13 results on '"Prabhat Khakural"'
Search Results
2. Ruptured Corpus Luteum among Women Undergoing Laparotomy for Hemoperitoneum in a Tertiary Care Centre: A Descriptive Cross-sectional Study
- Author
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Pooja Paudyal, Suniti Joshi Rawal, and Prabhat Khakural
- Subjects
anticoagulant ,corpus luteum ,hemoperitoneum. ,Medicine (General) ,R5-920 - Abstract
Introduction: Rupture of the corpus luteum, though generally self-limiting in women with normal coagulation, could lead to life-threatening bleeding in patients with prosthetic valves on anticoagulant therapy and described in only a few case reports in the literature. The aim of this study was to find out the prevalence of ruptured corpus luteum among women undergoing laparotomy for hemoperitoneum in a tertiary care centre. Methods: This descriptive cross-sectional study was conducted among women undergoing laparotomy for hemoperitoneum in a tertiary centre from 7 April 2017 to 31 March 2021 after obtaining ethical approval from the Institutional Review Committee [Reference number: 328(6-11-E)2/73/74]. All women who underwent laparotomy for hemoperitoneum during the study period were enrolled. Convenience sampling technique was used. Point estimate and 95% Confidence Interval were calculated. Results: Out of 447 women who underwent laparotomy for hemoperitoneum, ruptured corpus luteum was seen in 48 (10.74%) (7.87-13.61, 95% Confidence Interval). Out of which 36 (75%) had prosthetic valves. There was 1 (2.77%) mortality and 3 (8.33%) recurrences. Conclusions: The prevalence of rupture of the corpus luteum among women undergoing laparotomy for hemoperitoneum was similar to other studies done in similar settings. Early diagnosis, emergent reversal of coagulopathy and surgery if needed are the mainstay of management.
- Published
- 2023
3. Cardiac Myxoma among Patients Undergoing Cardiac Surgery in a Tertiary Care Center: A Descriptive Cross-sectional Study
- Author
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Prabhat Khakural, Ravi Baral, Anil Bhattarai, and Bhagawan Koirala
- Subjects
embolism ,heart neoplasms ,myxoma ,Medicine (General) ,R5-920 - Abstract
Introduction: Heart neoplasms are rare tumors. Myxoma is the commonest primary benign tumor of the heart presenting with features of obstruction, arrhythmia, and embolism. Surgical excision of the tumor is the gold standard of treatment. The aim of the study is to find out the prevalence of cardiac myxoma among all cardiac surgeries operated during the study period. Methods: A descriptive cross-sectional study was done among 3800 patients undergoing surgery for cardiac tumors in a tertiary care center after obtaining approval from the Institutional Review Committee (Reference number- 36/(6-11)E2/077/078). The data was collected retrospectively from August 2012 to August 2020 using convenience sampling method. Statistical analysis was performed using Microsoft Excel 2016. Point estimate at 95% Confidence Interval was calculated along with frequency, percentage, mean and standard deviation. Results: There were 26 (0.68%) (0.42-0.94 at 95% Confidence Interval) myxoma among 3800 cardiac surgeries performed over eight years. The mean age of the patients was 54.76±14.31 (range 17-75) years. Twenty (76.92%) patients were females. The commonest presenting symptom was shortness of breath in 19 (73.07%) patients. En masse excision with the closure of the atrial septal defect was the principal surgical technique. The mean Intensive Care Unit stay and hospital stays were 2.92±1.29 and 6.26±2.61 days respectively. There was no perioperative mortality. Conclusions: Cardiac myxoma was the most common cardiac tumor encountered as in other studies.
