1,126 results on '"Rinaudo, M"'
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2. MoCRiS a low-cost stratospheric balloon platform to measure the particle flux of cosmic ray showers in the high atmosphere
- Author
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Bocci, V, Brosio, A, Muscio, G, Iacoangeli, F, Liguori, D, Tripodi, M, Alemanno, F, Aloisio, R, Altomare, C, Antolini, R, Aramo, C, Arcaro, C, Barbato, F, Battaglieri, M, Battisti, M, Bau, A, Bellinzona, V, Bernardini, P, Bersani, A, Bertaina, M, Berti, A, Bertucci, B, Bisconti, F, Bissaldi, E, Boezio, M, Boncioli, D, Bondi, M, Bonechi, L, Bonino, R, Bonnoli, G, Bonvicini, V, Bossini, E, Bottino, B, Buscemi, M, Caccianiga, B, Caccianiga, L, Candela, A, Capone, A, Cariello, M, Caruso, R, Cataldi, G, Chiodi, G, Chiodini, G, Colalillo, R, Coluccia, M, Convenga, F, Copello, S, Corosu, M, D'Urso, D, Dal Corso, F, Davini, S, De Deo, M, De Gateano, S, De Laurentis, M, De Mitri, I, De Palma, F, De Vito, E, Dell'Aquila, D, Depaoli, D, Di Luca, A, Di Pierro, F, Di Ruzza, B, Di Santo, M, Di Sciascio, G, Di Venere, L, Dimiccoli, F, Dimitrios, K, Donnini, F, Doro, M, Duranti, M, Evoli, C, Fenu, F, Fontanelli, F, Fusco, P, Gargano, F, Gervasi, M, Giampaoli, A, Giglietto, N, Giordano, F, Gnesi, I, Gonzi, S, Grandi, D, Graziani, M, Hemmer, S, Insolia, A, Iovenitti, S, Ippolito, V, La Vacca, G, La Verde, G, Leonora, E, Levorato, S, Lipari, P, Longo, F, Loparco, F, Lopez Coto, R, Loporchio, S, Marino, A, Marsella, G, Martello, D, Mazziotta, M, Menegolli, A, Miozzi, S, Miyamoto, H, Mocchiutti, E, Morganti, S, Morsani, F, Munini, R, Mussa, R, Nozzoli, F, Nucita, A, Organtini, G, Otto-Nello, G, Pantaleo, F, Paoletti, R, Parodi, F, Perrone, L, Pesenti, L, Petrera, S, Petronio, C, Pillera, R, Pilo, F, Pizzolotto, C, Prandini, E, Pugliese, M, Raino, S, Randazzo, N, Rando, R, Recchia, L, Ricci, E, Rinaudo, M, Rizi, V, Rossi, N, Rozza, D, Salamida, F, Savina, P, Scherini, V, Schioppa, M, Scotti, V, Se-Rini, D, Sipala, V, Surdo, A, Tiberio, A, Tomassetti, N, Tomei, C, Tosta E Melo, I, Turco, P, Vannuccini, E, Vecchiotti, V, Veronesi, I, Zampa, G, Bocci V., Brosio A., Muscio G. G., Iacoangeli F., Liguori D., Tripodi M. A., Alemanno F., Aloisio R., Altomare C., Antolini R., Aramo C., Arcaro C., Barbato F. C. T., Battaglieri M., Battisti M., Bau A., Bellinzona V. E., Bernardini P., Bersani A., Bertaina M., Berti A., Bertucci B., Bisconti F., Bissaldi E., Boezio M., Boncioli D., Bondi M., Bonechi L., Bonino R., Bonnoli G., Bonvicini V., Bossini E., Bottino B., Buscemi M., Caccianiga B., Caccianiga L., Candela A., Capone A., Cariello M., Caruso R., Cataldi G., Chiodi G., Chiodini G., Colalillo R., Coluccia M. R., Convenga F., Copello S., Corosu M., D'Urso D., Dal Corso F., Davini S., De Deo M., De Gateano S., De Laurentis M., De Mitri I., De Palma F., De Vito E., Dell'Aquila D., Depaoli D., Di Luca A., Di Pierro F., Di Ruzza B., Di Santo M., Di Sciascio G., Di Venere L., Dimiccoli F., Dimitrios K., Donnini F., Doro M., Duranti M., Evoli C., Fenu F., Fontanelli F., Fusco P., Gargano F., Gervasi M., Giampaoli A., Giglietto N., Giordano F., Gnesi I., Gonzi S., Grandi D., Graziani M., Hemmer S., Insolia A., Iovenitti S., Ippolito V., La Vacca G., La Verde G., Leonora E., Levorato S., Lipari P., Longo F., Loparco F., Lopez Coto R., Loporchio S., Marino A., Marsella G., Martello D., Mazziotta M. N., Menegolli A., Miozzi S., Miyamoto H., Mocchiutti E., Morganti S., Morsani F., Munini R., Mussa R., Nozzoli F., Nucita A., Organtini G. C., Otto-Nello G., Pantaleo F., Paoletti R., Parodi F., Perrone L., Pesenti L., Petrera S., Petronio C., Pillera R., Pilo F., Pizzolotto C., Prandini E., Pugliese M., Raino S., Randazzo N., Rando R., Recchia L., Ricci E., Rinaudo M., Rizi V., Rossi N., Rozza D., Salamida F., Savina P., Scherini V., Schioppa M., Scotti V., Se-Rini D., Sipala V., Surdo A., Tiberio A., Tomassetti N., Tomei C., Tosta E Melo I., Turco P., Vannuccini E., Vecchiotti V., Veronesi I., Zampa G., Bocci, V, Brosio, A, Muscio, G, Iacoangeli, F, Liguori, D, Tripodi, M, Alemanno, F, Aloisio, R, Altomare, C, Antolini, R, Aramo, C, Arcaro, C, Barbato, F, Battaglieri, M, Battisti, M, Bau, A, Bellinzona, V, Bernardini, P, Bersani, A, Bertaina, M, Berti, A, Bertucci, B, Bisconti, F, Bissaldi, E, Boezio, M, Boncioli, D, Bondi, M, Bonechi, L, Bonino, R, Bonnoli, G, Bonvicini, V, Bossini, E, Bottino, B, Buscemi, M, Caccianiga, B, Caccianiga, L, Candela, A, Capone, A, Cariello, M, Caruso, R, Cataldi, G, Chiodi, G, Chiodini, G, Colalillo, R, Coluccia, M, Convenga, F, Copello, S, Corosu, M, D'Urso, D, Dal Corso, F, Davini, S, De Deo, M, De Gateano, S, De Laurentis, M, De Mitri, I, De Palma, F, De Vito, E, Dell'Aquila, D, Depaoli, D, Di Luca, A, Di Pierro, F, Di Ruzza, B, Di Santo, M, Di Sciascio, G, Di Venere, L, Dimiccoli, F, Dimitrios, K, Donnini, F, Doro, M, Duranti, M, Evoli, C, Fenu, F, Fontanelli, F, Fusco, P, Gargano, F, Gervasi, M, Giampaoli, A, Giglietto, N, Giordano, F, Gnesi, I, Gonzi, S, Grandi, D, Graziani, M, Hemmer, S, Insolia, A, Iovenitti, S, Ippolito, V, La Vacca, G, La Verde, G, Leonora, E, Levorato, S, Lipari, P, Longo, F, Loparco, F, Lopez Coto, R, Loporchio, S, Marino, A, Marsella, G, Martello, D, Mazziotta, M, Menegolli, A, Miozzi, S, Miyamoto, H, Mocchiutti, E, Morganti, S, Morsani, F, Munini, R, Mussa, R, Nozzoli, F, Nucita, A, Organtini, G, Otto-Nello, G, Pantaleo, F, Paoletti, R, Parodi, F, Perrone, L, Pesenti, L, Petrera, S, Petronio, C, Pillera, R, Pilo, F, Pizzolotto, C, Prandini, E, Pugliese, M, Raino, S, Randazzo, N, Rando, R, Recchia, L, Ricci, E, Rinaudo, M, Rizi, V, Rossi, N, Rozza, D, Salamida, F, Savina, P, Scherini, V, Schioppa, M, Scotti, V, Se-Rini, D, Sipala, V, Surdo, A, Tiberio, A, Tomassetti, N, Tomei, C, Tosta E Melo, I, Turco, P, Vannuccini, E, Vecchiotti, V, Veronesi, I, Zampa, G, Bocci V., Brosio A., Muscio G. G., Iacoangeli F., Liguori D., Tripodi M. A., Alemanno F., Aloisio R., Altomare C., Antolini R., Aramo C., Arcaro C., Barbato F. C. T., Battaglieri M., Battisti M., Bau A., Bellinzona V. E., Bernardini P., Bersani A., Bertaina M., Berti A., Bertucci B., Bisconti F., Bissaldi E., Boezio M., Boncioli D., Bondi M., Bonechi L., Bonino R., Bonnoli G., Bonvicini V., Bossini E., Bottino B., Buscemi M., Caccianiga B., Caccianiga L., Candela A., Capone A., Cariello M., Caruso R., Cataldi G., Chiodi G., Chiodini G., Colalillo R., Coluccia M. R., Convenga F., Copello S., Corosu M., D'Urso D., Dal Corso F., Davini S., De Deo M., De Gateano S., De Laurentis M., De Mitri I., De Palma F., De Vito E., Dell'Aquila D., Depaoli D., Di Luca A., Di Pierro F., Di Ruzza B., Di Santo M., Di Sciascio G., Di Venere L., Dimiccoli F., Dimitrios K., Donnini F., Doro M., Duranti M., Evoli C., Fenu F., Fontanelli F., Fusco P., Gargano F., Gervasi M., Giampaoli A., Giglietto N., Giordano F., Gnesi I., Gonzi S., Grandi D., Graziani M., Hemmer S., Insolia A., Iovenitti S., Ippolito V., La Vacca G., La Verde G., Leonora E., Levorato S., Lipari P., Longo F., Loparco F., Lopez Coto R., Loporchio S., Marino A., Marsella G., Martello D., Mazziotta M. N., Menegolli A., Miozzi S., Miyamoto H., Mocchiutti E., Morganti S., Morsani F., Munini R., Mussa R., Nozzoli F., Nucita A., Organtini G. C., Otto-Nello G., Pantaleo F., Paoletti R., Parodi F., Perrone L., Pesenti L., Petrera S., Petronio C., Pillera R., Pilo F., Pizzolotto C., Prandini E., Pugliese M., Raino S., Randazzo N., Rando R., Recchia L., Ricci E., Rinaudo M., Rizi V., Rossi N., Rozza D., Salamida F., Savina P., Scherini V., Schioppa M., Scotti V., Se-Rini D., Sipala V., Surdo A., Tiberio A., Tomassetti N., Tomei C., Tosta E Melo I., Turco P., Vannuccini E., Vecchiotti V., Veronesi I., and Zampa G.
