Search

Your search keyword '"Pound D"' showing total 132 results
Start Over Author "Pound D"
132 results on '"Pound D"'

1. The importance of understanding the multiple dimensions of power in stakeholder participation for effective biodiversity conservation.

Author

Lécuyer, L., Balian, E., Butler, J. R. A., Barnaud, C., Calla, S., Locatelli, B., Newig, J., Pettit, J., Pound, D., Quétier, F., Salvatori, V., Von Korff, Y., and Young, J. C.

Subjects
SCIENTIFIC knowledge, BIODIVERSITY conservation, COMPUTER performance, POWER (Social sciences), STAKEHOLDER analysis
Abstract

Copyright of People & Nature is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024
Full Text
View/download PDF

3. Listening to young people’s views of the coast:Living Coast Youth Voice

Author

Pound, D, Larkins, Cath, and Pound, J

Subjects
L500
Abstract

We have summarised the knowledge that was co-created with young people here. However, we would like to encourage those adults who planned to read just this summary to also hear directly form the young people by reading Chapter 3.\ud \ud Introduction\ud Living Coast was a national partnership pilot project developed by Natural England1 (an organisation that looks after nature and landscapes in England). Natural England wants to help people from all walks-of-life enjoy the benefits of a new long distance path around England: the England Coast Path. By 2020, the path will stretch for approximately 2,700 miles around our beautiful English coastline and open up new stretches of the coastline. Natural England wants to understand how and why young people already use and enjoy the coast, and why others do not (or cannot). They want to know what can be done to help as many young people as possible benefit from the spectacular views, sea air, exercise and nature that the path and\ud surrounding areas offer.\ud In this research, we worked with young people aged 11 – 18 to create new knowledge about what makes it easy or hard for them to make the most of the coast, and what they suggest would help. This is important because there is little other evidence about this, nationally. This research took place in Barrow-in-Furness in Cumbria – a place with a high quality natural environment and areas that fall in the bottom 10% and 3% nationally on measures of deprivation. Cumbria was one of three Living Coast pilot areas in 2018/19. The other two are on the Durham Heritage Coast and the Solent. All three will inform how Natural England and its partners develop work at the coast.2\ud \ud Research focus\ud The study asked the following research questions:\ud Q What do you think of the coast?\ud Q How do you use the coast?\ud Q How do you benefit from the coast?\ud Q What makes it easy to go to, and enjoy, the coast?\ud Q What makes it hard to go to, and enjoy, the coast?\ud Q What would help you to go more often?\ud Q What suggestions would you make to Natural England about how they can help?\ud \ud Methods used\ud Our methods mixed and blended methods, techniques and principles from participation practice and\ud social science. \ud \ud To do this we: 2\ud \ud 1. In total, we met 59 young people from a mix of ages, genders, ethnicities, and distances from the coast, prioritising those who live in areas that fall in the lowest 3% or 10% in the Indices of Multiple Deprivation.\ud 2. Set up a Participatory Advisory Group (PAG) of eight young people, aged 14, to be our research advisors, comment on our methods and help us interpret and analyse our findings.\ud 3. Met with 47 young people in six groups, from a range of community and educational settings, for 90-minutes each. During these sessions, we worked with young people to create maps, discuss their good and bad experiences, ease of getting to the coast, and the influence of money, jobs, belonging and culture to their views of the coast.\ud 4. Summarised what young people said in this first round in pictures.\ud 5. Ran two ‘Creative Horizons’ events a fortnight later, in two sessions when 22 young people (of those who had taken part in the mapping sessions) were joined by 4 new young people. In these sessions young people took charge of which topics to explore and how to create new knowledge through art, story, rap, music, poems, drama, or discussion.\ud 6. Faithfully reported what young people said in this report and in a film.\ud Findings\ud We found that young people have a mix of attitudes towards the coast, with some finding it a place of enjoyment, peace, and adventure and others finding it boring, uncomfortable and a place of natural and human dangers. Young people go to a mix of places. Some are familiar beaches, which are closer to home and easier to get to, and others are destinations young people enjoy with friends and family but require transport to get to. Walking and dog walking were most often mentioned as activities to do at the coast, with some saying they swam in the sea but many others not mentioning swimming at all or saying they couldn’t swim. For a few, cycling was a key part of enjoying the coast and a couple of young people mentioned anglin g\ud and water sports.\ud Young people in all groups described psychological, physical and social wellbeing benefits of being by the sea. They said that it helped them cope with stress, be fitter and enjoy time with family and friends. The things that made it easier to go included: their own attitudes and confidence, being able to get there, having someone available to go with, feeling safe and belonging and also the time of year and the weather. The barriers to going to the seaside were numerous and interconnected and particularly hard for young people living with multiple pressures and disadvantages. Negative personal attitudes and fears included boredom and anxiety, such as about risks or body shaming. A range of issues around social\ud barriers included not feeling safe from attack, feeling they didn’t belong, that adults and peers were judging them badly as well as outright racism, sexism and homophobia. Young people also said they lacked information about where to go, how to get there, what to do once there, natural risks such as tides, quick sands and rock falls. Getting there and affording to go were practical barriers, as was having someone available to go with them. Litter and dirty beaches deter young people. At this exposed location, bad weather with fierce winds and driving rain can make it too unpleasant to go.\ud \ud Young peoples’ messages to the Natural England and its partners about enjoying the coast:\ud Help make it safe (from attack and by changing adult attitudes toward us)\ud \ud 3\ud Help us get there\ud Give us information\ud Provide affordable events and activities\ud Run nature trips\ud Provide shelters

