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838 results on '"Przybilla, Bernhard"'

2. Correction to: Guideline for the diagnosis of drug hypersensitivity reactions

Author

Brockow, Knut, Przybilla, Bernhard, Aberer, Werner, Bircher, Andreas J., Brehler, Randolf, Dickel, Heinrich, Fuchs, Thomas, Jakob, Thilo, Lange, Lars, Pfützner, Wolfgang, Mockenhaupt, Maja, Ott, Hagen, Pfaar, Oliver, Ring, Johannes, Sachs, Bernhardt, Sitter, Helmut, Trautmann, Axel, Treudler, Regina, Wedi, Bettina, Worm, Margitta, Wurpts, Gerda, Zuberbier, Torsten, and Merk, Hans F.

Published
2017
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4. S2k guideline on diagnosis and treatment of atopic dermatitis — short version

Author

Werfel, Thomas, Heratizadeh, Annice, Aberer, Werner, Ahrens, Frank, Augustin, Matthias, Biedermann, Tilo, Diepgen, Thomas, Fölster-Holst, Regina, Gieler, Uwe, Kahle, Julia, Kapp, Alexander, Nast, Alexander, Nemat, Katja, Ott, Hagen, Przybilla, Bernhard, Roecken, Martin, Schlaeger, Martin, Schmid-Grendelmeier, Peter, Schmitt, Jochen, Schwennesen, Thomas, Staab, Doris, and Worm, Margitta

Published
2016
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5. Fortschritte in der Allergiediagnostik

Author

Przybilla, Bernhard, Aberer, Werner, Darsow, Ulf G., Eberlein-König, Bernadette, Kleine-Tebbe, Jörg, Merk, Hans F., Saloga, Joachim, Plewig, Gerd, editor, Kaudewitz, Peter, editor, and Sander, Christian A., editor

Published
2005
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12. Guideline for the diagnosis of drug hypersensitivity reactions: S2K-Guideline of the German Society for Allergology and Clinical Immunology (DGAKI) and the German Dermatological Society (DDG) in collaboration with the Association of German Allergologists (AeDA), the German Society for Pediatric Allergology and Environmental Medicine (GPA), the German Contact Dermatitis Research Group (DKG), the Swiss Society for Allergy and Immunology (SGAI), the Austrian Society for Allergology and Immunology (ÖGAI), the German Academy of Allergology and Environmental Medicine (DAAU), the German Center for Documentation of Severe Skin Reactions and the German Federal Institute for Drugs and Medical Products (BfArM)

Author

Brockow, Knut, Przybilla, Bernhard, Aberer, Werner, Bircher, Andreas J., Brehler, Randolf, Dickel, Heinrich, Fuchs, Thomas, Jakob, Thilo, Lange, Lars, Pfützner, Wolfgang, Mockenhaupt, Maja, Ott, Hagen, Pfaar, Oliver, Ring, Johannes, Sachs, Bernhardt, Sitter, Helmut, Trautmann, Axel, Treudler, Regina, Wedi, Bettina, Worm, Margitta, Wurpts, Gerda, Zuberbier, Torsten, and Merk, Hans F.

Published
2015
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13. Hyposensibilisierung

Author

Przybilla, Bernhard, Ruëff, Franziska, Thomas, Peter, Plewig, Gerd, editor, and Korting, Hans Christian, editor

Published
1995
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14. Guideline contact dermatitis: S1-Guidelines of the German Contact Allergy Group (DKG) of the German Dermatology Society (DDG), the Information Network of Dermatological Clinics (IVDK), the German Society for Allergology and Clinical Immunology (DGAKI), the Working Group for Occupational and Environmental Dermatology (ABD) of the DDG, the Medical Association of German Allergologists (AeDA), the Professional Association of German Dermatologists (BVDD) and the DDG

Author

Brasch, Jochen, Becker, Detlef, Aberer, Werner, Bircher, Andreas, Kränke, Birger, Jung, Kirsten, Przybilla, Bernhard, Biedermann, Tilo, Werfel, Thomas, John, Swen Malte, Elsner, Peter, Diepgen, Thomas, Trautmann, Axel, Merk, Hans F., Fuchs, Thomas, and Schnuch, Axel

Published
2014
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15. Guideline for acute therapy and management of anaphylaxis: S2 Guideline of the German Society for Allergology and Clinical Immunology (DGAKI), the Association of German Allergologists (AeDA), the Society of Pediatric Allergy and Environmental Medicine (GPA), the German Academy of Allergology and Environmental Medicine (DAAU), the German Professional Association of Pediatricians (BVKJ), the Austrian Society for Allergology and Immunology (ÖGAI), the Swiss Society for Allergy and Immunology (SGAI), the German Society of Anaesthesiology and Intensive Care Medicine (DGAI), the German Society of Pharmacology (DGP), the German Society for Psychosomatic Medicine (DGPM), the German Working Group of Anaphylaxis Training and Education (AGATE) and the patient organization German Allergy and Asthma Association (DAAB)

