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2. sj-doc-1-acr-10.1177_02841851211055163 - Supplemental material for Chest radiography findings of COVID-19 pneumonia: a specific pattern for a confident differential diagnosis

Author

Landini, Nicholas, Colzani, Giulia, Ciet, Pierluigi, Tessarin, Giovanni, Dorigo, Alberto, Bertana, Luca, Felice, Carla, Scaldaferri, Luca, Orlandi, Martina, Nardi, Cosimo, Romagnoli, Micaela, Saba, Luca, Rigoli, Roberto, and Morana, Giovanni

Subjects
110320 Radiology and Organ Imaging, FOS: Clinical medicine
Abstract

Supplemental material, sj-doc-1-acr-10.1177_02841851211055163 for Chest radiography findings of COVID-19 pneumonia: a specific pattern for a confident differential diagnosis by Nicholas Landini, Giulia Colzani, Pierluigi Ciet, Giovanni Tessarin, Alberto Dorigo, Luca Bertana, Carla Felice, Luca Scaldaferri, Martina Orlandi, Cosimo Nardi, Micaela Romagnoli, Luca Saba, Roberto Rigoli and Giovanni Morana in Acta Radiologica

Published
2023
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6. Chest radiography findings of COVID-19 pneumonia: a specific pattern for a confident differential diagnosis

Author

Landini, Nicholas, primary, Colzani, Giulia, additional, Ciet, Pierluigi, additional, Tessarin, Giovanni, additional, Dorigo, Alberto, additional, Bertana, Luca, additional, Felice, Carla, additional, Scaldaferri, Luca, additional, Orlandi, Martina, additional, Nardi, Cosimo, additional, Romagnoli, Micaela, additional, Saba, Luca, additional, Rigoli, Roberto, additional, and Morana, Giovanni, additional

Published
2021
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10. Chest radiography findings of COVID-19 pneumonia: a specific pattern for a confident differential diagnosis.

Author

Landini, Nicholas, Colzani, Giulia, Ciet, Pierluigi, Tessarin, Giovanni, Dorigo, Alberto, Bertana, Luca, Felice, Carla, Scaldaferri, Luca, Orlandi, Martina, Nardi, Cosimo, Romagnoli, Micaela, Saba, Luca, Rigoli, Roberto, and Morana, Giovanni

Abstract

Background: Chest radiography (CR) patterns for the diagnosis of COVID-19 have been established. However, they were not ideated comparing CR features with those of other pulmonary diseases. Purpose: To create the most accurate COVID-19 pneumonia pattern comparing CR findings of COVID-19 and non-COVID-19 pulmonary diseases and to test the model against the British Society of Thoracic Imaging (BSTI) criteria. Material and Methods: CR of COVID-19 and non-COVID-19 pulmonary diseases, admitted to the emergency department, were evaluated. Assessed features were interstitial opacities, ground glass opacities, and/or consolidations and the predominant lung alteration. We also assessed uni-/bilaterality, location (upper/middle/lower), and distribution (peripheral/perihilar), as well as pleural effusion and perihilar vessels blurring. A binary logistic regression was adopted to obtain the most accurate CR COVID-19 pattern, and sensitivity and specificity were computed. The newly defined pattern was compared to BSTI criteria. Results: CR of 274 patients were evaluated (146 COVID-19, 128 non-COVID-19). The most accurate COVID-19 pneumonia pattern consisted of four features: bilateral alterations (Expß=2.8, P =0.002), peripheral distribution of the predominant (Expß=2.3, P =0.013), no pleural effusion (Expß=0.4, P =0.009), and perihilar vessels' contour not blurred (Expß=0.3, P =0.002). The pattern showed 49% sensitivity, 81% specificity, and 64% accuracy, while BSTI criteria showed 51%, 77%, and 63%, respectively. Conclusion: Bilaterality, peripheral distribution of the predominant lung alteration, no pleural effusion, and perihilar vessels contour not blurred determine the most accurate COVID-19 pneumonia pattern. Lower field involvement, proposed by BSTI criteria, was not a distinctive finding. The BSTI criteria has lower specificity. [ABSTRACT FROM AUTHOR]

Published
2022
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12. Community Use of Face Masks against the Spread of COVID-19

Author

Bubbico, Luciano, primary, Mastrangelo, Giuseppe, additional, Larese-Filon, Francesca, additional, Basso, Paolo, additional, Rigoli, Roberto, additional, Maurelli, Martina, additional, Ferlito, Salvatore, additional, Capelli, Marco, additional, Gisabella, Claudio, additional, Javanbakht, Mohammad, additional, Bellizzi, Saverio, additional, and Cegolon, Luca, additional

Published
2021
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13. High prevalence of long-term psychophysical olfactory dysfunction in patients with COVID-19

Author

Boscolo-Rizzo, Paolo, primary, Menegaldo, Anna, additional, Fabbris, Cristoforo, additional, Spinato, Giacomo, additional, Borsetto, Daniele, additional, Vaira, Luigi Angelo, additional, Calvanese, Leonardo, additional, Pettorelli, Andrea, additional, Sonego, Massimo, additional, Frezza, Daniele, additional, Bertolin, Andy, additional, Cestaro, Walter, additional, Rigoli, Roberto, additional, Tirelli, Giancarlo, additional, Mosto, Maria Cristina Da, additional, Menini, Anna, additional, Polesel, Jerry, additional, and Hopkins, Claire, additional