Published
2019

4. Transforming knowledge systems for life on Earth : Visions of future systems and how to get there

Author

Fazey, I., Schäpke, N., Caniglia, G., Hodgson, A., Kendrick, I., Lyon, C., Page, G., Patterson, J., Riedy, C., Strasser, T., Verveen, S., Adams, D., Goldstein, B., Klaes, M., Leicester, G., Linyard, A., McCurdy, A., Ryan, P., Sharpe, B., Silvestri, G., Abdurrahim, A. Y., Abson, D., Adetunji, O. S., Aldunce, P., Alvarez-Pereira, C., Amparo, J. M., Amundsen, H., Anderson, L., Andersson, L., Asquith, M., Augenstein, K., Barrie, J., Bent, D., Bentz, J., Bergsten, A., Berzonsky, C., Bina, O., Blackstock, K., Boehnert, J., Bradbury, H., Brand, C., Böhme (born Sangmeister), J., Bøjer, M. M., Carmen, E., Charli-Joseph, L., Choudhury, S., Chunhachoti-ananta, S., Cockburn, J., Colvin, J., Connon, I. L. C., Cornforth, R., Cox, R. S., Cradock-Henry, N., Cramer, L., Cremaschi, A., Dannevig, H., Day, C. T., de Lima Hutchison, C., de Vrieze, A., Desai, V., Dolley, J., Duckett, D., Durrant, R. A., Egermann, M., Elsner (Adams), E., Fremantle, C., Fullwood-Thomas, J., Galafassi, D., Gobby, J., Golland, A., González-Padrón, S. K., Gram-Hanssen, I., Grandin, J., Grenni, S., Lauren Gunnell, J., Gusmao, F., Hamann, M., Harding, B., Harper, G., Hesselgren, M., Hestad, D., Heykoop, C. A., Holmén, J., Holstead, K., Hoolohan, C., Horcea-Milcu, A. -I, Horlings, L. G., Howden, S. M., Howell, R. A., Huque, S. I., Inturias Canedo, M. L., Iro, C. Y., Ives, C. D., John, B., Joshi, R., Juarez-Bourke, S., Juma, D. W., Karlsen, B. C., Kliem, L., Kläy, A., Kuenkel, P., Kunze, I., Lam, D. P. M., Lang, D. J., Larkin, A., Light, A., Luederitz, C., Luthe, T., Maguire, C., Mahecha-Groot, A. -M, Malcolm, J., Marshall, F., Maru, Y., McLachlan, C., Mmbando, P., Mohapatra, S., Moore, M. -L, Moriggi, A., Morley-Fletcher, M., Moser, S., Mueller, K. M., Mukute, M., Mühlemeier, S., Naess, L. O., Nieto-Romero, M., Novo, P., ÓBrien, K., O'Connell, D. A., O'Donnell, K., Olsson, Per, Pearson, K. R., Pereira, L., Petridis, P., Peukert, D., Phear, N., Pisters, S. R., Polsky, M., Pound, D., Preiser, R., Rahman, M. S., Reed, M. S., Revell, P., Rodriguez, I., Rogers, B. C., Rohr, J., Nordbø Rosenberg, M., Ross, H., Russell, S., Ryan, M., Saha, P., Schleicher, K., Schneider, F., Scoville-Simonds, M., Searle, B., Sebhatu, S. P., Sesana, E., Silverman, H., Singh, C., Sterling, E., Stewart, S. -J, Tàbara, J. D., Taylor, D., Thornton, P., Tribaldos, T. M., Tschakert, P., Uribe-Calvo, N., Waddell, S., Waddock, S., van der Merwe, L., van Mierlo, B., van