Search

Your search keyword '"Pu-Zhang Zi"' showing total 1 results
Start Over Author "Pu-Zhang Zi"
1 results on '"Pu-Zhang Zi"'

1. 1,6-Conjugate addition of para-quinone methides using gem-diborylcarbanions: Practical access to gem-diborylalkanes bearing vicinal tertiary/quaternary stereocenters.

Author

Pu-Zhang Zi, Xing-Bang Liu, Quan-Hong Zhao, Min He, and Yuan Huang

Subjects
*QUINONE, *ORGANOBORON compounds, *CONJUGATE addition reactions, *TEMPERATURE measurements, *CHEMICAL reactions
Abstract

A novel, efficient and pragmatic method to prepare gem-diboron products with vicinal tertiary/quaternary stereocenters using LiTMP-mediated 1,6-conjugate addition of gem-diborylalkanes to para-quinone methides was described for the first time. The results showed that various gem-diboron products with vicinal tertiary and quaternary stereocenters could be formed within 15 min at ambient temperature. This simple protocol has also been applied for the efficient synthesis of the analogue of Bedaquiline. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results