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1. Prevalence of hypertriglyceridemia in adults and related cardiometabolic factors. SIMETAP-HTG study

Author

M.J. Frías Vargas, N. Zarzuelo Martín, Diana Fernández-Pacheco Vila, J.L. Velazco Zumarrán, M. Sánchez Herráiz, E. Revilla Pascual, M.C. Sánchez Ramos, A.P. Javierre Miranda, M. Inmaculada Hernández-Beltrán, A. Alcaraz Bethencourt, A.O. Rodríguez, Manuel J. Frías-Vargas, J.L. Quintana Gómez, C. Sanz Velasco, L. Ruiz Díaz, M.J. del Villar Redondo, R.A. Escrivá Ferrairó, R. Pleite Raposo, A.I. Macho del Barrio, Gema M. Dávila-Blázquez, M. del Carmen Antón-Sanz, P. Cabello Igual, R. Hueso Quesada, S. Redondo de Pedro, C. Zafra Urango, R.M. Hernández López, Antonio Sánchez-Calso, J.R. Iglesias Quintana, M. Redondo Sánchez, B. López Uriarte, A. Migueláñez Valero, R. Pérez Muñoz, A. Montero Costa, N. Escamilla Guijarro, Montserrat Pérez Fernández, T.F. Casaseca Calvo, D. Fernández-Pacheco Vila, Santiago Delgado Rodríguez, A.I. Martín Fernández, M.C. Vieira Pascual, M.S. Moreno Muñoz, P.L. Sanchidrián Fernández, M.R. Durán Tejada, E. Arranz Martínez, S. Delgado Rodríguez, M.T. Sarriá Sánchez, A. Rodríguez de Cossío, M.D. García Granado, M.P. Hombrados Gonzalo, S. Luna Ramírez, R. Alonso Roca, I. Tello Meco, M. Pérez Fernández, L.E. Morales Cobos, T. Pascual Val, N. de la Peña Antón, M. Rubio Villar, P. Aguilera Reija, C. Vargas-Machuca Cabañero, R. Rodríguez Cabanillas, A.M. Ibarra Sánchez, M. Rosario Morales-Chico, M.C. Hernández de Luna, E. Rodríguez de Mingo, C. Ribot Catalá, M.P. García Alcañiz, N. Caballero Ramírez, P. Simonaggio Stancampiano, M. Rivera Teijido, Rafael Alonso-Roca, M.S. Holgado Catalán, E. Gómez Díaz, Montserrat Rivera-Teijido, Raquel Pleite Raposo, Isabel Tello-Meco, E. Barrios Rueda, Beatriz López-Uriarte, José Antonio González-Posada Delgado, J.A. González-Posada Delgado, C. Abad Schilling, N. Marañón Henrich, Ana Olga Rodríguez Rodríguez, R. Álvarez Benedicto, N. Iturmendi Martínez, J. Reguillo Díaz, M.M. Zamora Gómez, M.P. Calderín Morales, R. Cabrera Vélez, Ana Pilar Javierre-Miranda, Joaquina Reguillo-Díaz, Beatriz Remón-Pérez, José Luis Quintana-Gómez, B. Sanz Pozo, M.R. Morales Chico, E. Martínez Cid de Rivera, M.P. García Villasur, J.M. Blanco Canseco, Y. Hidalgo Calleja, A. Rosillo González, M. Isabel Gutiérrez Sánchez, C. Mora Casado, M. Capitán Caldas, M.C. Martín Calle, E. Sandín de Vega, Paloma Aguilera Reija, P. González Escobar, Ignacio Íscar-Valenzuela, M.I. Hernández Beltrán, M.T. Plata Barajas, Juan Ramón Iglesias Quintana, M.E. García Fernández, J.C. Moreno Fernández, C. Ciria de Pablo, P. Arribas Álvaro, Enrique Revilla-Pascual, M.R. García Redondo, Antonio Rosillo-González, P. Magán Tapia, Antonio Ruiz-García, Rosa Ana Escrivá-Ferrairó, I. Gutiérrez Sánchez, M.C. Díez Pérez, Raúl Pérez Muñoz, I. Íscar Valenzuela, Ofelia Gómez-Fernández, B. Remón Pérez, J.E. Mariño Suárez, T. Fernández Vicente, M. Prieto Marcos, A. Ruiz García, M.S. Lorenzo Borda, M.C. Baltuille Aller, David Palacios-Martínez, Ana María Ibarra-Sánchez, R.A. García Pliego, M. Adrián Sanz, José Enrique Mariño-Suárez, O. Gómez Fernández, M. Jesús del Villar Redondo, J.A. Cique Herráinz, Norma Alejandra Doria-Carlin, M.R. Rico Pérez, P. Chao Escuer, A.M. Rey López, Ezequiel Arranz-Martínez, A. Sánchez Calso, J. Martínez Irazusta, D. Palacios Martínez, E. Benito Alonso, M.E. Minguela Puras, Rafael Rodríguez-Cabanillas, Elena Barrios-Rueda, J.C. García Álvarez, Miguel Prieto Marcos, G. Dávila Blázquez, L. de Prado Prieto, and M.L. Berbil Bautista

