189 results on '"Riachi, Ghassan"'
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2. Classification of PRSS1 variants responsible for chronic pancreatitis: An expert perspective from the Franco-Chinese GREPAN Study Group
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Abrantes, Amandine, Aguilera Munoz, Lina, Albouys, Jérémie, Alric, Laurent, Amiot, Xavier, Archambeaud, Isabelle, Audiau, Solène, Bastide, Laetitia, Baudon, Julien, Bellaiche, Guy, Bellon, Serge, Bertrand, Valérie, Bideau, Karine, Billiemaz, Kareen, Billioud, Claire, Bonnefoy, Sabine, Borderon, Corinne, Bournet, Barbara, Breton, Estelle, Brugel, Mathias, Buscail, Louis, Cadiot, Guillaume, Camus, Marine, Causse, Xavier, Chamouard, Patrick, Chaput, Ulriikka, Cholet, Franck, Ciocan, Dragos Marius, Clavel, Christine, Coffin, Benoit, Coimet-Berger, Laura, Creveaux, Isabelle, Culetto, Adrian, Daboussi, Oussama, De Mestier, Louis, Degand, Thibault, D'Engremont, Christelle, Denis, Bernard, Dermine, Solène, Desgrippes, Romain, Drouet D'Aubigny, Augustin, Enaud, Raphaël, Fabre, Alexandre, Gargot, Dany, Gelsi, Eve, Gentilcore, Elena, Gincul, Rodica, Ginglinger-Favre, Emmanuelle, Giovannini, Marc, Gomercic, Cécile, Gondran, Hannah, Grainville, Thomas, Grandval, Philippe, Grasset, Denis, Grimaldi, Stéphane, Grimbert, Sylvie, Hagege, Hervé, Heissat, Sophie, Hentic, Olivia, Herber-Mayne, Anne, Hervouet, Marc, Hoibian, Solene, Jacques, Jérémie, Jais, Bénédicte, Kaassis, Mehdi, Koch, Stéphane, Lacaze, Elodie, Lacroute, Joël, Lamireau, Thierry, Laurent, Lucie, Le Guillou, Xavier, Le Rhun, Marc, Leblanc, Sarah, Levy, Philippe, Lievre, Astrid, Lorenzo, Diane, Maire, Frédérique, Marcel, Kévin, Matias, Clément, Mauillon, Jacques, Morgant, Stéphanie, Moussata, Driffa, Muller, Nelly, Nambot, Sophie, Napoleon, Bertrand, Olivier, Anne, Pagenault, Maël, Pelletier, Anne-laure, Pennec, Olivier, Pinard, Fabien, Pioche, Mathieu, Prost, Bénédicte, Queneherve, Lucille, Rebours, Vinciane, Reboux, Noemi, Rekik, Samia, Riachi, Ghassan, Rohmer, Barbara, Roquelaure, Bertrand, Rosa Hezode, Isabelle, Rostain, Florian, Saurin, Jean-Christophe, Servais, Laure, Stan-Iuga, Roxana, Subtil, Clément, Texier, Charles, Thomassin, Lucie, Tougeron, David, Tsakiris, Laurent, Valats, Jean-Christophe, Vuitton, Lucine, Wallenhorst, Timothée, Wangerme, Marc, Zanaldi, Hélène, Zerbib, Frank, Bai, Chen-Guang, Bian, Yun, Cai, Zhen-Zhai, Chang, Xiao-Yan, Chen, Guo-Dong, Cheng, Li, Chen, Yu, Guo, Jin-Tao, Guo, Tao, Han, Jun-Ling, He, Chao-Hui, Hu, Liang-Hao, Huang, Hao-Jie, Huang, Li, Huang, Li-Ya, Huang, Si-Lin, Huang, Wei, Jiang, Fei, Jiang, Hui, Lu, Feng-Chun, Lu, Guo-Tao, Lu, Zi-Peng, Li, Hui-Ping, Li, Jing, Li, Le, Li, Qiang, Li, Xiao-Yu, Lin, Qing, Lin, Yu-Li, Liu, Gai-Fang, Liu, Jie-Min, Liu, Li-Xin, Liu, Pi, Liu, Yi-Pin, Lu, Dong, Shao, Xiao-Dong, Shao, Zhuo, Song, Xu-Rui, Wang, Lei, Wang, Li-Juan, Wang, Li-Sheng, Wang, Lin, Wang, Wei, Wang, Zheng, Wen, Li, Wu, Xi, Xin, Lei, Xue, Jing, Yang, Hong, Yang, Jian-Feng, Yin, Tao, Zhang, Bei-Ping, Zhang, Guo-Wei, Zhang, Hong, Zhang, Rong-Chun, Zhao, Yi-Jun, Zhou, Si-Si, Zhu, Ke-Xiang, Masson, Emmanuelle, Zou, Wen-Bin, Pu, Na, Génin, Emmanuelle, Wu, Hao, Lin, Jin-Huan, Wang, Yuan-Chen, Li, Zhao-Shen, Cooper, David N., Férec, Claude, Liao, Zhuan, and Chen, Jian-Min
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- 2023
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3. Integrating genetic variants into clinical models for hepatocellular carcinoma risk stratification in cirrhosis
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Nahon, Pierre, Asselah, Tarik, Guyader, Dominique, Pol, Stanislas, Fontaine, Hélène, Pageaux, Georges-Philippe, De Lédinghen, Victor, Ouzan, Denis, Zoulim, Fabien, Roulot, Dominique, Tran, Albert, Bronowicki, Jean-Pierre, Decaensi, Thomas, Riachi, Ghassan, Calès, Paul, Péron, Jean-Marie, Alric, Laurent, Bourlière, Marc, Mathurin, Philippe, Dharancy, Sebastien, Blanc, Jean-Frédéric, Abergel, Armand, Chazouillères, Olivier, Mallat, Ariane, Grangé, Jean-Didier, Attali, Pierre, Louis d’Alteroche, Wartelle, Claire, Dao, Thông, Thabut, Dominique, Pilette, Christophe, Silvain, Christine, Christidis, Christos, Nguyen-Khac, Eric, Bernard-Chabert, Brigitte, Hillaire, Sophie, Di Martino, Vincent, Ganne-Carrié, Nathalie, Chaffaut, Cendrine, Archambeaud, Isabelle, d’Alteroche, Louis, Oberti, Frédéric, Moreno, Christophe, Louvet, Alexandre, Moirand, Romain, Goria, Odile, Carbonell, Nicolas, Duclos-Vallée, Jean-Charles, de Ledinghen, Victor, Ozenne, Violaine, Henrion, Jean, Perlemuter, Gabriel, Amiot, Xavier, Zarski, Jean-Pierre, Chevret, Sylvie, Bamba-Funck, Jessica, Layese, Richard, Trépo, Eric, Zucman-Rossi, Jessica, Cagnot, Carole, Guyot, Erwan, Ziol, Marianne, Sutton, Angela, and Audureau, Etienne
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- 2023
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4. THU-466 Treatment with Atezolizumab-Bevacizumab for hepatocellular carcinoma in the french population outside clinical trials: data from the prospective CHIEF cohort
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Allaire, Manon, primary, Hajer, Ben Khadhra, additional, Amaddeo, Giuliana, additional, Bouattour, Mohamed, additional, Brusset, Bleuenn, additional, Ziol, Marianne, additional, Merle, Philippe, additional, Blanc, Jean-Frédéric, additional, Uguen, Thomas, additional, Ganne-Carrié, Nathalie, additional, Cattan, Stéphane, additional, Riachi, Ghassan, additional, Loustaud-Ratti, Veronique, additional, Decaens, Thomas, additional, Silvain, Christine, additional, Peron, Jean Marie, additional, Baron, Aurore, additional, Pageaux, Georges-Philippe, additional, Oberti, Frédéric, additional, Anty, Rodolphe, additional, Manfredi, Sylvain, additional, Bourliere, Marc, additional, Ben Merabet, Yasmina, additional, Nousbaum, JeanB-aptiste, additional, Heurgue-Berlot, Alexandra, additional, Ollivier-Hourmand, Isabelle, additional, Ducournau, Gerard, additional, Ganry, Olivier, additional, Costentin, Charlotte, additional, and Khac, Eric Nguyen, additional
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- 2024
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5. OS-097 Effect of rifaximin in severe cirrhotic patients with ascites: a double-blind randomized placebo-controlled phase 3 trial
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Thévenot, Thierry, primary, Elkrief, Laure, additional, Bureau, Christophe, additional, Bardou-Jacquet, Edouard, additional, Rosa, Isabelle, additional, Khac, Eric Nguyen, additional, Oberti, Frédéric, additional, Pitta, Anais, additional, Mallet, Maxime, additional, Lebosse, Fanny, additional, Louvet, Alexandre, additional, Meunier, Lucy, additional, Nahon, Pierre, additional, Ollivier-Hourmand, Isabelle, additional, Anty, Rodolphe, additional, Francoz, Claire, additional, Riachi, Ghassan, additional, Meunier, Alexandre, additional, Tio, Gregory, additional, Muller, Allison, additional, Curé-Martin, Audace, additional, Hocquet, Didier, additional, Di Martino, Vincent, additional, Weil-Verhoeven, Delphine, additional, and Desmarets, Maxime, additional
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- 2024
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6. Clinical outcomes after treatment with direct antiviral agents: beyond the virological response in patients with previous HCV-related decompensated cirrhosis
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Pageaux, Georges-Philippe, Nzinga, Clovis Lusivika, Ganne, Nathalie, Samuel, Didier, Dorival, Céline, Zoulim, Fabien, Cagnot, Carole, Decaens, Thomas, Thabut, Dominique, Asselah, Tarik, Mathurin, Philippe, Habersetzer, François, Bronowicki, Jean-Pierre, Guyader, Dominique, Rosa, Isabelle, Leroy, Vincent, Chazouilleres, Olivier, de Ledinghen, Victor, Bourliere, Marc, Causse, Xavier, Cales, Paul, Metivier, Sophie, Loustaud-Ratti, Véronique, Riachi, Ghassan, Alric, Laurent, Gelu-Simeon, Moana, Minello, Anne, Gournay, Jérôme, Geist, Claire, Tran, Albert, Abergel, Armand, Portal, Isabelle, d’Alteroche, Louis, Raffi, François, Fontaine, Hélène, Carrat, Fabrice, and Pol, Stanislas
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- 2022
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7. Early hepatocellular carcinoma detection using magnetic resonance imaging is cost-effective in high-risk patients with cirrhosis
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Nahon, Pierre, Asselah, Tarik, Guyader, Dominique, Pol, Stanislas, Fontaine, Hélène, Pageaux, Georges-Philippe, De Lédinghen, Victor, Ouzan, Denis, Zoulim, Fabien, Roulot, Dominique, Tran, Albert, Bronowicki, Jean-Pierre, Decaensi, Thomas, Riachi, Ghassan, Calès, Paul, Péron, Jean-Marie, Alric, Laurent, Bourlière, Marc, Mathurin, Philippe, Dharancy, Sebastien, Blanc, Jean-Frédéric, Abergel, Armand, Chazouillères, Olivier, Mallat, Ariane, Grangé, Jean-Didier, Attali, Pierre, d’Alteroche, Louis, Wartelle, Claire, Dao, Thông, Thabut, Dominique, Pilette, Christophe, Silvain, Christine, Christidis, Christos, Nguyen-Khac, Eric, Bernard-Chabert, Brigitte, Hillaire, Sophie, Di Martino, Vincent, Bonnet, Delphine, Payssan-Sicart, Virginie, Pomes, Chloe, Bailly, François, Beaudoin, Marjolaine, Giboz, Dominique, Hartig-Lavie, Kerstin, Maynard, Marianne, Billaud, Eric, Boutoille, David, Cavellec, Morane, Cheraud-Carpentier, Marjorie, Hubert, Isabelle, Benhida, Jaouad, Lannes, Adrien, Lunel, Françoise, Oberti, Frédéric, Boyer, Nathalie, Giuily, Nathalie, Castelnau, Corinne, Scoazec, Giovanna, Chibah, Aziza, Keser, Sylvie, Bonardi, Karim, Vallet-Pichard, Anaïs, Sogni, Philippe, Foucher, Juliette, Hiriart, Jean-Baptiste, Wilson, Amy, Shili, Sarah, Chermak, Faiza, Ansaldi, Christelle, Ben Amara, Nisserine, Chouquet, Laëtitia, De Luca, Emilie, Oules, Valérie, Anty, Rodolphe, Gelsi, Eve, Truchi, Régine, Luckina, Elena, Messaoudi, Nadia, Moussali, Joseph, De Dieuleveult, Barbara, Labarriere, Damien, Poter, Pascal, Si Ahmed, Si Nafa, Grando-Lemaire, Véronique, Bourcier, Valérie, Brulé, Séverine, Stalhberger, Thomas, Jezequel, Caroline, Brener, Audrey, Laligant, Anne, Rabot, Aline, Renard, Isabelle, Baumert, Thomas F., Dofföel, Michel, Mutter, Catherine, Simo-Noumbissie, Pauline, Razi, Esma, Barraud, Hélène, Bensenane, Mouni, Nani, Abdelbasset, Hassani-Nani, Sarah, Bernard, Marie-Albertine, Bismuth, Michael, Caillo, Ludovic, Faure, Stéphanie, Ripault, Marie Pierre, Bureau, Christophe, Peron, Jean Marie, Robic, Marie Angèle, Tarallo, Léa, Faure, Marine, Froissart, Bruno, Hilleret, Marie-Noelle, Zarski, Jean-Pierre, Goria, Odile, Grard, Victorien, Montialoux, Hélène, François, Muriel, Ouedraogo, Christian, Pauleau, Christelle, Varault, Anne, Andreani, Tony, Angoulevant, Bénédicte, Chevance, Azeline, Serfaty, Lawrence, Antonini, Teresa, Coilly, Audrey, Duclos Vallée, Jean-Charles, Tateo, Mariagrazia, Bonny, Corinne, Brigitte, Chanteranne, Lamblin, Géraldine, Muti, Léon, Babouri, Abdenour, Filipe, Virginie, Barrault, Camille, Costes, Laurent, Hagège, Hervé, Merbah, Soraya, Carrier, Paul, Debette-Gratien, Maryline, Jacques, Jérémie, Lassailly, Guillaume, Artu, Florent, Canva, Valérie, Dharancy, Sébastien, Louvet, Alexandre, Latournerie, Marianne, Bardou, Marc, Mouillot, Thomas, Bacq, Yannick, Barbereau, Didier, Nicolas, Charlotte, Chevalier, Caroline, Archambeaud, Isabelle, Habes, Sarah, Botta-Fridlund, Danièle, Saillard, Eric, Lafrance, Marie-Josée, Cacoub, Patrice, Carrat, Fabrice, Carrieri, Patrizia, Delarocque-Astagneau, Elisabeth, De Ledinghen, Victor, Dorival, Céline, Dubuisson, Jean, Housset, Chantal, Larrey, Dominique, Marcellin, Patrick, Pawlotsky, Jean-Michel, Petrov-Sanchez, Ventzislava, Vaux, Sophie, Wittkop, Linda, Yazdanpanah, Yazdan, Zucman-Rossi, Jessica, Ganne-Carrié, Nathalie, Chaffaut, Cendrine, Moreno, Christophe, Moirand, Romain, Carbonell, Nicolas, Duclos-Vallée, Jean-Charles, de Ledinghen, Victor, Ozenne, Violaine, Henrion, Jean, Perlemuter, Gabriel, Amiot, Xavier, Chevret, Sylvie, Najean, Marie, Layese, Richard, Zarca, Kevin, Segar, Laeticia Blampain, Cagnot, Carole, N’Kontchou, Gisèle, Ronot, Maxime, Audureau, Etienne, and Durand-Zaleski, Isabelle
