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24 results on '"Pugliese, Marta"'

1. Effectiveness of biosimilar pegfilgrastim in patients with multiple myeloma after high-dose melphalan and autologous stem cell transplantation

Author

Martino, Massimo, Gori, Mercedes, Porto, Gaetana, Pellicano, Maria, Santoro, Ludovica, Verduci, Chiara, Canale, Filippo Antonio, Loteta, Barbara, Moscato, Tiziana, Alati, Caterina, Ieracitano, Maria Consuelo, Cuzzocrea, Amelia, Altomonte, Maria, Florenzano, Maria Teresa, Morabito, Antonella, Irrera, Giuseppe, Naso, Virginia, Pugliese, Marta, Console, Giuseppe, Ferreri, Anna, Imbalzano, Lucrezia, Tripepi, Giovanni, and Pitino, Annalisa

Published
2023
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2. Correction to: Effectiveness of biosimilar pegfilgrastim in patients with multiple myeloma after high‑dose melphalan and autologous stem cell transplantation

Author

Martino, Massimo, Gori, Mercedes, Porto, Gaetana, Pellicano, Maria, Santoro, Ludovica, Verduci, Chiara, Canale, Filippo Antonio, Loteta, Barbara, Moscato, Tiziana, Alati, Caterina, Ieracitano, Maria Consuelo, Cuzzocrea, Amelia, Altomonte, Maria, Florenzano, Maria Teresa, Morabito, Antonella, Irrera, Giuseppe, Naso, Virginia, Pugliese, Marta, Console, Giuseppe, Ferreri, Anna, Imbalzano, Lucrezia, Tripepi, Giovanni, and Pitino, Annalisa

Published
2023
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4. Netupitant/palonosetron without dexamethasone for preventing nausea and vomiting in patients with multiple myeloma receiving high-dose melphalan for autologous stem cell transplantation: a single-center experience

Author

Loteta, Barbara, Paviglianiti, Annalisa, Naso, Virginia, Ferreri, Anna, Moscato, Tiziana, Console, Giuseppe, Canale, Filippo Antonio, Irrera, Giuseppe, Pugliese, Marta, Di Costanzo, Antonella, Provenzano, Pasquale Fabio, Loddo, Viviana, Porto, Gaetana, Cusumano, Giuseppa, Russo, Letteria, Meliambro, Nicola, Romeo, Valentina, Porcino, Domenico, Gallo, Salvatore, Gangemi, Tiziana, Rossetti, Antonio Maria, and Martino, Massimo

Published
2022
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5. Case Report: CAR‐T cells and subsequent maintenance with ponatinib in an adult Philadelphia acute lymphoblastic leukemia patient with hematological and extramedullary relapse after allogeneic stem cell transplantation

Author

Canale, Filippo Antonio, primary, Pitea, Martina, additional, Alati, Caterina, additional, Porto, Gaetana, additional, Pratico, Giulia, additional, Utano, Giovanna, additional, Germanò, Jessyca, additional, Imbalzano, Lucrezia, additional, Ferreri, Anna, additional, Verduci, Chiara, additional, Santoro, Ludovica, additional, Policastro, Giorgia, additional, Loteta, Barbara, additional, Pugliese, Marta, additional, and Martino, Massimo, additional

Published
2023
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6. Venetoclax durable response in adult relapsed/refractory Philadelphia-negative acute lymphoblastic leukemia with JAK/STAT pathway alterations

Author

Ferrari, Anna, primary, Cangini, Delia, additional, Ghelli Luserna di Rorà, Andrea, additional, Condorelli, Annalisa, additional, Pugliese, Marta, additional, Schininà, Giovanni, additional, Cosentino, Sebastiano, additional, Fonzi, Eugenio, additional, Domizio, Chiara, additional, Simonetti, Giorgia, additional, Leotta, Salvatore, additional, Milone, Giuseppe, additional, and Martinelli, Giovanni, additional

Published
2023
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7. Case Report: CAR‐T cells and subsequent maintenance with ponatinib in an adult Philadelphia acute lymphoblastic leukemia patient with hematological and extramedullary relapse after allogeneic stem cell transplantation.