Published
2021
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14. Six-Month Psychophysical Evaluation of Olfactory Dysfunction in Patients with COVID-19

Author

Boscolo-Rizzo, Paolo, primary, Menegaldo, Anna, additional, Fabbris, Cristoforo, additional, Spinato, Giacomo, additional, Borsetto, Daniele, additional, Vaira, Luigi Angelo, additional, Calvanese, Leonardo, additional, Pettorelli, Andrea, additional, Sonego, Massimo, additional, Frezza, Daniele, additional, Bertolin, Andy, additional, Cestaro, Walter, additional, Rigoli, Roberto, additional, D’Alessandro, Andrea, additional, Tirelli, Giancarlo, additional, Da Mosto, Maria Cristina, additional, Menini, Anna, additional, Polesel, Jerry, additional, and Hopkins, Claire, additional

Published
2021
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16. Comparative activity of carbapenem testing: the COMPACT study

Author

Nordmann, Patrice, Picazo, Juan J., Mutters, Reinier, Korten, Volkan, Quintana, Alvaro, Laeuffer, Joerg M., Seak, Joyce Chen Hian, Flamm, Robert K., Morrissey, Ian, Azadian, Berge, El-Bouri, Khalid, Jones, Graeme, Masterton, Bob, Morgan, Marina, Oppenheim, Beryl, Waghorn, David, Smyth, Edmond, Abele-Horn, Marianne, Jacobs, Enno, Mai, Uwe, Mutters, Reinier, Pfister, Wolfgang, Schoerner, Christoph, Seifert, Harald, Bebear, Cécile, Bingen, Edouard, Bonnet, Richard, Jehl, François, Levy, Pierre-Yves, Nordmann, Patrice, Delvallez, Micheline Roussel, Paniara, Olga, Papaparaskevas, Joseph, Piotr, Heczko, Kolář, Milan, Žemličková, Helena, Hanzen, Juraj, Kotulová, Daniela, Campa, Mario, Fadda, Giovanni, Fortina, Giacomo, Gesu, Giovanni, Manso, Esther, Milano, Fulvia, Nicoletti, Giuseppe, Pucillo, Leopoldo, Rigoli, Roberto, Rossolini, Gianmaria, Sambri, Vittorio, Sarti, Mario, Akaln, Halis, Snrtaş, Melda, Akova, Murat, Hasçelik, Gülşen, Arman, Dilek, Dizbay, Murat, Aygen, Bilgehan, Sümerkan, Bülent, Dokuzoğuz, Başak, Esener, Harika, Eraksoy, Haluk, Başaran, Seniha, Köksal, İftihar, Bayramoğlu, Gülçin, Korten, Volkan, Söyletir, Güner, Ulusoy, Sercan, Tünger, Alper, Yalçn, Ata Nevzat, Öğünç, Dilara, Bou, Germán, Bouza, Emilio, Canton, Rafael, Coll, Pere, García-Rodriguez, José Ángel, Gimeno, Concepción, Gobernado, Miguel, Bertomeu, Frederic Gomez, Gómez-Garcés, José Luis, Marco, Francesc, Martínez-Martínez, Luis, Pascual, Alvaro, Pérez, José Luis, Picazo, Juan, Prats, Guillem, Linares, Maria Saumoy, Ghaly, Farid, Cristino, Melo, Diogo, Jose, Ramos, Helena, Balode, Arta, Jürna-Ellam, Marika, and Koslov, Roman

Published
2011
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18. Evolution of Altered Sense of Smell or Taste in Patients With Mildly Symptomatic COVID-19

Author

Boscolo-Rizzo, Paolo, primary, Borsetto, Daniele, additional, Fabbris, Cristoforo, additional, Spinato, Giacomo, additional, Frezza, Daniele, additional, Menegaldo, Anna, additional, Mularoni, Francesca, additional, Gaudioso, Piergiorgio, additional, Cazzador, Diego, additional, Marciani, Silvia, additional, Frasconi, Samuele, additional, Ferraro, Maria, additional, Berro, Cecilia, additional, Varago, Chiara, additional, Nicolai, Piero, additional, Tirelli, Giancarlo, additional, Da Mosto, Maria Cristina, additional, Obholzer, Rupert, additional, Rigoli, Roberto, additional, Polesel, Jerry, additional, and Hopkins, Claire, additional

Published
2020
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19. Use of RAAS Inhibitors and Risk of Clinical Deterioration in COVID-19: Results From an Italian Cohort of 133 Hypertensives