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- 2022
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8. Impact of cirrhosis aetiology on incidence and prognosis of hepatocellular carcinoma diagnosed during surveillance
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Ganne-Carrié, Nathalie, Chaffaut, Cendrine, Archambeaud, Isabelle, d’Alteroche, Louis, Oberti, Frédéric, Roulot, Dominique, Moreno, Christophe, Louvet, Alexandre, Dao, Thông, Moirand, Romain, Goria, Odile, Nguyen-Khac, Eric, Carbonell, Nicolas, Duclos-Vallée, Jean-Charles, Pol, Stanislas, de Ledinghen, Victor, Ozenne, Violaine, Henrion, Jean, Péron, Jean-Marie, Tran, Albert, Perlemuter, Gabriel, Amiot, Xavier, Zarski, Jean-Pierre, Chevret, Sylvie, Nahon, Pierre, Asselah, Tarik, Guyader, Dominique, Fontaine, Hélène, Pageaux, Georges-Philippe, De Lédinghen, Victor, Ouzan, Denis, Zoulim, Fabien, Bronowicki, Jean-Pierre, Decaens, Thomas, Riachi, Ghassan, Calès, Paul, Alric, Laurent, Bourlière, Marc, Mathurin, Philippe, Dharancy, Sebastien, Blanc, Jean-Frédéric, Abergel, Armand, Chazouillères, Olivier, Mallat, Ariane, Grangé, Jean-Didier, Attali, Pierre, Wartelle, Claire, Thabut, Dominique, Pilette, Christophe, Silvain, Christine, Christidis, Christos, Bernard-Chabert, Brigitte, Hillaire, Sophie, Di Martino, Vincent, N’Kontchou, Gisèle, Layese, Richard, and Audureau, Etienne
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- 2021
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9. Including Ratio of Platelets to Liver Stiffness Improves Accuracy of Screening for Esophageal Varices That Require Treatment
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Huvelin, Sylvie Sacher, Calès, Paul, Valla, Dominique, Bureau, Christophe, Olivier, Anne, Oberti, Frédéric, Boursier, Jérôme, Galmiche, Jean Paul, Vinel, Jean Pierre, Duburque, Clotilde, Attar, Alain, Archambeaud, Isabelle, Benamouzig, Robert, Gaudric, Marianne, Luet, Dominique, Couzigou, Patrice, Planche, Lucie, Coron, Emmanuel, Hiriart, Jean-Baptiste, Chermak, Faiza, Charbonnier, Maude, Nahon, Pierre, Marcellin, Patrick, Guyader, Dominique, Pol, Stanislas, Fontaine, Hélène, Larrey, Dominique, De Lédinghen, Victor, Ouzan, Denis, Zoulim, Fabien, Roulot, Dominique, Tran, Albert, Bronowicki, Jean-Pierre, Zarski, Jean-Pierre, Leroy, Vincent, Riachi, Ghassan, Péron, Jean-Marie, Alric, Laurent, Bourlière, Marc, Mathurin, Philippe, Dharancy, Sebastien, Blanc, Jean-Frédéric, Abergel, Armand, Serfaty, Lawrence, Mallat, Ariane, Grangé, Jean-Didier, Attali, Pierre, Bacq, Yannick, Wartelle, Claire, Dao, Thông, Benhamou, Yves, Pilette, Christophe, Silvain, Christine, Christidis, Christos, Capron, Dominique, Thiefin, Gérard, Hillaire, Sophie, Di Martino, Vincent, Berger, Arthur, Ravaioli, Federico, Farcau, Oana, Festi, Davide, Stefanescu, Horia, Buisson, François, Ganne-Carriè, Nathalie, Berzigotti, Annalisa, de Ledinghen, Victor, and Petta, Salvatore
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- 2021
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10. Pravastatin combination with sorafenib does not improve survival in advanced hepatocellular carcinoma
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Jouve, Jean-Louis, Lecomte, Thierry, Bouché, Olivier, Barbier, Emilie, Khemissa Akouz, Faiza, Riachi, Ghassan, Nguyen Khac, Eric, Ollivier-Hourmand, Isabelle, Debette-Gratien, Maryline, Faroux, Roger, Villing, Anne-Laure, Vergniol, Julien, Ramee, Jean-François, Bronowicki, Jean-Pierre, Seitz, Jean-François, Legoux, Jean-Louis, Denis, Jacques, Manfredi, Sylvain, and Phelip, Jean-Marc
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- 2019
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11. Validation of Baveno VI Criteria for Screening and Surveillance of Esophageal Varices in Patients With Compensated Cirrhosis and a Sustained Response to Antiviral Therapy
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Nahon, Pierre, Marcellin, Patrick, Guyader, Dominique, Pol, Stanislas, Fontaine, Hélène, Larrey, Dominique, De Lédinghen, Victor, Ouzan, Denis, Zoulim, Fabien, Roulot, Dominique, Tran, Albert, Bronowicki, Jean-Pierre, Zarski, Jean-Pierre, Leroy, Vincent, Riachi, Ghassan, Calès, Paul, Péron, Jean-Marie, Alric, Laurent, Bourlière, Marc, Mathurin, Philippe, Dharancy, Sebastien, Blanc, Jean-Frédéric, Abergel, Armand, Serfaty, Lawrence, Mallat, Ariane, Grangé, Jean-Didier, Attali, Pierre, Bacq, Yannick, Wartelle, Claire, Dao, Thông, Thabut, Dominique, Pilette, Christophe, Silvain, Christine, Christidis, Christos, Capron, Dominique, Thiefin, Gérard, Hillaire, Sophie, Di Martino, Vincent, Bureau, Christophe, Layese, Richard, Bourcier, Valérie, Hammouche, Maryam, Cagnot, Carole, Goria, Odile, Wartelle-Bladou, Claire, Bernard-Chabert, Brigitte, Sutton, Angela, Audureau, Etienne, and Roudot-Thoraval, Françoise
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- 2019
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12. Incidence of Hepatocellular Carcinoma After Direct Antiviral Therapy for HCV in Patients With Cirrhosis Included in Surveillance Programs
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Nahon, Pierre, Marcellin, Patrick, Guyader, Dominique, Pol, Stanislas, Fontaine, Hélène, Larrey, Dominique, De Lédinghen, Victor, Ouzan, Denis, Zoulim, Fabien, Roulot, Dominique, Tran, Albert, Bronowicki, Jean-Pierre, Zarski, Jean-Pierre, Leroy, Vincent, Riachi, Ghassan, Calès, Paul, Péron, Jean-Marie, Alric, Laurent, Bourlière, Marc, Mathurin, Philippe, Dharancy, Sebastien, Blanc, Jean-Frédéric, Abergel, Armand, Serfaty, Lawrence, Mallat, Ariane, Grangé, Jean-Didier, Attali, Pierre, Bacq, Yannick, Wartelle, Claire, Dao, Thông, Thabut, Dominique, Pilette, Christophe, Silvain, Christine, Christidis, Christos, Nguyen-Khac, Eric, Bernard-Chabert, Brigitte, Hillaire, Sophie, Di Martino, Vincent, Layese, Richard, Bourcier, Valérie, Cagnot, Carole, Zucman, David, Sutton, Angela, Roudot-Thoraval, Françoise, and Audureau, Etienne
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- 2018
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13. Compliance With Hepatocellular Carcinoma Surveillance Guidelines Associated With Increased Lead-Time Adjusted Survival of Patients With Compensated Viral Cirrhosis: A Multi-Center Cohort Study
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Nahon, Pierre, Marcellin, Patrick, Guyader, Dominique, Pol, Stanislas, Fontaine, Hélène, Larrey, Dominique, De Lédinghen, Victor, Ouzan, Denis, Zoulim, Fabien, Roulot, Dominique, Tran, Albert, Bronowicki, Jean-Pierre, Zarski, Jean-Pierre, Leroy, Vincent, Riachi, Ghassan, Calès, Paul, Péron, Jean-Marie, Alric, Laurent, Bourlière, Marc, Mathurin, Philippe, Dharancy, Sebastien, Blanc, Jean-Frédéric, Abergel, Armand, Serfaty, Lawrence, Mallat, Ariane, Grangé, Jean-Didier, Attali, Pierre, Bacq, Yannick, Wartelle, Claire, Dao, Thông, Thabut, Dominique, Pilette, Christophe, Silvain, Christine, Christidis, Christos, Capron, Dominique, Thiefin, Gérard, Hillaire, Sophie, Di Martino, Vincent, Costentin, Charlotte E., Layese, Richard, Bourcier, Valérie, Cagnot, Carole, Nguyen-khac, Eric, Bernard-Chabert, Brigitte, Zucman, David, Sutton, Angela, Letouzé, Eric, Imbeaud, Sandrine, Zucman-Rossi, Jessica, Audureau, Etienne, and Roudot-Thoraval, Françoise
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- 2018
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14. Classification of PRSS1 variants responsible for chronic pancreatitis: An expert perspective from the Franco-Chinese GREPAN Study Group
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Masson, Emmanuelle, primary, Zou, Wen-Bin, additional, Pu, Na, additional, Rebours, Vinciane, additional, Génin, Emmanuelle, additional, Wu, Hao, additional, Lin, Jin-Huan, additional, Wang, Yuan-Chen, additional, Li, Zhao-Shen, additional, Cooper, David N., additional, Férec, Claude, additional, Liao, Zhuan, additional, Chen, Jian-Min, additional, Abrantes, Amandine, additional, Aguilera Munoz, Lina, additional, Albouys, Jérémie, additional, Alric, Laurent, additional, Amiot, Xavier, additional, Archambeaud, Isabelle, additional, Audiau, Solène, additional, Bastide, Laetitia, additional, Baudon, Julien, additional, Bellaiche, Guy, additional, Bellon, Serge, additional, Bertrand, Valérie, additional, Bideau, Karine, additional, Billiemaz, Kareen, additional, Billioud, Claire, additional, Bonnefoy, Sabine, additional, Borderon, Corinne, additional, Bournet, Barbara, additional, Breton, Estelle, additional, Brugel, Mathias, additional, Buscail, Louis, additional, Cadiot, Guillaume, additional, Camus, Marine, additional, Causse, Xavier, additional, Chamouard, Patrick, additional, Chaput, Ulriikka, additional, Cholet, Franck, additional, Ciocan, Dragos Marius, additional, Clavel, Christine, additional, Coffin, Benoit, additional, Coimet-Berger, Laura, additional, Creveaux, Isabelle, additional, Culetto, Adrian, additional, Daboussi, Oussama, additional, De Mestier, Louis, additional, Degand, Thibault, additional, D'Engremont, Christelle, additional, Denis, Bernard, additional, Dermine, Solène, additional, Desgrippes, Romain, additional, Drouet