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The cross-cultural adaptation and validation of the Sniffin`Sticks test for the Portuguese population is described. Over 270 people participated in four experiments. In Experiment 1, 67 participants rated the familiarity of presented odors and seven descriptors of the original test were adapted to a Portuguese context. In Experiment 2, the Portuguese version of Sniffin`Sticks test was administered to 203 healthy participants. Older age, male gender and active smoking status were confirmed as confounding factors. The third experiment showed the validity of the Portuguese version of Sniffin`Sticks test in discriminating healthy controls from patients with olfactory dysfunction. In Experiment 4, the test-retest reliability for both the composite score (r71 = 0.86) and the identification test (r71 = 0.62) was established (p<0.001). Normative data for the Portuguese version of Sniffin`Sticks test is provided, showing good validity and reliability and effectively distinguishing patients from healthy controls with high sensitivity and specificity. The Portuguese version of Sniffin`Sticks test identification test is a clinically suitable screening tool in routine outpatient Portuguese settings. [ABSTRACT FROM AUTHOR]

Keywords: allergic contact dermatitis; bone conduction implant; case report; titanium EN allergic contact dermatitis bone conduction implant case report titanium 148 149 2 07/27/20 20200801 NES 200801 Bone conduction implantation (BONEBRIDGE) is a revolutionary method for hearing rehabilitation in patients with conductive and mixed hearing loss. The patient had previously suffered a prolonged healing process after the implantation of a percutaneous implant (BAHA), also composed of titanium. The BONEBRIDGE device is a bone conduction implant, which is composed of titanium and partially covered with silicone. [Extracted from the article]

Vertigo is an illusionary sensation of movement, which is frequently accompanied by great discomfort and distressing vegetative reactions. Dizziness caused by vestibular dysfunction involves psychological reactions. These reactions can vary considerably depending on whether or not psychiatric patients are involved. Vertigo may also be a symptom of a psychiatric disorder with no objective symptoms of a disorder of the vestibular system or of other neurological pathologies. This dichotomy in which psychological issues are the cause or the consequence of dizziness represents a possible incomplete view of the disorder, leading to sub-optimal care. Typically, otoneurologic disorders and psychiatric disorders coexist and interact, probably as a result of central-neurologic links between the vestibular and the autonomic systems. [ABSTRACT FROM AUTHOR]

Usher Syndrome classification takes into account the absence of vestibular function but its correlation with genotype is not well characterized. We intend to investigate whether video Head Impulse Test (vHIT) is useful in screening and to differentiate Usher Syndrome types. 29 Usher patients (USH) with a genetically confirmed diagnosis and 30 healthy controls were studied with vHIT and dizziness handicap inventory questionnaire (DHI). Statistical significant differences between USH1, USH2 and controls were found in the vestibulo-ocular-reflex (VOR) gain of all SCCs, with USH1 patients consistently presenting smaller gains. VOR gain of the right lateral SCC could discriminate controls from USH1, and USH2 from USH1 with an overall diagnostic accuracy of 90%. USH1 DHI correlated with VOR (ρ = − 0,971, p = 0.001). Occurrence rate of covert and overt lateral semicircular canals refixation saccades (RS) was significantly different between groups, being higher in USH1 patients (p < 0.001). USH1 peak velocity of covert and overt saccades was higher for lateral semicircular canals (p < 0.05 and p = 0.001) compared with USH2 and controls. Covert saccades occurrence rate for horizontal SCCs could discriminate USH1 from USH2 patients and controls with a diagnostic accuracy of 85%. vHIT is a fast and non-invasive instrument which allowed us to screen and distinguish Usher patients from controls with a high precision. Importantly, its use allowed further discrimination between USH1 from USH2 groups. Moreover, VOR gain seems to correlate with vertigo-related quality of life in more severe phenotypes. [ABSTRACT FROM AUTHOR]

Introduction: Gingival recession (GR) is a relevant clinical condition due to its high prevalence worldwide, which leads to aesthetic demands and dentin hypersensitivity. Collagen matrices have been associated with different designs of coronally advanced flaps (CAFs) to treat GR defects. However, the literature lacks long‐term follow‐up of this treatment option. The aim of this study is to present the long‐term follow‐up (up to 7 years) of two GR defects (associated or not with noncarious cervical lesion) treated with a CAF and a collagen matrix (CM). Case presentation: Case 1 underwent a CAF associated with a CM to treat a single GR defect. After 7 years, Case 1 presented with 3 mm of recession reduction, which corresponds with the 85.7% of root coverage. Case 2 presented two GR defects associated with noncarious cervical lesions (NCCLs). The NCCLs were partially restored with resin composite and then underwent a modified CAF for multiple defects and a CM. After 5 years of follow‐up, Case 2 presented with 1.5 and 2.5 mm of recession reduction, which corresponds with the average 83.3% defect coverage. Conclusion: These two cases may show that CMs can provide long‐term stable outcomes in the treatment of GR defects. Why is this case new information?One of the cases is the first one to describe a 7 years of follow‐up after CAF+CM to treat gingival recession defects. What are the keys to successful management of this case?Correct material handling.Adequate restorative protocol and surgical technique. What are the primary limitations to success in this case?DiagnosePatient compliance. [ABSTRACT FROM AUTHOR]

We evaluated the efficacy of Bioverm®, a commercial product containing Duddingtonia flagrans , on the control of buffalo (Bubalus bubalis) gastrointestinal nematodes. We randomly divided 12 buffaloes into two groups of six animals. In the treated group, each animal received a Bioverm®ˋs single dose of 1g (105 chlamydospores of D. flagrans) to 10 kg of live weight; in the control group, each animal received 1g of corn bran for each 10 kg of live weight as a placebo. Fecal samples were individually collected from 12, 24, 36, 48, 60 and 72 h after treatments. To examine 1) viability of chlamydospores passed through the gastrointestinal tract, 2 g of faeces and 1000 infective larvae (L3) were added to Petri dishes with 2% water-agar, and 2) to examine larval predation by D. flagrans during fecal cultures, 2000 L3 were added. In the Petri dishes, were observed significant reductions (p < 0.01) in the treated group after 48 (56.7%) and 60 h (91.5%). In the fecal cultures, significant reductions (p < 0.01) occurred in the treated group from 36 h (75%), with larval reduction up to 72 h. High larval predation rate occurred 60 h after Bioverm® administration. Bioverm® maintained viability and predation capacity after passage through the buffalo's gastrointestinal tract, showing efficacy on gastrointestinal nematodes. • First report of the effect of Bioverm® on buffalo gastrointestinal parasites. • Viability of Bioverm® after passage through the buffalo's gastrointestinal tract. • Larval predation rates up to 91.5% in the treated group. • High larval predation at 60 h after product administration. [ABSTRACT FROM AUTHOR]