23 results on '"Qian, Ming-Yang"'
Search Results
2. Key Regulatory Differentially Expressed Genes in the Blood of Atrial Septal Defect Children Treated With Occlusion Devices
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Li, Bo-Ning, primary, Tang, Quan-Dong, additional, Tan, Yan-Lian, additional, Yan, Liang, additional, Sun, Ling, additional, Guo, Wei-Bing, additional, Qian, Ming-Yang, additional, Chen, Allen, additional, Luo, Ying-Jun, additional, Zheng, Zhou-Xia, additional, Zhang, Zhi-Wei, additional, Jia, Hong-Ling, additional, and Liu, Cong, additional
- Published
- 2021
- Full Text
- View/download PDF
3. Transcatheter closure of coronary arterial fistula in children and adolescents
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Wang, Shu-Shui, Zhang, Zhi-Wei, Qian, Ming-Yang, Zhuang, Jian, and Zeng, Guo-Hong
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- 2014
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4. Screening of Genetic Syndromes by Facial Recognition Technology: VGG-16 Screening Model Construction and Evaluation
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Hong, Dian, primary, Zheng, Ying-yi, additional, Xin, Ying, additional, Sun, Ling, additional, Yang, Hang, additional, Lin, Min-yin, additional, Liu, Cong, additional, Li, Bo-ning, additional, Zhang, Zhi-wei, additional, Zhuang, Jian, additional, Qian, Ming-yang, additional, and Wang, Shu-shui, additional
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- 2021
- Full Text
- View/download PDF
5. Follow-up of percutaneous transcatheter closure of pulmonary arteriovenous fistulas
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Xi, Shi-Bing, primary, Xie, Yu-Mei, additional, Qian, Ming-Yang, additional, Shi, Ji-Jun, additional, Li, Yi-Fan, additional, and Zhang, Zhi-Wei, additional
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- 2019
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6. Predictors of operability in children with severe pulmonary hypertension associated with congenital heart disease
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Xi, Shi-Bing, primary, Wang, Shu-Shui, additional, Qian, Ming-Yang, additional, Xie, Yu-Mei, additional, Li, Jun-Jie, additional, and Zhang, Zhi-Wei, additional
- Published
- 2019
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7. Pediatric Hemorrhagic Stroke Complicates Interventions for Congenital Heart Disease: Experiences from Two Centers
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Xi, Shi-Bing, Xie, Yu-Mei, Li, Tao, Li, Yu-Fen, Qian, Ming-Yang, and Zhang, Zhi-Wei
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Heart Defects, Congenital ,Male ,Vascular Malformations ,lcsh:R ,Hemodynamics ,Infant ,lcsh:Medicine ,Stroke ,Risk Factors ,Child, Preschool ,Correspondence ,Humans ,Female ,Child ,Cerebral Hemorrhage - Published
- 2018
8. Immediate Therapeutic Outcomes and Medium-term Follow-up of Percutaneous Balloon Pulmonary Valvuloplasty in Infants with Pulmonary Valve Stenosis
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Hong, Dian, primary, Qian, Ming-Yang, additional, Zhang, Zhi-Wei, additional, Wang, Shu-Shui, additional, Li, Jun-Jie, additional, Li, Yi-Fan, additional, and Liu, Tian, additional
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- 2017
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9. Design of Microcontroller System for Surface Scanning of Micro-Steel Ball
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Qian Qian Wu, Ruo Feng Song, and Qian Ming Yang
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Surface (mathematics) ,Engineering ,business.industry ,Interface (computing) ,Surface scanning ,General Engineering ,Mechanical engineering ,Structural engineering ,Signal ,Core (optical fiber) ,Microcontroller ,Software ,Control system ,business ,ComputingMethodologies_COMPUTERGRAPHICS - Abstract
Based on the detection requirements of surface and sub-surface of micro steel ball, control system of defect scanning is studied, aiming at the problem of unfolded surface of steel ball, STC89S52 microcontroller is considered as the control core, then the feasible method of speed and direction control of step motor that driven by detection device, and hardware interface circuit and design of software solutions of the system are put forward, principles of unfolded surface of steel ball and control system of defect scanning and signal about defect scanning are analyzed, then the result are verified valid through the experiment. The results indicate that unfolded mechanics could be driven and flawed steel balls could be detected by the system of surface scanning of micro steel ball, which meet the design requirements.
