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2. Associations between neuropsychological performance and appetite-regulating hormones in anorexia nervosa and healthy controls: Ghrelin's putative role as a mediator of decision-making

Author

Paslakis, Georgios, Agüera, Zaida, Granero, Roser, Sánchez, Isabel, Riesco, Nadine, Jiménez-Murcia, Susana, Fernández-García, Jose C., Garrido-Sánchez, Lourdes, Tinahones, Francisco J., Casanueva, Felipe F., Baños, Rosa M., Botella, Cristina, Crujeiras, Ana B., Torre, Rafael de la, Fernández-Real, Jose M., Frühbeck, Gema, Ortega, Francisco J., Rodríguez, Amaia, Serra-Majem, Luís, Fitó, Montserrat, Menchón, José M., and Fernández-Aranda, Fernando

Published
2019
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4. Orexin and sleep quality in anorexia nervosa: Clinical relevance and influence on treatment outcome

Author

Sauchelli, Sarah, Jiménez-Murcia, Susana, Sánchez, Isabel, Riesco, Nadine, Custal, Nuria, Fernández-García, Jose C., Garrido-Sánchez, Lourdes, Tinahones, Francisco J., Steiger, Howard, Israel, Mimi, Baños, Rosa M., Botella, Cristina, de la Torre, Rafael, Fernández-Real, Jose M., Ortega, Francisco J., Frühbeck, Gema, Granero, Roser, Tárrega, Salome, Crujeiras, Ana B., Rodríguez, Amaia, Estivill, Xavier, Beckmann, Jacques S., Casanueva, Felipe F., Menchón, Jose M., and Fernández-Aranda, Fernando

Published
2016
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5. Reduced Plasma Orexin-A Concentrations are Associated with Cognitive Deficits in Anorexia Nervosa

Author

Steward, Trevor, Mestre-Bach, Gemma, Granero, Roser, Sánchez, Isabel, Riesco, Nadine, Vintró-Alcaraz, Cristina, Sauchelli, Sarah, Jiménez-Murcia, Susana, Agüera, Zaida, Fernández-García, Jose C., Garrido-Sánchez, Lourdes, Tinahones, Francisco J., Casanueva, Felipe F., Baños, Rosa M., Botella, Cristina, Crujeiras, Ana B., Torre, Rafael de la, Fernández-Real, Jose M., Frühbeck, Gema, Ortega, Francisco J., Rodríguez, Amaia, Menchón, José M., and Fernández-Aranda, Fernando

Published
2019
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8. A Randomised Controlled Comparison of Second‐Level Treatment Approaches for Treatment‐Resistant Adults with Bulimia Nervosa and Binge Eating Disorder: Assessing the Benefits of Virtual Reality Cue Exposure Therapy

Author

Ferrer‐García, Marta, Gutiérrez‐Maldonado, José, Pla‐Sanjuanelo, Joana, Vilalta‐Abella, Ferran, Riva, Giuseppe, Clerici, Massimo, Ribas‐Sabaté, Joan, Andreu‐Gracia, Alexis, Fernandez‐Aranda, Fernando, Forcano, Laura, Riesco, Nadine, Sánchez, Isabel, Escandón‐Nagel, Neli, Gomez‐Tricio, Osane, Tena, Virginia, and Dakanalis, Antonios

Published
2017
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13. Food Addiction in a Spanish Sample of Eating Disorders: DSM-5 Diagnostic Subtype Differentiation and Validation Data

Author

Granero, Roser, Hilker, Ines, Agüera, Zaida, Jiménez-Murcia, Susana, Sauchelli, Sarah, Islam, Mohammed A., Fagundo, Ana B., Sánchez, Isabel, Riesco, Nadine, Dieguez, Carlos, Soriano, José, Salcedo-Sánchez, Cristina, Casanueva, Felipe F., De la Torre, Rafael, Menchón, José M., Gearhardt, Ashley N., and Fernández-Aranda, Fernando

Published
2014
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14. Impulsivity, Emotional Dysregulation and Executive Function Deficits Could Be Associated with Alcohol and Drug Abuse in Eating Disorders

Author

Lozano Madrid, María, Clark Bryan, Danielle, Granero, Roser, Sánchez, Isabel, Riesco, Nadine, Mallorquí-Bagué, Núria, Jiménez-Murcia, Susana, Treasure, Janet, Fernández-Aranda, Fernando, Institute of Psychiatry, Psychology and Neuroscience. Section of Eating Disorders, Lozano Madrid, María, Clark Bryan, Danielle, Granero, Roser, Sánchez, Isabel, Riesco, Nadine, Mallorquí-Bagué, Núria, Jiménez-Murcia, Susana, Treasure, Janet, Fernández-Aranda, Fernando, and Institute of Psychiatry, Psychology and Neuroscience. Section of Eating Disorders

Abstract

Background: Empirical data suggests a high comorbid occurrence of eating disorders (EDs) and substance use disorders (SUDs), as well as neurological and psychological shared characteristics. However, no prior study has identified the neuropsychological features of this subgroup. This study examines the prevalence of alcohol and/or drug abuse (A/DA) symptoms in ED patients. It also compares the clinical features and neuropsychological performance of ED patients with and without A/DA symptoms. Methods: 145 participants (74.5% females) with various forms of diagnosed EDs underwent a comprehensive clinical (TCI-R, SCL-90-R and EDI-2) and neuropsychological assessment (Stroop, WCST and IGT). Results: Approximately 19% of ED patients (across ED subtypes) had A/DA symptoms. Those with A/DA symptoms showed more impulsive behaviours and higher levels of interoceptive awareness (EDI-2), somatisation (SCL-90-R) and novelty seeking (TCI-R). This group also had a lower score in the Stroop-words measure, made more perseverative errors in the WCST and showed a weaker learning trajectory in the IGT. Conclusions: ED patients with A/DA symptoms display a specific phenotype characterised by greater impulsive personality, emotional dysregulation and problems with executive control. Patients with these temperamental traits may be at high risk of developing a SUD.

