13 results on '"Rettig, Ingo"'
Search Results
2. Mitotic figure in the peripheral blood smear
- Author
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Hörber, Sebastian, Rettig, Ingo, and Peter, Andreas
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- 2018
- Full Text
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3. Diabetische Nephropathie
- Author
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Wolf, Sabine, primary and Rettig, Ingo, additional
- Published
- 2008
- Full Text
- View/download PDF
4. Malformations in a cohort of 284 women with Mayer-Rokitansky-Küster-Hauser syndrome (MRKH)
- Author
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Oppelt Patricia G, Lermann Johannes, Strick Reiner, Dittrich Ralf, Strissel Pamela, Rettig Ingo, Schulze Christine, Renner Stefan P, Beckmann Matthias W, Brucker Sara, Rall Katharina, and Mueller Andreas
- Subjects
MRKH syndrome ,Diagnosis ,Staging ,Malformations ,VCUAM ,Renal abnormalities ,Gynecology and obstetrics ,RG1-991 ,Reproduction ,QH471-489 - Abstract
Abstract Background The aim of this retrospective study was to describe the spectrum of genital and associated malformations in women with Mayer-Rokitansky-Küster-Hauser syndrome using evaluated diagnostic procedures and the Vagina Cervix Uterus Adnex – associated Malformation classification system (VCUAM). Methods 290 women with MRKH syndrome were clinically evaluated with using clinical examinations, abdominal and perineal/rectal ultrasound, MRI, and laparoscopy. Results Classification of female genital malformation according to the Vagina Cervix Uterus Adnex – associated Malformation classification system was possible in 284 women (97.9%). Complete atresia of Vagina (V5b) and bilateral atresia of Cervix (C2b) were found in 284 patients (100%). Uterus: bilateral rudimentary or a plastic uterine horns were found in 239 women (84.2%). Adnexa: normal Adnexa were found in 248 women (87.3%). Malformations: associated malformations were found in 126 of 282 evaluable women (44.7%), 84 women (29.6%) had malformations of the renal system. Of 284 women with Mayer-Rokitansky-Küster-Hauser syndrome 212 women (74.7%) could be classified as V5bC2bU4bA0. The most frequent classification was V5bC2bU4bA0M0 (46.8%) diagnosed in 133 of 284 women. Conclusions Complete atresia of vagina and cervix were found in all patients, variable malformations were found with uterus and adnexa. A variety of associated malformations were present, predominantly of the renal system. It is therefore recommended that all patients with genital malformations should be evaluated for renal abnormalities.
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- 2012
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- View/download PDF
5. Sex-Specific Associations of Testosterone With Metabolic Traits
- Author
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Lutz, Stefan Z., primary, Wagner, Robert, additional, Fritsche, Louise, additional, Peter, Andreas, additional, Rettig, Ingo, additional, Willmann, Caroline, additional, Fehlert, Ellen, additional, Martus, Peter, additional, Todenhöfer, Tilman, additional, Stefan, Norbert, additional, Fritsche, Andreas, additional, Häring, Hans-Ulrich, additional, and Heni, Martin, additional
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- 2019
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- View/download PDF
6. Mitotic figure in the peripheral blood smear
- Author
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Hörber, Sebastian, primary, Rettig, Ingo, additional, and Peter, Andreas, additional
- Published
- 2017
- Full Text
- View/download PDF
