Search

Your search keyword '"Reckman, Yolan J."' showing total 20 results
Start Over Author "Reckman, Yolan J."
20 results on '"Reckman, Yolan J."'

6. Titin Circular RNAs Create a Back-Splice Motif Essential for SRSF10 Splicing

Author

Tijsen, Anke J., primary, Cócera Ortega, Lucía, additional, Reckman, Yolan J., additional, Zhang, Xiaolei, additional, van der Made, Ingeborg, additional, Aufiero, Simona, additional, Li, Jiuru, additional, Kamps, Selina C., additional, van den Bout, Anouk, additional, Devalla, Harsha D., additional, van Spaendonck-Zwarts, Karin Y., additional, Engelhardt, Stefan, additional, Gepstein, Lior, additional, Ware, James S., additional, and Pinto, Yigal M., additional

Published
2021
Full Text
View/download PDF

7. Quantification of Myocardial Creatine and Triglyceride Content in the Human Heart: Precision and Accuracy of in vivo Proton Magnetic Resonance Spectroscopy

Author

Bakermans, Adrianus J., primary, Boekholdt, S. Matthijs, additional, Vries, Dylan K., additional, Reckman, Yolan J., additional, Farag, Emile S., additional, Heer, Paul, additional, Uthman, Laween, additional, Denis, Simone W., additional, Zuurbier, Coert J., additional, Houtkooper, Riekelt H., additional, Koolbergen, David R., additional, Kluin, Jolanda, additional, Planken, R. Nils, additional, Lamb, Hildo J., additional, Webb, Andrew G., additional, Strijkers, Gustav J., additional, Beard, Daniel A., additional, Jeneson, Jeroen A.L., additional, and Nederveen, Aart J., additional

Published
2021
Full Text
View/download PDF

8. Variants in the 3′ untranslated region of the KCNQ1-encoded Kv7.1 potassium channel modify disease severity in patients with type 1 long QT syndrome in an allele-specific manner

Author

Amin, Ahmad S., Giudicessi, John R., Tijsen, Anke J., Spanjaart, Anne M., Reckman, Yolan J., Klemens, Christine A., Tanck, Michael W., Kapplinger, Jamie D., Hofman, Nynke, Sinner, Moritz F., Müller, Martina, Wijnen, Wino J., Tan, Hanno L., Bezzina, Connie R., Creemers, Esther E., Wilde, Arthur A. M., Ackerman, Michael J., and Pinto, Yigal M.

Published
2012
Full Text
View/download PDF

11. Therapeutic Delivery of miR-148a Suppresses Ventricular Dilation in Heart Failure

Author

Raso, Andrea, primary, Dirkx, Ellen, additional, Philippen, Leonne E., additional, Fernandez-Celis, Amaya, additional, De Majo, Federica, additional, Sampaio-Pinto, Vasco, additional, Sansonetti, Marida, additional, Juni, Rio, additional, el Azzouzi, Hamid, additional, Calore, Martina, additional, Bitsch, Nicole, additional, Olieslagers, Servé, additional, Oerlemans, Martinus I.F.J., additional, Huibers, Manon M., additional, de Weger, Roel A., additional, Reckman, Yolan J., additional, Pinto, Yigal M., additional, Zentilin, Lorena, additional, Zacchigna, Serena, additional, Giacca, Mauro, additional, da Costa Martins, Paula A., additional, López-Andrés, Natalia, additional, and De Windt, Leon J., additional

Published
2019
Full Text
View/download PDF

12. Yield and pitfalls of ajmaline testing in the evaluation of unexplained cardiac arrest and sudden unexplained death: Single centre experience of 482 families

Author

Tadros, Rafik, Nannenberg, Eline A., Lieve, Krystien V., Skoric-Milosavljevic, Doris, Lahrouchi, Najim, Lekanne Dit Deprez, Ronald H., Vendrik, Jeroen, Reckman, Yolan J., Postema, Pieter G., Amin, Ahmad S., Bezzina, Connie R., Wilde, Arthur A. M., Tan, Hanno L., Human Genetics, ACS - Amsterdam Cardiovascular Sciences, Graduate School, Cardiology, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Other Research, ACS - Heart failure & arrhythmias, ACS - Pulmonary hypertension & thrombosis, ACS - Microcirculation, and ACS - Atherosclerosis & ischemic syndromes

Published
2017

15. RBM20 Regulates Circular RNA Production From the Titin Gene

Author

Khan, Mohsin A.F., primary, Reckman, Yolan J., additional, Aufiero, Simona, additional, van den Hoogenhof, Maarten M.G., additional, van der Made, Ingeborg, additional, Beqqali, Abdelaziz, additional, Koolbergen, Dave R., additional, Rasmussen, Torsten B., additional, van der Velden, Jolanda, additional, Creemers, Esther E., additional, and Pinto, Yigal M., additional

Published
2016
Full Text
View/download PDF

17. Variants in the 3′ untranslated region of the KCNQ1-encoded Kv7.1 potassium channel modify disease severity in patients with type 1 long QT syndrome in an allele-specific manner

Author

Amin, Ahmad S., primary, Giudicessi, John R., additional, Tijsen, Anke J., additional, Spanjaart, Anne M., additional, Reckman, Yolan J., additional, Klemens, Christine A., additional, Tanck, Michael W., additional, Kapplinger, Jamie D., additional, Hofman, Nynke, additional, Sinner, Moritz F., additional, Müller, Martina, additional, Wijnen, Wino J., additional, Tan, Hanno L., additional, Bezzina, Connie R., additional, Creemers, Esther E., additional, Wilde, Arthur A. M., additional, Ackerman, Michael J., additional, and Pinto, Yigal M., additional