Published
2020

15. Does ADHD Symptomatology Influence Treatment Outcome and Dropout Risk in Eating Disorders? A longitudinal Study

Author

Testa, Giulia, Baenas, Isabel, Vintró-Alcaraz, Cristina, Granero, Roser, Agüera, Zaida, Sánchez, Isabel, Riesco, Nadine, Jiménez-Murcia, Susana, Fernández-Aranda, Fernando, Testa, Giulia, Baenas, Isabel, Vintró-Alcaraz, Cristina, Granero, Roser, Agüera, Zaida, Sánchez, Isabel, Riesco, Nadine, Jiménez-Murcia, Susana, and Fernández-Aranda, Fernando

Abstract

Attention-deficit/hyperactivity disorder (ADHD) and its symptoms have been shown to be present in patients with eating disorders (EDs) and are associated with increased psychopathology and more dysfunctional personality traits. This study aimed to assess if the presence of ADHD symptoms in patients with EDs affects their short and long-term therapy outcome. A total of 136 consecutively treated ED patients were considered in this study. Baseline pre-treatment evaluation included the Adult ADHD Self-Report Scale (ASRS v1.1) for ADHD symptoms and the assessment of eating symptomatology using the Eating Disorders Inventory (EDI-2). Treatment outcome was evaluated in terms of ED symptoms after cognitive behavioral therapy (CBT) and dropout rate during treatment. Furthermore, we evaluated ED symptoms in treatment completers after a follow-up of 8 years on average. Path analyses assessed the potential mediational role of the EDI-2 total score in the relationship between ADHD and treatment outcome. Results showed that baseline symptoms of ADHD indirectly affected treatment outcome after CBT; the ASRS positive screening was related to higher eating symptomatology (standardized coefficient B = 0.41, p = 0.001, 95% CI: 0.26 to 0.55), and the presence of high ED levels contributed to the increase of dropout (B = 0.15, p = 0.041, 95% CI: 0.03 to 0.33) and a worse treatment outcome (B = 0.18, p = 0.041, 95% CI: 0.01 to 0.35). No direct effect was found between the ASRS positive screening with the risk of dropout (B = −0.08, p = 0.375) and worse treatment outcome (B = −0.07, p = 0.414). These results suggest the relevance of identifying specific treatment approaches for patients with ADHD symptoms and severe eating symptomatology.

Published
2020

16. Clinical and Neurophysiological Correlates of Emotion and Food Craving Regulation in Patients with Anorexia Nervosa

Author

Mallorquí-Bagué, Núria, Lozano-Madrid, María, Testa, Giulia, Vintró Alcaraz, Cristina, Sánchez,Isabel, Riesco, Nadine, Perales, José César, Navas, Juan Francisco, Martínez-Zalacaín, Ignacio, Megías, Alberto, Granero, Roser, Veciana de las Heras, Misericordia, Chami, Rayane, Jiménez-Murcia, Susana, Fernández Formoso, José Antonio, Treasure, Janet, Fernández-Aranda, Fernando, Mallorquí-Bagué, Núria, Lozano-Madrid, María, Testa, Giulia, Vintró Alcaraz, Cristina, Sánchez,Isabel, Riesco, Nadine, Perales, José César, Navas, Juan Francisco, Martínez-Zalacaín, Ignacio, Megías, Alberto, Granero, Roser, Veciana de las Heras, Misericordia, Chami, Rayane, Jiménez-Murcia, Susana, Fernández Formoso, José Antonio, Treasure, Janet, and Fernández-Aranda, Fernando

Abstract

Altres ajuts: Study resulting from the SLT006/17/00246 grant, funded by the Department of Health of the Generalitat de Catalunya by the call "Acció instrumental de programes de recerca orientats en l'àmbit de la recerca i la innovació en salut"., Background: Difficulties in emotion regulation and craving regulation have been linked to eating symptomatology in patients with anorexia nervosa (AN), contributing to the maintenance of their eating disorder. Methods: To investigate clinical and electrophysiological correlates of these processes, 20 patients with AN and 20 healthy controls (HC) completed a computerized task during EEG recording, where they were instructed to down-regulate negative emotions or food craving. Participants also completed self-report measures of emotional regulation and food addiction. The P300 and Late Positive Potential (LPP) ERPs were analysed. Results: LPP amplitudes were significantly smaller during down-regulation of food craving among both groups. Independent of task condition, individuals with AN showed smaller P300 amplitudes compared to HC. Among HC, the self-reported use of re-appraisal strategies positively correlated with LPP amplitudes during emotional regulation task, while suppressive strategies negatively correlated with LPP amplitudes. The AN group, in comparison to the HC group, exhibited greater food addiction, greater use of maladaptive strategies, and emotional dysregulation. Conclusions: Despite the enhanced self-reported psychopathology among AN, both groups indicated neurophysiological evidence of food craving regulation as evidenced by blunted LPP amplitudes in the relevant task condition. Further research is required to delineate the mechanisms associated with reduced overall P300 amplitudes among individuals with AN.

Published
2020

17. Dorsolateral prefrontal cortex and amygdala function during cognitive reappraisal predicts weight restoration and emotion regulation impairment in anorexia nervosa.