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- 2013
10. Research on the Speed Synchronization Control Method of Double-HST Motor
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Qian Ming Yang, Ling Qi Kong, and Jian Li
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Constant linear velocity ,Float (project management) ,Software ,Computer science ,Control theory ,business.industry ,Control system ,Synchronization (computer science) ,PID controller ,Control engineering ,business ,Oil boom - Abstract
Embedded spilled oil recovery machine is one of the important mechanical equipment of oil spill emergency response and the speed synchronization of sweep arm end (float) and oil boom reel is the key technology of that. The problem of that line-speed synchronization of float and oil boom reel of embedded spilled oil recovery machine has been studied and the joint synchronization control scheme which adopt PID and equal control been also put forward in order to realize the speed coordination control of dual motor driven by HST with the PLC as the core of controller in this paper. The scheme of hardware design for the speed synchronization control system has been given and the software of the key technologies also been design and ran. The system speed has been simulated and analysis by MATLAB simulation software and the evaluation methods of the linear velocity errors been also put forward. Study in this paper provides reference for the follow-up projects and similar technical design. The stages of research results provide a reference for design work of the follow-up and similar technologies.
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- 2016
11. Simulation Analysis of Output Characteristic of the Inductive Displacement Transducer
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Qian Ming Yang, Li Ming Song, and Ruo Feng Song
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Nonlinear system ,Transducer ,Control theory ,Electromagnetic coil ,General Engineering ,Semidiameter ,Linearity ,Radius ,Displacement (vector) ,Mathematics ,Electromagnetic induction - Abstract
Aiming at the structure and electromagnetic induction characteristics of inductive displacement transducers, it is inevitable to appear the problem between nonlinearity output and temperature drift, by which it’s testing accuracy is affected, on the basis of analysis of structural characteristics and working principle of the inductive displacement sensor, mathematical model of the relationship between input and output has been constructed, which can be simulated and analyzed by MATLAB software. The results indicate that the inductive displacement transducer has an proximately linear extent ( ) and the linearity errors are influenced by the coils number and the semidiameter;In the case of relatively constant of other parameters, when the coil of radius and the number of coil turns are fixed ,there will be the core displacement x and , the sensor output characteristic has an favorable linearity under the circumstances of changing the coil radius and the number of turns in proper sequence; When ,the output property of the sensor appears worse linearity.
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- 2012
12. Application of Symmetrical Equations in Parametric Design of Involute Gear
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Qian Ming Yang, Su Tao Zhuang, and Yuan Yuan Ge
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Engineering ,Correctness ,business.industry ,Mathematical analysis ,General Engineering ,Structural engineering ,Physics::Classical Physics ,Involute gear ,Parametric design ,Involute ,Parametric model ,business ,Fillet (mechanics) ,Engineering design process - Abstract
Parametric design based on feature is the main method in parametric modeling of involute gear. In this paper, symmetric equations of the involute and the fillet curve are established according to the coordinates of points symmetrical about a straight line. And the tooth profile or alveolar profile of involute gear is generated accurately through controlling parameter of equations quantitatively. The problem of generating tooth profile accurately can be solved. Then the correctness of gear’s parametric design is ensured. The accuracy and efficiency of the gear’s engineering design are all improved.
