733 results on '"Read, Robert C."'
Search Results
2. Microbiotoxicity: antibiotic usage and its unintended harm to the microbiome
- Author
-
Theodosiou, Anastasia A., Jones, Christine E., Read, Robert C., and Bogaert, Debby
- Published
- 2023
- Full Text
- View/download PDF
3. Persistence of immune responses after heterologous and homologous third COVID-19 vaccine dose schedules in the UK: eight-month analyses of the COV-BOOST trial
- Author
-
Liu, Xinxue, Munro, Alasdair P S, Wright, Annie, Feng, Shuo, Janani, Leila, Aley, Parvinder K, Babbage, Gavin, Baker, Jonathan, Baxter, David, Bawa, Tanveer, Bula, Marcin, Cathie, Katrina, Chatterjee, Krishna, Dodd, Kate, Enever, Yvanne, Fox, Lauren, Qureshi, Ehsaan, Goodman, Anna L., Green, Christopher A, Haughney, John, Hicks, Alexander, Jones, Christine E, Kanji, Nasir, van der Klaauw, Agatha A., Libri, Vincenzo, Llewelyn, Martin J, Mansfield, Rebecca, Maallah, Mina, McGregor, Alastair C, Minassian, Angela M., Moore, Patrick, Mughal, Mehmood, Mujadidi, Yama F, Belhadef, Hanane Trari, Holliday, Kyra, Osanlou, Orod, Osanlou, Rostam, Owens, Daniel R, Pacurar, Mihaela, Palfreeman, Adrian, Pan, Daniel, Rampling, Tommy, Regan, Karen, Saich, Stephen, Saralaya, Dinesh, Sharma, Sunil, Sheridan, Ray, Stokes, Matthew, Thomson, Emma C, Todd, Shirley, Twelves, Chris, Read, Robert C., Charlton, Sue, Hallis, Bassam, Ramsay, Mary, Andrews, Nick, Lambe, Teresa, Nguyen-Van-Tam, Jonathan S, Cornelius, Victoria, Snape, Matthew D, and Faust, Saul N
- Published
- 2023
- Full Text
- View/download PDF
4. A Questionnaire-based Study Exploring Participant Perspectives in a Perinatal Human Challenge Trial
- Author
-
Bevan, James H. J., Theodosiou, Anastasia A., Corner, James, Dorey, Robert B., Read, Robert C., and Jones, Christine E.
- Published
- 2023
- Full Text
- View/download PDF
5. Antibiotics for lower respiratory tract infection in children presenting in primary care: ARTIC-PC RCT
- Author
-
Little Paul, Francis Nick A, Stuart Beth, O’Reilly Gilly, Thompson Natalie, Becque Taeko, Hay Alastair D, Wang Kay, Sharland Michael, Harnden Anthony, Yao Guiqing, Raftery James, Zhu Shihua, Little Joseph, Hookham Charlotte, Rowley Kate, Euden Joanne, Harman Kim, Coenen Samuel, Read Robert C, Woods Catherine, Butler Christopher C, Faust Saul N, Leydon Geraldine, Wan Mandy, Hood Kerenza, Whitehurst Jane, Richards-Hall Samantha, Smith Peter, Thomas Michael, Moore Michael, and Verheij Theo
- Subjects
respiratory tract infections ,antimicrobial drug resistance ,antibacterial agents ,cough ,public health ,primary care ,Medical technology ,R855-855.5 - Abstract
Background Antimicrobial resistance is a global health threat. Antibiotics are commonly prescribed for children with uncomplicated lower respiratory tract infections, but there is little randomised evidence to support the effectiveness of antibiotics in treating these infections, either overall or relating to key clinical subgroups in which antibiotic prescribing is common (chest signs; fever; physician rating of unwell; sputum/rattly chest; shortness of breath). Objectives To estimate the clinical effectiveness and cost-effectiveness of amoxicillin for uncomplicated lower respiratory tract infections in children both overall and in clinical subgroups. Design Placebo-controlled trial with qualitative, observational and cost-effectiveness studies. Setting UK general practices. Participants Children aged 1–12 years with acute uncomplicated lower respiratory tract infections. Outcomes The primary outcome was the duration in days of symptoms rated moderately bad or worse (measured using a validated diary). Secondary outcomes were symptom severity on days 2–4 (0 = no problem to 6 = as bad as it could be); symptom duration until very little/no problem; reconsultations for new or worsening symptoms; complications; side effects; and resource use. Methods Children were randomised to receive 50 mg/kg/day of oral amoxicillin in divided doses for 7 days, or placebo using pre-prepared packs, using computer-generated random numbers by an independent statistician. Children who were not randomised could participate in a parallel observational study. Semistructured telephone interviews explored the views of 16 parents and 14 clinicians, and the data were analysed using thematic analysis. Throat swabs were analysed using multiplex polymerase chain reaction. Results A total of 432 children were randomised (antibiotics, n = 221; placebo, n = 211). The primary analysis imputed missing data for 115 children. The duration of moderately bad symptoms was similar in the antibiotic and placebo groups overall (median of 5 and 6 days, respectively; hazard ratio 1.13, 95% confidence interval 0.90 to 1.42), with similar results for subgroups, and when including antibiotic prescription data from the 326 children in the observational study. Reconsultations for new or worsening symptoms (29.7% and 38.2%, respectively; risk ratio 0.80, 95% confidence interval 0.58 to 1.05), illness progression requiring hospital assessment or admission (2.4% vs. 2.0%) and side effects (38% vs. 34%) were similar in the two groups. Complete-case (n = 317) and per-protocol (n = 185) analyses were similar, and the presence of bacteria did not mediate antibiotic effectiveness. NHS costs per child were slightly higher (antibiotics, £29; placebo, £26), with no difference in non-NHS costs (antibiotics, £33; placebo, £33). A model predicting complications (with seven variables: baseline severity, difference in respiratory rate from normal for age, duration of prior illness, oxygen saturation, sputum/rattly chest, passing urine less often, and diarrhoea) had good discrimination (bootstrapped area under the receiver operator curve 0.83) and calibration. Parents found it difficult to interpret symptoms and signs, used the sounds of the child’s cough to judge the severity of illness, and commonly consulted to receive a clinical examination and reassurance. Parents acknowledged that antibiotics should be used only when ‘necessary’, and clinicians noted a reduction in parents’ expectations for antibiotics. Limitations The study was underpowered to detect small benefits in key subgroups. Conclusion Amoxicillin for uncomplicated lower respiratory tract infections in children is unlikely to be clinically effective or to reduce health or societal costs. Parents need better access to information, as well as clear communication about the self-management of their child’s illness and safety-netting. Future work The data can be incorporated in the Cochrane review and individual patient data meta-analysis. Trial registration This trial is registered as ISRCTN79914298. Funding This project was funded by the National Institute for Health and Care Research (NIHR) Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 27, No. 9. See the NIHR Journals Library website for further project information. Plain language summary Background Children are commonly prescribed antibiotics for chest infections, but such infections are becoming resistant to antibiotics, and it is not clear if antibiotics work in treating them. Methods A total of 432 children who saw their general practitioner with a chest infection were given either an antibiotic (amoxicillin) or a placebo (no antibiotic) for 7 days. Symptom diaries documented the infection’s duration and its side effects. Children not in the placebo study were able to participate in another study that documented the same outcomes (an ‘observational study’). We interviewed parents, doctors and nurses about their observations and concerns. Our patient and public involvement and engagement work with parents indicated that a 3-day symptom reduction was required to justify giving antibiotics. Results After seeing the doctor, parents whose children received antibiotics rated infective symptoms as moderately bad or worse for 5 days, and parents whose children received the placebo rated these for 6 days. Side effects and complications were similar in the two groups. Findings were similar when including the results of the observational study, and for children in whose chest the doctor could hear wheeze or rattles; who had fever; who were rated by the doctor as more unwell, who were short of breath, or who had had bacteria detected in the throat. The costs to the NHS per child were similar (antibiotics, £29; placebo, £26), and the wider costs to society were the same (antibiotics, £33; placebo, £33). Parents found it difficult to interpret their child’s symptoms, and commonly used the sound of the cough to judge severity. Parents commonly consulted to receive an examination and reassurance, and accepted that antibiotics should be used only when ‘necessary’. Clinicians noted a reduction in parents’ expectations for antibiotics. Conclusion Amoxicillin for chest infections in children is unlikely to be effective. General practitioners should support parents to self-manage at home and give clear communication about when and how to seek medical help if they continue to be concerned. Scientific summary Background Antimicrobial resistance (AMR) is a global public health threat. Antibiotics are very commonly prescribed for children presenting with uncomplicated lower respiratory tract infection, but there is little randomised evidence of the effectiveness of antibiotics for treating these, either overall or among key clinical subgroups. Objective The objective was to undertake a trial of antibiotics for children presenting with lower respiratory tract infection in primary care, with a parallel observational study. Aims The aims were to: 1.estimate the effectiveness of amoxicillin overall and in key clinical subgroups of children presenting with uncomplicated (non-pneumonic) lower respiratory tract infection in primary care 2.estimate the cost-effectiveness of antibiotics overall in children presenting with uncomplicated (non-pneumonic) lower respiratory tract infection in primary care 3.explore the estimates of effectiveness according to key pathophysiological subgroups (the presence of bacterial pathogens) 4.explore which variables predict poor prognosis and develop a prediction model for poor prognosis 5.explore the views of parents and clinicians regarding management of children and participation in the trial. Design This was a placebo-controlled trial with qualitative research and health economic analysis, and a parallel observational cohort. Setting UK general practices. Participants Participants were children aged between 6 months and 12 years presenting to primary care with an acute lower respiratory tract infection, defined as one in which an acute cough is the predominant symptom and judged by the general practitioner (GP) to be infective in origin, lasting < 21 days, and with other symptoms or signs localising to the lower respiratory tract (shortness of breath, sputum, pain), and in whom pneumonia