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419 results on '"Rastogi, Ashu"'

8. Performance Evaluation of a Novel Thermogram Dataset for Diabetic Foot Complications

Author

Sharma, Naveen, Mirza, Sarfaraj, Rastogi, Ashu, Mahapatra, Prasant K., Singh, Satbir, Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Saraswat, Mukesh, editor, Chowdhury, Chandreyee, editor, Kumar Mandal, Chintan, editor, and Gandomi, Amir H., editor

Published
2023
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11. Study protocol for a multicenter randomized controlled trial to compare radiofrequency ablation with surgical resection for treatment of pancreatic insulinoma

Author

Crinò, Stefano Francesco, Partelli, Stefano, Napoleon, Bertrand, Conti Bellocchi, Maria Cristina, Facciorusso, Antonio, Salvia, Roberto, Forti, Edoardo, Cintolo, Marcello, Mazzola, Michele, Ferrari, Giovanni, Carrara, Silvia, Repici, Alessandro, Zerbi, Alessandro, Lania, Andrea, Tacelli, Matteo, Arcidiacono, Paolo Giorgio, Falconi, Massimo, Larghi, Alberto, Rizzatti, Gianenrico, Alfieri, Sergio, Panzuto, Francesco, Hindryckx, Pieter, Berrevoet, Frederik, Lapauw, Bruno, Lakhtakia, Sundeep, Sundaram, Sridhar, Samanta, Jayanta, Rastogi, Ashu, and Landoni, Luca

Published
2023
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12. Normative data for insulin-like growth factor-1 (IGF-1) in healthy children and adolescents from India

Author

Ravi Teja, Kasagani Venkata, primary, Malhotra, Bhanu, additional, Vogel, Mandy, additional, Marwaha, Raman Kumar, additional, Aggarwal, Arun, additional, Pal, Rimesh, additional, Das, Liza, additional, Sachdeva, Naresh, additional, Devi, Nagita, additional, Bansal, Dipika, additional, Rastogi, Ashu, additional, Sharma, Sadhna, additional, Gajinder, Dewan, additional, Bhadada, Sanjay Kumar, additional, Ghosh, Jayaditya, additional, Monaghan, Phillip J, additional, Korbonits, Márta, additional, and Dutta, Pinaki, additional

Published
2024
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17. Management of diabetic dyslipidemia in Indians: Expert consensus statement from the Lipid Association of India

Author

Puri, Raman, Mehta, Vimal, Duell, P. Barton, Wangnoo, S.K., Rastogi, Ashu, Mohan, V., Zargar, Abdul Hamid, Kalra, Sanjay, Sahoo, Abhay Kumar, Iyengar, S.S., Yusuf, Jamal, Mukhopadhyay, Saibal, Singla, Mani Kant, Shaikh, Altamash, Kohli, Sunil, Mathur, Sandeep, Jain, Sachin, Narasingan, S.N., Gupta, Vipul, Agarwala, Rajeev, Mittal, Vinod, Varma, Amit, Panda, Jayant Kumar, Shetty, Sadanand, Yadav, Madhur, Muruganathan, A., Dabla, Pradeep, Pareek, K.K., Manoria, P.C., Nanda, Rashmi, Sattur, G.B., Pancholia, A.K., and Wong, Nathan D.

Published
2023
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28. Therapeutic high-dose vitamin D for vitamin D-deficient severe COVID-19 disease: randomized, double-blind, placebo-controlled study (SHADE-S).

Author

Singh, Ajay, Rastogi, Ashu, Puri, Goverdhan Dutt, Ganesh, Venkata, Naik, Naveen Bal, Kajal, Kamal, Kahlon, Shubhkarman, Soni, Shiv Lal, Kaloria, Narender, Saini, Kulbhushan, Hazarika, Amarjyoti, Mahajan, Varun, Singla, Karan, Bhadada, Sanjay, and Soni, Vaishali