Author

Felice, Carla, primary, Nardin, Chiara, additional, Di Tanna, Gian Luca, additional, Grossi, Ugo, additional, Bernardi, Enrico, additional, Scaldaferri, Luca, additional, Romagnoli, Micaela, additional, Tonon, Luca, additional, Cavasin, Paola, additional, Novello, Simone, additional, Scarpa, Riccardo, additional, Farnia, Antonio, additional, De Menis, Ernesto, additional, Rigoli, Roberto, additional, Cinetto, Francesco, additional, Pauletto, Paolo, additional, Agostini, Carlo, additional, and Rattazzi, Marcello, additional

Published
2020
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20. New onset of loss of smell or taste in household contacts of home-isolated SARS-CoV-2 positive subjects

Author

Boscolo-Rizzo, Paolo, primary, Borsetto, Daniele, additional, Spinato, Giacomo, additional, Fabbris, Cristoforo, additional, Menegaldo, Anna, additional, Gaudioso, Piergiorgio, additional, Nicolai, Piero, additional, Tirelli, Giancarlo, additional, Mosto, Maria Cristina Da, additional, Rigoli, Roberto, additional, Polesel, Jerry, additional, and Hopkins, Claire, additional

Published
2020
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21. Surveillance for West Nile, dengue, and chikungunya virus infections, Veneto Region, Italy, 2010

Author

Gobbi, Federico, Barzon, Luisa, Capelli, Gioia, Angheben, Andrea, Pacenti, Monia, Napoletano, Giuseppina, Piovesan, Cinzia, Montarsi, Fabrizio, Martini, Simone, Rigoli, Roberto, Cattelan, Anna M., Rinaldi, Roberto, Conforto, Mario, Russo, Francesca, Palu, Giorgio, and Bisoffi, Zeno

Subjects
Diseases, International economic relations, Health aspects, West Nile fever -- Health aspects, Dengue fever -- Health aspects, Dengue -- Health aspects
Abstract

In 2010, a special surveillance for West Nile virus (WNV), dengue virus (DENV), and chikungunya virus (CHIKV) was initiated in the Veneto Region of northeastern Italy. The surveillance had 2 [...]

Published
2012
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22. Incidence, Risk Factors and Outcome of Pre-engraftment Gram-Negative Bacteremia After Allogeneic and Autologous Hematopoietic Stem Cell Transplantation: An Italian Prospective Multicenter Survey