D'Aubigny, Augustin, additional, Enaud, Raphaël, additional, Fabre, Alexandre, additional, Gargot, Dany, additional, Gelsi, Eve, additional, Gentilcore, Elena, additional, Gincul, Rodica, additional, Ginglinger-Favre, Emmanuelle, additional, Giovannini, Marc, additional, Gomercic, Cécile, additional, Gondran, Hannah, additional, Grainville, Thomas, additional, Grandval, Philippe, additional, Grasset, Denis, additional, Grimaldi, Stéphane, additional, Grimbert, Sylvie, additional, Hagege, Hervé, additional, Heissat, Sophie, additional, Hentic, Olivia, additional, Herber-Mayne, Anne, additional, Hervouet, Marc, additional, Hoibian, Solene, additional, Jacques, Jérémie, additional, Jais, Bénédicte, additional, Kaassis, Mehdi, additional, Koch, Stéphane, additional, Lacaze, Elodie, additional, Lacroute, Joël, additional, Lamireau, Thierry, additional, Laurent, Lucie, additional, Le Guillou, Xavier, additional, Le Rhun, Marc, additional, Leblanc, Sarah, additional, Levy, Philippe, additional, Lievre, Astrid, additional, Lorenzo, Diane, additional, Maire, Frédérique, additional, Marcel, Kévin, additional, Matias, Clément, additional, Mauillon, Jacques, additional, Morgant, Stéphanie, additional, Moussata, Driffa, additional, Muller, Nelly, additional, Nambot, Sophie, additional, Napoleon, Bertrand, additional, Olivier, Anne, additional, Pagenault, Maël, additional, Pelletier, Anne-laure, additional, Pennec, Olivier, additional, Pinard, Fabien, additional, Pioche, Mathieu, additional, Prost, Bénédicte, additional, Queneherve, Lucille, additional, Reboux, Noemi, additional, Rekik, Samia, additional, Riachi, Ghassan, additional, Rohmer, Barbara, additional, Roquelaure, Bertrand, additional, Rosa Hezode, Isabelle, additional, Rostain, Florian, additional, Saurin, Jean-Christophe, additional, Servais, Laure, additional, Stan-Iuga, Roxana, additional, Subtil, Clément, additional, Texier, Charles, additional, Thomassin, Lucie, additional, Tougeron, David, additional, Tsakiris, Laurent, additional, Valats, Jean-Christophe, additional, Vuitton, Lucine, additional, Wallenhorst, Timothée, additional, Wangerme, Marc, additional, Zanaldi, Hélène, additional, Zerbib, Frank, additional, Bai, Chen-Guang, additional, Bian, Yun, additional, Cai, Zhen-Zhai, additional, Chang, Xiao-Yan, additional, Chen, Guo-Dong, additional, Cheng, Li, additional, Chen, Yu, additional, Guo, Jin-Tao, additional, Guo, Tao, additional, Han, Jun-Ling, additional, He, Chao-Hui, additional, Hu, Liang-Hao, additional, Huang, Hao-Jie, additional, Huang, Li, additional, Huang, Li-Ya, additional, Huang, Si-Lin, additional, Huang, Wei, additional, Jiang, Fei, additional, Jiang, Hui, additional, Lu, Feng-Chun, additional, Lu, Guo-Tao, additional, Lu, Zi-Peng, additional, Li, Hui-Ping, additional, Li, Jing, additional, Li, Le, additional, Li, Qiang, additional, Li, Xiao-Yu, additional, Lin, Qing, additional, Lin, Yu-Li, additional, Liu, Gai-Fang, additional, Liu, Jie-Min, additional, Liu, Li-Xin, additional, Liu, Pi, additional, Liu, Yi-Pin, additional, Lu, Dong, additional, Shao, Xiao-Dong, additional, Shao, Zhuo, additional, Song, Xu-Rui, additional, Wang, Lei, additional, Wang, Li-Juan, additional, Wang, Li-Sheng, additional, Wang, Lin, additional, Wang, Wei, additional, Wang, Zheng, additional, Wen, Li, additional, Wu, Xi, additional, Xin, Lei, additional, Xue, Jing, additional, Yang, Hong, additional, Yang, Jian-Feng, additional, Yin, Tao, additional, Zhang, Bei-Ping, additional, Zhang, Guo-Wei, additional, Zhang, Hong, additional, Zhang, Rong-Chun, additional, Zhao, Yi-Jun, additional, Zhou, Si-Si, additional, and Zhu, Ke-Xiang, additional
- Published
- 2023
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15. Epidemiology and characteristics of hepatocellular carcinoma in France: results of the first 2000 patients in real-life situations from the French prospective chief cohort
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Khac, Eric Nguyen, primary, Merle, Philippe, additional, Hajer, Ben Khadhra, additional, Amaddeo, Giuliana, additional, Decaens, Thomas, additional, Uguen, Thomas, additional, Blanc, Jean-Frédéric, additional, Ganne-Carrié, Nathalie, additional, Bouattour, Mohamed, additional, Cattan, Stéphane, additional, Silvain, Christine, additional, Riachi, Ghassan, additional, Peron, Jean Marie, additional, Anty, Rodolphe, additional, Bronowicki, Jean-Pierre, additional, Baron, Aurore, additional, Pageaux, Georges-Philippe, additional, Loustaud-Ratti, Veronique, additional, Oberti, Frédéric, additional, Allaire, Manon, additional, Manfredi, Sylvain, additional, Merabet, Yasmina Ben, additional, Ollivier-Hourmand, Isabelle, additional, Lequoy, Marie, additional, Nousbaum, Jean Baptiste, additional, Gelu-Simeon, Moana, additional, Grados, Lucien, additional, Nahon, Pierre, additional, Costentin, Charlotte, additional, Ducournau, Gerard, additional, and Ganry, Olivier, additional
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- 2023
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16. Effect on HBs antigen clearance of addition of pegylated interferon alfa-2a to nucleos(t)ide analogue therapy versus nucleos(t)ide analogue therapy alone in patients with HBe antigen-negative chronic hepatitis B and sustained undetectable plasma hepatitis B virus DNA: a randomised, controlled, open-label trial
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Bourlière, Marc, Rabiega, Pascaline, Ganne-Carrie, Nathalie, Serfaty, Lawrence, Marcellin, Patrick, Barthe, Yoann, Thabut, Dominique, Guyader, Dominique, Hezode, Christophe, Picon, Magali, Causse, Xavier, Leroy, Vincent, Bronowicki, Jean Pierre, Carrieri, Patrizia, Riachi, Ghassan, Rosa, Isabelle, Attali, Pierre, Molina, Jean Michel, Bacq, Yannick, Tran, Albert, Grangé, Jean Didier, Zoulim, Fabien, Fontaine, Hélène, Alric, Laurent, Bertucci, Inga, Bouvier-Alias, Magali, and Carrat, Fabrice
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- 2017
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17. Safety and efficacy of the combination simeprevir-sofosbuvir in HCV genotype 1- and 4-mono-infected patients from the French ANRS CO22 hepather cohort
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Laurain, Anne, Metivier, Sophie, Haour, Georges, Larrey, Dominique, Dorival, Céline, Hezode, Christophe, Zoulim, Fabien, Marcellin, Patrick, Bourliere, Marc, Zarski, Jean-Pierre, Thabut, Dominique, Alric, Laurent, Ganne-Carrie, Nathalie, Cales, Paul, Bronowicki, Jean-Pierre, Riachi, Ghassan, Geist, Claire, Causse, Xavier, Abergel, Armand, Chazouilleres, Olivier, Mathurin, Philippe, Guyader, Dominique, Samuel, Didier, Tran, Albert, Loustaud-Ratti, Véronique, Petrov-Sanchez, Ventzislava, Diallo, Alpha, Luzivika-Nzinga, Clovis, Fontaine, Hélène, Carrat, Fabrice, Pol, Stanislas, and on behalf of the ANRS/AFEF HEPATHER study group
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- 2019
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18. ABO blood group does not influence Child‐Pugh A cirrhosis outcome: An observational study from CIRRAL and ANRS CO12 CIRVIR cohorts
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Ollivier-Hourmand, Isabelle, Repesse, yohann, Nahon, Pierre, Chaffaut, Cendrine, Dao, Thông, Nguyen, Thi Thu Nga, Marcellin, Patrick, Roulot, Dominique, de Ledinghen, Victor, Pol, Stanislas, Guyader, Dominique, Archambeaud, Isabelle, Zoulim, Fabien, Oberti, Frédéric, Tran, Albert, Bronowicki, Jean-Pierre, d'Alteroche, Louis, Ouzan, Denis, Peron, Jean-Marie, Zarski, Jean-Pierre, Bourliere, Marc, Larrey, Dominique, Louvet, Alexandre, Cales, Paul, Abergel, Armand, Mathurin, Philippe, Mallat, Ariane, Blanc, Jean-Frederic, Nguyen-Khac, Eric, Riachi, Ghassan, Alric, Laurent, Serfaty, Lawrence, Antonini, Teresa, Moreno, Christophe, Attali, Pierre, Thabut, Dominique, Pilette, Christophe, Grange, Jean-Didier, Silvain, Christine, Carbonell, Nicolas, Bernard-Chabert, Brigitte, Goria, Odile, Wartelle, Claire, Moirand, Romain, Christidis, Christos, Perlemuter, Gabriel, Ozenne, Violaine, Henrion, Jean, Hillaire, Sophie, Di Martino, Vincent, Amiot, Xavier, Sutton, Angela, Barget, Nathalie, Chevret, Sylvie, Ganne‐carrie, Nathalie, CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN), Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPC), Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité (CRESS (U1153 / UMR_A_1125 / UMR_S_1153)), Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université (HESAM)-HESAM Université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPC)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Hôpital Avicenne [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Institut Cochin (IC UM3 (UMR 8104 / U1016)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPC), Nutrition, Métabolismes et Cancer (NuMeCan), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), CHU Pontchaillou [Rennes], Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM), Centre méditerranéen de médecine moléculaire (C3M), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UCA), Institut Arnault Tzanck, Service de Gastro-entérologie - Hépatologie [Purpan], CHU Toulouse [Toulouse], CHU Grenoble, Groupe de Recherche sur l'alcool et les pharmacodépendances - UMR INSERM_S 1247 (GRAP), Université de Picardie Jules Verne (UPJV)-Institut National de la Santé et de la Recherche Médicale (INSERM), Nutrition, inflammation et dysfonctionnement de l'axe intestin-cerveau (ADEN), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institute for Research and Innovation in Biomedicine (IRIB), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Service d'Hépato-Gastroentérologie [CHU Rouen], Hôpital Charles Nicolle [Rouen]-CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), UNIROUEN - UFR Santé (UNIROUEN UFR Santé), Normandie Université (NU)-Normandie Université (NU), Immunologie et virologie des cancers. Immunologie des interactions cellulaires et moléculaires (Inserm U152), Institut National de la Santé et de la Recherche Médicale (INSERM), Equipe 2 : ECSTRA - Epidémiologie Clinique, STatistique, pour la Recherche en Santé (CRESS - U1153), HESAM Université (HESAM)-HESAM Université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPC)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), This work was supported by a research grant from the French National Society of Gastroenterology (SNFGE), a research grant from the French Agency for Research on AIDS and Viral Hepatitis (ANRS), and a research grant from Abbvie., École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Centre de Recherche en Cancérologie de Lyon (UNICANCER/CRCL), Centre Léon Bérard [Lyon]-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Pôle Maladies de l'appareil digestif [CHU Toulouse], Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Hôpital Charles Nicolle [Rouen], CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-CHU Rouen, and HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Conservatoire National des Arts et Métiers [CNAM] (CNAM)