was not suspected clinically. Outcomes The primary outcome was the duration in days of symptoms rated moderately bad or worse (measured using a validated diary). The secondary outcomes were symptom severity on days 2–4 (0 = no problem to 6 = as bad as it could be); symptom duration until very little/no problem; reconsultations for new or worsening symptoms; progression of illness sufficient to require hospital assessment; side effects; and resource use. Ethics The protocol was approved by the South West – Central Bristol Research Ethics Committee (reference 15/SW/0300). Methods Children were randomised to receive 50 mg/kg/day oral amoxicillin in divided doses for 7 days, or placebo, using pre-prepared packs randomised by an independent statistician using computer-generated random numbers. Children whom clinicians were unwilling to randomise or parents who were unwilling for their child to be randomised were invited to participate in an observational study in which the same data as in the trial were collected. The revised target sample size (agreed with the Trial Steering Committee, the Data Monitoring and Ethics Committee and the funder) to detect an important clinical difference of 3 days in symptoms duration was 298 participants for 80% power and 398 participants for 90% power. Semistructured interviews were used to explore the views of management and the decisions to participate in the trial. Parents were purposefully sampled by whether they took part in the trial or the observational study, and by practice. Clinicians who recruited participants into the study were also invited to take part in a telephone interview. The interviews were analysed using thematic analysis. Throat swabs were analysed for the presence of bacteria and viruses by multiplex polymerase chain reaction. Statistical analysis Cox regression was used for the primary outcome and for total symptom duration, adjusting for age, baseline symptom severity, prior duration of illness and comorbidity. Linear regression was used for symptom severity, and logistic regression was used for reconsultation, progression of illness and side effects, adjusting for the same baseline covariates as in the primary analysis. Analysis was by intention to treat, as randomised regardless of non-adherence or protocol deviations. Multiple imputation was used as the primary analysis, comprising all variables from the analysis model and any predictors of missingness, and using 100 imputations. Prespecified subgroup analyses were carried out on chest signs, sputum/rattly chest, history of fever, physician rating of unwell, shortness of breath, oxygen saturation below 95%, and STARWAVe clinical prediction rule for hospitalisation. For the observational data set, stratification by propensity scores was used to control for confounding by indication, and the data were merged with the trial data set to facilitate more powerful analyses. A logistic regression model was built to predict the progression of illness, and discrimination was assessed using estimates of area under the receiver operator curve that were bootstrapped for internal validation. Health economic analysis Both cost-effectiveness (in GBP per unit of primary outcome) and cost per quality-adjusted life-year (QALY) were estimated. The base case took an NHS perspective, but some non-NHS costs were also included (remedies and time off work). Resource use data were collected by a notes review in primary care supplemented by the diary. Unit costs of primary care consultation, community services, outpatient visits and accident and emergency attendances were costed based on the Personal Social Services Research Unit. National reference costs were used to cost hospital stay based on corresponding diagnostic categories. Medications were priced based on the British National Formulary. All costs were based on 2019 prices. QALYs were based on the EQ-5D-Y (EuroQol-5 Dimensions Youth), collected weekly, and on the recommended national tariff. Trial results A total of 432 children were randomised (antibiotics, n = 221; placebo, n = 211). The duration of moderately bad symptoms was similar in the two groups [median 5 vs. 6 days, respectively; hazard ratio (HR) 1.13, 95% confidence interval (CI) 0.90 to 1.42]. Return with new or worsening symptoms (29.7% vs. 38.2%; risk ratio 0.80, 95% CI 0.58 to 1.05), progression of illness requiring hospital assessment (2.4% vs 2.0%) and side effects (38% vs. 34%) were also similar in the two groups. A small difference in mean symptom severity on days 2–4 (1.8 vs. 2.1 points; difference 0.28 points, 95% CI 0.04 to 0.51) is unlikely to be clinically meaningful. No differences were seen for the primary outcome in the five prespecified clinical subgroups in which antibiotic prescribing is common: chest signs subgroup (antibiotics 6 days vs. placebo 6 days; HR 0.97, 95% CI 0.65 to 1.43), sputum/rattly chest (5 vs. 7 days; 1.16, 95% CI 0.83 to 1.64), fever (5 vs. 6 days; 1.23, 95% CI 0.88 to 1.73), physician rating of unwell (5 vs. 6 days; 1.25, 95% CI 0.85 to 1.83) and shortness of breath (5 vs. 6 days; 1.13, 95% CI 0.72 to 1.77). There was also no evidence that the presence of bacteria in the throat swab mediated antibiotic effectiveness. Estimates from complete cases (n = 317) were very similar, as were estimates from a per-protocol analysis for children taking 11 or more of the of 15 doses in the first 5 days. NHS costs per child were slightly higher with antibiotics (antibiotic, £29; placebo, £26) and non-NHS costs were the same (antibiotics, £33; placebo, £33), but QALY data were too incomplete for robust imputation. The incremental cost per QALY (incremental cost-effectiveness ratio) was £30,851 (95% CI –£73,639 to £109,429) based on estimates from the means of complete cases and £6417 (95% CI –£12,240 to £20,535) based on the estimates using imputed data. Observational study A total of 326 children were recruited to the observational study. The estimate of benefit of antibiotics for the primary outcome was similar to that in the trial (HR 1.16, 95% CI 0.95 to 1.41). A prognostic model to predict the progression of illness consisting of seven variables (baseline severity, difference in respiratory rate from normal for age, duration of prior illness, oxygen saturation, sputum/rattly chest, passing urine less often and diarrhoea) had good discrimination (bootstrapped area under the receiver operator curve 0.85) and calibration, and a three-item model (respiratory rate, oxygen saturation, sputum/rattly chest) also performed well (area under the receiver operator curve 0.81). Qualitative results Thirty semistructured telephone interviews were conducted with 16 parents and 14 clinicians. Parents found it difficult to interpret the symptoms and signs, and commonly used the sounds of the cough to judge severity, which highlights the need to provide better information to support parents. Many parents said that the main reason for consulting was to receive a clinical examination and reassurance regarding illness severity. Parents acknowledged that antibiotics should be used only when ‘necessary’, and many of the clinicians also noted a shift in parents’ expectations about antibiotics and that they were satisfied with a clinical assessment, reassurance and advice. Decisions to take part in the trial were influenced by the perceived risks associated with taking a placebo compared with immediate antibiotics, and with taking antibiotics unnecessarily. Clear communication about the self-management of their child’s illness and ‘safety-netting’ (information on the natural course of the illness and advice about when it might be necessary to reconsult) were identified as important when implementing ‘no antibiotic’ prescribing strategies to reassure parents and to support prescribing decisions. Limitations The study was underpowered to detect small benefits in the key clinical subgroups. The trial included children who were more unwell than those in recent large generalisable cohorts, which suggests that, if anything, the benefit of antibiotics has been overestimated. Given the very large numbers of missing data, the imputed estimates in the economic analysis must be viewed with caution. If the costs of AMR were included, then these estimates of cost-effectiveness would worsen. Conclusions Implications for clinical care Amoxicillin for uncomplicated chest infections in children makes little difference to symptom burden or to health or societal costs. Better access to information is needed to support parents’ decision-making, as is clear clinician communication about the self-management of their child’s illness and safety-netting. A prognostic score using variables that can be collected very easily during consultations can be used to identify children who are at low risk of illness progression. Implications for future research •The data can be incorporated in a Cochrane review and an individual patient data meta-analysis. •Further work on the incremental QALY gain from antibiotics is needed, assessing a range of models and their implications when imputing missing QALY data, and better evidence is needed about how to incorporate AMR resource implications in modelling. •The prognostic score should be externally validated and could be developed as an app with automated outputs, and thereafter used as a tool to reduce antibiotic prescribing for antimicrobial stewardship interventions. Trial registration This trial is registered as ISRCTN79914298. Funding This project was funded by the National Institute for Health and Care Research (NIHR) Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 27, No. 9. See the NIHR Journals Library website for further project information.
- Published
- 2023
- Full Text
- View/download PDF
6. Artificial intelligence, machine learning and deep learning: Potential resources for the infection clinician
- Author
-
Theodosiou, Anastasia A. and Read, Robert C.
- Published
- 2023
- Full Text
- View/download PDF
7. The role of public involvement in the design of the first SARS-CoV-2 human challenge study during an evolving pandemic
- Author
-
Piggin, Maria, Smith, Emma, Mankone, Peter, Ndegwa, Leah, Gbesemete, Diane, Pristerà, Philippa, Bahrami-Hessari, Michael, Johnson, Halle, Catchpole, Andrew P., Openshaw, Peter J.M., Chiu, Christopher, Read, Robert C., Ward, Helen, and Barker, Caroline
- Published
- 2022
- Full Text
- View/download PDF
8. Prior exposure to B. pertussis shapes the mucosal antibody response to acellular pertussis booster vaccination
- Author
-
van Schuppen, Evi, Fröberg, Janeri, Venkatasubramanian, Prashanna Balaji, Versteegen, Pauline, de Graaf, Hans, Holubová, Jana, Gillard, Joshua, van Gageldonk, Pieter G. M., Joosten, Irma, de Groot, Ronald, Šebo, Peter, Berbers, Guy A. M., Read, Robert C., Huynen, Martijn A., de Jonge, Marien I., and Diavatopoulos, Dimitri A.