Subjects
VITAMIN D deficiency, PATIENT safety, DIPHOSPHONATES, MULTIPLE organ failure, STATISTICAL sampling, BLIND experiment, POLYMERASE chain reaction, MULTIPLE regression analysis, TREATMENT effectiveness, RANDOMIZED controlled trials, DESCRIPTIVE statistics, HOSPITAL mortality, TERTIARY care, DIURETICS, CALCITONIN, CHOLECALCIFEROL, DRUG efficacy, ARTIFICIAL respiration, CONFIDENCE intervals, OXYGEN consumption, DATA analysis software, SURVIVAL analysis (Biometry), COVID-19, DIETARY supplements, IMMUNOMODULATORS, SARS-CoV-2, C-reactive protein, GLUCOCORTICOIDS, PROPORTIONAL hazards models
Abstract

Background efficacy of therapeutic cholecalciferol supplementation for severe COVID-19 is sparingly studied. Objective effect of single high-dose cholecalciferol supplementation on sequential organ failure assessment (SOFA) score in moderate-to-severe COVID-19. Methods participants with moderate to severe COVID-19 with PaO2/FiO2 ratio < 200 were randomized to 0.6 million IU cholecalciferol oral (intervention) or placebo. Outcomes primary outcome was change in Day 7 SOFA score and pre-specified secondary outcomes were SOFA and 28-day all-cause mortality. Results in all, 90 patients (45 each group) were included for intention-to-treat analysis. 25(OH)D3 levels were 12 (10–16) and 13 (12–18) ng/ml (P  = 0.06) at baseline; and 60 (55–65) ng/ml and 4 (1–7) ng/ml by Day 7 in vitamin D and placebo groups, respectively. The SOFA score on Day 7 was better in the vitamin D group [3 (95% CI, 2–5) versus 5 (95% CI, 3–7), P  = 0.01, intergroup difference − 2 (95% CI, −4 to −0.01); r  = 0.4]. A lower all-cause 28-day mortality [24% compared to 44% (P  = 0.046)] was observed with vitamin D. Conclusions single high-dose oral cholecalciferol supplementation on ICU admission can improve SOFA score at Day 7 and reduce in-hospital mortality in vitamin D-deficient COVID-19. ClinicalTrials.gov   id: NCT04952857 registered dated 7 July 2021. What is already known on this topic —vitamin D has immunomodulatory role. Observational and isolated intervention studies show some benefit in COVID-19. Targeted therapeutic vitamin D supplementation improve outcomes in severe COVID-19 is not studied in RCTs. What this study adds —high-dose vitamin D supplementation (0.6 Million IU) to increase 25(OH)D > 50 ng/ml is safe and reduces sequential organ failure assessment score, in-hospital mortality in moderate to severe COVID-19. How this study might affect research, practice or policy— vitamin D supplementation in vitamin D-deficient patients with severe COVID-19 is useful may be practiced. [ABSTRACT FROM AUTHOR]

Published
2024
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42. Topical Esmolol Hydrochloride as a Novel Treatment Modality for Diabetic Foot Ulcers

Author

Rastogi, Ashu, primary, Kulkarni, Sudhir A., additional, Agarwal, Sanjay, additional, Akhtar, Murtaza, additional, Arsule, Sachin, additional, Bhamre, Sudhir, additional, Bhosle, Deepak, additional, Desai, Sanjay, additional, Deshmukh, Manisha, additional, Giriraja, K. V., additional, Jagannath, Jagannath, additional, Kashiva, Reema Yuvraj, additional, Kesavan, Rajesh, additional, Khandelwal, Deepak, additional, Kolte, Sanjay, additional, Kongara, Srikanth, additional, Darivemula, Anil Kumar, additional, Madhusudan, C., additional, Pyare Saheb Qureshi, Mohammad Asif Haji, additional, Ramu, Muthu, additional, Rathod, Gunvant, additional, Yalamanchi, Sadasiva Rao, additional, Shakya, Shobhit, additional, Shetty, Prathvi, additional, Singh, Sudagar, additional, Deshpande, Supreet K., additional, Viswanathan, Vijay, additional, and Unnikrishnan, Ambika G., additional

Published
2023
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45. Effect of Monochromatic Infrared Energy on Quality of Life and Intraepidermal Nerve Fiber Density in Painful Diabetic Neuropathy: A Randomized, Sham Control Study