Author

Steward, Trevor, Martínez-Zalacaín, Ignacio, Mestre-Bach, Gemma, Sánchez, Isabel, Riesco, Nadine, Jiménez-Murcia, Susana, Fernández-Formoso, Jose A, Veciana de las Heras, Misericordia, Custal, Nuria, Menchón, Jose M, Soriano-Mas, Carles, and Fernandez-Aranda, Fernando

Subjects
OBESITY risk factors, AMYGDALOID body physiology, PREFRONTAL cortex, RESEARCH, SELF-control, COGNITION, WEIGHT gain, TREATMENT effectiveness, RISK assessment, COMPARATIVE studies, AFFECTIVE disorders, EMOTION regulation, ANOREXIA nervosa, STATISTICAL correlation
Abstract

Background: Although deficits in affective processing are a core component of anorexia nervosa (AN), we lack a detailed characterization of the neurobiological underpinnings of emotion regulation impairment in AN. Moreover, it remains unclear whether these neural correlates scale with clinical outcomes. Methods: We investigated the neural correlates of negative emotion regulation in a sample of young women receiving day-hospital treatment for AN (n = 21) and healthy controls (n = 21). We aimed to determine whether aberrant brain activation patterns during emotion regulation predicted weight gain following treatment in AN patients and were linked to AN severity. To achieve this, participants completed a cognitive reappraisal paradigm during functional magnetic resonance imaging. Skin conductance response, as well as subjective distress ratings, were recorded to corroborate task engagement. Results: Compared to controls, patients with AN showed reduced activation in the dorsolateral prefrontal cortex (dlPFC) during cognitive reappraisal [pFWE<0.05, threshold-free cluster enhancement (TFCE) corrected]. Importantly, psycho–physiological interaction analysis revealed reduced functional connectivity between the dlPFC and the amygdala in AN patients during emotion regulation (pFWE<0.05, TFCE corrected), and dlPFC-amygdala uncoupling was associated with emotion regulation deficits (r = −0.511, p = 0.018) and eating disorder severity (r = −0.565, p =.008) in the AN group. Finally, dlPFC activity positively correlated with increases in body mass index (r = 0.471, p = 0.042) and in body fat mass percentage (r = 0.605, p = 0.008) following 12 weeks of treatment. Conclusions: Taken together, our findings indicate that individuals with AN present altered fronto-amygdalar response during cognitive reappraisal and that this response may serve as a predictor of response to treatment and be linked to clinical severity. [ABSTRACT FROM AUTHOR]

Published
2022
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19. A cluster analysis of purging disorder: Validation analyses with eating disorder symptoms, general psychopathology and personality

Author

Krug, Isabel, primary, Granero, Roser, additional, Giles, Sarah, additional, Riesco, Nadine, additional, Agüera, Zaida, additional, Sánchez, Isabel, additional, Jiménez‐Murcia, Susana, additional, Pino‐Gutierrez, Amparo, additional, Codina, Ester, additional, Baenas, Isabel, additional, Valenciano‐Mendoza, Eduardo, additional, Menchón, Jose M., additional, and Fernández‐Aranda, Fernando, additional

Published
2020
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20. COVID ‐19 and eating disorders during confinement: Analysis of factors associated with resilience and aggravation of symptoms

Author

Baenas, Isabel, primary, Caravaca‐Sanz, Elena, additional, Granero, Roser, additional, Sánchez, Isabel, additional, Riesco, Nadine, additional, Testa, Giulia, additional, Vintró‐Alcaraz, Cristina, additional, Treasure, Janet, additional, Jiménez‐Murcia, Susana, additional, and Fernández‐Aranda, Fernando, additional

Published
2020
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21. Dorsolateral prefrontal cortex and amygdala function during cognitive reappraisal predicts weight restoration and emotion regulation impairment in anorexia nervosa

Author

Steward, Trevor, primary, Martínez-Zalacaín, Ignacio, additional, Mestre-Bach, Gemma, additional, Sánchez, Isabel, additional, Riesco, Nadine, additional, Jiménez-Murcia, Susana, additional, Fernández-Formoso, Jose A, additional, Veciana de las Heras, Misericordia, additional, Custal, Nuria, additional, Menchón, Jose M, additional, Soriano-Mas, Carles, additional, and Fernandez-Aranda, Fernando, additional

Published
2020
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24. Clinical and Neurophysiological Correlates of Emotion and Food Craving Regulation in Patients with Anorexia Nervosa

Author

Mallorquí-Bagué, Nuria, primary, Lozano-Madrid, María, additional, Testa, Giulia, additional, Vintró-Alcaraz, Cristina, additional, Sánchez, Isabel, additional, Riesco, Nadine, additional, César Perales, José, additional, Francisco Navas, Juan, additional, Martínez-Zalacaín, Ignacio, additional, Megías, Alberto, additional, Granero, Roser, additional, Veciana De Las Heras, Misericordia, additional, Chami, Rayane, additional, Jiménez-Murcia, Susana, additional, Fernández-Formoso, José Antonio, additional, Treasure, Janet, additional, and Fernández-Aranda, Fernando, additional

Published
2020
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25. Emotional and non‐emotional facets of impulsivity in eating disorders: From anorexia nervosa to bulimic spectrum disorders

Author

Mallorquí‐Bagué, Núria, primary, Testa, Giulia, additional, Lozano‐Madrid, María, additional, Vintró‐Alcaraz, Cristina, additional, Sánchez, Isabel, additional, Riesco, Nadine, additional, Granero, Roser, additional, Perales, Jose C., additional, Navas, Juan F., additional, Megías‐Robles, Alberto, additional, Martínez‐Zalacaín, Ignacio, additional, Veciana de las Heras, Misericordia, additional, Jiménez‐Murcia, Susana, additional, and Fernández‐Aranda, Fernando, additional

Published
2020
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26. Food Addiction in Eating Disorders and Obesity: Analysis of Clusters and Implications for Treatment

Author

Universidade de Santiago de Compostela. Centro de Investigación en Medicina Molecular e Enfermidades Crónicas, Universidade de Santiago de Compostela. Departamento de Fisioloxía, Jiménez Murcia, Susana, Agüera, Zaida, Paslakis, Georgios, Munguia, Lucero, Granero, Roser, Sánchez González, Jéssica, Sánchez, Isabel, Riesco, Nadine, Gearhardt, Ashley N., Diéguez González, Carlos, Fazia, Gilda, Segura García, Cristina, Baenas, Isabel, Menchón, José M., Fernández Aranda, Fernando, Universidade de Santiago de Compostela. Centro de Investigación en Medicina Molecular e Enfermidades Crónicas, Universidade de Santiago de Compostela. Departamento de Fisioloxía, Jiménez Murcia, Susana, Agüera, Zaida, Paslakis, Georgios, Munguia, Lucero, Granero, Roser, Sánchez González, Jéssica, Sánchez, Isabel, Riesco, Nadine, Gearhardt, Ashley N., Diéguez González, Carlos, Fazia, Gilda, Segura García, Cristina, Baenas, Isabel, Menchón, José M., and Fernández Aranda, Fernando

