1. Acute Bioprosthetic Mitral Valve Thrombosis: An Unfortunate Collision of Prothrombotic Risk Factors.
- Author
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Quattrocchi NM, Hemli JM, Scheinerman SJ, and Patel NC
- Subjects
- Acute Disease, Adult, Female, Fertility Agents, Female administration & dosage, Heart Valve Diseases diagnostic imaging, Heart Valve Diseases surgery, Humans, Leuprolide administration & dosage, Reoperation, Risk Factors, Thrombosis diagnostic imaging, Thrombosis surgery, Bioprosthesis adverse effects, Fertilization in Vitro adverse effects, Heart Valve Diseases etiology, Heart Valve Prosthesis adverse effects, Mitral Valve surgery, Protein C Deficiency complications, Thrombosis etiology
- Abstract
Subclinical and clinical thrombosis of bioprosthetic cardiac valves is more common than has been previously recognized. We present a unique case of acute thrombosis of a bioprosthetic mitral valve in a 40-year-old female patient undergoing hormonal stimulation as part of in vitro fertilization therapy, who also had concomitant protein C deficiency that was undiagnosed at the time. To the best of our knowledge, this is the first reported case of acute bioprosthetic valve thrombosis in this complex thrombophilic milieu, and suggests the need for increased screening for prothrombotic risk factors in female patients with bioprosthetic valves before they commence gonadotropin stimulation therapy., (2019 Forum Multimedia Publishing, LLC)
- Published
- 2019
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