Author

Girmenia, Corrado, Bertaina, Alice, Piciocchi, Alfonso, Perruccio, Katia, Algarotti, Alessandra, Busca, Alessandro, Cattaneo, Chiara, Raiola, Anna Maria, Guidi, Stefano, Iori, Anna Paola, Candoni, Anna, Irrera, Giuseppe, Milone, Giuseppe, Marcacci, Giampaolo, Scimè, Rosanna, Musso, Maurizio, Cudillo, Laura, Sica, Simona, Castagna, Luca, Corradini, Paolo, Marchesi, Francesco, Pastore, Domenico, Alessandrino, Emilio Paolo, Annaloro, Claudio, Ciceri, Fabio, Santarone, Stella, Nassi, Luca, Farina, Claudio, Viscoli, Claudio, Rossolini, Gian Maria, Bonifazi, Francesca, Rambaldi, Alessandro, Capria, Saveria, Bertaina, A., Mastronuzzi, Angela, Pagliara, Daria, Bernaschi, Paola, Amico, Lucia, Carotti, Alessandra, Mencacci, Antonella, Busca, A., Bruno, Benedetto, Costa, Cristina, Passi, Angela, Ravizzola, Giuseppe, Angelucci, Emanuele, Marchese, Anna, Pecile, Patrizia, Candoni, A., Ventura, Giovanna, Fanin, Renato, Scarparo, Claudio, Barbaro, Angelo, Milone, G., Leotta, Salvatore, Marchese, Anna Elisa, Marcacci, G., Becchimanzi, Cristina, Donnarumma, Daniela, Tringali, Stefania, Baldi, Maria Teresa, Scalone, Renato, Cudillo, L., Picardi, Alessandra, Arcese, William, Fontana, Carla, Sica, S., Giammarco, Sabrina, Spanu, Teresa, Castagna, L., Crocchiolo, Roberto, Casari, Erminia, Mussetti, Alberto, Conte, Eutilia, Ensoli, Fabrizio, Miragliotta, Giuseppe, Marone, Piero, Arghittu, Milena, Greco, Raffaella, Forcina, Alessandra, Chichero, Paola, Santarone, S., Di Bartolomeo, Paolo, Fazii, Paolo, Kroumova, Vesselina, Decembrino, Nunzia, Zecca, Marco, Pisapia, Giovanni, Palazzo, Giulia, Lanino, Edoardo, Faraci, Maura, Castagnola, Elio, Bandettini, Roberto, Pastano, Rocco, Sammassimo, Simona, Passerini, Rita, Stefani, Piero Maria, Gherlinzoni, Filippo, Rigoli, Roberto, Prezioso, Lucia, Cambò, Benedetta, Calderaro, Adriana, Carella, Angelo Michele, Cascavilla, Nicola, Labonia, Maria Teresa, Celeghini, Ivana, Mordini, Nicola, Piana, Federica, Vacca, Adriana, Sanna, Marco, Podda, Giovanni, Corsetti, Maria Teresa, Rocchetti, Andrea, Cilloni, Daniela, De Gobbi, Marco, Bianco, Ornella, Fagioli, Franca, Carraro, Francesca, De Intinis, Gianfranco, Severino, Alessandro, Proia, Anna, Parisi, Gabriella, Vallisa, Daniele, Confalonieri, Massimo, Russo, Domenico, Malagola, Michele, Galieni, Piero, Falcioni, Sadia, Travaglini, Valeria, Raimondi, Roberto, Borghero, Carlo, Pavan, Giacomina, Prete, Arcangelo, Belotti, Tamara, Ambretti, Simone, Imola, Manuela, Mianulli, Anna Maria, Pedna, Maria Federica, Cesaro, Simone, Lo Cascio, Giuliana, Ferrari, Antonella, Piedimonte, Monica, Santino, Iolanda, Calandrelli, Monica, Olivieri, Attilio, Orecchioni, Francesca, Mirabile, Milena, Centurioni, Riccardo, Gironacci, Luciana, Caravelli, Daniela, Gallo, Susanna, De Filippi, Marco, Cupelli, Luca, Dentamaro, Teresa, Falco, Silvana, Eugenio, Ospedale S, Marotta, Serena, Risitano, Antonio, Lula, Dora, Musto, Pellegrino, Pietrantuono, Giuseppe, Traficante, Antonio, Cerchiara, Elisabetta, Tirindelli, Maria Cristina, Dicuonzo, Giordano, Chierichini, Anna, Anaclerico, Barbara, Placanica, Paola, Girmenia, C, Bertaina, A, Piciocchi, A, Perruccio, K, Algarotti, A, Busca, A, Cattaneo, C, Raiola, Am, Guidi, S, Iori, Ap, Candoni, A, Irrera, G, Milone, G, Marcacci, G, Scimè, R, Musso, M, Cudillo, L, Sica, S, Castagna, L, Corradini, P, Marchesi, F, Pastore, D, Alessandrino, Ep, Annaloro, C, Ciceri, F, Santarone, S, Nassi, L, Farina, C, Viscoli, C, Rossolini, Gm, Bonifazi, F, Rambaldi, A, for the Gruppo Italiano Trapianto di Midollo Osseo, (GITMO), Associazione Microbiologi Clinici Italiani, (AMCLI), Girmenia, Corrado, Bertaina, Alice, Piciocchi, Alfonso, Perruccio, Katia, Algarotti, Alessandra, Busca, Alessandro, Cattaneo, Chiara, Raiola, Anna Maria, Guidi, Stefano, Iori, Anna Paola, Candoni, Anna, Irrera, Giuseppe, Milone, G., Marcacci, Giampaolo, Scimè, Rosanna, Musso, Maurizio, Cudillo, Laura, Sica, Simona, Castagna, Luca, Corradini, Paolo, Marchesi, Francesco, Pastore, Domenico, Alessandrino, Emilio Paolo, Annaloro, Claudio, Ciceri, Fabio, Santarone, Stella, Nassi, Luca, Farina, Claudio, Viscoli, Claudio, Rossolini, Gian Maria, Bonifazi, Francesca, Rambaldi, Alessandro, Capria, Saveria, Bertaina, A., Mastronuzzi, Angela, Pagliara, Daria, Bernaschi, Paola, Amico, Lucia, Carotti, Alessandra, Mencacci, Antonella, Busca, A., Bruno, Benedetto, Costa, Cristina, Passi, Angela, Ravizzola, Giuseppe, Angelucci, Emanuele, Marchese, Anna, Pecile, Patrizia, Candoni, A., Ventura, Giovanna, Fanin, Renato, Scarparo, Claudio, Barbaro, Angelo, Leotta, Salvatore, Marchese, Anna Elisa, Marcacci, G., Becchimanzi, Cristina, Donnarumma, Daniela, Tringali, Stefania, Baldi, Maria Teresa, Scalone, Renato, Cudillo, L., Picardi, Alessandra, Arcese, William, Fontana, Carla, Sica, S., Giammarco, Sabrina, Spanu, Teresa, Castagna, L., Crocchiolo, Roberto, Casari, Erminia, Mussetti, Alberto, Conte, Eutilia, Ensoli, Fabrizio, Miragliotta, Giuseppe, Marone, Piero, Arghittu, Milena, Greco, Raffaella, Forcina, Alessandra, Chichero, Paola, Santarone, S., Di Bartolomeo, Paolo, Fazii, Paolo, Kroumova, Vesselina, Decembrino, Nunzia, Zecca, Marco, Pisapia, Giovanni, Palazzo, Giulia, Lanino, Edoardo, Faraci, Maura, Castagnola, Elio, Bandettini, Roberto, Pastano, Rocco, Sammassimo, Simona, Passerini, Rita, Stefani, Piero Maria, Gherlinzoni, Filippo, Rigoli, Roberto, Prezioso, Lucia, Cambò, Benedetta, Calderaro, Adriana, Carella, Angelo Michele, Cascavilla, Nicola, Labonia, Maria Teresa, Celeghini, Ivana, Mordini, Nicola, Piana, Federica, Vacca, Adriana, Sanna, Marco, Podda, Giovanni, Corsetti, Maria Teresa, Rocchetti, Andrea, Cilloni, Daniela, De Gobbi, Marco, Bianco, Ornella, Fagioli, Franca, Carraro, Francesca, De Intinis, Gianfranco, Severino, Alessandro, Proia, Anna, Parisi, Gabriella, Vallisa, Daniele, Confalonieri, Massimo, Russo, Domenico, Malagola, Michele, Galieni, Piero, Falcioni, Sadia, Travaglini, Valeria, Raimondi, Roberto, Borghero, Carlo, Pavan, Giacomina, Prete, Arcangelo, Belotti, Tamara, Ambretti, Simone, Imola, Manuela, Mianulli, Anna Maria, Pedna, Maria Federica, Cesaro, Simone, Lo Cascio, Giuliana, Ferrari, Antonella, Piedimonte, Monica, Santino, Iolanda, Calandrelli, Monica, Olivieri, Attilio, Orecchioni, Francesca, Mirabile, Milena, Centurioni, Riccardo, Gironacci, Luciana, Caravelli, Daniela, Gallo, Susanna, De Filippi, Marco, Cupelli, Luca, Dentamaro, Teresa, Falco, Silvana, Eugenio, Ospedale S, Marotta, Serena, Risitano, Antonio, Lula, Dora, Musto, Pellegrino, Pietrantuono, Giuseppe, Traficante, Antonio, Cerchiara, Elisabetta, Tirindelli, Maria Cristina, Dicuonzo, Giordano, Chierichini, Anna, Anaclerico, Barbara, and Placanica, Paola