Zwanenberg, P., Velarde, S. J., Washbourne, C. -L, Waylen, K., Weiser, A., Wight, I., Williams, S., Woods, M., Wolstenholme, R., Wright, N., Wunder, S., Wyllie, A., Young, H. R., Fazey, I., Schäpke, N., Caniglia, G., Hodgson, A., Kendrick, I., Lyon, C., Page, G., Patterson, J., Riedy, C., Strasser, T., Verveen, S., Adams, D., Goldstein, B., Klaes, M., Leicester, G., Linyard, A., McCurdy, A., Ryan, P., Sharpe, B., Silvestri, G., Abdurrahim, A. Y., Abson, D., Adetunji, O. S., Aldunce, P., Alvarez-Pereira, C., Amparo, J. M., Amundsen, H., Anderson, L., Andersson, L., Asquith, M., Augenstein, K., Barrie, J., Bent, D., Bentz, J., Bergsten, A., Berzonsky, C., Bina, O., Blackstock, K., Boehnert, J., Bradbury, H., Brand, C., Böhme (born Sangmeister), J., Bøjer, M. M., Carmen, E., Charli-Joseph, L., Choudhury, S., Chunhachoti-ananta, S., Cockburn, J., Colvin, J., Connon, I. L. C., Cornforth, R., Cox, R. S., Cradock-Henry, N., Cramer, L., Cremaschi, A., Dannevig, H., Day, C. T., de Lima Hutchison, C., de Vrieze, A., Desai, V., Dolley, J., Duckett, D., Durrant, R. A., Egermann, M., Elsner (Adams), E., Fremantle, C., Fullwood-Thomas, J., Galafassi, D., Gobby, J., Golland, A., González-Padrón, S. K., Gram-Hanssen, I., Grandin, J., Grenni, S., Lauren Gunnell, J., Gusmao, F., Hamann, M., Harding, B., Harper, G., Hesselgren, M., Hestad, D., Heykoop, C. A., Holmén, J., Holstead, K., Hoolohan, C., Horcea-Milcu, A. -I, Horlings, L. G., Howden, S. M., Howell, R. A., Huque, S. I., Inturias Canedo, M. L., Iro, C. Y., Ives, C. D., John, B., Joshi, R., Juarez-Bourke, S., Juma, D. W., Karlsen, B. C., Kliem, L., Kläy, A., Kuenkel, P., Kunze, I., Lam, D. P. M., Lang, D. J., Larkin, A., Light, A., Luederitz, C., Luthe, T., Maguire, C., Mahecha-Groot, A. -M, Malcolm, J., Marshall, F., Maru, Y., McLachlan, C., Mmbando, P., Mohapatra, S., Moore, M. -L, Moriggi, A., Morley-Fletcher, M., Moser, S., Mueller, K. M., Mukute, M., Mühlemeier, S., Naess, L. O., Nieto-Romero, M., Novo, P., ÓBrien, K., O'Connell, D. A., O'Donnell, K., Olsson, Per, Pearson, K. R., Pereira, L., Petridis, P., Peukert, D., Phear, N., Pisters, S. R., Polsky, M., Pound, D., Preiser, R., Rahman, M. S., Reed, M. S., Revell, P., Rodriguez, I., Rogers, B. C., Rohr, J., Nordbø Rosenberg, M., Ross, H., Russell, S., Ryan, M., Saha, P., Schleicher, K., Schneider, F., Scoville-Simonds, M., Searle, B., Sebhatu, S. P., Sesana, E., Silverman, H., Singh, C., Sterling, E., Stewart, S. -J, Tàbara, J. D., Taylor, D., Thornton, P., Tribaldos, T. M., Tschakert, P., Uribe-Calvo, N., Waddell, S., Waddock, S., van der Merwe, L., van Mierlo, B., van Zwanenberg, P., Velarde, S. J., Washbourne, C. -L, Waylen, K., Weiser, A., Wight, I., Williams, S., Woods, M., Wolstenholme, R., Wright, N., Wunder, S., Wyllie, A., and Young, H. R.

