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1. Worldwide trends in population-based survival for children, adolescents, and young adults diagnosed with leukaemia, by subtype, during 2000–14 (CONCORD-3): analysis of individual data from 258 cancer registries in 61 countries

Author

Naomi Ssenyonga, Charles Stiller, Kayo Nakata, Jaime Shalkow, Shelagh Redmond, Jean-Luc Bulliard, Fabio Girardi, Christine Fowler, Rafael Marcos-Gragera, Audrey Bonaventure, Nathalie Saint-Jacques, Pamela Minicozzi, Prithwish De, Miguel Rodríguez-Barranco, Siri Larønningen, Veronica Di Carlo, Margit Mägi, Mikhail Valkov, Karri Seppä, Dyfed Wyn Huws, Michel P Coleman, Claudia Allemani, Sabiha Bouzbid, Mokhtar Hamdi-Chérif, Lamia Kara, Kaouel Meguenni, Derbali Regagba, Sine Bayo, Traore Cheick Bougadari, Shyam Shunker Manraj, Karima Bendahhou, Akinade Ladipo, Olufemi Ogunbiyi, Nontuthuzelo Somdyala, María Agustina Chaplin, Florencia Moreno, Gladis Calabrano, Silvia Espinola, Beatriz Carballo Quintero, Rosalba Fita, Walter Laspada, Susana Ibañez, Carlos Lima, Allini Mafra Da Costa, Paulo César De Souza, Juliana Chaves, Cyntia Laporte, Maria Paula Curado, Jose Carlos de Oliveira, Claudia Veneziano, Donaldo Veneziano, Ana Beatriz Almeida, Maria Latorre, Gulnar Azevedo e Silva, Marise Rebelo, Marceli Santos, Juan Galaz, Mackarena Aparicio Aravena, Jocelyn Sanhueza Monsalve, Denise Herrmann, Solange Vargas, Victor Herrera, Claudia Uribe, Luis Eduardo Bravo, Luz Stella Garcia, Nelson Arias-Ortiz, Daniela Morantes, Daniel Jurado, María Yépez Chamorro, Sandra Delgado, Melissa Ramirez, Yaima Galán Alvarez, Priscila Torres, Fray Martínez-Reyes, Leyda Jaramillo, Rina Quinto, Jhoanna Castillo, Mariela Mendoza, Patricia Cueva, José Yépez, Bernard Bhakkan, Jacqueline Deloumeaux, Clarisse Joachim, Jonathan Macni, Rodolfo Carrillo, Jaime Shalkow Klincovstein, Rebeca Rivera Gomez, Patricia Perez, Ebert Poquioma, Guillermo Tortolero-Luna, Diego Zavala, Rafael Alonso, Enrique Barrios, Angela Eckstrand, Cindy Nikiforuk, Ryan Woods, Gail Noonan, Donna Turner, Eshwar Kumar, Bin Zhang, Jeff Dowden, Gregory Doyle, Gordon Walsh, Aniq Anam, Carol McClure, Kim Vriends, Christine Bertrand, Agnihotram Ramanakumar, Serena Kozie, Heather Stuart-Panko, Tara Freeman, Justin George, Rosa Avila, David O'Brien, Abby Holt, Lyn Almon, Kevin Ward, Sandy Kwong, Cyllene Morris, Randi Rycroft, Lloyd Mueller, Cathryn Phillips, Heather Brown, Betsy Cromartie, Julie Ruterbusch, Ann Schwartz, Gary Levin, Brad Wohler, Rana Bayakly, Scarlett Gomez, Meg McKinley, Rosemary Cress, Joni Davis, Brenda Hernandez, Christopher Johnson, Bozena Morawski, Laura Ruppert, Suzanne Bentler, Mary Charlton, Bin Huang, Thomas Tucker, Dennis Deapen, Lihua Liu, Mei-Chin Hsieh, Xiao-Cheng Wu, Molly Schwenn, Kimberly Stern, Susan Gershman, Richard Knowlton, Georgetta Alverson, Tamara Weaver, Jay Desai, Deirdre Rogers, Jeanette Jackson-Thompson, Debbi Lemons, Heather Zimmerman, Michelle Hood, Jenifer Roberts-Johnson, Whitney Hammond, Judith Rees, Karen Pawlish, Antoinette Stroup, Charles Key, Charles Wiggins, Amy Kahn, Maria Schymura, Soundarya Radhakrishnan, Chandrika Rao, Lynn Giljahn, Roberta Slocumb, Christy Dabbs, Raffaella Espinoza, Karen Aird, Todd Beran, Jim Rubertone, Stephen Slack, Junhie Oh, Tiffany Janes, Stephen Schwartz, Stephanie Chiodini, Deborah Hurley, Martin Whiteside, Saroj Rai, Melanie Williams, Kim Herget, Carol Sweeney, Alison Johnson, Mahesh Keitheri Cheteri, Patti Migliore Santiago, Steven Blankenship, Shawn Farley, Robert Borchers, Robin