and quality of life: population study
- Author
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O V Reshetnikov, S A Kurilovich, G I Simonova, E D Pylenkova, S K Maliutina, O G Gorbunova, and S N Bogatyrev
- Subjects
gastroesophageal reflux ,quality of life ,populatio ,Medicine - Abstract
Aim. To study prevalence of symptoms of gastroesophageal reflux (GER) in a free living population and to evaluate quality of life (QOL) in this disease. Material and methods. The gastroenterological symptoms and QOL were studied in a representative sample of adult population of 495 males and 548 females aged 45-70 years using a validated questionnaire, SF-36 questionnaire. Results. GER symptoms were seen in 17.0% responders, with the same frequency in men and women, in responders of different age. QOL was worse in responders with GER by 2 scales of SF-36 questionnaire: in males - "general well-being" and "viability", in females - “general well-being" and “physical functioning". In persons who had visited a doctor QOL was lower by all 8 scales than in those who had GER symptoms but had not visited a doctor. GER prevalence in Russia is similar to that in the West Europe and USA. QOL in GER patients is not low but worse in those who seek medical advice.
- Published
- 2008
3. Symptoms of gastroesophageal reflux and quality of life: population study
- Author
-
Reshetnikov, O. V., Kurilovich, S. A., Simonova, G. I., Pylenkova, E. D., Sofia Malyutina, Gorbunova, O. G., and Bogatyrev, S. N.
- Subjects
quality of life ,fungi ,gastroesophageal reflux ,lcsh:R ,lcsh:Medicine ,humanities ,populatio - Abstract
Aim. To study prevalence of symptoms of gastroesophageal reflux (GER) in a free living population and to evaluate quality of life (QOL) in this disease. Material and methods. The gastroenterological symptoms and QOL were studied in a representative sample of adult population of 495 males and 548 females aged 45-70 years using a validated questionnaire, SF-36 questionnaire. Results. GER symptoms were seen in 17.0% responders, with the same frequency in men and women, in responders of different age. QOL was worse in responders with GER by 2 scales of SF-36 questionnaire: in males - "general well-being" and "viability", in females - “general well-being" and “physical functioning". In persons who had visited a doctor QOL was lower by all 8 scales than in those who had GER symptoms but had not visited a doctor. GER prevalence in Russia is similar to that in the West Europe and USA. QOL in GER patients is not low but worse in those who seek medical advice.
- Published
- 2008
4. Twenty-five thousand years of fluctuating selection on leopard complex spotting and congenital night blindness in horses
- Author
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Gloria G. Fortes, Monika Reissmann, Rebecca R. Bellone, Norbert Benecke, Arturo Morales-Muñiz, Arne Ludwig, Edson Sandoval-Castellanos, Michael Hofreiter, Michael Cieslak, Mélanie Pruvost, Department of Evolutianory Genetics, Max-Planck-Institut-Leibniz Institute for Zoo and Wildlife Research Berlin (IZW), Department for Crop and Animal Sciences, Humboldt-Universität zu Berlin, Department of Natural Sciences, German Archaeological Institute (DAI), Department of Population Health and Reproduction and the Veterinary Genetics Laboratory, University of California [Davis] (UC Davis), University of California-University of California, Department of Bioinformatics and Genetics, SwedishMuseumof Natural History, Department of Biology, University of York [York, UK], UKInstituto Universitario de Xeología (IUX), Universitario de Xeología, Laboratory of Archaeozoology, Universidad Autonoma de Madrid (UAM), UKAdaptive and Evolutionary Genomics, University of Potsdam-Faculty of mathematics and natural sciences-Institute for Biochemistry and Biology, Institut Jacques Monod (IJM (UMR_7592)), Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), German Research Foundation (grant no. DFG LU 852/7-4), Humboldt Universität zu Berlin, and The German Archaeological Institute
- Subjects
0106 biological sciences ,Populatio ,History ,Eye Diseases ,DNA Mutational Analysis ,population ,01 natural sciences ,Medical and Health Sciences ,Gene Frequency ,Night Blindness ,Myopia ,History, Ancient ,Genetics ,Congenital stationary night blindness ,0303 health sciences ,education.field_of_study ,biology ,Fossils ,[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE] ,Part III: Animal and Crop Domestication ,Leopard ,Eye Diseases, Hereditary ,Genetic Diseases, X-Linked ,Single Nucleotide ,Biological Sciences ,Europe ,Hereditary ,Genetic Diseases ,Gene pool ,General Agricultural and Biological Sciences ,Medieval ,Population ,Molecular Sequence Data ,Zoology ,TRPM Cation Channels ,010603 evolutionary biology ,Polymorphism, Single Nucleotide ,General Biochemistry, Genetics and Molecular Biology ,Ancient ,03 medical and health sciences ,domestication ,Genetic ,biology.animal ,Animals ,Horses ,Allele ,Selection, Genetic ,Polymorphism ,Ancient DNA ,Coat colour ,Domestication ,Equus ,Palaeogenetics ,Base Sequence ,Bayes Theorem ,DNA ,DNA Primers ,Hair Color ,History, Medieval ,Horse Diseases ,Genetic Variation ,education ,Allele frequency ,Selection ,ancient DNA ,Institut für Biochemie und Biologie ,030304 developmental biology ,Evolutionary Biology ,Ambientale ,X-Linked ,biology.organism_classification ,palaeogenetics ,coat colour - Abstract
Leopard complex spotting is inherited by the incompletely dominant locus,LP, which also causes congenital stationary night blindness in homozygous horses. We investigated an associated single nucleotide polymorphism in theTRPM1gene in 96 archaeological bones from 31 localities from Late Pleistocene (approx. 17 000 YBP) to medieval times. The first genetic evidence ofLPspotting in Europe dates back to the Pleistocene. We tested for temporal changes in theLPassociated allele frequency and estimated coefficients of selection by means of approximate Bayesian computation analyses. Our results show that at least some of the observed frequency changes are congruent with shifts in artificial selection pressure for the leopard complex spotting phenotype. In early domestic horses from Kirklareli–Kanligecit (Turkey) dating to 2700–2200 BC, a remarkably high number of leopard spotted horses (six of 10 individuals) was detected including one adult homozygote. However,LPseems to have largely disappeared during the late Bronze Age, suggesting selection against this phenotype in early domestic horses. During the Iron Age,LPreappeared, probably by reintroduction into the domestic gene pool from wild animals. This picture of alternating selective regimes might explain how genetic diversity was maintained in domestic animals despite selection for specific traits at different times.
- Published
- 2015
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