Abstract

Formalised knowledge systems, including universities and research institutes, are important for contemporary societies. They are, however, also arguably failing humanity when their impact is measured against the level of progress being made in stimulating the societal changes needed to address challenges like climate change. In this research we used a novel futures-oriented and participatory approach that asked what future envisioned knowledge systems might need to look like and how we might get there. Findings suggest that envisioned future systems will need to be much more collaborative, open, diverse, egalitarian, and able to work with values and systemic issues. They will also need to go beyond producing knowledge about our world to generating wisdom about how to act within it. To get to envisioned systems we will need to rapidly scale methodological innovations, connect innovators, and creatively accelerate learning about working with intractable challenges. We will also need to create new funding schemes, a global knowledge commons, and challenge deeply held assumptions. To genuinely be a creative force in supporting longevity of human and non-human life on our planet, the shift in knowledge systems will probably need to be at the scale of the enlightenment and speed of the scientific and technological revolution accompanying the second World War. This will require bold and strategic action from governments, scientists, civic society and sustained transformational intent.

Published
2020
Full Text
View/download PDF

5. Sustainable agriculture: Recognizing the potential of conflict as a positive driver for transformative change

Author

Bohan, D.A., Vanbergen, A.J., Skrimizea, E., Lecuyer, L., Bunnefeld, N., Butler, J.R.A., Fickel, T., Hodgson, I., Holtkamp, C., Marzano, M., Parra, C., Pereira, L., Petit, S., Pound, D., Rodríguez, I., Ryan, P., Staffler, J., Van den Broeck, P., Wittmer, Heidi, Young, J.C., Bohan, D.A., Vanbergen, A.J., Skrimizea, E., Lecuyer, L., Bunnefeld, N., Butler, J.R.A., Fickel, T., Hodgson, I., Holtkamp, C., Marzano, M., Parra, C., Pereira, L., Petit, S., Pound, D., Rodríguez, I., Ryan, P., Staffler, J., Van den Broeck, P., Wittmer, Heidi, and Young, J.C.

Abstract

Transformative changes in agriculture at multiple scales are needed to ensure sustainability, i.e. achieving food security while fostering social justice and environmental integrity. These transformations go beyond technological fixes and require fundamental changes in cognitive, relational, structural and functional aspects of agricultural systems. However, research on agricultural transformations fails to engage deeply with underlying social aspects such as differing perceptions of sustainability, uncertainties and ambiguities, politics of knowledge, power imbalances and deficits in democracy. In this paper, we suggest that conflict is one manifestation of such underlying social aspects. We present an original conceptualization and analytical framework, wherein conflict is recognized as an important motor for redistribution of power and leverage for social learning that—if addressed through a conflict transformation process—could potentially create a step-change in agricultural transformation towards greater sustainability. Our analysis, building on an extensive literature review and empirical case studies from around the world, suggests a novel approach to guide future transdisciplinary research that can support agricultural transformations towards sustainability.

Published
2020

10. Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial

Author

Kwo, PY, Lawitz, EJ, McCone, J, Schiff, ER, Vierling, JM, Pound, D, Davis, MN, Galati, JS, Gordon, SC, Ravendhran, N, Rossaro, L, Anderson, FH, Jacobson, IM, Rubin, R, Koury, K, Pedicone, LD, Brass, CA, Chaudhri, E, Albrecht, JK, CRAXI, Antonio, Kwo, PY, Lawitz, EJ, McCone, J, Schiff, ER, Vierling, JM, Pound, D, Davis, MN, Galati, JS, Gordon, SC, Ravendhran, N, Rossaro, L, Anderson, FH, Jacobson, IM, Rubin, R, Koury, K, Pedicone, LD, Brass, CA, Chaudhri, E, Albrecht, JK, and Craxi, A

Subjects
HCV
Published
2010

11. Effects of Ribavirin Dose Reduction vs Erythropoietin for Boceprevir-Related Anemia in Patients With Chronic Hepatitis C Virus Genotype 1 Infection—A Randomized Trial

