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179 results on '"Rasmussen, Torben Riis"'

9. Consensus on Stage and Treatment Among Multidisciplinary Teams in Lung Cancer Depends on the Stage: A Quality Assessment Study

Author

Rasmussen, Torben Riis, primary, Jakobsen, Erik, additional, Hjorthaug, Karin, additional, Larsen, Lene Unmack, additional, Meldgaard, Peter, additional, Thygesen, Jesper, additional, Bibi, Rana, additional, Møller, Lars, additional, Arshad, Arman, additional, Folkersen, Birgitte, additional, Højsgaard, Anette, additional, Saghir, Zaigham, additional, Larsen, Klaus Richter, additional, and Ravn, Jesper, additional

Published
2024
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13. Use of [ 18 F]Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography after Curative Treatment of Non-Small-Cell Lung Cancer Patients: A Nationwide Cohort Study.

Author

Guldbrandsen, Kasper Foged, Sopina, Liza, Rasmussen, Torben Riis, and Fischer, Barbara Malene

Subjects
POSITRON emission tomography, NON-small-cell lung carcinoma, COMPUTED tomography, CANCER patients, COHORT analysis, RADIOTHERAPY
Abstract

[¹⁸F]Fluorodeoxyglucose positron emission tomography/computed tomography ([¹⁸F]FDG PET/CT) is a valuable imaging tool in the post-treatment management of non-small-cell lung cancer (NSCLC). This study aimed to investigate the trends in utilization and factors associated with the use of [¹⁸F]FDG PET/CT after curative-intent treatment. Data from 13,758 NSCLC patients diagnosed between 2007 and 2020 identified in the Danish Lung Cancer Registry, who underwent curative-intent treatment, were analyzed using multivariable regression. The results showed a significant increase in the use of [¹⁸F]FDG PET/CT scans, from 10.4 per 100 patients per year in 2007 to 39.6 in 2013, followed by a period of stability. Higher utilization rates were observed in patients who received radiotherapy (22% increase compared to surgical resection) and in patients with stage II–III disease (14% and 20% increase compared to stage I, respectively). Additionally, utilization was increased when other diagnostic procedures were performed, such as MRI, ultrasound, endoscopy, and biopsy. These findings highlight an increasing reliance on [¹⁸F]FDG PET/CT in post-treatment NSCLC, especially after radiotherapy and in patients with locally advanced disease, where treatment-induced radiographic changes and an increased risk of recurrence present a significant diagnostic challenge. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Outcomes and characteristics of Danish patients undergoing a lung cancer patient pathway without getting a lung cancer diagnosis. A retrospective cohort study

Author

Therkildsen Ditte Skadhede, Christensen Jane, Andersen Ole, Thomsen Linda Aagaard, Rasmussen Torben Riis, and Christensen Niels Lyhne

Subjects
lung cancer, pathways, denmark, urgent referral, invasive examinations, Diseases of the respiratory system, RC705-779
Abstract

Introduction: The organ-specific Danish cancer patient pathways (CPPs) including standard time frames were introduced in 2008-2009 securing fast tracks for cancer diagnosis and treatment. Previous studies of the CPPs have focussed on patients getting the suspected cancer diagnosis, whereas little is known about patients not getting the cancer diagnosis for which they were examined. We aimed to describe the characteristics of patients who completed a lung cancer CPP (LCPP) without getting a LC diagnosis. Furthermore, to assess the proportion of patients who had invasive procedures performed during the LCPP and radiographic examinations of the chest conducted 30 days prior to the LCPP and during the LCPP. Moreover, we aimed to describe the proportion of patients being diagnosed with any other cancer-type than LC or with non-malignant pulmonary diseases (NMPDs) during the LCPP. Methods: The study was a retrospective population-based cohort study based on Danish national registers. Patients completing a LCPP between 1 January 2013 and 31 December 2016 without being diagnosed with LC and who were registered as initiating and completing the LCPP, a total of 35,809, were included in the study. Results: Invasive procedures were performed in 12,986 patients (37.4%) and almost all patients had CT-scans of thorax and lungs conducted 30 days prior to or during the LCPP. During the LCPP other cancer-types than LC were diagnosed in 1,537 patients (4.3% of the study population), including other primary thoracic malignancies in 312 patients, while 6,826 patients (19.1%) were diagnosed with NMPDs, most often infections or chronic respiratory diseases of lower airways. Conclusion: Besides diagnosing LC the LCPP may contribute significantly in diagnosing other primary and secondary cancers as well as non-malignant diseases.