Malicki, Julia Espinoza, Joseph Grandpre, Brenda Edwards, Angela Mariotto, Hannah Weir, Reda Wilson, Ning Wang, Lei Yang, Jian-Shun Chen, Yu-Tong He, Guo-Hui Song, Xiao-Ping Gu, Dan Mei, Heng-Ming Ge, Tong-Hao Wu, Yan-Yan Li, De-Li Zhao, Feng Jin, Jian-Hua Zhang, Feng-Dong Zhu, Qian Junhua, Yan Lei Yang, Chun-Xiao Jiang, Wang Biao, Jian Wang, Qi-Long Li, He Yi, Xin Zhou, JianMei Dong, WeiWei Li, Fang-Xian Fu, Jian-Guo Chen, Jian Zhu, Yan-Hua Li, Yu-Qiang Lu, Min Fan, Su-Qin Huang, Guo-Ping Guo, Hua Zhaolai, Kuangrong Wei, Wan-Qing Chen, Wenqiang Wei, Hongmei Zeng, Anna Demetriou, Wai Kong Mang, Kai Cheong Ngan, Amal Kataki, Manigreeva Krishnatreya, Padmavathi Amma Jayalekshmi, Paul Sebastian, Preethi George, Aleyamma Mathew, Ambakumar Nandakumar, Reza Malekzadeh, Gholamreza Roshandel, Lital Keinan-Boker, Barbara Silverman, Hidemi Ito, Yuriko Koyanagi, Masako Sato, Fumio Tobori, Ichiro Nakata, Norihiro Teramoto, Masakazu Hattori, Yasuharu Kaizaki, Fumitaka Moki, Hiromi Sugiyama, Mai Utada, Makiko Nishimura, Keiichi Yoshida, Katsuki Kurosawa, Yuji Nemoto, Hiroto Narimatsu, Masahiko Sakaguchi, Seiki Kanemura, Michiko Naito, Rintaro Narisawa, Isao Miyashiro, Daisuke Mori, Mayuko Yoshitake, Izumi Oki, Norimasa Fukushima, Akiko Shibata, Keiichiro Iwasa, Chie Ono, Tomohiro Matsuda, Omar Nimri, Kyu-Won Jung, Young-Joo Won, Eiman Alawadhi, Amani Elbasmi, Azizah Ab Manan, Farzaana Adam, Erdenekhuu Nansalmaa, Undarmaa Tudev, Chimedsuren Ochir, Al Hareth Al Khater, Mufid El Mistiri, Gek Hsiang Lim, Yik Ying Teo, Chun-Ju Chiang, Wen-Chung Lee, Rangsiya Buasom, Suleeporn Sangrajrang, Krittika Suwanrungruang, Patravoot Vatanasapt, Karnchana Daoprasert, Donsuk Pongnikorn, Atit Leklob, Somphob Sangkitipaiboon, Sarayut Geater, Hutcha Sriplung, Okan Ceylan, Iskender Kög, Oya Dirican, Tülay Köse, Tulın Gurbuz, Füsun Emine Karašahin, Duygu Turhan, Umut Aktaş, Yakup Halat, Sultan Eser, Cankut Yakut, Merve Altinisik, Yasar Cavusoglu, Ayşe Türkköylü, Nuršen Üçüncü, Monika Hackl, Anna Zborovskaya, Olga Aleinikova, Kris Henau, Liesbet Van Eycken, Trayan Atanasov, Zdravka Valerianova, Mario Šekerija, Ladislav Dušek, Miroslav Zvolský, Lina Steinrud Mørch, Hans Storm, Charlotte Wessel Skovlund, Kaire Innos, Nea Malila, Jérémie Jégu, Michel Velten, Edouard Cornet, Xavier Troussard, Anne-Marie Bouvier, Anne-Valérie Guizard, Véronique Bouvier, Guy Launoy, Sandrine Dabakuyo Yonli, Marie-Laure Poillot, Marc Maynadié, Morgane Mounier, Lina Vaconnet, Anne-Sophie Woronoff, Mélanie Daoulas, Michel Robaszkiewicz, Jacqueline Clavel, Claire Poulalhon, Emmanuel Desandes, Brigitte Lacour, Isabelle Baldi, Camille Pouchieu, Brice Amadeo, Gaëlle Coureau, Alain Monnereau, Magali Audoin, Tania D'Almeida, Séverine Boyer, Karima Hammas, Brigitte Trétarre, Marc Colonna, Patricia Delafosse, Sandrine Plouvier, Anne Cowppli-Bony, Florence Molinié, Simona Bara, Olivier Ganry, Bénédicte Lapôtre-Ledoux, Laetitia Daubisse-Marliac, Nadine Bossard, Jacques Estève, Zoé Uhry, Roland Stabenow, Heide Wilsdorf-Köhler, Andrea Eberle, Sabine Luttmann, Imma Löhden, Alice Nennecke, Joachim Kieschke, Eunice Sirri, Christina Justenhoven, Sylke Zeissig, Bernd Holleczek, Nora Eisemann, Alexander Katalinic, Rachelle Asquez, Vijay Kumar, Eleni Petridou, Elínborg Ólafsdóttir, Laufey Tryggvadóttir, Deirdre Murray, Paul Walsh, Hildrun Sundseth, Guido Mazzoleni, Fabio Vittadello, Enzo Coviello, Francesco Cuccaro, Rocco Galasso, Giuseppe Sampietro, Michele Magoni, Antonino Ardizzone, Angelo D'Argenzio, Alessia Anna Di Prima, Antonella Ippolito, Anna Maria