Author

Poordad, Fred, Lawitz, Eric, Reddy, K. Rajender, Afdhal, Nezam, Hézode, Christophe, Zeuzem, Stefan, Lee, Samuel, Calleja, Jose Luis, Brown, Robert, Craxi, Antonio, Wedemeyer, Heiner, Nyberg, L. M., Nelson, David, Rossaro, Lorenzo, Balart, Luis, Morgan, Timothy, Bacon, Bruce, Flamm, Steven, Kowdley, Kris, Deng, Weiping, Koury, Kenneth, Pedicone, Lisa, Dutko, Frank, Burroughs, Margaret, Alves, Katia, Wahl, Janice, Brass, Clifford, Albrecht, Janice, Sulkowski, Mark, Bailey, R., Cooper, C., Feinman, S.V., Marotta, P., Tam, E., Wong, F., Bourlière, Marc, Bronowicki, Jean-Pierre, Hezode, Christophe, Tran, A., Goeser, Tobias, Klass, D., Schmid, R., Pirisi, M., Zuin, M., Bennett, M., Bernstein, D., Box, T., Boyer, T., Clain, D., Crippin, J., Davis, M., Felizarta, Franco, Freilich, Bradley, Galati, Joseph, Galler, G., Ghalib, Reem, Gibas, A., Godofsky, E., Gordon, F., Gordon, S., Gross, J., Harrison, S., Herrera, J., Herrine, S., Herring, R., Jacobson, I., Joshi, S., Kilby, A., King, J., Koch, A., Kowdley, Kris V, Kwo, P., Lebovics, E., Lee, W., Levin, J., Li, Xiaojian, Luketic, Velimir, Mailliard, M., Mccone, Jonathan, Mikolich, D., Muir, A., Mullen, K., Nunes, F., Nyberg, A., Pandya, P., Pauly, M., Peine, C., Poleynard, Gary, Poulos, J., Pound, D., Rabinovitz, M., Ravendhran, Natarajan, Reddy, R., Reindollar, Robert, Reuben, A., Riley, T., Rubin, R., Russo, M., Ryan, M., Saab, S., Santoro, J., Schmidt, W., Sepe, T., Sherman, K., Sjögren, Marketa, Slim, J., Smith, C., Stein, L., Strauss, R., Vargas, H., Vierling, John, Witt, D., Wu, G., Younes, Z., Texas Liver Institute [San Antonio], University of Texas Health Science Center, The University of Texas Health Science Center at Houston (UTHealth)- The University of Texas Health Science Center at Houston (UTHealth), Division of Gastroenterology (University of Pennsylvania), University of Pennsylvania [Philadelphia], Beth Israel Deaconess Medical Center, Harvard Medical School, Service d'hépato-gastro-entérologie [APHP Henri Mondor], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Johann Wolfgang Goethe University Medical Center, University of Calgary, University Hospital Puerta de Hierro, Madrid, New York Presbyterian Hospital, Università degli studi di Palermo - University of Palermo, Department of Gastroenterology, Hepatology and Endocrinology (MHH), Hannover Medical School [Hannover] (MHH), Kaiser Permanente, University of Florida [Gainesville] (UF), University of California [Davis] (UC Davis), University of California (UC), Tulane University Health Sciences Center, Veterans Affairs Long Beach Healthcare System (VA Long Beach Healthcare System), Saint Louis University School of Medicine [St Louis], Feinberg School of Medicine, Northwestern University [Evanston], Virginia Mason Medical Center, Merck & Co. Inc, Johns Hopkins University School of Medicine [Baltimore], Nutrition-Génétique et Exposition aux Risques Environnementaux (NGERE), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), and University of California

Subjects
Male, viruses, [SDV]Life Sciences [q-bio], Hepacivirus, medicine.disease_cause, Gastroenterology, Polyethylene Glycols, law.invention, chemistry.chemical_compound, 0302 clinical medicine, Randomized controlled trial, law, Erythropoiesis, Incidence, Disease Management, virus diseases, Anemia, Middle Aged, Recombinant Proteins, 3. Good health, Treatment Outcome, 030220 oncology & carcinogenesis, Drug Therapy, Combination, Female, 030211 gastroenterology & hepatology, Algorithms, medicine.drug, medicine.medical_specialty, Genotype, Proline, Side effect, Hepatitis C virus, Interferon alpha-2, Antiviral Agents, 03 medical and health sciences, Internal medicine, Boceprevir, Ribavirin, medicine, Humans, Erythropoietin, DAA, Dose-Response Relationship, Drug, Hepatology, business.industry, Interferon-alpha, Hepatitis C, Chronic, biochemical phenomena, metabolism, and nutrition, medicine.disease, digestive system diseases, Side Effect, Logistic Models, chemistry, Immunology, Hemoglobin, business, EPO
Abstract