- Published
- 2022
- Full Text
- View/download PDF
9. Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults
- Author
-
Killingley, Ben, Mann, Alex J., Kalinova, Mariya, Boyers, Alison, Goonawardane, Niluka, Zhou, Jie, Lindsell, Kate, Hare, Samanjit S., Brown, Jonathan, Frise, Rebecca, Smith, Emma, Hopkins, Claire, Noulin, Nicolas, Löndt, Brandon, Wilkinson, Tom, Harden, Stephen, McShane, Helen, Baillet, Mark, Gilbert, Anthony, Jacobs, Michael, Charman, Christine, Mande, Priya, Nguyen-Van-Tam, Jonathan S., Semple, Malcolm G., Read, Robert C., Ferguson, Neil M., Openshaw, Peter J., Rapeport, Garth, Barclay, Wendy S., Catchpole, Andrew P., and Chiu, Christopher
- Published
- 2022
- Full Text
- View/download PDF
10. Effect of priming interval on reactogenicity, peak immunological response, and waning after homologous and heterologous COVID-19 vaccine schedules: exploratory analyses of Com-COV, a randomised control trial
- Author
-
Munro, Alasdair P.S., Bartholomew, Jazz, Presland, Laura, Horswill, Sarah, Warren, Sarah, Varkonyi-Clifford, Sophie, Saich, Stephen, Adams, Kirsty, Ricamara, Marivic, Turner, Nicola, Yee Ting, Nicole Y., Whittley, Sarah, Rampling, Tommy, Desai, Amisha, Brown, Claire H., Qureshi, Ehsaan, Gokani, Karishma, Naker, Kush, Kellett Wright, Johanna K., Williams, Rachel L., Riaz, Tawassal, Penciu, Florentina D., Carson, Amy, Di Maso, Claudio, Mead, Gracie, Howe, Elizabeth G., Vichos, Iason, Ghulam Farooq, Mujtaba, Noristani, Rabiullah, Yao, Xin L., Oldfield, Neil J., Hammersley, Daniel, Belton, Sue, Royal, Simon, San Francisco Ramos, Alberto, Hultin, Cecilia, Galiza, Eva P., Crook, Rebecca, Bula, Marcin, Fyles, Fred, Burhan, Hassan, Maelin, Flora, Hughes, Elen, Okenyi, Emmanuel, Shaw, Robert H, Liu, Xinxue, Stuart, Arabella S V, Greenland, Melanie, Aley, Parvinder K, Andrews, Nick J, Cameron, J Claire, Charlton, Sue, Clutterbuck, Elizabeth A, Collins, Andrea M, Dejnirattisai, Wanwisa, Dinesh, Tanya, Faust, Saul N, Ferreira, Daniela M, Finn, Adam, Green, Christopher A, Hallis, Bassam, Heath, Paul T, Hill, Helen, Lambe, Teresa, Lazarus, Rajeka, Libri, Vincenzo, Long, Fei, Mujadidi, Yama F, Plested, Emma L, Morey, Ella R, Provstgaard-Morys, Samuel, Ramasamy, Maheshi N, Ramsay, Mary, Read, Robert C, Robinson, Hannah, Screaton, Gavin R, Singh, Nisha, Turner, David P J, Turner, Paul J, Walker, Laura L, White, Rachel, Nguyen-Van-Tam, Jonathan S, and Snape, Matthew D
- Published
- 2022
- Full Text
- View/download PDF
11. Antibiotics for lower respiratory tract infection in children presenting in primary care (ARTIC-PC): the predictive value of molecular testing
- Author
-
Little, Paul, Read, Robert C., Becque, Taeko, Francis, Nick A., Hay, Alastair D., Stuart, Beth, O'Reilly, Gilly, Thompson, Natalie, Hood, Kerenza, Faust, Saul, Wang, Kay, Moore, Michael, and Verheij, Theo
- Published
- 2022
- Full Text
- View/download PDF
12. Safety, immunogenicity, and reactogenicity of BNT162b2 and mRNA-1273 COVID-19 vaccines given as fourth-dose boosters following two doses of ChAdOx1 nCoV-19 or BNT162b2 and a third dose of BNT162b2 (COV-BOOST): a multicentre, blinded, phase 2, randomised trial
- Author
-
Munro, Alasdair P S, Feng, Shuo, Janani, Leila, Cornelius, Victoria, Aley, Parvinder K, Babbage, Gavin, Baxter, David, Bula, Marcin, Cathie, Katrina, Chatterjee, Krishna, Dodd, Kate, Enever, Yvanne, Qureshi, Ehsaan, Goodman, Anna L, Green, Christopher A, Harndahl, Linda, Haughney, John, Hicks, Alexander, van der Klaauw, Agatha A, Kanji, Nasir, Libri, Vincenzo, Llewelyn, Martin J, McGregor, Alastair C, Minassian, Angela M, Moore, Patrick, Mughal, Mehmood, Mujadidi, Yama F, Holliday, Kyra, Osanlou, Orod, Osanlou, Rostam, Owens, Daniel R, Pacurar, Mihaela, Palfreeman, Adrian, Pan, Daniel, Rampling, Tommy, Regan, Karen, Saich, Stephen, Bawa, Tanveer, Saralaya, Dinesh, Sharma, Sunil, Sheridan, Ray, Maallah, Mina, Thomson, Emma C, Todd, Shirley, Twelves, Chris, Read, Robert C, Charlton, Sue, Hallis, Bassam, Ramsay, Mary, Andrews, Nick, Lambe, Teresa, Nguyen-Van-Tam, Jonathan S, Snape, Matthew D, Liu, Xinxue, Faust, Saul N, Riordan, Andrew, Ustianowski, Andrew, Rogers, Chris, Katechia, Kashyap, Cooper, Alison, Freedman, Andrew, Hughes, Rachel, Grundy, Lynne, Tudor Jones, Lona, Harrison, Elizabeth, Snashall, Emma, Mallon, Lewis, Burton, Katharine, Storton, Kim, Munusamy, Malathi, Tandy, Bridget, Egbo, Akamino, Cox, Stephen, Ahmed, Nabeela Nazir, Shenoy, Anil, Bousfield, Rachel, Wixted, Donna, Gutteridge, Helen, Mansfield, Becky, Herbert, Christopher, Murira, Jennifer, Calderwood, James, Barker, Dominique, Brandon, Jacqueline, Tulloch, Hayley, Colquhoun, Suzie, Thorp, Helen, Radford, Helen, Evans, Julie, Baker, Helena, Thorpe, Jeanette, Batham, Sally, Hailstone, Jessica, Phillips, Rachael, Kumar, Dileep, Westwell, Fran, Sturdy, Ann, Barcella, Lara, Soussi, Najwa, Mpelembue, Mushiya, Raj, Sreena, Sharma, Rajni, Corrah, Tumena, John, Laurence, Whittington, Ashley, Roche, Siobhan, Wagstaff, Lynda, Farrier, Adam, Bisnauthsing, Karen, Abeywickrama, Movin, Spence, Niamh, Packham, Alice, Serafimova, Teona, Aslam, Suahil, McGreevy, Caitlin, Borca, Alessandro, DeLosSantosDominguez, Pamela, Palmer, Emily, Broadhead, Samantha, Farooqi, Sadaf, Piper, Jo, Weighell, Rowena, Pickup, Lorinda, Shamtally, Djamila, Domingo, Jason, Kourampa, Evgenia, Hale, Colin, Gibney, Jennifer, Stackpoole, Michael, Rashid-Gardner, Zalina, Lyon, Rebecca, McDonnell, Chloe, Cole, Christine, Stewart, Anna, McMillan, Gillian, Savage, Mary, Beckett, Helen, Moorbey, Chantelle, Desai, Amisha, Brown, Claire, Naker, Kush, Gokani, Karishma, Trinham, Charlotte, Sabine, Charlette, Moore, Sophie, Hurdover, Steve, Justice, Edwin, Stone, Megan, Plested, Emma, Ferreira Da Silva, Carla, White, Rachel, Robinson, Hannah, Turnbull, Iain, Morshead, Gertraud, Drake-Brockman, Rachael, Smith, Catherine, Li, Grace, Kasanyinga, Mwila, Clutterbuck, Elizabeth A, Bibi, Sagida, Singh, Michael, Champaneri, Trishna, Irwin, Margaret, Khan, Mohammed, Kownacka, Alicia, Nabunjo, Martha, Osuji, Carol, Hladkiwskyj, John, Galvin, Dominic, Patel, Gita, Grierson, Jacques, Males, Samantha, Askoolam, Krishna, Barry, Joshua, Mouland, Johanna, Longhurst, Beverley, Moon, Maria, Giddins, Beth, Pereira Dias Alves, Carlota, Richmond, Leah, Minnis, Christine, Baryschpolec, Sonia, Elliott, Scott, Fox, Lauren, Graham, Victoria, Baker, Natalie, Godwin, Kerry, Buttigieg, Karen, Knight, Chanice, Brown, Phillip, Lall, Paminder, Shaik, Imam, Chiplin, Emily, Brunt, Emily, Leung, Stephanie, Allen, Lauren, Thomas, Steve, Fraser, Sara, Choi, Bea, Gouriet, Jade, Perkins, Jonathan, Gowland, Andrew, Macdonald, Jonathan, Seenan, John Paul, Starinskij, Igor, Seaton, Andrew, Peters, Erica, Singh, Stephen, Gardside, Ben, Bonnaud, Avril, Davies, Ceri, Gordon, Elizabeth, Keenan, Samantha, Hall, Jane, Wilkins, Suzanne, Tasker, Suzanne, James, Rob, Seath, Ingrid, Littlewood, Kelly, Newman, Joseph, Boubriak, Iryna, Suggitt, Debbie, Haydock, Helen, Bennett, Sara, Woodyatt, Wiesia, Hughes, Kerry, Bell, Judith, Coughlan, Tricia, van Welsenes, Donald, Kamal, Mohammed, Cooper, Chris, Tunstall, Simon, Ronan, Nicholas, Cutts, Rebecca, Dare, Tracey, Yim, Yee Ting Nicole, Whittley, Sarah, Hamal, Shama, Ricamara, Marivic, Adams, Kirsty, Baker, Holly, Driver, Kimberley, Turner, Nicola, Rawlins, Todd, Roy, Subarna, Merida-Morillas, Marta, Sakagami, Yukari, Andrews, Antonette, Goncalvescordeiro, Lillian, Stokes, Matthew, Ambihapathy, Wythehi, Spencer, Joanne, Parungao, Nina, Berry, Lisa, Cullinane, James, Presland, Laura, Ross Russell, Amy, Warren, Sarah, Baker, Jonathan, Oliver, Abigail, Buadi, Amanda, Lee, Kim, Haskell, Louise, Romani, Rossana, Bentley, Ian, Whitbred, Tim, Fowler, Simon, Gavin, John, Magee, Alan, Watson, Tara, Nightingale, Kari, Marius, Phedra, Summerton, Eloise, Locke, Emily, Honey, Thomas, Lingwood, Aidan, de la Haye, Anastasia, Elliott, Ryan Stephen, Underwood, Karen, King, Mikayala, Davies-Dear, Sharon, Horsfall, Emily, Chalwin, Olivia, Burton, Holly, Edwards, Christopher J, Welham, Benjamin, Appleby, Kim, Dineen, Emily, Garrahy, Sarah, Hall, Fran, Ladikou, Eleni, Mullan, Dee, Hansen, Daniel, Campbell, Marion, Dos Santos, Filipa, Lakeman, Nicki, Branney, Debbie, Vamplew, Luke, Hogan, Alison, Frankham, Jorden, Wiselka, Martin, Vail, Denny, Wenn, Victoria, Renals, Valerie, Ellis, Kate, Lewis-Taylor, Jessica, Habash-Bailey, Haniah, Magan, Javier, and Hardy, Anna
- Published
- 2022
- Full Text
- View/download PDF
13. Persistence of immunogenicity after seven COVID-19 vaccines given as third dose boosters following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK: Three month analyses of the COV-BOOST trial.
