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27 results on '"Prosperi, Margherita"'

1. A Randomized Controlled Trial into the Effects of Probiotics on Electroencephalography in Preschoolers with Autism

Author

Billeci, Lucia, Callara, Alejandro Luis, Guiducci, Letizia, Prosperi, Margherita, Morales, Maria Aurora, Calderoni, Sara, Muratori, Filippo, and Santocchi, Elisa

Abstract

Previous studies suggest that autism spectrum disorders are characterized by alterations in the microbiota-gut-brain axis. Probiotics may modify the composition and the functionality of the gut microbiota of autism spectrum disorder individuals, with possible cascading effects on brain function. In this study, we analyzed possible brain modifications induced by the administration of probiotics in 46 children with autism spectrum disorder using electroencephalography. A randomized 6-month controlled trial was performed. In subjects treated with probiotics, we observed a decrease of power in frontopolar regions in beta and gamma bands, and increased coherence in the same bands together with a shift in frontal asymmetry, which suggests a modification toward a typical brain activity. Electroencephalography measures were significantly correlated with clinical and biochemical measures. These findings support the importance of further investigations on probiotics' benefits in autism spectrum disorder to better elucidate mechanistic links between probiotics supplementation and changes in brain activity.

Published
2023
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2. A Combined Study on the Use of the Child Behavior Checklist 1½-5 for Identifying Autism Spectrum Disorders at 18 Months

Author

Chericoni, Natasha, Balboni, Giulia, Costanzo, Valeria, Mancini, Alice, Prosperi, Margherita, Lasala, Roberta, Tancredi, Raffaella, Scattoni, Maria Luisa, Molteni, Massimo, Valeri, Giovanni, Vicari, Stefano, Zoccante, Leonardo, Arduino, Maurizio, Venuti, Paola, Sogos, Carla, Guzzetta, Andrea, Muratori, Filippo, and Apicella, Fabio

Abstract

The capacity of the Child Behavior Checklist 1½-5 (CBCL 1½-5) to identify children with autism spectrum disorder (ASD) at 18 months was tested on 37 children clinically referred for ASD and 46 children at elevated likelihood of developing ASD due to having an affected brother/sister. At 30 months the clinically referred children all received a confirmatory diagnosis, and 10 out of 46 siblings received a diagnosis of ASD. CBCL 1½-5 profiles were compared with a group of matched children with typical development (effect of cognitive level controlled for). The capacity of the CBCL 1½-5 DSM Oriented-Pervasive Developmental Problems scale to differentiate correctly between children diagnosed with ASD and children with typical development appeared dependent on group ascertainment methodology.

Published
2021
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3. Expression of miRNAs in Pre-Schoolers with Autism Spectrum Disorders Compared with Typically Developing Peers and Its Effects after Probiotic Supplementation

Author

Guiducci, Letizia, primary, Cabiati, Manuela, additional, Santocchi, Elisa, additional, Prosperi, Margherita, additional, Morales, Maria Aurora, additional, Muratori, Filippo, additional, Randazzo, Emioli, additional, Federico, Giovanni, additional, Calderoni, Sara, additional, and Del Ry, Silvia, additional

Published
2023
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4. Behavioral Phenotype of ASD Preschoolers with Gastrointestinal Symptoms or Food Selectivity

Author

Prosperi, Margherita, Santocchi, Elisa, Balboni, Giulia, Narzisi, Antonio, Bozza, Margherita, Fulceri, Francesca, Apicella, Fabio, Igliozzi, Roberta, Cosenza, Angela, Tancredi, Raffaella, Calderoni, Sara, and Muratori, Filippo

Abstract

This study investigated the prevalence and type of gastrointestinal (GI) and food selectivity (FS) symptoms in 163 preschoolers with ASD, and their possible links with core ASD features and emotional/behavioural problems. 40.5% of children with ASD had at least one severe GI symptom or FS. Preschoolers with and without GI symptoms and with and without FS were significantly different on several emotional/behavioural problems and restrictive/repetitive behaviours, whereas they did not differ significantly on performance IQ and autistic severity. The GI plus FS group presented with Sleep Problems, Self-injurious Behaviors and Anxiety Problems. Results indicated the need for early identification of GI disturbances and FS in order to design tailored intervention for these symptoms frequently associated to challenging behaviours in ASD.

