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379 results on '"Ricciardiello L."'

1. Evaluation of Artificial Intelligence-Assisted Colonoscopy for Adenoma Detection in Lynch Syndrome: a multicentre randomized controlled trial (Timely study)

Author

Ortiz, O., additional, Rivero-Sánchez, L., additional, Gimeno-Garcia, A., additional, Vicente, J. Lopez, additional, Martínez, R. Jover, additional, Ricciardiello, L., additional, Puig, I., additional, Huneburg, R., additional, Herraiz Bayod, M. T., additional, Abalos, J. Gordillo, additional, Daca-Alvarez, M., additional, Tejpar, S., additional, Bisschops, R., additional, Repici, A., additional, Herrero, J., additional, David, R., additional, Cid, L., additional, Alvarez, V., additional, Romero, C., additional, Huerta, A., additional, Betes, M. T., additional, Riu, F., additional, Carrillo, M., additional, Cavestro, G. M., additional, Balaguer, F., additional, and Pellisé, M., additional

Published
2024
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3. Abdominal desmoid tumours after colectomy and ileorectal anastomosis versus proctocolectomy and ileal pouch-anal anastomosis in familial adenomatous polyposis

Author

Aelvoet, A., additional, Pellisé, M., additional, Miedema, T., additional, Bastiaansen, B.A. J., additional, Van Leerdam, M., additional, Jover, R., additional, Balaguer, F., additional, Kaminski, M. F., additional, Hompes, R., additional, Bossuyt, P.M. M., additional, Ricciardiello, L., additional, Karstensen, J. G., additional, Latchford, A., additional, and Dekker, E., additional

Published
2023
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4. Risk of cancer following colectomy with ileorectal/ileosigmoidal anastomosis and proctocolectomy with ileal pouch-anal anastomosis in familial adenomatous polyposis

Author

Bouchiba, H., additional, Aelvoet, A. S., additional, Pellisé, M., additional, Bastiaansen, B.A. J., additional, Van Leerdam, M. E., additional, Balaguer, F., additional, Kaminski, M. F., additional, Hompes, R., additional, Bossuyt, P.M. M., additional, Ricciardiello, L., additional, Jover, R., additional, Karstensen, J. G., additional, Latchford, A., additional, and Dekker, E., additional

Published
2023
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5. Cold snare polypectomy for duodenal adenomas in familial adenomatous polyposis: a prospective international cohort study

Author

Aelvoet, A., additional, Karstensen, J. G., additional, Bastiaansen, B.A. J., additional, Van Leerdam, M., additional, Balaguer, F., additional, Kaminski, M. F., additional, Hompes, R., additional, Bossuyt, P.M. M., additional, Ricciardiello, L., additional, Latchford, A., additional, Jover, R., additional, Daca-Alvarez, M., additional, Pellisé, M., additional, and Dekker, E., additional

Published
2023
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6. T.02.1 DELPHI INITIATIVE FOR EARLY-ONSET COLORECTAL CANCER (DIRECT): INTERNATIONAL MANAGEMENT GUIDELINES

Author

Cavestro, G.M., primary, Mannucci, A., additional, Balaguer, F., additional, Heather, H., additional, Kupfer, S., additional, Repici, A., additional, Sartore-Bianchi, A., additional, Seppala, T., additional, Valentini, V., additional, Boland, C., additional, Brand, R., additional, Buffart, T., additional, Burke, C., additional, Caccialanza, R., additional, Cannizzaro, R., additional, Cascinu, S., additional, Cercek, A., additional, Crosbie, E., additional, Danese, S., additional, Dekker, E., additional, Daca-Alvarez, M., additional, Deni, F., additional, Latchford, A., additional, Liska, D., additional, Lynch, P., additional, Malesci, A., additional, Mauri, G., additional, Meldolesi, E., additional, Pal, M., additional, Monahan, K., additional, Moslein, G., additional, Murphy, C., additional, Nass, K., additional, Ng, K., additional, Oliani, C., additional, Papaleo, E., additional, Patel, S., additional, Puzzono, M., additional, Remo, A., additional, Ricciardiello, L., additional, Ripamonti, C., additional, Siena, S., additional, Singh, S., additional, Stadler, Z., additional, Stanich, P., additional, Syngal, S., additional, Turi, S., additional, Urso, E., additional, Valle, L., additional, Vanni, V., additional, Vilar, E., additional, Vitellaro, M., additional, You, Y., additional, Yurgelun, M., additional, Zuppardo, R., additional, and Stoffel, E., additional

Published
2023
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7. OC.05.3 EXPRESSION OF TRANSCRIPTION FACTORS OF EPITHELIAL-TOMESENCHYMAL TRANSITION IN PANCREATIC CANCER AND THEIR ASSESSMENT BY LIQUID BIOPSY

Author

Greco, L., primary, Rubbino, F., additional, Paulis, M., additional, Gallioli, A., additional, Finati, E., additional, Di Cristofaro, A., additional, Pistillo, D., additional, Gavazzi, F., additional, Maselli, R., additional, Ferrara, E.C., additional, Gaiani, F., additional, Ricciardiello, L., additional, Repici, A., additional, Zerbi, A., additional, Malesci, A., additional, Falconi, M., additional, and Laghi, L., additional

