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Stunting is a condition in which children under five years old fail to thrive due to chronic malnutrition in the first 1000 days of life and the height is below the height chart (<-2 SD) on standard age. Although stunting has negative great impact on the child growth and development, parents frequently are not concert about it due to lack of information regarding stunting. The COVID-19 pandemic also contributes on fulfillment of nutritious food, nonroutine checks for the child growth and development at the posyandu, and even stopped posyandu activities. Therefore, it is still challenging to detect the incidence of stunting in the community. This program aims to increase the knowledge and raise awareness of the importance of the first 1000 days if life in a child's growth and development also to increase the cadre skill in the early detection of stunting. The community service activity was held in the area of the Morokrembangan Primary Health Center include health promotion and training for early detection of stunting through anthropometric examination for posyandu cadre, pregnancy mother and mother of under 5 years old child. Evaluation was done by measuring the increasing of participants knowledge about stunting through pretest and posttest. There was a significant difference (p = 0.000) between the pretest and posttest. It means that this program activities have succeeded in increasing the knowledge of mothers and cadre. A better understanding of the first 1000 days of life can improve people's behavior to prevent stunting in community. [ABSTRACT FROM AUTHOR]

Background:Childhood overweight and obesity, which are considered as global epidemic, can be assessed using Body Mass Index (BMI). BMI difference can lead to anatomic changes due to an increased body load. This increase might also affect motor performance, including changes in postural balance and muscle strength. Aims and Objectives: to explain the influence of BMI on postural balance and lower limb muscle strength and to assess the correlation between those two variables in children aged 8-10 years. Material and methods:The sample consisted of 63 children aged 8-10 years, which were divided in 3 groups: BMI-normal, BMI-overweight, and BMI-obese. The postural balance was assessed using single leg balance test on MatScan and the Center Of Pressure (COP) area was recorded. Isometric muscle strength of hip extensor and knee extensor were measured using a hand-held dynamometer. Results: Obese children had significantly largerCOP area than overweight (p = 0.004) and normal weight children (p = 0.000).There were no significant differences in hip extensor muscle strength between obese children with overweight and normal weight children (p=0.527). The absolute knee extensor muscle strength in obese group was significantly higher than the over-weight and normal group (p = 0.003). However the relative muscle strength of lower limb for obese children was significantly lower than for normal weight. There was no significant correlation between absolute hip extensor and knee extensor muscles strength with COP area. Conclusion: Obese children have decreased postural balance and increased absolute knee extensor muscle strength significantly when compared to overweight and normal children. There is no significant correlation between postural balance and muscle strength. [ABSTRACT FROM AUTHOR]

Introduction: Methotrexate (MTX), Moringa oleifera (MO), and Andrographis paniculata (AP) have been reported to have anti-hyperglycemic, antioxidative, and anti-inflammatory effects in diabetic rats. This study aims to investigate the single and combination effects of MTX, MO, and AP on random blood glucose levels, interleukin-6 (IL-6) levels, and trabecular density in diabetic rats. Methods: A total of 49 male rats were divided into seven groups, namely one control group and six diabetes mellitus (DM) groups. All rats in the DM groups were injected with streptozotocin-nicotinamide (STZ-NA) intraperitoneally. In addition, the DM groups were administered with a placebo daily (DG), a single dose of 500 mg/kg BW MO daily (DG+MO), a single dose of 500mg/kg BW AP daily (DG+AP), a single dose of 7 mg/kg BW MTX once a week (DG+MTX), a combination of MTX+MO, and a combination MTX+AP, respectively. The experiment lasted for 28 days. On day 29, the right and left femur of the rats were collected for IL-6 examination (ELISA) and histopathological analysis. Results: IL-6 expression levels were significantly lower in diabetic rats treated with single and combination of MTX, MO, and AP compared to untreated diabetic rats (p < 0.05). However, the random blood glucose levels and trabecular density between treated and untreated diabetic rats were not significantly different (p < 0.001, p = 0.152). In addition, IL-6 levels were not correlated with trabecular density in all groups (r = -0.057, p = 0.722). Conclusion: Single doses of MTX, MO leaf extract, and AP leaf extract could suppress IL-6 expression in the femur tissue in diabetic rats. However, the IL-6 expression was not correlated with trabecular density although it significantly affected blood glucose levels in this study. [ABSTRACT FROM AUTHOR]