Published
2017
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5. ARIANNA: A research environment for neuroimaging studies in autism spectrum disorders

Author

Retico, Alessandra, Arezzini, Silvia, Bosco, Paolo, Calderoni, Sara, Ciampa, Alberto, Coscetti, Simone, Cuomo, Stefano, De Santis, Luca, Fabiani, Dario, Fantacci, Maria Evelina, Giuliano, Alessia, Mazzoni, Enrico, Mercatali, Pietro, Miscali, Giovanni, Pardini, Massimiliano, Prosperi, Margherita, Romano, Francesco, Tamburini, Elena, Tosetti, Michela, and Muratori, Filippo

Published
2017
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10. sj-docx-1-aut-10.1177_13623613221082710 – Supplemental material for A randomized controlled trial into the effects of probiotics on electroencephalography in preschoolers with autism

Author

Billeci, Lucia, Callara, Alejandro Luis, Guiducci, Letizia, Prosperi, Margherita, Morales, Maria Aurora, Calderoni, Sara, Muratori, Filippo, and Santocchi, Elisa

Subjects
FOS: Psychology, FOS: Clinical medicine, 170199 Psychology not elsewhere classified, 111799 Public Health and Health Services not elsewhere classified, FOS: Educational sciences, 110319 Psychiatry (incl. Psychotherapy), FOS: Health sciences, 130312 Special Education and Disability, Education
Abstract

Supplemental material, sj-docx-1-aut-10.1177_13623613221082710 for A randomized controlled trial into the effects of probiotics on electroencephalography in preschoolers with autism by Lucia Billeci, Alejandro Luis Callara, Letizia Guiducci, Margherita Prosperi, Maria Aurora Morales, Sara Calderoni, Filippo Muratori and Elisa Santocchi in Autism

Published
2022
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12. Dietary Patterns and Weight Status in Italian Preschoolers with Autism Spectrum Disorder and Typically Developing Children

Author

Raspini, Benedetta, primary, Prosperi, Margherita, additional, Guiducci, Letizia, additional, Santocchi, Elisa, additional, Tancredi, Raffaella, additional, Calderoni, Sara, additional, Morales, Maria Aurora, additional, Morelli, Mariangela, additional, Simione, Meg, additional, Fiechtner, Lauren, additional, Muratori, Filippo, additional, and Cena, Hellas, additional

Published
2021
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15. Sex Differences in Autism Spectrum Disorder: An Investigation on Core Symptoms and Psychiatric Comorbidity in Preschoolers

Author

Prosperi, Margherita, primary, Turi, Marco, additional, Guerrera, Silvia, additional, Napoli, Eleonora, additional, Tancredi, Raffaella, additional, Igliozzi, Roberta, additional, Apicella, Fabio, additional, Valeri, Giovanni, additional, Lattarulo, Caterina, additional, Gemma, Andrea, additional, Santocchi, Elisa, additional, Calderoni, Sara, additional, Muratori, Filippo, additional, and Vicari, Stefano, additional

Published
2021
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17. Effects of Probiotic Supplementation on Gastrointestinal, Sensory and Core Symptoms in Autism Spectrum Disorders: A Randomized Controlled Trial

Author

Santocchi, Elisa, primary, Guiducci, Letizia, additional, Prosperi, Margherita, additional, Calderoni, Sara, additional, Gaggini, Melania, additional, Apicella, Fabio, additional, Tancredi, Raffaella, additional, Billeci, Lucia, additional, Mastromarino, Paola, additional, Grossi, Enzo, additional, Gastaldelli, Amalia, additional, Morales, Maria Aurora, additional, and Muratori, Filippo, additional

Published
2020
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18. Vocal and motor behaviors as a possible expression of gastrointestinal problems in preschoolers with Autism Spectrum Disorder

Author

Prosperi Margherita and Guiducci Letizia

Abstract

This record contains raw data related to article "Vocal and motor behaviors as a possible expression of gastrointestinal problems in preschoolers with Autism Spectrum Disorder" funded by the Italian Ministry of Health and by Tuscany Region with the grant ‘GR-2011-02348280’. This work was also partially supported by grant from the IRCCS Stella Maris Foundation (Ricerca Corrente, and the “5 × 1000” voluntary contributions, Italian Ministry of Health).