- Abstract
In June 2019 from the region of Calabria (Italy) our group launched the Stratospheric Balloon MoCRiS (Measurement of Cosmic Ray in Stratosphere) that reached up to 35111 meters. MoCRiS is a didactical project that uses a Light Balloon with a payload of only 2.1 Kg payload box included. The capsule was Lithium-ion batteries operated and fully instrumented with two Hi-Res Camera, one for picture and one for video, GPS Tracker, two Particle detectors, and sensors for temperature and pressure. Two ArduSiPM [6] scintillation detectors, made by the INFN group in Rome, were used as cosmic ray flux meters. The technology used for these types of devices makes them very economical, light (<150 g), and with low power consumption (<1 Watt). These characteristics are optimal for use with the balloon and in space (e.g. in CubeSat), and very attractive for educational use, even on the ground. During the school year, the students of the scientific high school "Stefano Patrizi" of Cariati (CS) Italy, participated in the definition of the project following theoretical and practical lessons on aerospace techniques and particle physics with regard to cosmic ray showers in the atmosphere. The mission was completely successful by experimentally verifying the pressure-to-height relation, the height of the thermal inversion in the atmosphere, reaching and exceeding the maximum Regener-Pfotzer level of the shower development. The instrumental and didactic platform created is easily replicable even with further upgrades. We are expanding the collaboration with other schools for further launches.
- Published
- 2022
3. The online laboratories for OCRA - Outreach Cosmic Ray Activities INFN project
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Aramo, C, Antolini, R, Bocci, V, Buscemi, M, Caccianiga, L, Candela, A, Cataldi, G, Colalillo, R, Convenga, F, Coluccia, M, de Palma, F, Di Nezza, P, Di Sciascio, G, Evoli, C, Galbato, G, Hemmer, S, Giampaoli, A, Iacoangeli, F, Liguori, D, Miozzi, S, Paoletti, R, Rossi, N, Rozza, D, Schioppa, M, Veronesi, I, Alemanno, F, Aloisio, R, Altomare, C, Arcaro, C, Barbato, F, Battaglieri, M, Battisti, M, Bau, A, Bellinzona, V, Bernardini, P, Bersani, A, Bertaina, M, Berti, A, Bertucci, B, Bisconti, F, Bissaldi, E, Boezio, M, Boncioli, D, Bondi, M, Bonechi, L, Bonino, R, Bonnoli, G, Bonvicini, V, Bossini, E, Bottino, B, Caccianiga, B, Capone, A, Cariello, M, Caruso, R, Chiodi, G, Chiodini, G, Copello, S, Corosu, M, D'Urso, D, Dal Corso, F, Davini, S, De Deo, M, De Gateano, S, De Laurentis, M, De Mitri, I, De Vito, E, Dell'Aquila, D, Depaoli, D, Di Luca, A, Di Pierro, F, Di Ruzza, B, Di Santo, M, Di Venere, L, Dimiccoli, F, Dimitrios, K, Donnini, F, Doro, M, Duranti, M, Fenu, F, Fontanelli, F, Fusco, P, Gargano, F, Gervasi, M, Giglietto, N, Giordano, F, Gnesi, I, Gonzi, S, Grandi, D, Graziani, M, Insolia, A, Iovenitti, S, Ippolito, V, La Vacca, G, La Verde, G, Leonora, E, Levorato, S, Lipari, P, Longo, F, Loparco, F, Lopez Coto, R, Loporchio, S, Marino, A, Marsella, G, Martello, D, Mazziotta, M, Menegolli, A, Miyamoto, H, Mocchiutti, E, Morganti, S, Morsani, F, Munini, R, Mussa, R, Nozzoli, F, Nucita, A, Organtini, G, Ottonello, G, Pantaleo, F, Parodi, F, Perrone, L, Pesenti, L, Petrera, S, Petronio, C, Pillera, R, Pilo, F, Pizzolotto, C, Prandini, E, Pugliese, M, Raino, S, Randazzo, N, Rando, R, Recchia, L, Ricci, E, Rinaudo, M, Rizi, V, Salamida, F, Savina, P, Scherini, V, Scotti, V, Serini, D, Sipala, V, Surdo, A, Tiberio, A, Tomassetti, N, Tomei, C, Tosta E Melo, I, Turco, P, Vannuccini, E, Vecchiotti, V, Zampa, G, Aramo C., Antolini R., Bocci V., Buscemi M., Caccianiga L., Candela A., Cataldi G., Colalillo R., Convenga F., Coluccia M. R., de Palma F., Di Nezza P., Di Sciascio G., Evoli C., Galbato G., Hemmer S., Giampaoli A., Iacoangeli F., Liguori D., Miozzi S., Paoletti R., Rossi N., Rozza D., Schioppa M., Veronesi I., Alemanno F., Aloisio R., Altomare C., Arcaro C., Barbato F. C. T., Battaglieri M., Battisti M., Bau A., Bellinzona V. E., Bernardini P., Bersani A., Bertaina M., Berti A., Bertucci B., Bisconti F., Bissaldi E., Boezio M., Boncioli D., Bondi M., Bonechi L., Bonino R., Bonnoli G., Bonvicini V., Bossini E., Bottino B., Caccianiga B., Capone A., Cariello M., Caruso R., Chiodi G., Chiodini G., Copello S., Corosu M., D'Urso D., Dal Corso F., Davini S., De Deo M., De Gateano S., De Laurentis M., De Mitri I., De Vito E., Dell'Aquila D., Depaoli D., Di Luca A., Di Pierro F., Di Ruzza B., Di Santo M., Di Venere L., Dimiccoli F., Dimitrios K., Donnini F., Doro M., Duranti M., Fenu F., Fontanelli F., Fusco P., Gargano F., Gervasi M., Giglietto N., Giordano F., Gnesi I., Gonzi S., Grandi D., Graziani M., Insolia A., Iovenitti S., Ippolito V., La Vacca G., La Verde G., Leonora E., Levorato S., Lipari P., Longo F., Loparco F., Lopez Coto R., Loporchio S., Marino A., Marsella G., Martello D., Mazziotta M. N., Menegolli A., Miyamoto H., Mocchiutti E., Morganti S., Morsani F., Munini R., Mussa R., Nozzoli F., Nucita A., Organtini G. C., Ottonello G., Pantaleo F., Parodi F., Perrone L., Pesenti L., Petrera S., Petronio C., Pillera R., Pilo F., Pizzolotto C., Prandini E., Pugliese M., Raino S., Randazzo N., Rando R., Recchia L., Ricci E., Rinaudo M., Rizi V., Salamida F., Savina P., Scherini V., Scotti V., Serini D., Sipala V., Surdo A., Tiberio A., Tomassetti N., Tomei C., Tosta E Melo I., Turco P., Vannuccini E., Vecchiotti V., Zampa G., Aramo, C, Antolini, R, Bocci, V, Buscemi, M, Caccianiga, L, Candela, A, Cataldi, G, Colalillo, R, Convenga, F, Coluccia, M, de Palma, F, Di Nezza, P, Di Sciascio, G, Evoli, C, Galbato, G, Hemmer, S, Giampaoli, A, Iacoangeli, F, Liguori, D, Miozzi, S, Paoletti, R, Rossi, N, Rozza, D, Schioppa, M, Veronesi, I, Alemanno, F, Aloisio, R, Altomare, C, Arcaro, C, Barbato, F, Battaglieri, M, Battisti, M, Bau, A, Bellinzona, V, Bernardini, P, Bersani, A, Bertaina, M, Berti, A, Bertucci, B, Bisconti, F, Bissaldi, E, Boezio, M, Boncioli, D, Bondi, M, Bonechi, L, Bonino, R, Bonnoli, G, Bonvicini, V, Bossini, E, Bottino, B, Caccianiga, B, Capone, A, Cariello, M, Caruso, R, Chiodi, G, Chiodini, G, Copello, S, Corosu, M, D'Urso, D, Dal Corso, F, Davini, S, De Deo, M, De Gateano, S, De Laurentis, M, De Mitri, I, De Vito, E, Dell'Aquila, D, Depaoli, D, Di Luca, A, Di Pierro, F, Di Ruzza, B, Di Santo, M, Di Venere, L, Dimiccoli, F, Dimitrios, K, Donnini, F, Doro, M, Duranti, M, Fenu, F, Fontanelli, F, Fusco, P, Gargano, F, Gervasi, M, Giglietto, N, Giordano, F, Gnesi, I, Gonzi, S, Grandi, D, Graziani, M, Insolia, A, Iovenitti, S, Ippolito, V, La Vacca, G, La Verde, G, Leonora, E, Levorato, S, Lipari, P, Longo, F, Loparco, F, Lopez Coto, R, Loporchio, S, Marino, A, Marsella, G, Martello, D, Mazziotta, M, Menegolli, A, Miyamoto, H, Mocchiutti, E, Morganti, S, Morsani, F, Munini, R, Mussa, R, Nozzoli, F, Nucita, A, Organtini, G, Ottonello, G, Pantaleo, F, Parodi, F, Perrone, L, Pesenti, L, Petrera, S, Petronio, C, Pillera, R, Pilo, F, Pizzolotto, C, Prandini, E, Pugliese, M, Raino, S, Randazzo, N, Rando, R, Recchia, L, Ricci, E, Rinaudo, M, Rizi, V, Salamida, F, Savina, P, Scherini, V, Scotti, V, Serini, D, Sipala, V, Surdo, A, Tiberio, A, Tomassetti, N, Tomei, C, Tosta