17 results on '"Rettegno, Sara"'
Search Results
2. Average daily ischemic versus bleeding risk in patients with ACS undergoing PCI: Insights from the BleeMACS and RENAMI registries
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D’Ascenzo, Fabrizio, Biolè, Carloalberto, Raposeiras-Roubin, Sergio, Gaido, Federico, Abu-Assi, Emad, Kinnaird, Tim, Ariza-Solé, Albert, Liebetrau, Christoph, Manzano-Fernández, Sergio, Boccuzzi, Giacomo, Henriques, Jose Paulo Simao, Templin, Christian, Wilton, Stephen B., Omedè, Pierluigi, Velicki, Lazar, Xanthopoulou, Ioanna, Correia, Luis, Cerrato, Enrico, Rognoni, Andrea, Fabrizio, Ugo, Nuñez-Gil, Iván, Montabone, Andrea, Taha, Salma, Fujii, Toshiharu, Durante, Alessandro, Song, Xiantao, Gili, Sebastiano, Magnani, Giulia, Autelli, Michele, Bongiovanni, Federica, Grosso, Alberto, Kawaji, Tetsuma, Blanco, Pedro Flores, Garay, Alberto, Quadri, Giorgio, Alexopoulos, Dimitrios, Queija, Berenice Caneiro, Huczek, Zenon, Paz, Rafael Cobas, González-Juanatey, José Ramón, Fernández, María Cespón, Nie, Shao-Ping, Pousa, Isabel Muñoz, Kawashiri, Masa-aki, Rettegno, Sara, Gallo, Diego, Morbiducci, Umberto, Conrotto, Federico, Dominguez-Rodriguez, Alberto, Valdés, Mariano, Cequier, Angel, Iñiguez-Romo, Andrés, Biondi-Zoccai, Giuseppe, Stone, Gregg W., and De Ferrari, Gaetano Maria
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- 2020
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3. Incidence and Management of Restenosis After Treatment of Unprotected Left Main Disease With Second-Generation Drug-Eluting Stents (from Failure in Left Main Study With 2nd Generation Stents–Cardiogroup III Study)
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D'Ascenzo, Fabrizio, Chieffo, Alaide, Cerrato, Enrico, Ugo, Fabrizio, Pavani, Marco, Kawamoto, Hyroishi, di Summa, Roberto, Varbella, Ferdinando, Boccuzzi, Giacomo, Omedè, Pierluigi, Rettegno, Sara, Garbo, Roberto, Conrotto, Federico, Montefusco, Antonio, Biondi-Zoccai, Giuseppe, D'Amico, Maurizio, Moretti, Claudio, Escaned, Javier, Gaita, Fiorenzo, and Colombo, Antonio
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- 2017
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4. Is pericardial effusion a negative prognostic marker? Meta-analysis of outcomes of pericardial effusion
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De Filippo, Ovidio, Gatti, Paolo, Rettegno, Sara, Iannaccone, Mario, D’Ascenzo, Fabrizio, Lazaros, George, Brucato, Antonio, Tousoulis, Dimitrios, Adler, Yehuda, and Imazio, Massimo
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- 2019
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5. Beta-blocker therapy reduces mortality in patients with coronary artery disease treated with percutaneous revascularization: a meta-analysis of adjusted results
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Peyracchia, Mattia, Errigo, Daniele, Raposeiras Rubin, Sergio, Conrotto, Federico, DiNicolantonio, James J., Omedè, Pierluigi, Rettegno, Sara, Iannaccone, Mario, Moretti, Claudio, D’Amico, Maurizio, Gaita, Fiorenzo, and D’Ascenzo, Fabrizio
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- 2018
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6. Is pericardial effusion a negative prognostic marker? Meta-analysis of outcomes of pericardial effusion
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De Filippo, Ovidio Gatti, Paolo Rettegno, Sara Iannaccone, Mario D'Ascenzo, Fabrizio Lazaros, George Brucato, Antonio and Tousoulis, Dimitrios Adler, Yehuda Imazio, Massimo
