Search

Your search keyword '"Regad SB"' showing total 2 results
Start Over Author "Regad SB"
2 results on '"Regad SB"'

1. Comparison of the predictive values of diagnostic tests subject to a case-control sampling with application to the diagnosis of Human African Trypanosomiasis

Author

Sidaty-Regad Sb and Roldán-Nofuentes Ja

Subjects
education.field_of_study, McNemar's test, Positive predicative value, Population, Statistics, Prevalence, Estimator, Sampling (statistics), Sample (statistics), education, Statistical hypothesis testing, Mathematics
Abstract

Case-control sampling to compare the accuracy of two binary diagnostic tests is frequent in clinical practice. This type of sampling consists of applying the two diagnostic tests to all of the individuals in a sample of those who have the disease and in another sample of those who do not have the disease. In this sampling, the sensitivities are compared from the case sample applying the McNemar’s test, and the specificities from the control sample. Other parameters of binary tests are the positive and negative predictive values. The predictive values of a diagnostic test represent the clinical accuracy of a binary diagnostic test when it is applied to the individuals in a population with a determined disease prevalence. This article studies the comparison of the predictive values of two diagnostic tests subject to a case-control sampling. A global hypothesis test, based on the chi-square distribution, is proposed to compare the predictive values simultaneously. The comparison of the predictive values is also studied individually. The hypothesis tests studied require knowledge of the disease prevalence. Simulation experiments were carried out to study the type I errors and the powers of the hypothesis tests proposed, as well as to study the effect of a misspecification of the prevalence on the asymptotic behavior of the hypothesis tests and on the estimators of the predictive values. The results obtained were applied to a real example on the diagnosis of the Human African Trypanosomiasis. The model proposed was extended to the situation in which there are more than two diagnostic tests.

Published
2019
Full Text
View/download PDF

2. Prevalence and factors associated with neonatal mortality among neonates hospitalized at the National Hospital Nouakchott, Mauritania.

Author

Weddih A, Ahmed MLCB, Sidatt M, Abdelghader N, Abdelghader F, Ahmed A, Regad SB, Makhalla K, Heukelbach J, and Barkat A

Subjects
Adult, Cross-Sectional Studies, Female, Humans, Infant, Infant, Low Birth Weight, Infant, Newborn, Male, Mauritania epidemiology, Pregnancy, Prevalence, Risk Factors, Young Adult, Hospitalization statistics & numerical data, Infant Mortality, Prenatal Care statistics & numerical data
Abstract

Introduction: Neonatal mortality remains a significant public health burden worldwide, with about 4 million deaths per year. To provide evidence for the implementation of prevention measures aimed at the reduction of neonatal mortality, we performed a study on factors associated with neonatal mortality at the Referral Hospital in Nouakchott, Mauritania., Methods: We conducted a cross-sectional study between January 2013 and December 2013 and included neonatal patients hospitalized at the National Referral Hospital (NRH). Data were collected by reviewing the medical charts and through questionnaires administered to the parents., Results: Two hundred and thirty-two (34.7%) of the 669 neonates included in the study died; 159 (71.3%) of deaths occurred during the first six days of life. Most neonates that died were born outside the hospital and admitted to NRH after birth (71.7%; 142/198). About 1/3 were transferred from other parts of the country outside of Nouakchott. Thirty (13.4%) of deaths were neonates born from teenage mothers. In bivariate analysis teenage mothers (RR=1.54; 95% CI: 1.15-2.05; p = 0.004), illiteracy of father (1.61; 1.13-23.0; p = 0.007), birth outside NRH (1.65; 1.28-2.13; p < 0.0001), low gestational age (3.28; 2.40-5.50; p < 0.0001), and low body temperature at admission (1.42; 1.11-1.83; p < 0.004) were significantly associated with neonatal death. In logistic regression analysis, low birth weight (adjusted odds ratio = 3.91; 95% confidence interval 1.69-9.05; p = 0.001), hypothermia (2.40; 1.12-5.14; p = 0.025), and birth outside the NRH (2.13; 1.02-4.45; p = 0.044) were independently associated with neonatal deaths., Conclusion: Neonatal mortality remains a significant burden in Mauritania. We identified different socioeconomic and clinical risk factors indicating the need for more intensified prenatal care and improved transport of high risk neonates, especially in the regions outside the capital., Competing Interests: The authors declare no competing interests., (© Abdellahi Weddih et al.)

Published
2019
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results