1. Peripheral nerve blocks with liposomal bupivacaine are associated with increased opioid use compared to thoracic epidural in patients with an epigastric incision
- Author
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Elena P Padilla, Daniel E. Abbott, Taylor Aiken, Sharon M. Weber, Deborah Lemaster, Sean Ronnekleiv-Kelly, Rebecca M. Minter, and Steven Ethier
- Subjects
Ileus ,business.industry ,Urinary retention ,Cancer ,General Medicine ,Liposomal Bupivacaine ,medicine.disease ,Article ,Oncology ,Thoracic epidural ,Transversus Abdominis Plane Block ,Surgical oncology ,Anesthesia ,Morphine ,Medicine ,Surgery ,medicine.symptom ,business ,medicine.drug - Abstract
BACKGROUND Thoracic epidurals are commonly recommended in enhanced recovery protocols, though they may cause hypotension and urinary retention. Peripheral nerve blocks using liposomal bupivacaine are a potential alternative, though they have not been extensively studied in major cancer operations with an epigastric incision. METHODS We conducted a retrospective review of prospectively collected data following the transition from thoracic epidural to liposomal peripheral nerve blocks in patients undergoing major oncologic surgery. Patients receiving peripheral nerve blocks were compared to those receiving thoracic epidural. Outcome variables included postoperative opioid use (milligram morphine equivalents [MME]), severe pain, and postoperative complications. RESULTS Forty-seven of 102 patients studied (46%) received peripheral nerve blocks. Opioid use was higher in the peripheral nerve block group during the 0-24 h (116 vs. 94 MME, p = 0.04) and 24-48 h postoperative period (94 vs. 23 MME, p
- Published
- 2021
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