International audience; Background & AimsTreatment of hepatitis C virus (HCV) infection with boceprevir, peginterferon, and ribavirin can lead to anemia, which has been managed by reducing ribavirin dose and/or erythropoietin therapy. We assessed the effects of these anemia management strategies on rates of sustained virologic response (SVR) and safety.MethodsPatients (n = 687) received 4 weeks of peginterferon and ribavirin followed by 24 or 44 weeks of boceprevir (800 mg, 3 times each day) plus peginterferon and ribavirin. Patients who became anemic (levels of hemoglobin approximately ≤10 g/dL) during the study treatment period (n = 500) were assigned to groups that were managed by ribavirin dosage reduction (n = 249) or erythropoietin therapy (n = 251).ResultsRates of SVR were comparable between patients whose anemia was managed by ribavirin dosage reduction (71.5%) vs erythropoietin therapy (70.9%), regardless of the timing of the first intervention to manage anemia or the magnitude of ribavirin dosage reduction. There was a threshold for the effect on rate of SVR: patients who received

Published
2013
Full Text
View/download PDF

12. High Efficacy of Sofosbuvir/Velpatasvir Plus GS-9857 for 12 Weeks in Treatment-Experienced Genotype 1-6 HCV-Infected Patients, Including Those Previously Treated with Direct-Acting Antivirals

Author

Lawitz, E., primary, Kowdley, K., additional, Curry, M., additional, Reau, N., additional, Nguyen, M., additional, Kwo, P., additional, Jacobson, I., additional, Tran, T.T., additional, Nahass, R., additional, Hinestrosa, F., additional, Herring, R., additional, Bennet, M., additional, Yang, J.C., additional, Stamm, L.M., additional, An, Di, additional, Dvory-Sobol, H., additional, Brainard, D.M., additional, McHutchison, J.G., additional, Schiff, E., additional, Davis, M., additional, Etzkorn, K., additional, Chung, R.T., additional, Pound, D., additional, Rodriguez-Torres, M., additional, Reddy, K.R., additional, Younes, Z., additional, and Gane, E.J., additional

Published
2016
Full Text
View/download PDF

13. O56 SOFOSBUVIR/LEDIPASVIR WITH AND WITHOUT RIBAVIRIN FOR 8 WEEKS COMPARED TO SOFOSBUVIR/LEDIPASVIR FOR 12 WEEKS IN TREATMENT-NAÏVE NON-CIRRHOTIC GENOTYPE-1 HCV-INFECTED PATIENTS: THE PHASE 3 ION-3 STUDY

Author

Kowdley, K.V., primary, Stuart, G.C., additional, Reddy, R.K., additional, Rossaro, L., additional, Bernstein, D.E., additional, An, D., additional, Svarovskaia, E.S., additional, Hyland, R.H., additional, Pang, P.S., additional, Symonds, W.T., additional, Mchutchison, J.G., additional, Muir, A.J., additional, Pockros, P.J., additional, Pound, D., additional, and Fried, M.W., additional

Published
2014
Full Text
View/download PDF

14. PS008 - High Efficacy of Sofosbuvir/Velpatasvir Plus GS-9857 for 12 Weeks in Treatment-Experienced Genotype 1-6 HCV-Infected Patients, Including Those Previously Treated with Direct-Acting Antivirals

Author

Lawitz, E., Kowdley, K., Curry, M., Reau, N., Nguyen, M., Kwo, P., Jacobson, I., Tran, T.T., Nahass, R., Hinestrosa, F., Herring, R., Jr., Bennet, M., Yang, J.C., Stamm, L.M., An, Di, Dvory-Sobol, H., Brainard, D.M., McHutchison, J.G., Schiff, E., Davis, M., Etzkorn, K., Chung, R.T., Pound, D., Rodriguez-Torres, M., Reddy, K.R., Younes, Z., and Gane, E.J.