- Published
- 2022
4. Outcome of diaphragmatic herniation and eventration repair in adults
- Author
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Prabhat Khakural, R Sapkota, and P Sayami
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Diaphragmatic hernia ,Eventration ,Morgagni hernia ,Surgery ,RD1-811 - Abstract
Introduction: Diaphragmatic hernia and eventration are amongst the less commonly encountered thoracic surgical problems in Nepal. Unlike, the cases of traumatic herniation, adults with congenital hermination and eventration seek medical attention very late. Methods: It is a retrospective observational study of patients presenting with diaphragmatic hermiation and eventration at Manmohan Cardiothoracic Vascular and Transplant Center, Kathmandu, Nepal. Medical records of five years (May, 2010 to April, 2015) were reviewed. Analysis of the demographic profile, clinical features, management and outcome was done. Results: There were a total of 15 patients who were diagnosed to have diaphragmatic hermiation and eventration. There were eight cases of hermiation and seven cases of eventration. There were three cases of acute diaphragmatic hermiation. Thoracic trauma was found to be associated in three cases of herniation only. The mean age at presentation was 46.5 years. Thoracic trauma was seen in Younger age (mean age being 34 yrs). There were two cases of morgagni hernia and one of these was diagnosed incidentally. Mean duration of symptoms was two months. The most common presenting symptoms were shortness of breath and cough. Twelve cases were repaired via thoracotomy. Mean size of diaphragmatic defect was six centimeters. The most commonly herniated organ was stomach followed by momentum. Placation was the most commonly performed procedure in eventration and primary repair was done in six cases of hermiation and mesh repair in two cases. Only two patients had superficial surgical site infection. Mean duration of hospital stay was eight days. The patients were doing good up to mean follow up period of four months. Conclusion: Diaphragmatic hermiation and eventration in symptomatic patients should be managed surgically. Surgical approaches can be thoracotomy, laparotomy and Video Assisted Thoracoscopic Surgery. Outcome following surgery is good with minimal postoperative complications. JSSN 2015; 18 (1), Page : 1-4
- Published
- 2017
- Full Text
- View/download PDF
5. Amplatzer atrial septal defect occluder device embolisation to right pulmonary artery
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Prabhat Khakural, Ravi Baral, Anil Bhattarai, and Bhagawan Koirala
- Abstract
Atrial septal defect is a common congenital acyanotic heart disease which is treated with either surgical closure or transcatheter closure. Although surgical closure is gold standard, transcatheter device closure is gaining popularity worldwide and in Nepal due to favourable outcome in selected patients. Device migration following transvenous closure of atrial septal defect is a common problem but its lodgment in right pulmonary artery is a rarely encountered and reported clinical scenario. Here, the authors report a case of 42-year-old female who had an embolisation of Amplatzer septal occluder to right pulmonary artery requiring urgent surgical intervention to retrieve the device.
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- 2022
- Full Text
- View/download PDF
6. Spectrum of coronary anomalies and their categorical approach: rare case series
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Krishnaprasad Bashyal, Bhagawan Koirala, Anil Bhattarai, Ravi Kumar Baral, Prabhat Khakural, Samir Shakya, and Prashiddha Bikram Kadel
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Surgery - Abstract
The incidence of coronary artery anomalies (CAAs) is 0.2–1.2% of the population. Its paradox of being a rare entity with presentation ranging from sudden cardiac death, congestive heart failure, myocardial infarction to being clinically silent, asserts a challenge to its treating physician. Among the various major categories of CAA, we describe four different types of these anomalies in our retrospective evaluation over 2 years. They include – coronary cameral fistula with coronary aneurysm, congenital atresia of left main, anomalous aortic origin of left anterior descending (LAD) and circumflex artery (LCx) with malignant LAD course, anomalous origin of left coronary artery from pulmonary artery (ALCAPA). Although the child with ALCAPA succumbed despite every possible and available timely efforts, other patients had good postoperative recovery and a brief hospital stay.
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- 2022
- Full Text
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7. Atrial Septal Defect Closure Via Mini Thoracotomy and with Peripheral Cannulation
- Author
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Anil, Bhattarai, Basanta, Sharma Paudel, Sangam, Shah, Apsara, Pandey, Prabhat, Khakural, Ravi, Baral, Kalanath, Thapaliya, and Bhagawan, Koirala
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Male ,Cross-Sectional Studies ,Treatment Outcome ,Nepal ,Thoracotomy ,Humans ,Minimally Invasive Surgical Procedures ,Female ,Heart Septal Defects, Atrial ,Catheterization ,Retrospective Studies - Abstract
Atrial septal defect is one of the most common congenital cardiac disorders requiring intervention. We compared a minimally invasive method for atrial septal defect closure that included total peripheral cannulation and an anterior mini-thoracotomy incision of 5 cm or less with a median sternotomy approach.This was a retrospective cross-sectional study among patients with Atrial Septal Defect. The preoperative variables, intraoperative data, and postoperative outcomes of patients undergoing minimally invasive atrial septal defect closure with total peripheral cannulation and atrial septal defect closure via median sternotomy were collected and compared.Fifty-five patients underwent minimally invasive closure of the atrial septal defect with total peripheral cannulation and 55 patients that underwent surgery by median sternotomy were included for comparison. There were 61.81% (34) female and 38.18% (21) male in the mini-thoracotomy group while there were 52.72% (29) female and 47.27% (26) male in the median sternotomy group. The mean age at surgery was 23.4 and 28.6 years in mini-thoracotomy and median sternotomy groups of patients respectively. The most common symptom was exertional shortness of breath in both groups. The mean length of stay in the intensive care unit was 1.8 and 2.5 days in mini-thoracotomy and median sternotomy groups respectively, and the length of stay in the hospital was 4.5 days and 4.8 days in mini-thoracotomy and median sternotomy groups respectively. There was a significant association was found between the mini-thoracotomy and median sternotomy group in relation to mean size of the incision, average time for cardiopulmonary bypass, average cross-clamp time, and fluid drained on the first day after surgery.Atrial septal defect closure with a mini-invasive approach is safe and cost-effective with very few perioperative complications and good patient satisfaction.