E Melo, I, Turco, P, Vannuccini, E, Vecchiotti, V, Zampa, G, Aramo C., Antolini R., Bocci V., Buscemi M., Caccianiga L., Candela A., Cataldi G., Colalillo R., Convenga F., Coluccia M. R., de Palma F., Di Nezza P., Di Sciascio G., Evoli C., Galbato G., Hemmer S., Giampaoli A., Iacoangeli F., Liguori D., Miozzi S., Paoletti R., Rossi N., Rozza D., Schioppa M., Veronesi I., Alemanno F., Aloisio R., Altomare C., Arcaro C., Barbato F. C. T., Battaglieri M., Battisti M., Bau A., Bellinzona V. E., Bernardini P., Bersani A., Bertaina M., Berti A., Bertucci B., Bisconti F., Bissaldi E., Boezio M., Boncioli D., Bondi M., Bonechi L., Bonino R., Bonnoli G., Bonvicini V., Bossini E., Bottino B., Caccianiga B., Capone A., Cariello M., Caruso R., Chiodi G., Chiodini G., Copello S., Corosu M., D'Urso D., Dal Corso F., Davini S., De Deo M., De Gateano S., De Laurentis M., De Mitri I., De Vito E., Dell'Aquila D., Depaoli D., Di Luca A., Di Pierro F., Di Ruzza B., Di Santo M., Di Venere L., Dimiccoli F., Dimitrios K., Donnini F., Doro M., Duranti M., Fenu F., Fontanelli F., Fusco P., Gargano F., Gervasi M., Giglietto N., Giordano F., Gnesi I., Gonzi S., Grandi D., Graziani M., Insolia A., Iovenitti S., Ippolito V., La Vacca G., La Verde G., Leonora E., Levorato S., Lipari P., Longo F., Loparco F., Lopez Coto R., Loporchio S., Marino A., Marsella G., Martello D., Mazziotta M. N., Menegolli A., Miyamoto H., Mocchiutti E., Morganti S., Morsani F., Munini R., Mussa R., Nozzoli F., Nucita A., Organtini G. C., Ottonello G., Pantaleo F., Parodi F., Perrone L., Pesenti L., Petrera S., Petronio C., Pillera R., Pilo F., Pizzolotto C., Prandini E., Pugliese M., Raino S., Randazzo N., Rando R., Recchia L., Ricci E., Rinaudo M., Rizi V., Salamida F., Savina P., Scherini V., Scotti V., Serini D., Sipala V., Surdo A., Tiberio A., Tomassetti N., Tomei C., Tosta E Melo I., Turco P., Vannuccini E., Vecchiotti V., and Zampa G.
- Abstract
OCRA - Outreach Cosmic Ray Activities was born in 2018 as a national outreach project of INFN with the aim of collecting, within a national framework, the numerous public engagement activities in the field of cosmic ray physics already present at a local level in the divisions and laboratories. Since spring 2020 OCRA offers also a series of online laboratories on its website https://web.infn.it/OCRA/, designed not only to be used by students individually but also to be offered in the classroom by teachers. The cosmic ray path, present on the website, will be presented together with the online laboratories on the measurement of muons, from the one related to the dependence on the zenith angle made during the International Cosmic Day up to measurements of the flux dependency on the altitude in the atmosphere and in the water. Also, a laboratory allowing to analyze public data of the Pierre Auger Observatory will be presented. In addition, some teaching methods included in the "Teachers' area" of the OCRA website will be described. The developed cosmic ray path was also used to organize an online course for teachers of Italian high schools with the purpose of accompanying teachers when approaching the subject for the first time. About 70 teachers participated for a total of 9 lessons. ã Copyright owned by the author(s) under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND 4.0)
- Published
- 2022
4. Discovering cosmic rays with OCRA: outreach activities for students and teachers
- Author
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Hemmer, S, Aramo, C, Bissaldi, E, Bocci, V, Bottino, B, Buscemi, M, Caccianiga, L, Cataldi, G, Dimiccoli, F, Di Pierro, F, Evoli, C, Giampaoli, A, La Vacca, G, Menegolli, A, Miozzi, S, Morsani, F, Munini, R, Paoletti, R, Rozza, D, Schioppa, M, Tomassetti, N, Vannuccini, E, Alemanno, F, Aloisio, R, Altomare, C, Antolini, R, Arcaro, C, Barbato, F, Battaglieri, M, Battisti, M, Bau, A, Bellinzona, V, Bernardini, P, Bersani, A, Bertaina, M, Berti, A, Bertucci, B, Bisconti, F, Boezio, M, Boncioli, D, Bondi, M, Bonechi, L, Bonino, R, Bonnoli, G, Bonvicini, V, Bossini, E, Caccianiga, B, Candela, A, Capone, A, Cariello, M, Caruso, R, Chiodi, G, Chiodini, G, Colalillo, R, Coluccia, M, Convenga, F, Copello, S, Corosu, M, D'Urso, D, Dal Corso, F, Davini, S, De Deo, M, De Gateano, S, De Laurentis, M, De Mitri, I, De Palma, F, De Vito, E, Dell'Aquila, D, Depaoli, D, Di Luca, A, Di Ruzza, B, Di Santo, M, Di Sciascio, G, Di Venere, L, Dimitrios, K, Donnini, F, Doro, M, Duranti, M, Fenu, F, Fontanelli, F, Fusco, P, Gargano, F, Gervasi, M, Giglietto, N, Giordano, F, Gnesi, I, Gonzi, S, Grandi, D, Graziani, M, Iacoangeli, F, Insolia, A, Iovenitti, S, Ippolito, V, La Verde, G, Leonora, E, Levorato, S, Liguori, D, Lipari, P, Longo, F, Loparco, F, Lopez Coto, R, Loporchio, S, Marino, A, Marsella, G, Martello, D, Mazziotta, M, Miyamoto, H, Mocchiutti, E, Morganti, S, Mussa, R, Nozzoli, F, Nucita, A, Organtini, G, Ottonello, G, Pantaleo, F, Parodi, F, Perrone, L, Pesenti, L, Petrera, S, Petronio, C, Pillera, R, Pilo, F, Pizzolotto, C, Prandini, E, Pugliese, M, Raino, S, Randazzo, N, Rando, R, Recchia, L, Ricci, E, Rinaudo, M, Rizi, V, Rossi, N, Salamida, F, Savina, P, Scherini, V, Scotti, V, Serini, D, Sipala, V, Surdo, A, Tiberio, A, Tomei, C, Tosta E Melo, I, Turco, P, Vecchiotti, V, Veronesi, I, Zampa, G, Hemmer S., Aramo C., Bissaldi E., Bocci V., Bottino B., Buscemi M., Caccianiga L., Cataldi G., Dimiccoli F., Di Pierro F., Evoli C., Giampaoli A., La Vacca G., Menegolli A., Miozzi S., Morsani F., Munini R., Paoletti R., Rozza D., Schioppa M., Tomassetti N., Vannuccini E., Alemanno F., Aloisio R., Altomare C., Antolini R., Arcaro C., Barbato F. C. T., Battaglieri M., Battisti M., Bau A., Bellinzona V. E., Bernardini P., Bersani A., Bertaina M., Berti A., Bertucci B., Bisconti F., Boezio M., Boncioli D., Bondi M., Bonechi L., Bonino R., Bonnoli G., Bonvicini V., Bossini E., Caccianiga B., Candela A., Capone A., Cariello M., Caruso R., Chiodi G., Chiodini G., Colalillo R., Coluccia M. R., Convenga F., Copello S., Corosu M., D'Urso D., Dal Corso F., Davini S., De Deo M., De Gateano S., De Laurentis M., De Mitri I., De Palma F., De Vito E., Dell'Aquila D., Depaoli D., Di Luca A., Di Ruzza B., Di Santo M., Di Sciascio G., Di Venere L., Dimitrios K., Donnini F., Doro M., Duranti M., Fenu F., Fontanelli F., Fusco P., Gargano F., Gervasi M., Giglietto N., Giordano F., Gnesi I., Gonzi S., Grandi D., Graziani M., Iacoangeli F., Insolia A., Iovenitti S., Ippolito V., La Verde G., Leonora E., Levorato S., Liguori D., Lipari P., Longo F., Loparco F., Lopez Coto R., Loporchio S., Marino A., Marsella G., Martello D., Mazziotta M. N., Miyamoto H., Mocchiutti E., Morganti S., Mussa R., Nozzoli F., Nucita A., Organtini G. C., Ottonello G., Pantaleo F., Parodi F., Perrone L., Pesenti L., Petrera S., Petronio C., Pillera R., Pilo F., Pizzolotto C., Prandini E., Pugliese M., Raino S., Randazzo N., Rando R., Recchia L., Ricci E., Rinaudo M., Rizi V., Rossi N., Salamida F., Savina P., Scherini V., Scotti V., Serini D., Sipala