- Author
-
Liu, Xinxue, Munro, Alasdair P S, Feng, Shuo, Janani, Leila, Aley, Parvinder K, Babbage, Gavin, Baxter, David, Bula, Marcin, Cathie, Katrina, Chatterjee, Krishna, Dejnirattisai, Wanwisa, Dodd, Kate, Enever, Yvanne, Qureshi, Ehsaan, Goodman, Anna L., Green, Christopher A, Harndahl, Linda, Haughney, John, Hicks, Alexander, van der Klaauw, Agatha A., Kwok, Jonathan, Libri, Vincenzo, Llewelyn, Martin J, McGregor, Alastair C, Minassian, Angela M., Moore, Patrick, Mughal, Mehmood, Mujadidi, Yama F, Holliday, Kyra, Osanlou, Orod, Osanlou, Rostam, Owens, Daniel R, Pacurar, Mihaela, Palfreeman, Adrian, Pan, Daniel, Rampling, Tommy, Regan, Karen, Saich, Stephen, Serafimova, Teona, Saralaya, Dinesh, Screaton, Gavin R, Sharma, Sunil, Sheridan, Ray, Sturdy, Ann, Supasa, Piyada, Thomson, Emma C, Todd, Shirley, Twelves, Chris, Read, Robert C., Charlton, Sue, Hallis, Bassam, Ramsay, Mary, Andrews, Nick, Lambe, Teresa, Nguyen-Van-Tam, Jonathan S, Cornelius, Victoria, Snape, Matthew D, and Faust, Saul N
- Published
- 2022
- Full Text
- View/download PDF
14. Immunogenicity, safety, and reactogenicity of heterologous COVID-19 primary vaccination incorporating mRNA, viral-vector, and protein-adjuvant vaccines in the UK (Com-COV2): a single-blind, randomised, phase 2, non-inferiority trial
- Author
-
Stuart, Arabella S V, Shaw, Robert H, Liu, Xinxue, Greenland, Melanie, Aley, Parvinder K, Andrews, Nick J, Cameron, J C, Charlton, Sue, Clutterbuck, Elizabeth A, Collins, Andrea M, Darton, Tom, Dinesh, Tanya, Duncan, Christopher J A, England, Anna, Faust, Saul N, Ferreira, Daniela M, Finn, Adam, Goodman, Anna L, Green, Christopher A, Hallis, Bassam, Heath, Paul T, Hill, Helen, Horsington, Bryn M, Lambe, Teresa, Lazarus, Rajeka, Libri, Vincenzo, Lillie, Patrick J, Mujadidi, Yama F, Payne, Ruth, Plested, Emma L, Provstgaard-Morys, Samuel, Ramasamy, Maheshi N, Ramsay, Mary, Read, Robert C, Robinson, Hannah, Screaton, Gavin R, Singh, Nisha, Turner, David P J, Turner, Paul J, Vichos, Iason, White, Rachel, Nguyen-Van-Tam, Jonathan S, and Snape, Matthew D
- Published
- 2022
- Full Text
- View/download PDF
15. Distinct early cellular kinetics in participants protected against colonization upon Bordetella pertussis challenge
- Author
-
Diks, Annieck M., Graaf, Hans de, Teodosio, Cristina, Groenland, Rick J., Mooij, Bas de, Ibrahim, Muktar, Hill, Alison R., Read, Robert C., van Dongen, Jacques J.M., and Berkowska, Magdalena A.
- Subjects
Pertussis vaccines -- Physiological aspects ,Vaccination -- Models -- Physiological aspects ,Immune response -- Health aspects -- Physiological aspects ,Whooping-cough -- Physiological aspects -- Models -- Prevention ,Health care industry - Abstract
BACKGROUND. To date, only limited data are available on the mechanisms of protection against colonization with Bordetella pertussis in humans. METHODS. In this study, the cellular responses to B. pertussis challenge were monitored longitudinally using high- dimensional EuroFlow-based flow cytometry, allowing quantitative detection of more than 250 different immune cell subsets in the blood of 15 healthy donors. RESULTS. Participants who were protected against colonization showed different early cellular responses compared with colonized participants. Especially prominent for colonization-protected participants were the early expansion of CD36nonclassical monocytes on day 1 (D1), natural killer cells (D3), follicular T helper cells (D1-D3), and plasma cells (D3). Plasma cell expansion on D3 correlated negatively with the CFU load on D7 and D9 after challenge. Increased plasma cell maturation on D11-D14 was found in participants with seroconversion. CONCLUSION. These early cellular immune responses following experimental infection can now be further characterized and potentially linked to an efficient mucosal immune response, preventing colonization. Ultimately, their presence may be used to evaluate whether new B. pertussis vaccine candidates are protective against B. pertussis colonization, e.g., by bacterial challenge after vaccination. TRIAL REGISTRATION. ClinicalTrials.gov NCT03751514. FUNDING. Innovative Medicines Initiative 2 Joint Undertaking and the EuroFlow Consortium., Introduction The introduction of vaccines has significantly reduced the amount of infectious disease-related deaths (1). However, vaccine-induced protection is often based on empirical results, and the mechanisms of protection and [...]
- Published
- 2023
- Full Text
- View/download PDF
16. Safety and immunogenicity of seven COVID-19 vaccines as a third dose (booster) following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK (COV-BOOST): a blinded, multicentre, randomised, controlled, phase 2 trial
- Author
-
Riordan, Andrew, Ustianowski, Andrew, Rogers, Chris A, Hughes, Stephen, Longshaw, Laura, Stockport, Jane, Hughes, Rachel, Grundy, Lynne, Tudor Jones, Lona, Guha, Arpan, Snashall, Emma, Eadsforth, Tom, Reeder, Sally, Storton, Kim, Munusamy, Malathi, Tandy, Bridget, Egbo, Akamino, Cox, Stephen, Ahmed, Nabeela Nazir, Shenoy, Anil, Bousfield, Rachel, Wixted, Donna, Gutteridge, Helen, Mansfield, Becky, Herbert, Christopher, Holliday, Kyra, Calderwood, James, Barker, Dominique, Brandon, Jacqueline, Tulloch, Hayley, Colquhoun, Suzie, Thorp, Helen, Radford, Helen, Evans, Julie, Baker, Helena, Thorpe, Jeanette, Batham, Sally, Hailstone, Jessica, Phillips, Rachael, Kumar, Dileep, Westwell, Fran, Makia, Fiona, Hopkins, NinaSimone, Barcella, Lara, Mpelembue, Mushiya, dabagh, Maja, lang, Matilda, khan, Farida, Adebambo, Olumide, Chita, Sunder, Corrah, Tumena, Whittington, Ashley, John, Laurence, Roche, Siobhan, Wagstaff, Lynda, Farrier, Adam, Bisnauthsing, Karen, Serafimova, Teona, Nanino, Elisa, Cooney, Enya, Wilson-Goldsmith, Jaimie, Nguyen, Hanna, Mazzella, Andrea, Jackson, Beth, Aslam, Suahil, Bawa, Tanveer, Broadhead, Samantha, Farooqi, Sadaf, Piper, Jo, Weighell, Rowena, Pickup, Lorinda, Shamtally, Djamila, Domingo, Jason, Kourampa, Evgenia, Hale, Colin, Gibney, Jennifer, Stackpoole, Michael, Rashid-Gardner, Zalina, Lyon, Rebecca, McDonnell, Chloe, Cole, Christine, Stewart, Anna, McMillan, Gillian, Savage, Mary, Beckett, Helen, Moorbey, Chantelle, Desai, Amisha, Brown, Claire, Naker, Kush, Qureshi, Ehsaan, Trinham, Charlotte, Sabine, Charlotte, Moore, Sophie, Hurdover, Steve, Justice, Edwin, Smith, David, Plested, Emma, Ferreira Da Silva, Carla, White, Rachel, Robinson, Hannah, Cifuentes, Liliana, Morshead, Gertraud, Drake-Brockman, Rachael, Kinch, Patrick, Kasanyinga, Mwila, Clutterbuck, Elizabeth A., Bibi, Sagida, Stuart, Arabella SV, Shaw, Robert H, Singh, Michael, Champaneri, Trishna, Irwin, Margaret, Khan, Mohammed, Kownacka, Alicja, Nabunjo, Martha, Osuji, Carool, Hladkiwskyj, John, Galvin, Dominic, Patel, Gita, Mouland, Johanna, Longhurst, Beverley, Moon, Maria, Giddins, Beth, Pereira Dias Alves, Carlota, Richmond, Leah, Minnis, Christine, Baryschpolec, Sonia, Elliott, Scott, Fox, Lauren, Graham, Victoria, Baker, Natalie, Godwin, Kerry, Buttigieg, Karren, Knight, Chanice, Brown, Phillip, Lall, Paminder, Shaik, Imam, Chiplin, Emily, Brunt, Emily, Leung, Stephanie, Allen, Lauren, Thomas, Steve, Fraser, Sara, Choi, Bea, Gouriet, Jade, Freedman, Andrew, Perkins, Jonathan, Gowland, Andrew, Macdonald, Jonathan, Seenan, John Paul, Starinskij, Igor, Seaton, Andrew, Peters, Erica, Singh, Stephen, Gardside, Ben, Bonnaud, Avril, Davies, Ceri, Gordon, Elizabeth, Keenan, Samantha, Hall, Jane, Wilkins, Suzanne, Tasker, Suzanne, James, Rob, Seath, Ingrid, Littlewood, Kelly, Newman, Joseph, Boubriak, Iryna, Suggitt, Debbie, Haydock, Helen, Bennett, Sara, Woodyatt, Wiesia, Hughes, Kerry, Bell, Judith, Coughlan, Tricia, van