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Background The prognostic relevance and the prevalence of pericardial effusion in several diseases are not well established. The aim of this meta-analysis is to summarize the available evidence related to pericardial effusion prevalence and outcomes according to the cause. Methods Articles investigating the prognosis of pericardial effusion were identified by literature search. Twenty-three studies were finally included (17 022 patients). All-cause mortality was the primary end-point. Secondary end-point was the prevalence of pericardial effusion in most common diseases related to this clinical condition. Results The pooled prevalence of pericardial effusion was 19.5% [95% confidence interval (CI): 14.3-26]. After a mean follow-up of 36 +/- 23 months, the risk of death was higher in pericardial effusion patients [hazard ratio (HR) 1.59, 95% CI 1.37-1.85, P
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- 2019
7. Comparison between functional and intravascular imaging approaches guiding percutaneous coronary intervention: A network meta‐analysis of randomized and propensity matching studies
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Iannaccone, Mario, primary, Abdirashid, Mohamed, additional, Annone, Umberto, additional, Saint‐Hilary, Gaëlle, additional, Meier, Pascal, additional, Chieffo, Alaide, additional, Chen, Sl, additional, Mario, Carlo, additional, Conrotto, Federico, additional, Omedè, Pierluigi, additional, Montefusco, Antonio, additional, De Benedictis, Michele, additional, Rettegno, Sara, additional, Doronzo, Baldassare, additional, Gasparini, Mauro, additional, Rinaldi, Mauro, additional, D'Amico, Maurizio, additional, and D'Ascenzo, Fabrizio, additional
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- 2019
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8. Improving Selection of Mitraclip Candidates in Advanced Chronic Heart Failure: Look Right to Predict Right
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Frea, Simone, primary, Crimi, Gabriele, additional, Gaemperli, Oliver, additional, Pidello, Stefano, additional, Raineri, Claudia, additional, D'Ascenzo, Fabrizio, additional, Crescio, Valeria, additional, Boretto, Paolo, additional, Gritti, Valeria, additional, Giordana, Francesca, additional, Magrini, Giulia, additional, Rettegno, Sara, additional, Gazzoli, Fabrizio, additional, Rabajoli, Alessandra, additional, Montefusco, Antonio, additional, Ferrario, Maurizio, additional, La Torre, Michele W, additional, D'Amico, Maurizio, additional, Rinaldi, Mauro, additional, Ruschitzka, Frank, additional, and Oltrona Visconti, Luigi, additional
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- 2019
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9. Impact of design of coronary stents and length of dual antiplatelet therapies on ischaemic and bleeding events: a network meta-analysis of 64 randomized controlled trials and 102 735 patients
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D'Ascenzo, Fabrizio, Iannaccone, Mario, Saint-Hilary, Gaelle, Bertaina, Maurizio, Schulz-Schüpke, Stefanie, Wahn Lee, Cheol, Chieffo, Alaide, Helft, Gerard, Gili, Sebastiano, Barbero, Umberto, Biondi Zoccai, Giuseppe, Moretti, Claudio, Ugo, Fabrizio, D'Amico, Maurizio, Garbo, Roberto, Stone, Gregg, Rettegno, Sara, Omedè, Pierluigi, Conrotto, Federico, Templin, Christian, Colombo, Antonio, Park, Seung-Jung, Kastrati, Adnan, Hildick-Smith, David, Gasparini, Mauro, Gaita, Fiorenzo, University of Zurich, and D'Ascenzo, Fabrizio
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10209 Clinic for Cardiology ,610 Medicine & health ,2705 Cardiology and Cardiovascular Medicine - Published
- 2017
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10. Comparison between functional and intravascular imaging approaches guiding percutaneous coronary intervention: A network meta‐analysis of randomized and propensity matching studies.