Subjects
0301 basic medicine, Male, Transplantation Conditioning, Drug Resistance, Bacteremia, 0302 clinical medicine, epidemiology, Gram negative bacteremia, multidrug resistance, stem cell transplant, survival, Risk Factors, Drug Resistance, Multiple, Bacterial, Epidemiology, Medicine, Age Factor, Prospective Studies, Prospective cohort study, Child, Transplantation, Homologou, education.field_of_study, Incidence (epidemiology), Incidence, Bacterial, Age Factors, Hematopoietic Stem Cell Transplantation, Middle Aged, Transplantation, Autologou, surgical procedures, operative, Infectious Diseases, Italy, Child, Preschool, Female, medicine.symptom, Multiple, Autologous, Human, Homologous, Microbiology (medical), Adult, medicine.medical_specialty, Adolescent, 030106 microbiology, Population, Transplantation, Autologous, 03 medical and health sciences, Young Adult, Internal medicine, Gram-Negative Bacteria, Gram-Negative Bacterial Infection, Escherichia coli, Humans, Transplantation, Homologous, Preschool, education, Aged, Gram-Negative Bacterial Infections, Infant, Transplantation, business.industry, Risk Factor, medicine.disease, Prospective Studie, Carriage, Otitis, business, Settore MED/15 - Malattie del Sangue, 030215 immunology
Abstract

Background Gram-negative bacteremia (GNB) is a major cause of illness and death after hematopoietic stem cell transplantation (HSCT), and updated epidemiological investigation is advisable. Methods We prospectively evaluated the epidemiology of pre-engraftment GNB in 1118 allogeneic HSCTs (allo-HSCTs) and 1625 autologous HSCTs (auto-HSCTs) among 54 transplant centers during 2014 (SIGNB-GITMO-AMCLI study). Using logistic regression methods. we identified risk factors for GNB and evaluated the impact of GNB on the 4-month overall-survival after transplant. Results The cumulative incidence of pre-engraftment GNB was 17.3% in allo-HSCT and 9% in auto-HSCT. Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa were the most common isolates. By multivariate analysis, variables associated with GNB were a diagnosis of acute leukemia, a transplant from a HLA-mismatched donor and from cord blood, older age, and duration of severe neutropenia in allo-HSCT, and a diagnosis of lymphoma, older age, and no antibacterial prophylaxis in auto-HSCT. A pretransplant infection by a resistant pathogen was significantly associated with an increased risk of posttransplant infection by the same microorganism in allo-HSCT. Colonization by resistant gram-negative bacteria was significantly associated with an increased rate of infection by the same pathogen in both transplant procedures. GNB was independently associated with increased mortality at 4 months both in allo-HSCT (hazard ratio, 2.13; 95% confidence interval, 1.45–3.13; P Conclusions Pre-engraftment GNB is an independent factor associated with increased mortality rate at 4 months after auto-HSCT and allo-HSCT. Previous infectious history and colonization monitoring represent major indicators of GNB. Clinical Trials registration NCT02088840.

