1. The Effect of the Ionizing Radiation on Hydroxyapatite-Polydimethylsiloxane Layers
- Author
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Groza, Andreea, Iconaru, Simona Liliana, Jiga, Gabriel, Chapon, Patrick, Gaiaschi, Sofia, Verga, Nicolae, Beuran, Mircea, Prodan, Alina Mihaela, Matei, Mihai, Marinescu, Serban Andrei, Trusca, Roxana, and Predoi, Daniela
- Subjects
Hydroxyapatites ,Ionizing radiation ,Dimethylpolysiloxane -- Usage ,Dental implants ,Infrared spectroscopy ,Titanium ,Microscopy ,Antibacterial agents ,Radiation (Physics) ,Spectroscopy ,Electron microscopy ,Engineering and manufacturing industries ,Science and technology - Abstract
The bio hydroxyapatite (HAp) was used from a long time in different medical and environmental applications. The HAp layers with a uniform surface were used for various medical applications such as orthopedic and dental metal implants. In this work, we reported on the influence of X-ray radiation on the structural and morphological properties of composite layers based on HAp and polydimethylsiloxane (PDMS) deposited on titanium substrates. The HAp:PDMS layers were investigated by different complementary methods such as scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), and glow discharge optical emission spectrometry (GDOES). FTIR spectral analysis showed that the molecular structure of the coatings was not changed after their irradiation even though, the depth profile analysis performed by GDOES indicated a depletion of Ca and P elements from the HAp:PDMS irradiated samples. By SEM, we showed that the morphological features of the coatings were also changed, as the irradiated layers are delaminated. The biological assays confirmed that the antibacterial activity of HAp:PDMS composite layers increased after irradiation. The results obtained in this study highlighted that the biological properties of HAp:PDMS layers could be influenced by irradiation., INTRODUCTION In the last years, hydroxyapatite (HAp) powders have been widely used in the medical field as bioactive coatings for implants, due to their outstanding properties such as good biocompatibility, [...]
- Published
- 2019
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