Subjects
medicine.medical_specialty, Multivariate analysis, Triglyceride, business.industry, Hypertriglyceridemia, General Engineering, Prevalence, medicine.disease, Obesity, chemistry.chemical_compound, chemistry, Diabetes mellitus, Internal medicine, medicine, General Earth and Planetary Sciences, Steatosis, business, General Environmental Science, Kidney disease
Abstract

Aim To determine in the adult population the crude and the sex- and age-adjusted prevalence rates of hypertriglyceridaemia (HTG) and to assess its association with cardiovascular risk factors, chronic kidney disease, cardiovascular and cardiometabolic diseases. Methods Cross-sectional observational study conducted in Primary Care, with 6,588 adult study subjects, randomly selected on base-population. Patients had HTG if the triglyceride level was ≥150 mg/dL (≥1.7 mmol/L), or were on lipid-lowering therapy to lower triglyceride. Associations were assessed by univariate and multivariate analysis, and crude and sex- and age-adjusted prevalence rates were determined. Results The arithmetic and geometric means of triglyceride levels were respectively 120.5 and 104.2 mg/dL in global population, 135.7 and 116.0 mg/dL in men, and 108.6 and 95.7 mg/dL in women. The crude HTG prevalence rates were 29.6% in global population, 36.9% in men and 23.8% in women. The sex- and age-adjusted HTG prevalence rates were 27.0% in global population, 34.6% in men and 21.4% in women. The independent variables that were most associated with HTG were hypercholesterolemia (OR: 4.6), low HDL-C (OR: 4.1), hepatic steatosis (OR: 2.8), diabetes (OR: 2.0), and obesity. (OR: 1.9). Conclusions The means of triglyceride levels and HTG prevalence rates are intermediate between those of other national and international studies. A fifth of the female adult population and more than a third of the male population had HTG. The independent factors associated with HTG were hypercholesterolemia and low HDL-C, and the cardiometabolic variables diabetes, hepatic steatosis and obesity.

Published
2020
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2. Prevalencia de hipertrigliceridemia en adultos y factores cardiometabólicos asociados. Estudio SIMETAP-HTG

Author

M. Jesús del Villar Redondo, Raúl Pérez Muñoz, José Antonio González-Posada Delgado, Antonio Ruiz-García, Juan Ramón Iglesias Quintana, Paloma Aguilera Reija, Ezequiel Arranz-Martínez, Enrique Revilla-Pascual, Diana Fernández-Pacheco Vila, Beatriz Remón-Pérez, Elena Barrios-Rueda, Gema M. Dávila-Blázquez, Montserrat Rivera-Teijido, Ana María Ibarra-Sánchez, Norma A. Doria-Carlin, Ignacio Íscar-Valenzuela, José Enrique Mariño-Suárez, Beatriz López-Uriarte, Isabel Tello-Meco, Raquel Pleite Raposo, Joaquina Reguillo-Díaz, Rafael Alonso-Roca, Antonio Rosillo-González, Rosa Ana Escrivá-Ferrairó, M. del Carmen Antón-Sanz, José Luis Quintana-Gómez, Ana Olga Rodríguez Rodríguez, D. Palacios-Martínez, Santiago Delgado Rodríguez, Montserrat Pérez Fernández, M. Isabel Gutiérrez Sánchez, M. Rosario Morales-Chico, M. Inmaculada Hernández-Beltrán, Rafael Rodríguez-Cabanillas, Ofelia Gómez-Fernández, Antonio Sánchez-Calso, Ana Pilar Javierre-Miranda, Manuel J. Frías-Vargas, and Miguel Prieto Marcos

Subjects
03 medical and health sciences, 0302 clinical medicine, Pharmacology (medical), 030212 general & internal medicine, 030204 cardiovascular system & hematology, Cardiology and Cardiovascular Medicine
Abstract