V., Surdo A., Tiberio A., Tomei C., Tosta E Melo I., Turco P., Vecchiotti V., Veronesi I., Zampa G., Hemmer, S, Aramo, C, Bissaldi, E, Bocci, V, Bottino, B, Buscemi, M, Caccianiga, L, Cataldi, G, Dimiccoli, F, Di Pierro, F, Evoli, C, Giampaoli, A, La Vacca, G, Menegolli, A, Miozzi, S, Morsani, F, Munini, R, Paoletti, R, Rozza, D, Schioppa, M, Tomassetti, N, Vannuccini, E, Alemanno, F, Aloisio, R, Altomare, C, Antolini, R, Arcaro, C, Barbato, F, Battaglieri, M, Battisti, M, Bau, A, Bellinzona, V, Bernardini, P, Bersani, A, Bertaina, M, Berti, A, Bertucci, B, Bisconti, F, Boezio, M, Boncioli, D, Bondi, M, Bonechi, L, Bonino, R, Bonnoli, G, Bonvicini, V, Bossini, E, Caccianiga, B, Candela, A, Capone, A, Cariello, M, Caruso, R, Chiodi, G, Chiodini, G, Colalillo, R, Coluccia, M, Convenga, F, Copello, S, Corosu, M, D'Urso, D, Dal Corso, F, Davini, S, De Deo, M, De Gateano, S, De Laurentis, M, De Mitri, I, De Palma, F, De Vito, E, Dell'Aquila, D, Depaoli, D, Di Luca, A, Di Ruzza, B, Di Santo, M, Di Sciascio, G, Di Venere, L, Dimitrios, K, Donnini, F, Doro, M, Duranti, M, Fenu, F, Fontanelli, F, Fusco, P, Gargano, F, Gervasi, M, Giglietto, N, Giordano, F, Gnesi, I, Gonzi, S, Grandi, D, Graziani, M, Iacoangeli, F, Insolia, A, Iovenitti, S, Ippolito, V, La Verde, G, Leonora, E, Levorato, S, Liguori, D, Lipari, P, Longo, F, Loparco, F, Lopez Coto, R, Loporchio, S, Marino, A, Marsella, G, Martello, D, Mazziotta, M, Miyamoto, H, Mocchiutti, E, Morganti, S, Mussa, R, Nozzoli, F, Nucita, A, Organtini, G, Ottonello, G, Pantaleo, F, Parodi, F, Perrone, L, Pesenti, L, Petrera, S, Petronio, C, Pillera, R, Pilo, F, Pizzolotto, C, Prandini, E, Pugliese, M, Raino, S, Randazzo, N, Rando, R, Recchia, L, Ricci, E, Rinaudo, M, Rizi, V, Rossi, N, Salamida, F, Savina, P, Scherini, V, Scotti, V, Serini, D, Sipala, V, Surdo, A, Tiberio, A, Tomei, C, Tosta E Melo, I, Turco, P, Vecchiotti, V, Veronesi, I, Zampa, G, Hemmer S., Aramo C., Bissaldi E., Bocci V., Bottino B., Buscemi M., Caccianiga L., Cataldi G., Dimiccoli F., Di Pierro F., Evoli C., Giampaoli A., La Vacca G., Menegolli A., Miozzi S., Morsani F., Munini R., Paoletti R., Rozza D., Schioppa M., Tomassetti N., Vannuccini E., Alemanno F., Aloisio R., Altomare C., Antolini R., Arcaro C., Barbato F. C. T., Battaglieri M., Battisti M., Bau A., Bellinzona V. E., Bernardini P., Bersani A., Bertaina M., Berti A., Bertucci B., Bisconti F., Boezio M., Boncioli D., Bondi M., Bonechi L., Bonino R., Bonnoli G., Bonvicini V., Bossini E., Caccianiga B., Candela A., Capone A., Cariello M., Caruso R., Chiodi G., Chiodini G., Colalillo R., Coluccia M. R., Convenga F., Copello S., Corosu M., D'Urso D., Dal Corso F., Davini S., De Deo M., De Gateano S., De Laurentis M., De Mitri I., De Palma F., De Vito E., Dell'Aquila D., Depaoli D., Di Luca A., Di Ruzza B., Di Santo M., Di Sciascio G., Di Venere L., Dimitrios K., Donnini F., Doro M., Duranti M., Fenu F., Fontanelli F., Fusco P., Gargano F., Gervasi M., Giglietto N., Giordano F., Gnesi I., Gonzi S., Grandi D., Graziani M., Iacoangeli F., Insolia A., Iovenitti S., Ippolito V., La Verde G., Leonora E., Levorato S., Liguori D., Lipari P., Longo F., Loparco F., Lopez Coto R., Loporchio S., Marino A., Marsella G., Martello D., Mazziotta M. N., Miyamoto H., Mocchiutti E., Morganti S., Mussa R., Nozzoli F., Nucita A., Organtini G. C., Ottonello G., Pantaleo F., Parodi F., Perrone L., Pesenti L., Petrera S., Petronio C., Pillera R., Pilo F., Pizzolotto C., Prandini E., Pugliese M., Raino S., Randazzo N., Rando R., Recchia L., Ricci E., Rinaudo M., Rizi V., Rossi N., Salamida F., Savina P., Scherini V., Scotti V., Serini D., Sipala V., Surdo A., Tiberio A., Tomei C., Tosta E Melo I., Turco P., Vecchiotti V., Veronesi I., and Zampa G.
- Abstract
The Outreach Cosmic Ray Activities (OCRA) project offers a platform for all outreach activities focusing on cosmic rays within the Italian Istituto Nazionale di Fisica Nucleare (INFN). Created in 2018, OCRA now counts 21 of the institute's divisions all over Italy as members. The project's core activity is the participation of all its members in the International Cosmic Day, organized by DESY, and inviting high school students to carry out hands-on measurements of the cosmic ray flux and learn about the related physics background. Two students from each division are then selected to participate in the annual OCRA science camp, a three-day full immersion into the life of a physicist. The national activities are complemented by local initiatives of the OCRA member groups: workshops and tutorship programs, science competitions and the development of new detectors for outreach activities offer a multitude of possibilities for students to engage with our researchers and to explore the world of cosmic rays. Since spring of 2020 OCRA also offers a series of online laboratories on its website https://web.infn.it/OCRA/, designed not only to be used by students individually but also to be used in the classroom by teachers. Here we will give an overview on all activities offered by OCRA with a particular focus on the 2020 online event organized in occasion of the International Cosmic Day, that saw the participation of more than 3000 students.
- Published
- 2022
5. “A scuola di Astroparticelle”: a synergy between school education and scientific research
- Author
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Colalillo, R, Aramo, C, Alemanno, F, Aloisio, R, Altomare, C, Antolini, R, Arcaro, C, Barbato, F, Battaglieri, M, Battisti, M, Bau, A, Bellinzona, V, Bernardini, P, Bersani, A, Bertaina, M, Berti, A, Bertucci, B, Bisconti, F, Bissaldi, E, Bocci, V, Boezio, M, Boncioli, D, Bondi, M, Bonechi, L, Bonino, R, Bonnoli, G, Bonvicini, V, Bossini, E, Bottino, B, Buscemi, M, Caccianiga, B, Caccianiga, L, Candela, A, Capone, A, Cariello, M, Caruso, R, Cataldi, G, Chiodi, G, Chiodini, G, Coluccia, M, Convenga, F, Copello, S, Corosu, M, D'Urso, D, Dal Corso, F, Davini, S, De Deo, M, De Gateano, S, De Laurentis, M, De Mitri, I, De Palma, F, De Vito, E, Dell'Aquila, D, Depaoli, D, Di Luca, A, Di Pierro, F, Di Ruzza, B, Di Santo, M, Di Sciascio, G, Di Venere, L, Dimiccoli, F, Dimitrios, K, Donnini, F, Doro, M, Duranti, M, Evoli, C, Fenu, F, Fontanelli, F, Fusco, P, Gargano, F, Gervasi, M, Giampaoli, A, Giglietto, N, Giordano, F, Gnesi, I, Gonzi, S, Grandi, D, Graziani, M, Hemmer, S, Iacoangeli, F, Insolia, A, Iovenitti, S, Ippolito, V, La Vacca, G, La Verde, G, Leonora, E, Levorato, S, Liguori, D, Lipari, P, Longo, F, Loparco, F, Lopez Coto, R, Loporchio, S, Marino, A, Marsella, G, Martello, D, Mazziotta, M, Menegolli, A, Miozzi, S, Miyamoto, H, Mocchiutti, E, Morganti, S, Morsani, F, Munini, R, Mussa, R, Nozzoli, F, Nucita, A, Organtini, G, Ottonello, G, Pantaleo, F, Paoletti, R, Parodi, F, Perrone, L, Pesenti, L, Petrera, S, Petronio, C, Pillera, R, Pilo, F, Pizzolotto, C, Prandini, E, Pugliese, M, Raino, S, Randazzo, N, Rando, R, Recchia, L, Ricci, E, Rinaudo, M, Rizi, V, Rossi, N, Rozza, D, Salamida, F, Savina, P, Scherini, V, Schioppa, M, Scotti, V, Serini, D, Sipala, V, Surdo, A, Tiberio, A, Tomassetti, N, Tomei, C, Tosta E