Published
2023
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8. Delphi initiative for early-onset colorectal cancer (DIRECt). International Management Guidelines

Author

Cavestro Giulia, M, Mannucci, A, Balaguer, F, Hampel, H, Kupfer, SS, Repici, A, Sartore-Bianchi, A, Seppälä Toni, T, Valentini, V, Boland Clement, R, Brand, RE, Buffart, TE, Burke, CA, Caccialanza, R, Cannizzaro, R, Cascinu, S, Cercek, A, Crosbie, EJ, Danese, S, Dekker, E, Daca-Alvarez, M, Deni, F, Dominguez-Valentin, M, Eng, C, Goel, A, Guillem Josè, G, Houwen, B, Kahi, C, Kalady, MF, Kastrinos, F, Kühn, F, Laghi, L, Latchford, A, Liska, D, Lynch, P, Malesci, A, Mauri, G, Meldolesi, E, Møller, P, Monahan, KJ, Moslein, G, Murphy, CC, Nass, K, Ng, K, Oliani, C, Papaleo, E, Patel, SG, Puzzono, M, Remo, A, Ricciardiello, L, Ripamonti Carla, I, Siena, S, Singh, SK, Stadler, ZK, Stanich, PP, Syngal, S, Turi, S, Urso Emanuele, D, Valle, L, Vanni Valeria, S, Vilar, E, Vitellaro, M, You, Y-QN, Yurgelun, MB, Zuppardo Raffaella, A, Stoffel, EM, Associazione Italiana Familiarità Ereditarietà Tumori, Collaborative Group of the Americas on Inherited Gastrointestinal Cancers, European Hereditary Tumor Group, International Society for Gastrointestinal Hereditary Tumours, Tampere University, Clinical Medicine, Department of Gastroenterology, Gastroenterology and Hepatology, CCA - Cancer Treatment and Quality of Life, CCA - Imaging and biomarkers, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, CCA -Cancer Center Amsterdam, and Internal medicine

Subjects
Colorectal Cancer, 50 Years, Clinical, Hepatology, Settore MED/06 - Oncologia Medica, 3122 Cancers, Gastroenterology, Young, Recommendation
Abstract

BACKGROUND & AIMS: Patients with early-onset colorectal cancer (eoCRC) are managed according to guidelines that are not age-specific. A multidisciplinary international group (DIRECt), composed of 69 experts, was convened to develop the first evidence-based consensus recommendations for eoCRC. METHODS: After reviewing the published literature, a Delphi methodology was used to draft and respond to clinically relevant questions. Each statement underwent 3 rounds of voting and reached a consensus level of agreement of ≥80%. RESULTS: The DIRECt group produced 31 statements in 7 areas of interest: diagnosis, risk factors, genetics, pathology-oncology, endoscopy, therapy, and supportive care. There was strong consensus that all individuals younger than 50 should undergo CRC risk stratification and prompt symptom assessment. All newly diagnosed eoCRC patients should receive germline genetic testing, ideally before surgery. On the basis of current evidence, endoscopic, surgical, and oncologic treatment of eoCRC should not differ from later-onset CRC, except for individuals with pathogenic or likely pathogenic germline variants. The evidence on chemotherapy is not sufficient to recommend changes to established therapeutic protocols. Fertility preservation and sexual health are important to address in eoCRC survivors. The DIRECt group highlighted areas with knowledge gaps that should be prioritized in future research efforts, including age at first screening for the general population, use of fecal immunochemical tests, chemotherapy, endoscopic therapy, and post-treatment surveillance for eoCRC patients. CONCLUSIONS: The DIRECt group produced the first consensus recommendations on eoCRC. All statements should be considered together with the accompanying comments and literature reviews. We highlighted areas where research should be prioritized. These guidelines represent a useful tool for clinicians caring for patients with eoCRC. publishedVersion

Published
2022
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10. Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium

Author

Møller, P., Seppälä, T., Dowty, J.G., Haupt, S., Dominguez-Valentin, M., Sunde, L., Bernstein, I., Engel, C., Aretz, S., Nielsen, M., Capella, G., Evans, D.G., Burn, J., Holinski-Feder, E., Bertario, L., Bonanni, B., Lindblom, A., Levi, Z., Macrae, F., Winship, I., Plazzer, J.P., Sijmons, R., Laghi, L., Valle, A.D., Heinimann, K., Half, E., Lopez-Koestner, F., Alvarez-Valenzuela, K., Scott, R.J., Katz, L., Laish, I., Vainer, E., Vaccaro, C.A., Carraro, D.M., Gluck, N., Abu-Freha, N., Stakelum, A., Kennelly, R., Winter, D., Rossi, B.M., Greenblatt, M., Bohorquez, M., Sheth, H., Tibiletti, M.G., Lino-Silva, L.S., Horisberger, K., Portenkirchner, C., Nascimento, I., Rossi, N.T., Silva, L.A. da, Thomas, H, Zaránd, A., Mecklin, J.P., Pylvänäinen, K., Renkonen-Sinisalo, L., Lepisto, A., Peltomäki, P., Therkildsen, C., Lindberg, L.J., Thorlacius-Ussing, O., Doeberitz, M. von Knebel, Loeffler, M., Rahner, N., Steinke-Lange, V., Schmiegel, W., Vangala, D., Perne, C., Hüneburg, R., Vargas, A.F. de, Latchford, A., Gerdes, A.M., Backman, A.S., Guillén-Ponce, C., Snyder, C., Lautrup, C.K., Amor, D., Palmero, E., Stoffel, E., Duijkers, F., Hall, M.J., Hampel, H., Williams, H., Okkels, H., Lubiński, J., Reece, J., Ngeow, J., Guillem, J.G., Arnold, J., Wadt, K., Monahan, K., Senter, L., Rasmussen, L.J., Hest, L.P. van, Ricciardiello, L., Kohonen-Corish, M.R.J., Ligtenberg, M.J.L., Southey, M., Aronson, M., Zahary, M.N., Samadder, N.J., Hoogerbrugge, N., Sampson, J.R., Jenkins, M.A., Møller, P., Seppälä, T., Dowty, J.G., Haupt, S., Dominguez-Valentin, M., Sunde, L., Bernstein, I., Engel, C., Aretz, S., Nielsen, M., Capella, G., Evans, D.G., Burn, J., Holinski-Feder, E., Bertario, L., Bonanni, B., Lindblom, A., Levi, Z., Macrae, F., Winship, I., Plazzer, J.P., Sijmons, R., Laghi, L., Valle, A.D., Heinimann, K., Half, E., Lopez-Koestner, F., Alvarez-Valenzuela, K., Scott, R.J., Katz, L., Laish, I., Vainer, E., Vaccaro, C.A., Carraro, D.M., Gluck, N., Abu-Freha, N., Stakelum, A., Kennelly, R., Winter, D., Rossi, B.M., Greenblatt, M., Bohorquez, M., Sheth, H., Tibiletti, M.G., Lino-Silva, L.S., Horisberger, K., Portenkirchner, C., Nascimento, I., Rossi, N.T., Silva, L.A. da, Thomas, H, Zaránd, A., Mecklin, J.P., Pylvänäinen, K., Renkonen-Sinisalo, L., Lepisto, A., Peltomäki, P., Therkildsen, C., Lindberg, L.J., Thorlacius-Ussing, O., Doeberitz, M. von Knebel, Loeffler, M., Rahner, N., Steinke-Lange, V., Schmiegel, W., Vangala, D., Perne, C., Hüneburg, R., Vargas, A.F. de, Latchford, A., Gerdes, A.M., Backman, A.S., Guillén-Ponce, C., Snyder, C., Lautrup, C.K., Amor, D., Palmero, E., Stoffel, E., Duijkers, F., Hall, M.J., Hampel, H., Williams, H., Okkels, H., Lubiński, J., Reece, J., Ngeow, J., Guillem, J.G., Arnold, J., Wadt, K., Monahan, K., Senter, L., Rasmussen, L.J., Hest, L.P. van, Ricciardiello, L., Kohonen-Corish, M.R.J., Ligtenberg, M.J.L., Southey, M., Aronson, M., Zahary, M.N., Samadder, N.J., Hoogerbrugge, N., Sampson, J.R., and Jenkins, M.A.