Welsenes, Donald, Kamal, Mohammed, Cooper, Chris, Tunstall, Simon, Ronan, Nicholas, Cutts, Rebecca, Dare, Tracey, Yim, Yee Ting Nicole, Whittley, Sarah, Ricamara, Marivic, Hamal, Shama, Adams, Kirsty, Baker, Holly, Driver, Kimberley, Turner, Nicola, Rawlins, Todd, Roy, Subarna, Merida-Morillas, Marta, Sakagami, Yukari, Andrews, Antonette, Goncalves cordeiro, Lillian, Stokes, Matthew, Ambihapathy, Wythehi, Spencer, Joanne, Parungao, Nina, Berry, Lisa, Cullinane, James, Presland, Laura, Ross-Russell, Amy, Warren, Sarah, Baker, Jonathan, Oliver, Abigail, Buadi, Amanda, Lee, Kim, Haskell, Louise, Romani, Rossana, Bentley, Ian, Whitbred, Tim, Fowler, Simon, Gavin, John, Magee, Alan, Watson, Tara, Nightingale, Kari, Marius, Phedra, Summerton, Eloise, Locke, Emily, Honey, Thomas, Lingwood, Aidan, de la Haye, Anastasia, Elliott, Ryan Stephen, Underwood, Karen, King, Mikayala, Davies-Dear, Sharon, Horsfall, Emily, Chalwin, Olivia, Burton, Holly, Edwards, Christopher J, Welham, Benjamin, Garrahy, Sarah, Hall, Fran, Ladikou, Eleni, Mullan, Dee, Hansen, Daniel, Campbell, Marion, Dos Santos, Filipa, Habash-Bailey, Haniah, Lakeman, Nicki, Branney, Debbie, Vamplew, Luke, Hogan, Alison, Frankham, Jorden, Wiselka, Martin, Vail, Dennyl, Wenn, Victoria, Renals, Valerie, Ellis, Kate, Lewis-Taylor, Jessica, Magan, Javier, Hardy, Anna, Appleby, Kim, Munro, Alasdair P S, Janani, Leila, Cornelius, Victoria, Aley, Parvinder K, Babbage, Gavin, Baxter, David, Bula, Marcin, Cathie, Katrina, Chatterjee, Krishna, Dodd, Kate, Enever, Yvanne, Gokani, Karishma, Goodman, Anna L, Green, Christopher A, Harndahl, Linda, Haughney, John, Hicks, Alexander, van der Klaauw, Agatha A, Kwok, Jonathan, Lambe, Teresa, Libri, Vincenzo, Llewelyn, Martin J, McGregor, Alastair C, Minassian, Angela M, Moore, Patrick, Mughal, Mehmood, Mujadidi, Yama F, Murira, Jennifer, Osanlou, Orod, Osanlou, Rostam, Owens, Daniel R, Pacurar, Mihaela, Palfreeman, Adrian, Pan, Daniel, Rampling, Tommy, Regan, Karen, Saich, Stephen, Salkeld, Jo, Saralaya, Dinesh, Sharma, Sunil, Sheridan, Ray, Sturdy, Ann, Thomson, Emma C, Todd, Shirley, Twelves, Chris, Read, Robert C, Charlton, Sue, Hallis, Bassam, Ramsay, Mary, Andrews, Nick, Nguyen-Van-Tam, Jonathan S, Snape, Matthew D, Liu, Xinxue, and Faust, Saul N
- Published
- 2021
- Full Text
- View/download PDF
17. Foreword
- Author
-
Read, Robert C., primary
- Published
- 2022
- Full Text
- View/download PDF
18. Antibiotics for lower respiratory tract infection in children presenting in primary care in England (ARTIC PC): a double-blind, randomised, placebo-controlled trial
- Author
-
Little, Paul, Francis, Nick A, Stuart, Beth, O'Reilly, Gilly, Thompson, Natalie, Becque, Taeko, Hay, Alastair D, Wang, Kay, Sharland, Michael, Harnden, Anthony, Yao, Guiqing, Raftery, James, Zhu, Shihua, Little, Joseph, Hookham, Charlotte, Rowley, Kate, Euden, Joanne, Harman, Kim, Coenen, Samuel, Read, Robert C, Woods, Catherine, Butler, Christopher C, Faust, Saul N, Leydon, Geraldine, Wan, Mandy, Hood, Kerenza, Whitehurst, Jane, Richards-Hall, Samantha, Smith, Peter, Thomas, Michael, Moore, Michael, and Verheij, Theo
- Published
- 2021
- Full Text
- View/download PDF
19. Safety and immunogenicity of heterologous versus homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine (Com-COV): a single-blind, randomised, non-inferiority trial
- Author
-
Munro, Alasdair P S, Bartholomew, Jazz, Presland, Laura, Horswill, Sarah, Warren, Sarah, Varkonyi-Clifford, Sophie, Saich, Stephen, Adams, Kirsty, Ricamara, Marivic, Turner, Nicola, Yee Ting, Nicole Y, Whittley, Sarah, Rampling, Tommy, Desai, Amisha, Brown, Claire H, Qureshi, Ehsaan, Gokani, Karishma, Naker, Kush, Kellett Wright, Johanna K, Williams, Rachel L, Riaz, Tawassal, Penciu, Florentina D, Di Maso, Claudio, Howe, Elizabeth G, Vichos, Iason, Ghulam Farooq, Mujtaba, Noristani, Rabiullah, Yao, Xin L, Oldfield, Neil J, Hammersley, Daniel, Belton, Sue, Royal, Simon, San Francisco Ramos, Alberto, Hultin, Cecilia, Galiza, Eva P, Shiham, Farah, Solórzano, Carla, Sainsbury, Hannah, Davies, Kelly, Ambrose, Pauline, Hitchins, Lisa, Baker, Natalie, Leung, Stephanie, Fothergill, Ross, Godwin, Kerry, Buttigieg, Karen, Shaik, Imam, Brown, Phill, Knight, Chanice, Lall, Paminder, Allen, Lauren, Liu, Xinxue, Shaw, Robert H, Stuart, Arabella S V, Greenland, Melanie, Aley, Parvinder K, Andrews, Nick J, Cameron, J Claire, Charlton, Sue, Clutterbuck, Elizabeth A, Collins, Andrea M, Dinesh, Tanya, England, Anna, Faust, Saul N, Ferreira, Daniela M, Finn, Adam, Green, Christopher A, Hallis, Bassam, Heath, Paul T, Hill, Helen, Lambe, Teresa, Lazarus, Rajeka, Libri, Vincenzo, Long, Fei, Mujadidi, Yama F, Plested, Emma L, Provstgaard-Morys, Samuel, Ramasamy, Maheshi N, Ramsay, Mary, Read, Robert C, Robinson, Hannah, Singh, Nisha, Turner, David P J, Turner, Paul J, Walker, Laura L, White, Rachel, Nguyen-Van-Tam, Jonathan S, and Snape, Matthew D
- Published
- 2021
- Full Text
- View/download PDF
20. Qualitative interview study exploring the perspectives of pregnant women on participating in controlled human infection research in the UK
- Author
-
Dorey, Robert B, primary, Theodosiou, Anastasia A, additional, Read, Robert C, additional, Vandrevala, Tushna, additional, and Jones, Christine E, additional
- Published
- 2023
- Full Text
- View/download PDF
21. Reducing risks from coronavirus transmission in the home—the role of viral load
- Author
-
Little, Paul, Read, Robert C, Amlôt, Richard, Chadborn, Tim, Rice, Cathy, Bostock, Jennifer, and Yardley, Lucy
- Published
- 2020
22. Neisseria lactamica Controlled Human Infection Model
- Author
-
Dale, Adam P., primary, Gbesemete, Diane F., additional, Read, Robert C., additional, and Laver, Jay R., additional
- Published
- 2021
- Full Text
- View/download PDF
23. A new era of Open Access for the Journal of Infection
- Author
-
Read, Robert C, primary and Partridge, David G, additional
- Published
- 2023
- Full Text
- View/download PDF
24. Persistence of immune response in heterologous COVID vaccination schedules in the Com-COV2 study – A single-blind, randomised trial incorporating mRNA, viral-vector and protein-adjuvant vaccines
- Author
-
Shaw, Robert H., primary, Greenland, Melanie, additional, Stuart, Arabella S.V., additional, Aley, Parvinder K., additional, Andrews, Nick J., additional, Cameron, J. Claire, additional, Charlton, Sue, additional, Clutterbuck, Elizabeth A., additional, Collins, Andrea M., additional, Darton, Tom, additional, Dinesh, Tanya, additional, Duncan, Christopher J.A., additional, Faust, Saul N., additional, Ferreira, Daniela M., additional, Finn, Adam, additional, Goodman, Anna L., additional, Green, Christopher A., additional, Hallis, Bassam, additional, Heath, Paul T., additional, Hill, Helen, additional, Lambe, Teresa, additional, Libri, Vincenzo, additional, Lillie, Patrick J., additional, Morey, Ella, additional, Mujadidi, Yama F., additional, Payne, Ruth, additional, Plested, Emma L., additional, Provstgaard-Morys, Samuel, additional, Ramasamy, Maheshi N., additional, Ramsay, Mary, additional, Read, Robert C., additional, Robinson, Hannah, additional, Screaton, Gavin R., additional, Singh, Nisha, additional, Turner, David P.J., additional, Turner, Paul J., additional, White, Rachel, additional, Nguyen-Van-Tam, Jonathan S., additional, Liu, Xinxue, additional, and Snape, Matthew D., additional
- Published
- 2023
- Full Text
- View/download PDF
25. Genetic Polymorphism of the Binding Domain of Surfactant Protein-A2 Increases Susceptibility to Meningococcal Disease
- Author
-
Read, Robert C.
- Published
- 2006
26. The infant pharyngeal microbiomes: origin, impact and manipulation
- Author
-
Theodosiou, Anastasia A., Dorey, Robert B., Read, Robert C., and Jones, Christine E.
