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2. The CRISPR-Cas Mechanism for Adaptive Immunity and Alternate Bacterial Functions Fuels Diverse Biotechnologies

3. RNA-Independent DNA Cleavage Activities of Cas9 and Cas12a

4. Structural and functional insights into the bona fide catalytic state of Streptococcus pyogenes Cas9 HNH nuclease domain

5. Conserved DNA motifs in the type II-A CRISPR leader region

7. Coordinated Actions of Cas9 HNH and RuvC Nuclease Domains Are Regulated by the Bridge Helix and the Target DNA Sequence

8. Molecular Details of DNA Integration by CRISPR-Associated Proteins During Adaptation in Bacteria and Archaea

9. The bridge helix of Cas12a imparts selectivity in cis ‐DNA cleavage and regulates trans ‐DNA cleavage

10. Rational Engineering of CRISPR-Cas9 Nuclease to Attenuate Position-Dependent Off-Target Effects

11. CRISPR type II-A subgroups exhibit phylogenetically distinct mechanisms for prespacer insertion

13. Crystal structures of an unmodified bacterial tRNA reveal intrinsic structural flexibility and plasticity as general properties of unbound tRNAs

14. RNA-Independent DNA Cleavage Activities of Cas9 and Cas12a

15. The Revolution Continues: Newly Discovered Systems Expand the CRISPR-Cas Toolkit

16. Structural and functional insights into the bona fide catalytic state of Streptococcus pyogenes Cas9 HNH nuclease domain

18. Bridge Helix of Cas9 Modulates Target DNA Cleavage and Mismatch Tolerance

19. Nucleic Acid-Dependent Conformational Changes in CRISPR–Cas9 Revealed by Site-Directed Spin Labeling

20. DNase H Activity of Neisseria meningitidis Cas9

22. Methanopyrus kandleri topoisomerase V contains three distinct AP lyase active sites in addition to the topoisomerase active site

23. Identification of one of the apurinic/apyrimidinic lyase active sites of topoisomerase V by structural and functional studies

24. Structures of Minimal Catalytic Fragments of Topoisomerase V Reveals Conformational Changes Relevant for DNA Binding

25. Design and Synthesis of Substrate and Intermediate Analogue Inhibitors of S-Ribosylhomocysteinase

26. Crystal Structure of S-Ribosylhomocysteinase (LuxS) in Complex with a Catalytic 2-Ketone Intermediate

27. Biochemical characterization of the topoisomerase domain of Methanopyrus kandleri topoisomerase V

28. Topoisomerases

29. Probing the Catalytic Mechanism of S-Ribosylhomocysteinase (LuxS) with Catalytic Intermediates and Substrate Analogues

30. Probing the DNA sequence specificity of Escherichia coli RECA protein

31. Primary processing of CRISPR RNA by the endonuclease Cas6 in Staphylococcus epidermidis

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