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43 results on '"Rajandream, M.-A."'

1. The genome of the social amoeba Dictyostelium discoideum

Author

Eichinger, L., Pachebat, J. A., Glöckner, G., Rajandream, M.-A., Sucgang, R., Berriman, M., Song, J., Olsen, R., Szafranski, K., Xu, Q., Tunggal, B., Kummerfeld, S., Madera, M., Konfortov, B. A., Rivero, F., Bankier, A. T., Lehmann, R., Hamlin, N., Davies, R., Gaudet, P., Fey, P., Pilcher, K., Chen, G., Saunders, D., Sodergren, E., Davis, P., Kerhornou, A., Nie, X., Hall, N., Anjard, C., Hemphill, L., Bason, N., Farbrother, P., Desany, B., Just, E., Morio, T., Rost, R., Churcher, C., Cooper, J., Haydock, S., van Driessche, N., Cronin, A., Goodhead, I., Muzny, D., Mourier, T., Pain, A., Lu, M., Harper, D., Lindsay, R., Hauser, H., James, K., Quiles, M., Madan Babu, M., Saito, T., Buchrieser, C., Wardroper, A., Felder, M., Thangavelu, M., Johnson, D., Knights, A., Loulseged, H., Mungall, K., Oliver, K., Price, C., Quail, M. A., Urushihara, H., Hernandez, J., Rabbinowitsch, E., Steffen, D., Sanders, M., Ma, J., Kohara, Y., Sharp, S., Simmonds, M., Spiegler, S., Tivey, A., Sugano, S., White, B., Walker, D., Woodward, J., Winckler, T., Tanaka, Y., Shaulsky, G., Schleicher, M., Weinstock, G., Rosenthal, A., Cox, E. C., Chisholm, R. L., Gibbs, R., Loomis, W. F., Platzer, M., Kay, R. R., Williams, J., Dear, P. H., Noegel, A. A., Barrell, B., and Kuspa, A.

Published
2005
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2. Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13

Author

Hall, N., Pain, A., Berriman, M., Churcher, C., Harris, B., Harris, D., Mungall, K., Bowman, S., Atkin, R., Baker, S., Barron, A., Brooks, K., Buckee, C. O., Burrows, C., Cherevach, I., Chillingworth, C., Chillingworth, T., Christodoulou, Z., Clark, L., Clark, R., Corton, C., Cronin, A., Davies, R., Davis, P., Dear, P., Dearden, F., Doggett, J., Feltwell, T., Goble, A., Goodhead, I., Gwilliam, R., Hamlin, N., Hance, Z., Harper, D., Hauser, H., Hornsby, T., Holroyd, S., Horrocks, P., Humphray, S., Jagels, K., James, K. D., Johnson, D., Kerhornou, A., Knights, A., Konfortov, B., Kyes, S., Larke, N., Lawson, D., Lennard, N., Line, A., Maddison, M., McLean, J., Mooney, P., Moule, S., Murphy, L., Oliver, K., Ormond, D., Price, C., Quail, M. A., Rabbinowitsch, E., Rajandream, M.-A., Rutter, S., Rutherford, K. M., Sanders, M., Simmonds, M., Seeger, K., Sharp, S., Smith, R., Squares, R., Squares, S., Stevens, K., Taylor, K., Tivey, A., Unwin, L., Whitehead, S., Woodward, J., Sulston, J. E., Craig, A., Newbold, C., and Barrell, B. G.

Subjects
Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

Author(s): N. Hall (corresponding author) [1]; A. Pain [1]; M. Berriman [1]; C. Churcher [1]; B. Harris [1]; D. Harris [1]; K. Mungall [1]; S. Bowman [1, 2]; R. Atkin [...]

Published
2002
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3. Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)

Author

Bentley, S. D., Chater, K. F., Cerdeno-Tarraga, A.-M., Challis, G. L., Thomson, N. R., James, K. D., Harris, D. E., Quail, M. A., Kieser, H., Harper, D., Bateman, A., Brown, S., Chandra, G., Chen, C. W., Collins, M., Cronin, A., Fraser, A., Goble, A., Hidalgo, J., Hornsby, T., Howarth, S., Huang, C.-H., Kieser, T., Larke, L., Murphy, L., Oliver, K., O'Neil, S., Rabbinowitsch, E., Rajandream, M.-A., Rutherford, K., Rutter, S., Seeger, K., Saunders, D., Sharp, S., Squares, R., Squares, S., Taylor, K., Warren, T., Wietzorrek, A., Woodward, J., Barrell, B. G., Parkhill, J., and Hopwood, D. A.

Subjects
Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

Author(s): S. D. Bentley (corresponding author) [1]; K. F. Chater [2]; A.-M. Cerdeño-Tárraga [1]; G. L. Challis [2, 3]; N. R. Thomson [1]; K. D. James [1]; D. E. Harris [...]

Published
2002
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4. The genome sequence of Schizosaccharomyces pombe

Author

Wood, V., Gwilliam, R., Rajandream, M.-A., Lyne, M., Lyne, R., Stewart, A., Sgouros, J., Peat, N., Hayles, J., Baker, S., Basham, D., Bowman, S., Brooks, K., Brown, D., Brown, S., Chillingworth, T., Churcher, C., Collins, M., Connor, R., Cronin, A., Davis, P., Feltwell, T., Fraser, A., Gentles, S., Goble, A., Hamlin, N., Harris, D., Hidalgo, J., Hodgson, G., Holroyd, S., Hornsby, T., Howarth, S., Huckle, E. J., Hunt, S., Jagels, K., James, K., Jones, L., Jones, M., Leather, S., McDonald, S., McLean, J., Mooney, P., Moule, S., Mungall, K., Murphy, L., Niblett, D., Odell, C., Oliver, K., O'Neil, S., Pearson, D., Quail, M. A., Rabbinowitsch, E., Rutherford, K., Rutter, S., Saunders, D., Seeger, K., Sharp, S., Skelton, J., Simmonds, M., Squares, R., Squares, S., Stevens, K., Taylor, K., Taylor, R. G., Tivey, A., Walsh, S., Warren, T., Whitehead, S., Woodward, J., Volckaert, G., Aert, R., Robben, J., Grymonprez, B., Weltjens, I., Vanstreels, E., Rieger, M., Schafer, M., Muller-Auer, S., Gabel, C., Fuchs, M., Fritzc, C., Holzer, E., Moestl, D., Hilbert, H., Borzym, K., Langer, I., Beck, A., Lehrach, H., Reinhardt, R., Pohl, T. M., Eger, P., Zimmermann, W., Wedler, H., Wambutt, R., Purnelle, B., Goffeau, A., Cadieu, E., Dreano, S., Gloux, S., Lelaure, V., Mottier, S., Galibert, F., Aves, S. J., Xiang, Z., Hunt, C., Moore, K., Hurst, S. M., Lucas, M., Rochet, M., Gaillardin, C., Tallada, V. A., Garzon, A., Thode, G., Daga, R. R., Cruzado, L., Jimenez, J., Sanchez, M., del Rey, F., Benito, J., Dominguez, A., Revuelta, J. L., Moreno, S., Armstrong, J., Forsburg, S. L., Cerrutti, L., Lowe, T., McCombie, W. R., Paulsen, I., Potashkin, J., Shpakovski, G. V., Ussery, D., Barrell, B. G., and Nurse, P.

Subjects
Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

Author(s): V. Wood [1]; R. Gwilliam [1]; M.-A. Rajandream (corresponding author) [1]; M. Lyne [1]; R. Lyne [1]; A. Stewart [2]; J. Sgouros [2]; N. Peat [3]; J. Hayles [3]; [...]

Published
2002
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5. Massive gene decay in the leprosy bacillus

Author

Cole, S. T., Eiglmeier, K., Parkhill, J., James, K. D., Thomson, N. R., Wheeler, P. R., Honore, N., Garnier, T., Churcher, C., Harris, D., Mungall, K., Basham, D., Brown, D., Chillingworth, T., Connor, R., Davies, R. M., Devlin, K., Duthoy, S., Feltwell, T., Fraser, A., Hamlin, N., Holroyd, S., Hornsby, T., Jagels, K., Lacroix, C., Maclean, J., Moule, S., Murphy, L., Oliver, K., Quail, M. A., Rajandream, M.-A., Rutherford, K. M., Rutter, S., Seeger, K., Simon, S., Simmonds, M., Skelton, J., Squares, R., Squares, S., Stevens, K., Taylor, K., Whitehead, S., Woodward, J. R., and Barrell, B. G.

Subjects
Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

Author(s): S. T. Cole [1]; K. Eiglmeier [1]; J. Parkhill [2]; K. D. James [2]; N. R. Thomson [2]; P. R. Wheeler [3]; N. Honoré [1]; T. Garnier [1]; C. [...]

Published
2001
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6. Complete DNA sequence of a serogroup A strain of Neisseria meningitidis Z2491

Author

Parkhill, J., Achtman, M., James, K. D., Bentley, S. D., Churcher, C., Klee, S. R., Morelli, G., Basham, D., Brown, D., Chillingworth, T., Davies, R. M., Davis, P., Devlin, K., Feltwell, T., Hamlin, N., Holroyd, S., Jagels, K., Leather, S., Moule, S., Mungall, K., Quail, M. A., Rajandream, M.-A., Rutherford, K. M., Simmonds, M., Skelton, J., Whitehead, S., Spratt, B. G., and Barrell, B. G.

Subjects
Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

Author(s): J. Parkhill (corresponding author) [1]; M. Achtman [2]; K. D. James [1]; S. D. Bentley [1]; C. Churcher [1]; S. R. Klee [2]; G. Morelli [2]; D. Basham [1]; [...]

Published
2000
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7. The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences

Author

Parkhill, J., Wren, B. W., Mungall, K., Ketley, J. M., Churcher, C., Basham, D., Chillingworth, T., Davies, R. M., Feltwell, T., Holroyd, S., Jagels, K., Karlyshev, A. V., Moule, S., Pallen, M. J., Penn, C. W., Quail, M. A., Rajandream, M-A., Rutherford, K. M., van Vliet, A. H. M., Whitehead, S., and Barrell, B. G.

Subjects
Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

Author(s): J. Parkhill (corresponding author) [1]; B. W. Wren [2]; K. Mungall [1]; J. M. Ketley [3]; C. Churcher [1]; D. Basham [1]; T. Chillingworth [1]; R. M. Davies [1]; [...]

Published
2000
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8. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

Author

Cole, S. T., Brosch, R., Parkhill, J., Garnier, T., Churcher, C., Harris, D., Gordon, S. V., Eiglmeier, K., Gas, S., Barry, III, C. E., Tekaia, F., Badcock, K., Basham, D., Brown, D., Chillingworth, T., Connor, R., Davies, R., Devlin, K., Feltwell, T., Gentles, S., Hamlin, N., Holroyd, S., Hornsby, T., Jagels, K., Krogh, A., McLean, J., Moule, S., Murphy, L., Oliver, K., Osborne, J., Quail, M. A., Rajandream, M.-A., Rogers, J., Rutter, S., Seeger, K., Skelton, J., Squares, R., Squares, S., Sulston, J. E., Taylor, K., Whitehead, S., and Barrell, B. G.