Melo, I, Turco, P, Vannuccini, E, Vecchiotti, V, Veronesi, I, Zampa, G, Colalillo R., Aramo C., Alemanno F., Aloisio R., Altomare C., Antolini R., Arcaro C., Barbato F. C. T., Battaglieri M., Battisti M., Bau A., Bellinzona V. E., Bernardini P., Bersani A., Bertaina M., Berti A., Bertucci B., Bisconti F., Bissaldi E., Bocci V., Boezio M., Boncioli D., Bondi M., Bonechi L., Bonino R., Bonnoli G., Bonvicini V., Bossini E., Bottino B., Buscemi M., Caccianiga B., Caccianiga L., Candela A., Capone A., Cariello M., Caruso R., Cataldi G., Chiodi G., Chiodini G., Coluccia M. R., Convenga F., Copello S., Corosu M., D'Urso D., Dal Corso F., Davini S., De Deo M., De Gateano S., De Laurentis M., De Mitri I., De Palma F., De Vito E., Dell'Aquila D., Depaoli D., Di Luca A., Di Pierro F., Di Ruzza B., Di Santo M., Di Sciascio G., Di Venere L., Dimiccoli F., Dimitrios K., Donnini F., Doro M., Duranti M., Evoli C., Fenu F., Fontanelli F., Fusco P., Gargano F., Gervasi M., Giampaoli A., Giglietto N., Giordano F., Gnesi I., Gonzi S., Grandi D., Graziani M., Hemmer S., Iacoangeli F., Insolia A., Iovenitti S., Ippolito V., La Vacca G., La Verde G., Leonora E., Levorato S., Liguori D., Lipari P., Longo F., Loparco F., Lopez Coto R., Loporchio S., Marino A., Marsella G., Martello D., Mazziotta M. N., Menegolli A., Miozzi S., Miyamoto H., Mocchiutti E., Morganti S., Morsani F., Munini R., Mussa R., Nozzoli F., Nucita A., Organtini G. C., Ottonello G., Pantaleo F., Paoletti R., Parodi F., Perrone L., Pesenti L., Petrera S., Petronio C., Pillera R., Pilo F., Pizzolotto C., Prandini E., Pugliese M., Raino S., Randazzo N., Rando R., Recchia L., Ricci E., Rinaudo M., Rizi V., Rossi N., Rozza D., Salamida F., Savina P., Scherini V., Schioppa M., Scotti V., Serini D., Sipala V., Surdo A., Tiberio A., Tomassetti N., Tomei C., Tosta E Melo I., Turco P., Vannuccini E., Vecchiotti V., Veronesi I., Zampa G., Colalillo, R, Aramo, C, Alemanno, F, Aloisio, R, Altomare, C, Antolini, R, Arcaro, C, Barbato, F, Battaglieri, M, Battisti, M, Bau, A, Bellinzona, V, Bernardini, P, Bersani, A, Bertaina, M, Berti, A, Bertucci, B, Bisconti, F, Bissaldi, E, Bocci, V, Boezio, M, Boncioli, D, Bondi, M, Bonechi, L, Bonino, R, Bonnoli, G, Bonvicini, V, Bossini, E, Bottino, B, Buscemi, M, Caccianiga, B, Caccianiga, L, Candela, A, Capone, A, Cariello, M, Caruso, R, Cataldi, G, Chiodi, G, Chiodini, G, Coluccia, M, Convenga, F, Copello, S, Corosu, M, D'Urso, D, Dal Corso, F, Davini, S, De Deo, M, De Gateano, S, De Laurentis, M, De Mitri, I, De Palma, F, De Vito, E, Dell'Aquila, D, Depaoli, D, Di Luca, A, Di Pierro, F, Di Ruzza, B, Di Santo, M, Di Sciascio, G, Di Venere, L, Dimiccoli, F, Dimitrios, K, Donnini, F, Doro, M, Duranti, M, Evoli, C, Fenu, F, Fontanelli, F, Fusco, P, Gargano, F, Gervasi, M, Giampaoli, A, Giglietto, N, Giordano, F, Gnesi, I, Gonzi, S, Grandi, D, Graziani, M, Hemmer, S, Iacoangeli, F, Insolia, A, Iovenitti, S, Ippolito, V, La Vacca, G, La Verde, G, Leonora, E, Levorato, S, Liguori, D, Lipari, P, Longo, F, Loparco, F, Lopez Coto, R, Loporchio, S, Marino, A, Marsella, G, Martello, D, Mazziotta, M, Menegolli, A, Miozzi, S, Miyamoto, H, Mocchiutti, E, Morganti, S, Morsani, F, Munini, R, Mussa, R, Nozzoli, F, Nucita, A, Organtini, G, Ottonello, G, Pantaleo, F, Paoletti, R, Parodi, F, Perrone, L, Pesenti, L, Petrera, S, Petronio, C, Pillera, R, Pilo, F, Pizzolotto, C, Prandini, E, Pugliese, M, Raino, S, Randazzo, N, Rando, R, Recchia, L, Ricci, E, Rinaudo, M, Rizi, V, Rossi, N, Rozza, D, Salamida, F, Savina, P, Scherini, V, Schioppa, M, Scotti, V, Serini, D, Sipala, V, Surdo, A, Tiberio, A, Tomassetti, N, Tomei, C, Tosta E Melo, I, Turco, P, Vannuccini, E, Vecchiotti, V, Veronesi, I, Zampa, G, Colalillo R., Aramo C., Alemanno F., Aloisio R., Altomare C., Antolini R., Arcaro C., Barbato F. C. T., Battaglieri M., Battisti M., Bau A., Bellinzona V. E., Bernardini P., Bersani A., Bertaina M., Berti A., Bertucci B., Bisconti F., Bissaldi E., Bocci V., Boezio M., Boncioli D., Bondi M., Bonechi L., Bonino R., Bonnoli G., Bonvicini V., Bossini E., Bottino B., Buscemi M., Caccianiga B., Caccianiga L., Candela A., Capone A., Cariello M., Caruso R., Cataldi G., Chiodi G., Chiodini G., Coluccia M. R., Convenga F., Copello S., Corosu M., D'Urso D., Dal Corso F., Davini S., De Deo M., De Gateano S., De Laurentis M., De Mitri I., De Palma F., De Vito E., Dell'Aquila D., Depaoli D., Di Luca A., Di Pierro F., Di Ruzza B., Di Santo M., Di Sciascio G., Di Venere L., Dimiccoli F., Dimitrios K., Donnini F., Doro M., Duranti M., Evoli C., Fenu F., Fontanelli F., Fusco P., Gargano F., Gervasi M., Giampaoli A., Giglietto N., Giordano F., Gnesi I., Gonzi S., Grandi D., Graziani M., Hemmer S., Iacoangeli F., Insolia A., Iovenitti S., Ippolito V., La Vacca G., La Verde G., Leonora E., Levorato S., Liguori D., Lipari P., Longo F., Loparco F., Lopez Coto R., Loporchio S., Marino A., Marsella G., Martello D., Mazziotta M. N., Menegolli A., Miozzi S., Miyamoto H., Mocchiutti E., Morganti S., Morsani F., Munini R., Mussa R., Nozzoli F., Nucita A., Organtini G. C., Ottonello G., Pantaleo F., Paoletti R., Parodi F., Perrone L., Pesenti L., Petrera S., Petronio C., Pillera R., Pilo F., Pizzolotto C., Prandini E., Pugliese M., Raino S., Randazzo N., Rando R., Recchia L., Ricci E., Rinaudo M., Rizi V., Rossi N., Rozza D., Salamida F., Savina P., Scherini V., Schioppa M., Scotti V., Serini D., Sipala V., Surdo A., Tiberio A., Tomassetti N., Tomei C., Tosta E Melo I., Turco P., Vannuccini E., Vecchiotti V., Veronesi I., and Zampa G.
- Abstract
The outreach program “A scuola di Astroparticelle” was proposed in 2016 by the National Institute for Nuclear Physics (INFN - Napoli Division) in collaboration with the Physics Department “Ettore Pancini” of the Federico II University in Napoli, CNR-SPIN and CNR-ISASI Institutes. Its main goal is to engage teachers and students of High Schools in astroparticle physics projects. For the third edition (2018/19), the activities, which are also part of the Italian Educational Program PCTO - “Percorsi per le Competenze Trasversali e per l'Orientamento”, involved 18 schools for a total of 21 projects on several topics. Some projects were strictly related to astroparticles as cosmic rays, while others were more technical, as the development of particle detectors, or cross-disciplinary projects. Students worked for the entire school year and prepared materials for the final event. More than 600 students attended the event and presented their work to a jury with a poster and an oral presentation in plenary sessions. Since 2018, the program is part of OCRA - Outreach Cosmic Ray Activities - a national outreach project of INFN with the aim of collecting, within a common framework, the numerous outreach activities in cosmic-ray field carried out at the local level. The fourth edition (2019-20), in spite of the difficult situation due to the COVID-19 pandemic, has also seen the participation of 22 schools that carried out part of the activities in an online format. The project realized using the open data of the Pierre Auger Observatory will be presented in detail.
