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Your search keyword '"Ren, Xiao-min"' showing total 301 results
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301 results on '"Ren, Xiao-min"'

1. Agrochemicals and obesity

Author

Ren, Xiao-Min, Kuo, Yun, and Blumberg, Bruce

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Obesity, Nutrition, Prevention, 2.3 Psychological, social and economic factors, 2.1 Biological and endogenous factors, Aetiology, 2.2 Factors relating to the physical environment, Stroke, Cancer, Cardiovascular, Oral and gastrointestinal, Agrochemicals, Animals, Endocrine Disruptors, Environmental Exposure, Environmental Pollutants, Genetic Predisposition to Disease, Humans, Obesogen, EDC, Endocrine disrupting chemical, Agrochemical, Pesticide, Fungicide, Transgenerational, Epigenetic, Microbiome, Biological Sciences, Agricultural and Veterinary Sciences, Medical and Health Sciences, Endocrinology & Metabolism, Biochemistry and cell biology, Genetics, Clinical sciences
Abstract

Obesity has become a very large concern worldwide, reaching pandemic proportions over the past several decades. Lifestyle factors, such as excess caloric intake and decreased physical activity, together with genetic predispositions, are well-known factors related to obesity. There is accumulating evidence suggesting that exposure to some environmental chemicals during critical windows of development may contribute to the rapid increase in the incidence of obesity. Agrochemicals are a class of chemicals extensively used in agriculture, which have been widely detected in human. There is now considerable evidence linking human exposure to agrochemicals with obesity. This review summarizes human epidemiological evidence and experimental animal studies supporting the association between agrochemical exposure and obesity and outlines possible mechanistic underpinnings for this link.

Published
2020

10. Single-Mode Vertical Cavity Surface Emitting Laser via High-Order Transverse Mode Expansion

Author

Liu, Kai, Zhong, Yun-Feng, Dong, Xiao-Wen, Huang, Yong-Qing, Duan, Xiao-Feng, Ren, Xiao-Min, Cai, Shi-Wei, and Wang, Qi

Abstract

In this article, we propose a method of realizing single mode VCSEL by expanding its higher order transverse mode more out of its gain region, while maintaining its fundamental mode inside. This will result in less optical gain for the VCSEL's higher order mode than that for its fundamental mode, and then result in the single mode output of the VCSEL. A Top Cavity and a Bottom Cavity are introduced into VCSEL's top and bottom DBR respectively to achieve this purpose. The mode expansion phenomenon is verified by simulation, and the VCSEL is fabricated. Finally, a single-mode VCSEL with a side-mode suppression ratio greater than 40 dB, a threshold current of 0.5 mA, and a maximum output power of 0.27 mW is obtained.

Published
2023
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15. Benzotriazole Ultraviolet Stabilizers Promote Breast Cancer Cell Proliferation via Activating Estrogen-Related Receptors α and γ at Human-Relevant Levels

Author

He, Sen, primary, Xiao, Han, additional, Luo, Shuang, additional, Li, Xin, additional, Zhang, Jia-Da, additional, Ren, Xiao-Min, additional, Yang, Yuan, additional, Xie, Xian-De, additional, Zhou, Yao-Yu, additional, Yin, Yu-Long, additional, Luo, Lin, additional, and Cao, Lin-Ying, additional

Published
2022
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20. Influence of the incident optical field distribution on a high-speed PIN photodetector and horizontal optimization

Author

Ren Xiao-min, Liu Kai, Huang Yongqing, Niu Huijuan, Yang Yisu, Duan Xiaofeng, Zhi Huayun, Yuan Weifang, and Xiao Chaozheng

Subjects
Physics, business.industry, Photodetector, Optical field, 01 natural sciences, Atomic and Molecular Physics, and Optics, Power (physics), 010309 optics, Light intensity, Optics, Distribution (mathematics), Electric field, 0103 physical sciences, Bandwidth (computing), Electrical and Electronic Engineering, Coaxial, business, Engineering (miscellaneous)
Abstract

We demonstrate a new, to the best of our knowledge, dimensional “horizontal optimization” scheme, which can improve the high-speed characteristics of a PIN photodetector by designing the incident optical field distribution. First, coaxially incident faculae with the same peak and same power are studied and simulated, revealing that the bandwidth of the photodetector illuminated by uniform light is higher than that of the device illuminated by nonuniform light. Next, an annular optical field is designed incident to the photodetector, and the bandwidth is further improved. For a PIN photodetector, by carefully optimizing the incident optical field distribution, the photodetector bandwidth under an annular optical field can be increased significantly compared with that under conventional coaxial illumination.

Published
2021

26. High-speed and large-responsivity synchronous-traveling carrier photodetector

Author

Huang Yongqing, Ren Xiao-min, Yuan Weifang, Li Gongqing, Liu Kai, Li Ke, Li Yu, and Duan Xiaofeng

Subjects
Frequency response, Materials science, business.industry, Photodetector, Diffusion capacitance, Atomic and Molecular Physics, and Optics, Responsivity, Optics, Electric field, Band diagram, Electrical and Electronic Engineering, Absorption (electromagnetic radiation), business, Engineering (miscellaneous), Refractive index
Abstract

A synchronous-traveling carrier photodetector (STC-PD) with a thick absorption region and large diameter is presented and investigated for 100 Gbps PAM4 applications. In the STC structure, a suitable electric field is introduced to synchronize the traveling of electrons and holes, which achieves high bandwidth while maintaining large responsivity. The characteristics of STC-PD, including electric field distribution, energy band diagram, responsivity, junction capacitance, and frequency response, have been studied carefully.