Author

Ring, Johannes, Beyer, Kirsten, Biedermann, Tilo, Bircher, Andreas, Duda, Dorothea, Fischer, Jörg, Friedrichs, Frank, Fuchs, Thomas, Gieler, Uwe, Jakob, Thilo, Klimek, Ludger, Lange, Lars, Merk, Hans F., Niggemann, Bodo, Pfaar, Oliver, Przybilla, Bernhard, Ruëff, Franziska, Rietschel, Ernst, Schnadt, Sabine, Seifert, Roland, Sitter, Helmut, Varga, Eva-Maria, Worm, Margitta, and Brockow, Knut

Published
2014
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18. Predictors of side effects during the buildup phase of venom immunotherapy for Hymenoptera venom allergy: The importance of baseline serum tryptase †

Author

Ruëff, Franziska, Przybilla, Bernhard, Biló, Maria Beatrice, Müller, Ulrich, Scheipl, Fabian, Aberer, Werner, Birnbaum, Joëlle, Bodzenta-Lukaszyk, Anna, Bonifazi, Floriano, Bucher, Christoph, Campi, Paolo, Darsow, Ulf, Egger, Cornelia, Haeberli, Gabrielle, Hawranek, Thomas, Kucharewicz, Iwona, Küchenhoff, Helmut, Lang, Roland, Quercia, Oliviero, Reider, Norbert, Severino, Maurizio, Sticherling, Michael, Sturm, Gunter Johannes, and Wüthrich, Brunello

Published
2010
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20. S2k-Leitlinie Neurodermitis [atopisches Ekzem; atopische Dermatitis] – Kurzversion

Author

Werfel, Thomas, Heratizadeh, Annice, Aberer, Werner, Ahrens, Frank, Augustin, Matthias, Biedermann, Tilo, Diepgen, Thomas, Fölster-Holst, Regina, Gieler, Uwe, Kahle, Julia, Kapp, Alexander, Nast, Alexander, Nemat, Katja, Ott, Hagen, Przybilla, Bernhard, Roecken, Martin, Schlaeger, Martin, Schmid-Grendelmeier, Peter, Schmitt, Jochen, Schwennesen, Thomas, Staab, Doris, and Worm, Margitta

Published
2016
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21. Predictors of severe systemic anaphylactic reactions in patients with Hymenoptera venom allergy: Importance of baseline serum tryptase—a study of the European Academy of Allergology and Clinical Immunology Interest Group on Insect Venom Hypersensitivity

Author

Ruëff, Franziska, Przybilla, Bernhard, Biló, Maria Beatrice, Müller, Ulrich, Scheipl, Fabian, Aberer, Werner, Birnbaum, Joëlle, Bodzenta-Lukaszyk, Anna, Bonifazi, Floriano, Bucher, Christoph, Campi, Paolo, Darsow, Ulf, Egger, Cornelia, Haeberli, Gabrielle, Hawranek, Thomas, Körner, Michael, Kucharewicz, Iwona, Küchenhoff, Helmut, Lang, Roland, Quercia, Oliviero, Reider, Norbert, Severino, Maurizio, Sticherling, Michael, Sturm, Gunter Johannes, and Wüthrich, Brunello

Published
2009
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31. Nahrungsmittelallergie

Author

Rerinck, Helen-Caroline, primary, Aberer, Werner, additional, Ballmer-Weber, Barbara K., additional, Ruëff, Franziska, additional, Schäfer, Torsten, additional, Worm, Margitta, additional, and Przybilla, Bernhard, additional

Published
2009
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44. Neurodermitis S2-Leitlinie

Author

Werfel, Thomas, Aberer, Werner, Augustin, Matthias, Biedermann, Tilo, Fölster-Holst, Regina, Friedrichs, Frank, Gieler, Uwe, Heratizadeh, Annice, Kapp, Alexander, Przybilla, Bernhard, Rietschel, Ernst, Schlaeger, Martin, Schmid-Grendelmeier, Peter, Sitters, Helmut, Staab, Doris, Szczepanski, Rüdiger, Vieluf, Dieter, Voigtmann, Ingrid, and Worm, Margitta

Published
2009
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47. Atopy patch testing with aeroallergens in a large clinical population of dermatitis patients in Germany and Switzerland, 2000-2015

Author

Dickel, Heinrich (Prof. Dr. med.), Kuhlmann, Lea (Dr. med.), Bauer, Andrea (Prof. Dr. med. habil.), Bircher, Andreas J. (Prof. Dr.), Breuer, Kristine (PD Dr. med.), Fuchs, Thomas (Prof. Dr. med.), Grabbe, Jürgen (Prof. Dr. med.), Mahler, Vera (Prof. Dr. med.), Pföhler, Claudia (Prof. Dr. med.), Przybilla, Bernhard (Prof. Dr. med.), Rieker-Schwienbacher, Juliane, Schröder-Kraft, Claudia (Dr. med.), Simon, Dagmar (Prof. Dr. med.), Treudler, Regina (Prof. Dr. med.), Weisshaar, Elke (apl. Prof. Dr. med.), Worm, Margitta (Prof. Dr. med.), Trinder, Elke, and Geier, Johannes (Prof. Dr. med.)