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Iannaccone, Mario, Abdirashid, Mohamed, Annone, Umberto, Saint‐Hilary, Gaëlle, Meier, Pascal, Chieffo, Alaide, Chen, Sl, Mario, Carlo, Conrotto, Federico, Omedè, Pierluigi, Montefusco, Antonio, De Benedictis, Michele, Rettegno, Sara, Doronzo, Baldassare, Gasparini, Mauro, Rinaldi, Mauro, D'Amico, Maurizio, and D'Ascenzo, Fabrizio
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- 2020
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11. Diagnostic accuracy of functional, imaging and biochemical tests for patients presenting with chest pain to the emergency department: A systematic review and meta-analysis
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Iannaccone, Mario, primary, Gili, Sebastiano, additional, De Filippo, Ovidio, additional, D’Amico, Salvatore, additional, Gagliardi, Marco, additional, Bertaina, Maurizio, additional, Mazzilli, Silvia, additional, Rettegno, Sara, additional, Bongiovanni, Federica, additional, Gatti, Paolo, additional, Ugo, Fabrizio, additional, Boccuzzi, Giacomo G, additional, Colangelo, Salvatore, additional, Prato, Silvia, additional, Moretti, Claudio, additional, D’Amico, Maurizio, additional, Noussan, Patrizia, additional, Garbo, Roberto, additional, Hildick-Smith, David, additional, Gaita, Fiorenzo, additional, and D’Ascenzo, Fabrizio, additional
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- 2018
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12. Impact of design of coronary stents and length of dual antiplatelet therapies on ischaemic and bleeding events: a network meta-analysis of 64 randomized controlled trials and 102 735 patients
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D’Ascenzo, Fabrizio, primary, Iannaccone, Mario, additional, Saint-Hilary, Gaelle, additional, Bertaina, Maurizio, additional, Schulz-Schüpke, Stefanie, additional, Wahn Lee, Cheol, additional, Chieffo, Alaide, additional, Helft, Gerard, additional, Gili, Sebastiano, additional, Barbero, Umberto, additional, Biondi Zoccai, Giuseppe, additional, Moretti, Claudio, additional, Ugo, Fabrizio, additional, D’Amico, Maurizio, additional, Garbo, Roberto, additional, Stone, Gregg, additional, Rettegno, Sara, additional, Omedè, Pierluigi, additional, Conrotto, Federico, additional, Templin, Christian, additional, Colombo, Antonio, additional, Park, Seung-jung, additional, Kastrati, Adnan, additional, Hildick-Smith, David, additional, Gasparini, Mauro, additional, and Gaita, Fiorenzo, additional
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- 2017
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13. Diagnostic accuracy of functional, imaging and biochemical tests for patients presenting with chest pain to the emergency department: A systematic review and meta-analysis
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Iannaccone, Mario, Gili, Sebastiano, De Filippo, Ovidio, D’Amico, Salvatore, Gagliardi, Marco, Bertaina, Maurizio, Mazzilli, Silvia, Rettegno, Sara, Bongiovanni, Federica, Gatti, Paolo, Ugo, Fabrizio, Boccuzzi, Giacomo G, Colangelo, Salvatore, Prato, Silvia, Moretti, Claudio, D’Amico, Maurizio, Noussan, Patrizia, Garbo, Roberto, Hildick-Smith, David, Gaita, Fiorenzo, and D’Ascenzo, Fabrizio
- Abstract
Background: Non-invasive ischaemia tests and biomarkers are widely adopted to rule out acute coronary syndrome in the emergency department. Their diagnostic accuracy has yet to be precisely defined.Methods: Medline, Cochrane Library CENTRAL, EMBASE and Biomed Central were systematically screened (start date 1 September 2016, end date 1 December 2016). Prospective studies (observational or randomised controlled trial) comparing functional/imaging or biochemical tests for patients presenting with chest pain to the emergency department were included.Results: Overall, 77 studies were included, for a total of 49,541 patients (mean age 59.9 years). Fast and six-hour highly sensitive troponin T protocols did not show significant differences in their ability to detect acute coronary syndromes, as they reported a sensitivity and specificity of 0.89 (95% confidence interval 0.79–0.94) and 0.84 (0.74–0.9) vs 0.89 (0.78–0.94) and 0.83 (0.70–0.92), respectively. The addition of copeptin to troponin increased sensitivity and reduced specificity, without improving diagnostic accuracy. The diagnostic value of non-invasive tests for patients without troponin increase was tested. Coronary computed tomography showed the highest level of diagnostic accuracy (sensitivity 0.93 (0.81–0.98) and specificity 0.90 (0.93–0.94)), along with myocardial perfusion scintigraphy (sensitivity 0.85 (0.77–0.91) and specificity 0.92 (0.83–0.96)). Stress echography was inferior to coronary computed tomography but non-inferior to myocardial perfusion scintigraphy, while exercise testing showed the lower level of diagnostic accuracy.Conclusions: Fast and six-hour highly sensitive troponin T protocols provide an overall similar level of diagnostic accuracy to detect acute coronary syndrome. Among the non-invasive ischaemia tests for patients without troponin increase, coronary computed tomography and myocardial perfusion scintigraphy showed the highest sensitivity and specificity.