Published
1998
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9. The genome of the simian and human malaria parasite Plasmodium knowlesi

Author

Pain, A., Böhme, U., Berry, A. E., Mungall, K., Finn, R. D., Jackson, A. P., Mourier, T., Mistry, J., Pasini, E. M., Aslett, M. A., Balasubrammaniam, S., Borgwardt, K., Brooks, K., Carret, C., Carver, T. J., Cherevach, I., Chillingworth, T., Clark, T. G., Galinski, M. R., Hall, N., Harper, D., Harris, D., Hauser, H., Ivens, A., Janssen, C. S., Keane, T., Larke, N., Lapp, S., Marti, M., Moule, S., Meyer, I. M., Ormond, D., Peters, N., Sanders, M., Sanders, S., Sargeant, T. J., Simmonds, M., Smith, F., Squares, R., Thurston, S., Tivey, A. R., Walker, D., White, B., Zuiderwijk, E., Churcher, C., Quail, M. A., Cowman, A. F., Turner, C. M. R., Rajandream, M. A., Kocken, C. H. M., Thomas, A. W., Newbold, C. I., Barrell, B. G., and Berriman, M.

Published
2008
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10. The complete nucleotide sequence of chromosome 3 of Plasmodium falciparum

Author

Bowman, S., Lawson, D., Basham, D., Brown, D., Chillingworth, T., Churcher, C. M., Craig, A., Davies, R. M., Devlin, K., Feltwell, T., Gentles, S., Gwilliam, R., Hamlin, N., Harris, D., Holroyd, S., Hornsby, T., Horrocks, P., Jagels, K., Jassal, B., Kyes, S., McLean, J., Moule, S., Mungall, K., Murphy, L., Oliver, K., Quail, M. A., Rajandream, M.-A., Rutter, S., Skelton, J., Squares, R., Squares, S., Sulston, J. E., Whitehead, S., Woodward, J. R., Newbold, C., and Barrell, B. G.

Published
1999

11. Progress in Arabidopsis genome sequencing and functional genomics

Author

Wambutt, R, Murphy, G, Volckaert, G, Pohl, T, Düsterhöft, A, Stiekema, W, Entian, K.-D, Terryn, N, Harris, B, Ansorge, W, Brandt, P, Grivell, L, Rieger, M, Weichselgartner, M, de Simone, V, Obermaier, B, Mache, R, Müller, M, Kreis, M, Delseny, M, Puigdomenech, P, Watson, M, Schmidtheini, T, Reichert, B, Portatelle, D, Perez-Alonso, M, Boutry, M, Bancroft, I, Vos, P, Hoheisel, J, Zimmermann, W, Wedler, H, Ridley, P, Langham, S.-A, McCullagh, B, Bilham, L, Robben, J, Van der Schueren, J, Grymonprez, B, Chuang, Y.-J, Vandenbussche, F, Braeken, M, Weltjens, I, Voet, M, Bastiaens, I, Aert, R, Defoor, E, Weitzenegger, T, Bothe, G, Ramsperger, U, Hilbert, H, Braun, M, Holzer, E, Brandt, A, Peters, S, van Staveren, M, Dirkse, W, Mooijman, P, Klein Lankhorst, R, Rose, M, Hauf, J, Kötter, P, Berneiser, S, Hempel, S, Feldpausch, M, Lamberth, S, Van den Daele, H, De Keyser, A, Buysshaert, C, Gielen, J, Villarroel, R, De Clercq, R, Van Montagu, M, Rogers, J, Cronin, A, Quail, M, Bray-Allen, S, Clark, L, Doggett, J, Hall, S, Kay, M, Lennard, N, McLay, K, Mayes, R, Pettett, A, Rajandream, M.-A, Lyne, M, Benes, V, Rechmann, S, Borkova, D, Blöcker, H, Scharfe, M, Grimm, M, Löhnert, T.-H, Dose, S, de Haan, M, Maarse, A, Schäfer, M, Müller-Auer, S, Gabel, C, Fuchs, M, Fartmann, B, Granderath, K, Dauner, D, Herzl, A, Neumann, S, Argiriou, A, Vitale, D, Liguori, R, Piravandi, E, Massenet, O, Quigley, F, Clabauld, G, Mündlein, A, Felber, R, Schnabl, S, Hiller, R, Schmidt, W, Lecharny, A, Aubourg, S, Gy, I, Cooke, R, Berger, C, Monfort, A, Casacuberta, E, Gibbons, T, Weber, N, Vandenbol, M, Bargues, M, Terol, J, Torres, A, Perez-Perez, A, Purnelle, B, Bent, E, Johnson, S, Tacon, D, Jesse, T, Heijnen, L, Schwarz, S, Scholler, P, Heber, S, Bielke, C, Frishmann, D, Haase, D, Lemcke, K, Mewes, H.W, Stocker, S, Zaccaria, P, Mayer, K, Schüller, C, and Bevan, M

Published
2000
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12. The genome sequence of Schizosaccharomyces pombe (vol 415, pg 871, 2002)

Author

Wood, V, Gwilliam, R, Rajandream, M, Lyne, M, Lyne, R, Stewart, A, Sgouros, J, Peat, N, Hayles, J, Baker, S, Basham, D, Bowman, S, Brooks, K, Brown, D, Brown, S, Chillingworth, T, Churcher, C, Collins, M, Connor, R, Cronin, A, Davis, P, Feltwell, T, Fraser, A, Gentles, S, and Goble, A

Published
2016

13. The Yeast Genome Directory

Author

Goffeau, A., Aert, R., Agostini-Carbone, M. L., Ahmed, A., Aigle, M., Alberghina, L., Albermann, K., Albers, M., Aldea, M., Alexandraki, D., Aljinovic, G., Allen, E., Alt-Mörbe, J., André, B., Andrews, S., Ansorge, W., Antoine, G., Anwar, R., Aparicio, A., Araujo, R., Arino, J., Arnold, F., Arroyo, J., Aviles, E., Backes, U., Baclet, M. C., Badcock, K., Bahr, A., Baladron, V., Ballesta, J. P. G., Bankier, A. T., Banrevi, A., Bargues, M., Baron, L., Barreiros, T., Barrell, B. G., Barthe, C., Barton, A. B., Baur, A., Bécam, A.-M., Becker, A., Becker, I., Beinhauer, J., Benes, V., Benit, P., Berben, G., Bergantino, E., Bergez, P., Berno, A., Bertani, I., Biteau, N., Bjourson, A. J., Blöcker, H., Blugeon, C., Bohn, C., Boles, E., Bolle, P. A., Bolotin-Fukuhara, M., Bordonné, R., Boskovic, J., Bossier, P., Botstein, D., Bou, G., Bowman, S., Boyer, J., Brandt, P., Brandt, T., Brendel, M., Brennan, T., Brinkman, R., Brown, A., Brown, A. J. P., Brown, D., Brückner, M., Bruschi, C. V., Buhler, J. M., Buitrago, M. J., Bussereau, F., Bussey, H., Camasses, A., Carcano, C., Carignani, G., Carpenter, J., Casamayor, A., Casas, C., Castagnoli, L., Cederberg, H., Cerdan, E., Chalwatzis, N., Chanet, R., Chen, E., Chéret, G., Cherry, J. M., Chillingworth, T., Christiansen, C., Chuat, J.-C., Chung, E., Churcher, C., Churcher, C. M., Clark, M. W., Clemente, M. L., Coblenz, A., Coglievina, M., Coissac, E., Colleaux, L., Connor, R., Contreras, R., Cooper, J., Copsey, T., Coster, F., Coster, R., Couch, J., Crouzet, M., Cziepluch, C., Daignan-Fornier, B., Dal Paro, F., Dang, D. V., D’Angelo, M., Davies, C. J., Davis, K., Davis, R. W., De Antoni, A., Dear, S., Dedman, K., Defoor, E., De Haan, M., Delaveau, Th., Del Bino, S., Delgado, M., Delius, H., Delneri, D., Del Rey, F., Demolder, J., Démolis, N., Devlin, K., de Wergifosse, P., Dietrich, F. S., Ding, H., Dion, C., Dipaolo, T., Doignon, F., Doira, C., Domdey, H., Dover, J., Du, Z., Dubois, E., Dujon, B., Duncan, M., Durand, P., Düsterhöft, A., Düsterhus, S., Eki, T., El Bakkoury, M., Eide, L. G., Entian, K.-D., Eraso, P., Erdmann, D., Erfle, H., Escribano, V., Esteban, M., Fabiani, L., Fabre, F., Fairhead, C., Fartmann, B., Favello, A., Faye, G., Feldmann, H., Fernandes, L., Feroli, F., Feuermann, M., Fiedler, T., Fiers, W., Fleig, U. N., Flöth, M., Fobo, G. M., Fortin, N., Foury, F., Francingues-Gaillard, M. C., Franco, L., Fraser, A., Friesen, J.D., Fritz, C., Frontali, L., Fukuhara, H., Fulton, L., Fuller, L. J., Gabel, C., Gaillardin, C., Gaillon, L., Galibert, F., Galisson, F., Galland, P., Gamo, F.-J., Gancedo, C., Garcia-Cantalejo, J. M., García-Gonzalez, M. I., Garcia-Ramirez, J. J., García-Saéz, M., Gassenhuber, H., Gatius, M., Gattung, S., Geisel, C., Gent, M. E., Gentles, S., Ghazvini, M., Gigot, D., Gilliquet, V., Glansdorff, N., Gómez-Peris, A., Gonzaléz, A., Goulding, S. E., Granotier, C., Greco, T., Grenson, M., Grisanti, P., Grivell, L. A., Grothues, D., Gueldener, U., Guerreiro, P., Guzman, E., Haasemann, M., Habbig, B., Hagiwara, H., Hall, J., Hallsworth, K., Hamlin, N., Hand, N. J., Hanemann, V., Hani, J., Hankeln, T., Hansen, M., Harris, D., Harris, D. E., Hartzell, G., Hatat, D., Hattenhorst, U., Hawkins, J., Hebling, U., Hegemann, J., Hein, C., Hennemann, A., Hennessy, K., Herbert, C. J., Hernandez, K., Hernando, Y., Herrero, E., Heumann, K., Heuss- Neitzel, D., Hewitt, N., Hiesel, R., Hilbert, H., Hilger, F., Hillier, L., Ho, C., Hoenicka, J., Hofmann, B., Hoheisel, J., Hohmann, S., Hollenberg, C. P., Holmstrøm, K., Horaitis, O., Horsnell, T. S., Huang, M.-E., Hughes, B., Hunicke-Smith, S., Hunt, S., Hunt, S. E., Huse, K., Hyman, R. W., Iborra, F., Indge, K. J., Iraqui Houssaini, I., Isono, K., Jacq, C., Jacquet, M., Jacquier, A., Jagels, K., Jäger, W., James, C. M., Jauniaux, J. C., Jia, Y., Jier, M., Jimenez, A., Johnson, D., Johnston, L., Johnston, M., Jones, M., Jonniaux, J.-L., Kaback, D. B., Kallesøe, T., Kalman, S., Kalogeropoulos, A., Karpfinger-Hartl, L., Kashkari, D., Katsoulou, C., Kayser, A., Kelly, A., Keng, T., Keuchel, H., Kiesau, P., Kirchrath, L., Kirsten, J., Kleine, K., Kleinhans, U., Klima, R., Komp, C., Kordes, E., Korol, S., Kötter, P., Krämer, C., Kramer, B., Kreisl, P., Kucaba, T., Kuester, H., Kurdi, O., Laamanen, P., Lafuente, M. J., Landt, O., Lanfranchi, G., Langston, Y., Lashkari, D., Latreille, P., Lauquin, G., Le, T., Legrain, P., Legros, Y., Lepingle, A., Lesveque, H., Leuther, H., Lew, H., Lewis, C., Li, Z. Y., Liebl, S., Lin, A., Lin, D., Logghe, M., Lohan, A. J. E., Louis, E. J., Lucchini, G., Lutzenkirchen, K., Lyck, R., Lye, G., Maarse, A. C., Maat, M. J., Macri, C., Madania, A., Maftahi, M., Maia e Silva, A., Maillier, E., Mallet, L., Mannhaupt, G., Manus, V., Marathe, R., Marck, C., Marconi, A., Mardis, E., Martegani, E., Martin, R., Mathieu, A., Maurer, C. T. C., Mazón, M. J., Mazzoni, C., McConnell, D., McDonald, S., McKee, R. A., McReynolds, A. D. K., Melchioretto, P., Menezes, S., Messenguy, F., Mewes, H. W., Michaux, G., Miller, N., Minenkova, O., Miosga, T., Mirtipati, S., Möller-Rieker, S., Möstl, D., Molemans, F., Monnet, A., Monnier, A-L., Montague, M. A., Moro, M., Mosedale, D., Möstl, D., Moule, S., Mouser, L., Murakami, Y., Müller-Auer, S., Mulligan, J., Murphy, L., Muzi Falconi, M., Naitou, M., Nakahara, K., Namath, A., Nasr, F., Navas, L., Nawrocki, A., Nelson, J., Nentwich, U., Netter, P., Neu, R., Newlon, C. S., Nhan, M., Nicaud, J.-M., Niedenthal, R. K., Nombela, C., Noone, D., Norgren, R., Nußbaumer, B., Obermaier, B., Odell, C., Öfner, P., Oh, C., Oliver, K., Oliver, S. G., Ouellette, B. F., Ozawa, M., Paces, V., Pallier, C., Pandolfo, D., Panzeri, L., Paoluzi, S., Parle-Mcdermott, A. G., Pascolo, S., Patricio, N., Pauley, A., Paulin, L., Pearson, B. M., Pearson, D., Peluso, D., Perea, J., Pérez-Alonso, M., Pérez-Ortin, J. E., Perrin, A., Petel, F. X., Pettersson, B., Pfeiffer, F., Philippsen, P., Piérard, A., Piravandi, E., Planta, R. J., Plevani, P., Poch, O., Poetsch, B., Pohl, F. M., Pohl, T. M., Pöhlmann, R., Poirey, R., Portetelle, D., Portillo, F., Potier, S., Proft, M., Prydz, H., Pujol, A., Purnelle, B., Puzos, V., Rajandream, M. A., Ramezani Rad, M., Rasmussen, S. W., Raynal, A., Rechmann, S., Remacha, M., Revuelta, J. L., Rice, P., Richard, G-F., Richterich, P., Rieger, M., Rifken, L., Riles, L., Rinaldi, T., Rinke, M., Roberts, A. B., Roberts, D., Rodriguez, F., Rodriguez-Belmonte, E., Rodriguez-Pousada, C., Rodriguez-Torres, A. M., Rose, M., Rossau, R., Rowley, N., Rupp, T., Ruzzi, M., Saeger, W., Saiz, J. E., Saliola, M., Salom, D., Saluz, H. P., Sánchez-Perez, M., Santos, M. A., Sanz, E., Sanz, J. E., Saren, A.-M., Sartorello, F., Sasanuma, M., Sasanuma, S-I., Scarcez, T., Schaaf-Gerstenschläger, I., Schäfer, B., Schäfer, M., Scharfe, M., Scherens, B., Schroff, N., Sen-Gupta, M., Shibata, T., Schmidheini, T., Schmidt, E. R., Schneider, C., Scholler, P., Schramm, S., Schreer, A., Schröder, M., Schwager, C., Schwarz, S., Schwarzlose, C., Schweitzer, B., Schweizer, M., Sdicu, A-M., Sehl, P., Sensen, C., Sgouros, J. G., Shogren, T., Shore, L., Shu, Y., Skala, J., Skelton, J., Slonimski, P. P., Smit, P. H. M., Smith, V., Soares, H., Soeda, E., Soler-Mira, A., Sor, F., Soriano, N., Souciet, J. L., Soustelle, C., Spiegelberg, R., Stateva, L. I., Steensma, H. Y., Stegemann, J., Steiner, S., Stellyes, L., Sterky, F., Storms, R. K., St. Peter, H., Stucka, R., Taich, A., Talla, E., Tarassov, I., Tashiro, H., Taylor, P., Teodoru, C., Tettelin, H., Thierry, A., Thireos, G., Tobiasch, E., Tovan, D., Trevaskis, E., Tsuchiya, Y., Tzermia, M., Uhlen, M., Underwood, A., Unseld, M., Urbanus, J. H. M., Urrestarazu, A., Ushinsky, S., Valens, M., Valle, G., Van Broekhoven, A., Vandenbol, M., Van Der Aart, Q. J. M., Van Der Linden, C. G., Van Dyck, L., Vanoni, M., Van Vliet-Reedijk, J. C., Vassarotti, A., Vaudin, M., Vaughan, K., Verhasselt, P., Vetter, I., Vierendeels, F., Vignati, D., Vilela, C., Vissers, S., Vleck, C., Vo, D. T., Vo, D. H., Voet, M., Volckaert, G., Von Wettstein, D., Voss, H., Vreken, P., Wagner, G., Walsh, S. V., Wambutt, R., Wang, H., Wang, Y., Warmington, J. R., Waterston, R., Watson, M. D., Weber, N., Wedler, E., Wedler, H., Wei, Y., Whitehead, S., Wicksteed, B. L., Wiemann, S., Wilcox, L., Wilson, C., Wilson, R., Winant, A., Winnett, E., Winsor, B., Wipfli, P., Wölfl, S., Wohldman, P., Wolf, K., Wolfe, K. H., Wright, L. F., Wurst, H., Xu, G., Yamasaki, M., Yelton, M. A., Yokohama, K., Yoshikawa, A., Yuping, S., Zaccaria, P., Zagulski, M., Zimmermann, F. K., Zimmermann, J., Zimmermann, M., Zhong, W-W., Zollner, A., and Zumstein, E.