7. Malformations in a cohort of 284 women with Mayer-Rokitansky-Küster-Hauser syndrome (MRKH)
- Author
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Oppelt, Patricia G, Lermann, Johannes, Strick, Reiner, Dittrich, Ralf, Strissel, Pamela, Rettig, Ingo, Schulze, Christine, Renner, Stefan P, Beckmann, Matthias W, Brucker, Sara, Rall, Katharina, and Mueller, Andreas
- Subjects
Adult ,Staging ,VCUAM ,46, XX Disorders of Sex Development ,Adolescent ,lcsh:QH471-489 ,Medizinische Fakultät -ohne weitere Spezifikation ,Kidney ,lcsh:Gynecology and obstetrics ,Congenital Abnormalities ,MRKH syndrome ,Renal abnormalities ,Endocrinology ,Diagnosis ,Humans ,lcsh:Reproduction ,Abnormalities, Multiple ,ddc:610 ,Mullerian Ducts ,lcsh:RG1-991 ,Retrospective Studies ,Ultrasonography ,Research ,Uterus ,Spine ,Reproductive Medicine ,Somites ,Vagina ,Malformations ,Female ,Developmental Biology - Abstract
Background The aim of this retrospective study was to describe the spectrum of genital and associated malformations in women with Mayer-Rokitansky-Küster-Hauser syndrome using evaluated diagnostic procedures and the Vagina Cervix Uterus Adnex – associated Malformation classification system (VCUAM). Methods 290 women with MRKH syndrome were clinically evaluated with using clinical examinations, abdominal and perineal/rectal ultrasound, MRI, and laparoscopy. Results Classification of female genital malformation according to the Vagina Cervix Uterus Adnex – associated Malformation classification system was possible in 284 women (97.9%). Complete atresia of Vagina (V5b) and bilateral atresia of Cervix (C2b) were found in 284 patients (100%). Uterus: bilateral rudimentary or a plastic uterine horns were found in 239 women (84.2%). Adnexa: normal Adnexa were found in 248 women (87.3%). Malformations: associated malformations were found in 126 of 282 evaluable women (44.7%), 84 women (29.6%) had malformations of the renal system. Of 284 women with Mayer-Rokitansky-Küster-Hauser syndrome 212 women (74.7%) could be classified as V5bC2bU4bA0. The most frequent classification was V5bC2bU4bA0M0 (46.8%) diagnosed in 133 of 284 women. Conclusions Complete atresia of vagina and cervix were found in all patients, variable malformations were found with uterus and adnexa. A variety of associated malformations were present, predominantly of the renal system. It is therefore recommended that all patients with genital malformations should be evaluated for renal abnormalities.
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- 2012
8. Comparison of the Diagnostic Performance of Three Natriuretic Peptides in Hemodialysis Patients: Which is the Appropriate Biomarker?
- Author
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Artunc, Ferruh, primary, Mueller, Christian, additional, Breidthardt, Tobias, additional, Twerenbold, Raphael, additional, Rettig, Ingo, additional, Usta, Engin, additional, Häring, Hans-Ulrich, additional, and Friedrich, Björn, additional
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- 2012
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9. Vaginale Blutung als Symptom eines internistischen Notfalls - Tücken der Therapie mit neuen oralen Antikoagulanzien.
- Author
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Baumann, Dorothea, Haap, Michael, Tsaousidis, Christos, Krämer, Bernhard, Schreieck, Jürgen, Jaschonek, Karl, Rettig, Ingo, Peter, Andreas, Wallwiener, Diethelm, and Artunc, Ferruh
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- 2014
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10. Comparison of the Diagnostic Performance of Three Natriuretic Peptides in Hemodialysis Patients: Which is the Appropriate Biomarker?