- Published
- 2022
6. Training teachers on new topics and new tools in Physics education.
- Author
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Piccione, A, Massa, A A, Ruggiero, M L, Serio, M, Rinaudo, M, Marocchi, D, and Marino, T
- Published
- 2023
- Full Text
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7. Discovering cosmic rays with OCRA: outreach activities for students and teachers
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Hemmer, S., Aramo, C., Bissaldi, E., Bocci, V., Bottino, B., Buscemi, M., Caccianiga, L., Cataldi, G., Dimiccoli, F., Di Pierro, F., Evoli, C., Giampaoli, A., La Vacca, G., Menegolli, A., Miozzi, S., Morsani, F., Munini, R., Paoletti, R., Rozza, D., Schioppa, M., Tomassetti, N., Vannuccini, E., Alemanno, F., Aloisio, R., Altomare, C., Antolini, R., Arcaro, C., Barbato, F. C. T., Battaglieri, M., Battisti, M., Bau, A., Bellinzona, V. E., Bernardini, P., Bersani, A., Bertaina, M., Berti, A., Bertucci, B., Bisconti, F., Boezio, M., Boncioli, D., Bondì, M., Bonechi, L., Bonino, R., Bonnoli, G., Bonvicini, V., Bossini, E., Caccianiga, B., Candela, A., Capone, A., Cariello, M., Caruso, R., Chiodi, G., Chiodini, G., Colalillo, R., Coluccia, M. R., Convenga, F., Copello, S., Corosu, M., D Urso, D., Dal Corso, F., Davini, S., Deo, M., Gateano, S., Laurentis, M., Mitri, I., Palma, F., Vito, E., Aquila, D., Depaoli, D., Di Luca, A., Di Ruzza, B., Di Santo, M., Di Sciascio, G., Di Venere, L., Dimitrios, K., Donnini, F., Doro, M., Duranti, M., Fenu, F., Fontanelli, F., Fusco, P., Gargano, F., Gervasi, M., Giglietto, N., Giordano, F., Gnesi, I., Gonzi, S., Grandi, D., Graziani, M., Iacoangeli, F., Insolia, A., Iovenitti, S., Ippolito, V., La Verde, G., Leonora, E., Levorato, S., Liguori, D., Lipari, P., Longo, F., Loparco, F., Lopez Coto, R., Loporchio, S., Marino, A., Marsella, G., Martello, D., Mazziotta, M. N., Miyamoto, H., Mocchiutti, E., Morganti, S., Mussa, R., Nozzoli, F., Nucita, A., Organtini, G. C., Ottonello, G., Pantaleo, F., Parodi, F., Perrone, L., Pesenti, L., Petrera, S., Petronio, C., Pillera, R., Pilo, F., Pizzolotto, C., Prandini, E., Pugliese, M., Rainò, S., Randazzo, N., Rando, R., Recchia, L., Ricci, E., Rinaudo, M., Rizi, V., Rossi, N., Salamida, F., Savina, P., Scherini, V., Scotti, V., Serini, D., Sipala, V., Surdo, A., Tiberio, A., Tomei, C., Iara Tosta e Melo, Turco, P., Vecchiotti, V., Veronesi, I., Zampa, G., Hemmer, S, Aramo, C, Bissaldi, E, Bocci, V, Bottino, B, Buscemi, M, Caccianiga, L, Cataldi, G, Dimiccoli, F, Di Pierro, F, Evoli, C, Giampaoli, A, La Vacca, G, Menegolli, A, Miozzi, S, Morsani, F, Munini, R, Paoletti, R, Rozza, D, Schioppa, M, Tomassetti, N, Vannuccini, E, Alemanno, F, Aloisio, R, Altomare, C, Antolini, R, Arcaro, C, Barbato, F, Battaglieri, M, Battisti, M, Bau, A, Bellinzona, V, Bernardini, P, Bersani, A, Bertaina, M, Berti, A, Bertucci, B, Bisconti, F, Boezio, M, Boncioli, D, Bondi, M, Bonechi, L, Bonino, R, Bonnoli, G, Bonvicini, V, Bossini, E, Caccianiga, B, Candela, A, Capone, A, Cariello, M, Caruso, R, Chiodi, G, Chiodini, G, Colalillo, R, Coluccia, M, Convenga, F, Copello, S, Corosu, M, D'Urso, D, Dal Corso, F, Davini, S, De Deo, M, De Gateano, S, De Laurentis, M, De Mitri, I, De Palma, F, De Vito, E, Dell'Aquila, D, Depaoli, D, Di Luca, A, Di Ruzza, B, Di Santo, M, Di Sciascio, G, Di Venere, L, Dimitrios, K, Donnini, F, Doro, M, Duranti, M, Fenu, F, Fontanelli, F, Fusco, P, Gargano, F, Gervasi, M, Giglietto, N, Giordano, F, Gnesi, I, Gonzi, S, Grandi, D, Graziani, M, Iacoangeli, F, Insolia, A, Iovenitti, S, Ippolito, V, La Verde, G, Leonora, E, Levorato, S, Liguori, D, Lipari, P, Longo, F, Loparco, F, Lopez Coto, R, Loporchio, S, Marino, A, Marsella, G, Martello, D, Mazziotta, M, Miyamoto, H, Mocchiutti, E, Morganti, S, Mussa, R, Nozzoli, F, Nucita, A, Organtini, G, Ottonello, G, Pantaleo, F, Parodi, F, Perrone, L, Pesenti, L, Petrera, S, Petronio, C, Pillera, R, Pilo, F, Pizzolotto, C, Prandini, E, Pugliese, M, Raino, S, Randazzo, N, Rando, R, Recchia, L, Ricci, E, Rinaudo, M, Rizi, V, Rossi, N, Salamida, F, Savina, P, Scherini, V, Scotti, V, Serini, D, Sipala, V, Surdo, A, Tiberio, A, Tomei, C, Tosta E Melo, I, Turco, P, Vecchiotti, V, Veronesi, I, and Zampa, G
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cosmic rays - Abstract
The Outreach Cosmic Ray Activities (OCRA) project offers a platform for all outreach activities focusing on cosmic rays within the Italian Istituto Nazionale di Fisica Nucleare (INFN). Created in 2018, OCRA now counts 21 of the institute's divisions all over Italy as members. The project's core activity is the participation of all its members in the International Cosmic Day, organized by DESY, and inviting high school students to carry out hands-on measurements of the cosmic ray flux and learn about the related physics background. Two students from each division are then selected to participate in the annual OCRA science camp, a three-day full immersion into the life of a physicist. The national activities are complemented by local initiatives of the OCRA member groups: workshops and tutorship programs, science competitions and the development of new detectors for outreach activities offer a multitude of possibilities for students to engage with our researchers and to explore the world of cosmic rays. Since spring of 2020 OCRA also offers a series of online laboratories on its website https://web.infn.it/OCRA/, designed not only to be used by students individually but also to be used in the classroom by teachers. Here we will give an overview on all activities offered by OCRA with a particular focus on the 2020 online event organized in occasion of the International Cosmic Day, that saw the participation of more than 3000 students.
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- 2022
8. Immunoproteasome Activity in the Nervous System
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Rinaudo, M. T., Piccinini, M., Lajtha, Abel, editor, Galoyan, Armen, editor, and Besedovsky, Hugo O., editor
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- 2008
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9. Microclimatic analysis in the Museum of Physics, University of Turin, Italy: A case-study⋆
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Ferrarese, S., Bertoni, D., Dentis, V., Gena, L., Leone, M., and Rinaudo, M.
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- 2018
- Full Text
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10. Engineering a switchable single-chain TEV protease to control protein maturation in living neurons
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Renna, Pietro, Ripoli, Cristian, Dagliyan, O., Pastore, Francesco, Rinaudo, Marco, Re, Agnese, Paciello, Fabiola, Grassi, Claudio, Renna P., Ripoli C. (ORCID:0000-0002-5315-0163), Pastore F., Rinaudo M. (ORCID:0000-0002-6130-7335), Re A., Paciello F. (ORCID:0000-0002-8473-8074), Grassi C. (ORCID:0000-0001-7253-1685), Renna, Pietro, Ripoli, Cristian, Dagliyan, O., Pastore, Francesco, Rinaudo, Marco, Re, Agnese, Paciello, Fabiola, Grassi, Claudio, Renna P., Ripoli C. (ORCID:0000-0002-5315-0163), Pastore F., Rinaudo M. (ORCID:0000-0002-6130-7335), Re A., Paciello F. (ORCID:0000-0002-8473-8074), and Grassi C. (ORCID:0000-0001-7253-1685)
- Abstract
Engineered proteases are promising tools to address physiological and pathophysiological questions as well as to develop new therapeutic approaches. Here we introduce a new genetically encoded engineered single-chain tobacco etch virus protease, allowing to control proprotein cleavage in different compartments of living mammalian cells. We demonstrated a set of controllable proteolytic effects, including cytosolic protein cleavage, inducible gene expression, and maturation of brain-derived neurotrophic factor (BDNF) in the secretory pathway thus showing the versatility of this technique. Of note, the secretory pathway exhibits different characteristics from the cytosol and it is difficult to target because inaccessible to some small molecules. We were able to induce ligand-mediated BDNF maturation and monitor its effects on dendritic spines in hippocampal pyramidal cells and in the mouse brain. This strategy paves the way to dissect proteolytic cleavage product signaling in various processes as well as for future therapeutic applications.
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- 2022
11. Neural Stem Cell-Derived Extracellular Vesicles Counteract Insulin Resistance-Induced Senescence of Neurogenic Niche
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Natale, Francesca, Leone, Lucia, Rinaudo, Marco, Sollazzo, Raimondo, Barbati, Saviana Antonella, La Greca, Francesco, Spinelli, Matteo, Fusco, Salvatore, Grassi, Claudio, Natale F. (ORCID:0000-0001-7856-930X), Leone L. (ORCID:0000-0002-0695-7212), Rinaudo M. (ORCID:0000-0002-6130-7335), Sollazzo R., Barbati S. A. (ORCID:0000-0002-7574-0201), La Greca F., Spinelli M., Fusco S. (ORCID:0000-0003-3294-0016), Grassi C. (ORCID:0000-0001-7253-1685), Natale, Francesca, Leone, Lucia, Rinaudo, Marco, Sollazzo, Raimondo, Barbati, Saviana Antonella, La Greca, Francesco, Spinelli, Matteo, Fusco, Salvatore, Grassi, Claudio, Natale F. (ORCID:0000-0001-7856-930X), Leone L. (ORCID:0000-0002-0695-7212), Rinaudo M. (ORCID:0000-0002-6130-7335), Sollazzo R., Barbati S. A. (ORCID:0000-0002-7574-0201), La Greca F., Spinelli M., Fusco S. (ORCID:0000-0003-3294-0016), and Grassi C. (ORCID:0000-0001-7253-1685)
- Abstract
Neural stem and progenitor cell (NSPC) depletion may play a crucial role in the cognitive impairment observed in many age-related non-communicable diseases. Insulin resistance affects brain functions through a plethora of mechanisms that remain poorly understood. In an experimental model of insulin resistant NSPCs, we identified a novel molecular circuit relying on insulin receptor substrate-1 (IRS-1)/ Forkhead box O (FoxO) signaling cascade and inhibiting the recruitment of transcription factors FoxO1 and FoxO3a on the promoters of genes regulating proliferation and self-renewal. Insulin resistance also epigenetically increased the expression of cyclin-dependent kinase inhibitor 1 (p21) and accelerated NSPC senescence. Of note, we found that stimulation of NSPCs with NSPC-derived exosomes (exo-NSPC) rescued IRS-1/FoxO activation and counteracted both the reduced proliferation and senescence of stem cells. Accordingly, intranasal administration of exo-NSPC counteracted the high-fat diet-dependent impairment of adult hippocampal neurogenesis in mice by restoring the balance between proliferating and senescent NSPCs in the hippocampus. Our findings suggest a novel mechanism underlying the metabolic control of NSPC fate potentially involved in the detrimental effects of metabolic disorders on brain plasticity. In addition, our data highlight the role of extracellular vesicle-mediated signals in the regulation of cell fate within the adult neurogenic niche.