Abstract

Food addiction (FA) has been associated with greater psychopathology in individuals with eating disorders (ED) and obesity (OBE). The current study aims to provide a better phenotypic characterization of the FA construct by conducting a clustering analysis of FA in both conditions (ED and OBE). The total sample was comprised of 234 participants that scored positive on the Yale Food Addiction Scale 2.0. (YFAS-2) (119 bulimia nervosa (BN), 50 binge eating disorder (BED), 49 other specified feeding or eating disorder (OSFED) and 16 OBE). All participants completed a comprehensive battery of questionnaires. Three clusters of FA participants were identified. Cluster 1 (dysfunctional) was characterized by the highest prevalence of OSFED and BN, the highest ED severity and psychopathology, and more dysfunctional personality traits. Cluster 2 (moderate) showed a high prevalence of BN and BED and moderate levels of ED psychopathology. Finally, cluster 3 (adaptive) was characterized by a high prevalence of OBE and BED, low levels of ED psychopathology, and more functional personality traits. In conclusion, this study identified three distinct clusters of ED-OBE patients with FA and provides some insight into a better phenotypic characterization of the FA construct when considering psychopathology, personality and ED pathology. Future studies should address whether these three food addiction categories are indicative of therapy outcome

Published
2019

27. Reduced Plasma Orexin-A Concentrations are Associated with Cognitive Deficits in Anorexia Nervosa

Author

Universidade de Santiago de Compostela. Departamento de Psiquiatría, Radioloxía, Saúde Pública, Enfermaría e Medicina, Steward, Trevor, Mestre Bach, Gemma, Granero, Roser, Sánchez, Isabel, Riesco, Nadine, Vintró Alcaraz, Cristina, Sauchelli, Sarah, Jiménez Murcia, Susana, Agüera, Zaida, Fernández García, Jose C., Garrido Sánchez, Lourdes, Tinahones Madueño, Francisco José, Casanueva Freijo, Felipe, Baños, Rosa M., Botella, Cristina, Crujeiras Martínez, Ana Belén, Torre, Rafael de la, Fernández Real, Jose M., Frühbeck, Gema, Ortega, Francisco J., Rodríguez, Amaia, Menchón, José M., Fernández Aranda, Fernando, Universidade de Santiago de Compostela. Departamento de Psiquiatría, Radioloxía, Saúde Pública, Enfermaría e Medicina, Steward, Trevor, Mestre Bach, Gemma, Granero, Roser, Sánchez, Isabel, Riesco, Nadine, Vintró Alcaraz, Cristina, Sauchelli, Sarah, Jiménez Murcia, Susana, Agüera, Zaida, Fernández García, Jose C., Garrido Sánchez, Lourdes, Tinahones Madueño, Francisco José, Casanueva Freijo, Felipe, Baños, Rosa M., Botella, Cristina, Crujeiras Martínez, Ana Belén, Torre, Rafael de la, Fernández Real, Jose M., Frühbeck, Gema, Ortega, Francisco J., Rodríguez, Amaia, Menchón, José M., and Fernández Aranda, Fernando

Abstract

Orexins/hypocretins are neuropeptides implicated in numerous processes, including food intake and cognition. The role of these peptides in the psychopathology of anorexia nervosa (AN) remains poorly understood. The aim of the current study was to evaluate the associations between plasma orexin-A (OXA) concentrations and neuropsychological functioning in adult women with AN, and a matched control group. Fasting plasma OXA concentrations were taken in 51 females with AN and in 51 matched healthy controls. Set-shifting was assessed using the Wisconsin Card Sorting Test (WCST), whereas decision making was measured using the Iowa Gambling Task (IGT). The AN group exhibited lower plasma OXA levels than the HC group. Lower mean scores were obtained on the IGT in AN patients. WCST perseverative errors were signifcantly higher in the AN group compared to HC. In both the AN and HC group, OXA levels were negatively correlated with WCST non-perseverative errors. Reduced plasma OXA concentrations were found to be associated with set-shifting impairments in AN. Taking into consideration the function of orexins in promoting arousal and cognitive fexibility, future studies should explore whether orexin partly underpins the cognitive impairments found in AN

Published
2019

28. Food Addiction in Eating Disorders and Obesity: Analysis of Clusters and Implications for Treatment

Author

Jiménez-Murcia, Susana, primary, Agüera, Zaida, additional, Paslakis, Georgios, additional, Munguia, Lucero, additional, Granero, Roser, additional, Sánchez-González, Jéssica, additional, Sánchez, Isabel, additional, Riesco, Nadine, additional, Gearhardt, Ashley N, additional, Dieguez, Carlos, additional, Fazia, Gilda, additional, Segura-García, Cristina, additional, Baenas, Isabel, additional, Menchón, José M, additional, and Fernández-Aranda, Fernando, additional

Published
2019
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29. Is food addiction a predictor of treatment outcome among patients with eating disorder?