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- 2012
13. Finite Element Analysis of Hydro-Viscous Drive Main Transmission Shaft Using ANSYS
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Re Feng So, Xiao Ming Wang, and Qian Ming Yang
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Engineering ,Cyclic stress ,Bearing (mechanical) ,business.industry ,Stress–strain curve ,General Engineering ,Mechanical engineering ,Structural engineering ,Finite element method ,law.invention ,Stress (mechanics) ,law ,Drive shaft ,business ,Focus (optics) ,Displacement (fluid) - Abstract
The main drive shaft is one of the key component of the Hydro-Viscous Drive device. The advantage or not of the mechanics performance as the shaft running became the focus of technology design since the complexity of structural design caused by complex function and the strain displacement caused by alternating stress in the condition of low-speed and heavy-duty. The mechanics analysis has been accomplished by the traditional way of mechanics and been proved by the ANSYS , as well as the orderliness of the stress and stain been obtained on the condition of bearing conditions in this paper. The result of the finite element analysis has offered the design reference for the shaft optimizing and pointed out that there was the biggest stress and strain value near the oil hole φ22 in the direction of radical.
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- 2011
14. Performance Analysis of CO2 Capture System by MEA Method Based on Solar Assisted Heat Pump Technology
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Yong Guo Luo and Qian Ming Yang
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Engineering ,Waste management ,Solar-assisted heat pump ,law ,business.industry ,Desorption ,Scientific method ,General Engineering ,Energy consumption ,business ,Process engineering ,Heat pump ,law.invention - Abstract
The MEA method basic process and CO2 capture system by the MEA method based on the lean solution source heat pump technology have been introduced. The desorption energy consumption of the system has been analyzed and caculated. The results show that heat pump technology combined with MEA method can reduce desorption energy consumption of system substantially. A new type of CO2 capture system by the MEA method with the solar-lean solution compound source heat pump providing desorption heat is put forward,whose thermodynamic performance is analyzed and the result indicates that desorption energy consumption can be decreased further by applying the solar assisted heat pump technology in the MEA method.
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- 2011
15. Optimization of Magnesium Separation and Extraction from Boron Slurry Using Response Surface Methodology
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Gao, Feng, primary, Fu, Rong, additional, Qian, Ming Yang, additional, Wang, Zhu Min, additional, and Zhang, Xiang, additional
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- 2011
- Full Text
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16. [Transcatheter interventional therapy of congenital heart disease: the results of Chinese TIT registry].
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Li JJ, Zhang ZW, Qian MY, Li YF, and Wang SS
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- Adolescent, Adult, Child, Child, Preschool, China epidemiology, Ductus Arteriosus, Patent surgery, Female, Heart Septal Defects, Atrial surgery, Heart Septal Defects, Ventricular surgery, Humans, Infant, Male, Middle Aged, Pulmonary Valve Stenosis surgery, Retrospective Studies, Young Adult, Cardiac Catheterization, Heart Defects, Congenital epidemiology, Heart Defects, Congenital surgery, Registries
- Abstract
Objective: To report the results of transcatheter interventional therapy (TIT) of congenital heart disease (CHD) register from 23 medical centers in China., Method: In this retrospective multicenter registry study, clinical data from 5808 patients who underwent TIT between January 2008 to December 2010 in 23 Chinese medical centers in 14 cities were analyzed., Results: Procedure was successful in 5720 cases (98.5%), success rate was 99.5% for PDA, 98.8% for ASD, 97.4% for VSD and 98.5% for pulmonary stenosis (PS). Multivariate regression analysis showed that PDA size and procedure time, age and procedure time, distance from VSD to AV were significantly associated with the procedure success rate of PDA, ASD and VSD closure, respectively. Early complications occurred in 306 cases (5.3%), 36 cases (0.6%) experienced major complications including device embolization in 7 cases, serious aorta regurgitation in 5 cases, serious tricuspid regurgitation in 4 cases, tricuspid stenosis in 2 cases, heart block (HB) in 13 cases (2 in ASD and 11 in VSD), cardiac tamponade in 2 cases (1 ASD and 1 PS) and hemolysis in 3 cases. Procedure time and PDA size, ASD size, device size, age and PS degree were risk factors related to the occurrence of the early complications for PDA, ASD and VSD closure and PBPV respectively. The median follow-up time was 15 months (range 1-36 months). The complete closure rate during follow up was 100% for ASD, PDA and VSD and the pressure gradient in PS decreased to normal range in all PS patients. Late complications occurred in 15 cases (0.2%), of which 3 cases needed surgery intervention and permanent pacemaker was implanted in 1 patient. There was no death during procedure and at follow-up period., Conclusions: TIT of CHD offers encouraging results in China. Follow up is warranted to monitor the occurrence of serious complications, especially late complications.