Published
2021
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17. Validation of safety outcomes in routinely collected data: Lessons learned from a multinational postapproval safety study

Author

Arena, Patrick J., primary, Huang, Kui, additional, Löfling, Lukas, additional, Bahmanyar, Shahram, additional, Mo, Jingping, additional, Schachterle, Stephen E., additional, Nunes, Anthony P., additional, Smits, Elisabeth, additional, Juuti, Rosa, additional, Hoti, Fabian, additional, Korhonen, Pasi, additional, Adelborg, Kasper, additional, Sundbøll, Jens, additional, Rasmussen, Torben Riis, additional, Løkke, Anders, additional, and Ehrenstein, Vera, additional

Published
2022
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22. A Pilot Study on using SuperDimension when performing cryobiopsies

Author

Kronborg-White, Sissel, primary, Bendstrup, Elisabeth, additional, Gori, Leonardo, additional, Luzzi, Valentina, additional, Madsen, Line Bille, additional, Poletti, Venerino, additional, Rasmussen, Torben Riis, additional, Trigiani, Marco, additional, Vezzosi, Stefano, additional, and Tomassetti, Sara, additional

Published
2021
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25. Outcomes and characteristics of Danish patients undergoing a lung cancer patient pathway without getting a lung cancer diagnosis. A retrospective cohort study

Author

Thomsen Linda Aagaard, Rasmussen Torben Riis, Christensen Jane, Therkildsen Ditte Skadhede, Andersen Ole, and Christensen Niels Lyhne

Subjects
Pulmonary and Respiratory Medicine, Thorax, medicine.medical_specialty, Denmark, Population, pathways, Danish, Diseases of the respiratory system, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Medicine, 030212 general & internal medicine, Lung cancer, education, education.field_of_study, urgent referral, RC705-779, invasive examinations, business.industry, Cancer, Retrospective cohort study, medicine.disease, language.human_language, 030228 respiratory system, language, Population study, business, Research Article, Cohort study
Abstract

Introduction: The organ-specific Danish cancer patient pathways (CPPs) including standard time frames were introduced in 2008-2009 securing fast tracks for cancer diagnosis and treatment. Previous studies of the CPPs have focussed on patients getting the suspected cancer diagnosis, whereas little is known about patients not getting the cancer diagnosis for which they were examined. We aimed to describe the characteristics of patients who completed a lung cancer CPP (LCPP) without getting a LC diagnosis. Furthermore, to assess the proportion of patients who had invasive procedures performed during the LCPP and radiographic examinations of the chest conducted 30 days prior to the LCPP and during the LCPP. Moreover, we aimed to describe the proportion of patients being diagnosed with any other cancer-type than LC or with non-malignant pulmonary diseases (NMPDs) during the LCPP. Methods: The study was a retrospective population-based cohort study based on Danish national registers. Patients completing a LCPP between 1 January 2013 and 31 December 2016 without being diagnosed with LC and who were registered as initiating and completing the LCPP, a total of 35,809, were included in the study. Results: Invasive procedures were performed in 12,986 patients (37.4%) and almost all patients had CT-scans of thorax and lungs conducted 30 days prior to or during the LCPP. During the LCPP other cancer-types than LC were diagnosed in 1,537 patients (4.3% of the study population), including other primary thoracic malignancies in 312 patients, while 6,826 patients (19.1%) were diagnosed with NMPDs, most often infections or chronic respiratory diseases of lower airways. Conclusion: Besides diagnosing LC the LCPP may contribute significantly in diagnosing other primary and secondary cancers as well as non-malignant diseases.

Published
2021

27. Surveillance With PET/CT and Liquid Biopsies of Stage I-III Lung Cancer Patients After Completion of Definitive Therapy: A Randomized Controlled Trial (SUPER)

Author

Skougaard, Kristin, Østrup, Olga, Guldbrandsen, Kasper, Sørensen, Boe, Meldgaard, Peter, Saghir, Zaigham, Gørtz, Peter, Lonsdale, Markus Nowak, Frank, Malene Støchkel, Gerke, Oke, Rychwicka-Kielek, Beata Agnieszka, Persson, Gitte, Land, Lotte Holm, Schytte, Tine, Bodtger, Uffe, Skuladottir, Halla, Søgaard, Jes, Nielsen, Søren Steen, Rasmussen, Torben Riis, and Fischer, Barbara Malene

Published
2020
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31. 241 When MDT interdisciplinarity enhances stringency and professional quality; an analysis of multi-disciplinary team conferences

Author

Fog, Sigrid Kasper, primary, Lundvall, Lene, additional, Hagemann-Madsen, Rikke, additional, Dehn, Pernille, additional, Hillingsø, Jens, additional, Petersen, Lone Nørgård, additional, Asmussen, Jon, additional, Borre, Michael, additional, Rasmussen, Torben Riis, additional, and Boolsen, Merete Watt, additional

Published
2020
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36. Lungesygdomme

Author

Backer, Vibeke, Mortensen, Jann, Hostrup, Morten, Hansen, Hanne, Godtfredsen, Nina Skavlan, Shaker, Saher, Ulrik, Charlotte Suppli, Seersholm, Niels, Titlestad, Ingrid Louise, Hilberg, Ole, Konge, Lars, Clementsen, Paul Frost, Mellemgaard, Anders, Rasmussen, Torben Riis, Tønnesen, Philip, Hansen, Ejvind Frausing, Bülow, Hans-Henrik, Perch, Michael, Lund, Thomas Kromann, Vestbo, Jørgen, Lange, Peter, Fausbøll Mosbech, Holger, Bendstrup, Elisabeth, Jennum, Poul, Armbruster, Karin, Ringbæk, Thomas, Bødtger, Uffe, Ravn, Jesper, Sørensen, Jens Benn, de Muckadell, Ove B. Schaffalitzky, Hastrup Svendsen, Jesper, and Vilstrup, Hendrik

Published
2019

40. Vitamin B12 and its binding proteins in patients with non-small cell lung cancer referred to fast-track diagnostic work-up for lung cancer.