- Published
- 2020
- Full Text
- View/download PDF
27. Corrigendum to “Persistence of immunogenicity after seven COVID-19 vaccines given as third dose boosters following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK: Three month analyses of the COV-BOOST trial” [J Infect 84(6) (2022) 795–813, 5511]
- Author
-
Liu, Xinxue, primary, Munro, Alasdair PS, additional, Feng, Shuo, additional, Janani, Leila, additional, Aley, Parvinder K, additional, Babbage, Gavin, additional, Baxter, David, additional, Bula, Marcin, additional, Cathie, Katrina, additional, Chatterjee, Krishna, additional, Dejnirattisai, Wanwisa, additional, Dodd, Kate, additional, Enever, Yvanne, additional, Qureshi, Ehsaan, additional, Goodman, Anna L., additional, Green, Christopher A, additional, Harndahl, Linda, additional, Haughney, John, additional, Hicks, Alexander, additional, van der Klaauw, Agatha A., additional, Kwok, Jonathan, additional, Libri, Vincenzo, additional, Llewelyn, Martin J, additional, McGregor, Alastair C, additional, Minassian, Angela M., additional, Moore, Patrick, additional, Mughal, Mehmood, additional, Mujadidi, Yama F, additional, Holliday, Kyra, additional, Osanlou, Orod, additional, Osanlou, Rostam, additional, Owens, Daniel R, additional, Pacurar, Mihaela, additional, Palfreeman, Adrian, additional, Pan, Daniel, additional, Rampling, Tommy, additional, Regan, Karen, additional, Saich, Stephen, additional, Serafimova, Teona, additional, Saralaya, Dinesh, additional, Screaton, Gavin R, additional, Sharma, Sunil, additional, Sheridan, Ray, additional, Sturdy, Ann, additional, Supasa, Piyada, additional, Thomson, Emma C, additional, Todd, Shirley, additional, Twelves, Chris, additional, Read, Robert C., additional, Charlton, Sue, additional, Hallis, Bassam, additional, Ramsay, Mary, additional, Andrews, Nick, additional, Lambe, Teresa, additional, Nguyen-Van-Tam, Jonathan S, additional, Cornelius, Victoria, additional, Snape, Matthew D, additional, and Faust, Saul N, additional
- Published
- 2023
- Full Text
- View/download PDF
28. A phase III observer-blind randomized, controlled study to evaluate the immune response and the correlation with nasopharyngeal carriage after immunization of university students with a quadrivalent meningococcal ACWY glycoconjugate or serogroup B meningococcal vaccine
- Author
-
Read, Robert C., Dull, Peter, Bai, Xilian, Nolan, Kate, Findlow, Jamie, Bazaz, Rohit, Kleinschmidt, Annett, McCarthy, Maggie, Wang, Huajun, Toneatto, Daniela, and Borrow, Ray
- Published
- 2017
- Full Text
- View/download PDF
29. A Lipopolysaccharide-Deficient Mutant of Neisseria meningitidis Elicits Attenuated Cytokine Release by Human Macrophages and Signals via Toll-like Receptor (TLR) 2 but Not via TLR4/MD2
- Author
-
Pridmore, Alison C., Wyllie, David H., Abdillahi, Fatumo, Steeghs, Liana, van der Ley, Peter, Dower, Steven K., and Read, Robert C.
- Published
- 2001
30. Bacterial Meningitis in Malawian Adults: Pneumococcal Disease Is Common, Severe, and Seasonal
- Author
-
Gordon, Stephen B. and Read, Robert C.
- Published
- 2000
31. Neisseria meningitidis and meningococcal disease: recent discoveries and innovations
- Author
-
Read, Robert C.
- Published
- 2019
- Full Text
- View/download PDF
32. The nonpathogenic commensal Neisseria: friends and foes in infectious disease
- Author
-
Dorey, Robert B., Theodosiou, Anastasia A., Read, Robert C., and Jones, Christine E.
- Published
- 2019
- Full Text
- View/download PDF
33. Distinct early cellular kinetics in participants protected from colonization upon Bordetella pertussis challenge
- Author
-
Diks, Annieck M., primary, de Graaf, Hans, additional, Teodosio, Cristina, additional, Groenland, Rick J., additional, de Mooij, Bas, additional, Ibrahim, Muktar, additional, Hill, Alison R., additional, Read, Robert C., additional, van Dongen, Jacques J.M., additional, and Berkowska, Magdalena A., additional
- Published
- 2023
- Full Text
- View/download PDF
34. Effect of colonisation with Neisseria lactamica on cross-reactive anti-meningococcal B-cell responses: a randomised, controlled, human infection trial
- Author
-
Dale, Adam P, primary, Theodosiou, Anastasia A, additional, Gbesemete, Diane F, additional, Guy, Jonathan M, additional, Jones, Eleanor F, additional, Hill, Alison R, additional, Ibrahim, Muktar M, additional, de Graaf, Hans, additional, Ahmed, Muhammad, additional, Faust, Saul N, additional, Gorringe, Andrew R, additional, Polak, Marta E, additional, Laver, Jay R, additional, and Read, Robert C, additional
- Published
- 2022
- Full Text
- View/download PDF
35. Analysis of histone post translational modifications in primary monocyte derived macrophages using reverse phase × reverse phase chromatography in conjunction with porous graphitic carbon stationary phase
- Author
-
Minshull, Thomas C., Cole, Joby, Dockrell, David H., Read, Robert C., and Dickman, Mark J.
- Published
- 2016
- Full Text
- View/download PDF
36. The environmental deposition of influenza virus from patients infected with influenza A(H1N1)pdm09: Implications for infection prevention and control
- Author
-
Killingley, Benjamin, Greatorex, Jane, Digard, Paul, Wise, Helen, Garcia, Fayna, Varsani, Harsha, Cauchemez, Simon, Enstone, Joanne E., Hayward, Andrew, Curran, Martin D., Read, Robert C., Lim, Wei S., Nicholson, Karl G., and Nguyen-Van-Tam, Jonathan S.
- Published
- 2016
- Full Text
- View/download PDF
37. Microevolution of Neisseria lactamica during nasopharyngeal colonisation induced by controlled human infection
- Author
-
Pandey, Anish, Cleary, David W., Laver, Jay R., Gorringe, Andrew, Deasy, Alice M., Dale, Adam P., Morris, Paul D., Didelot, Xavier, Maiden, Martin C. J., and Read, Robert C.
- Published
- 2018
- Full Text
- View/download PDF
38. Effect of priming interval on reactogenicity, peak immunological response, and waning after homologous and heterologous COVID-19 vaccine schedules: exploratory analyses of Com-COV, a randomised control trial
- Author
-
Shaw, Robert H, primary, Liu, Xinxue, additional, Stuart, Arabella S V, additional, Greenland, Melanie, additional, Aley, Parvinder K, additional, Andrews, Nick J, additional, Cameron, J Claire, additional, Charlton, Sue, additional, Clutterbuck, Elizabeth A, additional, Collins, Andrea M, additional, Dejnirattisai, Wanwisa, additional, Dinesh, Tanya, additional, Faust, Saul N, additional, Ferreira, Daniela M, additional, Finn, Adam, additional, Green, Christopher A, additional, Hallis, Bassam, additional, Heath, Paul T, additional, Hill, Helen, additional, Lambe, Teresa, additional, Lazarus, Rajeka, additional, Libri, Vincenzo, additional, Long, Fei, additional, Mujadidi, Yama F, additional, Plested, Emma L, additional, Morey, Ella R, additional, Provstgaard-Morys, Samuel, additional, Ramasamy, Maheshi N, additional, Ramsay, Mary, additional, Read, Robert C, additional, Robinson, Hannah, additional, Screaton, Gavin R, additional, Singh, Nisha, additional, Turner, David P J, additional, Turner, Paul J, additional, Vichos, Iason, additional, Walker, Laura L, additional, White, Rachel, additional, Nguyen-Van-Tam, Jonathan S, additional, Snape, Matthew D, additional, Munro, Alasdair P.S., additional, Bartholomew, Jazz, additional, Presland, Laura, additional, Horswill, Sarah, additional, Warren, Sarah, additional, Varkonyi-Clifford, Sophie, additional, Saich, Stephen, additional, Adams, Kirsty, additional, Ricamara, Marivic, additional, Turner, Nicola, additional, Yee Ting, Nicole Y., additional, Whittley, Sarah, additional, Rampling, Tommy, additional, Desai, Amisha, additional, Brown, Claire H., additional, Qureshi, Ehsaan, additional, Gokani, Karishma, additional, Naker, Kush, additional, Kellett Wright, Johanna K., additional, Williams, Rachel L., additional, Riaz, Tawassal, additional, Penciu, Florentina D., additional, Carson, Amy, additional, Di Maso, Claudio, additional, Mead, Gracie, additional, Howe, Elizabeth G., additional, Ghulam Farooq, Mujtaba, additional, Noristani, Rabiullah, additional, Yao, Xin L., additional, Oldfield, Neil J., additional, Hammersley, Daniel, additional, Belton, Sue, additional, Royal, Simon, additional, San Francisco Ramos, Alberto, additional, Hultin, Cecilia, additional, Galiza, Eva P., additional, Crook, Rebecca, additional, Bula, Marcin, additional, Fyles, Fred, additional, Burhan, Hassan, additional, Maelin, Flora, additional, Hughes, Elen, additional, and Okenyi, Emmanuel, additional
- Published
- 2022
- Full Text
- View/download PDF
39. Nasal Inoculation of the Commensal Neisseria lactamica Inhibits Carriage of Neisseria meningitidis by Young Adults: A Controlled Human Infection Study
- Author
-
Deasy, Alice M., Guccione, Ed, Dale, Adam P., Andrews, Nick, Evans, Cariad M., Bennett, Julia S., Bratcher, Holly B., Maiden, Martin C. J., Gorringe, Andrew R., and Read, Robert C.
- Published
- 2015
40. Effect of a quadrivalent meningococcal ACWY glycoconjugate or a serogroup B meningococcal vaccine on meningococcal carriage: an observer-blind, phase 3 randomised clinical trial
- Author
-
Read, Robert C, Baxter, David, Chadwick, David R, Faust, Saul N, Finn, Adam, Gordon, Stephen B, Heath, Paul T, Lewis, David J M, Pollard, Andrew J, Turner, David P J, Bazaz, Rohit, Ganguli, Amitava, Havelock, Tom, Neal, Keith R, Okike, Ifeanyichukwu O, Morales-Aza, Begonia, Patel, Kamlesh, Snape, Matthew D, Williams, John, Gilchrist, Stefanie, Gray, Steve J, Maiden, Martin C J, Toneatto, Daniela, Wang, Huajun, McCarthy, Maggie, Dull, Peter M, and Borrow, Ray
- Published
- 2014
- Full Text
- View/download PDF
41. Nocardiosis and actinomycosis
- Author
-
Simpson, Ruan S. and Read, Robert C.