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- 2012
17. [Non-drug treatment for hypertrophic obstructive cardiomyopathy in children].
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Zhang X, Li YF, Xie B, Chen JY, and Qian MY
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- Adolescent, Cardiac Surgical Procedures, Cardiomyopathy, Hypertrophic therapy, Child, Female, Follow-Up Studies, Humans, Male, Cardiomyopathy, Hypertrophic surgery, Catheter Ablation
- Abstract
Objective: To retrospectively summarize the effect of non-medical therapies for pediatric patients with hypertrophic obstructive cardiomyopathy (HOCM)., Methods: From Nov. 2008 to Jun. 2010, 4 children with drug-refractory HOCM were admitted to our hospital. Their ages were 14, 7, 9 and 6 years old, respectively. Their body weights were 38, 17, 21.5 and 17 kg, respectively. Before operation, the pressure gradients over left ventricular outflow tract (LVOTG) were 60, 147, 58 and 114 mm Hg (1 mm Hg = 0.133 kPa), respectively. And mitral regurgitation (MR) areas were 2.2, 7.3 cm(2) and 2.9 cm(2), respectively, except that it was trivial in one case. Percutaneous transluminal septal myocardial ablation (PTSMA) was performed in case 1 and 2. Septal myectomy (SM) was performed in case 3 and 4. Follow-up was first performed right after operation or before discharge, then 1 month, 3 months, 6 months, and 12 months after operation, and then once a year. The follow-up period was 1 - 18 (9.3 ± 8.1) months., Results: All patients experienced relieved symptoms. Three of them had their NYHA functional class improved except case 2. Echocardiography revealed that LVOTGs right after operations were 38, 79, 20 and 0 mm Hg, respectively, suggesting significant improvement of left ventricular outflow tract obstruction (LVOTO) in all patients. During follow-up, case 2 suffered from recurrence of LVOTO, while the other 3 cases showed sustained relief. In the last follow-up, the LVOTGs of the four patients were 19, 168, 16 and 0 mm Hg, respectively. Echocardiography also revealed that MRs of all patients were significantly reduced, even in case 2 whose LVOTG rebounded, with no recurrence during follow-up. Severe complications were absent, such as ventricular septum perforation, cardiac tamponade, ventricular tachycardia or ventricular fibrillation. No one suffered from complete heart block. Transient complete right bundle branch block (CRBBB) was observed in case 1 after PTSMA and converted to intraventricular block after 1 month. Complete left bundle branch block (CLBBB) was present in both case 3 and 4, who received SM. In case 4, it converted to intraventricular block after 1 month while in case 3 CLBBB persisted., Conclusions: The initial experience showed that PTSMA and SM were safe and effective for drug-refractory symptomatic HOCM children, with satisfactory short-term results. Further studies are needed to evaluate the long-term results and complications.
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- 2011
18. [Interventional catheterization management for patients with postoperative residual cardiovascular malformations].
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Zhang ZW, Xie YM, Wang SS, Zhang X, Qian MY, and Li YF
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- Adolescent, Adult, Child, Child, Preschool, Female, Heart Defects, Congenital surgery, Humans, Infant, Male, Postoperative Period, Young Adult, Cardiac Catheterization, Heart Defects, Congenital therapy
- Abstract
Objective: To evaluate the efficacy of interventional therapy for complex congenital heart defects patients with un-repaired or postoperative residual lesions., Methods: Between March 1998 and April 2009, 42 patients (12 females), mean age 6 years (5 months to 30 years) received interventional therapy, 17 cases underwent occlusion of major aorto-pulmonary collateral arteries (MAPCAs), 15 underwent device closure of residual ventricular or atrial septal shunting, 12 underwent balloon angioplasty (n = 10) and stenting (n = 2) for stenosis of the anastomosis of vessels or branched pulmonary arteries., Results: Twenty-three MAPCAs were performed in 17 patients without residual shunting. One patient died of multiple organ failure after intervention therapy and the remaining patients discharged without complication, successful device closure was performed in 15 patients and there was minimal residual shunting in 1 patient. There were no severe arrhythmias such as complete atrio-ventricular block during and post procedure. Exercise capacities were significantly improved in 12 patients underwent balloon angioplasty or stenting. Pressure gradients were significantly decreased and there was no aneurysmal or thromboembolic formation post procedure., Conclusions: Interventional therapy is a safe and effective therapy option for treating complex congenital heart defects patients with un-repaired or postoperative residual lesions.