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Liver Cirrhosis ,Hepatology ,[SDV]Life Sciences [q-bio] ,alcoholic cirrhosis ,ABO blood group ,non-malignant portal vein thrombosis ,ABO Blood-Group System ,Hypertension, Portal ,Disease Progression ,outcome ,Humans ,Prospective Studies ,viral cirrhosis ,Child-Pugh A cirrhosis - Abstract
International audience; Background and aims: Non-O blood group promotes deep vein thrombosis and liver fibrosis in both general population and hepatitis C. We aimed to evaluate the influence of Non-O group on the outcome of Child-Pugh A cirrhotic patients.Methods: We used two prospective cohorts of Child-Pugh A cirrhosis due to either alcohol or viral hepatitis. Primary end point was the cumulated incidence of 'Decompensation' at 3 years, defined as the occurrence of ascites , hydrothorax, encephalopathy, gastrointestinal bleeding related to portal hypertension, or bilirubin >45 μmol/L. Secondary end points were the cumulated incidences of (1) 'Disease Progression' including a « decompensation» or « the occurrence of one or more parameters » among: prothrombin time (PT)
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- 2022
19. Identification of protease-sensitive but not misfolding PNLIP variants in familial and hereditary pancreatitis
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Abrantes, Amandine, Aguilera Munoz, Lina, Albouys, Jérémie, Alric, Laurent, Amiot, Xavier, Archambeaud, Isabelle, Audiau, Solène, Bastide, Laetitia, Baudon, Julien, Bellaiche, Guy, Bellon, Serge, Bertrand, Valérie, Bideau, Karine, Billiemaz, Kareen, Billioud, Claire, Bonnefoy, Sabine, Borderon, Corinne, Bournet, Barbara, Breton, Estelle, Brugel, Mathias, Buscail, Louis, Cadiot, Guillaume, Camus, Marine, Causse, Xavier, Chamouard, Patrick, Chaput, Ulriikka, Cholet, Franck, Ciocan, Dragos Marius, Clavel, Christine, Coffin, Benoit, Coimet-Berger, Laura, Creveaux, Isabelle, Culetto, Adrian, Daboussi, Oussama, Dalstein, Véronique, De Mestier, Louis, Degand, Thibault, d'Engremont, Christelle, Denis, Bernard, Dermine, Solène, Desgrippes, Romain, Drouet d'Aubigny, Augustin, Enaud, Raphaël, Fabre, Alexandre, Gargot, Dany, Gelsi, Eve, Gentilcore, Elena, Gincul, Rodica, Ginglinger-Favre, Emmanuelle, Giovannini, Marc, Gomercic, Cécile, Gondran, Hannah, Grainville, Thomas, Grandval, Philippe, Grasset, Denis, Grimaldi, Stéphane, Grimbert, Sylvie, Hagege, Hervé, Heissat, Sophie, Hentic, Olivia, Herber-Mayne, Anne, Hervouet, Marc, Hoibian, Solene, Jacques, Jérémie, Jais, Bénédicte, Kaassis, Mehdi, Koch, Stéphane, Lacaze, Elodie, Lacroute, Joël, Lamireau, Thierry, Laurent, Lucie, Le Guillou, Xavier, Leblanc, Sarah, Levy, Philippe, Lievre, Astrid, Lorenzo, Diane, Maire, Frédérique, Marcel, Kévin, Matias, Clément, Mauillon, Jacques, Morgant, Stéphanie, Moussata, Driffa, Muller, Nelly, Nambot, Sophie, Napoleon, Bertrand, Olivier, Anne, Pagenault, Maël, Pelletier, Anne-laure, Pennec, Olivier, Pinard, Fabien, Pioche, Mathieu, Prost, Bénédicte, Queneherve, Lucille, Rebours, Vinciane, Reboux, Noemi, Rekik, Samia, Riachi, Ghassan, Rohmer, Barbara, Roquelaure, Bertrand, Rosa Hezode, Isabelle, Rostain, Florian, Saurin, Jean-Christophe, Servais, Laure, Stan-Iuga, Roxana, Subtil, Clément, Texier, Charles, Thomassin, Lucie, Tougeron, David, Tsakiris, Laurent, Valats, Jean-Christophe, Vuitton, Lucine, Wallenhorst, Timothée, Wangerme, Marc, Zanaldi, Hélène, Zerbib, Frank, Masson, Emmanuelle, Berthet, Stéphanie, Le Gac, Gerald, Le Rhun, Marc, Ka, Chandran, Autret, Sandrine, Gourlaouen, Isabelle, Cooper, David N., Férec, Claude, and Chen, Jian-Min
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- 2023
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20. Cannabis use as a factor of lower corpulence in hepatitis C-infected patients: results from the ANRS CO22 Hepather cohort
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Barré, Tangui, Carrat, Fabrice, Ramier, Clémence, Fontaine, Hélène, Di Beo, Vincent, Bureau, Morgane, Dorival, Céline, Larrey, Dominique, Delarocque-Astagneau, Elisabeth, Mathurin, Philippe, Marcellin, Fabienne, Petrov-Sanchez, Ventzislava, Cagnot, Carole, Carrieri, Patrizia, Pol, Stanislas, Protopopescu, Camelia, Alric, Laurent, Pomes, Chloe, Zoulim, Fabien, Maynard, Marianne, Bai, Roxane, Hucault, Lucie, Bailly, François, Raffi, François, Billaud, Eric, Boutoille, David, Lefebvre, Maeva, André-Garnier, Elisabeth, Cales, Paul, Hubert, Isabelle, Lannes, Adrien, Lunel, Françoise, Boursier, Jérôme, Asselah, Tarik, Boyer, Nathalie, Giuily, Nathalie, Castelnau, Corinne, Scoazec, Giovanna, Rousseaud, Emilie, Vallet-Pichard, Anaïs, Sogni, Philippe, de Ledinghen, Victor, Foucher, Juliette, Hiriart, Jean-Baptiste, M’bouyou, Jancell, Irlès-Depé, Marie, Bourlière, Marc, Ahmed, Si Nafa Si, Oules, Valérie, Tran, Albert, Anty, Rodolphe, Gelsi, Eve, Truchi, Régine, Thabut, Dominique, Hammeche, Saloua, Moussali, Joseph, Causse, Xavier, de Dieuleveult, Barbara, Ouarani, Brahim, Labarrière, Damien, Ganne, Nathalie, Grando-Lemaire, Véronique, Nahon, Pierre, Brulé, Séverine, Ulker, Betul, Guyader, Dominique, Jezequel, Caroline, Brener, Audrey, Laligant, Anne, Rabot, Aline, Renard, Isabelle, Habersetzer, François, Baumert, Thomas, Doffoel, Michel, Mutter, Catherine, Simo-Noumbissie, Pauline, Razi, Esma, Bronowicki, Jean-Pierre, Barraud, Hélène, Bensenane, Mouni, Nani, Abdelbasset, Hassani-Nani, Sarah, Bernard, Marie-Albertine, Pageaux, Georges-Philippe, Meszaros, Magda, Metivier, Sophie, Bureau, Christophe, Morales, Thibault, Peron, Jean Marie, Robic, Marie Angèle, Decaens, Thomas, Faure, Marine, Froissart, Bruno, Hilleret, Marie-Noelle, Zarski, Jean-Pierre, Riachi, Ghassan, Goria, Odile, Paris, Fatima, Montialoux, Hélène, Leroy, Vincent, Amaddeo, Giuliana, Varaut, Anne, Simoes, Mélanie, Amzal, Rachida, Chazouillières, Olivier, Andreani, Tony, Angoulevant, Bénédicte, Chevance, Azeline, Serfaty, Lawrence, Samuel, Didier, Antonini, Teresa, Coilly, Audrey, Duclos-Vallée, Jean-Charles, Tateo, Mariagrazia, Abergel, Armand, Reymond, Maud, Brigitte, Chanteranne, Benjamin, Buchard, Muti, Léon, Geist, Claire, Conroy, Guillaume, Riffault, Raphaëlle, Rosa, Isabelle, Barrault, Camille, Costes, Laurent, Hagège, Hervé, Loustaud-Ratti, Véronique, Carrier, Paul, Debette-Gratien, Maryline, Lassailly, Guillaume, Lemaitre, Elise, Canva, Valérie, Dharancy, Sébastien, Louvet, Alexandre, Minello, Anne, Latournerie, Marianne, Bardou, Marc, Mouillot, Thomas, D’alteroche, Louis, Barbereau, Didier, Nicolas, Charlotte, Elkrief, Laure, Jaillais, Anaïs, Gournay, Jérôme, Chevalier, Caroline, Archambeaud, Isabelle, Habes, Sarah, Portal, Isabelle, Gelu-Simeon, Moana, Saillard, Eric, Lafrance, Marie-Josée, Catherine, Lucie, Chau, Frederic, Goderel, Isabelle, Lusivika-Nzinga, Clovis, Bellance, Marc-Antoine, Bellet, Jonathan, Monfalet, Priscilla, Chane-Teng, Jessica, Bijaoui, Sephora, Pannetier, Grégory, Téoulé, François, Nicol, Jérôme, Sebal, Florian, Bekhti, Rafika, Boston, Anaïs, Nailler, Laura, Le Meut, Guillaume, Diallo, Alpha, Fourati, Slim, Housset, Chantal, Bruyand, Mathias, Wittkop, Linda, Zucman-Rossi, Jessica, L’hennaff, Marianne, Sizorn, Michèle, Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale (SESSTIM - U1252 INSERM - Aix Marseille Univ - UMR 259 IRD), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), CHU Saint-Antoine [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Département d'hépatologie [CHU Cochin], Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Cellules Souches, Plasticité Cellulaire, Médecine Régénératrice et Immunothérapies (IRMB), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Hôpital Raymond Poincaré [Garches], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service des Maladies de l'Appareil Digestif et de la Nutrition [CHRU Lille], Hôpital Claude Huriez [Lille], CHU Lille-CHU Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), and Agence Nationale de Recherches sur le Sida et les Hépatites Virales (ANRS)
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Endocannabinoid system ,Behaviors ,Δ9-Tetrahydrocannabinol ,[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie ,Obesity ,Sciences du Vivant [q-bio]/Médecine humaine et pathologie ,Chronic ,Body weight ,Hepatitis C ,Fibrosis ,Corpulence ,Cannabis ,Marijuana - Abstract
Background Patients with chronic hepatitis C virus (HCV) infection are at greater risk of developing metabolic disorders. Obesity is a major risk factor for these disorders, and therefore, managing body weight is crucial. Cannabis use, which is common in these patients, has been associated with lower corpulence in various populations. However, this relationship has not yet been studied in persons with chronic HCV infection. Methods Using baseline data from the French ANRS CO22 Hepather cohort, we used binary logistic and multinomial logistic regression models to test for an inverse relationship between cannabis use (former/current) and (i) central obesity (i.e., large waist circumference) and (ii) overweight and obesity (i.e., elevated body mass index (BMI)) in patients from the cohort who had chronic HCV infection. We also tested for relationships between cannabis use and both waist circumference and BMI as continuous variables, using linear regression models. Results Among the 6348 participants in the study population, 55% had central obesity, 13.7% had obesity according to their BMI, and 12.4% were current cannabis users. After multivariable adjustment, current cannabis use was associated with lower risk of central obesity (adjusted odds ratio, aOR [95% confidence interval, CI]: 0.45 [0.37–0.55]), BMI-based obesity (adjusted relative risk ratio (aRRR) [95% CI]: 0.27 [0.19–0.39]), and overweight (aRRR [95% CI]: 0.47 [0.38–0.59]). This was also true for former use, but to a lesser extent. Former and current cannabis use were inversely associated with waist circumference and BMI. Conclusions We found that former and, to a greater extent, current cannabis use were consistently associated with smaller waist circumference, lower BMI, and lower risks of overweight, obesity, and central obesity in patients with chronic HCV infection. Longitudinal studies are needed to confirm these relationships and to assess the effect of cannabis use on corpulence and liver outcomes after HCV cure. Trial registration ClinicalTrials.gov identifier: NCT01953458.