Published
1997
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14. The genome of the simian and human malaria parasite Plasmodium knowlesi

Author

Pain, A, Böhme, U, Berry, A E, Mungall, K, Finn, R D, Jackson, A P, Mourier, T, Mistry, J, Pasini, E M, Aslett, M A, Balasubrammaniam, S, Borgwardt, K, Brooks, K, Carret, C, Carver, T J, Cherevach, I, Chillingworth, T, Clark, T G, Galinski, M R, Hall, N, Harper, D, Harris, D, Hauser, H, Ivens, A, Janssen, C S, Keane, T, Larke, N, Lapp, S, Marti, M, Moule, S, Meyer, I M, Ormond, D, Peters, N, Sanders, M, Sanders, S, Sargeant, T J, Simmonds, M, Smith, F, Squares, R, Thurston, S, Tivey, A R, Walker, D, White, B, Zuiderwijk, E, Churcher, C, Quail, M A, Cowman, A F, Turner, C M R, Rajandream, M A, Kocken, C H M, Thomas, A W, Newbold, C I, Barrell, B G, Berriman, M, Pain, A, Böhme, U, Berry, A E, Mungall, K, Finn, R D, Jackson, A P, Mourier, T, Mistry, J, Pasini, E M, Aslett, M A, Balasubrammaniam, S, Borgwardt, K, Brooks, K, Carret, C, Carver, T J, Cherevach, I, Chillingworth, T, Clark, T G, Galinski, M R, Hall, N, Harper, D, Harris, D, Hauser, H, Ivens, A, Janssen, C S, Keane, T, Larke, N, Lapp, S, Marti, M, Moule, S, Meyer, I M, Ormond, D, Peters, N, Sanders, M, Sanders, S, Sargeant, T J, Simmonds, M, Smith, F, Squares, R, Thurston, S, Tivey, A R, Walker, D, White, B, Zuiderwijk, E, Churcher, C, Quail, M A, Cowman, A F, Turner, C M R, Rajandream, M A, Kocken, C H M, Thomas, A W, Newbold, C I, Barrell, B G, and Berriman, M

Abstract

Udgivelsesdato: 2008-Oct-9, Plasmodium knowlesi is an intracellular malaria parasite whose natural vertebrate host is Macaca fascicularis (the 'kra' monkey); however, it is now increasingly recognized as a significant cause of human malaria, particularly in southeast Asia. Plasmodium knowlesi was the first malaria parasite species in which antigenic variation was demonstrated, and it has a close phylogenetic relationship to Plasmodium vivax, the second most important species of human malaria parasite (reviewed in ref. 4). Despite their relatedness, there are important phenotypic differences between them, such as host blood cell preference, absence of a dormant liver stage or 'hypnozoite' in P. knowlesi, and length of the asexual cycle (reviewed in ref. 4). Here we present an analysis of the P. knowlesi (H strain, Pk1(A+) clone) nuclear genome sequence. This is the first monkey malaria parasite genome to be described, and it provides an opportunity for comparison with the recently completed P. vivax genome and other sequenced Plasmodium genomes. In contrast to other Plasmodium genomes, putative variant antigen families are dispersed throughout the genome and are associated with intrachromosomal telomere repeats. One of these families, the KIRs, contains sequences that collectively match over one-half of the host CD99 extracellular domain, which may represent an unusual form of molecular mimicry.

Published
2008

15. The genome of the social amoeba Dictyostelium discoideum.

Author

Eichinger, L, Pachebat, J A, Glöckner, G, Rajandream, M-A, Sucgang, R, Berriman, M, Song, J, Olsen, R, Szafranski, K, Xu, Q, Tunggal, B, Kummerfeld, S, Madera, M, Konfortov, B A, Rivero, F, Bankier, A T, Lehmann, R, Hamlin, N, Davies, R, Gaudet, P, Fey, P, Pilcher, K, Chen, G, Saunders, D, Sodergren, E, Davis, P, Kerhornou, A, Nie, X, Hall, N, Anjard, C, Hemphill, L, Bason, N, Farbrother, P, Desany, B, Just, E, Morio, T, Rost, R, Churcher, C, Cooper, J, Haydock, S, van Driessche, N, Cronin, A, Goodhead, I, Muzny, D, Mourier, T, Pain, A, Lu, M, Harper, D, Lindsay, R, Hauser, H, James, K, Quiles, M, Madan Babu, M, Saito, T, Buchrieser, C, Wardroper, A, Felder, M, Thangavelu, M, Johnson, D, Knights, A, Loulseged, H, Mungall, K, Oliver, K, Price, C, Quail, M A, Urushihara, H, Hernandez, J, Rabbinowitsch, E, Steffen, D, Sanders, M, Ma, J, Kohara, Y, Sharp, S, Simmonds, M, Spiegler, S, Tivey, A, Sugano, S, White, B, Walker, D, Woodward, J, Winckler, T, Tanaka, Y, Shaulsky, G, Schleicher, M, Weinstock, G, Rosenthal, A, Cox, E C, Chisholm, R L, Gibbs, R, Loomis, W F, Platzer, M, Kay, R R, Williams, J, Dear, P H, Noegel, A A, Barrell, B, Kuspa, A, Eichinger, L, Pachebat, J A, Glöckner, G, Rajandream, M-A, Sucgang, R, Berriman, M, Song, J, Olsen, R, Szafranski, K, Xu, Q, Tunggal, B, Kummerfeld, S, Madera, M, Konfortov, B A, Rivero, F, Bankier, A T, Lehmann, R, Hamlin, N, Davies, R, Gaudet, P, Fey, P, Pilcher, K, Chen, G, Saunders, D, Sodergren, E, Davis, P, Kerhornou, A, Nie, X, Hall, N, Anjard, C, Hemphill, L, Bason, N, Farbrother, P, Desany, B, Just, E, Morio, T, Rost, R, Churcher, C, Cooper, J, Haydock, S, van Driessche, N, Cronin, A, Goodhead, I, Muzny, D, Mourier, T, Pain, A, Lu, M, Harper, D, Lindsay, R, Hauser, H, James, K, Quiles, M, Madan Babu, M, Saito, T, Buchrieser, C, Wardroper, A, Felder, M, Thangavelu, M, Johnson, D, Knights, A, Loulseged, H, Mungall, K, Oliver, K, Price, C, Quail, M A, Urushihara, H, Hernandez, J, Rabbinowitsch, E, Steffen, D, Sanders, M, Ma, J, Kohara, Y, Sharp, S, Simmonds, M, Spiegler, S, Tivey, A, Sugano, S, White, B, Walker, D, Woodward, J, Winckler, T, Tanaka, Y, Shaulsky, G, Schleicher, M, Weinstock, G, Rosenthal, A, Cox, E C, Chisholm, R L, Gibbs, R, Loomis, W F, Platzer, M, Kay, R R, Williams, J, Dear, P H, Noegel, A A, Barrell, B, and Kuspa, A