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- 2010
19. [Diagnosis and treatment of arrhythmogenic right ventricular cardiomyopathy in children].
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Wang SS, Zhang ZW, Xu YM, Jiang QP, Li H, Qian MY, and Li YF
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- Adolescent, Arrhythmogenic Right Ventricular Dysplasia drug therapy, Child, Child, Preschool, Echocardiography, Electrocardiography, Female, Humans, Male, Tomography, X-Ray Computed, Arrhythmogenic Right Ventricular Dysplasia diagnosis
- Abstract
Objective: To summarize the experience in diagnosis and treatment of arrhythmogenic right ventricular cardiomyopathy (ARVC) in children., Methods: A total of 14 children (7 females and 7 males) with ARVC were involved. The cases underwent electrocardiography, echocardiography, cardiac CT or MRI examinations. All cases were treated with sotalol or amiodarone in combination with propranolol. In 2 cases with drug-refractory ventricular extrasystoles, catheter ablation treatment was performed. In 6 cases with obvious impaired ventricular function, additional pharmacological therapy including vasodilators, diuretics, and digitalis were given., Results: Ventricular extrasystoles occurred in all 14 cases and ventricular tachycardia in 8 cases. Ten cases showed Epsilon wave on electrocardiography. All 14 cases had enlarged right ventricle and reduced right ventricular ejection fraction. CT or MRI examination showed right ventricular dilatation and a thinned wall of right ventricle in 10 cases. Ventricular extrasystoles or tachycardia disappeared in 7 cases and was reduced in 4 cases after treatment. The two children receiving catheter ablation treatment did not present ventricular extrasystoles or tachycardia in a 3-month follow-up. The heart function was improved in the 6 children with obvious impaired ventricular function after pharmacological therapy., Conclusions: The clinical manifestations are diverse in children with ARVC. A definite diagnosis of ARVC should be based on a combination of electrocardiography and echocardiography examinations. Pharmacological therapy is effective partially. Catheter ablation treatment appears to be a promising option in patients with drug-refractory ventricular extrasystoles.
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- 2010
20. [Early complications following transcatheter occlusion of perimembranous ventricular septal defects in children].
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Li JJ, Zhang ZW, Qian MY, Wang HS, and Li YF
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- Adolescent, Child, Child, Preschool, Female, Follow-Up Studies, Humans, Male, Prognosis, Retrospective Studies, Cardiac Catheterization adverse effects, Heart Septal Defects, Ventricular therapy, Postoperative Complications prevention & control
- Abstract
Objective: To evaluate the early complications during and after transcatheter closure of perimembranous ventricular septal defects (PMVSDs) in children., Methods: A total of 223 patients received transcatheter closure of PMVSDs from March 2002 to December 2005 in our hospital were included in this retrospective study., Results: The overall complications rate was 26.9% (60/223). Major complications occurred in 9 patients (4.0%) including III degrees atrioventricular block (AVB) in 2 (0.9%), hemolysis in 3 (1.3%) and surgical interventions in 4 patients (1.8%) because of device malposition (1), mild aortic regurgitation (2) and device embolization (1) and all 4 patients recovered without further complications. The 2 patients with III degrees AVB were completely recovered to normal sinus rhythm after 7 days treatment with temporary pacemaker and corticosteroid. Hemolysis in 3 patients disappeared after corticosteroid treatment. Minor complications occurred in 51 patients (22.8%) including bundle branch block (BBB) in 37 (16.6%), first-degree AVB in 2 (0.9%), second-degree AVB in 1 (0.4%), new-onset mild aortic regurgitation in 5 (2.2%) and new-onset mild to moderate tricuspid regurgitation in 6 patients (2.6%). Except for right bundle branch blocks, other BBBs were treated with albumin and corticosteroid and completely recovered. No treatment was applied for new-onset valve regurgitations. There was no death in all 223 patients., Conclusions: Early complications post PMVSDs in children are mostly minor with good prognosis and the prognosis for major complications post PMVSDs is good after proper treatment.