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- 2019
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14. Impact of design of coronary stents and length of dual antiplatelet therapies on ischaemic and bleeding events: a network meta-analysis of 64 randomized controlled trials and 102 735 patients
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Pierluigi Omedè, Claudio Moretti, Antonio Colombo, Stefanie Schulz-Schüpke, Maurizio D'Amico, Alaide Chieffo, Federico Conrotto, Fabrizio Ugo, Seung-Jung Park, Sebastiano Gili, Gregg W. Stone, Maurizio Bertaina, Cheol Wahn Lee, Fabrizio D'Ascenzo, Gérard Helft, Roberto Garbo, Umberto Barbero, Sara Rettegno, Fiorenzo Gaita, Christian Templin, Giuseppe Biondi Zoccai, Adnan Kastrati, David Hildick-Smith, Mario Iannaccone, Gaelle Saint-Hilary, Mauro Gasparini, D'Ascenzo, Fabrizio, Iannaccone, Mario, Saint hilary, Gaelle, Bertaina, Maurizio, Schulz schüpke, Stefanie, Wahn Lee, Cheol, Chieffo, Alaide, Helft, Gerard, Gili, Sebastiano, Barbero, Umberto, Biondi Zoccai, Giuseppe, Moretti, Claudio, Ugo, Fabrizio, D'Amico, Maurizio, Garbo, Roberto, Stone, Gregg, Rettegno, Sara, Omedè, Pierluigi, Conrotto, Federico, Templin, Christian, Colombo, Antonio, Park, Seung jung, Kastrati, Adnan, Hildick smith, David, Gasparini, Mauro, and Gaita, Fiorenzo
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medicine.medical_specialty ,animal structures ,medicine.medical_treatment ,Myocardial Ischemia ,Hemorrhage ,Coronary Artery Disease ,030204 cardiovascular system & hematology ,Length of dual antiplatelet therapy ,Percutaneous coronary intervention ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Randomized controlled trial ,law ,Internal medicine ,Absorbable Implants ,Clinical endpoint ,medicine ,Humans ,Zotarolimus ,cardiovascular diseases ,030212 general & internal medicine ,Myocardial infarction ,Network meta-analysis ,Randomized Controlled Trials as Topic ,DAPT duration ,business.industry ,Stent ,Drug-Eluting Stents ,Network meta-analysi ,medicine.disease ,BRS DES EES ZES ,Surgery ,Meta-analysis ,Cardiology ,Drug Therapy, Combination ,Stents ,DAPT ,Cardiology and Cardiovascular Medicine ,business ,Platelet Aggregation Inhibitors ,Mace ,medicine.drug - Abstract
Aims The differential impact on ischaemic and bleeding events of the type of drug-eluting stent [durable polymer stents [DES] vs. biodegradable polymer stents vs. bioresorbable scaffolds (BRS)] and length of dual antiplatelet therapy (DAPT) remains to be defined. Methods and results Randomized controlled trials comparing different types of DES and/or DAPT durations were selected. The primary endpoint was Major Adverse Cardiovascular Events (MACE) [a composite of death, myocardial infarction (MI), and target vessel revascularization]. Definite stent thrombosis (ST) and single components of MACE were secondary endpoints. The arms of interest were: BRS with 12 months of DAPT (12mDAPT), biodegradable polymer stent with 12mDAPT, durable polymer stent [everolimus-eluting (EES), zotarolimus-eluting (ZES)] with 12mDAPT, EES/ZES with 12 months of DAPT (DAPT > 12 m). Sixty-four studies with 150 arms and 102 735 patients were included. After a median follow-up of 20 months, MACE rates were similar in the different arms of interest. EES/ZES with DAPT > 12 m reported a lower incidence of MI than the other groups, while BRS showed a higher rate of ST when compared to EES/ZES, irrespective of DAPT length. A higher risk of major bleedings was observed for DAPT > 12 m as compared to shorter DAPT. Conclusion Durable and biodegradable polymer stents along with BRS report a similar rate of MACE irrespective of DAPT length. Fewer MI are observed with EES/ZES with DAPT > 12 m, while a higher rate of ST is reported for BRS when compared to EES/ZES, independently from DAPT length. Stent type may partially affect the outcome together with DAPT length.