Abstract

Udgivelsesdato: 2005-May-5, The social amoebae are exceptional in their ability to alternate between unicellular and multicellular forms. Here we describe the genome of the best-studied member of this group, Dictyostelium discoideum. The gene-dense chromosomes of this organism encode approximately 12,500 predicted proteins, a high proportion of which have long, repetitive amino acid tracts. There are many genes for polyketide synthases and ABC transporters, suggesting an extensive secondary metabolism for producing and exporting small molecules. The genome is rich in complex repeats, one class of which is clustered and may serve as centromeres. Partial copies of the extrachromosomal ribosomal DNA (rDNA) element are found at the ends of each chromosome, suggesting a novel telomere structure and the use of a common mechanism to maintain both the rDNA and chromosomal termini. A proteome-based phylogeny shows that the amoebozoa diverged from the animal-fungal lineage after the plant-animal split, but Dictyostelium seems to have retained more of the diversity of the ancestral genome than have plants, animals or fungi.

Published
2005

16. Characterization of a novel wood mouse virus related to murid herpesvirus 4

Author

Hughes, D. J., primary, Kipar, A., additional, Milligan, S. G., additional, Cunningham, C., additional, Sanders, M., additional, Quail, M. A., additional, Rajandream, M.-A., additional, Efstathiou, S., additional, Bowden, R. J., additional, Chastel, C., additional, Bennett, M., additional, Sample, J. T., additional, Barrell, B., additional, Davison, A. J., additional, and Stewart, J. P., additional

Published
2009
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17. Progress in Arabidopsis genome sequencing and functional genomics

Author

UCL - SST/ISV - Institut des sciences de la vie, Wambutt, R, Murphy, G, Volckaert, G, Pohl, T, Düsterhöft, A, Stiekema, W, Entian, K.-D, Terryn, N, Harris, B, Ansorge, W, Brandt, P, Grivell, L, Rieger, M, Weichselgartner, M, de Simone, V, Obermaier, B, Mache, R, Müller, M, Kreis, M, Delseny, M, Puigdomenech, P, Watson, M, Schmidtheini, T, Reichert, B, Portatelle, D, Perez-Alonso, M, Boutry, Marc, Bancroft, I, Vos, P, Hoheisel, J, Zimmermann, W, Wedler, H, Ridley, P, Langham, S.-A, McCullagh, B, Bilham, L, Robben, J, Van der Schueren, J, Grymonprez, B, Chuang, Y.-J, Vandenbussche, F, Braeken, M, Weltjens, I, Voet, M, Bastiaens, I, Aert, R, Defoor, E, Weitzenegger, T, Bothe, G, Ramsperger, U, Hilbert, H, Braun, M, Holzer, E, Brandt, A, Peters, S, van Staveren, M, Dirkse, W, Mooijman, P, Klein Lankhorst, R, Rose, M, Hauf, J, Kötter, P, Berneiser, S, Hempel, S, Feldpausch, M, Lamberth, S, Van den Daele, H, De Keyser, A, Buysshaert, C, Gielen, J, Villarroel, R, De Clercq, R, Van Montagu, M, Rogers, J, Cronin, A, Quail, M, Bray-Allen, S, Clark, L, Doggett, J, Hall, S, Kay, M, Lennard, N, McLay, K, Mayes, R, Pettett, A, Rajandream, M.-A, Lyne, M, Benes, V, Rechmann, S, Borkova, D, Blöcker, H, Scharfe, M, Grimm, M, Löhnert, T.-H, Dose, S, de Haan, M, Maarse, A, Schäfer, M, Müller-Auer, S, Gabel, C, Fuchs, M, Fartmann, B, Granderath, K, Dauner, D, Herzl, A, Neumann, S, Argiriou, A, Vitale, D, Liguori, R, Piravandi, E, Massenet, O, Quigley, F, Clabauld, G, Mündlein, A, Felber, R, Schnabl, S, Hiller, R, Schmidt, W, Lecharny, A, Aubourg, S, Gy, I, Cooke, R, Berger, C, Monfort, A, Casacuberta, E, Gibbons, T, Weber, N, Vandenbol, M, Bargues, M, Terol, J, Torres, A, Perez-Perez, A, Purnelle, B, Bent, E, Johnson, S, Tacon, D, Jesse, T, Heijnen, L, Schwarz, S, Scholler, P, Heber, S, Bielke, C, Frishmann, D, Haase, D, Lemcke, K, Mewes, H.W, Stocker, S, Zaccaria, P, Mayer, K, Schüller, C, Bevan, M, UCL - SST/ISV - Institut des sciences de la vie, Wambutt, R, Murphy, G, Volckaert, G, Pohl, T, Düsterhöft, A, Stiekema, W, Entian, K.-D, Terryn, N, Harris, B, Ansorge, W, Brandt, P, Grivell, L, Rieger, M, Weichselgartner, M, de Simone, V, Obermaier, B, Mache, R, Müller, M, Kreis, M, Delseny, M, Puigdomenech, P, Watson, M, Schmidtheini, T, Reichert, B, Portatelle, D, Perez-Alonso, M, Boutry, Marc, Bancroft, I, Vos, P, Hoheisel, J, Zimmermann, W, Wedler, H, Ridley, P, Langham, S.-A, McCullagh, B, Bilham, L, Robben, J, Van der Schueren, J, Grymonprez, B, Chuang, Y.-J, Vandenbussche, F, Braeken, M, Weltjens, I, Voet, M, Bastiaens, I, Aert, R, Defoor, E, Weitzenegger, T, Bothe, G, Ramsperger, U, Hilbert, H, Braun, M, Holzer, E, Brandt, A, Peters, S, van Staveren, M, Dirkse, W, Mooijman, P, Klein Lankhorst, R, Rose, M, Hauf, J, Kötter, P, Berneiser, S, Hempel, S, Feldpausch, M, Lamberth, S, Van den Daele, H, De Keyser, A, Buysshaert, C, Gielen, J, Villarroel, R, De Clercq, R, Van Montagu, M, Rogers, J, Cronin, A, Quail, M, Bray-Allen, S, Clark, L, Doggett, J, Hall, S, Kay, M, Lennard, N, McLay, K, Mayes, R, Pettett, A, Rajandream, M.-A, Lyne, M, Benes, V, Rechmann, S, Borkova, D, Blöcker, H, Scharfe, M, Grimm, M, Löhnert, T.-H, Dose, S, de Haan, M, Maarse, A, Schäfer, M, Müller-Auer, S, Gabel, C, Fuchs, M, Fartmann, B, Granderath, K, Dauner, D, Herzl, A, Neumann, S, Argiriou, A, Vitale, D, Liguori, R, Piravandi, E, Massenet, O, Quigley, F, Clabauld, G, Mündlein, A, Felber, R, Schnabl, S, Hiller, R, Schmidt, W, Lecharny, A, Aubourg, S, Gy, I, Cooke, R, Berger, C, Monfort, A, Casacuberta, E, Gibbons, T, Weber, N, Vandenbol, M, Bargues, M, Terol, J, Torres, A, Perez-Perez, A, Purnelle, B, Bent, E, Johnson, S, Tacon, D, Jesse, T, Heijnen, L, Schwarz, S, Scholler, P, Heber, S, Bielke, C, Frishmann, D, Haase, D, Lemcke, K, Mewes, H.W, Stocker, S, Zaccaria, P, Mayer, K, Schüller, C, and Bevan, M

