Search

Exercise intervention as a key prevention and treatment strategy for type 2 diabetes mellitus (T2DM) has been generally accepted worldwide. Unfortunately, the "one-size-fits-all" interventions recommended by various physical activity guidelines do not result in the same benefits for all patients. The reasons are: first, the etiology, pathogenesis and clinical manifestations of T2DM are highly heterogeneous; second, the response of T2DM patients to exercise intervention is heterogeneous. These two heterogeneities affect the effectiveness of exercise intervention in T2DM, and to improve the effectiveness, precise typing and precise intervention for diabetes are required. Therefore, it is necessary to understand the principle and implementation process of precision motion intervention. In this review. we summarize the molecular genetic basis of T2DM, the molecular mechanism of exercise intervention, and the heterogeneity of patients' response to exercise, and comment on the current research progress in accurate typing, diagnosis, treatment, and monitoring of T2DM., focusing on the causes and mechanisms of individual differences in T2DM patients' response to exercise, and put forward suggestions for using exercise prescription parameters as key variables in the precise treatment of T2DM. [ABSTRACT FROM AUTHOR]

The beneficial effects of exercise on health are well documented by evidence-based medicine, and it has been suggested that the health promotion of exercise is at least in part attributable to the "crosstalk" or "interaction" between organs (tissues) caused by exerkines released into the circulation by organs (tissues) during exercise. The classification, function and mechanism of exerkines are summarized, and the relationship between the myokines, adipokines, osteokines and hepatokines released by exercise and the occurrence and development of diseases is explained. It is believed that exercise-induced myokines, adipokines, osteokines and hepatokines can have a wide range of effects on the shape, structure, function and metabolism of the human body through "self-crosstalk" and "crosstalk" between organs (tissues) and organs (tissues), and participate in the maintenance of individual health. The effect of this crosstalk depends on the form of exercise, exercise intensity, exercise duration, exercise frequency and other factors. The conclusions can provide a new perspective for the understanding of the mechanism of exercise health promotion. [ABSTRACT FROM AUTHOR]

In order to fully understand the current status of the Chinese citizens' awareness of sports, its influencing factors, and exploring effective countermeasures, a questionnaire survey was conducted to 6 058 Chinese citizens aged from 18 to 69 living in 31 provinces, municipalities and autonomous regions across the country, except for Hong Kong, Macau and Taiwan. The results showed that the citizens with sports awareness only accounted for 19.69% of those surveyed. The average score of the Chinese citizens' comprehensive sports awareness index was 60.83 and the overall level was low. The level of sports awareness of group citizens of different gender, age, educational background, income, occupation, and self-evaluation health status was uneven. At the level of sports awareness, male citizens were significantly higher than female citizens. Citizens in the 18~29 age group had significantly higher sports consciousness than citizens in other age groups. It was the same case for urban residents vs rural residents. It was shown that the higher educational background, the higher sports consciousness. State personnel, university student, technical staff had higher sports consciousness than people of other occupations. As for people with monthly payment higher than RMB 2 000, the higher the monthly income was, the higher sports consciousness was. There was an imbalanced development with regard to the different dimension and factors of sports consciousness. People were highly approved of sports while their sports consciousness and participation was not enough. [ABSTRACT FROM AUTHOR]