- Author
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Artunc, Ferruh, Mueller, Christian, Breidthardt, Tobias, Twerenbold, Raphael, Rettig, Ingo, Usta, Engin, Häring, Hans-Ulrich, and Friedrich, Björn
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NATRIURETIC peptides ,HEMODIALYSIS ,HEART diseases ,BLOOD plasma ,DIURESIS - Abstract
Background: Plasma concentrations of natriuretic peptides are often elevated in chronic hemodialysis patients and difficult to interpret due to accumulation, high incidence of cardiac disease and changes in volume status. Mid-regional pro-ANP is a newly developed assay whereas BNP and its fragment NT-pro-BNP are available for a longer time. In this cross-sectional study, we compared the plasma concentration of MR-pro-ANP, BNP and NT-pro-BNP in stable ambulatory hemodialysis patients (n = 239) and investigated their associations with clinical factors such as residual diuresis, cardiac status and interdialytic weight gain and with mortality. Methods and Results: In all patients enrolled, the plasma concentration of all natriuretic peptides were largely elevated with a median concentration of 337 pg/ml (interquartile range 146-684) for BNP, 4435 pg/ml (1687-16228) for NT-proBNP and 907 pmol/L (650-1298) for MR-pro-ANP. Plasma concentration of all natriuretic peptides correlated independently with age, degree of systolic dysfunction and negatively with residual diuresis. Dependency on residual renal clearance was strongest for the fragments MR-pro-ANP and NT-pro-BNP. The plasma concentration of all natriuretic peptides was associated with mortality within 2 years of follow-up. Receiver-operated curves revealed a low sensitivity (32-45%), but high specificity for all natriuretic peptides (85-93%) resulting in a high negative predictive (82-87%). Best cut-off values obtained from were 18 611 pg/ml for NT-pro-BNP, 958 pg/ml for BNP and 1684 pmol/L for MR-pro-ANP. Conclusions: In hemodialysis patients, the fragments NTproBNP and MR-pro-ANP are largely elevated compared to BNP which is explained by accumulation. The prognostic performance of MR-pro-ANP is similar to that of NT-pro-BNP or BNP. Copyright © 2012 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]
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- 2013
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11. [Vaginal bleeding as symptom of a medical emergency--pitfalls of therapy with new oral anticoagulants - case 5/2014].
- Author
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Baumann D, Haap M, Tsaousidis C, Krämer B, Schreieck J, Jaschonek K, Rettig I, Peter A, Wallwiener D, and Artunc F
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- Aged, 80 and over, Antithrombins pharmacokinetics, Antithrombins therapeutic use, Benzimidazoles pharmacokinetics, Benzimidazoles therapeutic use, Dabigatran, Diagnosis, Differential, Emergencies, Female, Humans, Kidney Failure, Chronic complications, Metabolic Clearance Rate physiology, beta-Alanine adverse effects, beta-Alanine pharmacokinetics, beta-Alanine therapeutic use, Antithrombins adverse effects, Benzimidazoles adverse effects, Uterine Hemorrhage chemically induced, beta-Alanine analogs & derivatives
- Abstract
History and Admission Findings: A 90-year-old female patient treated with dabigatran for atrial fibrillation presented emergently with a spontaneous vaginal bleeding due to endometrium carcinoma., Investigations: Laboratory analysis revealed azotemia consistent with acute-on-chronic renal failure. Coagulation was deranged (prolongation of activated partial thromboplastin time (aPTT) by 3.5-fold, international normalized ratio (INR) 7.8) due to a massive accumulation of dabigatran (measured plasma concentration 2230 ng/ml)., Diagnosis, Treatment and Course: Vaginal bleedings were treated with external tamponade. Hemodialysis treatment was commenced due to uremia and dabigatran accumulation. Over night, the patient was dialysed with a SLED (sustained low efficiency dialysis) regimen. After volume resuscitation renal function promptly ensued indicating prerenal azotemia as a cause of renal failure. After two more hemodialysis sessions dabigatran concentrations were no longer detecable and this was paralleled by normalization of coagulation tests., Conclusions: Dabigatran can accumulate massively during acute renal failure and evoke a life-threatening bleeding diathesis. Dabigatran can be removed with low efficient dialysis (such as SLED)., (© Georg Thieme Verlag KG Stuttgart · New York.)
- Published
- 2014
- Full Text
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12. [Two patients with renal medullary hyperechogenicity].
