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The article presents information about comparison of the Grassi Block substitution test with the Wechsler-Bellevue in the diagnosis of organic brain damage. The present study reports the results from the use of a relatively new test for organically involved cases, the Grassi Block Substitution Test (GBST) and the Wechsler-Bellevue Intelligence Scale, as instruments for the diagnosis of organic brain damage. The findings from the use of the GBST are compared with those based upon Wechsler's signs for organicity and Wechsler's Mental Deterioration Index. The organic group was composed of 24 subjects ranging in age from 15 through 43 years of age. The educational average was eleven years of schooling. All patients were medically and clinically diagnosed as having organic brain damage and all had undergone complete neurological workups.