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Background: Stunting is a major health problem in developing countries due to chronic malnutrition that impacts physical growth, cognitive ability, and long-term productivity. The focus of stunting prevention is generally aimed at pregnant women and toddlers, while adolescents, especially adolescent girls, are often neglected. In fact, they will be the future mothers who determine the quality of the next generation. Malnutrition and anemia in adolescents increase the risk of giving birth to stunted children. Innovative nutritional intervention programs, such as nutrition education and iron supplements, are needed to break the cycle of stunting, involving adolescents as important targets in prevention. Karuni is a program specifically designed for teenagers aged 12-15 years with the main focus being on empowering teenagers through nutrition education, reproductive health and clean and healthy living behavior as well as involving parents to optimize the program., Methods: This study used a phenomenological approach to explore the understanding of adolescent girls aged 12-15 years about the stunting prevention program in Gunungkidul Regency, Indonesia. Data were collected through in-depth interviews and FGDs with adolescents, officials running the Adolescent Health Care (PKPR) program, and related agencies. Data validity was guaranteed by triangulation of sources and NVivo was used for analysis., Results: The identified five themes related to the adolescent intervention program for stunting prevention: program implementation, achievements, barriers, needs, and KARUNI model design. Program monitoring is important, but faces barriers such as the lack of prioritization and motivation. Cross-sectoral collaboration, innovation, and appropriate media are needed in the implementation of the KARUNI model to increase the effectiveness of the stunting prevention program for adolescents., Conclusions: The importance of the role of adolescents in efforts to reduce the prevalence of stunting, especially through collaboration between health centers ( Puskesmas ) and schools in implementing the PKPR program, providing iron tablets, and health screening., (© 2025 the author(s), published by De Gruyter, Berlin/Boston.)

Objective: We provide an overview of the safety of messenger RNA and inactivated coronavirus disease 2019 (COVID-19) vaccine and monitoring of pregnant women after COVID-19 vaccination. The vaccine safety outcome profile is beneficial for further recommendations of COVID-19 vaccination in pregnancy., Methods: This research was conducted as descriptive research. Sampling was performed using an online questionnaire to be filled out voluntarily and distributed to all pregnant women in Indonesia who received the COVID-19 vaccination. Data collection was performed and descriptive statistics were obtained., Results: Among 31 977 pregnant women, 24 212 (75.7%) received the first dose, 7619 (23.8%) received the second dose, and 146 (4.5%) received the third dose of the COVID-19 vaccine. Sinovac vaccine is the most administered vaccine to pregnant women (27 122 [84%]). Most pregnant women (78.7%) who were vaccinated had no adverse effects after immunization, while the most reported adverse effects were mild symptoms., Conclusion: The current study contributed evidence that COVID-19 vaccination during pregnancy has minimal adverse effects. These findings may help pregnant women and healthcare providers to make informed decisions regarding vaccination., (© 2023 The Authors. International Journal of Gynecology & Obstetrics published by John Wiley & Sons Ltd on behalf of International Federation of Gynecology and Obstetrics.)

Background: Some studies have reported that preeclampsia with coronavirus disease 2019 (COVID-19) significantly increases the risk of adverse perinatal outcome until near to three-fold over the normal pregnancy. Preeclampsia pathophysiology in theory, increases the perinatal mortality and morbidity starting from placental injury which is also believed to share the common pathway with COVID-19 infection. Major typical placental injuries for these matters could be apoptotic, necrotic, or pyroptotic., Objective: This study aimed to compare placental damage between those three conditions above in those three typical injuries., Study Design: This was an observational analytic study with cross-sectional setting. Seventy-two pregnant women admitted to hospital consecutively with diagnosis of preeclampsia with COVID-19, Preeclampsia only and COVID-19 only. Diagnosis for preeclampsia was following FIGO criteria with at least one of the severe features. COVID-19 eligible for this study was PCR test confirmative with moderate to severe clinical degree. Placenta were taken after the delivery, and parameters were quantified with immunohistochemistry test for caspase-3, caspase-1, and TNF-alpha representing apoptotic, pyroptotic, and necrotic pathway respectively., Results: Pregnancy with double complications, preeclampsia, and COVID-19, significantly has the highest placental damage on apoptotic, pyroptotic, and necrotic pathway shown from the caspase-3, caspase-1, and TNF-alpha expression in placenta (p <0.05). Moderate to severe degree of COVID-19 resulting higher placental damage compared to preeclampsia in all the three forms (p <0.05). Apoptotic process was the most prominent among other pathways., Conclusion: Preeclampsia with COVID-19 infection showed significant placental damage, with major changes related were apoptosis, inflammation, and necrosis. This data support poor perinatal outcome of pregnancy having preeclampsia and COVID-19 at the same time., (© 2023 Published by Elsevier Inc.)