Abstract

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Published
2022

11. Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium

Author

Moller, P, Seppala, T, Dowty, JG, Haupt, S, Dominguez-Valentin, M, Sunde, L, Bernstein, I, Engel, C, Aretz, S, Nielsen, M, Capella, G, Evans, DG, Burn, J, Holinski-Feder, E, Bertario, L, Bonanni, B, Lindblom, A, Levi, Z, Macrae, F, Winship, I, Plazzer, J-P, Sijmons, R, Laghi, L, Della Valle, A, Heinimann, K, Half, E, Lopez-Koestner, F, Alvarez-Valenzuela, K, Scott, RJ, Katz, L, Laish, I, Vainer, E, Vaccaro, CA, Carraro, DM, Gluck, N, Abu-Freha, N, Stakelum, A, Kennelly, R, Winter, D, Rossi, BM, Greenblatt, M, Bohorquez, M, Sheth, H, Tibiletti, MG, Lino-Silva, LS, Horisberger, K, Portenkirchner, C, Nascimento, I, Rossi, NT, da Silva, LA, Thomas, H, Zarand, A, Mecklin, J-P, Pylvanainen, K, Renkonen-Sinisalo, L, Lepisto, A, Peltomaki, P, Therkildsen, C, Lindberg, LJ, Thorlacius-Ussing, O, von Knebel Doeberitz, M, Loeffler, M, Rahner, N, Steinke-Lange, V, Schmiegel, W, Vangala, D, Perne, C, Hueneburg, R, de Vargas, AF, Latchford, A, Gerdes, A-M, Backman, A-S, Guillen-Ponce, C, Snyder, C, Lautrup, CK, Amor, D, Palmero, E, Stoffel, E, Duijkers, F, Hall, MJ, Hampel, H, Williams, H, Okkels, H, Lubinski, J, Reece, J, Ngeow, J, Guillem, JG, Arnold, J, Wadt, K, Monahan, K, Senter, L, Rasmussen, LJ, van Hest, LP, Ricciardiello, L, Kohonen-Corish, MRJ, Ligtenberg, MJL, Southey, M, Aronson, M, Zahary, MN, Samadder, NJ, Poplawski, N, Hoogerbrugge, N, Morrison, PJ, James, P, Lee, G, Chen-Shtoyerman, R, Ankathil, R, Pai, R, Ward, R, Parry, S, Debniak, T, John, T, van Overeem Hansen, T, Caldes, T, Yamaguchi, T, Barca-Tierno, V, Garre, P, Cavestro, GM, Weitz, J, Redler, S, Buettner, R, Heuveline, V, Hopper, JL, Win, AK, Lindor, N, Gallinger, S, Le Marchand, L, Newcomb, PA, Figueiredo, J, Buchanan, DD, Thibodeau, SN, ten Broeke, SW, Hovig, E, Nakken, S, Pineda, M, Duenas, N, Brunet, J, Green, K, Lalloo, F, Newton, K, Crosbie, EJ, Mints, M, Tjandra, D, Neffa, F, Esperon, P, Kariv, R, Rosner, G, Pavicic, WH, Kalfayan, P, Torrezan, GT, Bassaneze, T, Martin, C, Moslein, G, Ahadova, A, Kloor, M, Sampson, JR, Jenkins, MA, Moller, P, Seppala, T, Dowty, JG, Haupt, S, Dominguez-Valentin, M, Sunde, L, Bernstein, I, Engel, C, Aretz, S, Nielsen, M, Capella, G, Evans, DG, Burn, J, Holinski-Feder, E, Bertario, L, Bonanni, B, Lindblom, A, Levi, Z, Macrae, F, Winship, I, Plazzer, J-P, Sijmons, R, Laghi, L, Della Valle, A, Heinimann, K, Half, E, Lopez-Koestner, F, Alvarez-Valenzuela, K, Scott, RJ, Katz, L, Laish, I, Vainer, E, Vaccaro, CA, Carraro, DM, Gluck, N, Abu-Freha, N, Stakelum, A, Kennelly, R, Winter, D, Rossi, BM, Greenblatt, M, Bohorquez, M, Sheth, H, Tibiletti, MG, Lino-Silva, LS, Horisberger, K, Portenkirchner, C, Nascimento, I, Rossi, NT, da Silva, LA, Thomas, H, Zarand, A, Mecklin, J-P, Pylvanainen, K, Renkonen-Sinisalo, L, Lepisto, A, Peltomaki, P, Therkildsen, C, Lindberg, LJ, Thorlacius-Ussing, O, von Knebel Doeberitz, M, Loeffler, M, Rahner, N, Steinke-Lange, V, Schmiegel, W, Vangala, D, Perne, C, Hueneburg, R, de Vargas, AF, Latchford, A, Gerdes, A-M, Backman, A-S, Guillen-Ponce, C, Snyder, C, Lautrup, CK, Amor, D, Palmero, E, Stoffel, E, Duijkers, F, Hall, MJ, Hampel, H, Williams, H, Okkels, H, Lubinski, J, Reece, J, Ngeow, J, Guillem, JG, Arnold, J, Wadt, K, Monahan, K, Senter, L, Rasmussen, LJ, van Hest, LP, Ricciardiello, L, Kohonen-Corish, MRJ, Ligtenberg, MJL, Southey, M, Aronson, M, Zahary, MN, Samadder, NJ, Poplawski, N, Hoogerbrugge, N, Morrison, PJ, James, P, Lee, G, Chen-Shtoyerman, R, Ankathil, R, Pai, R, Ward, R, Parry, S, Debniak, T, John, T, van Overeem Hansen, T, Caldes, T, Yamaguchi, T, Barca-Tierno, V, Garre, P, Cavestro, GM, Weitz, J, Redler, S, Buettner, R, Heuveline, V, Hopper, JL, Win, AK, Lindor, N, Gallinger, S, Le Marchand, L, Newcomb, PA, Figueiredo, J, Buchanan, DD, Thibodeau, SN, ten Broeke, SW, Hovig, E, Nakken, S, Pineda, M, Duenas, N, Brunet, J, Green, K, Lalloo, F, Newton, K, Crosbie, EJ, Mints, M, Tjandra, D, Neffa, F, Esperon, P, Kariv, R, Rosner, G, Pavicic, WH, Kalfayan, P, Torrezan, GT, Bassaneze, T, Martin, C, Moslein, G, Ahadova, A, Kloor, M, Sampson, JR, and Jenkins, MA