Published
2017

24. Mycobacterium chimaera infections following cardiac surgery in Treviso Hospital, Italy, from 2016 to 2019: Cases report

Author

Inojosa, Walter O, primary, Giobbia, Mario, additional, Muffato, Giovanna, additional, Minniti, Giuseppe, additional, Baldasso, Francesco, additional, Carniato, Antonella, additional, Farina, Francesca, additional, Forner, Gabriella, additional, Rossi, Maria C, additional, Formentini, Stefano, additional, Rigoli, Roberto, additional, and Scotton, Pier G, additional

Published
2019
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26. High rate of transmission in a pulmonary tuberculosis outbreak in a primary school, north-eastern Italy, 2019

Author

Cinquetti, Sandro, primary, Dalmanzio, Maria, additional, Ros, Elisa, additional, Gentili, Davide, additional, Ramigni, Mauro, additional, Grossi, Adriano, additional, Andrianou, Xanthi D, additional, La Torre, Leonardo Ermanno, additional, Rigoli, Roberto, additional, Scotton, Pier Giorgio, additional, Taraschi, Angela, additional, Baldo, Vincenzo, additional, Napoletano, Giuseppina, additional, Russo, Francesca, additional, Pezzotti, Patrizio, additional, Rezza, Giovanni, additional, and Filia, Antonietta, additional

Published
2019
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27. Antifungal susceptibility of invasive yeast isolates in Italy: the GISIA3 study in critically ill patients

Author

Mussap Michele, Manso Ester, Lombardi Gianluigi, Cascio Giuliana, Farina Claudio, Brigante Gioconda, Andreoni Stefano, Amato Gerardino, Iatta Roberta, Borghi Elisa, Morace Giulia, Pecile Patrizia, Rigoli Roberto, Tangorra Elisabetta, Valmarin Maria, and Montagna Maria

Subjects
Infectious and parasitic diseases, RC109-216
Abstract

Abstract Background Yeasts are a common cause of invasive fungal infections in critically ill patients. Antifungal susceptibility testing results of clinically significant fungal strains are of interest to physicians, enabling them to adopt appropriate strategies for empiric and prophylactic therapies. We investigated the antifungal susceptibility of yeasts isolated over a 2-year period from hospitalised patients with invasive yeast infections. Methods 638 yeasts were isolated from the blood, central venous catheters and sterile fluids of 578 patients on general and surgical intensive care units and surgical wards. Etest strips and Sensititre panels were used to test the susceptibility of the isolates to amphotericin B, anidulafungin, caspofungin, fluconazole, itraconazole, posaconazole and voriconazole in 13 laboratories centres (LC) and two co-ordinating centres (CC). The Clinical and Laboratory Standards Institute (CLSI) reference broth microdilution method was used at the CCs for comparison. Results Etest and Sensititre (LC/CC) MIC90 values were, respectively: amphotericin B 0.5/0.38, 1/1 mg/L; anidulafungin 2/1.5 and 1/1 mg/L; caspofungin 1/0.75 and 0.5/0.5 mg/L; fluconazole 12/8 and 16/16 mg/L; itraconazole 1/1.5, 0.5/0.5 mg/L; posaconazole 0.5 mg/L and voriconazole 0.25 mg/L for all. The overall MIC90 values were influenced by the reduced susceptibility of Candida parapsilosis isolates to echinocandins and a reduced or lack of susceptibility of Candida glabrata and Candida krusei to azoles, in particular fluconazole and itraconazole. Comparison of the LC and CC results showed good Essential Agreement (90.3% for Etest and 92.9% for Sensititre), and even higher Categorical Agreement (93.9% for Etest and 96% for Sensititre); differences were observed according to the species, method, and antifungal drug. No cross-resistance between echinocandins and triazoles was detected. Conclusions Our data confirm the different antifungal susceptibility patterns among species, and highlight the need to perform antifungal susceptibility testing of clinically relevant yeasts. With the exception of a few species (e.g. C. glabrata for azoles and C. parapsilosis for echinocandins), the findings of our study suggest that two of the most widely used commercial methods (Etest and Sensititre) provide valid and reproducible results.

Published
2011
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28. Recommendations for the surveillance of multidrug-resistant bacteria in Italian long-term care facilities by the GLISTer working group of the Italian Association of Clinical Microbiologists (AMCLI).

Author

Aschbacher, Richard, Pagani, Leonardo, Migliavacca, Roberta, Pagani, Laura, the GLISTer (Gruppo di Lavoro per lo Studio delle Infezioni nelle Residenze Sanitarie Assistite e Strutture Assimilabili) working group, Confalonieri, Massimo, Farina, Claudio, Fazii, Paolo, Luzzaro, Francesco, Rigoli, Roberto, and Spalla, Melissa

Subjects
LONG-term care facilities, INFECTION control, MICROBIOLOGISTS, INFECTION prevention, MEDICAL personnel
Abstract

Long-term care facilities (LTCFs) are an important reservoir of multidrug-resistant organisms (MDROs). Colonization of LTCF residents by MDROs is generally higher in Italy compared to other European countries. The present review by the working group for the study of infections in LTCFs (GLISTer) of the Italian Association of Clinical Microbiologists (AMCLI) aims to propose criteria for a laboratory-based surveillance of MDROs in Italian LTCFs. We recommend the adhesion to three levels of laboratory-based MDROs surveillance in LTCFs: i) mandatory MDRO surveillance by cumulative retrospective analysis of antimicrobial susceptibility data, obtained as part of routine care of clinical specimens. ii) strongly recommended surveillance by active rectal swab cultures or molecular screening to determine colonization with carbapenemase-producing Enterobacterales, should a resident be proven infected. iii) voluntary surveillance by prospective MDRO surveys, mainly based on point prevalence colonization studies, allowing to determine the MDROs baseline prevalence in the facility. Laboratory-based surveillance of MDROs in LTCFs is aimed at providing useful epidemiological information to healthcare providers operating in the facility, but it is only effective if the collected data are used for infection prevention and control purposes, targeting the peculiar aspects of LTCFs. [ABSTRACT FROM AUTHOR]