Published
2016
Full Text
View/download PDF

16. 2016 LONG-TERM OUTCOMES FOLLOWING COMBINATION TREATMENT WITH BOCEPREVIR PLUS PEG-INTRON/RIBAVIRIN (P/R) IN PATIENTS WITH CHRONIC HEPATITIS C, GENOTYPE 1 (CHC-G1)

Author

Vierling, J.M., primary, Ralston, R., additional, Lawitz, E.J., additional, McCone, J., additional, Gordon, S., additional, Pound, D., additional, Davis, M., additional, Galati, J., additional, Jacobson, I., additional, Rossaro, L., additional, Anderson, F.H., additional, King, J., additional, Cassidy, W., additional, Bourliere, M., additional, Esteban-Mur, R., additional, Ravendhran, N., additional, Galler, G., additional, Mendez, P., additional, Brass, C.A., additional, and Albrecht, J.K., additional

Published
2010
Full Text
View/download PDF

17. 4 HCV SPRINT-1 FINAL RESULTS: SVR 24 FROM A PHASE 2 STUDY OF BOCEPREVIR PLUS PEGINTRON™ (PEGINTERFERON ALFA-2B)/RIBAVIRIN IN TREATMENT- NAIVE SUBJECTS WITH GENOTYPE-1 CHRONIC HEPATITIS C

Author

Kwo, P., primary, Lawitz, E., additional, McCone, J., additional, Schiff, E., additional, Vierling, J., additional, Pound, D., additional, Davis, M., additional, Galati, J., additional, Gordon, S., additional, Ravendhran, N., additional, Rossaro, L., additional, Anderson, F., additional, Jacobson, I., additional, Rubin, R., additional, Koury, K., additional, Brass, C., additional, Chaudhri, E., additional, and Albrecht, J., additional

Published
2009
Full Text
View/download PDF

18. 995 INTERIM RESULTS FROM HCV SPRINT-1: RVR/EVR FROM PHASE 2 STUDY OF BOCEPREVIR PLUS PEGINTRONTM (PEGINTERFERON ALFA-2B)/RIBAVIRIN IN TREATMENT-NAIVE SUBJECTS WITH GENOTYPE-1 CHC

Author

Kwo, P., primary, Lawitz, E., additional, McCone, J., additional, Schiff, E., additional, Vierling, J., additional, Pound, D., additional, Davis, M., additional, Galati, J., additional, Gordon, S., additional, Ravendhran, N., additional, Rossaro, L., additional, Anderson, F., additional, Jacobson, I., additional, Rubin, R., additional, Mukhopadhyay, P., additional, Chaudhri, E., additional, Pedicone, L., additional, and Albrecht, J., additional

Published
2008
Full Text
View/download PDF

24. Comparison of three nonsurgical treatments for bleeding esophageal varices

Author

O'Connor, K.W., Lehman, G., Yune, H., Brunelle, R., Christiansen, P., Hast, J., Compton, M., McHenry, R., Klatte, E., Cockerill, E., Holden, R., Becker, G., Kopecky, K., Hawes, R., Pound, D., Rex, D., Lui, A., Snodgrass, P., Weddle, R., Crabb, D., and Lumeng, L.

Abstract

Ninety-seven patients with recent or active variceal bleeding were randomly assigned to oral propranolol, endoscopic sclerotherapy plus oral propranolol, or transhepatic sclerotherapy plus oral propranolol. The effects of treatment on the number of units transfused, rebleeding of any magnitude, major rebleeding, and death were assessed in these patients, 82% of whom were alcoholic and 81% Child's Class C. After a minimum follow-up interval of 2 yr (range, 27–65 mo), major rebleeding rates were 65% for propranolol alone, 45% for endoscopic sclerotherapy plus propranolol, and 60% for transhepatic sclerotherapy plus propranolol. The corresponding death rates were 81% for propranolol alone, 55% for endoscopic sclerotherapy plus propranolol, and 66% for transhepatic sclerotherapy plus propranolol (p = 0.03). Thirty-three patients (34%) never received propranolol: 8 due to medical contraindications and 25 because they died or bled enough to meet the definition of treatment failure within 3 or 4 days of randomizations (no significant differences among treatment groups). Patients assigned to propranolol alone bled sooner, bled more units, and had a higher mortality rate than patients treated by endoscopic sclerotherapy plus propranolol. Patients treated with transhepatic sclerotherapy plus propranolol had intermediate results. Propranolol alone is inadequate treatment for esophageal variceal bleeding in patients with advanced liver disease.

Published
1989
Full Text
View/download PDF

25. PERSONAL CARE

Author

Pound, D. P. B.

Subjects
Letters to the Editor
Published
1980

33. The Earl of Shaftesbury

Author

Mayall, John Jabez Edwin, Pound, D. J., Mayall, John Jabez Edwin, and Pound, D. J.

Catalog

Books, media, physical & digital resources
See catalog results