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Your search keyword '"Pouw, R.E. (R. E.)"' showing total 2 results
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2 results on '"Pouw, R.E. (R. E.)"'

1. Adherence to pre-set benchmark quality criteria to qualify as expert assessor of dysplasia in Barrett’s esophagus biopsies – towards digital review of Barrett’s esophagus

Author

van der Wel, M.J. (M. J.), Klaver, E. (E.), Duits, L.C. (L. C.), Pouw, R.E. (R. E.), Seldenrijk, K.A. (Kees), Offerhaus, G.J.A. (Johan), Visser, M. (Marjan), ten Kate, F.J.W. (F. J.W.), Biermann, K. (Katharina), Brosens, L.A. (Lodewijk), Doukas, M. (M.), Huysentruyt, C.J. (Clément J.), Karrenbeld, A. (A.), Kats-Ugurlu, G. (Gursah), van der Laan, J.S. (J. S.), Lijnschoten, G. van, Moll, F.C.P., Ooms, A.H.A.G. (Ariadne), Tijssen, J.G.P. (Jan), Bergman, J.J.G.H.M. (Jacques), Meijer, S.L. (Sybren), van der Wel, M.J. (M. J.), Klaver, E. (E.), Duits, L.C. (L. C.), Pouw, R.E. (R. E.), Seldenrijk, K.A. (Kees), Offerhaus, G.J.A. (Johan), Visser, M. (Marjan), ten Kate, F.J.W. (F. J.W.), Biermann, K. (Katharina), Brosens, L.A. (Lodewijk), Doukas, M. (M.), Huysentruyt, C.J. (Clément J.), Karrenbeld, A. (A.), Kats-Ugurlu, G. (Gursah), van der Laan, J.S. (J. S.), Lijnschoten, G. van, Moll, F.C.P., Ooms, A.H.A.G. (Ariadne), Tijssen, J.G.P. (Jan), Bergman, J.J.G.H.M. (Jacques), and Meijer, S.L. (Sybren)

Abstract

Background: Dysplasia assessment of Barrett’s esophagus biopsies is associated with low observer agreement; guidelines advise expert review. We have developed a web-based review panel for dysplastic Barrett’s esophagus biopsies. Objective: The purpose of this study was to test if 10 gastrointestinal pathologists working at Dutch Barrett’s esophagus expert centres met pre-set benchmark scores for quality criteria. Methods: Ten gastrointestinal pathologists twice assessed 60 digitalized Barrett’s esophagus cases, enriched for dysplasia; then r

Published
2019
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2. A single-step sizing and radiofrequency ablation catheter for circumferential ablation of Barrett's esophagus: Results of a pilot study

Author

Belghazi, K. (K.), Pouw, R.E. (R. E.), Sondermeijer, C.M.T. (C. M.T.), Meijer, S.L. (Sybren), Schoon, E.J. (Erik), Koch, A.D. (Arjun), Weusten, B.L. (Bas), Bergman, J.J.G.H.M. (Jacques), Belghazi, K. (K.), Pouw, R.E. (R. E.), Sondermeijer, C.M.T. (C. M.T.), Meijer, S.L. (Sybren), Schoon, E.J. (Erik), Koch, A.D. (Arjun), Weusten, B.L. (Bas), and Bergman, J.J.G.H.M. (Jacques)

Abstract

Background: The 360 Express balloon catheter (360 Express) has the ability to self-adjust to the esophageal lumen, ensuring optimal tissue contact. Objective: The objective of this article is to evaluate the efficacy and safety of the 360 Express for radiofrequency ablation (RFA) treatment of Barrett's esophagus (BE). Methods: BE patients with low-grade dysplasia (LGD), high-grade dysplasia (HGD) or early cancer (EC) were included. Visible lesions were removed by endoscopic resection (ER) prior to RFA. RFA was performed with the 360 Express using the standard ablation regimen (12J/cm2–clean–12J/cm2). Primary outcome: BE regression percentage at three months. Secondary outcomes: procedure time, adverse events, complete eradication of dysplasia (CE-D) and intestinal metaplasia (CE-IM). Results: Thirty patients (median BE C4M6) were included. Eight patients underwent ER prior to RFA. Median BE regression: 90%. Median procedure time: 31 minutes. Adverse events (13%): laceration (n = 1); atrial fibrillation (n = 1); vomiting and dysphagia (n = 1); dysregulated diabetes (n = 1). After subsequent treatment CE-D and CE-IM was achieved in 97% and 87%, respectively. In 10% a stenosis developed during additional treatment requiring a median of one dilation. Conclusion: This study shows that circumferential RFA using the 360 Express may shorten procedure time, while maintaining efficacy compared to standard circumferential RFA.

Published
2018
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