Abstract

OBJECTIVE: To compare colorectal cancer (CRC) incidences in carriers of pathogenic variants of the MMR genes in the PLSD and IMRC cohorts, of which only the former included mandatory colonoscopy surveillance for all participants. METHODS: CRC incidences were calculated in an intervention group comprising a cohort of confirmed carriers of pathogenic or likely pathogenic variants in mismatch repair genes (path_MMR) followed prospectively by the Prospective Lynch Syndrome Database (PLSD). All had colonoscopy surveillance, with polypectomy when polyps were identified. Comparison was made with a retrospective cohort reported by the International Mismatch Repair Consortium (IMRC). This comprised confirmed and inferred path_MMR carriers who were first- or second-degree relatives of Lynch syndrome probands. RESULTS: In the PLSD, 8,153 subjects had follow-up colonoscopy surveillance for a total of 67,604 years and 578 carriers had CRC diagnosed. Average cumulative incidences of CRC in path_MLH1 carriers at 70 years of age were 52% in males and 41% in females; for path_MSH2 50% and 39%; for path_MSH6 13% and 17% and for path_PMS2 11% and 8%. In contrast, in the IMRC cohort, corresponding cumulative incidences were 40% and 27%; 34% and 23%; 16% and 8% and 7% and 6%. Comparing just the European carriers in the two series gave similar findings. Numbers in the PLSD series did not allow comparisons of carriers from other continents separately. Cumulative incidences at 25 years were < 1% in all retrospective groups. CONCLUSIONS: Prospectively observed CRC incidences (PLSD) in path_MLH1 and path_MSH2 carriers undergoing colonoscopy surveillance and polypectomy were higher than in the retrospective (IMRC) series, and were not reduced in path_MSH6 carriers. These findings were the opposite to those expected. CRC point incidence before 50 years of age was reduced in path_PMS2 carriers subjected to colonoscopy, but not significantly so.

Published
2022

12. T.07.7 INCREASED NUMBER OF COLORECTAL INTERVAL CANCERS IN LYNCH SYNDROME AFTER THE SARS-COV-2 PANDEMIC. A SURVEY-BASED STUDY

Author

Mannucci, A., primary, Puzzono, M., additional, Russo, M., additional, Barchi, A., additional, Zuppardo, R.A., additional, Biamonte, P., additional, Bencardino, S., additional, Leandro, G., additional, Cannizzaro, R., additional, Monica, F., additional, Zagari, R.M., additional, Pasquale, L., additional, Goni, E., additional, Di Leo, M., additional, Ricciardiello, L., additional, and Cavestro, G.M., additional

Published
2022
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13. Digestive diseases. 2022-2025 edition

Author

Abenavoli Monteblanco, L., Aghemo, A. M., Alvaro, D., Annibale, B., Arcidiacono, P. G., Ardizzone, S., Armuzzi, A., Azzaroli, F., Badiali, D., Baiocchi, L., Baldoni, M., Barone, M., Bassotti, G., Bellini, M., Benedetti, A., Bertino, G., Biagi, F., Biancone, L., Brilanti, S., Bugianesi, E., Burra, P., Calabrese, E., Calvaruso, V., Cammarata, G., Caprioli, F. A., Carbone, M., Cardinale, V., Castiglione, F., Catanzaro, R., Cavestro, G. M., Cazzagon, N., Ciancio, A., Consolo, P., Corleto, V. D., Crocè, S. L., Cuomo, R., de Bortoli, N., Del Vecchio Blanco, G., Dell'Era, A., Di Leo, A., Di Marco, V., Dore, P. M., Eusebi, L. H. U., Fabris, L., Facciorusso, A., Fantini, M. C., Federico, A., Fries, W., Fuccio, L., Fusaroli, P., Gabrielli, A., Galli, A., Giannini, E. G., Corradini, S. G., Gravina, A. G., Grassi, L., Guarino, M. P., Invernizzi, P., Iovino, P., Lahner, E., Lampertico, P., Larussa, T., Latella, G., Luzza, F., Maconi, G. E., Marabotto, E., Marchi, S., Marzioni, M., Merli, M., Milani, S., Montagnani, M., Morelli, O., Morisco, F., Nardone, G. A. P., Pallotta, N., Papa, A., Penagini, R., Petta, S., Picarelli, A., Principi, M., Rapaccini, G. L., Pepici, A., Ricci, C., Ricciardiello, L., Ridola, L., Rispo, A., Romano, M., Rumi, M. G., Russo, F. P., Saracco, G. M., Sarnelli, G., Savarino, E. V., Severi, C., Svegliati Baroni, G., Tarocchi, M., Vecchi, M., Viscido, A., Zagari, R. M., and Zingone, F.

Subjects
colon, liver diseases, diseases of the esophagus, stomach, duodenum, liver diseases, diseases of the biliary tract , pancreas, small intestine, colon, duodenum, diseases of the biliary tract, pancreas, small intestine, diseases of the esophagus, stomach
Published
2022

14. JC virus infects the enteric glia of patients with chronic idiopathic intestinal pseudo-obstruction

Author

Selgrad, M., De Giorgio, R., Fini, L., Cogliandro, R.F., Williams, S., Stanghellini, V., Barbara, G., Tonini, M., Corinaldesi, R., Genta, R.M., Domiati-Saad, R., Meyer, R., Goel, A., Boland, C.R., and Ricciardiello, L.