- Published
- 2014
- Full Text
- View/download PDF
42. Orocervical Infection
- Author
-
Read, Robert C., primary
- Published
- 2017
- Full Text
- View/download PDF
43. List of Contributors
- Author
-
Abrahamian, Fredrick M., primary, Aldape, Michael J., additional, Aldasoro, Edelweiss, additional, Allen, Upton D., additional, Al-Sum, Hythem, additional, Anadkat, Milan J., additional, Anders, Katherine, additional, Angelakis, Emmanouil, additional, Angus, Brian John, additional, Antoniadou, Anastasia, additional, Arena, Fabio, additional, Arends, Joop E., additional, Arribas, Jose R., additional, Artenstein, Andrew W., additional, Atherton, John C., additional, Aucott, John N., additional, Aw, Tar-Ching, additional, Babcock, Hilary M., additional, Bailey, Robin, additional, Bailey, Thomas C., additional, Banks, Adam Z., additional, Barillo, David J., additional, Barrette, Ernie-Paul, additional, Bauer, Martijn P., additional, Bayston, Roger, additional, Beard, C. Ben, additional, Beardsley, Justin, additional, Beeching, Nick J., additional, Bégué, Rodolfo E., additional, Beldi, Guido, additional, Benson, Constance A., additional, Berbari, Elie F., additional, Berenger, Jean-Michel, additional, Berger, Christoph, additional, Bernardino, Jose I., additional, Bille, Jacques, additional, Billioux, Alexander C., additional, Bitnun, Ari, additional, Blair, Iain, additional, Blanche, Stéphane, additional, Bleck, Thomas P., additional, Bleeker-Rovers, Chantal P., additional, Bleijenberg, Gijs, additional, Bloch, Karen C., additional, Blum, Johannes, additional, Blumberg, Emily A., additional, Bonomo, Robert A., additional, Bonten, Marc J.M., additional, Bourayou, Rafik, additional, Bouza, Emilio, additional, Brandt, K. Ashley, additional, Bretelle, Florence, additional, Brisse, Sylvain, additional, Britton, Warwick J., additional, Brook, Itzhak, additional, Brouwer, Matthijs C., additional, Browne, Sarah K., additional, Bryant, Amy E., additional, Bühler, Silja, additional, Bulger, Eileen M., additional, Buller, R. Mark L., additional, Burke, Leah A., additional, Burri, Christian, additional, Butler, Marcus W., additional, Calandra, Thierry, additional, Calfee, David P., additional, Calvo-Cano, Antonia, additional, Cameron, D. William, additional, Carcillo, Joseph A., additional, Carson, Gail, additional, Chambers, Stephen T., additional, Charrel, Remi N., additional, Nguyen, Vinh Chau Van, additional, Chevaliez, Stéphane, additional, Chiller, Tom M., additional, Christaki, Eirini, additional, Chung, Kevin K., additional, Clifford, David B., additional, Clumeck, Nathan, additional, Cohen, Jonathan, additional, Collinge, John, additional, Conlon, Christopher P., additional, Conrad, Curdin, additional, Cooke, Fiona J., additional, Cope, Jennifer Rittenhouse, additional, Corey, G. Ralph, additional, Cross, John H., additional, Cunha, Burke A., additional, Cunha, Cheston B., additional, D'Journo, Benoit, additional, Daikos, George L., additional, Daniels, Johannes M.A., additional, Davidson, Robert N., additional, Day, Nicholas P.J., additional, De Cock, Kevin M., additional, de Silva, Thushan I., additional, de Vries, Henry J.C., additional, de Wit, Stéphane, additional, Delaloye, Julie, additional, Denning, David W., additional, Dennis, David T., additional, Dhanireddy, Shireesha, additional, Dielubanza, Elodi J., additional, Diemert, David J., additional, Doganay, Mehmet, additional, Doherty, Tom, additional, Dolecek, Christiane, additional, Dondorp, Arjen M., additional, Douglas, Abby, additional, Drancourt, Michel, additional, Dubourg, Grégory, additional, Dudley, Michael N., additional, Durand, Guillaume, additional, Eckhardt, Benjamin J., additional, Efstratiou, Androulla, additional, Ekkelenkamp, Miquel B., additional, Eranki, Ambika, additional, Erdem, Hakan, additional, Escota, Gerome V., additional, Evans, Heather L., additional, Eziefula, Alice Chijioke, additional, Fenollar, Florence, additional, Fenwick, Alan, additional, Fierer, Joshua, additional, Finch, Roger G., additional, Fleckenstein, James M., additional, Forstner, Christina, additional, Foschi, Federico, additional, Fournier, Pierre-Edouard, additional, French, Martyn A., additional, Gage, Kenneth L., additional, Garcia, Lynne S., additional, Gascon, Joaquim, additional, Gastañaduy, Arturo S., additional, Gautret, Philippe, additional, Geisler, William M., additional, Ghanem, Khalil G., additional, Giani, Tommaso, additional, Giannella, Maddalena, additional, Gilliam, Bruce L., additional, Gilliet, Michel, additional, Glaser, Carol A., additional, Glupczynski, Youri, additional, Gnann, John W., additional, Goldstein, Ellie J.C., additional, Gottstein, Bruno, additional, Gouriet, Frederique, additional, Gravitt, Patti E., additional, Green, Michael D., additional, Green, Stephen T., additional, Groll, Andreas H., additional, Gulick, Roy M., additional, Gupta, Arjun, additional, Habib, Gilbert, additional, Harbarth, Stephan, additional, Harris, Marianne, additional, Hayden, Frederick G., additional, Hetem, David J., additional, Hill, Philip C., additional, Hirschel, Bernard, additional, Hodowanec, Aimee C., additional, Hoffart, Louis, additional, Hoffmann, Christian, additional, Holland, Steven M., additional, Horby, Peter W., additional, Horne, David J., additional, Hraiech, Sami, additional, Hull, Mark W., additional, Huttner, Angela, additional, Ingram, Richard J.M., additional, Islam, Jasmin, additional, Ison, Michael G., additional, James, Scott H., additional, Jenkins, Claire, additional, Jenkins, Stephen G., additional, Jensen, Jørgen Skov, additional, Johnston, Christine, additional, Jones, Theodore B., additional, Jordan, Stephen J., additional, Julian, Kathleen G., additional, Kato, Yasuyuki, additional, Kauffman, Carol A., additional, Kaye, Keith S., additional, Keane, Michael P., additional, Keeney, James, additional, Kelly, Paul, additional, Kent, Stephen J., additional, Kern, Winfried V., additional, Keynan, Yoav, additional, Kim, Andrea A., additional, Koné-Paut, Isabelle, additional, Kosmidis, Chris, additional, Kroes, Aloys C.M., additional, Kroon, Frank P., additional, Ksiazek, Thomas G., additional, Kuhlmann, F. Matthew, additional, Kuijper, Ed J., additional, Kwon, Jennie H., additional, Kyei, George B., additional, Lacombe, Karine, additional, Lagacé-Wiens, Philippe, additional, Lagier, Jean-Christophe, additional, Lamagni, Theresa, additional, Landraud, Luce, additional, Lanternier, Fanny, additional, LaPlante, Kerry L., additional, Lawn, Stephen D., additional, Lawrence, Steven J., additional, Leblebicioglu, Hakan, additional, Lee, Nelson, additional, Leggett, James E., additional, Lehours, Philippe, additional, Levy, Pierre-Yves, additional, Leyh, Rainer G., additional, Lillis, Rebecca A., additional, Limmathurotsakul, Direk, additional, Lin, Jennifer, additional, Lindquist, H.D. Alan, additional, Lipsky, Benjamin A., additional, Liscynesky, Christina, additional, Looney, David, additional, Lortholary, Olivier, additional, Lowy, Franklin D., additional, Luft, Benjamin J., additional, Mackowiak, Philip A., additional, MacPherson, Paul A., additional, Maghraoui-Slim, Valérie, additional, Mallon, Patrick W., additional, Mangino, Julie E., additional, Manuel, Oriol, additional, Marchetti, Oscar, additional, Marks, Kristen M., additional, Marr, Kieren A., additional, Marrazzo, Jeanne, additional, Marschall, Jonas, additional, Martin, David H., additional, Matonti, Frédéric, additional, Matulewicz, Richard S., additional, Mayer, Kenneth H., additional, McCulloh, Russell J., additional, McGready, Rose, additional, Mdodo, Rennatus, additional, Mead, Simon, additional, Mégraud, Francis, additional, Meintjes, Graeme, additional, Metcalf, Sarah C., additional, Michaels, Marian G., additional, Migliori, Giovanni Battista, additional, Miles, Michael A., additional, Miller, Alastair, additional, Mimiaga, Matthew J., additional, Mingeot-Leclercq, Marie-Paule, additional, Misch, Elizabeth Ann, additional, Mitreva, Makedonka, additional, Montaner, Julio S.G., additional, Moore, Caroline B., additional, Muñoz, Patricia, additional, Muñoz, Jose, additional, Murray, Clinton K., additional, Musso, Didier, additional, Mutengo, Mable, additional, Mutizwa, Misha M., additional, Naber, Kurt G., additional, Natarajan, Pavithra, additional, Neme, Santiago, additional, Newton, Paul N., additional, Nichols, Ronald A., additional, Nicolle, Lindsay E., additional, Nosten, François, additional, Notarangelo, Luigi D., additional, Nutman, Thomas B., additional, Nyirjesy, Paul, additional, O'Connell, P. Ronan, additional, Opal, Steven M., additional, Ormerod, L. Peter, additional, Osmon, Douglas R., additional, Pankert, Marie Boulze, additional, Pantaleo, Giuseppe, additional, Papazian, Laurent, additional, Parente, Diane M., additional, Parola, Philippe, additional, Parsaei, Shadi, additional, Pascual, Manuel A., additional, Patel, Rupa, additional, Patrozou, Eleni, additional, Pawlotsky, Jean-Michel, additional, Peacock, Sharon J., additional, Pechère, Jean-Claude, additional, Pelegrin, Ivan, additional, Peters, Barry