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Your search keyword '"Rao, Mekhala"' showing total 8 results
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8 results on '"Rao, Mekhala"'

1. Contemporary HIV-1 consensus Env with AI-assisted redesigned hypervariable loops promote antibody binding

Author

Bai, Hongjun, primary, Lewitus, Eric, additional, Li, Yifan, additional, Thomas, Paul V., additional, Zemil, Michelle, additional, Merbah, Mélanie, additional, Peterson, Caroline E., additional, Thuraisamy, Thujitha, additional, Rees, Phyllis A., additional, Hajduczki, Agnes, additional, Dussupt, Vincent, additional, Slike, Bonnie, additional, Mendez-Rivera, Letzibeth, additional, Schmid, Annika, additional, Kavusak, Erin, additional, Rao, Mekhala, additional, Smith, Gabriel, additional, Frey, Jessica, additional, Sims, Alicea, additional, Wieczorek, Lindsay, additional, Polonis, Victoria, additional, Krebs, Shelly J., additional, Ake, Julie A., additional, Vasan, Sandhya, additional, Bolton, Diane L., additional, Joyce, M. Gordon, additional, Townsley, Samantha, additional, and Rolland, Morgane, additional

Published
2024
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2. Evolution of HIV-1 envelope towards reduced neutralization sensitivity, as demonstrated by contemporary HIV-1 subtype B from the United States

Author

Wieczorek, Lindsay, primary, Sanders-Buell, Eric, additional, Zemil, Michelle, additional, Lewitus, Eric, additional, Kavusak, Erin, additional, Heller, Jonah, additional, Molnar, Sebastian, additional, Rao, Mekhala, additional, Smith, Gabriel, additional, Bose, Meera, additional, Nguyen, Amy, additional, Dhungana, Adwitiya, additional, Okada, Katherine, additional, Parisi, Kelly, additional, Silas, Daniel, additional, Slike, Bonnie, additional, Ganesan, Anuradha, additional, Okulicz, Jason, additional, Lalani, Tahaniyat, additional, Agan, Brian K., additional, Crowell, Trevor A., additional, Darden, Janice, additional, Rolland, Morgane, additional, Vasan, Sandhya, additional, Ake, Julie, additional, Krebs, Shelly J., additional, Peel, Sheila, additional, Tovanabutra, Sodsai, additional, and Polonis, Victoria R., additional

Published
2023
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6. CLINICOPATHOLOGICAL STUDY OF ACUTE PROMYELOCYTIC LEUKEMIA: AN EXPERIENCE FROM A TEACHING HOSPITAL IN INDIA.

Author

Rao, Mekhala, Kamat, Girish, Goni, Deepak, and Balikai, Girish

Subjects
*ACUTE promyelocytic leukemia, *LEUCOCYTES, *TEACHING hospitals, *LYMPHOCYTE count, *SINUS thrombosis, *INTRACRANIAL hemorrhage, *CRANIAL sinuses
Abstract

Data on the clinicopathological features of acute promyelocytic leukemia (APL) patients from India is limited. Present study was a cross sectional study which included 18 patients of APL. Medical records of these 18 patients were reviewed to collect their clinical details and laboratory results. High risk patients (total leucocyte count >10,000/cmm) were treated with modified APML 4 protocol. Low risk patients (total leucocyte count <10,000/cmm) were treated with protocol APL-0406-Intergroup Study AL WP GIMEMA-DSIL protocol. Outcomes in terms of complete remission were assessed in both these groups. Mean haemoglobin levels was 7.03gm%, mean total leucocyte count was 30,462per cmm, mean platelet count was 27,222/cmm. Bone marrow was reported as suggestive of APL in 17 cases while in 1 case, BM aspirate was inadequate. Average percentage of abnormal promyelocytes in bone marrow was 84.25%. PT was prolonged in 15 cases, while APTT was prolonged in 3 cases. Flow cytometry analysis was done in 12 patients. All patients were CD45, MPO, CD13, CD33 and CD64 positive. Chromosomal analysis was possible in 11 cases. t(15;17)(q22;21) was identified in 6 cases (54.62%). 3 cases (27.27%) showed normal karyotype. 2 (18.18%) cases had additional cytogenetic abnormalities. All patients under high risk category attained CR. 1 patient under low risk category with additional cytogenetic abnormality died 6 days after induction therapy was started. 10 (55.55%) patients developed complications such as neutropenic sepsis, intracranial hemorrhage, differentiation syndrome, cerebral venous sinus thrombosis, pseudotumorcerebri, QTc interval prolongation, and pneumonia. [ABSTRACT FROM AUTHOR]

Published
2021
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