Published
2000

18. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana

Author

UCL - SST/ISV - Institut des sciences de la vie, Mayer, K., Schüller, C., Wambutt, R., Murphy, G., Volckaert, G., Pohl, T., Düsterhöft, A., Stiekema, W., Entian, K.-D., Terryn, N., Harris, B., Ansorge, W., Brandt, P., Grivell, L., Rieger, M., Weichselgartner, M., de Simone, V., Obermaier, B., Mache, R., Müller, M., Kreis, M., Delseny, M., Puigdomenech, P., Watson, M., Schmidtheini, T., Reichert, B., Portatelle, D., Perez-Alonso, M., Boutry, Marc, Bancroft, I., Vos, P., Hoheisel, J., Zimmermann, W., Wedler, H., Ridley, P., Langham, S.-A., McCullagh, B., Bilham, L., Robben, J., Van der Schueren, J., Grymonprez, B., Chuang, Y.-J., Vandenbussche, F., Braeken, M., Weltjens, I., Voet, M., Bastiaens, I., Aert, R., Defoor, E., Weitzenegger, T., Bothe, G., Ramsperger, U., Hilbert, H., Braun, M., Holzer, E., Brandt, A., Peters, S., van Staveren, M., Dirkse, W., Mooijman, P., Lankhorst, R. Klein, Rose, M., Hauf, J., Kötter, P., Berneiser, S., Hempel, S., Feldpausch, M., Lamberth, S., Van den Daele, H., De Keyser, A., Buysshaert, C., Gielen, J., Villarroel, R., De Clercq, R., Van Montagu, M., Rogers, J., Cronin, A., Quail, M., Bray-Allen, S., Clark, L., Doggett, J., Hall, S., Kay, M., Lennard, N., McLay, K., Mayes, R., Pettett, A., Rajandream, M.-A., Lyne, M., Benes, V., Rechmann, S., Borkova, D., Blöcker, H., Scharfe, M., Grimm, M., Löhnert, T.-H., Dose, S., de Haan, M., Maarse, A., Schäfer, M., Müller-Auer, S., Gabel, C., Fuchs, M., Fartmann, B., Granderath, K., Dauner, D., Herzl, A., Neumann, S., Argiriou, A., Vitale, D., Liguori, R., Piravandi, E., Massenet, O., Quigley, F., Clabauld, G., Mündlein, A., Felber, R., Schnabl, S., Hiller, R., Schmidt, W., Lecharny, A., Aubourg, S., Chefdor, F., Cooke, R., Berger, C., Montfort, A., Casacuberta, E., Gibbons, T., Weber, N., Vandenbol, M., Bargues, M., Terol, J., Torres, A., Perez-Perez, A., Purnelle, B., Bent, E., Johnson, S., Tacon, D., Jesse, T., Heijnen, L., Schwarz, S., Scholler, P., Heber, S., Francs, P., Bielke, C., Frishman, D., Haase, D., Lemcke, K., Mewes, H. W., Stocker, S., Zaccaria, P., Wilson, R. K., de la Bastide, M., Habermann, K., Parnell, L., Dedhia, N., Gnoj, L., Schutz, K., Huang, E., Spiegel, L., Sehkon, M., Murray, J., Sheet, P., Cordes, M., Abu-Threideh, J., Stoneking, T., Kalicki, J., Graves, T., Harmon, G., Edwards, J., Latreille, P., Courtney, L., Cloud, J., Abbott, A., Scott, K., Johnson, D., Minx, P., Bentley, D., Fulton, B., Miller, N., Greco, T., Kemp, K., Kramer, J., Fulton, L., Mardis, E., Dante, M., Pepin, K., Hillier, L., Nelson, J., Spieth, J., Ryan, E., Andrews, S., Geisel, C., Layman, D., Du, H., Ali, J., Berghoff, A., Jones, K., Drone, K., Cotton, M., Joshu, C., Antonoiu, B., Zidanic, M., Strong, C., Sun, H., Lamar, B., Yordan, C., Ma, P., Zhong, J., Preston, R., Vil, D., Shekher, M., Matero, A., Shah, R., Swaby, I'K., O'Shaughnessy, A., Rodriguez, M., Hoffman, J., Till, S., Granat, S., Shohdy, N., Hasegawa, A., Hameed, A., Lodhi, M., Johnson, A., Chen, E., Marra, M., Martienssen, R., McCombie, W. R., UCL - SST/ISV - Institut des sciences de la vie, Mayer, K., Schüller, C., Wambutt, R., Murphy, G., Volckaert, G., Pohl, T., Düsterhöft, A., Stiekema, W., Entian, K.-D., Terryn, N., Harris, B., Ansorge, W., Brandt, P., Grivell, L., Rieger, M., Weichselgartner, M., de Simone, V., Obermaier, B., Mache, R., Müller, M., Kreis, M., Delseny, M., Puigdomenech, P., Watson, M., Schmidtheini, T., Reichert, B., Portatelle, D., Perez-Alonso, M., Boutry, Marc, Bancroft, I., Vos, P., Hoheisel, J., Zimmermann, W., Wedler, H., Ridley, P., Langham, S.-A., McCullagh, B., Bilham, L., Robben, J., Van der Schueren, J., Grymonprez, B., Chuang, Y.-J., Vandenbussche, F., Braeken, M., Weltjens, I., Voet, M., Bastiaens, I., Aert, R., Defoor, E., Weitzenegger, T., Bothe, G., Ramsperger, U., Hilbert, H., Braun, M., Holzer, E., Brandt, A., Peters, S., van Staveren, M., Dirkse, W., Mooijman, P., Lankhorst, R. Klein, Rose, M., Hauf, J., Kötter, P., Berneiser, S., Hempel, S., Feldpausch, M., Lamberth, S., Van den Daele, H., De Keyser, A., Buysshaert, C., Gielen, J., Villarroel, R., De Clercq, R., Van Montagu, M., Rogers, J., Cronin, A., Quail, M., Bray-Allen, S., Clark, L., Doggett, J., Hall, S., Kay, M., Lennard, N., McLay, K., Mayes, R., Pettett, A., Rajandream, M.-A., Lyne, M., Benes, V., Rechmann, S., Borkova, D., Blöcker, H., Scharfe, M., Grimm, M., Löhnert, T.-H., Dose, S., de Haan, M., Maarse, A., Schäfer, M., Müller-Auer, S., Gabel, C., Fuchs, M., Fartmann, B., Granderath, K., Dauner, D., Herzl, A., Neumann, S., Argiriou, A., Vitale, D., Liguori, R., Piravandi, E., Massenet, O., Quigley, F., Clabauld, G., Mündlein, A., Felber, R., Schnabl, S., Hiller, R., Schmidt, W., Lecharny, A., Aubourg, S., Chefdor, F., Cooke, R., Berger, C., Montfort, A., Casacuberta, E., Gibbons, T., Weber, N., Vandenbol, M., Bargues, M., Terol, J., Torres, A., Perez-Perez, A., Purnelle, B., Bent, E., Johnson, S., Tacon, D., Jesse, T., Heijnen, L., Schwarz, S., Scholler, P., Heber, S., Francs, P., Bielke, C., Frishman, D., Haase, D., Lemcke, K., Mewes, H. W., Stocker, S., Zaccaria, P., Wilson, R. K., de la Bastide, M., Habermann, K., Parnell, L., Dedhia, N., Gnoj, L., Schutz, K., Huang, E., Spiegel, L., Sehkon, M., Murray, J., Sheet, P., Cordes, M., Abu-Threideh, J., Stoneking, T., Kalicki, J., Graves, T., Harmon, G., Edwards, J., Latreille, P., Courtney, L., Cloud, J., Abbott, A., Scott, K., Johnson, D., Minx, P., Bentley, D., Fulton, B., Miller, N., Greco, T., Kemp, K., Kramer, J., Fulton, L., Mardis, E., Dante, M., Pepin, K., Hillier, L., Nelson, J., Spieth, J., Ryan, E., Andrews, S., Geisel, C., Layman, D., Du, H., Ali, J., Berghoff, A., Jones, K., Drone, K., Cotton, M., Joshu, C., Antonoiu, B., Zidanic, M., Strong, C., Sun, H., Lamar, B., Yordan, C., Ma, P., Zhong, J., Preston, R., Vil, D., Shekher, M., Matero, A., Shah, R., Swaby, I'K., O'Shaughnessy, A., Rodriguez, M., Hoffman, J., Till, S., Granat, S., Shohdy, N., Hasegawa, A., Hameed, A., Lodhi, M., Johnson, A., Chen, E., Marra, M., Martienssen, R., and McCombie, W. R.

Abstract

The higher plant Arabidopsis thaliana (Arabidopsis) is an important model for identifying plant genes and determining their function. To assist biological investigations and to define chromosome structure, a coordinated effort to sequence the Arabidopsis genome was initiated in late 1996. Here we report one of the first milestones of this project, the sequence of chromosome 4. Analysis of 17.38 megabases of unique sequence, representing about 17% of the genome, reveals 3,744 protein coding genes, 81 transfer RNAs and numerous repeat elements. Heterochromatic regions surrounding the putative centromere, which has not yet been completely sequenced, are characterized by an increased frequency of a variety of repeats, new repeats, reduced recombination, lowered gene density and lowered gene expression. Roughly 60% of the predicted protein-coding genes have been functionally characterized on the basis of their homology to known genes. Many genes encode predicted proteins that are homologous to human and Caenorhabditis elegans proteins.

Published
1999

19. ACT: the Artemis comparison tool

Author

Carver, T. J., primary, Rutherford, K. M., additional, Berriman, M., additional, Rajandream, M.-A., additional, Barrell, B. G., additional, and Parkhill, J., additional

Published
2005
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20. corrigendum: The genome sequence of Schizosaccharomyces pombe

Author

Wood, V., Gwilliam, R., Rajandream, M.-A., Lyne, M., Lyne, R., Stewart, A., Sgouros, J., Peat, N., Hayles, J., Baker, S., Basham, D., Bowman, S., Brooks, K., Brown, D., Brown, S., Chillingworth, T., Churcher, C., Collins, M., Connor, R., Cronin, A., Davis, P., Feltwell, T., Fraser, A., Gentles, S., Goble, A., Hamlin, N., Harris, D., Hidalgo, J., Hodgson, G., Holroyd, S., Hornsby, T., Howarth, S., Huckle, E. J., Hunt, S., Jagels, K., James, K., Jones, L., Jones, M., Leather, S., McDonald, S., McLean, J., Mooney, P., Moule, S., Mungall, K., Murphy, L., Niblett, D., Odell, C., Oliver, K., O'Neil, S., Pearson, D., Quail, M. A., Rabbinowitsch, E., Rutherford, K., Rutter, S., Saunders, D., Seeger, K., Sharp, S., Skelton, J., Simmonds, M., Squares, R., Squares, S., Stevens, K., Taylor, K., Taylor, R. G., Tivey, A., Walsh, S., Warren, T., Whitehead, S., Woodward, J., Volckaert, G., Aert, R., Robben, J., Grymonprez, B., Weltjens, I., Vanstreels, E., Rieger, M., Schafer, M., Muller-Auer, S., Gabel, C., Fuchs, M., Dusterhoft, A., Fritzc, C., Holzer, E., Moestl, D., Hilbert, H., Borzym, K., Langer, I., Beck, A., Lehrach, H., Reinhardt, R., Pohl, T. M., Eger, P., Zimmermann, W., Wedler, H., Wambutt, R., Purnelle, B., Goffeau, A., Cadieu, E., Dreano, S., Gloux, S., Lelaure, V., Mottier, S., Galibert, F., Aves, S. J., Xiang, Z., Hunt, C., Moore, K., Hurst, S. M., Lucas, M., Rochet, M., Gaillardin, C., Tallada, V. A., Garzon, A., Thode, G., Daga, R. R., Cruzado, L., Jimenez, J., Sanchez, M., del Rey, F., Benito, J., Dominguez, A., Revuelta, J. L., Moreno, S., Armstrong, J., Forsburg, S. L., Cerutti, L., Lowe, T., McCombie, W. R., Paulsen, I., Potashkin, J., Shpakovski, G. V., Ussery, D., Barrell, B. G., and Nurse, P.

Subjects
Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

Author(s): V. Wood; R. Gwilliam; M.-A. Rajandream; M. Lyne; R. Lyne; A. Stewart; J. Sgouros; N. Peat; J. Hayles; S. Baker; D. Basham; S. Bowman; K. Brooks; D. Brown; S. [...]

