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A survey to assess injection related practices carried out among the Nicobarese, a mongoloid tribe of Andaman and Nicobar Islands, India. The survey was carried out using the rapid assessment and response guide of Safe Injection Global Network of the World Health Organization and included review of randomly selected prescriptions of patients attending outpatient clinic of district hospital, interview and observation of injection providers in the district hospital and sub-centres and interview of the general population. The findings of the survey showed that 18.8% of prescriptions included at least one injection. The per capita injection rate was 3 per year. Majority of injections were administered with disposable syringe and needle and in hospital setting. All the injection providers were aware about possibility of HIV transmission through unsafe injections. However, the awareness among the general population was low. More than half of the individuals had preference to injections. It is suggested that remedial measures, such as education of prescribers to reduce the number of injections to a bare minimum, maintaining regular supply of disposable injection equipment, provision of adequate sharps containers with safe disposal facilities and community education be undertaken to avoid future spread of blood-borne pathogens.

The premise of this paper is to provide an understanding of two very similar analytical test methods that are often used in corporate quality control testing: the differential scanning calorimetry (DSC) test and the shrink temperature test. In this study, a collagen-based product was subjected to these two analytical methods. The results indicated that there is no significant difference in using either method in obtaining the melting temperatures of the test articles. The pros and cons of each method were also discussed in this article.

C 26 H 32 NO 6 S 2 Cl cristallise dans P2 1 2 1 2 1 avec affinement jusqu'a 0,031. La partie A, module camphosulfonate a la configuration R et la partie B a la configuration S

In some cases the use of classical methods of melting point determination may lead to erroneous interpretation of the data obtained. The main sources of errors are the presence of polymorphic or pseudo-polymorphic modifications, and the thermal instability of the solid, which may decompose without melting. The present work was aimed at demonstrating the utility of using Differential Scanning Calorimetry (DSC) and Thermogravimetry (TG) in the critical evaluation of melting point data obtained from the more classical methods recommended by the European Pharmacopoeia.

Presentation de la methode, ne faisant pas appel a un second synthetiseur et application au spectre RMN de 13 C d'un melange de α- et β-D-glucopyrannose