Author

Canale, Filippo Antonio, Pitea, Martina, Alati, Caterina, Porto, Gaetana, Pratico, Giulia, Utano, Giovanna, Germanò, Jessyca, Imbalzano, Lucrezia, Ferreri, Anna, Verduci, Chiara, Santoro, Ludovica, Policastro, Giorgia, Loteta, Barbara, Pugliese, Marta, and Martino, Massimo

Subjects
EXTRAMEDULLARY diseases, STEM cell transplantation, LYMPHOBLASTIC leukemia, ACUTE leukemia, CELLULAR therapy, PLASMACYTOMA
Abstract

Relapsed or refractory (r/r) Philadelphia chromosome–positive (Ph+) acute lymphoblastic leukemia (ALL) still represent an unmet clinical need despite the new immune therapies available for these patients. We report the case of a Ph + ALL relapsed one year after allogeneic stem cell transplant. After one DLI was started CAR‐T program with brexucabtageneautoleucel, using as bridging treatment ponatinib, vincristine and prednisone. Brexu‐cel infusion was performed in 2023, without CRS or ICANS onset. One month after Brexu‐cel infusion BM aspirate and CT‐PET showed recovery of full donor chimerism, MRD negativity and complete metabolic remission. Subsequently was started maintenance with ponatinib: at last follow‐up, the patient persisted in leukemia‐free status. CAR‐T cells represent the most powerful treatment for r/r Ph + ALL but there is no consensus about the optimal bridging strategy and also regarding the management algorithm during "post CAR‐T phase". Here, we report the efficacy of ponatinib as a bridge to anti‐CD19 CAR‐T cell therapy and as post CAR‐T maintenance. Our experience suggests that a preserving approach with TKI associated to low‐dose chemotherapy can be the optimal bridging therapy prior to CAR‐T and that an "MRD‐guided" and "TKI‐based" maintenance strategy can represent the best choice for Ph + ALL which satisfactorily responds to CAR‐T. [ABSTRACT FROM AUTHOR]

Published
2024
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8. Chimeric Antigen Receptor T-Cell Therapy: What We Expect Soon

Author

Martino, Massimo, primary, Naso, Virginia, additional, Loteta, Barbara, additional, Canale, Filippo Antonio, additional, Pugliese, Marta, additional, Alati, Caterina, additional, Musuraca, Gerardo, additional, Nappi, Davide, additional, Gaimari, Anna, additional, Nicolini, Fabio, additional, Mazza, Massimiliano, additional, Bravaccini, Sara, additional, Derudas, Daniele, additional, Martinelli, Giovanni, additional, and Cerchione, Claudio, additional

Published
2022
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9. Initial Surgical Strategy for the Treatment of Type A Acute Aortic Dissection: Does Proximal or Distal Extension of the Aortic Resection Influence the Outcomes?

Author

Bassano, Carlo, primary, Pugliese, Marta, additional, Mve Mvondo, Charles, additional, Pisano, Calogera, additional, Nardi, Paolo, additional, Buioni, Dario, additional, Bertoldo, Fabio, additional, Scognamiglio, Mattia, additional, Salvati, Alessandro C., additional, Altieri, Claudia, additional, and Ruvolo, Giovanni, additional

Published
2022
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10. Letermovir Prophylaxis for Cytomegalovirus Infection in Allogeneic Stem Cell Transplantation: A Real-World Experience

Author

Martino, Massimo, primary, Pitino, Annalisa, additional, Gori, Mercedes, additional, Bruno, Benedetto, additional, Crescimanno, Alessandra, additional, Federico, Vincenzo, additional, Picardi, Alessandra, additional, Tringali, Stefania, additional, Ingrosso, Claudia, additional, Carluccio, Paola, additional, Pastore, Domenico, additional, Musuraca, Gerardo, additional, Paviglianiti, Annalisa, additional, Vacca, Adriana, additional, Serio, Bianca, additional, Storti, Gabriella, additional, Mordini, Nicola, additional, Leotta, Salvatore, additional, Cimminiello, Michele, additional, Prezioso, Lucia, additional, Loteta, Barbara, additional, Ferreri, Anna, additional, Colasante, Fabrizia, additional, Merla, Emanuela, additional, Giaccone, Luisa, additional, Busca, Alessandro, additional, Musso, Maurizio, additional, Scalone, Renato, additional, Di Renzo, Nicola, additional, Marotta, Serena, additional, Mazza, Patrizio, additional, Musto, Pellegrino, additional, Attolico, Immacolata, additional, Selleri, Carmine, additional, Canale, Filippo Antonio, additional, Pugliese, Marta, additional, Tripepi, Giovanni, additional, Porto, Gaetana, additional, Martinelli, Giovanni, additional, Carella, Angelo Michele, additional, and Cerchione, Claudio, additional