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- 2017
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15. Stress Echocardiography in Italian Echocardiographic Laboratories: A Survey of the Italian Society of Echocardiography and Cardiovascular Imaging.
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Ciampi Q, Pepi M, Antonini-Canterin F, Barbieri A, Barchitta A, Faganello G, Miceli S, Parato VM, Tota A, Trocino G, Abbate M, Accadia M, Alemanni R, Angelini A, Anglano F, Anselmi M, Aquila I, Aramu S, Avogadri E, Azzaro G, Badano L, Balducci A, Ballocca F, Barbarossa A, Barbati G, Barletta V, Barone D, Becherini F, Benfari G, Beraldi M, Bergandi G, Bilardo G, Binno SM, Bolognesi M, Bongiovi S, Bragato RM, Braggion G, Brancaleoni R, Bursi F, Dessalvi CC, Cameli M, Canu A, Capitelli M, Capra ACM, Carbonara R, Carbone M, Carbonella M, Carrabba N, Casavecchia G, Casula M, Chesi E, Cicco S, Citro R, Cocchia R, Colombo BM, Colonna P, Conte M, Corrado G, Cortesi P, Cortigiani L, Costantino MF, Cozza F, Cucchini U, D'Angelo M, Da Ros S, D'Andrea F, D'Andrea A, D'Auria F, De Caridi G, De Feo S, De Matteis GM, De Vecchi S, Del Giudice C, Dell'Angela L, Paoli LD, Dentamaro I, Destefanis P, Di Bella G, Di Fulvio M, Di Gaetano R, Di Giannuario G, Di Gioia A, Di Martino LFM, Di Muro C, Di Nora C, Di Salvo G, Dodi C, Dogliani S, Donati F, Dottori M, Epifani G, Fabiani I, Ferrara F, Ferrara L, Ferrua S, Filice G, Fiorino M, Forno D, Garini A, Giarratana GA, Gigantino G, Giorgi M, Giubertoni E, Greco CA, Grigolato M, Marra WG, Holzl A, Iaiza A, Iannaccone A, Ilardi F, Imbalzano E, Inciardi RM, Inserra CA, Iori E, Izzo A, La Rosa G, Labanti G, Lanzone AM, Lanzoni L, Lapetina O, Leiballi E, Librera M, Conte CL, Monaco ML, Lombardo A, Luciani M, Lusardi P, Magnante A, Malagoli A, Malatesta G, Mancusi C, Manes MT, Manganelli F, Mantovani F, Manuppelli V, Marchese V, Marinacci L, Mattioli R, Maurizio C, Mazza GA, Mazza S, Melis M, Meloni G, Merli E, Milan A, Minardi G, Monaco A, Monte I, Montresor G, Moreo A, Mori F, Morini S, Moro C, Morrone D, Negri F, Nipote C, Nisi F, Nocco S, Novello L, Nunziata L, Perini AP, Parodi A, Pasanisi EM, Pastorini G, Pavasini R, Pavoni D, Pedone C, Pelliccia F, Pelliciari G, Pelloni E, Pergola V, Perillo G, Petruccelli E, Pezzullo C, Piacentini G, Picardi E, Pinna G, Pizzarelli M, Pizzuti A, Poggi MM, Posteraro A, Privitera C, Rampazzo D, Ratti C, Rettegno S, Ricci F, Ricci C, Rolando C, Rossi S, Rovera C, Ruggieri R, Russo MG, Sacchi N, Saladino A, Sani F, Sartori C, Scarabeo V, Sciacqua A, Scillone A, Scopelliti PA, Scorza A, Scozzafava A, Serafini F, Serra W, Severino S, Simeone B, Sirico D, Solari M, Spadaro GL, Stefani L, Strangio A, Surace FC, Tamborini G, Tarquinio N, Tassone EJ, Tavarozzi I, Tchana B, Tedesco G, Tinto M, Torzillo D, Totaro A, Triolo OF, Troisi F, Tusa M, Vancheri F, Varasano V, Venezia A, Vermi AC, Villari B, Zampi G, Zannoni J, Zito C, Zugaro A, Picano E, and Carerj S
- Abstract
Background: The Italian Society of Echography and Cardiovascular Imaging (SIECVI) conducted a national survey to understand the volumes of activity, modalities and stressors used during stress echocardiography (SE) in Italy., Methods: We analyzed echocardiography laboratory activities over a month (November 2022). Data were retrieved through an electronic survey based on a structured questionnaire, uploaded on the SIECVI website., Results: Data were obtained from 228 echocardiographic laboratories, and SE examinations were performed in 179 centers (80.6%): 87 centers (47.5%) were in the northern regions of Italy, 33 centers (18.4%) were in the central regions, and 61 (34.1%) in the southern regions. We annotated a total of 4057 SE. We divided the SE centers into three groups, according to the numbers of SE performed: <10 SE (low-volume activity, 40 centers), between 10 and 39 SE (moderate volume activity, 