Published
2003
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21. Erratum: corrigendum: The genome sequence of Schizosaccharomyces pombe

Author

Wood, V., primary, Gwilliam, R., additional, Rajandream, M.-A., additional, Lyne, M., additional, Lyne, R., additional, Stewart, A., additional, Sgouros, J., additional, Peat, N., additional, Hayles, J., additional, Baker, S., additional, Basham, D., additional, Bowman, S., additional, Brooks, K., additional, Brown, D., additional, Brown, S., additional, Chillingworth, T., additional, Churcher, C., additional, Collins, M., additional, Connor, R., additional, Cronin, A., additional, Davis, P., additional, Feltwell, T., additional, Fraser, A., additional, Gentles, S., additional, Goble, A., additional, Hamlin, N., additional, Harris, D., additional, Hidalgo, J., additional, Hodgson, G., additional, Holroyd, S., additional, Hornsby, T., additional, Howarth, S., additional, Huckle, E. J., additional, Hunt, S., additional, Jagels, K., additional, James, K., additional, Jones, L., additional, Jones, M., additional, Leather, S., additional, McDonald, S., additional, McLean, J., additional, Mooney, P., additional, Moule, S., additional, Mungall, K., additional, Murphy, L., additional, Niblett, D., additional, Odell, C., additional, Oliver, K., additional, O'Neil, S., additional, Pearson, D., additional, Quail, M. A., additional, Rabbinowitsch, E., additional, Rutherford, K., additional, Rutter, S., additional, Saunders, D., additional, Seeger, K., additional, Sharp, S., additional, Skelton, J., additional, Simmonds, M., additional, Squares, R., additional, Squares, S., additional, Stevens, K., additional, Taylor, K., additional, Taylor, R. G., additional, Tivey, A., additional, Walsh, S., additional, Warren, T., additional, Whitehead, S., additional, Woodward, J., additional, Volckaert, G., additional, Aert, R., additional, Robben, J., additional, Grymonprez, B., additional, Weltjens, I., additional, Vanstreels, E., additional, Rieger, M., additional, Schäfer, M., additional, Müller-Auer, S., additional, Gabel, C., additional, Fuchs, M., additional, Düsterhöft, A., additional, Fritzc, C., additional, Holzer, E., additional, Moestl, D., additional, Hilbert, H., additional, Borzym, K., additional, Langer, I., additional, Beck, A., additional, Lehrach, H., additional, Reinhardt, R., additional, Pohl, T. M., additional, Eger, P., additional, Zimmermann, W., additional, Wedler, H., additional, Wambutt, R., additional, Purnelle, B., additional, Goffeau, A., additional, Cadieu, E., additional, Dréano, S., additional, Gloux, S., additional, Lelaure, V., additional, Mottier, S., additional, Galibert, F., additional, Aves, S. J., additional, Xiang, Z., additional, Hunt, C., additional, Moore, K., additional, Hurst, S. M., additional, Lucas, M., additional, Rochet, M., additional, Gaillardin, C., additional, Tallada, V. A., additional, Garzon, A., additional, Thode, G., additional, Daga, R. R., additional, Cruzado, L., additional, Jimenez, J., additional, Sánchez, M., additional, del Rey, F., additional, Benito, J., additional, Domínguez, A., additional, Revuelta, J. L., additional, Moreno, S., additional, Armstrong, J., additional, Forsburg, S. L., additional, Cerutti, L., additional, Lowe, T., additional, McCombie, W. R., additional, Paulsen, I., additional, Potashkin, J., additional, Shpakovski, G. V., additional, Ussery, D., additional, Barrell, B. G., additional, and Nurse, P., additional

Published
2003
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24. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana

Author

Mayer, K., primary, Schüller, C., additional, Wambutt, R., additional, Murphy, G., additional, Volckaert, G., additional, Pohl, T., additional, Düsterhöft, A., additional, Stiekema, W., additional, Entian, K.-D., additional, Terryn, N., additional, Harris, B., additional, Ansorge, W., additional, Brandt, P., additional, Grivell, L., additional, Rieger, M., additional, Weichselgartner, M., additional, de Simone, V., additional, Obermaier, B., additional, Mache, R., additional, Müller, M., additional, Kreis, M., additional, Delseny, M., additional, Puigdomenech, P., additional, Watson, M., additional, Schmidtheini, T., additional, Reichert, B., additional, Portatelle, D., additional, Perez-Alonso, M., additional, Boutry, M., additional, Bancroft, I., additional, Vos, P., additional, Hoheisel, J., additional, Zimmermann, W., additional, Wedler, H., additional, Ridley, P., additional, Langham, S.-A., additional, McCullagh, B., additional, Bilham, L., additional, Robben, J., additional, Van der Schueren, J., additional, Grymonprez, B., additional, Chuang, Y.-J., additional, Vandenbussche, F., additional, Braeken, M., additional, Weltjens, I., additional, Voet, M., additional, Bastiaens, I., additional, Aert, R., additional, Defoor, E., additional, Weitzenegger, T., additional, Bothe, G., additional, Ramsperger, U., additional, Hilbert, H., additional, Braun, M., additional, Holzer, E., additional, Brandt, A., additional, Peters, S., additional, van Staveren, M., additional, Dirkse, W., additional, Mooijman, P., additional, Lankhorst, R. Klein, additional, Rose, M., additional, Hauf, J., additional, Kötter, P., additional, Berneiser, S., additional, Hempel, S., additional, Feldpausch, M., additional, Lamberth, S., additional, Van den Daele, H., additional, De Keyser, A., additional, Buysshaert, C., additional, Gielen, J., additional, Villarroel, R., additional, De Clercq, R., additional, Van Montagu, M., additional, Rogers, J., additional, Cronin, A., additional, Quail, M., additional, Bray-Allen, S., additional, Clark, L., additional, Doggett, J., additional, Hall, S., additional, Kay, M., additional, Lennard, N., additional, McLay, K., additional, Mayes, R., additional, Pettett, A., additional, Rajandream, M.-A., additional, Lyne, M., additional, Benes, V., additional, Rechmann, S., additional, Borkova, D., additional, Blöcker, H., additional, Scharfe, M., additional, Grimm, M., additional, Löhnert, T.-H., additional, Dose, S., additional, de Haan, M., additional, Maarse, A., additional, Schäfer, M., additional, Müller-Auer, S., additional, Gabel, C., additional, Fuchs, M., additional, Fartmann, B., additional, Granderath, K., additional, Dauner, D., additional, Herzl, A., additional, Neumann, S., additional, Argiriou, A., additional, Vitale, D., additional, Liguori, R., additional, Piravandi, E., additional, Massenet, O., additional, Quigley, F., additional, Clabauld, G., additional, Mündlein, A., additional, Felber, R., additional, Schnabl, S., additional, Hiller, R., additional, Schmidt, W., additional, Lecharny, A., additional, Aubourg, S., additional, Chefdor, F., additional, Cooke, R., additional, Berger, C., additional, Montfort, A., additional, Casacuberta, E., additional, Gibbons, T., additional, Weber, N., additional, Vandenbol, M., additional, Bargues, M., additional, Terol, J., additional, Torres, A., additional, Perez-Perez, A., additional, Purnelle, B., additional, Bent, E., additional, Johnson, S., additional, Tacon, D., additional, Jesse, T., additional, Heijnen, L., additional, Schwarz, S., additional, Scholler, P., additional, Heber, S., additional, Francs, P., additional, Bielke, C., additional, Frishman, D., additional, Haase, D., additional, Lemcke, K., additional, Mewes, H. W., additional, Stocker, S., additional, Zaccaria, P., additional, Bevan, M., additional, Wilson, R. K., additional, de la Bastide, M., additional, Habermann, K., additional, Parnell, L., additional, Dedhia, N., additional, Gnoj, L., additional, Schutz, K., additional, Huang, E., additional, Spiegel, L., additional, Sehkon, M., additional, Murray, J., additional, Sheet, P., additional, Cordes, M., additional, Abu-Threideh, J., additional, Stoneking, T., additional, Kalicki, J., additional, Graves, T., additional, Harmon, G., additional, Edwards, J., additional, Latreille, P., additional, Courtney, L., additional, Cloud, J., additional, Abbott, A., additional, Scott, K., additional, Johnson, D., additional, Minx, P., additional, Bentley, D., additional, Fulton, B., additional, Miller, N., additional, Greco, T., additional, Kemp, K., additional, Kramer, J., additional, Fulton, L., additional, Mardis, E., additional, Dante, M., additional, Pepin, K., additional, Hillier, L., additional, Nelson, J., additional, Spieth, J., additional, Ryan, E., additional, Andrews, S., additional, Geisel, C., additional, Layman, D., additional, Du, H., additional, Ali, J., additional, Berghoff, A., additional, Jones, K., additional, Drone, K., additional, Cotton, M., additional, Joshu, C., additional, Antonoiu, B., additional, Zidanic, M., additional, Strong, C., additional, Sun, H., additional, Lamar, B., additional, Yordan, C., additional, Ma, P., additional, Zhong, J., additional, Preston, R., additional, Vil, D., additional, Shekher, M., additional, Matero, A., additional, Shah, R., additional, Swaby, I'K., additional, O'Shaughnessy, A., additional, Rodriguez, M., additional, Hoffman, J., additional, Till, S., additional, Granat, S., additional, Shohdy, N., additional, Hasegawa, A., additional, Hameed, A., additional, Lodhi, M., additional, Johnson, A., additional, Chen, E., additional, Marra, M., additional, Martienssen, R., additional, and McCombie, W. R., additional

Published
1999
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25. The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII

Author

Bowman, S., primary, Churcher, C., additional, Badcock, K., additional, Brown, D., additional, Chillingworth, T., additional, Connor, R., additional, Dedman, K, additional, Devlin, K., additional, Gentles, S., additional, Hamlin, N., additional, Hunt,, S., additional, Jagels, K., additional, Lye, G., additional, Moule, S., additional, Odell, C., additional, Pearson, D., additional, Rajandream, M., additional, Rice, P., additional, Skelton, J., additional, Walsh, S., additional, Whitehead, S., additional, and Barrell, B., additional

Published
1997
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26. The nucleotide sequence of Saccharomyces cerevisiae chromosome IX

Author

Churcher, C., primary, Bowman, S., additional, Badcock, K., additional, Bankier, A., additional, Brown, D., additional, Chillingworth, T., additional, Connor, R., additional, Devlin, K., additional, Gentles, S., additional, Hamlin, N., additional, Harris, D., additional, Horsnell, T., additional, Hunt, S., additional, Jagels, K., additional, Jones, M., additional, Lye, G., additional, Moule, S., additional, Odell, C., additional, Pearson, D., additional, Rajandream, M., additional, Rice, P., additional, Rowley, N., additional, Skelton, J., additional, Smith, V., additional, Walsh, S., additional, Whitehead, S., additional, and Barrell, B., additional

Published
1997
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29. Sequence analysis of two cosmids from <TOGGLE>Schizosaccharomyces pombe</TOGGLE> chromosome III

Author

Lucas, M., Gwillam, R., Lepingle, A., Lyne, M., Rajandream, M. A., Rochet, M., Wood, V., and Gaillardin, C.

Abstract

We report the complete sequence of two cosmids, SPCC895 (38457 bp insert, EMBL Accession No. AL035247) and SPCC1322 (42068 bp insert, EMBL Accession No. AL035259), localized on chromosome III of the Schizosaccharomyces pombe genome. Fourteen Coding DNA sequences (CDSs) were identified in SPCC895 and 17 in SPCC1322. Two known genes were found in each cosmid: map2 and gms1 on SPCC895, encoding the mating type P-factor precursor and an UDP-galactose transporter, respectively, and bub1 and ade6 in SPCC1322, encoding a protein kinase and a phosphoribosylaminoimidazole carboxylase, respectively. The fission yeast K RNA gene has been localized to SPCC895. Three ribosomal proteins have been predicted among these two cosmids. Nine CDSs similar to known proteins were found on SPCC895, and seven on SPCC1322. They include putative genes for an uridylate kinase, a proteasome catalytic component, an ion transporter, a checkpoint protein, a translation initiation protein, a SNARE complex protein, a protein involved in cytoskeletal organization, a spindle pole body-associating protein, pre-mRNA splicing factor RNA helicase, a 3'–5' exonuclease for RNA 3' ss-tail, an UTP–glucose-1-phosphate uridylyltransferase, a leukotriene A4 hydrolase, a member of the RanBP7-importin β–Cse1p superfamily, a Ca++-calmodulin-dependent serine/threonine protein kinase and a prohibitin antiproliferative protein. One CDS is predicted to be an integral membrane protein. One CDS from SPCC895 is similar to a CDS of unknown function from Saccharomyces cerevisiae and three from SPCC1322 are similar to CDSs of unknown function from Candida albicans, S. cerevisiae and Sz. pombe, respectively. Finally, one CDS of SPCC895 and three of SPCC1322 correspond to orphan genes. Copyright © 2000 John Wiley & Sons, Ltd.