Subjects
Polyoma virus -- Identification and classification, Neuroglia -- Diseases, Intestine, Small -- Diseases, Nervous system, Autonomic -- Diseases, Intestines -- Obstructions, Intestines -- Development and progression, Intestines -- Research, Health
Published
2009

15. How to identify patients who are less likely to have metachronous neoplasms after a colon cancer: A predictive model

Author

Frazzoni, L., Laterza, Lucrezia, Mussetto, A., Zagari, Rocco Maurizio, Trovato, C., De Bellis, Marinella, Paggi, S., Piccirelli, Stefania, Ricciardiello, L., Cesaro, Paola, Spada, Cristiano, Dal Piaz, G., La Marca, M., Fabbian, F., Petrella, Luigi, Smania, V., Marone, P., Tatangelo, F., Bazzoli, F., Radaelli, F., Repici, A., Hassan, Cesare, Scagliarini, M., Fuccio, L., Laterza L., Zagari R. M., De Bellis M., Piccirelli S., Cesaro P., Spada C. (ORCID:0000-0002-5692-0960), Petrella L., Hassan C., Frazzoni, L., Laterza, Lucrezia, Mussetto, A., Zagari, Rocco Maurizio, Trovato, C., De Bellis, Marinella, Paggi, S., Piccirelli, Stefania, Ricciardiello, L., Cesaro, Paola, Spada, Cristiano, Dal Piaz, G., La Marca, M., Fabbian, F., Petrella, Luigi, Smania, V., Marone, P., Tatangelo, F., Bazzoli, F., Radaelli, F., Repici, A., Hassan, Cesare, Scagliarini, M., Fuccio, L., Laterza L., Zagari R. M., De Bellis M., Piccirelli S., Cesaro P., Spada C. (ORCID:0000-0002-5692-0960), Petrella L., and Hassan C.

Abstract

Background âPatients with prior colon cancer have increased risk of metachronous colorectal neoplasms; therefore, endoscopic surveillance is indicated. Current recommendations are not risk-stratified. We investigated predictive factors for colorectal neoplasms to build a model to spare colonoscopies for low-risk patients. Methods â This was a multicenter, retrospective study including patients who underwent surgery for colon cancer in 2001âŠ-âŠ2008 (derivation cohort) and 2009âŠ-âŠ2013 (validation cohort). A predictive model for neoplasm occurrence at second surveillance colonoscopy was developed and validated. Results â 421 and 203 patients were included in derivation and validation cohort, respectively. At second surveillance colonoscopy, 112 (26.6âŠ%) and 55 (27.1âŠ%) patients had metachronous neoplasms in derivation and validation groups; three cancers were detected in the latter. History of left-sided colon cancer (OR 1.64, 95âŠ%CI 1.02âŠ-âŠ2.64), ≥âŠ1 advanced adenoma at index colonoscopy (OR 1.90, 95âŠ%CI 1.05âŠ-âŠ3.43), and ≥âŠ1 adenoma at first surveillance colonoscopy (OR 2.06, 95âŠ%CI 1.29âŠ-âŠ3.27) were independently predictive of metachronous colorectal neoplasms at second surveillance colonoscopy. For patients without such risk factors, diagnostic accuracy parameters were: 89.3âŠ% (95âŠ%CI 82.0âŠ%-94.3âŠ%) and 78.2âŠ% (95âŠ%CI 65.0âŠ%-88.2âŠ%) sensitivity, and 28.5âŠ% (95âŠ%CI 23.5âŠ%-33.9âŠ%) and 33.8âŠ% (95âŠ%CI 26.2âŠ%-42.0âŠ%) specificity in derivation and validation group, respectively. No cancer would be missed. Conclusions â Patients with prior left-sided colon cancer or ≥âŠ1 advanced adenoma at index colonoscopy or ≥âŠ1 adenoma at first surveillance colonoscopy had a significantly higher risk of neoplasms at second surveillance colonoscopy; patients without such factors had much lower risk and could safely skip the second surveillance colonoscopy. A prospective, multicent

Published
2020

16. OC.16.4 HOW TO IDENTIFY PATIENTS LESS LIKELY TO HAVE METACHRONOUS NEOPLASMS AFTER A COLON CANCER: A PREDICTIVE MODEL

Author

Frazzoni, L., primary, Laterza, L., additional, Mussetto, A., additional, Zagari, R.M., additional, Trovato, C., additional, De Bellis, M., additional, Paggi, S., additional, Piccirelli, S., additional, Ricciardiello, L., additional, Cesaro, P., additional, Spada, C., additional, Dal Piaz, G., additional, La Marca, M., additional, Fabbian, F., additional, Petrella, L., additional, Smania, V., additional, Marone, P., additional, Tatangelo, F., additional, Bazzoli, F., additional, Radaelli, F., additional, Repici, A., additional, Hassan, C., additional, Scagliarini, M., additional, and Fuccio, L., additional

Published
2020
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19. Endoscopic management of polyposis syndromes: European Society of Gastrointestinal Endoscopy (ESGE) Guideline

Author

van Leerdam ME, Roos VH, van Hooft JE, Dekker E, Jover R, Kaminski MF, Latchford A, Neumann H, Pellisé M, Saurin JC, Tanis PJ, Wagner A, Balaguer F, and Ricciardiello L

Abstract

ESGE recommends that individuals with hereditary gastrointestinal polyposis syndromes should be surveilled in dedicated units that provide monitoring of compliance and endoscopic performance measures. Strong recommendation, moderate quality of evidence, level of agreement 90 %.ESGE recommends performing esophagogastroduodenoscopy, small-bowel examination, and/or colonoscopy earlier than the planned surveillance procedure if a patient is symptomatic. Strong recommendation, low quality of evidence, level of agreement 100 %.