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- 2022
21. Liver Stiffness by Transient Elastography to Detect Porto‐Sinusoidal Vascular Liver Disease With Portal Hypertension
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Elkrief, Laure, Lazareth, Marie, Chevret, Sylvie, Paradis, Valérie, Magaz, Marta, Blaise, Lorraine, Rubbia‐Brandt, Laura, Moga, Lucile, Durand, François, Payancé, Audrey, Plessier, Aurélie, Chaffaut, Cendrine, Valla, Dominique, Malphettes, Marion, Diaz, Alba, Nault, Jean‐Charles, Nahon, Pierre, Audureau, Etienne, Ratziu, Vlad, Castera, Laurent, Garcia Pagan, Juan‐Carlos, Ganne‐Carrie, Nathalie, Rautou, Pierre‐Emmanuel, Marcellin, Patrick, Guyader, Dominique, Pol, Stanislas, Fontaine, Hélène, Larrey, Dominique, De Lédinghen, Victor, Ouzan, Denis, Zoulim, Fabien, Roulot, Dominique, Tran, Albert, Bronowicki, Jean‐Pierre, Zarski, Jean‐Pierre, Leroy, Vincent, Riachi, Ghassan, Calès, Paul, Péron, Jean‐Marie, Alric, Laurent, Bourlière, Marc, Mathurin, Philippe, Dharancy, Sebastien, Blanc, Jean‐Frédéric, Abergel Olivier Chazouillères, Armand, Mallat, Ariane, Grangé, Jean‐Didier, Attali, Pierre, Bacq, Yannick, Wartelle, Claire, Dao, Thông, Thabut, Dominique, Pilette, Christophe, Silvain, Christine, Christidis, Christos, Nguyen‐Khac, Eric, Bernard‐Chabert, Brigitte, Zucman, David, and Di Martino, Vincent
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0301 basic medicine ,medicine.medical_specialty ,Cirrhosis ,Hepatology ,business.industry ,Hepatitis C virus ,Fatty liver ,medicine.disease ,medicine.disease_cause ,Gastroenterology ,03 medical and health sciences ,Liver disease ,030104 developmental biology ,0302 clinical medicine ,Esophageal varices ,Internal medicine ,Ascites ,medicine ,Portal hypertension ,030211 gastroenterology & hepatology ,medicine.symptom ,Transient elastography ,business - Abstract
Background & aims Porto-sinusoidal vascular liver disease (PSVD) is a rare cause of portal hypertension. PSVD is still often misdiagnosed as cirrhosis, emphasizing the need to improve PSVD diagnosis strategies. Data on liver stiffness measurement (TE-LSM) using transient elastography, in PSVD are limited. The aim of this study was to evaluate the accuracy of TE-LSM to discriminate PSVD from cirrhosis in patients with signs of portal hypertension. Approach & results Retrospective multicenter study comparing TE-LSM in patients with PSVD, according to VALDIG criteria, to patients with compensated biopsy-proven cirrhosis related to alcohol (n=117), hepatitis C virus (HCV) infection (n=110) or non-alcoholic fatty liver disease (NAFLD) (n=46). All patients had at least one sign of portal hypertension among gastroesophageal varices, splenomegaly, porto-systemic collaterals, history of ascites or platelet count Conclusions This study including a total of 155 patients with PSVD and 273 patients with cirrhosis demonstrates that TE-LSM 20 kPa, PSVD is highly unlikely.
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- 2021
22. Effectiveness and Safety of Tenofovir Disoproxil Fumarate in Chronic Hepatitis B: A 3-Year, Prospective, Real-World Study in France
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Marcellin, Patrick, Zoulim, Fabien, Hézode, Christophe, Causse, Xavier, Roche, Bruno, Truchi, Régine, Pauwels, Arnaud, Ouzan, Denis, Dumortier, Jérôme, Pageaux, Georges-Philippe, Bourlière, Marc, Riachi, Ghassan, Zarski, Jean-Pierre, Cadranel, Jean-François, Tilliet, Valérie, Stern, Christiane, Pétour, Pascal, Libert, Olivier, Consoli, Silla M., and Larrey, Dominique
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- 2016
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23. Adjuvant I-131 Lipiodol After Resection or Radiofrequency Ablation for Hepatocellular Carcinoma
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Schwarz, Lilian, Bubenheim, Michael, Gardin, Isabelle, Huet, Emmanuel, Riachi, Ghassan, Clavier, Erick, Goria, Odile, Vera, Pierre, and Scotté, Michel
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- 2016
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24. Prediction of hepatocellular carcinoma in Hepatitis C patients with advanced fibrosis after sustained virologic response
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Azzi, Jessica, primary, Dorival, Céline, additional, Cagnot, Carole, additional, Fontaine, Hélène, additional, Lusivika-Nzinga, Clovis, additional, Leroy, Vincent, additional, De Ledinghen, Victor, additional, Tran, Albert, additional, Zoulim, Fabien, additional, Alric, Laurent, additional, Gournay, Jérôme, additional, Bronowicki, Jean-Pierre, additional, Decaens, Thomas, additional, Riachi, Ghassan, additional, Mikhail, Nabiel, additional, Soliman, Reham, additional, Shiha, Gamal, additional, Pol, Stanislas, additional, Carrat, Fabrice, additional, and Ganne-Carrié, Nathalie, additional
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- 2022
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25. Additional file 1 of Clinical outcomes after treatment with direct antiviral agents: beyond the virological response in patients with previous HCV-related decompensated cirrhosis
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Pageaux, Georges-Philippe, Nzinga, Clovis Lusivika, Ganne, Nathalie, Samuel, Didier, Dorival, C��line, Zoulim, Fabien, Cagnot, Carole, Decaens, Thomas, Thabut, Dominique, Asselah, Tarik, Mathurin, Philippe, Habersetzer, Fran��ois, Bronowicki, Jean-Pierre, Guyader, Dominique, Rosa, Isabelle, Leroy, Vincent, Chazouilleres, Olivier, de Ledinghen, Victor, Bourliere, Marc, Causse, Xavier, Cales, Paul, Metivier, Sophie, Loustaud-Ratti, V��ronique, Riachi, Ghassan, Alric, Laurent, Gelu-Simeon, Moana, Minello, Anne, Gournay, J��r��me, Geist, Claire, Tran, Albert, Abergel, Armand, Portal, Isabelle, d���Alteroche, Louis, Raffi, Fran��ois, Fontaine, H��l��ne, Carrat, Fabrice, and Pol, Stanislas
- Abstract
Additional file 1: Table S1. Balance of baseline covariates following IPTW analysis according to DAA exposure. Table S2. Summary of non-liver related deaths by cause. Table S3. Summary of liver related deaths by cause. Table S4. Factors associated with HCC, all-cause mortality, and liver transplant in all 559 patients included for study. Table S5. Characteristics of hepatocellular carcinoma according to DAA exposure. Table S6. Incidence rates of hepatocellular carcinoma, all-cause mortality, liver-related mortality, non-liver-related mortality, and liver transplant in all 559 patients under study according to DAA exposure period and virological response status. Table S7. Incidence rates of hepatocellular carcinoma, all-cause mortality, liver-related mortality, non-liver-related mortality, and liver transplant in all 55 patients with a Meld score>20 or Child-Pugh score C according to DAA exposure period and virological response status.
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- 2022
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26. EFFICACY AND SAFETY OF TREATMENT WITH BULEVIRTIDE IN CHRONIC HEPATITIS DELTA: PRELIMINARY RESULTS OF THE REAL LIFE ANRS HD EP01 BULEDELTA COHORT
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Zoulim, Fabien, Fougerou, Claire, Marullo Dominique, Roulot, Metivier, Sophie, de Ledinghen, Victor, Ratziu, Vlad, Mathurin, Philippe, Loustaud-Ratti, Veronique, Leroy, Vincent, Dumortier, Jerome, Jezequel, Caroline, Samuel, Didier, Carrie Nathalie, Ganne, Alric, Laurent, Franza Anne, Minello, Abergel, Armand, Pageaux, Georges-Philippe, Alfaiate, Dulce, Lascoux-Combe, Caroline, Lacombe, Karine, Rosa, Isabelle, Chazouilleres, Olivier, Riachi, Ghassan, Causse, Xavier, Chas, Julie, d'Alteroche, Louis, Bourliere, Marc, Carrieri Maria, Patrizia, Gordien, Emmanuel, Levrero, Massimo, Scholtes, Caroline, Serfaty, Lawrence, Sureau, Camille, Guedj, Jeremie, Renault, Alain, Birkle, Chloe, Le Pabic, Estelle, Tual, Christelle, Petrov-Sanchez, Ventzislava, Fontaine, Helene, Hospices Civils de Lyon (HCL), CHU Pontchaillou [Rennes], Centre d'Investigation Clinique [Rennes] (CIC), Université de Rennes (UR)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale (SESSTIM - U1252 INSERM - Aix Marseille Univ - UMR 259 IRD), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), and Jonchère, Laurent
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[SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology ,[SDV.MHEP.HEG] Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology - Abstract
Meeting Abstract 1017
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- 2022
27. An observational, prospective, multicenter study on the utilization and effectiveness of elbasvir–grazoprevir treatment association for chronic hepatitis C in France (ZEPHYR study).
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Bronowicki, Jean‐Pierre, Miailhes, Patrick, Hanslik, Bertrand, Ouzan, Denis, Larrey, Dominique, Riachi, Ghassan, Truchi, Régine, Jouannaud, Vincent, Pospait, Dan, Abergel, Armand, Causse, Xavier, Perot, Stéphanie, Skrzypski, Jérémy, De Hautecloque, Astrid, Spampinato, Axelle, Mariot, Philippe, and Sogni, Philippe
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CHRONIC hepatitis C ,ALCOHOLISM ,HEPATITIS C virus ,TREATMENT effectiveness ,FRENCH people - Abstract
Background and Aim: The efficacy and safety profiles of elbasvir–grazoprevir (EBR/GZR) has been established in more than 10 clinical trials. However, the characteristics of patients treated in routine clinical practice may differ. The present study was therefore designed to assess the real‐life effectiveness of EBR/GZR therapy in the general population and among subgroups with a high hepatitis C virus (HCV) prevalence in France. Methods: The Zephyr study was designed as a French, multicentre, prospective, observational study on EBR/GZR use and effectiveness in current practice in chronic hepatitis C patients. These results are based on data regarding the adult patients who received at least one dose of EBR/GZR between December 2017 and June 2019 in 67 French hospitals and clinics. Results: Overall, 478 patients were included. The Full Analysis Set corresponded to the 467 patients who met all the inclusion criteria and none of the exclusion criteria. Gender was balanced and the mean age was 55.7 ± 13.3 years. The patients were mainly treatment‐naive (89.5%) and infected with Genotype 1b (70.4%). Among the 75 patients with HCV Gt1a genotype, 56% had HCV RNA ≥ 800,000 IU/ml. F3–F4 fibrosis stage involved 24.2% of our population. Our subgroups were distributed among 110 migrants (23.6%), 58 (15.3%) using opioid agonist treatment, including people who inject drugs, 30 (6.8%) with chronic kidney disease Stages 3–5, 9 (1.9%) with an inherited blood disorder, and 4 (0.9%) coinfected with HIV. The remaining 269 (58.7%) were included in the general population subgroup. Overall, sustained virologic response 12 weeks after the end of treatment reached 98.0% and remained consistent among genotype, HCV RNA values, fibrosis stage, and the subgroup of interest. The rate of Alcohol Use Disorders Identification Test‐Consumption and Life Habit questionnaire completion was high at each visit, with data suggesting alcohol consumption decrease and an improvement in quality of life. Conclusions: Using real‐world evidence data on a French population representative of HCV patients, we confirmed the results obtained during EBR/GZR development program. [ABSTRACT FROM AUTHOR]
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- 2023
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28. Circulating DNA changes are predictive of disease progression after transarterial chemoembolization