Lavecchia, Antonella Sutera Sardo, Gemma Gola, Paola Ballotari, Erica Giacomazzi, Stefano Ferretti, Luigino Dal Maso, Diego Serraino, Maria Vittoria Celesia, Rosa Angela Filiberti, Fabio Pannozzo, Anna Melcarne, Fabrizio Quarta, Anita Andreano, Antonio Giampiero Russo, Giuliano Carrozzi, Claudia Cirilli, Luca Cavalieri d'Oro, Magda Rognoni, Mario Fusco, Maria Francesca Vitale, Mario Usala, Rosanna Cusimano, Walter Mazzucco, Maria Michiara, Paolo Sgargi, Lorenza Boschetti, Giorgio Chiaranda, Pietro Seghini, Milena Maule, Franco Merletti, Eugenia Spata, Rosario Tumino, Pamela Mancuso, Massimo Vicentini, Tiziana Cassetti, Romano Sassatelli, Fabio Falcini, Stefania Giorgetti, Anna Luisa Caiazzo, Rossella Cavallo, Daniela Piras, Francesca Bella, Anselmo Madeddu, Anna Clara Fanetti, Sergio Maspero, Simona Carone, Antonia Mincuzzi, Giuseppa Candela, Tiziana Scuderi, Maria Adalgisa Gentilini, Roberto Rizzello, Stefano Rosso, Roberto Zanetti, Adele Caldarella, Teresa Intrieri, Fortunato Bianconi, Fabrizio Stracci, Paolo Contiero, Giovanna Tagliabue, Massimo Rugge, Manuel Zorzi, Simonetta Beggiato, Angelita Brustolin, Roberta De Angelis, Gemma Gatta, Anita Maurina, Marija Oniščuka, Mohsen Mousavi, Nadezda Lipunova, Ieva Vincerzevskienė, Dominic Agius, Neville Calleja, Sabine Siesling, Otto Visser, Tom Johannesen, Maciej Trojanowski, Tomasz Mierzwa, Jadwiga Rachtan, Kamila Kępska, Beata Kościańska, Joanna Wójcik-Tomaszewska, Marcin Motnyk, Anna Gos, Magdalena Bielska-Lasota, Joanna Didkowska, Urszula Wojciechowska, Gonçalo Forjaz de Lacerda, Raul Rego, Branca Carrito, Ana Pais, Maria José Bento, Jessica Rodrigues, Antonio Lourenço, Alexandra Mayer-da-Silva, Luminita Blaga, Daniela Coza, Lubov Gusenkova, Olga Lazarevich, Olga Prudnikova, Dmitri Mikhailovich Vjushkov, Alla Egorova, Andrey Orlov, Lidiya Pikalova, Lilia Zhuikova, Juraj Adamcik, Chakameh Safaei Diba, Vesna Zadnik, Tina Zagar, Marta De-La-Cruz, Arantza Lopez-de-Munain, Araceli Aleman, Dolores Rojas, Rosario Jiménez Chillarón, Ana Isabel Marcos Navarro, Montse Puigdemont, María-José Sánchez Perez, Paula Franch Sureda, Maria Ramos Montserrat, Maria Dolores Chirlaque López, Antonia Sánchez Gil, Eva Ardanaz, Marcela Guevara, Adela Cañete-Nieto, Rafael Peris-Bonet, Marià Carulla, Jaume Galceran, Fernando Almela, Consol Sabater, Staffan Khan, David Pettersson, Paul Dickman, Katharina Staehelin, Benjamin Struchen, Christian Herrmann, Seyed Mohsen Mousavi, Céline Egger Hayoz, Christine Bouchardy, Robin Schaffar, Philip Went, Manuela Maspoli-Conconi, Claudia Kuehni, Andrea Bordoni, Laura Ortelli, Arnaud Chiolero, Isabelle Konzelmann, Sabine Rohrmann, Miriam Wanner, John Broggio, Jem Rashbass, Deirdre Fitzpatrick, Anna Gavin, David Morrison, Catherine Thomson, Giles Greene, Dyfed Huws, Michel Coleman, Melissa Matz, Natalia Sanz, Richard Stephens, Elizabeth Chalker, Mirka Smith, Jessica Gugusheff, Hui You, Shu Qin Li, Sarah Dugdale, Julie Moore, Shoni Philpot, Rhonda Pfeiffer, Helen Thomas, Bruna Silva Ragaini, Alison Venn, Sue Evans, Luc Te Marvelde, Vedrana Savietto, Richard Trevithick, David Currow, Chris Lewis, Ssenyonga, Naomi, Stiller, Charle, Nakata, Kayo, Shalkow, Jaime, Redmond, Sheilagh, Bulliard, Jean-Luc, Girardi, Fabio, Fowler, Christine, Marcos-Gragera, Raphael, Bonaventure, Audrey, Saint-Jacques, Nathalie, Minicozzi, Pamela, De, Prithwish, Rodríguez-Barranco, Miguel, Larønningen, Siri, Di Carlo, Veronica, Mägi, Margit, Valkov, Mikhail, Seppä, Karri, Wyn Huws, Dyfed, Coleman, Michel P, Allemani, Claudia, and Mazzucco, Walter