Published
2021

38. First-principles Study on Electronic Structure and Optical Properties of Single Point Defect Graphene Oxide

Author

Lin Qi-Min, Cui Jian-Gong, Yan Xin, Zhang Xia, Chen Xiaoyu, LU Qichao, Ren Xiao-min, Yuan Xueguang, Huang Xue, and Luo Yanbin

Subjects
Materials science, Graphene, business.industry, Optical property, Oxide, Electronic structure, law.invention, Inorganic Chemistry, Absorbance, chemistry.chemical_compound, chemistry, law, Optoelectronics, General Materials Science, Single point, business
Published
2020

48. Hydroxylated Polybrominated Biphenyl Ethers Exert Estrogenic Effects via Non-Genomic G Protein-Coupled Estrogen Receptor Mediated Pathways

Author

Cao, Lin-Ying, Ren, Xiao-Min, Yang, Yu, Wan, Bin, Guo, Liang-Hong, Chen, De, and Fan, Yong

Subjects
Hewlett-Packard Co., Adenosine monophosphate, Estradiol, Cyclic adenosine monophosphate, Transcription (Genetics), Polybrominated biphenyls -- Risk factors, Estrogens -- Analysis, Phenols (Class of compounds), Flame retardants -- Risk factors, Computer industry, Microcomputer industry, Computer industry, Environmental issues, Health
Abstract

BACKGROUND: Numerous studies have indicated the estrogenic effects of polybrominated diphenyl ethers (PBDEs) and hydroxylated PBDEs (OH-PBDEs). However, the previous mechanistic studies focused on their estrogenic effects through genomic transcriptional activation of estrogen receptors. OBJECTIVE: The present study aimed to investigate the estrogenic effects of PBDEs and OH-PBDEs via nongenomic G protein-coupled estrogen receptor (GPER) pathways. METHODS: The binding affinities of 12 PBDEs and 18 OH-PBDEs with GPER were determined by a fluorescence competitive binding assay in a human breast cancer cell line (SKBR3). Molecular docking was performed to simulate the interactions. Their activities on GPER pathways were investigated by detecting calcium mobilization and cyclic adenosine monophosphate (cAMP) accumulation in SKBR3 cells. The effects on SKBR3 cell migration were investigated using Boyden chamber and wound-healing assays. RESULTS: Our results showed that 11 of the OH-PBDEs but none of the PBDEs bound to GPER directly. Relative binding affinities ranged from 1.3% to 20.0% compared to 17[beta]-estradiol. Docking results suggested that the hydroxyl group played an essential role in the binding of OH-PBDEs to GPER by forming hydrogen bond interactions. Most of the OH-PBDEs activated subsequent GPER signaling pathways. Among them, 4'-OH-BDE-049, 5'-OH-BDE-099, and 3'-OH-BDE-154 displayed the highest activity with lowest effective concentrations (LOECs) of 10-100 nM. These three OH-PBDEs also promoted SKBR3 cell migration via GPER pathways with LOECs of 0.1- 1 [micro]M. CONCLUSION: OH-PBDEs could bind to GPER, activate the subsequent signaling pathways, and promote SKBR3 cell migration via GPER pathways. OH-PBDEs might exert estrogenic effects by a novel nongenomic mechanism involving the activation of GPER at nanomolar concentrations. https:// doi.org/10.1289/EHP2387, Introduction Polybrominated diphenyl ethers (PBDEs) have been and are currently used as flame retardant additives in a variety of industrial and consumer products such as plastic materials and textile fabrics [...]

Published
2018
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49. Electronic Structure Modulation of GaAs Nanowires by Surface Modification

Author

Zhang Xia, Telecommunications, Beijing , P. R. China, Cui Jian-Gong, Huang Yongqing, Ren Xiao-min, LI Jun-Shuai, and Yan Xin

Subjects
Materials science, Modulation, business.industry, Nanowire, Surface modification, Optoelectronics, Electronic structure, Physical and Theoretical Chemistry, business
Published
2014

50. First-principles study on structural stability of graphene oxide and catalytic activity of nitric acid

Author

Cui Jian-Gong, Huang Xue, Luo Yanbin, Ren Xiao-min, Yan Xin, Lu Qi-Chao, Lin Qi-Min, and Zhang Xia

Subjects
Materials science, Graphene, Oxide, General Physics and Astronomy, Electronic structure, 01 natural sciences, Endothermic process, Catalysis, law.invention, chemistry.chemical_compound, chemistry, law, Nitric acid, 0103 physical sciences, Physical chemistry, Work function, Direct and indirect band gaps, 010306 general physics
Abstract

The stability and electronic structure properties of graphene fumigated by nitric acid are systematically studied by the first-principles method based on ultrasoft pseudopotentials. The model of graphene oxide fumigated by nitric acid is built based on the 2 × 2 supercell model with orthogonal graphene unit cells, which contains 15 carbon and 2 oxygen atoms. The results show that the fumigated graphene containing a carbon atom bonded to an oxygen atom is a stable structure with lower energy, which is consistent with the experimental result. In addition, the mechanical stability analysis shows \begin{document}${ {C_{66}} > 0,\;{C_{11}} > 0,\;{C_{11}}{C_{22}} > C_{12}^2} $\end{document}, which satisfies the mechanical stability condition. By analyzing the reactant and product, it can be concluded that the nitric acid acts as catalyst. Moreover, the process of graphene oxidation catalyzed by nitric acid is endothermic and the reaction needs heating. By analyzing the electronic properties of the structure, the graphene oxide is determined to be an intrinsic semiconductor with a direct band gap of 1.12 eV and work function of 5.28 eV. These results provide theoretical basis for preparing the graphene oxide and its applications in the field of optoelectronic devices.

Published
2019

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