Published
2000

30. Sequence analysis of two cosmids from Schizosaccharomyces pombechromosome III

Author

Lucas, M., Gwillam, R., Lepingle, A., Lyne, M., Rajandream, M. A., Rochet, M., Wood, V., and Gaillardin, C.

Abstract

We report the complete sequence of two cosmids, SPCC895 (38457 bp insert, EMBL Accession No. AL035247) and SPCC1322 (42068 bp insert, EMBL Accession No. AL035259), localized on chromosome III of the Schizosaccharomyces pombegenome. Fourteen Coding DNA sequences (CDSs) were identified in SPCC895 and 17 in SPCC1322. Two known genes were found in each cosmid: map2and gms1on SPCC895, encoding the mating type P‐factor precursor and an UDP‐galactose transporter, respectively, and bub1and ade6in SPCC1322, encoding a protein kinase and a phosphoribosylaminoimidazole carboxylase, respectively. The fission yeast K RNA gene has been localized to SPCC895. Three ribosomal proteins have been predicted among these two cosmids. Nine CDSs similar to known proteins were found on SPCC895, and seven on SPCC1322. They include putative genes for an uridylate kinase, a proteasome catalytic component, an ion transporter, a checkpoint protein, a translation initiation protein, a SNARE complex protein, a protein involved in cytoskeletal organization, a spindle pole body‐associating protein, pre‐mRNA splicing factor RNA helicase, a 3′–5′ exonuclease for RNA 3′ ss‐tail, an UTP–glucose‐1‐phosphate uridylyltransferase, a leukotriene A4hydrolase, a member of the RanBP7‐importin β–Cse1p superfamily, a Ca++‐calmodulin‐dependent serine/threonine protein kinase and a prohibitin antiproliferative protein. One CDS is predicted to be an integral membrane protein. One CDS from SPCC895 is similar to a CDS of unknown function from Saccharomyces cerevisiaeand three from SPCC1322 are similar to CDSs of unknown function from Candida albicans, S. cerevisiaeand Sz. pombe, respectively. Finally, one CDS of SPCC895 and three of SPCC1322 correspond to orphan genes. Copyright © 2000 John Wiley & Sons, Ltd.

Published
2000
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32. Erratum: The genome sequence of Schizosaccharomyces pombe (Nature (2002) 415 (871-880))

Author

Wood, V., Gwilliam, R., Rajandream, M. -A, Lyne, M., Lyne, R., Stewart, A., Sgouros, J., Peat, N., Hayles, J., Baker, S., Basham, D., Bowman, S., Brooks, K., Brown, D., Brown, S., Chillingworth, T., Churcher, C., Collins, M., Connor, R., Cronin, A., Davis, P., Feltwell, T., Fraser, A., Gentles, S., Goble, A., Hamlin, N., Harris, D., Hidalgo, J., Hodgson, G., Holroyd, S., Hornsby, T., Howarth, S., Huckle, E. J., Hunt, S., Jagels, K., James, K., Jones, L., Jones, M., Leather, S., Mcdonald, S., Mclean, J., Mooney, P., Moule, S., Mungall, K., Murphy, L., Niblett, D., Odell, C., Oliver, K., O Neil, S., Pearson, D., Quail, M. A., Rabbinowitsch, E., Kim Rutherford, Rutter, S., Saunders, D., Seeger, K., Sharp, S., Skelton, J., Simmonds, M., Squares, R., Squares, S., Stevens, K., Taylor, K., Taylor, R. G., Tivey, A., Walsh, S., Warren, T., Whitehead, S., Woodward, J., Volckaert, G., Aert, R., Robben, J., Grymonprez, B., Weltjens, I., Vanstreels, E., Rieger, M., and Schäfer, M.

33. Artemis: sequence visualization and annotation.

Author

Rutherford, K, Parkhill, J, Crook, J, Horsnell, T, Rice, P, Rajandream, M A, and Barrell, B

Abstract

Artemis is a DNA sequence visualization and annotation tool that allows the results of any analysis or sets of analyses to be viewed in the context of the sequence and its six-frame translation. Artemis is especially useful in analysing the compact genomes of bacteria, archaea and lower eukaryotes, and will cope with sequences of any size from small genes to whole genomes. It is implemented in Java, and can be run on any suitable platform. Sequences and annotation can be read and written directly in EMBL, GenBank and GFF format. AVAILABITLTY: Artemis is available under the GNU General Public License from http://www.sanger.ac.uk/Software/Artemis

Published
2000
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34. Secondary DNA structure analysis of the coding strand switch regions of five Leishmania major Friedlin chromosomes.

Author

Tosato V, Ciarloni L, Ivens AC, Rajandream MA, Barrell BG, and Bruschi CV

Subjects
Animals, Computational Biology, DNA, Protozoan chemistry, Escherichia coli, Nucleic Acid Conformation, Sequence Analysis, DNA, Sequence Homology, DNA, Protozoan genetics, Genes, Switch, Leishmania major genetics
Abstract

As part of the EULEISH international genome project, a region of 74,674 nucleotides from chromosome 21 of Leishmania major Friedlin was subcloned and sequenced; and 31 new coding sequences were predicted. Of particular interest was a unique coding strand switching region covering 1.6 kb of DNA; and this was subjected to further investigation. Bioinformatic analysis of this region revealed an unusually high AT composition, a lack of putative hairpins and a strong curvature of the DNA in agreement with the structural characteristics of similar regions of other Leishmania chromosomes. These observations and a comparison with the secondary DNA structure of four other Leishmania chromosomes and chromosomes of different organisms could suggest a functional role of this region in transcription and mitotic division.

Published
2001
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35. Analysis of 41 kb of the DNA sequence from the right arm of chromosome II of Schizosaccharomyces pombe.

Author

Sánchez M, Revuelta JL, del Rey F, Gwilliam R, Skelton J, Churcher C, Rajandream MA, Wood V, Barrell B, Lyne R, Reinhardt R, Borzym K, Beck A, Moreno S, and Domínguez A

Subjects
Amino Acid Sequence, Base Sequence, Cosmids genetics, DNA, Fungal chemistry, Genes, Fungal, Genes, Mating Type, Fungal, Molecular Sequence Data, Open Reading Frames genetics, RNA, Small Nucleolar chemistry, RNA, Small Nucleolar genetics, Schizosaccharomyces chemistry, Sequence Alignment, Sequence Analysis, DNA, Sequence Homology, Amino Acid, Sequence Homology, Nucleic Acid, DNA, Fungal genetics, Schizosaccharomyces genetics
Abstract

We report the complete sequence of cosmid c18A7 (41 046 bp insert), located on the right arm of chromosome II of the Schizosaccharomyces pombe genome. The sequence, which partially overlaps with cosmids SPBC4F6 and SPBC336, contains 16 open reading frames (ORFs) capable of coding for proteins of at least 100 amino acid residues in length (one partial) and one small nucleolar RNA (snoRNA). Four known genes were found: swi10 (encoding a mating-type switching protein also involved in nucleotide excision repair); dim1 (encoding a dimethyladenosine transferase); arf1 (encoding ADP-ribosylation factor 1); and pol3 (cdc6) the partial fragment, encoding the 125 kDa catalytic subunit of the DNA polymerase type B. Six ORFs similar to known proteins were found. They include a transporter of the major facilitator superfamily class, a vacuolar sorting protein, an asparagine synthase, a nuclear protein, a reticulum oxidoreductin and a heat shock protein. Each protein product of the other six ORFs has conserved domains and can be assigned a molecular, but not a biological, function. The sequence has been submitted to the EMBL database under Accession No. AL080287., (Copyright 2001 John Wiley & Sons, Ltd.)

Published
2001
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36. A superfamily of variant genes encoded in the subtelomeric region of Plasmodium vivax.

Author

del Portillo HA, Fernandez-Becerra C, Bowman S, Oliver K, Preuss M, Sanchez CP, Schneider NK, Villalobos JM, Rajandream MA, Harris D, Pereira da Silva LH, Barrell B, and Lanzer M

Subjects
Adult, Animals, Antibodies, Protozoan immunology, Chromosomes, Artificial, Yeast, DNA, Protozoan, Gene Library, Genetic Variation, Humans, Malaria, Vivax parasitology, Multigene Family, Plasmodium falciparum genetics, Plasmodium falciparum pathogenicity, Plasmodium vivax immunology, Plasmodium vivax pathogenicity, Protozoan Proteins genetics, Protozoan Proteins immunology, Pseudogenes, Reverse Transcriptase Polymerase Chain Reaction, Telomere, Genes, Protozoan, Plasmodium vivax genetics
Abstract

The malarial parasite Plasmodium vivax causes disease in humans, including chronic infections and recurrent relapses, but the course of infection is rarely fatal, unlike that caused by Plasmodium falciparum. To investigate differences in pathogenicity between P. vivax and P. falciparum, we have compared the subtelomeric domains in the DNA of these parasites. In P. falciparum, subtelomeric domains are conserved and contain ordered arrays of members of multigene families, such as var, rif and stevor, encoding virulence determinants of cytoadhesion and antigenic variation. Here we identify, through the analysis of a continuous 155,711-base-pair sequence of a P. vivax chromosome end, a multigene family called vir, which is specific to P. vivax. The vir genes are present at about 600-1,000 copies per haploid genome and encode proteins that are immunovariant in natural infections, indicating that they may have a functional role in establishing chronic infection through antigenic variation.

Published
2001
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37. Subtelomeric sequence from the right arm of Schizosaccharomyces pombe chromosome I contains seven permease genes.

Author

Hunt C, Moore K, Xiang Z, Hurst SM, McDougall RC, Rajandream MA, Barrell BG, Gwilliam R, Wood V, Lyne MH, and Aves SJ

Subjects
Cosmids, Cytoplasm enzymology, Membrane Transport Proteins classification, Molecular Sequence Data, Phylogeny, Reading Frames, Sequence Analysis, DNA, Chromosomes, Fungal genetics, Genes, Fungal, Membrane Transport Proteins genetics, Schizosaccharomyces genetics, Telomere
Abstract

The sequence has been determined of 80 888 bp of contiguous subtelomeric DNA, including the isp5 gene, from the right arm of chromosome I of Schizosaccharomyces pombe; 27 open reading frames (ORFs) longer than 100 codons are present, giving a density of one gene per 3.0 kb. Seven of the predicted proteins are members of the major facilitator superfamily (MFS) of transport proteins, including four amino acid permease homologues, bringing this family of amino acid permease sequences to 17 in Sz. pombe, and a phylogenetic analysis is presented. Also encoded is an allantoate permease homologue, a sulphate permease homologue and a probable urea active transporter. Predicted non-membrane proteins include a 1-aminocyclopropane-1-carboxylate deaminase (ACC deaminase), a class III aminotransferase, serine acetyltransferase, protein-L-isoaspartate O-methyltransferase, alpha-glucosidase, alpha-galactosidase, esterase/lipase, oxidoreductase of the short-chain dehydrogenase/reductase (SDR) family, aldehyde dehydrogenase, formamidase, amidase, flavohaemoprotein, a putative translation initiation inhibitor and a protein with similarity to a filamentous fungal conidiation-specific protein. The remaining six ORFs are likely to encode proteins, either because they have sequence similarity with hypothetical proteins or because they are known to be transcribed. Introns are scarce in the sequenced region: only three ORFs contain introns, with only one having multiple introns. The sequenced region also contains a single Tf1 transposon long terminal repeat (LTR). The sequence is derived from cosmid clones c869, c922 and c1039 and has been submitted to the EMBL database under entries SPAC869 (Accession No. AL132779), SPAC922 (AL133522) and SPAC1039 (AL133521)., (Copyright 2001 John Wiley & Sons, Ltd.)