Subjects
Adolescent, Australia, 610 Medicine & health, lymphoma, Settore MED/42 - Igiene Generale E Applicata, survival, United States, Europe, Leukemia, Myeloid, Acute, Young Adult, children, population-based/cancer registry, 360 Social problems & social services, survival, leukemia, cancer registry, Hematologic Neoplasms, leukaemia, Pediatrics, Perinatology and Child Health, Developmental and Educational Psychology, cancer, Humans, Registries, haematological malignancy, Child
Abstract

BACKGROUND Leukaemias comprise a heterogenous group of haematological malignancies. In CONCORD-3, we analysed data for children (aged 0-14 years) and adults (aged 15-99 years) diagnosed with a haematological malignancy during 2000-14 in 61 countries. Here, we aimed to examine worldwide trends in survival from leukaemia, by age and morphology, in young patients (aged 0-24 years). METHODS We analysed data from 258 population-based cancer registries in 61 countries participating in CONCORD-3 that submitted data on patients diagnosed with leukaemia. We grouped patients by age as children (0-14 years), adolescents (15-19 years), and young adults (20-24 years). We categorised leukaemia subtypes according to the International Classification of Childhood Cancer (ICCC-3), updated with International Classification of Diseases for Oncology, third edition (ICD-O-3) codes. We estimated 5-year net survival by age and morphology, with 95% CIs, using the non-parametric Pohar-Perme estimator. To control for background mortality, we used life tables by country or region, single year of age, single calendar year and sex, and, where possible, by race or ethnicity. All-age survival estimates were standardised to the marginal distribution of young people with leukaemia included in the analysis. FINDINGS 164 563 young people were included in this analysis: 121 328 (73·7%) children, 22 963 (14·0%) adolescents, and 20 272 (12·3%) young adults. In 2010-14, the most common subtypes were lymphoid leukaemia (28 205 [68·2%] patients) and acute myeloid leukaemia (7863 [19·0%] patients). Age-standardised 5-year net survival in children, adolescents, and young adults for all leukaemias combined during 2010-14 varied widely, ranging from 46% in Mexico to more than 85% in Canada, Cyprus, Belgium, Denmark, Finland, and Australia. Individuals with lymphoid leukaemia had better age-standardised survival (from 43% in Ecuador to ≥80% in parts of Europe, North America, Oceania, and Asia) than those with acute myeloid leukaemia (from 32% in Peru to ≥70% in most high-income countries in Europe, North America, and Oceania). Throughout 2000-14, survival from all leukaemias combined remained consistently higher for children than adolescents and young adults, and minimal improvement was seen for adolescents and young adults in most countries. INTERPRETATION This study offers the first worldwide picture of population-based survival from leukaemia in children, adolescents, and young adults. Adolescents and young adults diagnosed with leukaemia continue to have lower survival than children. Trends in survival from leukaemia for adolescents and young adults are important indicators of the quality of cancer management in this age group. FUNDING Children with Cancer UK, the Institut National du Cancer, La Ligue Contre le Cancer, Centers for Disease Control and Prevention, Swiss Re, Swiss Cancer Research foundation, Swiss Cancer League, Rossy Family Foundation, US National Cancer Institute, and the American Cancer Society.

