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Canine babesiosis is one of the most important vector-borne diseases worldwide that affects dogs regardless of age, breed or gender. The aim of this study was to corroborate the clinical signs of canine patients confirmed with babesiosis, the results of paraclinical investigations, as well as the choice of the therapeutic protocol. The present study was performed on 42 dogs referred to the Clinic of Parasitic Diseases from the Faculty of Veterinary Medicine of Iasi with similar symptoms to canine babesiosis. After recording data regarding age, breed and gender of all dogs and the clinical examination of the patients, two peripheral blood samples were collected from each patient for the following investigations: Diff-quick stained blood smears and blood tests (hematological, biochemical, serologic). After analysis of blood smear, all the dogs (42/42) were positive for Babesia spp. and the most common clinical signs identified were: fever - 37/42 (88,1%), pale mucous membrane - 31/42 (73,8%) and hemoglobinuria - 31/42 (73,8%). The results of hematologic tests revealed thrombocythopenia - 40/42 and moderate to severe anemia. Further serological tests detected Babesia gibsoni antibodies in 2/42 blood samples. Depending on the results of the blood tests, the therapeutic dose of imizole was administered in a single dose or divided into two doses, administered within a maximum of 12 hours. In conclusion, the present study emphasizes the importance of paraclinical investigations in order to identify possible co-infections and adjust treatment in infected dogs. [ABSTRACT FROM AUTHOR]

Sarcoptic mange in dog is a common parasitic dermatitis, especially in non-controlled, stray dogs that develop evocative clinical signs. The present study includes 48 dogs, with different backgrounds, both privately owned and dogs from shelters. We searched for predisposing factors for contacting sarcoptic mange, such as: age, sex, breed, source of contamination. Their age ranged from 1.15 months to 12 years (with more than a half being under 1 year old), they were mostly common or cross-breed dogs, and the sex ratio was almost equal, with 25 females and 23 males. All dogs were naturally infected with Sarcoptes scabiei, as confirmed by identification on the microscope of skin scrapings from different body areas. Furthermore, we aimed to have a general idea concerning the severity of infection with Sarcoptes scabiei in the dogs we studied. The dogs received a clinical score based on the evaluation of typical signs that appear in sarcoptic mange such as alopecia, erythema, scales/crusts and the extent of mange on the cutaneous surface on different body parts (head, trunk, legs, tail). The most affected body part was the head, followed by the trunk and the most scored sign was the extent of affected skin and alopecia. The treatment consisted in the administration of either afoxolaner (Nexgard®), twice at a monthly interval (2.7-6.9 mg/kg), either sarolaner (Simparica®), twice at a monthly interval (2-4 mg/kg), or doramectin (Dectomax®) 0.2 mg/kg, twice at 14 days interval. [ABSTRACT FROM AUTHOR]

The aim of this study was to explore the efficacy of a veterinary drug, Diminazene aceturate (4,4'-(1-Triazene- 1,3-dyil)-bis-(benzenecarboximidamide), in an inclusion complex with ß-cyclodextrin as a suitable treatment for parasitic diseases caused by Ichthyophthirius multifiliis in farmed carp. The efficacy was determined by the reduction in the infection intensity. The complexes were prepared by the coevaporation method and were characterized by DSC and FTIR. The selected stoichoimetry for the chosen drug was 1:1. Administration of Diminazene aceturate and complex was carried out by including appropriate doses in animal feed. Our studies suggest that the Diminazene-ß-cyclodextrin complex results in a reduction in the infection degree and decrease in the trophont size in the treated fish. The oral treatment of Diminazene aceturate in inclusion complexes may be an alternative to bath treatments in carp farming. [ABSTRACT FROM AUTHOR]

The histophagous ciliate Ichthyophthyrius multifiliis can cause lethality in farmed carp brood (Cyprinus carpio) as well as other representatives. In the present study, an antiparasitic substance (diminazene aceturate) and its complex with a cyclodextrin were tested for its activity against this pathogen in vitro. The purpose of this paper is to highlight the therapeutic potential of diminazene and the enhancement by the ß-cyclodextrin. Of these, the complex proved to be more effective (i.e., killed all parasites in a test period of 6-8 hours). Administration in filtered water suggests that these compounds can not be effective in bathing. In view of these findings, we will discuss the potential utility of chemotherapy as a strategy for controlling ciliatosis in farmed fish. [ABSTRACT FROM AUTHOR]

The paper presents a mechatronic system programmed and controlled by a PLC and inverter for driving an ac motor. Torque and speed for part of mechatronic systems depends of actuating source for cinematic structure. In our research, mechanical structure consists of an AC motor. A technique for setting and control of speed and torque is presented. [ABSTRACT FROM AUTHOR]