1. Comparative analysis of oral saliva microbiomes and metabolites in Han population at different altitudes
- Author
-
Junping Li, Lamu Suonan, Jiangsong Lin, Jiangcuo Zhaxi, Ming Gong, Jian Li, Dawa Langjie, Lulu Zhu, Qiangjiu Shique, and Cheng Chen
- Subjects
high-altitude ,microbiomes ,metabolites ,16S rRNA gene sequencing ,non-targeted metabolomics ,saliva ,Microbiology ,QR1-502 - Abstract
ObjectiveThis study investigated the differences in oral saliva microbiota composition and metabolic products among Han Chinese populations living at different altitudes, as well as their correlations.MethodThe analysis was conducted using the 16S rRNA gene sequencing method and untargeted metabolomics.Results16S gene sequencing results showed significant differences in bacterial diversity and composition between HH (High altitude Han) group and LH (Low altitude Han) group. LEfSe analysis showed that Selenomonas, Leptotrichia, Veillonella, Prevotella relatively abundant are higher in HH group, Haemophilus, Neisseria, Actinobacillus, Aggregatibacter are higher in LH group (p
- Published
- 2024
- Full Text
- View/download PDF