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The purpose of this study was to perform the oestrus induction and synchronization of Saanen goats in outof-season. The study was conducted from July 2014 - April 2015 on 77 Saanen goats, aged between 1.5 to 5 years. The goats were divided into three experimental groups: in group I (n =37 goats) intravaginal sponge (Ovigest) containing 60 mg of MPA was left in the vagina for 14 days. Immediately after sponge removal the animals received two injections: 0.75 mg (1 ml) prostaglandin (Prosolvin) and 500 IU PMSG hormone (Folligon). In group II (n=20) oestrus induction and synchronization was performed using synthetic prostaglandin (Proliz - 1 ml containing 0.2 mg isopropyl ester of cloprostenol and 9 mg benzyl alcohol) at the dose of 0.5 ml/animal. The group III (n=20) was considered the control group and oestrus synchronization was performed using fertile bucks. In group I the results showed that all goats expressed signs of oestrus. The average value of the oestrus interval was 33 hours and the average of oestrus duration was 20 hours. The number of kids obtained in group I was 94, and prolificacy was P (%) = 2.54. In group II and III was not observed occurrence of oestrus. Synchronization practice is necessary, due to a significant positive effect on oestrus and fecundity. [ABSTRACT FROM AUTHOR]