Published
2020
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34. Tu1834 Low Levels of Gastrin-17 As a Non-Invasive Marker of GERD

Author

Ferrara, Francesco, primary, Bò, Nadia Dal, additional, Slongo, Tiziana, additional, Rigoli, Roberto, additional, Caroli, Alessandro, additional, Salvat, Helena Heras, additional, Marcello, Roberto, additional, Scarpignato, Carmelo, additional, Savarino, Vincenzo, additional, and Di Mario, Francesco, additional

Published
2013
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35. Sa1988 Recovery of Gastric Function After Helicobacter pylori Eradication and Acetium Administration: A 6 Years Study in Atrophic Gastritis Subjects

Author

Mario, Francesco Di, primary, Rugge, Massimo, additional, Ferrara, Francesco, additional, Bò, Nadia Dal, additional, Slongo, Tiziana, additional, Marcello, Roberto, additional, Salvat, Helena Heras, additional, Guarnieri, Giovanni, additional, Caroli, Alessandro, additional, Rigoli, Roberto, additional, Dei Tos, Angelo Paolo, additional, and Scarpignato, Carmelo, additional

Published
2013
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36. Heterogeneity of West Nile virus genotype 1a in Italy, 2011

Author

Rossini, Giada, primary, Carletti, Fabrizio, additional, Rigoli, Roberto, additional, Piga, Sandro, additional, Bagnarelli, Patrizia, additional, Gaibani, Paolo, additional, Pierro, Anna, additional, Nanni Costa, Alessandro, additional, Grossi, Paolo, additional, Ippolito, Giuseppe, additional, Landini, Maria Paola, additional, Di Caro, Antonino, additional, Capobianchi, Maria Rosaria, additional, and Sambri, Vittorio, additional

Published
2013
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37. Antifungal susceptibility of invasive yeast isolates in Italy: the GISIA3 study in critically ill patients

Author

Morace, Giulia, primary, Borghi, Elisa, additional, Iatta, Roberta, additional, Amato, Gerardino, additional, Andreoni, Stefano, additional, Brigante, Gioconda, additional, Farina, Claudio, additional, Cascio, Giuliana Lo, additional, Lombardi, Gianluigi, additional, Manso, Ester, additional, Mussap, Michele, additional, Pecile, Patrizia, additional, Rigoli, Roberto, additional, Tangorra, Elisabetta, additional, Valmarin, Maria, additional, and Montagna, Maria Teresa, additional

Published
2011
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39. Rhodococcus equi Nosocomial Meningitis Cured by Levofloxacin and Shunt Removal.

Author

Scotton, P. Giorgio, Tonon, Eva, Giobbia, Mario, Gallucci, Maurizio, Rigoli, Roberto, and Vaglia, Alberto

Subjects
MENINGITIS treatment, NOSOCOMIAL infections, QUINOLONE antibacterial agents, THERAPEUTICS
Abstract

Discusses the case of a 51-year-old woman suffering from nosocomial meningitis due to Rhodococcus equi. Placement of external ventricular shunt (EVS) on second day of hospital stay; Replacement of the EVS when septic fever occurred and neurologic condition worsened; No clinical improvement despite vancomycin/rifampicin therapy; Abatement of the fever after a 14-day course of treatment with the fluoroquinolone levofloxacin.

Published
2000
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40. Six-month psychophysical evaluation of olfactory dysfunction in patients with COVID-19

Author

Roberto Rigoli, Anna Menegaldo, Walter Cestaro, Daniele Frezza, Giacomo Spinato, Leonardo Calvanese, Andrea Pettorelli, Anna Menini, Massimo Sonego, Andrea D'Alessandro, Claire Hopkins, Cristoforo Fabbris, Luigi Angelo Vaira, Andy Bertolin, Maria Cristina Da Mosto, Daniele Borsetto, Giancarlo Tirelli, Jerry Polesel, Paolo Boscolo-Rizzo, Boscolo-Rizzo, Paolo, Menegaldo, Anna, Fabbris, Cristoforo, Spinato, Giacomo, Borsetto, Daniele, Vaira, Luigi Angelo, Calvanese, Leonardo, Pettorelli, Andrea, Sonego, Massimo, Frezza, Daniele, Bertolin, Andy, Cestaro, Walter, Rigoli, Roberto, D'Alessandro, Andrea, Tirelli, Giancarlo, Da Mosto, Maria Cristina, Menini, Anna, Polesel, Jerry, and Hopkins, Claire

