209 results on '"Readhead, Ben"'
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2. Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimers pathology.
3. Systems modeling of metabolic dysregulation in neurodegenerative diseases
4. Abstract 13560: System Gene Regulatory Network-Based Drug Repurposing Combined With Preclinical Molecular Imaging Identifies Anti-Atherosclerotic Properties of Auranofin
5. Polygenic overlap between schizophrenia risk and antipsychotic response: a genomic medicine approach
6. Viral activation and ecological restructuring characterize a microbiome axis of spaceflight-associated immune activation
7. miR155 regulation of behavior, neuropathology, and cortical transcriptomics in Alzheimer's disease
8. Do infections have a role in the pathogenesis of Alzheimer disease?
9. Critical period plasticity-related transcriptional aberrations in schizophrenia and bipolar disorder
10. Automated detection of off-label drug use.
11. ReducedPIN1gene expression in neocortical and limbic brain regions in female Alzheimer's patients correlates with cognitive and neuropathological phenotypes
12. Rapamycin Modulates Glucocorticoid Receptor Function, Blocks Atrophogene REDD1, and Protects Skin from Steroid Atrophy
13. Integrative approach to sporadic Alzheimer’s disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden
14. Supplementary Tables 1-3 from A Novel Approach to Safer Glucocorticoid Receptor–Targeted Anti-lymphoma Therapy via REDD1 (Regulated in Development and DNA Damage 1) Inhibition
15. Supplementary Figures 1-9 from A Novel Approach to Safer Glucocorticoid Receptor–Targeted Anti-lymphoma Therapy via REDD1 (Regulated in Development and DNA Damage 1) Inhibition
16. Enabling Precision Cardiology Through Multiscale Biology and Systems Medicine
17. Correction to: Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits
18. Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits
19. Genome-wide analysis indicates association between heterozygote advantage and healthy aging in humans
20. Necroptosis activation in Alzheimer's disease
21. Pharmacological risk factors associated with hospital readmission rates in a psychiatric cohort identified using prescriptome data mining
22. Correction: Integrative approach to sporadic Alzheimer’s disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden
23. REDD1 functions at the crossroads between the therapeutic and adverse effects of topical glucocorticoids
24. Integrative Approach to Sporadic Alzheimer’s Disease: Deficiency of driver Tyrobp/Dap12 in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden
25. Repurposing the atypical antidepressant trazodone for atherosclerotic cardiovascular disease
26. A Novel Approach to Safer Glucocorticoid Receptor–Targeted Anti-lymphoma Therapy via REDD1 (Regulated in Development and DNA Damage 1) Inhibition
27. Systematic Analysis of Environmental Chemicals That Dysregulate Critical Period Plasticity-Related Gene Expression Reveals Common Pathways That Mimic Immune Response to Pathogen
28. Sexual dimorphism in atrophic effects of topical glucocorticoids is driven by differential regulation of atrophogene REDD1 in male and female skin
29. Clarifying the Potential Role of Microbes in Alzheimer’s Disease
30. Further evidence of increased human Herpesvirus in Alzheimer’s disease
31. Additional file 1: of Genome-wide analysis indicates association between heterozygote advantage and healthy aging in humans
32. Additional file 4: of Genome-wide analysis indicates association between heterozygote advantage and healthy aging in humans
33. Additional file 3: of Genome-wide analysis indicates association between heterozygote advantage and healthy aging in humans
34. Additional file 1: of Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits
35. Additional file 2: of Genome-wide analysis indicates association between heterozygote advantage and healthy aging in humans
36. Absence of TYROBP in a mouse model of Alzheimer’s amyloidosis recapitulates human Alzheimer’s-predicted complement network and prevents functional deficits
37. Integrative transcriptome imputation reveals tissue-specific and shared biological mechanisms mediating susceptibility to complex traits
38. Systems Pharmacology Identifies an Arterial Wall Regulatory Gene Network Mediating Coronary Artery Disease Side Effects of Antiretroviral Therapy
39. PI3K inhibitors protect against glucocorticoid-induced skin atrophy
40. Correction: Integrative approach to sporadic Alzheimer’s disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden
41. Deletion of the glucocorticoid receptor chaperone FKBP51 prevents glucocorticoid-induced skin atrophy
42. Integrative approach to sporadic Alzheimer’s disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden
43. Abstract B023: Identification and biochemical validation of piperlongumine as a potent therapeutic against neuroendocrine prostate cancer
44. Multiscale Analysis of Independent Alzheimer’s Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus
45. Landscape of Conditional eQTL in Dorsolateral Prefrontal Cortex and Co-localization with Schizophrenia GWAS
46. Rapid Therapeutic Recommendations in the Context of a Global Public Health Crisis using Translational Bioinformatics Approaches: A proof-of-concept study using Nipah Virus Infection
47. Prioritizing Small Molecule as Candidates for Drug Repositioning using Machine Learning
48. Exploring the Interaction Between eIF2α Dysregulation, Acute Endoplasmic Reticulum Stress and DYT1 Dystonia in the Mammalian Brain
49. Mutations in THAP1/DYT6 reveal that diverse dystonia genes disrupt similar neuronal pathways and functions
50. Cross-Tissue Regulatory Gene Networks in Coronary Artery Disease
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