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Background: Devices that use light, especially lasers, have become popular and are commonly used in aesthetics and hair removal. Laser-assisted photo epilation was originally described in 1996 and the proposed mechanism is based on the destruction of the follicular unit. Diode laser has been demonstrated to be an effective method for hair removal, however, the safety of patients with different skin types and colours is questionable due to thermal damage as the main side-effect. In this sense, the technological innovation of Photoepilation using high power LED equipment with high head cooling efficiency represents a great advance for the area. In this work, we evaluated the results of photoepilation using high-power LED in 117 patients with phototypes 01 to 06. Methods: A High potency LED equipment (Holoniak® -- Adoxy Equipments -- Brazil) was used. The LED allows the therapist to customize illumination parameters according to the sensitivity of the patients. All 117 participants were submitted to an initial sensitivity test to the LED irradiation, in order to determine adequate parameters to each participant. Sensitivity test was performed in both stationary and scanning modes. In scanning mode the test started with the following parameters -- temperature of the at 10oC, fluence of 5 J/Cm2 and frequency 2 -- 3 Hz. In stationary mode the sensitivity test started with temperature of the probe at 10 oC, fluence of 10 J/Cm2 and frequency of 0.8 Hz. No phototype restrictions were applied. To analyze the satisfaction of results, we created an arbitrary scale ranging from 1 to 4, where Grade 1 was considered unsatisfactory, Grade 2 - little satisfactory, Grade 3 - satisfactory and Grade 4 - very satisfactory. We also analyzed the number of sessions needed to achieve the hair removal result for each skin phototype. Results: Analyzing the percentage of satisfaction after LED photoepilation, satisfaction grade 3 and 4 represent approximately 95% of the participants. Surprisingly, there was no statistical correlation between the increase in skin phototype and the number of sessions needed to achieve the complete photoepilation effect. Unlike laser technology, which usually requires a high number of sessions for higher phototypes. No correlation with age was also reported. Conclusion: We can conclude that high power LED technology with effective tip cooling was able to achieve highly efficient results for 95.7% of treated patients, without the need to increase the number of sessions for phototypes 4 to 6. [ABSTRACT FROM AUTHOR]

Background: Generally, in the aging process, there is degradation of autonomic nervous control mechanisms, compromising the regulation of heart rate, which contributes to increased frailty and the risk of falls. This process is defined as a geriatric syndrome that leads to impairment of physiological systems and homeostatic imbalance. Objective: To correlate heart rate variability (HRV), frailty parameters, and the risk of falls in elderly people from a community center. Methods: This research will involve active seniors and participants from the Centro de Convivências de Praia Grande, São Paulo, Brazil. Clinical, demographic, and anthropometric data, psychological variables, and physical conditions will be collected through the International Physical Activity Questionnaire (IPAQ) and the risk of falls test. The heart rate R-R intervals will be analyzed using the H10 polar frequency meter and the HRV application, and transferred to the Kúbios software for further analysis.Results: Two hundred and fourteen participants are involved in this study, 181 (84.6%) of whom are female, 137 (64.0%) are white, with a mean age of 70.27 ± 7.07 years, a weight of 68.37 ± 11.15 kg, and a body mass index of 27.04 ± 4.04 kg/m2. Conclusion: A positive correlation is expected through the stratified analysis of frailty indices, risk of falls, and HRV, suggesting that the lower the HRV, the greater the risk of falls and the greater frailty in the elderly. [ABSTRACT FROM AUTHOR]

Introduction/Purpose Obesity increases significantly every year worldwide. Since 1980, the prevalence of individuals with obesity has practically doubled. Obesity plays an important role in the pathophysiology of diseases that arise from a complex interaction of nutritional, genetic, and metabolic factors, characterizing a chronic inflammatory state. This study aimed to verify the systemic inflammatory response through the analysis of IGF-1, IL-23, and resistin levels and the lipid profile in severely obese women undergoing surgery for obesity and weight-related diseases. Materials and Methods This randomized controlled clinical trial includes female patients clinically diagnosed with severe obesity with an indication for bariatric surgery. Results In the initial evaluation, no significant difference was observed between the control (CG) and bariatric surgery (BSG) groups. The weight, BMI, systolic and diastolic blood pressures, total cholesterol, LDL, HDL, total non-HDL cholesterol, and glucose in BSG patients showed a significant change after surgery. Pre- and post-surgery levels of resistin, IGF-1, and IL-23 showed a significant difference in the BSG group, but only IL-23 was changed after 6 months in the CG. Conclusion The results of this study confirmed that weight loss induced by surgery for obesity and weight-related diseases improved the lipid profile and reduced the chronic inflammatory status in women with severe obesity. [ABSTRACT FROM AUTHOR]