- Published
- 2021
8. Atrial Septal Defect Closure by Anterior Mini Thoracotomy with Total Peripheral Cannulation: A Step towards Establishing Mini Invasive Cardiac Surgery in a Developing Nation
- Author
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Bhagawan Koirala, Anil Bhattarai, Ravi Kumar Baral, and Prabhat Khakural
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medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,Intensive care unit ,Surgery ,Peripheral ,Cardiac surgery ,law.invention ,Aortic cross-clamp ,Median sternotomy ,law ,Breathing ,Medicine ,business ,Complication ,Prospective cohort study - Abstract
Background: Atrial Septal Defect (ASD) closure is a common cardiac surgical procedure performed worldwide. Due to favourable clinical outcome, minimal invasive approach is becoming popular. Hence this study was conducted to compare the outcome of two surgical approaches, median sternotomy and mini thoracotomy with total peripheral cannulation, in a developing country Nepal. Methods: A prospective study of 62 ASD patients, randomized to undergo surgical closure either via right anterior mini thoracotomy or median sternotomy was conducted and followed up over three years. The clinical outcome parameters like intensive care unit stay, hospital stay, post-operative duration of ventilation, cardiopulmonary bypass time, aortic cross clamp time, mediastinal drainage, size of scar and complication were compared between two groups. Results: Cardiopulmonary bypass time and aortic cross clamp time were significantly longer in right anterior mini thoracotomy group as compared to median sternotomy group (43.97 min ± 12.70 min vs 34.42 min ± 10.42 min and 25.13 min ± 7.82 min vs 19.48 min ± 6.93 min respectively, p-value 0.05). There was no significant difference in duration of surgery (2.75 hrs ± 0.43 hrs vs 2.56 hrs ± 0.41 hrs, p-value = 0.09), post-operative ventilation (2.90 hrs ± 1.22 hrs and 2.88 hrs ± 1.07 hrs, p-value = 0.96) between two groups. Post-operative mediastinal drainage was significantly less in right anterior mini thoracotomy group (214.52 ml ± 91.79 ml vs 284.03 ml ± 158.91 ml, p-value = 0.04). There was no significant difference in ICU stay and hospital stay. Conclusion: Atrial septal defect can be safely closed by right anterior mini thoracotomy with a small, cosmetically acceptable submammary scar with less pain and bleeding.
- Published
- 2020
- Full Text
- View/download PDF
9. Challenges in Managing Pregnancy with Complete Heart Block and Its Outcome in a Tertiary Center in Nepal
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Pooja Paudyal, Suniti Rawal, and Prabhat Khakural
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Pregnancy ,medicine.medical_specialty ,Heart block ,business.industry ,Emergency medicine ,medicine ,Obstetrics and Gynecology ,Center (algebra and category theory) ,medicine.disease ,business ,Outcome (game theory) - Published
- 2020
- Full Text
- View/download PDF
10. An unusual penetrating shrapnel in the heart
- Author
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Anil Bhattarai, Ravi Kumar Baral, Bhagawan Koirala, and Prabhat Khakural
- Subjects
Pulmonary and Respiratory Medicine ,Adult ,Male ,medicine.medical_specialty ,business.industry ,Heart Ventricles ,Wounds, Penetrating ,General Medicine ,Foreign Bodies ,Surgery ,Young Adult ,Treatment Outcome ,Heart Injuries ,Penetration (warfare) ,Medicine ,Humans ,Surgical emergency ,Cardiology and Cardiovascular Medicine ,business - Abstract
Penetrating heart trauma is a surgical emergency and can be fatal. However, cardiac penetration occurring due to non-explosive shrapnel is a rare occurrence. We report a case of a 20-year-old man, who sustained a laceration in his left chest, while he was breaking a rock with a chisel and a hammer. He was diagnosed to have an intramyocardial foreign body in his left ventricle. He underwent left ventriculotomy, foreign body localization under fluoroscopic guidance and successful extraction of the shrapnel from the left ventricular cavity.