Resumen Objetivo Determinar en la poblacion adulta las tasas de prevalencia brutas y ajustadas por edad y sexo de hipertrigliceridemia (HTG) y valorar su asociacion con factores de riesgo cardiovascular, enfermedad renal cronica y enfermedades cardiovasculares y cardiometabolicas. Metodos Estudio observacional transversal realizado en Atencion Primaria, con 6.588 sujetos de estudio adultos, seleccionados aleatoriamente con base poblacional. Los pacientes tenian HTG si la concentracion de trigliceridos era ≥ 150 mg/dL (≥ 1,7 mmol/L) o estaban en tratamiento hipolipidemiante para reducir los trigliceridos. Se valoraron las asociaciones mediante analisis univariado y multivariante, y se determinaron las prevalencias brutas y ajustadas por edad y sexo. Resultados Las medias aritmeticas y geometricas de las concentraciones de trigliceridos fueron respectivamente 120,5 y 104,2 mg/dL en la poblacion global, 135,7 y 116,0 mg/dL en hombres, y 108,6 y 95,7 mg/dL en mujeres. Las prevalencias brutas de HTG fueron 29,6% en poblacion global, 36,9% en hombres y 23,8% en mujeres. Las prevalencias ajustadas por edad y sexo de HTG fueron 27,0% en poblacion global, 34,6% en hombres y 21,4% en mujeres. Las variables independientes que mas se asociaban con la HTG fueron hipercolesterolemia (OR: 4,6), c-HDL bajo (OR: 4,1), esteatosis hepatica (OR: 2,8), diabetes (OR: 2,0) y obesidad (OR: 1,9). Conclusiones Las medias de trigliceridos y las prevalencias de HTG se encuentran intermedias entre las de otros estudios nacionales e internacionales. La quinta parte de la poblacion adulta femenina y mas de un tercio de la masculina presentaba HTG. Los factores independientes asociados con HTG fueron hipercolesterolemia y c-HDL bajo, y las variables cardiometabolicas diabetes, esteatosis hepatica y obesidad.

Published
2020
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3. Prevalence of hypertriglyceridemia in adults and related cardiometabolic factors. SIMETAP-HTG study

Author

Antonio, Ruiz-García, Ezequiel, Arranz-Martínez, Beatriz, López-Uriarte, Montserrat, Rivera-Teijido, David, Palacios-Martínez, Gema M, Dávila-Blázquez, Antonio, Rosillo-González, José Antonio, González-Posada Delgado, José Enrique, Mariño-Suárez, Enrique, Revilla-Pascual, José Luis, Quintana-Gómez, Ignacio, Íscar-Valenzuela, Rafael, Alonso-Roca, Ana Pilar, Javierre-Miranda, Rosa Ana, Escrivá-Ferrairó, Isabel, Tello-Meco, Ana María, Ibarra-Sánchez, M Isabel, Gutiérrez Sánchez, Juan Ramón, Iglesias Quintana, M Inmaculada, Hernández-Beltrán, Montserrat, Pérez Fernández, Elena, Barrios-Rueda, Raúl, Pérez Muñoz, Miguel, Prieto Marcos, Santiago, Delgado Rodríguez, Raquel, Pleite Raposo, Rafael, Rodríguez-Cabanillas, M Rosario, Morales-Chico, Diana, Fernández-Pacheco Vila, Beatriz, Remón-Pérez, M Jesús, Del Villar Redondo, Joaquina, Reguillo-Díaz, Paloma, Aguilera Reija, Ana Olga, Rodríguez Rodríguez, Ofelia, Gómez-Fernández, M Del Carmen, Antón-Sanz, Antonio, Sánchez-Calso, Norma Alejandra, Doria-Carlin, and Manuel J, Frías-Vargas

Subjects
Adult, Hypertriglyceridemia, Male, Analysis of Variance, Arteriosclerosis, Hypercholesterolemia, Fatty Liver, Age Distribution, Cross-Sectional Studies, Metabolic Diseases, Diabetes Mellitus, Prevalence, Humans, Female, Obesity, Renal Insufficiency, Chronic, Sex Distribution, Triglycerides
Abstract

To determine in the adult population the crude and the sex- and age-adjusted prevalence rates of hypertriglyceridaemia (HTG) and to assess its association with cardiovascular risk factors, chronic kidney disease, cardiovascular and cardiometabolic diseases.Cross-sectional observational study conducted in Primary Care, with 6,588 adult study subjects, randomly selected on base-population. Patients had HTG if the triglyceride level was≥150mg/dL (≥1.7mmol/L), or were on lipid-lowering therapy to lower triglyceride. Associations were assessed by univariate and multivariate analysis, and crude and sex- and age-adjusted prevalence rates were determined.The arithmetic and geometric means of triglyceride levels were respectively 120.5 and 104.2mg/dL in global population, 135.7 and 116.0mg/dL in men, and 108.6 and 95.7mg/dL in women. The crude HTG prevalence rates were 29.6% in global population, 36.9% in men and 23.8% in women. The sex- and age-adjusted HTG prevalence rates were 27.0% in global population, 34.6% in men and 21.4% in women. The independent variables that were most associated with HTG were hypercholesterolemia (OR: 4.6), low HDL-C (OR: 4.1), hepatic steatosis (OR: 2.8), diabetes (OR: 2.0), and obesity (OR: 1.9).The means of triglyceride levels and HTG prevalence rates are intermediate between those of other national and international studies. A fifth of the female adult population and more than a third of the male population had HTG. The independent factors associated with HTG were hypercholesterolemia and low HDL-C, and the cardiometabolic variables diabetes, hepatic steatosis and obesity.

Published
2020

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