Published
2022
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2. Measuring progress against cancer in the Azores, Portugal: Incidence, survival, and mortality trends and projections to 2025

Author

Gonçalo Forjaz, Raul Rego, Nadia Howlader, Huann-Sheng Chen, Angela B. Mariotto, and Vitor Rodrigues

Subjects
Adult, Male, Cancer Research, Adolescent, Epidemiology, Colorectal cancer, History, 21st Century, 03 medical and health sciences, Prostate cancer, Young Adult, 0302 clinical medicine, Neoplasms, medicine, Humans, 030212 general & internal medicine, Lung cancer, Child, Azores, Aged, Cervical cancer, Relative survival, Portugal, business.industry, Incidence (epidemiology), Incidence, Infant, Newborn, Cancer, Infant, Middle Aged, medicine.disease, Cancer registry, Oncology, 030220 oncology & carcinogenesis, Child, Preschool, Female, business, Demography
Abstract

Background Measuring progress against cancer is more accurate when trends in incidence, survival, and mortality are interpreted simultaneously. Our study aims to analyze how these key metrics have evolved over time in the Azores, Portugal. Methods Data for incident cases diagnosed in 1997–2016 and followed up through December 31, 2017 were obtained from the Azores Cancer Registry. Data for cancer deaths that occurred in 1991–2016 were obtained from Statistics Portugal. To estimate temporal trends, we applied a joinpoint model to age-adjusted rates. We estimated five-year net survival within the framework of relative survival using the Pohar-Perme estimator and predicted the number of cases and deaths in 2025. Results In men, incidence and mortality decreased for stomach, larynx, and prostate cancer. In women, mortality decreased for breast and cervical cancer. Five-year relative survival improved for several cancers, with the most pronounced improvements for prostate cancer in men and colorectal cancer in women (24.1 and 27.9 percentage point absolute increase, respectively). Conversely, incidence and mortality increased for colorectal cancer in men and lung cancer in women. The incidence and mortality burdens are both expected to increase in 2025. Conclusion Overall, progress against cancer in the Azores has been mixed, and much of the progress has been driven by advances in treatment. Statistics for lung cancer in women and colorectal cancer in men are a call to action for policymakers. Reducing tobacco use and tackling the obesity epidemic are the two public health priorities for cancer control within the region.

Published
2020

3. Infección por Chlamydia trachomatis en mujeres sexualmente activas con sintomatología genital en el territorio de Colón. 2009 Infection caused by Chlamydia trachomatis in sexually active women with genital symptomatology in Colon in 2009

Author

Luis Muy Soler, Madeline Margarita Pereira Martínez, Judith Lavin Oramas, Raúl Rego del Castillo, Ania Hernández Ortega, and Edmundo Rivera Rodríguez

Subjects
Chlamydia trachomatis, diagnóstico, prevalencia, CHLAMY-CHECK-1, diagnosis, prevalence, Medicine
Abstract