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Sefrioui, David, primary, Verdier, Vincent, additional, Savoye‐Collet, Céline, additional, Beaussire, Ludivine, additional, Ghomadi, Slim, additional, Gangloff, Alice, additional, Goria, Odile, additional, Riachi, Ghassan, additional, Montialoux, Hélène, additional, Schwarz, Lilian, additional, Tuech, Jean‐Jacques, additional, Frebourg, Thierry, additional, Michel, Pierre, additional, Sarafan‐Vasseur, Nasrin, additional, and Di Fiore, Frédéric, additional
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- 2021
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29. Clinical Outcomes After Treatment With Direct Antiviral Agents: Beyond The Virological Response in Patients With Previous HCV-Related Decompensated Cirrhosis
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PAGEAUX, Georges-Philippe, primary, NZINGA, Clovis LUSIVIKA, additional, GANNE, Nathalie, additional, SAMUEL, Didier, additional, DORIVAL, Céline, additional, ZOULIM, Fabien, additional, CAGNOT, Carole, additional, DECAENS, Thomas, additional, THABUT, Dominique, additional, ASSELAH, Tarik, additional, MATHURIN, Philippe, additional, HABERSETZER, François, additional, BRONOWICKI, Jean-Pierre, additional, GUYADER, Dominique, additional, ROSA, Isabelle, additional, LEROY, Vincent, additional, CHAZOUILLERES, Olivier, additional, DE LEDINGHEN, Victor, additional, BOURLIERE, Marc, additional, CAUSSE, Xavier, additional, CALES, Paul, additional, METIVIER, Sophie, additional, LOUSTAUD-RATTI, Véronique, additional, RIACHI, Ghassan, additional, ALRIC, Laurent, additional, GELU-SIMEON, Moana, additional, MINELLO, Anne, additional, GOURNAY, Jérôme, additional, GEIST, Claire, additional, TRAN, Albert, additional, ABERGEL, Armand, additional, PORTAL, Isabelle, additional, D’ALTEROCHE, Louis, additional, RAFFI, François, additional, FONTAINE, Hélène, additional, CARRAT, Fabrice, additional, and POL, Stanislas, additional
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- 2021
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30. Predictive factors for hepatocellular carcinoma in chronic hepatitis B using structural equation modeling: a prospective cohort study
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Lam, Laurent, primary, Fontaine, Hélène, additional, Bourliere, Marc, additional, Lusivika-Nzinga, Clovis, additional, Dorival, Céline, additional, Thabut, Dominique, additional, Zoulim, Fabien, additional, Habersetzer, François, additional, Asselah, Tarik, additional, Duclos-Vallee, Jean-Charles, additional, Bronowicki, Jean-Pierre, additional, Mathurin, Philippe, additional, Decaens, Thomas, additional, Ganne, Nathalie, additional, Guyader, Dominique, additional, Leroy, Vincent, additional, Rosa, Isabelle, additional, De Ledinghen, Victor, additional, Cales, Paul, additional, Causse, Xavier, additional, Larrey, Dominique, additional, Chazouilleres, Olivier, additional, Gelu-Simeon, Moana, additional, Loustaud-Ratti, Véronique, additional, Metivier, Sophie, additional, Alric, Laurent, additional, Riachi, Ghassan, additional, Gournay, Jérôme, additional, Minello, Anne, additional, Tran, Albert, additional, Geist, Claire, additional, Abergel, Armand, additional, Raffi, François, additional, D'Alteroche, Louis, additional, Portal, Isabelle, additional, Lapidus, Nathanaël, additional, Pol, Stanislas, additional, and Carrat, Fabrice, additional
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- 2021
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31. Unresectable HCC patients disposal in the new era of immunotherapy from the elitor study based on the french chief cohort
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Nguyen-Khac, Eric, Nahon, Pierre, Ganry, Olivier, Ben Khadhra, Hajer, Merle, Philippe, Amaddeo, Giuliana, Ganne, Nathalie, Silvain, Christine, Peron, Jean-Marie, Mathurin, Philippe, Anty, Rodolphe, Uguen, Thomas, Riachi, Ghassan, Bouattour, Mohamed, Baron, Aurore, Gilberg, Melina, Tanang, Alexandre, Dupin, Julien, Ducournau, Gerard, Blanc, Jean-Frederic, DESSAIVRE, Louise, Groupe de Recherche sur l'alcool et les pharmacodépendances - UMR INSERM_S 1247 (GRAP), Université de Picardie Jules Verne (UPJV)-Institut National de la Santé et de la Recherche Médicale (INSERM), Hôpital Jean Verdier [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), CHU Amiens-Picardie, CHU Henri Mondor, Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Département de Santé Publique [Avicenne], Hôpital Avicenne [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centre hospitalier universitaire de Poitiers (CHU Poitiers), CHU Toulouse [Toulouse], Physiopathologie des Maladies Inflammatoires de l'Intestin, Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille, Droit et Santé, Centre méditerranéen de médecine moléculaire (C3M), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UCA), CHU Pontchaillou [Rennes], CHU Rouen, Normandie Université (NU), Hôpital Beaujon [AP-HP], Roche France, Département d'Oncologie [CHU Bordeaux] (Cancérologie/Oncologie/Digestive), and Hôpital Haut-Lévêque - CHU de Bordeaux (Centre médico chirurgical Magellan)-Hôpital Saint-André [CHU de Bordeaux]
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[SDV] Life Sciences [q-bio] ,[SDV]Life Sciences [q-bio] ,ComputingMilieux_MISCELLANEOUS - Abstract
International audience
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- 2021
32. Cannabis Use Is Inversely Associated with Overweight and Obesity in Hepatitis B Virus-Infected Patients (ANRS CO22 Hepather Cohort)
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Barré, Tangui, Pol, Stanislas, Ramier, Clémence, Di Beo, Vincent, Carrat, Fabrice, Bureau, Morgane, Bourlière, Marc, Dorival, Céline, Serfaty, Lawrence, Asselah, Tarik, Boursier, Jérôme, Marcellin, Fabienne, Carrieri, Patrizia, Fontaine, Hélène, Protopopescu, Camelia, Alric, Laurent, Bonnet, Delphine, Payssan-Sicart, Virginie, Pomes, Chloe, Zoulim, Fabien, Maynard, Marianne, Bai, Roxane, Hucault, Lucie, Bailly, François, Raffi, François, Billaud, Eric, Boutoille, David, Lefebvre, Maeva, André-Garnier, Elisabeth, Cales, Paul, Hubert, Isabelle, Lannes, Adrien, Lunel, Françoise, Boyer, Nathalie, Giuily, Nathalie, Castelnau, Corinne, Scoazec, Giovanna, Rousseaud, Emilie, Vallet-Pichard, Anaïs, Sogni, Philippe, Ledinghen, Victor De, Foucher, Juliette, Hiriart, Jean-Baptiste, M'Bouyou, Jancell, Irlès-Depé, Marie, Si Ahmed, Si Nafa, Oules, Valérie, Tran, Albert, Anty, Rodolphe, Gelsi, Eve, Truchi, Régine, Thabut, Dominique, Hammeche, Saloua, Moussali, Joseph, Causse, Xavier, Dieuleveult, Barbara De, Ouarani, Brahim, Labarrière, Damien, Ganne, Nathalie, Grando-Lemaire, Véronique, Nahon, Pierre, Brulé, Séverine, Ulker, Betul, Guyader, Dominique, Jezequel, Caroline, Brener, Audrey, Laligant, Anne, Rabot, Aline, Renard, Isabelle, Habersetzer, François, Baumert, Thomas, Doffoel, Michel, Mutter, Catherine, Simo-Noumbissie, Pauline, Razi, Esma, Bronowicki, Jean-Pierre, Barraud, Hélène, Bensenane, Mouni, Nani, Abdelbasset, Hassani-Nani, Sarah, Bernard, Marie-Albertine, Pageaux, Georges-Philippe, Larrey, Dominique, Meszaros, Magda, Metivier, Sophie, Bureau, Christophe, Morales, Thibault, Peron, Jean Marie, Robic, Marie Angèle, Decaens, Thomas, Faure, Marine, Froissart, Bruno, Hilleret, Marie-Noelle, Zarski, Jean-Pierre, Riachi, Ghassan, Goria, Odile, Paris, Fatima, Montialoux, Hélène, Leroy, Vincent, Amaddeo, Giuliana, Varaut, Anne, Simoes, Mélanie, Amzal, Rachida, Chazouillières, Olivier, Andreani, Tony, Angoulevant, Bénédicte, Chevance, Azeline, Samuel, Didier, Antonini, Teresa, Coilly, Audrey, Duclos Vallée, Jean-Charles, Tateo, Mariagrazia, Abergel, Armand, Reymond, Maud, Brigitte, Chanteranne, Benjamin, Buchard, Muti, Léon, Geist, Claire, Conroy, Guillaume, Riffault, Raphaëlle, Rosa, Isabelle, Barrault, Camille, Costes, Laurent, Hagège, Hervé, Loustaud-Ratti, Véronique, Carrier, Paul, Debette-Gratien, Maryline, Mathurin, Philippe, Lassailly, Guillaume, Lemaitre, Elise, Canva, Valérie, Dharancy, Sébastien, Louvet, Alexandre, Minello, Anne, Latournerie, Marianne, Bardou, Marc, Mouillot, Thomas, d'Alteroche, Louis, Barbereau, Didier, Nicolas, Charlotte, Elkrief, Laure, Jaillais, Anaïs, Gournay, Jérôme, Chevalier, Caroline, Archambeaud, Isabelle, Habes, Sarah, Portal, Isabelle, Gelu-Simeon, Moana, Saillard, Eric, Lafrance, Marie-Josée, Catherine, Lucie, Nutrition, obésité et risque thrombotique (NORT), Institut National de la Recherche Agronomique (INRA)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service d'hépatologie médicale [CHU Cochin], Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale (SESSTIM - U1252 INSERM - Aix Marseille Univ - UMR 259 IRD), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), ESIM - Déterminants Sociaux de la Santé et du Recours aux Soins (DS3), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service d'hépato-gastro-entérologie, Assistance Publique - Hôpitaux de Marseille (APHM), Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Hôpital de Hautepierre [Strasbourg], Service d’Hépatologie [Hôpital Beaujon], Hôpital Beaujon [AP-HP], Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC), and BOURGEAIS, Véronique
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Hepatitis B virus ,medicine.medical_specialty ,Cirrhosis ,[SDV]Life Sciences [q-bio] ,Aucun ,Overweight ,medicine.disease_cause ,Virus ,03 medical and health sciences ,Hepatitis B, Chronic ,0302 clinical medicine ,Internal medicine ,medicine ,Humans ,Pharmacology (medical) ,Obesity ,ComputingMilieux_MISCELLANEOUS ,Cannabis ,030304 developmental biology ,Pharmacology ,0303 health sciences ,biology ,Cannabinoids ,business.industry ,Liver Neoplasms ,Hepatitis B ,biology.organism_classification ,medicine.disease ,digestive system diseases ,3. Good health ,[SDV] Life Sciences [q-bio] ,Complementary and alternative medicine ,Hepatocellular carcinoma ,Cohort ,cannabis ,obesity ,overweight ,socioeconomic status ,030211 gastroenterology & hepatology ,medicine.symptom ,business - Abstract
International audience; Background: Chronic hepatitis B virus (HBV) infection may evolve into cirrhosis and hepatocellular carcinoma, and this progression may be accelerated by specific risk factors, including overweight and obesity. Although evidence for a protective effect of cannabis use on elevated body weight has been found for other populations, no data are available for HBV-infected patients.Aims: We aimed to identify risk factors (including cannabis use) for overweight and obesity in patients with HBV chronic infection.Methods: Using baseline data from the French ANRS CO22 Hepather cohort, we performed two separate analyses, one using “central obesity” (based on waist circumference) and the other “overweight” and “obesity” (based on body mass index) as outcomes. Logistic and multinomial regressions were used to model central obesity and overweight/obesity, respectively.Results: Among the 3706 patients in the study population, 50.8% had central obesity, 34.7% overweight, and 14.4% obesity. After multivariable adjustment, current cannabis use was associated with a 59% lower risk of central obesity compared with no lifetime use (adjusted odds ratio [95% CI]: 0.41 [0.24 to 0.70]). It was also associated with a 54% and 84% lower risk of overweight (adjusted relative risk ratio [95% CI]: 0.46 [0.27 to 0.76]) and obesity (0.16 [0.04 to 0.67]), respectively.Conclusions: Cannabis use was associated with lower risks of overweight and obesity in patients with HBV chronic infection. Future studies should test whether these potential benefits of cannabis and cannabinoid use translate into reduced liver disease progression in this high-risk population.