102 centers) and ≥40 SE (high volume activity, 37 centers). Dipyridamole was used in 139 centers (77.6%); exercise in 120 centers (67.0%); dobutamine in 153 centers (85.4%); pacing in 37 centers (21.1%); and adenosine in 7 centers (4.0%). We found a significant difference between the stressors used and volume of activity of the centers, with a progressive increase in the prevalence of number of stressors from low to high volume activity ( P = 0.033). The traditional evaluation of regional wall motion of the left ventricle was performed in all centers, with combined assessment of coronary flow velocity reserve (CFVR) in 90 centers (50.3%): there was a significant difference in the centers with different volume of SE activity: the incidence of analysis of CFVR was significantly higher in high volume centers compared to low - moderate - volume (32.5%, 41.0% and 73.0%, respectively, P < 0.001). The lung ultrasound (LUS) was assessed in 67 centers (37.4%). Furthermore for LUS, we found a significant difference in the centers with different volume of SE activity: significantly higher in high volume centers compared to low - moderate - volume (25.0%, 35.3% and 56.8%, respectively, P < 0.001)., Conclusions: This nationwide survey demonstrated that SE was significantly widespread and practiced throughout Italy. In addition to the traditional indication to coronary artery disease based on regional wall motion analysis, other indications are emerging with an increase in the use of LUS and CFVR, especially in high-volume centers., Competing Interests: There are no conflicts of interest., (Copyright: © 2023 Journal of Cardiovascular Echography.)
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- 2023
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16. Organization and Activity of Italian Echocardiographic Laboratories: A Survey of the Italian Society of Echocardiography and Cardiovascular Imaging.
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Ciampi Q, Pepi M, Antonini-Canterin F, Barbieri A, Barchitta A, Faganello G, Miceli S, Parato VM, Tota A, Trocino G, Abbate M, Accadia M, Alemanni R, Angelini A, Anglano F, Anselmi M, Aquila I, Aramu S, Avogadri E, Azzaro G, Badano L, Balducci A, Ballocca F, Barbarossa A, Barbati G, Barletta V, Barone D, Becherini F, Benfari G, Beraldi M, Bergandi G, Bilardo G, Binno SM, Bolognesi M, Bongiovi S, Bragato RM, Braggion G, Brancaleoni R, Bursi F, Dessalvi CC, Cameli M, Canu A, Capitelli M, Capra ACM, Carbonara R, Carbone M, Carbonella M, Carrabba N, Casavecchia G, Casula M, Chesi E, Cicco S, Citro R, Cocchia R, Colombo BM, Colonna P, Conte M, Corrado G, Cortesi P, Cortigiani L, Costantino MF, Cozza F, Cucchini U, D'Angelo M, Ros SD, D'Andrea F, D'Andrea A, D'Auria F, De Caridi G, De Feo S, De Matteis GM, De Vecchi S, Giudice CD, Dell'Angela L, Paoli LD, Dentamaro I, Destefanis P, Di Fulvio M, Di Gaetano R, Di Giannuario G, Di Gioia A, Di Martino LFM, Di Muro C, Di Nora C, Di Salvo G, Dodi C, Dogliani S, Donati F, Dottori M, Epifani G, Fabiani I, Ferrara F, Ferrara L, Ferrua S, Filice G, Fiorino M, Forno D, Garini A, Giarratana GA, Gigantino G, Giorgi M, Giubertoni E, Greco CA, Grigolato M, Marra WG, Holzl A, Iaiza A, Iannaccone A, Ilardi F, Imbalzano E, Inciardi R, Inserra CA, Iori E, Izzo A, Rosa G, Labanti G, Lanzone AM, Lanzoni L, Lapetina O, Leiballi E, Librera M, Conte CL, Monaco ML, Lombardo A, Luciani M, Lusardi P, Magnante A, Malagoli A, Malatesta G, Mancusi C, Manes MT, Manganelli F, Mantovani F, Manuppelli V, Marchese V, Marinacci L, Mattioli R, Maurizio C, Mazza GA, Mazza S, Melis M, Meloni G, Merli E, Milan A, Minardi G, Monaco A, Monte I, Montresor G, Moreo A, Mori F, Morini S, Moro C, Morrone D, Negri F, Nipote C, Nisi F, Nocco S, Novello L, Nunziata L, Perini AP, Parodi A, Pasanisi EM, Pastorini G, Pavasini R, Pavoni D, Pedone C, Pelliccia F, Pelliciari G, Pelloni E, Pergola V, Perillo