Author

Rastogi, Ashu, Uppula, Pavan, Saikia, Uma, and Bhansali, Anil

Subjects
Infrared radiation -- Health aspects, Phototherapy -- Testing, Neuralgia -- Care and treatment, Diabetic neuropathies -- Care and treatment, Health
Abstract

Byline: Ashu. Rastogi, Pavan. Uppula, Uma. Saikia, Anil. Bhansali Background: Monochromatic infrared energy (MIRE) has evoked mixed results for symptomatic relief of painful diabetic peripheral neuropathy (DPN). However, intraepidermal nerve-fiber [...]

Published
2021

48. PFUTnet: A Novel Deep Learning Architecture for Diabetic Foot Severity Mapping and Analysis

Author

Sharma, Naveen, Mirza, Sarfaraj, Rastogi, Ashu, Mahapatra, Prasant Kumar, and Kumar, Deepak

Abstract

Clinicians traditionally rely on manual inspection to assess the severity of diabetic foot ulcers (DFUs). However, this approach is subjective and prone to errors. Effective deep learning (DL) classifiers may minimize the users’ dependency. In this manuscript, we propose a randomized, prospective, single-blind study focusing on diabetic neuropathy foot ulceration. The study included 104 subjects, with 71 patients (50 males) having DFU (Wagner grade 2) on the plantar aspect of the foot, while the remaining 33 subjects were nondiabetic (controlled) individuals (20 males). The average age of the patients was 54.28 ± 7.45 years, and the duration of the ulcers was 5.86 ± 2.22 months. The plantar foot was divided into three regions (forefoot, midfoot, and hindfoot) to detect ulcers in various areas. A Novel DL model, plantar foot ulcer thermogram network (PFUTnet), was introduced to evaluate the severity of each area. When compared to existing DL models, such as Inception V3 and AlexNet, PFUTnet demonstrated superior performance with a higher area under curve (AUC) score of 0.98 on the thermo dataset. In terms of classification accuracy, PFUTnet achieved approximately 95%, while Inception V3 and AlexNet achieved around 93% and 90%, respectively. The proposed technique enables automated and user-independent assessment of diabetic foot wounds, allowing for precise characterization of the severity of diabetic foot conditions.

Published
2024
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50. Early and Intensive Glycemic Control for Diabetic Foot Ulcer Healing: A Prospective Observational Nested Cohort Study.

Author

Dutta, Aditya, Bhansali, Anil, and Rastogi, Ashu

Abstract

We aimed to assess the effect of glycemic control on diabetic foot ulcer (DFU) healing. A prospective nested cohort study was employed of individuals with poorly controlled diabetes (glycated hemoglobin [HbA1c] >9%) and neuropathic DFU of >2-week duration. All individuals received standard diabetes and ulcer interventions for 12 weeks. Baseline demographic characteristics, ulcer area (automated assessment by wound zoom camera), and biochemical parameters were analyzed. The cohort was stratified into ulcer healed and unhealed groups. Ulcer area and glycemic parameters at 4 and 12 weeks on follow up were compared. Forty-three individuals (47 DFU) with baseline HbA1c 11.6% and ulcer area 9.87 cm2 were enrolled. After 12 weeks, mean HbA1c was 7.2%, 17 ulcers closed (healed group) and 30 ulcers did not close (unhealed group). The median time to ulcer healing was 10 weeks. Individuals in the healed group had lower fasting blood glucose (P =.010), postprandial blood glucose (P =.006), and HbA1c at 4 weeks (P =.001), and 12 weeks (0.018) compared to the unhealed group. Cox-regression analysis that revealed lower baseline ulcer area (P =.013) and HbA1c at 4 weeks (P =.009) significantly predicted DFU healing by 12 weeks. Baseline ulcer area of >10.58 cm2 and HbA1c at 4 weeks of >8.15% predicted delayed DFU healing. In conclusion, early and intensive glycemic control in the first 4 weeks of treatment initiation is associated with greater healing of DFU independent of initial ulcer area. [ABSTRACT FROM AUTHOR]

Published
2023
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