Published
2011
Full Text
View/download PDF

18. Abstract 28.

Author

Tijsen, Anke J, van der Made, Ingeborg, van Deel, Elza D, Hiller, Monika, Reckman, Yolan J, Duncker, Dirk J, Pinto, Yigal M, and Creemers, Esther E

Published
2012

19. Therapeutic Delivery of miR-148a Suppresses Ventricular Dilation in Heart Failure

Author

Mauro Giacca, Hamid el Azzouzi, Lorena Zentilin, Martinus I. F. J. Oerlemans, Natalia López-Andrés, Yigal M. Pinto, Paula A. da Costa Martins, Serena Zacchigna, Manon M. H. Huibers, Marida Sansonetti, Martina Calore, Andrea Raso, Roel A. de Weger, Leon J. De Windt, Amaya Fernández-Celis, Leonne E Philippen, Rio P. Juni, Nicole Bitsch, Federica De Majo, Servé Olieslagers, Ellen Dirkx, Vasco Sampaio-Pinto, Yolan J. Reckman, Raso, Andrea, Dirkx, Ellen, Philippen, Leonne E., Fernandez-Celis, Amaya, De Majo, Federica, Sampaio-Pinto, Vasco, Sansonetti, Marida, Juni, Rio, el Azzouzi, Hamid, Calore, Martina, Bitsch, Nicole, Olieslagers, Servé, Oerlemans, Martinus I. F. J., Huibers, Manon M., de Weger, Roel A., Reckman, Yolan J., Pinto, Yigal M., Zentilin, Lorena, Zacchigna, Serena, Giacca, Mauro, da Costa Martins, Paula A., López-Andrés, Natalia, De Windt, Leon J., Cardiologie, RS: CARIM - R2 - Cardiac function and failure, RS: CARIM - R2.07 - Gene regulation, Promovendi CD, RS: FSE DMG, Ondersteunend personeel CD, RS: Carim - Heart, RS: Carim - H05 Gene regulation, RS: CARIM School for Cardiovascular Diseases, Cardiology, Graduate School, ACS - Heart failure & arrhythmias, Physiology, and ACS - Microcirculation

Subjects
adeno-associated vector, cardiac, heart failure, hypertrophy, microRNA, miR-148a, signaling, Molecular Medicine, Molecular Biology, Genetics, Pharmacology, Drug Discovery3003 Pharmaceutical Science, Volume overload, Muscle hypertrophy, Mice, 0302 clinical medicine, Drug Discovery, Medicine, CARDIAC-HYPERTROPHY, IN-VIVO, 0303 health sciences, Ejection fraction, Ventricular Remodeling, GP130, Dilated cardiomyopathy, 3. Good health, BRAIN NATRIURETIC PEPTIDE, 030220 oncology & carcinogenesis, SURVIVAL, Cardiology, Original Article, Cardiomyopathies, Signal Transduction, STAT3 Transcription Factor, EXPRESSION, INTERLEUKIN-6 FAMILY, medicine.medical_specialty, Concentric hypertrophy, Cardiomegaly, MYOCYTES, 03 medical and health sciences, Genetic, Internal medicine, Journal Article, Animals, Humans, PLASMA CARDIOTROPHIN-1, Ventricular remodeling, Cell Proliferation, 030304 developmental biology, Pressure overload, business.industry, Myocardium, medicine.disease, Dilatation, GENE, MicroRNAs, Heart failure, Commentary, Heart Transplantation, business
Abstract

Heart failure is preceded by ventricular remodeling, changes in left ventricular mass, and myocardial volume after alterations in loading conditions. Concentric hypertrophy arises after pressure overload, involves wall thickening, and forms a substrate for diastolic dysfunction. Eccentric hypertrophy develops in volume overload conditions and leads wall thinning, chamber dilation, and reduced ejection fraction. The molecular events underlying these distinct forms of cardiac remodeling are poorly understood. Here, we demonstrate that miR-148a expression changes dynamically in distinct subtypes of heart failure: while it is elevated in concentric hypertrophy, it decreased in dilated cardiomyopathy. In line, antagomir-mediated silencing of miR-148a caused wall thinning, chamber dilation, increased left ventricle volume, and reduced ejection fraction. Additionally, adeno-associated viral delivery of miR-148a protected the mouse heart from pressure-overload-induced systolic dysfunction by preventing the transition of concentric hypertrophic remodeling toward dilation. Mechanistically, miR-148a targets the cytokine co-receptor glycoprotein 130 (gp130) and connects cardiomyocyte responsiveness to extracellular cytokines by modulating the Stat3 signaling. These findings show the ability of miR-148a to prevent the transition of pressure-overload induced concentric hypertrophic remodeling toward eccentric hypertrophy and dilated cardiomyopathy and provide evidence for the existence of separate molecular programs inducing distinct forms of myocardial remodeling., Raso et al. show that miR-148a is elevated in concentric hypertrophy and decreased in dilated cardiomyopathy. Adeno-associated viral delivery of miR-148a protects the mouse heart from cardiac dilation. Mechanistically, miR-148a regulates the sensitivity of the heart to extracellular cytokines.

Published
2019

Catalog

Books, media, physical & digital resources
See catalog results