Author

Romero, Xandra, primary, Agüera, Zaida, additional, Granero, Roser, additional, Sánchez, Isabel, additional, Riesco, Nadine, additional, Jiménez‐Murcia, Susana, additional, Gisbert‐Rodriguez, Montserrat, additional, Sánchez‐González, Jéssica, additional, Casalé, Gemma, additional, Baenas, Isabel, additional, Valenciano‐Mendoza, Eduardo, additional, Menchon, Jose M., additional, Gearhardt, Ashley N., additional, Dieguez, Carlos, additional, and Fernández‐Aranda, Fernando, additional

Published
2019
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30. A Randomized Trial of Virtual Reality-Based Cue Exposure Second-Level Therapy and Cognitive Behavior Second-Level Therapy for Bulimia Nervosa and Binge-Eating Disorder: Outcome at Six-Month Followup

Author

Ferrer-Garcia, Marta, primary, Pla-Sanjuanelo, Joana, additional, Dakanalis, Antonios, additional, Vilalta-Abella, Ferran, additional, Riva, Giuseppe, additional, Fernandez-Aranda, Fernando, additional, Forcano, Laura, additional, Riesco, Nadine, additional, Sánchez, Isabel, additional, Clerici, Massimo, additional, Ribas-Sabaté, Joan, additional, Andreu-Gracia, Alexis, additional, Escandón-Nagel, Neli, additional, Gomez-Tricio, Osane, additional, Tena, Virginia, additional, and Gutiérrez-Maldonado, José, additional

Published
2019
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31. Drive for thinness provides an alternative, more meaningful, severity indicator than the DSM‐5 severity indices for eating disorders.

Author

Krug, Isabel, Binh Dang, An, Granero, Roser, Agüera, Zaida, Sánchez, Isabel, Riesco, Nadine, Jimenez‐Murcia, Susana, Menchón, Jose M., and Fernandez‐Aranda, Fernando

Subjects
PERSONALITY disorders, IMPULSIVE personality, SEVERITY of illness index, LEANNESS, BULIMIA, DESCRIPTIVE statistics, PATHOLOGICAL psychology, CLASSIFICATION of mental disorders, ANOREXIA nervosa, EATING disorders
Abstract

Objective: To assess an alternative trans‐diagnostic indicator for severity based on drive for thinness (DT) for anorexia nervosa (AN), bulimia nervosa (BN), binge‐eating disorder (BED), and other specified feeding or eating disorder (OSFED), and to compare this new approach to the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM‐5) severity categories for EDs. Method: A total of 2,811 ED [428 AN‐restrictive (AN‐R), 313 AN‐binge purging (AN‐BP), 1,340 BN, 329 BED, 154 OSFED/atypical AN (AT), and 223 OSFED/purging disorder (PD)] patients were classified using: (a) The DSM‐5 severity categories and (b) a DT categorisation. These severity classifications were then compared based on ED symptoms, general psychopathology, personality, and impulsive behaviours. Results: For the DSM‐5 categories, most ED patients fell into the 'mild' to 'moderate' categories. Using the DT categories, AN patients were mainly represented in the 'low' DT category, and BN, OSFED/AT, and PD in the 'high' DT category. The clinically significant findings were stronger for the DT than the DSM‐5 severity approach (medium‐to‐large effect sizes). AN‐BP and AN‐R provided the most pronounced effects. Conclusion: Our findings question the clinical value of the DSM‐5 severity categorisation, and provide initial support for an alternative DT severity approach for AN. Highlights : This study assessed an alternative trans‐diagnostic drive for thinness (DT) severity.Category for all eating disorder (ED) sub‐types, and then compared this to the Diagnostic and Statistical Manual of Mental Disorders‐5 (DSM‐5) severity indices for EDs.ED symptoms, general psychopathology, personality, and impulsive behaviours were assessed using both classifications in a total of 2,811 female patients diagnosed with EDs.Clinically significant findings were stronger for the DT than the DSM‐5 severity category (medium‐to‐large effect sizes); there was differentiation of the anorexia nervosa (AN) patients into mainly 'low' DT, and bulimia nervosa (BN) spectrum patients into mainly 'high' DT, vs. most patients were clustered in the 'mild‐to‐moderate' DSM‐5 categories.Our findings provide initial support for an alternative trans‐diagnostic DT severity category that may be more clinically meaningful than the DSM‐5 severity indices for EDs. [ABSTRACT FROM AUTHOR]

Published
2021
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32. Validation of the Spanish Version of the Yale Food Addiction Scale 2.0 (YFAS 2.0) and Clinical Correlates in a Sample of Eating Disorder, Gambling Disorder, and Healthy Control Participants

Author

Granero, Roser, Jiménez-Murcia, Susana, Gerhardt, Ashley N., Agüera, Zaida, Aymamí, Neus, Gómez-Peña, Mónica, Lozano-Madrid, María, Mallorquí-Bagué, Núria, Mestre-Bach, Gemma, Neto-Antao, Maria I., Riesco, Nadine, Sánchez, Isabel, Steward, Trevor, Soriano-Mas, Carles, Vintró-Alcaraz, Cristina, Menchón, José M., Casanueva, Felipe F., Diéguez, Carlos, Fernández-Aranda, Fernando, Granero, Roser, Jiménez-Murcia, Susana, Gerhardt, Ashley N., Agüera, Zaida, Aymamí, Neus, Gómez-Peña, Mónica, Lozano-Madrid, María, Mallorquí-Bagué, Núria, Mestre-Bach, Gemma, Neto-Antao, Maria I., Riesco, Nadine, Sánchez, Isabel, Steward, Trevor, Soriano-Mas, Carles, Vintró-Alcaraz, Cristina, Menchón, José M., Casanueva, Felipe F., Diéguez, Carlos, and Fernández-Aranda, Fernando

Abstract

Aims: Due to the increasing evidence of shared vulnerabilities between addictive behaviors and excessive food intake, the concept of food addiction in specific clinical populations has become a topic of scientific interest. The aim of this study was to validate the Yale Food Addiction Scale (YFAS) 2.0 in a Spanish sample. We also sought to explore food addiction and its clinical correlates in eating disorder (ED) and gambling disorder (GD) patients. Methods: The sample included 301 clinical cases (135 ED and 166 GD), diagnosed according to DSM-5 criteria, and 152 healthy controls (HC) recruited from the general population. Results: Food addiction was more prevalent in patients with ED, than in patients with GD and HC (77.8, 7.8, and 3.3%, respectively). Food addiction severity was associated with higher BMI, psychopathology and specific personality traits, such as higher harm avoidance, and lower self-directedness. The psychometrical properties of the Spanish version of the YFAS 2.0 were excellent with good convergent validity. Moreover, it obtained good accuracy in discriminating between diagnostic subtypes. Conclusions: Our results provide empirical support for the use of the Spanish YFAS 2.0 as a reliable and valid tool to assess food addiction among several clinical populations (namely ED and GD). The prevalence of food addiction is heterogeneous between disorders. Common risk factors such as high levels of psychopathology and low self-directedness appear to be present in individuals with food addiction.