- Published
- 2006
21. [Management of the arrhythmia around the procedure of transcatheter closure of ventricular septal defects in pediatric patients].
- Author
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Xie YM, Zhang ZW, Li YF, Qian MY, and Wang HS
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- Adolescent, Cardiac Catheterization adverse effects, Child, Child, Preschool, Female, Heart Septal Defects, Ventricular surgery, Humans, Male, Arrhythmias, Cardiac therapy, Cardiac Catheterization methods
- Abstract
Objective: To discuss the treatment of arrhythmia occurs in the process of transcatheter closure of perimembranous ventricular septal defects (VSD) in pediatric patients., Methods: 182 cases (mean age: 6.2 +/- 3.3 years) with membranous VSD underwent transcatheter occlusion procedure. Two different devices were used: the Amplatzer membranous VSD occluder in 81 patients and the domestic-made device in 101 patients. Electrocardiogram of all patients was recorded before and during closure and at one day after the procedure, and Holter monitoring was performed one week after the procedure., Results: Perioperation arrhythmia occurred in thirty-one patients (17%). Second- or third-degree atrioventricular bundle (AVB) was noted during the procedure in four patients. Normal AV conduction recovered spontaneously before the catheters were withdrawn in three cases and another patient underwent surgical repair. In the other twenty-seven patients, arrhythmia was first documented between one day and one week after the procedure. Third-degree AVB was found in three (1.6%) children after the procedure and underwent the temporary pacemaker (TPM) was implanted, two of them recovered to normal sinus rhythm within one week, another patient underwent elective surgery to remove the occluder and repair the defect. Other arrhythmias were: left bundle-branch block (n = 3), right bundle-branch block (n = 12), second-degree AVB (n = 2), sinus tachycardia (n = 6)., Conclusions: In properly selected cases of perimembranous VSD, the transcatheter closure is safe and effective by using appropriate devices. During and after the procedure, closure of VSD can be associated with some kinds of arrhythmia, such as A-V block, more intensive observation and follow-up were therefore needed.
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- 2005
22. [A follow-up study on transcatheter closure of patent ductus arteriosus with Amplatzer duct occluder in children].
- Author
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Li JJ, Li YF, Zhang ZW, Qian MY, and Wang HS
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- Adolescent, Balloon Occlusion adverse effects, Balloon Occlusion methods, Cardiac Catheterization, Child, Child, Preschool, Ductus Arteriosus, Patent diagnostic imaging, Echocardiography, Doppler, Color, Female, Follow-Up Studies, Hemolysis, Humans, Infant, Male, Radiography, Interventional, Retrospective Studies, Time Factors, Treatment Outcome, Balloon Occlusion instrumentation, Ductus Arteriosus, Patent therapy, Embolization, Therapeutic adverse effects, Embolization, Therapeutic methods
- Abstract
Objective: To document the five-year follow-up results of transcatheter Amplatzer duct occluder (ADO) occlusion of patent ductus arteriosus (PDA) in children and to assess the safety and effectiveness of this method for PDA closure., Methods: A retrospective cohort study was completed in patients with PDA underwent transcatheter closure by the ADO in Guangdong Cardiovascular Institute from April 1998 to December 2003., Results: Transcatheter closure of PDA with ADO was attempted in 250 children patients. The median age was 5.3 years and median weight was 15.1 kg. The PDAs were from 1.8 mm to 11.0 mm (median 4.2 mm) in the narrowest diameter, of which 52 were larger than 5 mm (20.0%). All PDAs were occluded with 4 approximately 14 mm ADO through 6F (n = 205) or 7F (n = 45) sheaths. Devices were successfully implanted in 245 patients (98.0%). The Qp/Qs decreased from 1.90 +/- 0.60 to 1.03 +/- 0.21 (P < 0.05). All shapes of the PDA could be closed. Late complication occurred in five patients, including hemolysis in three patients and the los of the pulse of femoral artery in two patients. Follow-up after device implantation was accomplished in 205 patients (82.0%). The incidence of residual shunt at follow-up periods of 1 d, 1 m, 6 m, 12 m, 24 m, 36 m, 48m and 60 m after device occlusion was 9.2%, 2.8%, 1.2%, 0.8%, 0, 0, 0 and 0, respectively. Five patients (2.0%) required re-intervention to treat residual shunt with or without hemolysis. Event-free rates were 98.0% at one year and five years., Conclusion: This long-term follow-up result confirmed the safety and effectiveness of ADO closure of PDAs in children.