Subjects
Olfactory system, Adult, Male, Taste, medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), Physiology, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Anosmia, coronavirus, Olfaction, Audiology, AcademicSubjects/SCI01180, Settore BIO/09 - Fisiologia, 03 medical and health sciences, Olfaction Disorders, Behavioral Neuroscience, 0302 clinical medicine, Physiology (medical), medicine, Psychophysics, Humans, In patient, Prospective Studies, 030223 otorhinolaryngology, Aged, business.industry, COVID-19, SARS-CoV-2, anosmia, olfactory function, smell and taste loss, Middle Aged, Sensory Systems, Weak correlation, coronaviru, Smell, 030220 oncology & carcinogenesis, Original Article, Female, Self Report, medicine.symptom, business
Abstract

This study prospectively assessed the 6-month prevalence of self-reported and psychophysically measured olfactory dysfunction in subjects with mild-to-moderate COVID-19. Self-reported smell or taste impairment was prospectively evaluated by SNOT-22 at diagnosis, 4-week, 8-week, and 6-month. At 6 months from the diagnosis, psychophysical evaluation of olfactory function was also performed using the 34-item culturally adapted University of Pennsylvania Smell Identification Test (CA-UPSIT). 145 completed both the 6-month subjective and psychophysical olfactory evaluation. According to CA-UPSIT, 87 subjects (60.0%) exhibited some smell dysfunction, with 10 patients being anosmic (6.9%) and seven being severely microsmic (4.8%). At the time CA-UPSIT was administered, a weak correlation was observed between the self-reported alteration of the sense of smell or taste and olfactory test scores (Spearman’s r = −0.26). Among 112 patients who self-reported normal sense of smell at last follow-up, CA-UPSIT revealed normal smell in 46 (41.1%), mild microsmia in 46 (41.1%), moderate microsmia in 11 (9.8%), severe microsmia in 3 (2.3%), and anosmia in 6 (5.4%) patients; however, of those patients self-reporting normal smell but who were found to have hypofunction on testing, 62 out of 66 had a self-reported reduction in sense of smell or taste at an earlier time point. Despite most patients report a subjectively normal sense of smell, we observed a high percentage of persistent smell dysfunction at 6 months from the diagnosis of syndrome coronavirus 2 (SARS-CoV-2) infection, with 11.7% of patients being anosmic or severely microsmic. These data highlight a significant long-term rate of smell alteration in patients with previous SARS-COV-2 infection.

Published
2021

41. Evolution of Altered Sense of Smell or Taste in Patients With Mildly Symptomatic COVID-19.

Author

Boscolo-Rizzo P, Borsetto D, Fabbris C, Spinato G, Frezza D, Menegaldo A, Mularoni F, Gaudioso P, Cazzador D, Marciani S, Frasconi S, Ferraro M, Berro C, Varago C, Nicolai P, Tirelli G, Da Mosto MC, Obholzer R, Rigoli R, Polesel J, and Hopkins C

Subjects
Adult, Aged, Aged, 80 and over, Cross-Sectional Studies, Female, Humans, Italy epidemiology, Male, Middle Aged, Prevalence, Prospective Studies, Severity of Illness Index, Young Adult, COVID-19 complications, Olfaction Disorders epidemiology, Olfaction Disorders virology, Taste Disorders epidemiology, Taste Disorders virology
Abstract

Importance: An altered sense of smell and taste has been reported to be associated with coronavirus disease 2019 (COVID-19). To understand the evolution of these symptoms during the course of the disease is important to identify patients with persistent loss of smell or taste and estimate the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on the burden of olfactory and gustative dysfunctions., Objective: To evaluate the evolution of the loss of sense of smell and taste in a case series of mildly symptomatic patients with SARS-CoV-2 infection., Design, Setting, and Participants: This cross-sectional survey-based study included 202 mildly symptomatic adults (≥18 years) consecutively assessed at Treviso Regional Hospital, Italy, between March 19 and March 22, 2020, who tested positive for SARS-CoV-2 RNA by polymerase chain reaction on nasopharyngeal and throat swabs., Main Outcomes and Measures: Prevalence of altered sense of smell and taste at follow-up and their variation from baseline., Results: Of 202 patients completing the survey at baseline, 187 (92.6%) also completed the follow-up survey (103 [55.1%] women; median age, 56 years). The evaluation of the evolution of altered sense of smell or taste in the 113 patients reporting sudden onset of these symptoms at baseline showed that 55 patients (48.7%; 95% CI, 39.2-58.3) reported complete resolution of smell or taste impairment, 46 (40.7%; 95% CI, 31.6-50.4) reported an improvement in the severity, and only 12 (10.6%; 95% CI, 5.6-17.8) reported the symptom was unchanged or worse. Persistent loss of smell or taste was not associated with persistent SARS-CoV-2 infection., Conclusions and Relevance: At 4 weeks from the onset, 89% of the SARS-CoV-2-positive mildly symptomatic patients who had had a sudden onset of altered sense of smell or taste experienced a complete resolution or improvement of these symptoms. Persistent loss of smell or taste was not associated with persistent SARS-CoV-2 infection.

Published
2020
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