Published
2018

33. Corrigendum : Validation of the Spanish Version of the Yale Food Addiction Scale 2.0 (YFAS 2.0) and Clinical Correlates in a Sample of Eating Disorder, Gambling Disorder and Healthy Control Participants

Author

Granero, Roser, Jiménez-Murcia, Susana, Gearhardt, Ashley N., Agüera, Zaida, Aymamí, Neus, Gómez-Peña, Mónica, Lozano-Madrid, María, Mallorquí-Bagué, Núria, Mestre-Bach, Gemma, Neto-Antao, Maria I., Riesco, Nadine, Sánchez, Isabel, Steward, Trevor, Soriano-Mas, Carles, Vintró-Alcaraz, Cristina, Menchón, José M., Casanueva, Felipe F., Diéguez, Carlos, Fernández-Aranda, Fernando, Granero, Roser, Jiménez-Murcia, Susana, Gearhardt, Ashley N., Agüera, Zaida, Aymamí, Neus, Gómez-Peña, Mónica, Lozano-Madrid, María, Mallorquí-Bagué, Núria, Mestre-Bach, Gemma, Neto-Antao, Maria I., Riesco, Nadine, Sánchez, Isabel, Steward, Trevor, Soriano-Mas, Carles, Vintró-Alcaraz, Cristina, Menchón, José M., Casanueva, Felipe F., Diéguez, Carlos, and Fernández-Aranda, Fernando

Published
2018

34. A Randomised Controlled Comparison of Second-Level Treatment Approaches for Treatment-Resistant Adults with Bulimia Nervosa and Binge Eating Disorder: Assessing the Benefits of Virtual Reality Cue Exposure Therapy

Author

Ferrer-García, Marta, Gutiérrez-Maldonado, José, Pla-Sanjuanelo, Joana, Vilalta-Abella, Ferran, Riva, Giuseppe, Clerici, Massimo, Ribas-Sabaté, Joan, Andreu-Gracia, Alexis, Fernandez-Aranda, Fernando, Forcano, Laura, Riesco, Nadine, Sánchez, Isabel, Escandón-Nagel, Neli, Gomez-Tricio, Osane, Tena, Virginia, Dakanalis, Antonios, Ferrer-García, M, Gutiérrez-Maldonado, J, Pla-Sanjuanelo, J, Vilalta-Abella, F, Riva, G, Clerici, M, Ribas-Sabaté, J, Andreu-Gracia, A, Fernandez-Aranda, F, Forcano, L, Riesco, N, Sánchez, I, Escandón-Nagel, N, Gomez-Tricio, O, Tena, V, and Dakanalis, A

Subjects
Adult, Male, Cognitive Behavioral Therapy, treatment, Virtual Reality Exposure Therapy, bulimia nervosa, Anxiety, Clinical Psychology, binge eating disorders, cue exposure, virtual reality, Binge-Eating Disorder, Bulimia Nervosa, Cognitive Therapy, Craving, Female, Humans, Treatment Outcome, Cues, Psychiatry and Mental Health, binge eating disorder, Settore M-PSI/01 - PSICOLOGIA GENERALE
Abstract

A question that arises from the literature on therapy is whether second-level treatment is effective for patients with recurrent binge eating who fail first-level treatment. It has been shown that subjects who do not stop binge eating after an initial structured cognitive-behavioural treatment (CBT) programme benefit from additional CBT (A-CBT) sessions; however, it has been suggested that these resistant patients would benefit even more from cue exposure therapy (CET) targeting features associated with poor response (e.g. urge to binge in response to a cue and anxiety experienced in the presence of binge-related cues). We assessed the effectiveness of virtual reality-CET as a second-level treatment strategy for 64 patients with bulimia nervosa and binge eating disorder who had been treated with limited results after using a structured CBT programme, in comparison with A-CBT. The significant differences observed between the two groups at post-treatment in dimensional (behavioural and attitudinal features, anxiety, food craving) and categorical (abstinence rates) outcomes highlighted the superiority of virtual reality-CET over A-CBT. Copyright © 2017 John Wiley & Sons, Ltd and Eating Disorders Association.

Published
2017

35. Corrigendum: Validation of the Spanish Version of the Yale Food Addiction Scale 2.0 (YFAS 2.0) and Clinical Correlates in a Sample of Eating Disorder, Gambling Disorder and Healthy Control Participants

Author

Granero, Roser, primary, Jiménez-Murcia, Susana, additional, Gearhardt, Ashley N., additional, Agüera, Zaida, additional, Aymamí, Neus, additional, Gómez-Peña, Mónica, additional, Lozano-Madrid, María, additional, Mallorquí-Bagué, Núria, additional, Mestre-Bach, Gemma, additional, Neto-Antao, Maria I., additional, Riesco, Nadine, additional, Sánchez, Isabel, additional, Steward, Trevor, additional, Soriano-Mas, Carles, additional, Vintró-Alcaraz, Cristina, additional, Menchón, José M., additional, Casanueva, Felipe F., additional, Diéguez, Carlos, additional, and Fernández-Aranda, Fernando, additional

Published
2018
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36. Validation of the Caregiver Skills (CASK) scale in Catalonia: Concordance between caregivers in attitudes and behaviours