Published
2019
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21. Parental Perspectives on Psychiatric Comorbidity in Preschoolers With Autism Spectrum Disorders Receiving Publicly Funded Mental Health Services

Author

Muratori, Filippo, primary, Turi, Marco, additional, Prosperi, Margherita, additional, Narzisi, Antonio, additional, Valeri, Giovanni, additional, Guerrera, Silvia, additional, Santocchi, Elisa, additional, Apicella, Fabio, additional, Lattarulo, Caterina, additional, Calderoni, Sara, additional, and Vicari, Stefano, additional

Published
2019
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22. ARIANNA: un Ambiente di Ricerca Interdisciplinare per l’Analisi di Neuroimmagini Nell’Autismo

Author

Silvia, Arezzini, Paolo, Bosco, Calderoni, Sara, Alberto, Ciampa, Coscetti, Simone, Stefano, Cuomo, LUCA DE SANTIS, Dario, Fabiani, Fantacci, MARIA EVELINA, Gerardo, Giardiello, Giuliano, Alessia, Enrico, Mazzoni, Mercatali, Pietro, Giovanni, Miscali, Muratori, Filippo, Massimiliano, Pardini, Prosperi, Margherita, Alessandra, Retico, Francesco, Romano, Elena, Tamburini, and Tosetti, Michela

Published
2016

23. Serological screening for Celiac Disease in 382 pre-schoolers with Autism Spectrum Disorder

Author

Calderoni, Sara, primary, Santocchi, Elisa, additional, Del Bianco, Teresa, additional, Brunori, Elena, additional, Caponi, Laura, additional, Paolicchi, Aldo, additional, Fulceri, Francesca, additional, Prosperi, Margherita, additional, Narzisi, Antonio, additional, Cosenza, Angela, additional, Tancredi, Raffaella, additional, and Muratori, Filippo, additional

Published
2016
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24. Sex Differences in Autism Spectrum Disorder: An Investigation on Core Symptoms and Psychiatric Comorbidity in Preschoolers

Author

Margherita Prosperi, Marco Turi, Silvia Guerrera, Eleonora Napoli, Raffaella Tancredi, Roberta Igliozzi, Fabio Apicella, Giovanni Valeri, Caterina Lattarulo, Andrea Gemma, Elisa Santocchi, Sara Calderoni, Filippo Muratori, Stefano Vicari, Prosperi, Margherita, Turi, Marco, Guerrera, Silvia, Napoli, Eleonora, Tancredi, Raffaella, Igliozzi, Roberta, Apicella, Fabio, Valeri, Giovanni, Lattarulo, Caterina, Gemma, Andrea, Santocchi, Elisa, Calderoni, Sara, Muratori, Filippo, and Vicari, Stefano

Subjects
sex differences, Cognitive Neuroscience, autism, CBCL, behavioral disciplines and activities, lcsh:RC346-429, lcsh:RC321-571, Autism Diagnostic Observation Schedule, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, psychiatric comorbidities, mental disorders, medicine, preschoolers, psychiatric comorbiditie, 0501 psychology and cognitive sciences, child behavior checklist, 10. No inequality, Child Behavior Checklist, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, lcsh:Neurology. Diseases of the nervous system, Original Research, Intelligence quotient, business.industry, 05 social sciences, preschooler, medicine.disease, Sensory Systems, autistic female, Autism spectrum disorder, Anxiety, Autism, autistic females, medicine.symptom, business, 030217 neurology & neurosurgery, Neuroscience, 050104 developmental & child psychology, Psychopathology, Clinical psychology
Abstract

Findings regarding sex differences in autism spectrum disorder (ASD), as far as core symptoms and psychiatric comorbidities (PC) are concerned, are inconsistent, inconclusive, or conflicting among studies. The lower prevalence of ASD in females than in males and the age and intelligence quotient (IQ) heterogeneity among samples made it difficult to investigate these differences. This case–control study tries to deepen the impact of sex differences on core symptoms of autism and PC in 214 preschoolers with ASD (mean age, 45.26) without impairment in non-verbal IQ (nvIQ ≥70). A total of 107 ASD females (mean age, 44.51 ± 13.79 months) were matched one by one with 107 males (mean age, 46.01 ± 13.42 months) for chronological age (±6 months) and nvIQ (±6 points). We used the Autism Diagnostic Observation Schedule 2 (ADOS-2) and the Child Behavior Checklist (CBCL) 1.5–5 to explore autism severity and PC. The results highlight that ASD females did not significantly differ from ASD males regarding the severity of autism. Statistically significant lower levels of emotionally reactive (p = 0.005, η2 = 0.04), anxious-depressed (p = 0.001, η2 = 0.05), internalizing problems (p = 0.04, η2 = 0.02), and DSM-Oriented Scales anxiety problems (p = 0.02, η2 = 0.04) in ASD females than in ASD males were also detected. Our findings of no difference in the autism severity and lower internalizing problems in females than males with ASD extend the knowledge of autism in females during preschool years. Compared to other similar studies on this topic, we can state that these results are not supported by differences in nvIQ between sexes nor by the presence of cognitive impairment. It confirms the need for clinicians to consider sex differences when describing autism psychopathology.