Published
2001
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38. Prevalence of small inversions in yeast gene order evolution.

Author

Seoighe C, Federspiel N, Jones T, Hansen N, Bivolarovic V, Surzycki R, Tamse R, Komp C, Huizar L, Davis RW, Scherer S, Tait E, Shaw DJ, Harris D, Murphy L, Oliver K, Taylor K, Rajandream MA, Barrell BG, and Wolfe KH

Subjects
Chromosomes, Fungal, Gene Rearrangement, Genome, Fungal, Candida albicans genetics, Chromosome Inversion, Evolution, Molecular, Genes, Fungal, Saccharomyces cerevisiae genetics
Abstract

Gene order evolution in two eukaryotes was studied by comparing the Saccharomyces cerevisiae genome sequence to extensive new data from whole-genome shotgun and cosmid sequencing of Candida albicans. Gene order is substantially different between these two yeasts, with only 9% of gene pairs that are adjacent in one species being conserved as adjacent in the other. Inversion of small segments of DNA, less than 10 genes long, has been a major cause of rearrangement, which means that even where a pair of genes has been conserved as adjacent, the transcriptional orientations of the two genes relative to one another are often different. We estimate that about 1,100 single-gene inversions have occurred since the divergence between these species. Other genes that are adjacent in one species are in the same neighborhood in the other, but their precise arrangement has been disrupted, probably by multiple successive multigene inversions. We estimate that gene adjacencies have been broken as frequently by local rearrangements as by chromosomal translocations or long-distance transpositions. A bias toward small inversions has been suggested by other studies on animals and plants and may be general among eukaryotes.

Published
2000
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39. Analysis of 114 kb of DNA sequence from fission yeast chromosome 2 immediately centromere-distal to his5.

Author

Xiang Z, Moore K, Wood V, Rajandream MA, Barrell BG, Skelton J, Churcher CM, Lyne MH, Devlin K, Gwilliam R, Rutherford KM, and Aves SJ

Subjects
Base Sequence, Centromere chemistry, Chromosomes, Fungal chemistry, Cosmids chemistry, Genetic Markers, Introns genetics, Molecular Sequence Data, Open Reading Frames genetics, RNA, Ribosomal chemistry, RNA, Ribosomal genetics, Schizosaccharomyces chemistry, Sequence Analysis, DNA, Sequence Homology, Amino Acid, Terminal Repeat Sequences genetics, Chromosomes, Fungal genetics, Schizosaccharomyces genetics
Abstract

One hundred and fourteen kilobase pairs (kb) of contiguous genomic sequence have been determined immediately distal to the his5 genetic marker located about 0.9 Mb from the centromere on the long arm of Schizosaccharomyces pombe chromosome 2. The sequence is contained in overlapping cosmid clones c16H5, c12D12, c24C6 and c19G7, of which 20 kb are identical to previously reported sequence from clone c21H7. The remaining 93 781 bp of sequence contains 10 known genes (cdc14, cdm1, cps1, gpa1, msh2, pck2, rip1, rps30-2, sad1 and ubl1), 32 open reading frames (ORFs) capable of coding for proteins of at least 100 amino acid residues in length, one 5S rRNA gene, one tRNA(Pro) gene, one lone Tf1-type long terminal repeat (LTR) and one lone Tf2-type LTR. There is a density of one protein-coding gene per 2.2 kb and 22 of the 42 ORFs (52%) incorporate one or more introns. Twenty-one of the novel ORFs show sequence similarities which suggest functions of their products, including a cyclin C, a MADS box transcription factor, mad2-like protein, telomere binding protein, topoisomerase II-associated protein, ATP-dependent DEAH box RNA helicase, G10 protein, ubiquitin-activating e1-like enzyme, nucleoporin, prolyl-tRNA synthetase, peptidylprolyl isomerase, delta-1-pyrroline-5-carboxylate dehydrogenase, protein transport protein, coatomer epsilon, TCP-1 chaperonin, beta-subunit of 6-phosphofructokinase, aminodeoxychorismate lyase, a phosphate transport protein and a thioredoxin.

Published
2000
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40. Current awareness on yeast.

Author

Xiang Z, Wood V, Rajandream MA, Barrell BG, Moore K, Hunt C, and Aves SJ

Subjects
Yeasts
Abstract

In order to keep subscribers up-to-date with the latest developments in their field, this current awareness service is provided by John Wiley & Sons and contains newly-published material on yeasts. Each bibliography is divided into 10 sections. 1 Books, Reviews & Symposia; 2 General; 3 Biochemistry; 4 Biotechnology; 5 Cell Biology; 6 Gene Expression; 7 Genetics; 8 Physiology; 9 Medical Mycology; 10 Recombinant DNA Technology. Within each section, articles are listed in alphabetical order with respect to author. If, in the preceding period, no publications are located relevant to any one of these headings, that section will be omitted. (5 weeks journals - search completed 31st May 2000)

Published
2000
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41. The mating-type region of Schizosaccharomyces pombe h(-S) 972: sequencing and analysis of 69 kb including the expressed mat1 locus.

Author

Xiang Z, Wood V, Rajandream MA, Barrell BG, Moore K, Hunt C, and Aves SJ

Subjects
Cosmids genetics, Genes, Fungal, Genes, Mating Type, Fungal, Molecular Sequence Data, Open Reading Frames genetics, RNA, Transfer, Gly genetics, Retroelements genetics, Sequence Analysis, DNA, Terminal Repeat Sequences genetics, Fungal Proteins genetics, Fungal Proteins metabolism, Schizosaccharomyces genetics, Schizosaccharomyces physiology
Abstract

The sequence has been determined of 68 897 bp of genomic DNA including the expressed mat1 mating-type locus from Schizosaccharomyces pombe h(-S) strain 972. The DNA sequence, located on the long arm of fission yeast chromosome II and contained in two cosmid clones, was analysed to reveal one autonomously replicating sequence, two retrotransposon long terminal repeats (LTRs), one tRNA(Gly) gene and 33 open reading frames (ORFs), of which 15 contain introns. Nine of these ORFs code for previously described genes (trt1, rpl10, rps21, nif1, sui1 (psu1), matMi, matMc, let1 and rpa4), one of which (trt1) contains 15 introns, the highest number yet recorded in a gene of S. pombe. Of the remaining 24 ORFs, sequence similarity suggests that the function of 13 of the encoded proteins may be predicted and these include four mitochondrial proteins, two transport proteins, two signalling molecules, a component of serine palmitolytransferase, a homologue of 3-methyladenine DNA glycosylase, a multifunctional alcohol dehydrogenase, a killer toxin sensitivity factor and an acetyl transferase. Six deduced sequences appear to be related to proteins of unknown function in Saccharomyces cerevisiae or S. pombe and the remaining five are hypothetical proteins.

Published
2000
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42. DNA sequencing and analysis of a 67.4 kb region from the right arm of Schizosaccharomyces pombe chromosome II reveals 28 open reading frames including the genes his5, pol5, ppa2, rip1, rpb8 and skb1.

Author

Xiang Z, Lyne MH, Wood V, Rajandream MA, Barrell BG, and Aves SJ

Subjects
Chromosome Mapping, Chromosomes, Fungal genetics, Molecular Sequence Data, Open Reading Frames, DNA, Fungal genetics, Genes, Fungal, Schizosaccharomyces genetics
Abstract

67 393 bp of contiguous DNA located between markers cdc18 and cdc14 on the right arm of fission yeast chromosome II has been sequenced as part of the European Union Schizosaccharomyces pombe genome sequencing project. The complete sequence, contained in cosmid clones c15C4 and c21H7, has been determined on both strands. Sequence analysis shows that it contains 28 open reading frames capable of coding for proteins, 16 split by one or more introns, but no tRNA, rRNA or transposon sequences. The gene density is one per 2. 4 kb. Six genes have been previously described (his5, pol5, ppa2, rip1, rpb8 and skb1) and 22 are novel. Of the novel genes, 14 have significant similarity with proteins of known function, three have similarities with proteins of unknown function and five show no extensive similarities with known proteins. Sequence similarities suggest that three of the novel genes encode ATP-dependent RNA helicases, two encode transcription factor components and others encode a G-protein, a dehydrogenase, a Rab escort protein, an Abc1-like protein, a lipase, an ATP-binding transport protein, an amino acid permease, an acid phosphatase and a mannosyltransferase., (Copyright 1999 John Wiley & Sons, Ltd.)

Published
1999
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43. Regulation of hmp gene transcription in Mycobacterium tuberculosis: effects of oxygen limitation and nitrosative and oxidative stress.

Author

Hu Y, Butcher PD, Mangan JA, Rajandream MA, and Coates AR

Subjects
Aerobiosis, Anaerobiosis, Base Sequence, Genes, Bacterial genetics, Glutathione analogs & derivatives, Glutathione pharmacology, Hydrogen Peroxide pharmacology, Molecular Sequence Data, Mycobacterium tuberculosis drug effects, Mycobacterium tuberculosis growth & development, Mycobacterium tuberculosis metabolism, Nitroprusside pharmacology, Nitroso Compounds pharmacology, Open Reading Frames genetics, Paraquat pharmacology, Promoter Regions, Genetic genetics, RNA, Bacterial analysis, RNA, Bacterial genetics, RNA, Bacterial metabolism, S-Nitrosoglutathione, Sequence Homology, Amino Acid, Transcription, Genetic drug effects, Transcription, Genetic genetics, Bacterial Proteins genetics, Gene Expression Regulation, Bacterial drug effects, Hemeproteins genetics, Mycobacterium tuberculosis genetics, Nitroso Compounds metabolism, Oxidative Stress drug effects, Oxygen metabolism
Abstract

The Mycobacterium tuberculosis hmp gene encodes a protein which is homologous to flavohemoglobin in Escherichia coli. Northern blotting analysis demonstrated that hmp transcription increased when a microaerophilic culture became oxygen limited as it entered stationary phase at 20 days. There was a fivefold increase of the hmp transcripts during early stationary phase compared with the value which was observed in the exponential growth phase. This induction of hmp transcription was not due to changes in the mRNA stability since the half-life of hmp mRNA was very short in a 20-day microaerophilic culture. No induction of hmp mRNA was observed during entry into stationary phase when the culture was continuously aerated. hmp transcription was induced after a short exposure of a late-exponential-phase culture to anaerobic conditions. These data indicate that oxygen limitation is the trigger for hmp gene transcription. In addition, when a microaerophilic culture entered into the stationary phase at 20 days, transcription of hmp increased to a small extent after exposure to S-nitrosoglutathione (a nitric oxide [NO] releaser) and sodium nitroprusside (an NO+ donor) and decreased after exposure to paraquat (a superoxide generator) and H2O2. In log phase (4 days) and late stationary phase (40 days), the transcription of hmp was unaffected by nitrosative and oxidative stress. Three primer extension products were observed. The -10 region is 100% identical to that of promoter T3 in mycobacteria and shows a strong similarity to the -10 sequence of hmp and rpoS promoters in E. coli. These observations of hmp mRNA induction in response to O2 limitation and nitrosative stress suggest that the hmp gene of M. tuberculosis may have a role in protection of the organism from NO killing under microaerophilic conditions.

Published
1999
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