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- 2022
12. Monocytes of patients with amyotrophic lateral sclerosis linked to gene mutations display altered TDP‐43 subcellular distribution
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De Marco, G., Lomartire, A., Calvo, A., Risso, A., De Luca, E., Mostert, M., Mandrioli, J., Caponnetto, C., Borghero, G., Manera, U., Canosa, A., Moglia, C., Restagno, G., Fini, N., Tarella, C., Giordana, M. T., Rinaudo, M. T., and Chiò, A.
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- 2017
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13. Acquisition of resistant microorganisms and infections in HIV-infected patients admitted to the ICU
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Cobos-Trigueros, N., Rinaudo, M., Solé, M., Castro, P., Pumarol, J., Hernández, C., Fernández, S., Nicolás, J. M., Mallolas, J., Vila, J., Morata, L., Gatell, J. M., Soriano, A., Mensa, J., and Martínez, J. A.
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- 2014
- Full Text
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14. On the Relation Structure-Properties of Some Polysaccharides Used in the Food Industry
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Rinaudo, M., Nishinari, Katsuyoshi, editor, and Doi, Etsushiro, editor
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- 1993
- Full Text
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15. Maternal insulin resistance multigenerationally impairs synaptic plasticity and memory via gametic mechanisms.
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Fusco, S, Spinelli, M, Cocco, S, Ripoli, C, Mastrodonato, A, Natale, F, Rinaudo, M, Livrizzi, G, Grassi, C., Fusco S (ORCID:0000-0003-3294-0016), Spinelli M, Cocco S, Ripoli C (ORCID:0000-0002-5315-0163), Natale F (ORCID:0000-0001-7856-930X), Rinaudo M (ORCID:0000-0002-6130-7335), Grassi C. (ORCID:0000-0001-7253-1685), Fusco, S, Spinelli, M, Cocco, S, Ripoli, C, Mastrodonato, A, Natale, F, Rinaudo, M, Livrizzi, G, Grassi, C., Fusco S (ORCID:0000-0003-3294-0016), Spinelli M, Cocco S, Ripoli C (ORCID:0000-0002-5315-0163), Natale F (ORCID:0000-0001-7856-930X), Rinaudo M (ORCID:0000-0002-6130-7335), and Grassi C. (ORCID:0000-0001-7253-1685)
- Abstract
Metabolic diseases harm brain health and cognitive functions, but whether maternal metabolic unbalance may affect brain plasticity of next generations is still unclear. Here, we demonstrate that maternal high fat diet (HFD)-dependent insulin resistance multigenerationally impairs synaptic plasticity, learning and memory. HFD downregulates BDNF and insulin signaling in maternal tissues and epigenetically inhibits BDNF expression in both germline and hippocampus of progeny. Notably, exposure of the HFD offspring to novel enriched environment restores Bdnf epigenetic activation in the male germline and counteracts the transmission of cognitive impairment to the next generations. BDNF administration to HFD-fed mothers or preserved insulin sensitivity in HFD-fed p66Shc KO mice also prevents the intergenerational transmission of brain damage to the progeny. Collectively, our data suggest that maternal diet multigenerationally impacts on descendants' brain health via gametic mechanisms susceptible to lifestyle.
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- 2019
16. Esperienze laboratoriali a distanza con le schede programmabili
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Piccione, A., Saglietto, G., Serio, M., Bonino, R., Rinaudo, M., and Marocchi, D.
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coding ,Laboratory, coding, STEM, teacher training ,STEM ,teacher training ,Laboratory - Abstract
Le misure restrittive a seguito dell’emergenza sanitaria hanno messo in evidenza la necessità di sperimentare nuovi strumenti e ambienti di apprendimento, in particolare per quelle discipline che prevedono attività laboratoriali. Per rispondere a questa esigenza è nata una collaborazione tra il Dipartimento di Fisica dell’Università di Torino e l’Équipe Formativa Territoriale del Piemonte che ha focalizzato la sua azione sulla formazione dei docenti. È stato svolto un tirocinio formativo per la progettazione, la realizzazione e la documentazione di attività di Didattica Digitale Integrata con le schede programmabili. Sono stati organizzati incontri di formazione, a cui è seguita un’attività di accompagnamento per seguirne la ricaduta all’interno delle scuole. La proposta è replicabile in altri contesti e con altre tecnologie.
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- 2021
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17. Relation between Molecular Structure and Physicochemical Properties for Some Microbial Polysaccharides
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Rinaudo, M., Milas, M., Tinland, B., and Dawes, Edwin A., editor
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- 1990
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18. Tracheal tube biofilm removal through a novel closed-suctioning system: an experimental study
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Aguilera Xiol, E., Li Bassi, G., Wyncoll, D., Ntoumenopoulos, G., Fernandez-Barat, L., Marti, J. D., Comaru, T., De Rosa, F., Rigol, M., Rinaudo, M., Ferrer, M., and Torres, A.
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- 2015
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19. O019 - Le saignement post-opératoire est-il le talon d’Achille de la duodéno-pancréatectomie céphalique (DPC) par cœlioscopie ?
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Chopinet, S., Fuks, D., Massol, J.P., Rinaudo, M., Lamer, C., Grégoire, E., Hardwigsen, J., Le Treut, Y.P., and Gayet, B.
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- 2016
- Full Text
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20. Impact of Candida spp. isolation in the respiratory tract in patients with intensive care unit-acquired pneumonia
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Terraneo, S., Ferrer, M., Martín-Loeches, I., Esperatti, M., Di Pasquale, M., Giunta, V., Rinaudo, M., de Rosa, F., Li Bassi, G., Centanni, S., and Torres, A.
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- 2016
- Full Text
- View/download PDF
21. Giochi di crittografia elementare per studenti di scuola primaria
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Bonino, R, Marocchi, D, Rinaudo, M, Serio, M, Grazian, V, Cazzola, M, Bonino, R, Marocchi, D, Rinaudo, M, Serio, M, Grazian, V, and Cazzola, M
- Abstract
In questo articolo descriviamo una serie di attività-gioco riguardanti la crittografia elementare, sfruttando un ambiente di gioco matematico web “pronto all’uso” da noi elaborato su WIMS. Nello specifico, proponiamo problemi di codifica e decodifica di messaggi segreti, prendendo ispirazione dal Codice di Cesare, e un gioco ispirato a tecniche di crittografia moderne, quali il codice a correzione di errore di Hamming, presentato come un gioco di magia. Inoltre, condividiamo i risultati della somministrazione delle attività sopra descritte a quattro classi di scuola primaria (due terze e due quarte).
- Published
- 2021
22. Pregnancy induces molecular alterations reflecting impaired insulin control over glucose oxidative pathways that only in women with a family history of Type 2 diabetes last beyond pregnancy
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Piccinini, M., Mostert, M., Seardo, M. A., Bussolino, S., Alberto, G., Lupino, E., Ramondetti, C., Buccinnà, B., and Rinaudo, M. T.
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- 2009
- Full Text
- View/download PDF
23. Surfactant-polyelectrolyte complexes on the basis of chitin
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Rinaudo, M., Kil’deeva, N. R., and Babak, V. G.
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- 2008
- Full Text
- View/download PDF
24. Neural stem cell‐derived exosomes revert HFD-dependent memory impairment via CREB‐BDNF signalling
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Spinelli, Matteo, Natale, Francesca, Rinaudo, Marco, Leone, Lucia, Mezzogori, D, Fusco, Salvatore, Grassi, Claudio, Spinelli M, Natale F (ORCID:0000-0001-7856-930X), Rinaudo M (ORCID:0000-0002-6130-7335), Leone L (ORCID:0000-0002-0695-7212), Fusco S (ORCID:0000-0003-3294-0016), Grassi C (ORCID:0000-0001-7253-1685), Spinelli, Matteo, Natale, Francesca, Rinaudo, Marco, Leone, Lucia, Mezzogori, D, Fusco, Salvatore, Grassi, Claudio, Spinelli M, Natale F (ORCID:0000-0001-7856-930X), Rinaudo M (ORCID:0000-0002-6130-7335), Leone L (ORCID:0000-0002-0695-7212), Fusco S (ORCID:0000-0003-3294-0016), and Grassi C (ORCID:0000-0001-7253-1685)
- Abstract
Overnutrition and metabolic disorders impair cognitive functions through molecular mechanisms still poorly understood. In mice fed with a high fat diet (HFD) we analysed the expression of synaptic plasticity‐related genes and the activation of cAMP response elementbinding protein (CREB)‐brain‐derived neurotrophic factor (BDNF)‐tropomyosin receptor kinase B (TrkB) signalling. We found that a HFD inhibited both CREB phosphorylation and the expression of a set of CREB target genes in the hippocampus. The intranasal administration of neural stem cell (NSC)‐derived exosomes (exo‐NSC) epigenetically restored the transcription of Bdnf, nNOS, Sirt1, Egr3, and RelA genes by inducing the recruitment of CREB on their regulatory sequences. Finally, exo‐NSC administration rescued both BDNF signalling and memory in HFD mice. Collectively, our findings highlight novel mechanisms underlying HFD‐related memory impairment and provide evidence of the potential therapeutic effect of exo‐NSC against metabolic disease‐related cognitive decline
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- 2020
25. Plasma BDNF levels following transcranial direct current stimulation allow prediction of synaptic plasticity and memory deficits in 3×Tg-AD mice.