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Celebi N, Georges G, Machicao F, Artunc F, and Rettig I
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- 25-Hydroxyvitamin D3 1-alpha-Hydroxylase blood, Calcium blood, DNA Mutational Analysis, Diagnosis, Differential, Female, Humans, Hydroxychloroquine therapeutic use, Immunosuppressive Agents therapeutic use, Kidney Function Tests, Nephrocalcinosis blood, Nephrocalcinosis drug therapy, Nephrocalcinosis genetics, Nephrolithiasis blood, Nephrolithiasis drug therapy, Nephrolithiasis genetics, Parathyroid Hormone blood, Prednisolone therapeutic use, Receptors, Calcium-Sensing genetics, Ultrasonography, Vitamin D analogs & derivatives, Vitamin D blood, Kidney Medulla diagnostic imaging, Nephrocalcinosis diagnostic imaging, Nephrolithiasis diagnostic imaging
- Abstract
History and Admission Findings: We report two patients with medullary nephrocalcinosis and nephrolithiasis. The first patients had unspecific symptoms of a systemic inflammatory disease, the second patient was asymptomatic., Investigations: Both patients had normocalcemia and normal parathyroid hormone levels, very high 1,25(OH)(2)-vitamin D and normal to low 25-OH-vitamin D levels. On renal ultrasound, both patients displayed nephrocalcinosis and nephrolithiasis., Diagnosis: Both patients showed dysregulation of the 1α-hydroxylase activity. The first patient suffered from a systemic inflammatory disease with consecutive activation of macrophages with extrarenal α-hydroxylase activity. The second patient had a "loss of function" mutation of the calcium sensing receptor with - for the situation - inadequatly high parathyroid hormone levels and consequently a renal dysregulation of the 1α-hydroxylase., Treatment and Course: After immunosuppressive treatment with prednisolone and hydroxychloroquin there was complete remission of the systemic inflammatory disease in the first patient. In consequence the 1,25-(OH)(2)-vitamin D levels regressed and renal function stabilized. The second patient was completely asymptomatic with normal renal function, so far we did not initiate any treatment., Conclusions: Nephrocalcinosis and nephrolithiasis can result from hypercalciuria due to dysregulated hydroxylation of vitamin D. For both renal and extrarenal sources causal treatment is available., (© Georg Thieme Verlag KG Stuttgart · New York.)
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- 2012
- Full Text
- View/download PDF
13. [Rare cause of insufficient metabolic control of diabetes mellitus - Case 10/2011].
- Author
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Dudziak K, Rettig I, Adam P, Horger M, Neumann H, and Müssig K
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- Adrenal Gland Neoplasms complications, Adrenal Gland Neoplasms metabolism, Adrenal Gland Neoplasms surgery, Adrenalectomy, Cushing Syndrome complications, Cushing Syndrome diagnosis, Cushing Syndrome surgery, Diabetes Mellitus, Type 2 complications, Exenatide, Humans, Male, Metformin therapeutic use, Middle Aged, Peptides therapeutic use, Pheochromocytoma complications, Pheochromocytoma metabolism, Pheochromocytoma surgery, Tomography, Emission-Computed, Single-Photon, Venoms therapeutic use, Adrenal Gland Neoplasms diagnosis, Adrenocorticotropic Hormone metabolism, Diabetes Mellitus, Type 2 drug therapy, Hypoglycemic Agents therapeutic use, Pheochromocytoma diagnosis
- Abstract
History and Admission Findings: A 48-year-old patient presented with an insufficient control of his diabetes mellitus which was known since 3 years. The antidiabetic medication comprised metformin and exenatide., Investigations: Physical examination revealed, beside elevated blood pressure, abdominal purple striae. Endocrine testing was consistent with ectopic Cushing's syndrome. Abdominal CT showed a 5 cm measuring, inhomogeneous, contrast-enhanced mass in the right suprarenal area which was positive on iodine-131 MIBG SPECT. Furthermore, urinary catecholamines were markedly increased., Diagnosis, Treatment and Course: Diagnosis of an ACTH-producing pheochromocytoma was made and an open adrenalectomy was performed. Histology confirmed a pheochromocytoma with potential aggressive clinical behaviour according to the Pheocromocytoma of the Adrenal gland Scaled Score. 6 months after the intervention, glucose control was significantly improved with an HbA1c of 5.5%., Conclusions: An ACTH-producing pheochromocytoma is a very rare cause of deterioration of glucose control. However, in presence of typical clinical findings an endocrine work-up is warranted.
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- 2011
- Full Text
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