Author

Lo-Bisgaard, Taj, Espelund, Ulrick, Frystyk, Jan, Rasmussen, Torben Riis, Nexo, Ebba, and Arendt, Johan Frederik Håkonsen

Subjects
VITAMIN B12, NON-small-cell lung carcinoma, CARRIER proteins, BIOMARKERS, ADENOCARCINOMA, LUNG cancer diagnosis, VITAMIN B12 metabolism, LUNG cancer, LUNG tumors, ODDS ratio, RECEIVER operating characteristic curves
Abstract

High cobalamin levels have previously been associated with short-term cancer risk, including lung cancer. We explored whether levels of cobalamin and/or its binding proteins are useful as a diagnostic tool in patients suspected of non-small cell lung cancer. We included 889 patients referred for fast-track diagnosis of lung cancer to Aarhus University Hospital, Denmark. We analyzed plasma concentrations of cobalamin, transcobalamin, holotranscobalamin and haptocorrin. Information on lung cancer diagnosis was retrieved from a national database. The study cohort showed levels above reference intervals for cobalamin 12%, holotranscobalamin 25%, transcobalamin 9% and haptocorrin 36% (all p-values <.05). We observed no difference in cobalamin or holotranscobalamin levels when comparing patients diagnosed with non-small cell lung cancer (n = 161, 18%) to patients without lung cancer (n = 742, 80%), while transcobalamin showed minor differences. Haptocorrin was significantly higher in those with cancer, mainly among patients with adenocarcinoma (n = 94). A comparison of patients with the highest vs. lowest quartile levels of haptocorrin yielded an adjusted odds ratio for adenocarcinoma of 2.39 (95% confidence interval: 1.26-4.55). However, ROC curve analyzes showed haptocorrin (AUC = 0.55) and total transcobalamin (AUC = 0.56) to be poor diagnostic markers for lung cancer. A high proportion of patients suspected for non-small cell lung cancer showed increased levels of cobalamin-binding proteins. We thereby confirm the association between non-small cell lung cancer and high cobalamin levels and found that haptocorrin was the major underlying factor causing high cobalamin levels. However, none of these biomarkers were of diagnostic use among patients referred for suspected lung cancer. [ABSTRACT FROM AUTHOR]

Published
2020
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43. Programmed cell death receptor ligand 1 (PD-L1) expression: Epidermal growth factor receptor (EGFR) and Kirsten RAS (KRAS) mutations in second-line therapy (2L) non-small cell lung cancer (NSCLC) patients—A Danish cohort study.

Author

Cronin-Fenton, Deirdre, primary, Dalvi, Tapashi, additional, Hedgeman, Elizabeth, additional, Nørgaard, Mette, additional, Pedersen, Lars, additional, Hansen, Hanh, additional, Fryzek, Jon, additional, Lawrence, David, additional, Walker, Jill, additional, Mellemgaard, Anders, additional, Rasmussen, Torben Riis, additional, Shire, Norah, additional, Rigas, James R., additional, Potter, Danielle, additional, Hamilton-Dutoit, Stephen, additional, and Sørensen, Henrik Toft, additional

Published
2017
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47. Exosomal Proteins as Diagnostic Biomarkers in Lung Cancer

Author

Sandfeld-Paulsen, Birgitte, primary, Jakobsen, Kristine Raaby, additional, Bæk, Rikke, additional, Folkersen, Birgitte Holst, additional, Rasmussen, Torben Riis, additional, Meldgaard, Peter, additional, Varming, Kim, additional, Jørgensen, Malene Møller, additional, and Sorensen, Boe Sandahl, additional

Published
2016
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48. Remote symptom-monitoring of patients with advanced lung cancer: A Danish national randomized controlled trial—The ProWide study.

Author

Friis, Rasmus Blechingberg, Pappot, Helle, Hjøllund, Niels Henrik, McCulloch, Tine, Ingerslev Holt, Marianne, Persson, Gitte, Wedervang, Kim, Martini Clausen, Malene, Wahlstrøm, Stine, Holmskov Hansen, Karin, Rasmussen, Torben Riis, Dalton, Susanne Oksbjerg, Jakobsen, Erik, Linnet, Hanne, and Skuladottir, Halla

Published
2023
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