- Published
- 2005
23. [Applying interventional treatment for the atrial septal defect in 165 children under five years of age].
- Author
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Wang HS, Qian MY, Zhang ZW, Zeng SY, Xie YM, and Li YF
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- Child, Preschool, Echocardiography, Female, Heart Septal Defects, Atrial diagnostic imaging, Humans, Male, Heart Septal Defects, Atrial surgery, Septal Occluder Device adverse effects
- Abstract
Objective: To study the clinical technology of transcatheter closure of secundum atrial septal defects (ASD) with Amplatzer device in younger and lower body weight children., Methods: The transcatheter closure of ASD using Amplatzer septal occluder (ASO) was performed in 165 children under 5 years of age (75 boys and 90 girls) with secundum ASD from Aug 1998 to May 2004. The age of the cases ranged from 2 to 5 (mean 3.7 +/- 1.1) years. The body weight ranged from 9 to 18 (mean 12.6 +/- 2.3) kg. The ratio of pulmonary circulation quantity to the systemic circulation quantity (Qp/Qs) was 3.2 +/- 1.9. All the patients underwent clinical examination, X-ray, electrocardiography (ECG) and echocardiography (Echo) for diagnosis of secundum ASD. The transthoracic echocardiography (TTE) was used to detect and measure the defect of the patients and even trans-esophageal echocardiography (TEE) had to be used when it was necessary. With Echo and X-ray guidance, the measuring balloon was used in the body and outside the body to determine the balloon-stretch diameters of ASD, and proper occluders were selected accordingly for the patients for interventional treatment of ASD., Results: The devices were implanted successfully in 163 (98.8%) cases. One failure occurred in a case in whom the device moved into the left atrium after release, and the other failure was that the position of the device was uncertain because of temporary unavailability of a special transducer for TEE. Surgical operations were performed for these two cases. The stretch diameter of ASD was from (8 - 30) mm, (mean 18.3 +/- 5.1) mm. The size of device was selected according to the stretch diameter of ASD. The diameter of the occluders selected was from (8 - 30), (mean 18.6 +/- 5) mm in this series. The occlusion procedure was monitored by fluoroscopy and TTE and in 5 cases (3%) by TEE. The diameter of right ventricle was improved within 2 days after occlusion from (mean 16.4 +/- 4.9) mm to (mean 12.6 +/- 3.8) mm, (p < 0.01). One hundred and forty seven cases belonged to the simple secundum ASD(89%). Thirteen cases who were complicated with other cardiac deformity were treated successfully with different interventional procedure. Six cases had multiple openings and three of these cases had tumour-like changes of the atrial septum which were closed completely just by one occluder. In only one case small quantity of residual shunt remains. No other severe complication was found in this group. About 100 cases (60%) had large ASD, so the procedure was more difficult in those cases., Conclusion: The clinical effectiveness of treatment of ASD in children under 5 years of age with Amplatzer occluders was satisfactory and therefore this therapeutic procedure is feasible for this age group of patients. Nevertheless, we do not recommend to use the technique for infants and children under 2 years of age. Strict selection of indications and proper size of occluder and good cardiologic and surgical settings are among the basic factors for successful interventional occlusion of ASD in young children.
- Published
- 2005
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