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- 2021
33. Late supra-diaphragmatic lymph node recurrence following resection of a fibrolamellar hepatocarcinoma: an unusual case
- Author
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Tsilividis, Basile, Huet, Emmanuel, Lubrano, Jean, Lacaze, Laurence, Lestrat, Jean Pierre, François, Arnaud, Riachi, Ghassan, and Scotté, Michel
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- 2010
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34. Including Ratio of Platelets to Liver Stiffness Improves Accuracy of Screening for Esophageal Varices That Require Treatment
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Berger, Arthur, primary, Ravaioli, Federico, additional, Farcau, Oana, additional, Festi, Davide, additional, Stefanescu, Horia, additional, Buisson, François, additional, Nahon, Pierre, additional, Bureau, Christophe, additional, Ganne-Carriè, Nathalie, additional, Berzigotti, Annalisa, additional, de Ledinghen, Victor, additional, Petta, Salvatore, additional, Calès, Paul, additional, Huvelin, Sylvie Sacher, additional, Valla, Dominique, additional, Olivier, Anne, additional, Oberti, Frédéric, additional, Boursier, Jérôme, additional, Galmiche, Jean Paul, additional, Vinel, Jean Pierre, additional, Duburque, Clotilde, additional, Attar, Alain, additional, Archambeaud, Isabelle, additional, Benamouzig, Robert, additional, Gaudric, Marianne, additional, Luet, Dominique, additional, Couzigou, Patrice, additional, Planche, Lucie, additional, Coron, Emmanuel, additional, Hiriart, Jean-Baptiste, additional, Chermak, Faiza, additional, Charbonnier, Maude, additional, Marcellin, Patrick, additional, Guyader, Dominique, additional, Pol, Stanislas, additional, Fontaine, Hélène, additional, Larrey, Dominique, additional, De Lédinghen, Victor, additional, Ouzan, Denis, additional, Zoulim, Fabien, additional, Roulot, Dominique, additional, Tran, Albert, additional, Bronowicki, Jean-Pierre, additional, Zarski, Jean-Pierre, additional, Leroy, Vincent, additional, Riachi, Ghassan, additional, Péron, Jean-Marie, additional, Alric, Laurent, additional, Bourlière, Marc, additional, Mathurin, Philippe, additional, Dharancy, Sebastien, additional, Blanc, Jean-Frédéric, additional, Abergel, Armand, additional, Serfaty, Lawrence, additional, Mallat, Ariane, additional, Grangé, Jean-Didier, additional, Attali, Pierre, additional, Bacq, Yannick, additional, Wartelle, Claire, additional, Dao, Thông, additional, Benhamou, Yves, additional, Pilette, Christophe, additional, Silvain, Christine, additional, Christidis, Christos, additional, Capron, Dominique, additional, Thiefin, Gérard, additional, Hillaire, Sophie, additional, and Di Martino, Vincent, additional
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- 2021
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35. Long-Term Outcome of Liver Resection for Hepatocellular Carcinoma in Noncirrhotic Nonfibrotic Liver with No Viral Hepatitis or Alcohol Abuse
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Lubrano, Jean, Huet, Emmanuel, Tsilividis, Basile, François, Arnaud, Goria, Odile, Riachi, Ghassan, and Scotté, Michel
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- 2008
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36. OS-081 - Epidemiology and characteristics of hepatocellular carcinoma in France: results of the first 2000 patients in real-life situations from the French prospective chief cohort
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Khac, Eric Nguyen, Merle, Philippe, Hajer, Ben Khadhra, Amaddeo, Giuliana, Decaens, Thomas, Uguen, Thomas, Blanc, Jean-Frédéric, Ganne-Carrié, Nathalie, Bouattour, Mohamed, Cattan, Stéphane, Silvain, Christine, Riachi, Ghassan, Peron, Jean Marie, Anty, Rodolphe, Bronowicki, Jean-Pierre, Baron, Aurore, Pageaux, Georges-Philippe, Loustaud-Ratti, Veronique, Oberti, Frédéric, Allaire, Manon, Manfredi, Sylvain, Merabet, Yasmina Ben, Ollivier-Hourmand, Isabelle, Lequoy, Marie, Nousbaum, Jean Baptiste, Gelu-Simeon, Moana, Grados, Lucien, Nahon, Pierre, Costentin, Charlotte, Ducournau, Gerard, and Ganry, Olivier
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- 2023
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37. Personalized surveillance for hepatocellular carcinoma in cirrhosis – using machine learning adapted to HCV status
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Audureau, Etienne, primary, Carrat, Fabrice, additional, Layese, Richard, additional, Cagnot, Carole, additional, Asselah, Tarik, additional, Guyader, Dominique, additional, Larrey, Dominique, additional, De Lédinghen, Victor, additional, Ouzan, Denis, additional, Zoulim, Fabien, additional, Roulot, Dominique, additional, Tran, Albert, additional, Bronowicki, Jean-Pierre, additional, Zarski, Jean-Pierre, additional, Riachi, Ghassan, additional, Calès, Paul, additional, Péron, Jean-Marie, additional, Alric, Laurent, additional, Bourlière, Marc, additional, Mathurin, Philippe, additional, Blanc, Jean-Frédéric, additional, Abergel, Armand, additional, Chazouillères, Olivier, additional, Mallat, Ariane, additional, Grangé, Jean-Didier, additional, Attali, Pierre, additional, d'Alteroche, Louis, additional, Wartelle, Claire, additional, Dao, Thông, additional, Thabut, Dominique, additional, Pilette, Christophe, additional, Silvain, Christine, additional, Christidis, Christos, additional, Nguyen-Khac, Eric, additional, Bernard-Chabert, Brigitte, additional, Zucman, David, additional, Di Martino, Vincent, additional, Sutton, Angela, additional, Pol, Stanislas, additional, and Nahon, Pierre, additional
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- 2020
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38. Kinetics of relapse after pegylated interferon and ribavirin therapy for chronic hepatitis C
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Brochot, Etienne, Riachi, Ghassan, Plantier, Jean-Christophe, Guillemard, Catherine, Vabret, Astrid, Mathurin, Philippe, Nguyen-Khac, Eric, and Duverlie, Gilles
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- 2013
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39. Safety and efficacy of telaprevir or boceprevir in combination with peginterferon alfa/ribavirin, in 455 cirrhotic non responders. Week 16 analysis of the French early access program (ANRS CO20-CUPIC) in real-life setting: 51
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Hezode, Christophe, Dorival, Celine, Zoulim, Fabien, Larrey, Dominique G., Pol, Stanislas, Cacoub, Patrice, Canva, Valerie, Poynard, Thierry, Samuel, Didier, Bourliere, Marc, Alric, Laurent, Raabe, Jean-Jacques, Zarski, Jean-Pierre H., Riachi, Ghassan, Bernard, Pierre-Henri, de Ledinghen, Victor, Loustaud-Ratti, Veronique, Metivier, Sophie, Causse, Xavier, Marcellin, Patrick, Barthe, Yann, Fontaine, Hélène, Carrat, Fabrice, and Bronowicki, Jean-Pierre
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- 2012
40. Origin, HDV genotype and persistent viremia determine outcome and treatment response in patients with chronic hepatitis delta
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Roulot, Dominique, primary, Brichler, Ségolène, additional, Layese, Richard, additional, BenAbdesselam, Zahia, additional, Zoulim, Fabien, additional, Thibault, Vincent, additional, Scholtes, Caroline, additional, Roche, Bruno, additional, Castelnau, Corinne, additional, Poynard, Thierry, additional, Chazouillères, Olivier, additional, Ganne, Nathalie, additional, Fontaine, Hélène, additional, Gournay, Jerome, additional, Guyader, Dominique, additional, Le Gal, Frédéric, additional, Nahon, Pierre, additional, Roudot-Thoraval, Françoise, additional, Gordien, Emmanuel, additional, Grangé, Jean-Didier, additional, Landman, Roland, additional, Hezode, Christophe, additional, Riachi, Ghassan, additional, Lascoux-Combe, Caroline, additional, Loustaud-Ratti, Véronique, additional, Rosa, Isabelle, additional, Mathurin, Philippe, additional, Nguyen-Khac, Eric, additional, Causse, Xavier, additional, Naveau, Sylvie, additional, Habersetzer, François, additional, Metivier, Sophie, additional, Labadie, Hélène, additional, Sellier, Pierre, additional, Bottero, Julie, additional, de Ledinghen, Victor, additional, Alric, Laurent, additional, Calès, Paul, additional, Goujard, Cecile, additional, Cadranel, Jean-François, additional, Salmon, Dominique, additional, and Hillaire, Sophie, additional
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- 2020
- Full Text
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41. Prognosis of alcoholic or viral B/C cirrhosis according to ABO blood group: results of abocirralvir, from CIRRAL and ANRS CO12 CirVir cohorts
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Ollivier-Hourmand, Isabelle, primary, Nahon, Pierre, additional, Chaffaut, Cendrine, additional, Dao, Thong, additional, Nguyen, Nga, additional, Patrick, Marcellin, additional, Roulot, Dominique, additional, de Lédinghen, Victor, additional, Pol, Stanislas, additional, Guyader, Dominique, additional, Mabile-Archambeaud, Isabelle, additional, Zoulim, Fabien, additional, Oberti, Frédéric, additional, Tran, Albert, additional, Bronowicki, Jean-Pierre, additional, Dalteroche, Louis, additional, Ouzan, Denis, additional, Peron, Jean Marie, additional, Zarski, Jean-Pierre, additional, Bourliere, Marc, additional, Larrey, Dominique, additional, Louvet, Alexandre, additional, Cales, Paul, additional, Abergel, Armand, additional, Mathurin, Philippe, additional, Mallat, Ariane, additional, Blanc, Jean-Frédéric, additional, Khac, Eric Nguyen, additional, Riachi, Ghassan, additional, Alric, Laurent, additional, Serfaty, Lawrence, additional, Antonini, Tereza, additional, Moreno, Christophe, additional, Attali, Pierre, additional, Thabut, Dominique, additional, Pilette, Christophe, additional, Grange, Jean Didier, additional, Silvain, Christine, additional, Carbonell, Nicolas, additional, Chabert, Brigitte Bernard, additional, Goria, Odile, additional, Wartelle-Bladou, Claire, additional, Moirand, Romain, additional, Christidis, Christos, additional, Perlemuter, Gabriel, additional, Ozenne, Violaine, additional, Henrion, Jean, additional, Hillaire, Sophie, additional, Di Martino, Vincent, additional, Amiot, Xavier, additional, Sutton, Angela, additional, Barget, Nathalie, additional, Repesse, Yohann, additional, Chevret, Sylvie, additional, and Ganne-Carrié, Nathalie, additional
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- 2020
- Full Text
- View/download PDF
42. Anxiety and Depression Profile Is Associated With Eating Disorders in Patients With Irritable Bowel Syndrome
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Melchior, Chloé, primary, Desprez, Charlotte, additional, Riachi, Ghassan, additional, Leroi, Anne-Marie, additional, Déchelotte, Pierre, additional, Achamrah, Najate, additional, Ducrotté, Philippe, additional, Tavolacci, Marie-Pierre, additional, and Gourcerol, Guillaume, additional
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- 2020
- Full Text
- View/download PDF
43. Circulating DNA changes are predictive of disease progression after transarterial chemoembolization.
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Sefrioui, David, Verdier, Vincent, Savoye‐Collet, Céline, Beaussire, Ludivine, Ghomadi, Slim, Gangloff, Alice, Goria, Odile, Riachi, Ghassan, Montialoux, Hélène, Schwarz, Lilian, Tuech, Jean‐Jacques, Frebourg, Thierry, Michel, Pierre, Sarafan‐Vasseur, Nasrin, and Di Fiore, Frédéric
- Subjects
CIRCULATING tumor DNA ,CELL-free DNA ,CHEMOEMBOLIZATION ,MAGNETIC resonance imaging ,HEPATOCELLULAR carcinoma ,RECEIVER operating characteristic curves ,DISEASE progression - Abstract
Transarterial chemoembolization (TACE) is used to treat patients with unresectable hepatocellular carcinoma (HCC). We evaluated the clinical impact of a‐fetoprotein (AFP) and circulating cell‐free and tumor DNA (cfDNA and ctDNA) changes around the TACE procedure. Our prospective monocentric study enrolled consecutive patients treated with TACE, with samples collected at baseline (D − 1), Day 2 (D + 2) and 1 month (M + 1) after TACE. cfDNA was quantified by the fluorometric method, and ctDNA was quantified by digital polymerase chain reaction designed for two hotspot TERT mutations. Computerized tomography scans or magnetic resonance imaging were performed at M + 1 every 3 months following TACE and independently reviewed. The objective was to identify thresholds of cfDNA, ctDNA and AFP changes associated with progressive disease (PD) using receiver operating characteristic curves. Thirty‐eight patients were included from March 2018 to March 2019. All markers significantly increased from D − 1 to D + 2 (P <.005), and cfDNA and ctDNA significantly decreased from D + 2 to M + 1 (P <.0001). The analysis of changes from D − 1 to M + 1 identified thresholds at +31.4% for cfDNA and 0% for ctDNA that were significantly associated with PD at M + 1 (44.4% [>+31.4%] vs 3.8% [≤+31.4%] and 50.0% [>0%] vs 5.0% [≤0%], respectively). No significant threshold was identified for AFP. Using a score combining cfDNA and ctDNA, the patients were classified into high‐ or low‐risk PD groups at M + 1, with PD rates of 80.0% vs 4.3% (P =.001) and median progression‐free survival times of 1.3 vs 10.3 months (P =.002). Our study suggests that cfDNA and ctDNA increases around the TACE procedure and are associated with therapeutic failure. What's new? Transarterial chemoembolization (TACE) is recommended as the first line of treatment for intermediate‐stage hepatocellular carcinoma, but efficacy assessment methods need to be improved. This prospective study evaluates the clinical impact of a‐fetoprotein and circulating cell‐free and tumor DNA changes around the TACE procedure. The results suggest that circulating cell‐free and tumor DNA dynamics may represent a promising marker to help evaluate treatment strategies after a first TACE procedure. A significant peak release of circulating DNA markers was observed after TACE, with a circulating tumor DNA detection rate at Day 2 that was almost twice as high as that at baseline. [ABSTRACT FROM AUTHOR]
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- 2022
- Full Text
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44. Anxiety and Depression Profile Is Associated With Eating Disorders in Patients With Irritable Bowel Syndrome
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Melchior, Chloé, Desprez, Charlotte, Riachi, Ghassan, Leroi, Anne-Marie, Déchelotte, Pierre, Achamrah, Najate, Ducrotté, Philippe, Tavolacci, Marie-Pierre, Gourcerol, Guillaume, Service d'Hépato-Gastroentérologie [CHU Rouen], Hôpital Charles Nicolle [Rouen]-CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), Nutrition, inflammation et dysfonctionnement de l'axe intestin-cerveau (ADEN), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institute for Research and Innovation in Biomedicine (IRIB), Normandie Université (NU)-Normandie Université (NU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM), UNIROUEN - UFR Santé (UNIROUEN UFR Santé), Normandie Université (NU)-Normandie Université (NU), Service de physiologie digestive, urinaire, respiratoire et de l'exercice [CHU Rouen], CHU Rouen, Normandie Université (NU)-Hôpital Charles Nicolle [Rouen], Centre d'Investigation Clinique [CHU Rouen] (CIC Rouen), Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de nutrition [CHU Rouen], and Normandie Université (NU)-Normandie Université (NU)-CHU Rouen
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Psychiatry ,healthy volunteers ,quality of life ,stressful life events ,Rome III criteria ,body mass index (BMI) ,validated self-questionnaires ,[SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology ,ComputingMilieux_MISCELLANEOUS ,Original Research - Abstract
Objective: To compare the prevalence of anxiety and depression states and eating disorders (EDs) between patients with irritable bowel syndrome (IBS) and healthy volunteers without IBS. Methods: IBS patients according to Rome III criteria referred to our tertiary care center for therapeutic management and matched volunteers without IBS were prospectively included. EDs were screened by Sick, Control, One stone, Fat, Food—French version (SCOFF-F) questionnaire. IBS symptom severity (IBS symptom severity score), stool consistency (Bristol stool scale), anxiety and depression levels (Hospital Anxiety and Depression scale), and quality of life (validated Gastrointestinal Quality of Life Index) were assessed by validated self-questionnaires. Results: IBS (228) patients and healthy volunteers (228) were included. Mean age was 42.5 ± 13.9 years with mainly women (76.7%). Among IBS patients, 25.4% had positive SCOFF-F compared to 21.1% of volunteers. IBS patients more frequently had a lower body mass index (BMI) than volunteers (p < 0.0001). IBS patients with ED had poorer quality of life and more stressful life events (p = 0.02) than IBS patients without ED. The prevalence of anxiety and depression was significantly higher in IBS patients with ED than in volunteers without ED, respectively (19.0% vs 1.9%, p=0.00, and 60.3% vs 19.7%, p < 0.0001). Conclusions: The prevalence of ED assessed with positive SCOFF-F questionnaire was not significantly different between IBS patients and healthy volunteers. The combination of IBS and ED was associated with higher levels of anxiety or depression and poorer quality of life.