Published
2019

26. A PREDICTIVE MODEL IDENTIFIES PATIENTS LESS LIKELY TO HAVE ADENOMAS AFTER A COLON CANCER

Author

Frazzoni, L, additional, Scagliarini, M, additional, Laterza, L, additional, Trovato, C, additional, Mussetto, A, additional, De Bellis, M, additional, Paggi, S, additional, Spada, C, additional, Petrella, L, additional, Smania, V, additional, De Bortoli, N, additional, Bazzoli, F, additional, Ricciardiello, L, additional, Radaelli, F, additional, Hassan, C, additional, and Fuccio, L, additional

Published
2019
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27. Membrane human equilibrative nucleoside transporter 1 is associated with a high proliferation rate and worse survival in resected intrahepatic cholangiocarcinoma patients not receiving adjuvant treatments

Author

Tavolari, S., primary, Deserti, M., additional, Vasuri, F., additional, Curti, S., additional, Palloni, A., additional, Pinna, A.D., additional, Cescon, M., additional, Frega, G., additional, De Lorenzo, S., additional, Barbera, M.A., additional, Garajova, I., additional, Ricciardiello, L., additional, Malvi, D., additional, D'Errico-Grigioni, A., additional, Pantaleo, M.A., additional, and Brandi, G., additional

Published
2019
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32. OC.13.4 HIGH FREQUENCY OF SOMATIC APC MOSAICISM IN PATIENTS WITH GENETICALLY UNSOLVED COLORECTAL ADENOMATOUS POLYPOSIS

Author

Piazzi, G., primary, Ciavarella, M., additional, Miccoli, S., additional, Prossomariti, A., additional, Pippucci, T., additional, Bonora, E., additional, Buscherini, F., additional, Palombo, F., additional, Zuntini, R., additional, Balbi, T., additional, Bazzoli, F., additional, Turchetti, D., additional, and Ricciardiello, L., additional

Published
2018
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33. Dietary intake of food bioactives in a cohort of European adults with metabolic syndrome enrolled in the Pathway-27 trial

Author

Sutulic, S., primary, Holmes, M.J., additional, Garelli, S., additional, Herrmann, M., additional, Seifert, S., additional, Amat, J., additional, Blot, A., additional, Marcato, E., additional, Malpuech-Brugère, C., additional, Bub, A., additional, Ricciardiello, L., additional, Bordoni, A., additional, and Orfila, C., additional

Published
2018
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36. Eicosapentaenoic Acid-Free Fatty Acid Strongly Prevents and Suppresses Colonic Tumors in Colitis-Associated Colorectal Cancer

Author

Piazzi G, D'Argenio G, Mazzone G, Prossomariti A, Munarini A, Ceccarelli C, Fazio C, D'Angelo L, Belluzzi A, Chieco P, Hull MA, Romano M, Bazzoli F, Ricciardiello L., Lembo, Vincenzo, VITAGLIONE, PAOLA, FOGLIANO, VINCENZO, American Gastroenterological Association, Piazzi, G, D'Argenio, G, Lembo, Vincenzo, Mazzone, G, Prossomariti, A, Vitaglione, Paola, Fogliano, Vincenzo, Munarini, A, Ceccarelli, C, Fazio, C, D'Angelo, L, Belluzzi, A, Chieco, P, Hull, Ma, Romano, M, Bazzoli, F, and Ricciardiello, L.

Published
2013

39. Assessment of the effects of bioactives on health and wellbeing: clinical protocol design

Author

Malpuech-Brugere, Corinne, Ricciardiello, L., Cano, Noël, Bub, A., Orfila, C., Barth, J., Muller, M., Sébédio, Jean-Louis, Tanai, A., Salvo Burriel, J., Bordoni, A., Unité de Nutrition Humaine (UNH), Institut National de la Recherche Agronomique (INRA)-Université d'Auvergne - Clermont-Ferrand I (UdA)-Clermont Université, Department of Medical and Surgical Sciences, Università degli Studi di Padova = University of Padua (Unipd), Max Rubner-Institut, University of Leeds, Leeds Teaching Hospital (NHS LTHN), AdWare Research Ltd, ADEXGO Ltd, Alma Mater Studiorum Università di Bologna [Bologna] (UNIBO), Grupo Desarrollo, Nutrigenomics Organisation (NuGO). NLD., and Universita degli Studi di Padova

Subjects
anthocyane, syndrome métabolique, [SDV]Life Sciences [q-bio], acide docosahexaénoique, beta glucane, aliment enrichi
Abstract