Se realizó un estudio descriptivo transversal con el objetivo de determinar la frecuencia y los factores involucrados en la infección por Chlamydia trachomatis, con un universo de 90 mujeres sexualmente activas, que acudieron a consulta de patología de cuello uterino en el Hospital Territorial Dr. Mario Muñoz Monroy, de Colón, en el tiempo comprendido del 1 de abril al 31 de junio de 2009. Se obtuvieron muestras de exudado endocervical, para realizar el ensayo inmunocromatográfico CHLAMY-CHECK-1 para Chlamydia trachomatis. Se aplicó una planilla de recolección de datos sobre algunos aspectos sociodemográficos. La prevalencia total fue de 67,7 % y se destacan los parámetros: edad igual o menor de 25 años (93,3 %), nuliparidad (27,8 %) y no uso de condón (85,2 %). Estos resultados sugieren que la infección se presenta con más frecuencia en las mujeres sexualmente activas, con 25 años o menos de edad, nulíparas y que no usan condón.We made a transversal descriptive study with the objective of determining the frequency and the facts implicated in the infection by Chlamydia trachomatis, in a universe of 90 sexually active women who assisted the consultation of uterine neck pathology in the Hospital “Dr Mario Muñoz Monroy” of Colon, in the period from April 1st to June 31st 2009. We obtained samples of endocervical exudates to make the immuno-chromatographic assay CHLAMY-CHECK-1 for C.trachomatis. We applied a form for data collection on some socio-demographic aspects. The total prevalence was 67,7 % and the following parameters stand out: age equal or less than 25 years (93,3 %), nulliparity (27,5 %) and no use of the condom (85,2 %). These results suggest that the infection is present more frequently in sexually active women, aged 25 years old or less, nulliparas, and who do not use condom.

Published
2012

4. Comportamiento de marcadores serológicos en donantes de sangre del territorio de Colón, 1998-2007 Behavior of the serologic markers in blood donors in the territory of Colon, 1998-2007

Author

Madeline M Pereira Martínez, Amauri Noda Albelo, Ania Hernández Ortega, Luis Muy Soler, Jorge Martínez Domene, and Raúl Rego del Castillo

Subjects
marcadores serológicos, antígeno de superficie del virus de la hepatitis B, anticuerpos, virus de la hepatitis C, virus de la inmunodeficiencia humana 1 y 2, donantes, sangre, prevalencia, incidencia, riesgo residual, serological markers, surface antigen of the hepatitis B virus, antibodies, Hepatitis C virus, human immunodeficiency virus 1 and 2, donors, blood, prevalence, incidence, residual risk, Medicine
Abstract

En el laboratorio de Sistema Ultra-Micro-Analítico, del banco de sangre del Hospital Territorial Universitario Dr. Mario Muñoz Monroy, del municipio Colón, provincia Matanzas, se realizó un estudio descriptivo prospectivo longitudinal, sobre el comportamiento de marcadores serológicos, donde se determinó la incidencia y prevalencia del antígeno de superficie del virus de la hepatitis B (VHB, HBsAg) y de los anticuerpos contra los virus de la hepatitis C (VHC, anti-VHC) y de la inmunodeficiencia humana 1 y 2 (VIH 1 y 2, anti-VIH 1+2), en donantes de sangre del territorio, y el estimado de infección potencial no detectada transmisible por sangre o riesgo residual (RR) en la sangre donada, en el tiempo comprendido del 1 de enero de 1998 al 31 de diciembre de 2007. La investigación se realizó con todo el universo de donantes útiles y sus respectivas donaciones de sangre, y quedó constituido por 49 749 donantes y 84 932 bolsas de sangre. Los índices de prevalencia (x 100 000 donantes), incidencia (x 100 000 donantes), y estimado de riesgo residual (x 1 000 000 de unidades de sangre donada) en el citado período de tiempo fueron: para el VHB 0,81; 0,17 y 0,20; para el VHC 0,55; 0,12 y 0,23; y para los VIH 1y2 0,005; 0,01x10-2 y 0,02 x10-3, respectivamente, índices bajos según la clasificación internacional; pero no para Cuba con respecto al HBsAg.We carried out a prospective descriptive longitudinal study on the behavior of the serologic markers in the Ultra-Micro-Analytic System laboratory, of the blood bank of the territorial university hospital Dr. Mario Muñoz Monroy, of the municipality of Colon, province of Matanzas. We determined the incidence and prevalence of the surface Hepatitis B virus antigen (HBV, HBsAg) and of the antibodies against the Hepatitis C (HCV, anti HCV) and the human immunodeficiency virus 1 and 2 (HIV 1 and 2, anti-HIV 1+2) in blood donors of the territory, and the estimate of non-detected potential infection transmissible by blood or residual risk (RR) in the donated blood, in the period from January 1st 1998 to December 31st 2007. The research was made with all the universe of utile donors and their respective blood donations, and was formed by 49 749 donors and 84 932 blood bags. The prevalence rates (x 100 000 donors), incidence (x 100 000 donors), and estimated residual risk (x 1 000 000 units of donated blood) in the quoted time period were: for the HBV 0,81; 0,17 and 0,20; for the HCV 0,55; 0,12 and 0,23, and for the HIV 1 and 2 0,005; 0,01x10-2 and 0,02x10-3 respectively, low rates according to the international classification, but not for Cuba with respect of the HBsAg.