Author

Vintró-Alcaraz, Cristina, primary, Mestre-Bach, Gemma, additional, Steward, Trevor, additional, Lozano-Madrid, María, additional, Agüera, Zaida, additional, Jiménez-Murcia, Susana, additional, Pedraza, Anna M., additional, Serrano-Troncoso, Eduardo, additional, Ortiz García, Ana E., additional, Rangil, Teresa, additional, Lorán, Eulalia, additional, Soriano-Pacheco, Jose, additional, Medrano-Puigdollers, Laura, additional, Bujalance-Arguijo, Sara, additional, Badia, Gina, additional, Luque, Maria, additional, Tràfach, Gloria, additional, Gómez, Osane, additional, Peña, Joan, additional, Fabra, Carme, additional, Plana, Maria Teresa, additional, Raspall, Reyes, additional, Sánchez, Isabel, additional, Riesco, Nadine, additional, Granero, Roser, additional, Carretero-Jardí, Cristina, additional, Treasure, Janet, additional, and Fernández-Aranda, Fernando, additional

Published
2018
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37. Validation of the Spanish Version of the Yale Food Addiction Scale 2.0 (YFAS 2.0) and Clinical Correlates in a Sample of Eating Disorder, Gambling Disorder, and Healthy Control Participants

Author

Granero, Roser, primary, Jiménez-Murcia, Susana, additional, Gearhardt, Ashley N., additional, Agüera, Zaida, additional, Aymamí, Neus, additional, Gómez-Peña, Mónica, additional, Lozano-Madrid, María, additional, Mallorquí-Bagué, Núria, additional, Mestre-Bach, Gemma, additional, Neto-Antao, Maria I., additional, Riesco, Nadine, additional, Sánchez, Isabel, additional, Steward, Trevor, additional, Soriano-Mas, Carles, additional, Vintró-Alcaraz, Cristina, additional, Menchón, José M., additional, Casanueva, Felipe F., additional, Diéguez, Carlos, additional, and Fernández-Aranda, Fernando, additional

Published
2018
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38. Caregiver Skills Scale--Spanish and Catalonia Versions

Author

Vintró‐Alcaraz, Cristina, primary, Mestre‐Bach, Gemma, additional, Steward, Trevor, additional, Lozano‐Madrid, María, additional, Agüera, Zaida, additional, Jiménez‐Murcia, Susana, additional, Pedraza, Anna M., additional, Serrano‐Troncoso, Eduardo, additional, Ortiz García, Ana E., additional, Rangil, Teresa, additional, Lorán, Eulalia, additional, Soriano‐Pacheco, Jose, additional, Medrano‐Puigdollers, Laura, additional, Bujalance‐Arguijo, Sara, additional, Badia, Gina, additional, Luque, Maria, additional, Tràfach, Gloria, additional, Gómez, Osane, additional, Peña, Joan, additional, Fabra, Carme, additional, Plana, Maria Teresa, additional, Raspall, Reyes, additional, Sánchez, Isabel, additional, Riesco, Nadine, additional, Granero, Roser, additional, Carretero‐Jardí, Cristina, additional, Treasure, Janet, additional, and Fernández‐Aranda, Fernando, additional

Published
2018
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40. Enduring Changes in Decision Making in Patients with Full Remission from Anorexia Nervosa

Author

Steward, Trevor, Mestre-Bach, Gemma, Agüera, Zaida, Granero, Roser, Martín-Romera, Virginia, Sánchez, Isabel, Riesco, Nadine, Tolosa-Sola, Iris, Fernández-Formoso, José A., Fernández García, José Carlos, Tinahones Madueño, Francisco Javier, Casanueva, Felipe F., Baños, Rosa, Botella, Cristina, Crujeiras, Ana B., Torre, Rafael de la, Fernández-Real, José Manuel, Frühbeck, Gema, Ortega, Francisco J., Rodríguez, Amaia, Jiménez-Murcia, Susana, Menchón, José Manuel, and Fernández Aranda, Fernando

Subjects
Adult, Male, Anorexia Nervosa, Decision Making, Remission Induction, Middle Aged, Models, Psychological, Neuropsychological Tests, anorexia nervosa, decision making, Gambling, Task Performance and Analysis, Humans, Female, cognitive function
Abstract

Background Deficits in neuropsychological functioning have consistently been identified in patients with anorexia nervosa (AN). However, little is known on how decision making in AN patients evolves in response to treatment or whether impairments are reversible. Method AN patients (n = 42) completed the Iowa Gambling Task (IGT) upon admission to a 3-month day-hospital treatment programme and at a 1-year follow-up. Patient IGT performance was compared to age-matched controls (n = 46). Results AN patients displayed poorer performance on the IGT at admission compared to controls (p

Published
2016

41. Emotion Regulation as a Transdiagnostic Feature Among Eating Disorders: Cross-sectional and Longitudinal Approach

Author

Mallorquí-Bagué, Núria, primary, Vintró-Alcaraz, Cristina, additional, Sánchez, Isabel, additional, Riesco, Nadine, additional, Agüera, Zaida, additional, Granero, Roser, additional, Jiménez-Múrcia, Susana, additional, Menchón, José M., additional, Treasure, Janet, additional, and Fernández-Aranda, Fernando, additional

Published
2017
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42. Short-Term Treatment Outcomes and Dropout Risk in Men and Women with Eating Disorders

Author

Agüera, Zaida, primary, Sánchez, Isabel, additional, Granero, Roser, additional, Riesco, Nadine, additional, Steward, Trevor, additional, Martín-Romera, Virginia, additional, Jiménez-Murcia, Susana, additional, Romero, Xandra, additional, Caroleo, Mariarita, additional, Segura-García, Cristina, additional, Menchon, José Manuel, additional, and Fernández-Aranda, Fernando, additional

Published
2017
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43. Non-suicidal Self-injury in Different Eating Disorder Types: Relevance of Personality Traits and Gender