G, Petruccelli E, Pezzullo C, Piacentini G, Picardi E, Pinna G, Pizzarelli M, Pizzuti A, Poggi MM, Posteraro A, Privitera C, Rampazzo D, Ratti C, Rettegno S, Ricci F, Ricci C, Rolando C, Rossi S, Rovera C, Ruggieri R, Russo MG, Sacchi N, Saladino A, Sani F, Sartori C, Scarabeo V, Sciacqua A, Scillone A, Scopelliti PA, Scorza A, Scozzafava A, Serafini F, Serra W, Severino S, Simeone B, Sirico D, Solari M, Spadaro GL, Stefani L, Strangio A, Surace FC, Tamborini G, Tarquinio N, Tassone EJ, Tavarozzi I, Tchana B, Tedesco G, Tinto M, Torzillo D, Totaro A, Triolo OF, Troisi F, Tusa M, Vancheri F, Varasano V, Venezia A, Vermi AC, Villari B, Zampi G, Zannoni J, Zito C, Zugaro A, Di Bella G, and Carerj S
- Abstract
Background: The Italian Society of Echocardiography and Cardiovascular Imaging (SIECVI) conducted a national survey to understand better how different echocardiographic modalities are used and accessed in Italy., Methods: We analyzed echocardiography laboratory activities over a month (November 2022). Data were retrieved via an electronic survey based on a structured questionnaire, uploaded on the SIECVI website., Results: Data were obtained from 228 echocardiographic laboratories: 112 centers (49%) in the northern, 43 centers (19%) in the central, and 73 (32%) in the southern regions. During the month of observation, we collected 101,050 transthoracic echocardiography (TTE) examinations performed in all centers. As concern other modalities there were performed 5497 transesophageal echocardiography (TEE) examinations in 161/228 centers (71%); 4057 stress echocardiography (SE) examinations in 179/228 centers (79%); and examinations with ultrasound contrast agents (UCAs) in 151/228 centers (66%). We did not find significant regional variations between the different modalities. The usage of picture archiving and communication system (PACS) was significantly higher in the northern (84%) versus central (49%) and southern (45%) centers ( P < 0.001). Lung ultrasound (LUS) was performed in 154 centers (66%), without difference between cardiology and noncardiology centers. The evaluation of left ventricular (LV) ejection fraction was evaluated mainly using the qualitative method in 223 centers (94%), occasionally with the Simpson method in 193 centers (85%), and with selective use of the three-dimensional (3D) method in only 23 centers (10%). 3D TTE was present in 137 centers (70%), and 3D TEE in all centers where TEE was done (71%). The assessment of LV diastolic function was done routinely in 80% of the centers. Right ventricular function was evaluated using tricuspid annular plane systolic excursion in all centers, using tricuspid valve annular systolic velocity by tissue Doppler imaging in 53% of the centers, and using fractional area change in 33% of the centers. When we divided into cardiology (179, 78%) and noncardiology (49, 22%) centers, we found significant differences in the SE (93% vs. 26%, P < 0.001), TEE (85% vs. 18%), UCA (67% vs. 43%, P < 0001), and STE (87% vs. 20%, P < 0.001). The incidence of LUS evaluation was similar between the cardiology and noncardiology centers (69% vs. 61%, P = NS)., Conclusions: This nationwide survey demonstrated that digital infrastructures and advanced echocardiography modalities, such as 3D and STE, are widely available in Italy with a notable diffuse uptake of LUS in the core TTE examination, a suboptimal diffusion of PACS recording, and conservative use of UCA, 3D, and strain. There are significant differences between northern and central-southern regions and echocardiographic laboratories that pertain to the cardiac unit. This inhomogeneous distribution of technology represents one of the main issues that must be solved to standardize the practice of echocardiography., Competing Interests: There are no conflicts of interest., (Copyright: © 2023 Journal of Cardiovascular Echography.)