Published
2012

5. Comportamiento de marcadores serológicos en donantes de sangre del territorio de Colón, 1998-2007

Author

Madeline M Pereira Martínez, Amauri Noda Albelo, Ania Hernández Ortega, Luis Muy Soler, Jorge Martínez Domene, and Raúl Rego del Castillo

Subjects
serological markers, surface antigen of the hepatitis b virus, antibodies, hepatitis c virus, human immunodeficiency virus 1 and 2, donors, blood, prevalence, incidence, residual risk, Medicine
Abstract

En el laboratorio de Sistema Ultra-Micro-Analítico, del banco de sangre del Hospital Territorial Universitario Dr. Mario Muñoz Monroy, del municipio Colón, provincia Matanzas, se realizó un estudio descriptivo prospectivo longitudinal, sobre el comportamiento de marcadores serológicos, donde se determinó la incidencia y prevalencia del antígeno de superficie del virus de la hepatitis B (VHB, HBsAg) y de los anticuerpos contra los virus de la hepatitis C (VHC, anti-VHC) y de la inmunodeficiencia humana 1 y 2 (VIH 1 y 2, anti-VIH 1+2), en donantes de sangre del territorio, y el estimado de infección potencial no detectada transmisible por sangre o riesgo residual (RR) en la sangre donada, en el tiempo comprendido del 1 de enero de 1998 al 31 de diciembre de 2007. La investigación se realizó con todo el universo de donantes útiles y sus respectivas donaciones de sangre, y quedó constituido por 49 749 donantes y 84 932 bolsas de sangre. Los índices de prevalencia (x 100 000 donantes), incidencia (x 100 000 donantes), y estimado de riesgo residual (x 1 000 000 de unidades de sangre donada) en el citado período de tiempo fueron: para el VHB 0,81; 0,17 y 0,20; para el VHC 0,55; 0,12 y 0,23; y para los VIH 1y2 0,005; 0,01x10-2 y 0,02 x10-3, respectivamente, índices bajos según la clasificación internacional; pero no para Cuba con respecto al HBsAg.

6. Infección por Chlamydia trachomatis en mujeres sexualmente activas con sintomatología genital en el territorio de Colón. 2009

Author

Luis Muy Soler, Madeline Margarita Pereira Martínez, Judith Lavin Oramas, Raúl Rego del Castillo, Ania Hernández Ortega, and Edmundo Rivera Rodríguez

Subjects
chlamydia trachomatis, diagnosis, prevalence, chlamy-check-1, Medicine
Abstract

Se realizó un estudio descriptivo transversal con el objetivo de determinar la frecuencia y los factores involucrados en la infección por Chlamydia trachomatis, con un universo de 90 mujeres sexualmente activas, que acudieron a consulta de patología de cuello uterino en el Hospital Territorial Dr. Mario Muñoz Monroy, de Colón, en el tiempo comprendido del 1 de abril al 31 de junio de 2009. Se obtuvieron muestras de exudado endocervical, para realizar el ensayo inmunocromatográfico CHLAMY-CHECK-1 para Chlamydia trachomatis. Se aplicó una planilla de recolección de datos sobre algunos aspectos sociodemográficos. La prevalencia total fue de 67,7 % y se destacan los parámetros: edad igual o menor de 25 años (93,3 %), nuliparidad (27,8 %) y no uso de condón (85,2 %). Estos resultados sugieren que la infección se presenta con más frecuencia en las mujeres sexualmente activas, con 25 años o menos de edad, nulíparas y que no usan condón.

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