Author

Islam, Mohammed A, Steiger, Howard, Jimenez-Murcia, Susana, Israel, Mimi, Granero, Roser, Agüera, Zaida, Amiel Castro, Rita Tatiana, Sánchez, Isabel, Riesco, Nadine, Menchón, José M, Fernández-Aranda, Fernando, University of Zurich, and Fernández-Aranda, Fernando

Subjects
2738 Psychiatry and Mental Health, Clinical Psychology, Psychiatry and Mental health, 10093 Institute of Psychology, 3203 Clinical Psychology, 150 Psychology
Published
2015

44. Comparación de rasgos de personalidad entre pacientes con trastornos de la conducta alimentaria y sus hermanas sanas

Author

Agüera, Zaida, Jiménez-Murcia, Susana, Granero, Roser, Penelo, Eva, Wagner, Gudrun, Riesco, Nadine, Menchón Magriñá, José Manuel, and Fernández Aranda, Fernando

Subjects
Eating disorders, Obesitat, Obesity, Personalitat, Trastorns de la conducta alimentària, Personality
Abstract

The aims of the study were threefold: 1) analyze differences in symptomatology and general psychopathology among eating disorder (ED) patients and their sisters discordant for eating disorders, 2) identify differential personality vulnerabilities between ED patients and their healthy sisters and 3) identify predictors of developing an eating disorder. The sample consisted of 92 female participants (46 ED patients fulfilling DSM-IV-TR criteria for eating disorders vs 46 healthy sisters). The results showed significant differences in eating symptomatology and general psychopathology. In terms of personality traits, ED patients had higher harm avoidance (p

Published
2011

45. Changes in Body Composition in Anorexia Nervosa: Predictors of Recovery and Treatment Outcome

Author

Agüera, Zaida, primary, Romero, Xandra, additional, Arcelus, Jon, additional, Sánchez, Isabel, additional, Riesco, Nadine, additional, Jiménez-Murcia, Susana, additional, González-Gómez, Jana, additional, Granero, Roser, additional, Custal, Nuria, additional, Montserrat-Gil de Bernabé, Monica, additional, Tárrega, Salomé, additional, Baños, Rosa M., additional, Botella, Cristina, additional, de la Torre, Rafael, additional, Fernández-García, José C., additional, Fernández-Real, José M., additional, Frühbeck, Gema, additional, Gómez-Ambrosi, Javier, additional, Tinahones, Francisco J., additional, Crujeiras, Ana B., additional, Casanueva, Felipe F., additional, Menchón, José M., additional, and Fernández-Aranda, Fernando, additional

Published
2015
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46. Differences and Similarities Between Bulimia Nervosa, Compulsive Buying and Gambling Disorder

Author

Jiménez-Murcia, Susana, primary, Granero, Roser, additional, Moragas, Laura, additional, Steiger, Howard, additional, Israel, Mimi, additional, Aymamí, Neus, additional, Gómez-Peña, Mónica, additional, Sauchelli, Sarah, additional, Agüera, Zaida, additional, Sánchez, Isabel, additional, Riesco, Nadine, additional, Penelo, Eva, additional, Menchón, José M., additional, and Fernández-Aranda, Fernando, additional

Published
2014
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47. Is Non-suicidal Self-injury Related to Impulsivity in Anorexia Nervosa? Results from Self-report and Performance-based Tasks

Author

Claes, Laurence, primary, Fagundo, Ana B., additional, Jiménez-Murcia, Susana, additional, Agüera, Zaida, additional, Giner-Bartolome, Cristina, additional, Granero, Roser, additional, Sánchez, Isabel, additional, Riesco, Nadine, additional, Menchón, Jose Manuel, additional, Tarrega, Salomé, additional, and Fernandez-Aranda, Fernando, additional

Published
2014
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48. Explicit and Implicit Emotional Expression in Bulimia Nervosa in the Acute State and after Recovery

Author

Tárrega, Salomé, primary, Fagundo, Ana B., additional, Jiménez-Murcia, Susana, additional, Granero, Roser, additional, Giner-Bartolomé, Cristina, additional, Forcano, Laura, additional, Sánchez, Isabel, additional, Santamaría, Juan José, additional, Ben-Moussa, Maher, additional, Magnenat-Thalmann, Nadia, additional, Konstantas, Dimitri, additional, Lucas, Mikkel, additional, Nielsen, Jeppe, additional, Bults, Richard G. A., additional, Lam, Tony, additional, Kostoulas, Theodoros, additional, Fakotakis, Nikos, additional, Riesco, Nadine, additional, Wolz, Ines, additional, Comín-Colet, Josep, additional, Cardi, Valentina, additional, Treasure, Janet, additional, Fernández-Formoso, José Antonio, additional, Menchón, José Manuel, additional, and Fernández-Aranda, Fernando, additional

Published
2014
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49. Treatment outcome of patients with comorbid type 1 diabetes and eating disorders

Author

Custal, Nuria, primary, Arcelus, Jon, additional, Agüera, Zaida, additional, Bove, Francesca I, additional, Wales, Jackie, additional, Granero, Roser, additional, Jiménez-Murcia, Susana, additional, Sánchez, Isabel, additional, Riesco, Nadine, additional, Alonso, Pino, additional, Crespo, José M, additional, Virgili, Nuria, additional, Menchón, Jose M, additional, and Fernandez-Aranda, Fernando, additional

Published
2014
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50. Yale Food Addiction Scale--Spanish Version

Author

Granero, Roser, primary, Hilker, Ines, additional, Agüera, Zaida, additional, Jiménez-Murcia, Susana, additional, Sauchelli, Sarah, additional, Islam, Mohammed A., additional, Fagundo, Ana B., additional, Sánchez, Isabel, additional, Riesco, Nadine, additional, Dieguez, Carlos, additional, Soriano, José, additional, Salcedo-Sánchez, Cristina, additional, Casanueva, Felipe F., additional, De la Torre, Rafael, additional, Menchón, José M., additional, Gearhardt, Ashley N., additional, and Fernández-Aranda, Fernando, additional

Published
2014
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