Subjects
ddc:610
Abstract

\(\ bf Background\) The diagnostic significance of the atopy patch test for the management of dermatitis possibly triggered by aeroallergens is still controversial. However, sufficiently large studies with routinely tested standardized aeroallergen patch test preparations in dermatitis patients are lacking. \(\ bf Objective\) To evaluate the reaction frequency and the reaction profiles of 10 until mid-2015 commercially available, standardized aeroallergen patch test preparations of the ‘Stallerpatch’ test series (Stallergenes, Antony Cedex, France) in a large multicentre patient cohort. \(\ bf Methods\) A retrospective data analysis of patients with suspected aeroallergen-dependent eczematous skin lesions was performed, who were patch tested in 15 Information Network of Departments of Dermatology-associated clinics between 2000 and 2015. Patients were stratified according to their atopic dermatitis (AD) status. \(\ bf Results\) The study group included 3676 patients (median age 41 years, 34.8% males, 54.5% AD). The most common aeroallergens causing positive patch test reactions were Dermatophagoides pteronyssinus (19.6%), Dermatophagoides farinae (16.9%), birch (6.2%), timothy grass (6.0%), cat dander (5.4%), mugwort (4.9%) and dog dander (4.6%). Reactions to other pollen allergen preparations, that is 5 grasses (3.2%), cocksfoot (2.1%) and plantain (1.6%), were less common. Positive patch test reactions to aeroallergens were consistently more frequent in patients with AD. These patients showed proportionally less dubious, follicular, irritant and weak positive reactions. Independent of AD status, a patient history of past or present allergic rhinitis was associated with an increased chance of a positive aeroallergen patch test reaction to pollen allergens. \(\ bf Conclusion\) The aeroallergen patch test is a useful add-on tool in clinical routine, especially in patients with AD and/or respiratory allergy. A patch test series comprising Dermatophagoides pteronyssinus, Dermatophagoides farinae, birch, timothy grass, cat dander and mugwort seems to be suitable. Controlled studies with specific provocation and elimination procedures are required to further evaluate the diagnostic significance of the proposed screening series.

Published
2020

48. Allergologische Diagnostik von Überempfindlichkeitsreaktionen auf Arzneimittel

Author

Przybilla, Bernhard, Aberer, Werner, Bircher, Andreas J., Brehler, Randolph, Brockow, Knut, Dickel, Heinrich, Fuchs, Thomas, Hertl, Michael, Mockenhaupt, Maja, Pfaar, Oliver, Ring, Johannes, Sachs, Bernhardt, Vieluf, Dieter, Wedi, Bettina, Worm, Margitta, Zuberbier, Torsten, and Merk, Hans F.

Published
2008

49. Allergological approach to drug hypersensitivity reactions

Author

Przybilla, Bernhard, Aberer, Werner, Bircher, Andreas J., Brehler, Randolph, Brockow, Knut, Dickel, Heinrich, Fuchs, Thomas, Hertl, Michael, Mockenhaupt, Maja, Pfaar, Oliver, Ring, Johannes, Sachs, Bernhardt, Vieluf, Dieter, Wedi, Bettina, Worm, Margitta, Zuberbier, Torsten, and Merk, Hans F.

Published
2008

50. Comparative analysis of the phototoxicity induced by BRAF inhibitors and alleviation through antioxidants

Author

Heppt, Markus V, Clanner-Engelshofen, Benjamin M, Marsela, Enklajd, Wessely, Anja, Kammerbauer, Claudia, Przybilla, Bernhard, French, Lars E, Berking, Carola, and Reinholz, Markus

Subjects
phototoxicity, antioxidant, protein kinase inhibitor, targeted therapy, BRAF
Abstract

Small molecules tackling mutated BRAF (BRAFi) are an important mainstay of targeted therapy in a variety of cancers including melanoma. Albeit commonly reported as side effect, the phototoxic potential of many BRAFi is poorly characterized. In this study, we evaluated the phototoxicity of 17 distinct agents and investigated whether BRAFi-induced phototoxicity can be alleviated by antioxidants. The ultraviolet (UV) light absorbance of 17 BRAFi was determined. Their phototoxic potential was investigated independently with a reactive oxygen species (ROS) and the 3T3 neutral red uptake (NRU) assay in vitro. To test for a possible phototoxicity alleviation by antioxidants, vitamin C, vitamin E phosphate, trolox, and glutathione (GSH) were added to the 3T3 assay of selected inhibitors. The highest cumulative absorbance for both UVA and UVB was detected for vemurafenib. The formation of ROS was more pronounced for all compounds after irradiation with UVA than with UVB. In the 3T3 NRU assay, 8 agents were classified as phototoxic, including vemurafenib, dabrafenib, and encorafenib. There was a significant correlation between the formation of singlet oxygen (p = 0.026) and superoxide anion (p

Published
2019

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