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- 2019
45. Non-virological factors are drivers of hepatocellular carcinoma in virosuppressed hepatitis B cirrhosis: Results of ANRS CO12 CirVir cohort
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Brichler, Ségolène, Nahon, Pierre, Zoulim, Fabien, Layese, Richard, Bourcier, Valérie, Audureau, Etienne, Sutton, Angela, Letouzé, Eric, Cagnot, Carole, Marcellin, Patrick, Guyader, Dominique, Roulot, Dominique, Pol, Stanislas, de Ledinghen, Victor, Zarski, Jean-Pierre, Calès, Paul, Tran, Albert, Peron, Jean-Marie, Mallat, Ariane, Riachi, Ghassan, Grangé, Jean-Didier, Blanc, Jean-Frederic, Bacq, Yannick, Ouzan, Denis, Bronowicki, Jean-Pierre, Mathurin, Philippe, Larrey, Dominique, Alric, Laurent, Attali, Pierre, Serfaty, Lawrence, Pilette, Christophe, Bourlière, Marc, Thabut, Dominique, Silvain, Christine, Wartelle, Claire, Zucman, David, Christidis, Christos, Roudot-Thoraval, Françoise, Ganne-Carrie, Nathalie, (anrs Co22 Hepather, Co12 Cirvir And Co23 Cupilt Cohorts), Anrs Collaborative Study Group On Hepatocellular Carcinoma, Molecular virology and immunology – Physiopathology and therapeutic of chronic viral hepatitis (Team 18) (Inserm U955), Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Service de Microbiologie Clinique [Hôpital Avicenne - APHP], Hôpital Avicenne [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service d'Hépato-gastroentérologie, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Jean Verdier [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centre de recherche biomédicale Bichat-Beaujon (CRB3), Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Génomique Fonctionnelle des Tumeurs Solides (U1162), Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre de Recherche en Cancérologie de Lyon (UNICANCER/CRCL), Centre Léon Bérard [Lyon]-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Clinical Epidemiology and Ageing : Geriatrie Soins Primaires et Santé Publique (CEpiA), Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Service d'Hépatologie, Université Paris 13 (UP13)-Hôpital Jean Verdier [AP-HP], Service de santé publique [Mondor], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Laboratoire de Recherche Vasculaire Translationnelle (LVTS (UMR_S_1148 / U1148)), Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), ANRS France Recherche Nord & sud Sida-hiv hépatites, Centre de recherche sur l'Inflammation (CRI (UMR_S_1149 / ERL_8252 / U1149)), Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), CHU Pontchaillou [Rennes], Service de gastroenterologie, Physiopathologie du Système Immunitaire, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Service d'Hépato-Gastro-Entérologie, CHU Bordeaux [Bordeaux]-Hôpital Saint-André, Hôpital Michallon, Département d'hépato-gastroentérologie, CHU Grenoble-Université Grenoble Alpes (UGA), Hémodynamique, Interaction Fibrose et Invasivité tumorales Hépatiques (HIFIH), Université d'Angers (UA), Centre méditérannéen de médecine moléculaire (C3M), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Toulouse [Toulouse], Institut Mondor de recherche biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), CHU Rouen, Normandie Université (NU), CHU Tenon [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Physiopathologie du cancer du foie, Université Bordeaux Segalen - Bordeaux 2-Institut National de la Santé et de la Recherche Médicale (INSERM), Département d'hépato-gastro-entérologie [Hôpital Trousseau : CHRU Tours], CHU Trousseau [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Institut Arnault Tzanck, Nutrition-Génétique et Exposition aux Risques Environnementaux (NGERE), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Inflammation: mécanismes et régulation et interactions avec la nutrition et les candidoses, Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille, Droit et Santé, Cellules Souches, Plasticité Cellulaire, Médecine Régénératrice et Immunothérapies (IRMB), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Pharmacochimie et Biologie pour le Développement (PHARMA-DEV), Institut de Recherche pour le Développement (IRD)-Institut de Chimie de Toulouse (ICT-FR 2599), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées, Hôpital Paul Brousse, Hôpital de Hautepierre [Strasbourg], Centre Hospitalier Le Mans (CH Le Mans), Hôpital Saint-Joseph [Marseille], CHU Pitié-Salpêtrière [AP-HP], Department of Hepatology and Gastroenterology, CHU de Poitiers, Centre Hospitalier d'Aix en Provence [Aix-en-Provence] (CHIAP ), Hôpital Foch [Suresnes], Institut Mutualiste de Montsouris (IMM), Assistance Publique Hôpitaux de Paris, Hôpitaux Universitaires Paris – Seine Saint-Denis, Site Jean Verdier, Pôle d’Activité Cancérologique Spécialisée, Service d’Hépatologie, F-93143 Bondy, France, ANRS. Grant Number: 15275, Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM), Hôpital Jean Verdier [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris 13 (UP13), Service d'hépatologie [CHU Pontchaillou], Université Grenoble Alpes (UGA)-CHU Grenoble, Université Nice Sophia Antipolis (... - 2019) (UNS), Hôpital Purpan [Toulouse], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centre Hospitalier Régional Universitaire de Tours (CHRU Tours)-CHU Trousseau [APHP], Université de Lille, Droit et Santé-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Montpellier (UM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Service de Médecine Interne [Purpan], CHU Toulouse [Toulouse]-Hôpital Purpan [Toulouse], École Pratique des Hautes Études (EPHE), Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Institut de Recherche pour le Développement (IRD)-Institut de Chimie de Toulouse (ICT), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT), Université Paris Diderot - Paris 7 (UPD7)-Université Paris 13 (UP13)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur [Paris], and Centre Hospitalier Régional Universitaire de Tours (CHRU TOURS)-CHU Trousseau [APHP]
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Liver Cirrhosis ,Male ,HBsAg ,Sustained Virologic Response ,[SDV]Life Sciences [q-bio] ,Kaplan-Meier Estimate ,medicine.disease_cause ,Gastroenterology ,0302 clinical medicine ,Risk Factors ,Surveys and Questionnaires ,Prospective Studies ,030212 general & internal medicine ,Prospective cohort study ,2. Zero hunger ,Liver Neoplasms ,Hepatitis C ,Middle Aged ,Hepatitis B ,3. Good health ,Infectious Diseases ,Hepatocellular carcinoma ,ANRS CO12 CirVir ,Female ,030211 gastroenterology & hepatology ,Viral hepatitis ,carcinogenesis ,Hepatitis B virus ,medicine.medical_specialty ,Carcinoma, Hepatocellular ,Genotype ,risk score ,Antiviral Agents ,03 medical and health sciences ,Virology ,Internal medicine ,medicine ,Humans ,Proportional Hazards Models ,Hepatitis ,Hepatitis B Surface Antigens ,Hepatology ,business.industry ,medicine.disease ,digestive system diseases ,prognosis ,viral cirrhosis ,business - Abstract
International audience; Worldwide, hepatocellular carcinoma (HCC) occurs mainly in Asian patients with hepatitis B virus (HBV) infection. This study aimed to decipher the environmental and virological factors associated with HCC occurrence and validate risk scoring systems in a French multicentre prospective cohort of HBV cirrhotic patients. Patients with biopsy‐proven Child‐Pugh A viral cirrhosis included in the ANRS CO12 CirVir cohort who were HBsAg(+) without hepatitis C coinfection were selected for: (a) interview through a standardized questionnaire reporting coffee consumption and HCC familial history; (b) HBsAg quantification using baseline and sequential 2‐year frozen sera; (c) baseline HBV genotype determination; and (d) assessment of risk factors and applicability of HCC risk scores (Kaplan‐Meier analysis, Cox models). Among 317 patients studied (261 men, median age 53 years, past or ongoing antiviral treatment 93.3% and baseline detectable HBV DNA in 88 patients), the baseline and 2‐year median HBsAg levels were 810 and 463 IU/mL, respectively. After a median follow‐up of 65.2 months, 27 HCC cases were diagnosed (annual incidence: 1.6%). Three factors were independently associated with HCC occurrence: age > 50 years, platelets ≤ 150 × 103/mm3 and body mass index ≥ 30 kg/m2. Two out of five risk scores were validated, and the most accurate was PAGE‐B at 1 year. Moreover, HCC in patients without maintained virological suppression seems more aggressive and less accessible to curative treatment. In conclusion, in French patients with HBV cirrhosis mostly virally suppressed, independent HCC risk factors were host‐related (age, obesity) or linked to the severity of cirrhosis (thrombopenia), and the European PAGE‐B score was the most accurate risk score.
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- 2019
46. Inflammatory pseudotumor of the liver revealing gynecological Corynebacterium infection
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BERNARD, MATHIEU, MARIE, ISABELLE, RIACHI, GHASSAN, GORIA, ODILE, LEREBOURS, ERIC, FRANÇOIS, ARNAUD, LEVESQUE, HERVÉ, and MICHEL, PIERRE
- Published
- 2005
47. Pseudo-Angiocholitis Revealing Adult-Onset Stillʼs Disease
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MARIE, ISABELLE, DUCROTTÉ, PHILIPPE, RIACHI, GHASSAN, FRANÇOIS, ARNAUD, LEVESQUE, HERVÉ, and COURTOIS, HUBERT
- Published
- 2004
48. Characteristics of chronic hepatitis C and response to interferon therapy in older patients
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HERVÉ, SOPHIE, SAVOYE, GUILLAUME, RIACHI, GHASSAN, CAPET, CORINNE, GORIA, ODILE, LEREBOURS, ERIC, and COLIN, RAYMOND
- Published
- 2001
49. Prognostic value of the soluble interleukin-2 receptor in chronic hepatitis C treated with interferon-alfa
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Naveau, Sylvie, Balian, Axel, Degos, Françoise, Daurat, Véronique, Chevret, Sylvie, Gayno, Sophie, Bastie, Anne, Riachi, Ghassan, Bartolomei-Portal, Isabelle, Barange, Karl, Moussalli, Joseph, Bailly, François, Chaumet-Riffaud, Philippe, and Emilie, Dominique
- Published
- 1999
50. THU-152-New in France: Universal access for HCV-treatment as demonstrated by a nationwide real-world cohort
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Larrey, Dominique, primary, Pol, Stanislas, additional, Remy, André-Jean, additional, Dumortier, Jérôme, additional, Hézode, Christophe, additional, Bronowicki, Jean-Pierre, additional, Jezequel, Caroline, additional, Grangé, Jean-Didier, additional, Thabut, Dominique, additional, Ledinghen, Victor De, additional, Renou, Christophe, additional, Heluwaert, Frédéric, additional, Riachi, Ghassan, additional, Truchi, Régine, additional, Rosa, Isabelle, additional, Bailly, François, additional, Glorian-Kergavarat, Denise, additional, Libert, Olivier, additional, Bonnard, Philippe, additional, and Ouzan, Denis, additional
- Published
- 2019
- Full Text
- View/download PDF
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