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The neuropsychiatric manifestations of SLE are varied and may be classified as primary neurologic and psychiatric disease (related to direct involvement of the nervous system] or secondary disease (related to complications of the disease and its treatment), Estimates of the prevalence of neuropsychiatric manifestations o f SLE have ranged from 14% to over 80% in adults. The wide range in reported prevalence reflects in part the use of different criteria for neuropsychiatric disease. It seems that 28-40% of these manifestations develop before or around the time of the diagnosis of SLE. Our poster will focus on the clinical presentation, diagnosis and treatment strategies of neuropsychiatric lupus (NPSLE) in a series of 5 recent cases. [ABSTRACT FROM AUTHOR]

Orbital myositis is a rare autoimmune disorder which affects the extraocular muscles and is usually associated with a variety of non-infectfous diseases (eg: unspecific idiopathic inflammation, vasculitis, sarcoidosis, Crohn's disease), thyroid-related eye disease, infections (eg: Herpes Zoster, Lyme disease, Cysticercosis, infections of the upper respiratory tract and sinus), neoplasms. A complete an accurate diagnostic can be a very challenging process, needing the cooperation o f a multidisciplinary team in order to achieve a faster diagnosis and better treatment options. For this reason, our poster tries to present a synthesis of the latest reports regarding the clinical and paracltnica! diagnostic algor hythm of this disease, together w ith a recent controversial case presentation. [ABSTRACT FROM AUTHOR]