Published
2021
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11. Netupitant/palonosetron without dexamethasone for preventing nausea and vomiting in patients with multiple myeloma receiving high-dose melphalan for autologous stem cell transplantation: a single-center experience

Author

Loteta, Barbara, primary, Paviglianiti, Annalisa, additional, Naso, Virginia, additional, Ferreri, Anna, additional, Moscato, Tiziana, additional, Console, Giuseppe, additional, Canale, Filippo Antonio, additional, Irrera, Giuseppe, additional, Pugliese, Marta, additional, Di Costanzo, Antonella, additional, Provenzano, Pasquale Fabio, additional, Loddo, Viviana, additional, Porto, Gaetana, additional, Cusumano, Giuseppa, additional, Russo, Letteria, additional, Meliambro, Nicola, additional, Romeo, Valentina, additional, Porcino, Domenico, additional, Gallo, Salvatore, additional, Gangemi, Tiziana, additional, Rossetti, Antonio Maria, additional, and Martino, Massimo, additional

Published
2021
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17. Mechanical Heart Valve Replacement in a Low-Middle Income Region in the Modern Era: Midterm Results from a Sub-Saharan Center.

Author

Mve Mvondo, Charles, Pugliese, Marta, Ambassa, Jean Claude, Giamberti, Alessandro, Bovio, Emanuele, and Dailor, Ellen

Subjects
*HEART valves, *MECHANICAL hearts, *AORTIC valve transplantation, *HEALTH facilities, *HOSPITAL mortality, *MITRAL valve
Abstract

Background The management of patients with mechanical heart valves remains a major concern in populations with limited resources and medical facilities. This study reports the clinical outcomes of patients who underwent mechanical valve implantation in a sub-Saharan center over an 8-year period. Methods A total of 291 mechanical valves were implanted in 233 patients in our institution between February 2008 and June 2016. A total of 117 patients underwent mitral valve replacement (MVR, 50.2%), 57 had aortic valve replacement (AVR, 24.4%), and 59 underwent both AVR and MVR (double valve replacement [DVR], 25.7%). The mean age at surgery was 27.6 ± 13.4 years (range, 7–62 years). Rheumatic etiology was found in 80.6% of the patients. Hospital mortality, late deaths, and valve-related events were reviewed at follow-up (839 patient-years, range: 1–9.4 years, complete in 93%). Results The 30-day mortality was 4.7% (11/233). The overall survival at 1 and 6 years for the whole cohort was 88.8 ± 2.1% and 78.7 ± 3.3%, respectively. The 6-year survival for AVR, MVR, and DVR was 89.3 ± 4.8%, 73.2 ± 5.4%, and 79.3 ± 5.8%, respectively (p = 0.15). The freedom from neurologic events and anticoagulation-related bleeding at 6 years was 93.1 ± 2.1% and 78.9 ± 3.7%, respectively. No patient had reoperation at follow-up. No case of prosthetic valve thrombosis was identified. Eight full-term pregnancies were reported. Conclusion This preliminary experience reports acceptable midterm results after mechanical heart valve implantation in our region. Both accurate surgical evaluation and strategies, either financial or social, facilitating patient's education and medical assistance are crucial to ensure good results. Long-term follow-up and further studies comparing current nonthrombogenic options are warranted to draw reliable conclusions. [ABSTRACT FROM AUTHOR]

Published
2020
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20. Neurologic Dysfunction after Aortic Dissection Surgery: Different Cerebral Hypothermic Antegrade Perfusion Techniques

Author

Bassano, Carlo, primary, Nardi, Paolo, additional, Colella, Dionisio Ferdinando, additional, Bovio, Emanuele, additional, Pugliese, Marta, additional, Russo, Marco, additional, Prati, Paolo, additional, Tartaglione, Alessandra, additional, Scaini, Roberto, additional, Scafuri, Antonio, additional, and Ruvolo, Giovanni, additional

Published
2018
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