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- 2023
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17. Diagnostic accuracy of functional, imaging and biochemical tests for patients presenting with chest pain to the emergency department: A systematic review and meta-analysis.
- Author
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Iannaccone M, Gili S, De Filippo O, D'Amico S, Gagliardi M, Bertaina M, Mazzilli S, Rettegno S, Bongiovanni F, Gatti P, Ugo F, Boccuzzi GG, Colangelo S, Prato S, Moretti C, D'Amico M, Noussan P, Garbo R, Hildick-Smith D, Gaita F, and D'Ascenzo F
- Subjects
- Acute Coronary Syndrome diagnostic imaging, Biomarkers blood, Chest Pain diagnostic imaging, Echocardiography, Stress methods, Emergency Service, Hospital, Exercise Test methods, Female, Glycopeptides blood, Humans, Male, Middle Aged, Prospective Studies, Radionuclide Imaging methods, Sensitivity and Specificity, Troponin T blood, Acute Coronary Syndrome blood, Chest Pain blood, Coronary Vessels diagnostic imaging, Myocardial Perfusion Imaging methods, Tomography, X-Ray Computed methods
- Abstract
Background: Non-invasive ischaemia tests and biomarkers are widely adopted to rule out acute coronary syndrome in the emergency department. Their diagnostic accuracy has yet to be precisely defined., Methods: Medline, Cochrane Library CENTRAL, EMBASE and Biomed Central were systematically screened (start date 1 September 2016, end date 1 December 2016). Prospective studies (observational or randomised controlled trial) comparing functional/imaging or biochemical tests for patients presenting with chest pain to the emergency department were included., Results: Overall, 77 studies were included, for a total of 49,541 patients (mean age 59.9 years). Fast and six-hour highly sensitive troponin T protocols did not show significant differences in their ability to detect acute coronary syndromes, as they reported a sensitivity and specificity of 0.89 (95% confidence interval 0.79-0.94) and 0.84 (0.74-0.9) vs 0.89 (0.78-0.94) and 0.83 (0.70-0.92), respectively. The addition of copeptin to troponin increased sensitivity and reduced specificity, without improving diagnostic accuracy. The diagnostic value of non-invasive tests for patients without troponin increase was tested. Coronary computed tomography showed the highest level of diagnostic accuracy (sensitivity 0.93 (0.81-0.98) and specificity 0.90 (0.93-0.94)), along with myocardial perfusion scintigraphy (sensitivity 0.85 (0.77-0.91) and specificity 0.92 (0.83-0.96)). Stress echography was inferior to coronary computed tomography but non-inferior to myocardial perfusion scintigraphy, while exercise testing showed the lower level of diagnostic accuracy., Conclusions: Fast and six-hour highly sensitive troponin T protocols provide an overall similar level of diagnostic accuracy to detect acute coronary syndrome. Among the non-invasive ischaemia tests for patients without troponin increase, coronary computed tomography and myocardial perfusion scintigraphy showed the highest sensitivity and specificity.
- Published
- 2019
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