- Published
- 2021
11. Outcome of diaphragmatic herniation and eventration repair in adults
- Author
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Ranjan Sapkota, Prakash Sayami, and Prabhat Khakural
- Subjects
medicine.medical_specialty ,Diaphragmatic hernia ,RD1-811 ,business.industry ,medicine.medical_treatment ,Medical record ,Diaphragmatic breathing ,Retrospective cohort study ,Eventration ,medicine.disease ,Surgery ,Laparotomy ,Video-assisted thoracoscopic surgery ,medicine ,Morgagni hernia ,Hernia ,Thoracotomy ,business - Abstract
Introduction: Diaphragmatic hernia and eventration are amongst the less commonly encountered thoracic surgical problems in Nepal. Unlike, the cases of traumatic herniation, adults with congenital hermination and eventration seek medical attention very late.Methods: It is a retrospective observational study of patients presenting with diaphragmatic hermiation and eventration at Manmohan Cardiothoracic Vascular and Transplant Center, Kathmandu, Nepal. Medical records of five years (May, 2010 to April, 2015) were reviewed. Analysis of the demographic profile, clinical features, management and outcome was done.Results: There were a total of 15 patients who were diagnosed to have diaphragmatic hermiation and eventration. There were eight cases of hermiation and seven cases of eventration. There were three cases of acute diaphragmatic hermiation. Thoracic trauma was found to be associated in three cases of herniation only. The mean age at presentation was 46.5 years. Thoracic trauma was seen in Younger age (mean age being 34 yrs). There were two cases of morgagni hernia and one of these was diagnosed incidentally. Mean duration of symptoms was two months. The most common presenting symptoms were shortness of breath and cough. Twelve cases were repaired via thoracotomy. Mean size of diaphragmatic defect was six centimeters. The most commonly herniated organ was stomach followed by momentum. Placation was the most commonly performed procedure in eventration and primary repair was done in six cases of hermiation and mesh repair in two cases. Only two patients had superficial surgical site infection. Mean duration of hospital stay was eight days. The patients were doing good up to mean follow up period of four months.Conclusion: Diaphragmatic hermiation and eventration in symptomatic patients should be managed surgically. Surgical approaches can be thoracotomy, laparotomy and Video Assisted Thoracoscopic Surgery. Outcome following surgery is good with minimal postoperative complications. JSSN 2015; 18 (1), Page : 1-4
- Published
- 2017
12. An unusual case of pulmonary embolism
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Kajan Raj Shrestha, Uttam Krishna Shrestha, Prabhat Khakural, and Ranjan Sapkota
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medicine.medical_specialty ,Chemotherapy ,Tuberculosis ,business.industry ,medicine.medical_treatment ,Case Reports ,medicine.disease ,Chemotherapy regimen ,Pulmonary embolism ,Surgery ,Pneumonia ,Embolus ,Embolism ,medicine ,Radiology ,Differential diagnosis ,business - Abstract
Pulmonary embolism carries a significant morbidity and mortality. Metastatic choriocarcinoma presenting as pulmonary embolism is a rare event. Here, we report a case of a 25-year-lady with a history of worsening shortness of breath for 4 months who was treated as a case of pneumonia and tuberculosis. Owing to the worsening condition, she had a contrast enhanced computed tomography (CECT) chest done and was diagnosed to have pulmonary embolism. She underwent pulmonary embolectomy. The histopathological examination of the embolus revealed it to be metastatic choriocarcinoma. She showed a good response to chemotherapy. Metastatic choriocarcinoma should be considered as a differential diagnosis in females presenting with pulmonary embolism.
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- 2015
13. Successful surgical management of a rare esophageal inflammatory myofibroblastic tumour: a case report
- Author
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Prakash Sayami, Uttam Krishna Shrestha, Ranjan Sapkota, and Prabhat Khakural
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Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Esophageal Neoplasms ,Enucleation ,Case Report ,Granuloma, Plasma Cell ,Submucosal esophageal tumor ,medicine ,Humans ,Esophagus ,business.industry ,Inflammatory myofibroblastic tumour ,General Medicine ,Dysphagia ,Middle Aged ,medicine.disease ,Surgery ,Cardiac surgery ,medicine.anatomical_structure ,Treatment Outcome ,Cardiothoracic surgery ,Granuloma ,Female ,medicine.symptom ,Submucosal mass ,business ,Cardiology and Cardiovascular Medicine ,Deglutition Disorders - Abstract
Inflammatory myofibroblastic tumour (IMT) is an uncommon mesenchymal tumour, which can occur anywhere in the body, rarely in esophagus. Mostly, the diagnosis is postoperative, after the hispathological evaluation of the specimen. There are no definite guidelines regarding the diagnosis and management. Here, we report a 60 year old lady presenting with dysphagia, diagnosed to have a submucosal esophageal tumor with Barium esophagogram and contrast enhanced computed tomography. She was managed successfully with surgical enucleation with the final histopathological diagnosis of IMT. Surgical excision is not only therapeutic but also diagnostic in such cases.
- Published
- 2015
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