International audience; PATHWAY-27 will evaluate the effectiveness of docosahexaenoic acid (DHA) alone or in combination with two other bioactives, beta-glucan (BG) and anthocyanins (AC) in reducing some risk factors of Metabolic Syndrome MS. These compounds will be used as ingredients of bioactive-enriched foods (BEF), enriching 3 different widely-consumed food matrices (dairy-, bakery-, egg products) and not as pure compounds. This will allow a better understanding of possible synergisms and bioactive-matrix interactions. BEFs to be tested in clinical studies have been designed, selected and produced by different Pathway’ partners. The aim of this multi-centre, randomized, double- blind, parallel pilot study is to identify the BEF achieving the greatest effect on lipid parameters (reduction in serum triglycerides or increase in HDL-C). The selected BEF will then be tested in a subsequent, larger interventional study. Three different matrices containing DHA, BG and AC given alone or of DHA associated with BG or AC will be tested. 300 men and women at risk for MS will be investigated (either one or two of the following criteria should be met: elevated waist circumference, elevated fasting trigycerides, reduced fasting HDL-C, elevated blood pressure or hypotensive treatment or elevated fasting glucose). MRI, ULE, CRNH will investigate BEFs based on either bakery, dairy or egg products, representing a different food matrix. Each pilot study will be conducted on 100 volunteers for a period of 4 weeks. Participants will be divided in 5 groups receiving BEF enriched with DHA, BG, or AC alone or DHA+BG, or DHA+AC. At baseline and after 4 weeks of intervention, fasting blood samples will be collected for further analysis. Additionally, blood pressure and anthropometric data will be determined. The 3 most effective BEF (one for each matrix) having the most significant impact on end-points selected for this study will be used in a larger randomized, double-blind, placebo-controlled study. The aim will be to understand the mechanisms underlying the effects observed on primary and secondary endpoints related to the consumption of BEF. Omics approaches will be used to examine metabolic changes and potentially identify new markers of effects.

Published
2014

41. JC virus infection in patients with chronic idiopathic intestinal pseudo obstruction

Author

Selgrad M, Fini L, Williams S, Meyer R, Genta R. M, Goel A, Boland C, Ricciardiello L., DE GIORGIO, ROBERTO, COGLIANDRO, ROSANNA FRANCESCA, STANGHELLINI, VINCENZO, BARBARA, GIOVANNI, TONINI, MARCELLO, CORINALDESI, ROBERTO, BRITISH SOCIETY OF GASTROENTEROLOGY, Selgrad M, De Giorgio R, Fini L, Cogliandro R, Stanghellini V, Barbara G, Tonini M, Corinaldesi R, Williams S, Meyer R, Genta R. M, Goel A, Boland C, and Ricciardiello L.

Published
2007

42. Virtual Reality in Mental Health

Author

Riva, G, Alcañiz, M, Bacchetta, M, Baños, R, Buselli, C, Beltrame, F, Botella, C, Castelnuovo, G, Cesa, G, Conti, S, Galimberti, C, Gamberini, L, Gaggioli, A, Klinger, E, Legeron, P, Mantovani, F, Mantovani, G, Molinari, E, Optale, G, Ricciardiello, L, Perpiñá, C, Roy, S, Spagnolli, A, Troiani, R, Weddle, C., ANOLLI, LUIGI MARIA, Riva, G, Alcañiz, M, Anolli, L, Bacchetta, M, Baños, R, Buselli, C, Beltrame, F, Botella, C, Castelnuovo, G, Cesa, G, Conti, S, Galimberti, C, Gamberini, L, Gaggioli, A, Klinger, E, Legeron, P, Mantovani, F, Mantovani, G, Molinari, E, Optale, G, Ricciardiello, L, Perpiñá, C, Roy, S, Spagnolli, A, Troiani, R, and Weddle, C

Subjects
realtà virtuale, salute mentale, comunicazione, internet, virtual reality, mental health, communication, Internet, M-PSI/01 - PSICOLOGIA GENERALE
Published
2004

44. Virtual reality for psycho-neurological assessment and rehabilitation

Author

Riva, G., Alcaniz, M., Anolli, L., Bacchetta, M., Banos, R., Buselli, C., Beltrame, F., Botella, C., Castelnuovo, G., Cesa, G., Conti, S., Galimberti, C., Gamberini, Luciano, Gaggioli, A., Klinger, E., Legeron, P., Mantovani, F., Mantovani, Giuseppe, Molinari, E., Optale, G., Ricciardiello, L., Perpina, C., Roy, S., Spagnolli, Anna, Troiani, R., Weddle, C., Riva, G, Alcañiz, M, Anolli, L, Bacchetta, M, Baños, R, Buselli, C, Beltrame, F, Botella, C, Castelnuovo, G, Cesa, G, Conti, S, Galimberti, C, Gamberini, L, Gaggioli, A, Klinger, E, Legeron, P, Mantovani, F, Mantovani, G, Molinari, E, Optale, G, Ricciardiello, L, Perpiñá, C, Roy, S, Spagnolli, A, Troiani, R, and Weddle, C

Subjects
M-PSI/01 - PSICOLOGIA GENERALE, virtual reality, rehabilitation, telemedicine, realtà virtuale, riabilitazione, telemedicina
Published
2003

50. OC.10.1 EICOSAPENTAENOIC ACID-FREE FATTY ACID PREVENTS AND SUPPRESSES COLONIC TUMOURS IN COLITIS-ASSOCIATED COLORECTAL CANCER

Author

Piazzi, G., primary, D'Argenio, G., additional, Prossomariti, A., additional, Lembo, V., additional, Mazzone, G., additional, Candela, M., additional, Biagi, E., additional, Brigidi, P., additional, Vitaglione, P., additional, Fogliano, V., additional, D'Angelo, L., additional, Fazio, C., additional, Munarini, A., additional, Belluzzi, A., additional, Ceccarelli, C., additional, Chieco, P., additional, Balbi, T., additional, Loadman, P.M., additional, Hull, M.A., additional, Romano, M., additional, Bazzoli, F., additional, and Ricciardiello, L., additional

Published
2014
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