S., additional, Peters, Edgar J.G., additional, Petersen, Jeannine M., additional, Petersen, Lyle R., additional, Petraitis, Vidmantas, additional, Pham, Luu-Ly, additional, Picado, Albert, additional, Pilatz, Adrian, additional, Pilmis, Benoit, additional, Pinazo, María-Jesús, additional, Pletz, Mathias W., additional, Pogue, Jason M., additional, Polgreen, Evelyn L., additional, Polgreen, Philip M., additional, Posfay-Barbe, Klara M., additional, Powderly, William G., additional, Presti, Rachel, additional, Prod'hom, Guy, additional, Puolakkainen, Mirja, additional, Quinn, Thomas C., additional, Raoult, Didier, additional, Razonable, Raymund R., additional, Read, Robert C., additional, Redfield, Robert R., additional, Rentenaar, Rob J., additional, Reynolds, Steven J., additional, Ribi, Camillo, additional, Richardson, Malcolm D., additional, Ritter, Michele L., additional, Roch, Antoine, additional, Rockstroh, Jürgen Kurt, additional, Rojek, Amanda, additional, Romero, José R., additional, Rooijakkers, Suzan H.M., additional, Rosenbluth, Daniel, additional, Rosenzweig, Sergio D., additional, Rossolini, Gian Maria, additional, Rubinstein, Ethan, additional, Ryan, Greg, additional, Safren, Steven A., additional, Sahasrabuddhe, Vikrant V., additional, Saikku, Pekka A.I., additional, Sajadi, Mohammad M., additional, Salvaggio, Michelle R., additional, Santos, Carlos A.Q., additional, Satlin, Michael J., additional, Schaeffer, Anthony J., additional, Schimmer, Christoph, additional, Schooley, Robert T., additional, Schumacher, Richard F., additional, Sha, Beverly E., additional, Shapiro, Daniel S., additional, Sheehan, Gerard, additional, Shlaes, David M., additional, Shoham, Shmuel, additional, Simmons, Cameron P., additional, Simon, Dennis W., additional, Simon, Matthew S., additional, Simonsen, Kari A., additional, Slack, Mary P.E., additional, Smith, Tyrel T., additional, Sobel, Jack D., additional, Souli, Maria, additional, Sridhar, Shruti, additional, Steckelberg, James M., additional, Stevens, Dennis L., additional, Strah, Heather, additional, Sturm, A. Willem, additional, Sungkanuparph, Somnuek, additional, Tabrizi, Sarah J., additional, Tacconelli, Evelina, additional, Tan, Chen Sabrina, additional, Taplitz, Randy A., additional, Thomas, Guillemette, additional, Thomas, Lora D., additional, Thuny, Franck, additional, Thwaites, Guy, additional, Tissot, Frederic, additional, Tønjum, Tone, additional, Torriani, Francesca J., additional, Toso, Christian, additional, Tulkens, Paul M., additional, Tunkel, Allan R., additional, Turner, Claire E., additional, Ustianowski, Andrew P., additional, van Bambeke, Françoise, additional, van Crevel, Reinout, additional, van de Beek, Diederik, additional, van Delden, Christian, additional, van der Eerden, Menno M., additional, van der Meer, Jos W.M., additional, van der Poll, Tom, additional, van Ingen, Jakko, additional, van Putten, Jos, additional, Vaudaux, Bernard P., additional, Vermund, Sten H., additional, Viscidi, Raphael P., additional, Visvanathan, Kumar, additional, Visvesvara, Govinda S., additional, von Seidlein, Lorenz, additional, Wagenlehner, Florian M.E., additional, Wald, Anna, additional, Walsh, Thomas J., additional, Warhurst, David C., additional, Warnock, David W., additional, Warrell, David A., additional, Warrell, Mary J., additional, Warris, Adilia, additional, Watkins, Richard R., additional, Weatherall, David J., additional, Weber, Rainer, additional, Weidner, Wolfgang, additional, White, Jonathan R., additional, White, Peter J., additional, Whitehorn, James, additional, Whitley, Richard J., additional, Whitty, Christopher J.M., additional, Wiersinga, Willem Joost, additional, Wilcox, Mark H., additional, Williams, Thomas N., additional, Wilson, Cara C., additional, Wilson, Mary Elizabeth, additional, Wisplinghoff, Hilmar, additional, Wood, Robin, additional, Wunderink, Richard G., additional, Wyles, David, additional, Yang, Zhi-Tao, additional, Yoder, Jonathan S., additional, Zaidi, Najam A., additional, Zimmer, Andrea J., additional, Zuckerman, Jane N., additional, and Zumla, Alimuddin, additional
- Published
- 2017
- Full Text
- View/download PDF
44. Correction to: Neisseria lactamica Y92–1009 complete genome sequence
- Author
-
Pandey, Anish K., Cleary, David W., Laver, Jay R., Maiden, Martin C. J., Didelot, Xavier, Gorringe, Andrew, and Read, Robert C.
- Published
- 2018
- Full Text
- View/download PDF
45. Controlled human infection with Neisseria lactamica in late pregnancy to measure horizontal transmission and microbiome changes in mother–neonate pairs: a single-arm interventional pilot study protocol
- Author
-
Theodosiou, Anastasia A, primary, Laver, Jay R, additional, Dale, Adam P, additional, Cleary, David W, additional, Jones, Christine E, additional, and Read, Robert C, additional
- Published
- 2022
- Full Text
- View/download PDF
46. Public attitudes to a human challenge study with SARS-CoV-2: a mixed-methods study
- Author
-
Barker, Caroline, primary, Collet, Katharine, additional, Gbesemete, Diane, additional, Piggin, Maria, additional, Watson, Daniella, additional, Pristerà, Philippa, additional, Lawerence, Wendy, additional, Smith, Emma, additional, Bahrami-Hessari, Michael, additional, Johnson, Halle, additional, Baker, Katherine, additional, Qavi, Ambar, additional, McGrath, Carmel, additional, Chiu, Christopher, additional, Read, Robert C., additional, and Ward, Helen, additional
- Published
- 2022
- Full Text
- View/download PDF
47. Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge
- Author
-
Killingley, Ben, primary, Mann, Alex, additional, Kalinova, Mariya, additional, Boyers, Alison, additional, Goonawardane, Niluka, additional, Zhou, Jie, additional, Lindsell, Kate, additional, Hare, Samanjit S., additional, Brown, Jonathan, additional, Frise, Rebecca, additional, Smith, Emma, additional, Hopkins, Claire, additional, Noulin, Nicolas, additional, Londt, Brandon, additional, Wilkinson, Tom, additional, Harden, Stephen, additional, McShane, Helen, additional, Baillet, Mark, additional, Gilbert, Anthony, additional, Jacobs, Michael, additional, Charman, Christine, additional, Mande, Priya, additional, Nguyen-Van-Tam, Jonathan S., additional, Semple, Malcolm G., additional, Read, Robert C., additional, Ferguson, Neil M., additional, Openshaw, Peter J., additional, Rapeport, Garth, additional, Barclay, Wendy S., additional, Catchpole, Andrew P., additional, and Chiu, Christopher, additional
- Published
- 2022
- Full Text
- View/download PDF
48. Immunogenicity and Reactogenicity of BNT162b2 and mRNA1273 COVID-19 Vaccines Given as Fourth Dose Boosters in the COV-BOOST Randomised Trial Following Two Doses of ChAdOx1 nCov-19 or BNT162b2 and a Third Dose of BNT162b2
- Author
-
Munro, Alasdair P.S, primary, Feng, Shuo, additional, Janani, Leila, additional, Cornelius, Victoria, additional, Aley, Parvinder K., additional, Babbage, Gavin, additional, Baxter, David, additional, Bula, Marcin, additional, Cathie, Katrina, additional, Chatterjee, Krishna, additional, Dodd, Kate, additional, Enever, Yvanne, additional, Qureshi, Ehsaan, additional, Goodman, Anna L., additional, Green, Christopher A., additional, Harndahl, Linda, additional, Haughney, John, additional, Hicks, Alexander, additional, van der Klaauw, Agatha A., additional, Kanji, Nasir, additional, Libri, Vincenzo, additional, Llewelyn, Martin J., additional, McGregor, Alastair C., additional, Minassian, Angela M., additional, Moore, Patrick, additional, Mughal, Mehmood, additional, Farooq Mujadidi, Yama, additional, Holliday, Kyra, additional, Osanlou, Orod, additional, Osanlou, Rostam, additional, Owens, Daniel R., additional, Pacurar, Mihaela, additional, Palfreeman, Adrian, additional, Pan, Daniel, additional, Rampling, Tommy, additional, Regan, Karen, additional, Saich, Stephen, additional, Bawa, Tanveer, additional, Saralaya, Dinesh, additional, Sharma, Sunil, additional, Sheridan, Ray, additional, Maalah, Mina, additional, Thomson, Emma C., additional, Todd, Shirley, additional, Twelves, Chris, additional, Read, Robert C., additional, Charlton, Sue, additional, Hallis, Bassam, additional, Ramsay, Mary E., additional, Andrews, Nick, additional, Lambe, Teresa, additional, Nguyen-Van-Tam, Jonathan S., additional, Snape, Matthew D., additional, Liu, Xinxue, additional, Faust, Saul N., additional, and Group, COV-BOOST Study, additional
- Published
- 2022
- Full Text
- View/download PDF
49. Bacterial Genomic Detection Within Cerebrospinal Fluid of Patients With Meningococcal Disease Is Influenced by Microbial and Host Characteristics
- Author
-
Darton, Tom C., Guiver, Malcolm, Naylor, Simone, Kaczmarski, Edward B., Borrow, Raymond, and Read, Robert C.
- Published
- 2011
- Full Text
- View/download PDF
50. Kinetics of Immune Responses to Nasal Challenge With Meningococcal Polysaccharide 1 Year After Serogroup-C Glycoconjugate Vaccination
- Author
-
Wing, James B., Smart, Lynne, Borrow, Ray, Findlow, Jamie, Findlow, Helen, Heath, Andrew W., and Read, Robert C.
- Published
- 2011
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.