Published
2021
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25. Parental perspectives on psychiatric comorbidity in preschoolers with autism spectrum disorders receiving publicly funded mental health services

Author

Filippo Muratori, Marco Turi, Margherita Prosperi, Antonio Narzisi, Giovanni Valeri, Silvia Guerrera, Elisa Santocchi, Fabio Apicella, Caterina Lattarulo, Sara Calderoni, Stefano Vicari, Muratori, Filippo, Turi, Marco, Prosperi, Margherita, Narzisi, Antonio, Valeri, Giovanni, Guerrera, Silvia, Santocchi, Elisa, Apicella, Fabio, Lattarulo, Caterina, Calderoni, Sara, and Vicari, Stefano

Subjects
ADHD problems, Affective problems, Anxiety problems, Child behavior checklist 1.5-5, Multicomorbidity, Oppositional problems, Sleep problems, Young children, lcsh:RC435-571, Anxiety problem, CBCL, affective problems, anxiety problems, child behavior checklist 1.5–5, multicomorbidity, oppositional problems, sleep problems, young children, Affect (psychology), behavioral disciplines and activities, Sleep problem, 03 medical and health sciences, 0302 clinical medicine, Settore MED/39 - NEUROPSICHIATRIA INFANTILE, ADHD problem, lcsh:Psychiatry, mental disorders, Medicine, Oppositional problem, Child Behavior Checklist, Original Research, Psychiatry, business.industry, medicine.disease, Mental health, Comorbidity, 030227 psychiatry, Psychiatry and Mental health, Anxiety, Autism, Affective problem, Analysis of variance, medicine.symptom, business, 030217 neurology & neurosurgery, Clinical psychology
Abstract

An increased prevalence of psychiatric comorbidity (PC) in individuals with Autism Spectrum Disorders (ASD) is consistently reported. While several studies have examined PC in school-aged children, adolescents and adults with ASD, investigations on PC in preschoolers are less common. In this study, we explore the prevalence and the type of PC in a sample of 989 preschoolers with ASD through the DSM-Oriented Scales (DOS) of the Child Behavior Checklist (CBCL 1½-5) and their possible links with the core features of ASD and cognitive functioning. Results indicated that 37.8% of the sample had at least one PC in addition to ASD; these subjects displayed significantly higher Total score (p = 0.02) and Social Affect score (p = 0.003) on the ADOS-based calibrated severity scores (CSS), as well as lower (p ≤ 0.0001) performance IQ (pIQ) compared to ASD individuals without PC. As far as the specific DOS, Affective Problems (AP) were detected in 23.4% of the whole sample, ADHD Problems (ADHD) in 17.3%, Anxiety Problems (AXP) in 16.7%, and Oppositional Problems (OP) in 7.9%. These different comorbidities were isolated in 195 subjects (Mono-comorbid group: 19.7% of the whole sample), while 179 subjects (18.1% of the whole sample) had two or more types of PC (Multi-comorbid group). One-way ANOVA revealed that subjects with multi-comorbidity have statistically significant lower pIQ and higher Total score and Social Affect score on CSS-ADOS. Specific differences for each type of comorbidity and gender differences were also discussed. Taken together, results indicate a considerable presence of PC in preschoolers with ASD that should be accurately considered during the assessment and diagnosis process in order to plan a tailored intervention based not only on core symptoms of ASD, but also on comorbid psychiatric condition since preschool age.

Published
2019

26. [Archives for the history of malaria].

Author

Prosperi MB

Subjects
History, 19th Century, History, 20th Century, Humans, Rome, Universities, Archives history, Malaria history
Abstract

Archives for the history of malaria and malariology in Italy have been 'rediscovered' in the recent past. The Sezione di Storia della Medicina at Rome University conserves many different personal and institutional archives closely or loosely related to this topic. Many of them had been originally gathered and kept at the Istituto di Igiene at Rome University. Among them the Fondo Casini, of the 20th century, documenting the activity of public institutions such as the Società per gli Studi della Malaria and the Scuola Superiore di Malariologia; archives of the end of the 19th and beginning of the 20th century, such as the Fondo Bignami, Celli; and many others.

Published
2006

27. [The Buzzati Traverso archive].

Author

Prosperi MB and Lisi C

Subjects
Biomedical Research history, History, 20th Century, Italy, Public Policy, Archives, Genetics history, Science history
Abstract

The life and activity of Adriano Buzzati-Traverso are significantly linked to the birth and development of genetics in Italy, as well as to the achievements and the shortcomings of the creation of a 'modern' notion and policy of science in our country. His archive sheds light on public and private aspects of his activity, especially the creation of important research centers.

Published
2006

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