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Cocco, Sara, Rinaudo, Marco, Fusco, Salvatore, Longo, Valentina, Gironi, Katia, Renna, Pietro, Aceto, Giuseppe, Mastrodonato, Alessia, Li Puma, Domenica Donatella, Podda, Maria Vittoria, Grassi, Claudio, Cocco S., Rinaudo M. (ORCID:0000-0002-6130-7335), Fusco S. (ORCID:0000-0003-3294-0016), Longo V., Gironi K., Renna P., Aceto G., Mastrodonato A., Li Puma. (ORCID:0000-0001-6729-6967), Podda (ORCID:0000-0002-2779-8417), Grassi C. (ORCID:0000-0001-7253-1685), Cocco, Sara, Rinaudo, Marco, Fusco, Salvatore, Longo, Valentina, Gironi, Katia, Renna, Pietro, Aceto, Giuseppe, Mastrodonato, Alessia, Li Puma, Domenica Donatella, Podda, Maria Vittoria, Grassi, Claudio, Cocco S., Rinaudo M. (ORCID:0000-0002-6130-7335), Fusco S. (ORCID:0000-0003-3294-0016), Longo V., Gironi K., Renna P., Aceto G., Mastrodonato A., Li Puma. (ORCID:0000-0001-6729-6967), Podda (ORCID:0000-0002-2779-8417), and Grassi C. (ORCID:0000-0001-7253-1685)
- Abstract
Early diagnosis of Alzheimer’s disease (AD) supposedly increases the effectiveness of therapeutic interventions. However, presently available diagnostic procedures are either invasive or require complex and expensive technologies, which cannot be applied at a larger scale to screen populations at risk of AD.We were looking for a biomarker allowing to unveil a dysfunction of molecular mechanisms, which underly synaptic plasticity and memory, before the AD phenotype is manifested and investigated the effects of transcranial direct current stimulation (tDCS) in 3 x Tg-AD mice, an experimental model of AD which does not exhibit any long-term potentiation (LTP) and memory deficits at the age of 3 months (3 x Tg-AD-3M). Our results demonstrated that tDCS differentially affected 3 x Tg-AD-3M and age-matched wild-type (WT) mice. While tDCS increased LTP at CA3-CA1 synapses and memory in WT mice, it failed to elicit these effects in 3 x Tg-AD-3M mice. Remarkably, 3 x Tg-AD-3M mice did not show the tDCS-dependent increases in pCREBSer133 and pCaMKIIThr286, which were found in WT mice. Of relevance, tDCS induced a significant increase of plasma BDNF levels in WT mice, which was not found in 3 x Tg-AD-3M mice. Collectively, our results showed that plasticity mechanisms are resistant to tDCS effects in the pre-AD stage. In particular, the lack of BDNF responsiveness to tDCS in 3 x Tg-AD-3M mice suggests that combining tDCS with dosages of plasma BDNF levels may provide an easy-todetect and low-cost biomarker of covert impairment of synaptic plasticity mechanisms underlying memory, which could be clinically applicable. Testing proposed here might be useful to identify AD in its preclinical stage, allowing timely and, hopefully, more effective disease-modifying interventions.
- Published
- 2020
26. Fractionation of extracted Madagascan Gracilaria corticata polysaccharides: Structure and properties
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Andriamanantoanina, H., Chambat, G., and Rinaudo, M.
- Published
- 2007
- Full Text
- View/download PDF
27. Oxidation of sodium alginate and characterization of the oxidized derivatives
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Gomez, C.G., Rinaudo, M., and Villar, M.A.
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- 2007
- Full Text
- View/download PDF
28. Formation of a biocompatible polyelectrolyte complex: chitosan-hyaluronan complex stability
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Rusu-Balaita, L., Desbrières, J., and Rinaudo, M.
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- 2003
- Full Text
- View/download PDF
29. Zeta potential and drop growth of oil in water emulsions stabilized with mesquite gum
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Acedo-Carrillo, J.I., Rosas-Durazo, A., Herrera-Urbina, R., Rinaudo, M., Goycoolea, F.M., and Valdez, M.A.
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- 2006
- Full Text
- View/download PDF
30. Small-deformation rheology of mesquite gum stabilized oil in water emulsions
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Valdez, M.A., Acedo-Carrillo, J.I., Rosas-Durazo, A., Lizardi, J., Rinaudo, M., and Goycoolea, F.M.
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- 2006
- Full Text
- View/download PDF
31. Synthesis and evaluation of the mucoadhesivity of a CD-chitosan derivative
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Venter, J.P., Kotzé, A.F., Auzély-Velty, R., and Rinaudo, M.
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- 2006
- Full Text
- View/download PDF
32. Formation of an ordered nanostructure in surfactant-polyelectrolyte complexes formed by interfacial diffusion
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Babak, V. G., Merkovich, E. A., Desbrières, J., and Rinaudo, M.
- Published
- 2000
- Full Text
- View/download PDF
33. Derangements of pyruvate dehydrogenase in circulating lymphocytes of NIDDM patients and their healthy offspring
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Mostert, M., Rabbone, I., Piccinini, M., Curto, M., Vai, S., Musso, A., and Rinaudo, M. T.
- Published
- 1999
- Full Text
- View/download PDF
34. Viscoelasticity of Biomaterials
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WOLFGANG G. GLASSER, HYOE HATAKEYAMA, Eric Baer, James J. Cassidy, Anne Hiltner, Marguerite Rinaudo, M. Takai, Y. Shimizu, J. Hayashi, S. Tokura, M. Ogawa, T. Kohriyama, M. Satake, T. Fujita, T. Sei, H. Matsui, T. Shibata, S. Abe, A. Björkman, Helena Lassota, C. Klason, J. Kubát, P. Gatenholm, R. G.
- Published
- 1992
35. Influence of fracture toughness on two-body abrasive wear of nanostructured carbide-free bainitic steels
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Moghaddam, P. Valizadeh, primary, Rinaudo, M., additional, Hardell, J., additional, Vuorinen, E., additional, and Prakash, B., additional
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- 2020
- Full Text
- View/download PDF
36. Stress, allostatic load and mental health in Indigenous Australians
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Ketheesan, S., primary, Rinaudo, M., additional, Berger, M., additional, Wenitong, M., additional, Juster, R. P., additional, McEwen, B. S., additional, and Sarnyai, Z., additional
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- 2020
- Full Text
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37. Seaweed Polysaccharides
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Rinaudo, M., primary
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- 2007
- Full Text
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38. Brain insulin resistance impairs hippocampal synaptic plasticity and memory by increasing GluA1 palmitoylation through FoxO3a.
- Author
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Spinelli, M, Fusco, S, Mainardi, M, Scala, F, Natale, F, Lapenta, R, Mattera, A, Rinaudo, M, Li Puma, Domenica Donatella, Ripoli, C, Grassi, A, D’Ascenzo, M, Grassi, C., Fusco, S (ORCID:0000-0003-3294-0016), Natale, F (ORCID:0000-0001-7856-930X), Rinaudo, M (ORCID:0000-0002-6130-7335), Li Puma DD, (ORCID:0000-0001-6729-6967), Ripoli, C (ORCID:0000-0002-5315-0163), D’Ascenzo, M (ORCID:0000-0003-0073-412X), Grassi, C. (ORCID:0000-0001-7253-1685), Spinelli, M, Fusco, S, Mainardi, M, Scala, F, Natale, F, Lapenta, R, Mattera, A, Rinaudo, M, Li Puma, Domenica Donatella, Ripoli, C, Grassi, A, D’Ascenzo, M, Grassi, C., Fusco, S (ORCID:0000-0003-3294-0016), Natale, F (ORCID:0000-0001-7856-930X), Rinaudo, M (ORCID:0000-0002-6130-7335), Li Puma DD, (ORCID:0000-0001-6729-6967), Ripoli, C (ORCID:0000-0002-5315-0163), D’Ascenzo, M (ORCID:0000-0003-0073-412X), and Grassi, C. (ORCID:0000-0001-7253-1685)
- Abstract
High-fat diet (HFD) and metabolic diseases cause detrimental effects on hippocampal synaptic plasticity, learning, and memory through molecular mechanisms still poorly understood. Here, we demonstrate that HFD increases palmitic acid deposition in the hippocampus and induces hippocampal insulin resistance leading to FoxO3a-mediated overexpression of the palmitoyltransferase zDHHC3. The excess of palmitic acid along with higher zDHHC3 levels causes hyper-palmitoylation of AMPA glutamate receptor subunit GluA1, hindering its activity-dependent trafficking to the plasma membrane. Accordingly, AMPAR current amplitudes and, more importantly, their potentiation underlying synaptic plasticity were inhibited, as well as hippocampal-dependent memory. Hippocampus-specific silencing of Zdhhc3 and, interestingly enough, intranasal injection of the palmitoyltransferase inhibitor, 2-bromopalmitate, counteract GluA1 hyper-palmitoylation and restore synaptic plasticity and memory in HFD mice. Our data reveal a key role of FoxO3a/Zdhhc3/GluA1 axis in the HFD-dependent impairment of cognitive function and identify a novel mechanism underlying the cross talk between metabolic and cognitive disorders.
- Published
- 2017
39. Polyelectrolyte capsules made of two biocompatible natural polymers
- Author
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Vasiliu, S., Popa, M., and Rinaudo, M.
- Published
- 2005
- Full Text
- View/download PDF
40. Surface activity of water soluble amphiphilic chitin derivatives
- Author
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Desbrières, J., Rinaudo, M., Babak, V., and Vikhoreva, G.
- Published
- 1997
- Full Text
- View/download PDF
41. Advances in Characterization of Polysaccharides in Aqueous Solution and Gel State
- Author
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Rinaudo, M, primary
- Published
- 2004
- Full Text
- View/download PDF
42. Verso un museo diffuso di fisica in Piemonte
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Rinaudo, M., Leone, M., Marocchi, D., and Amoroso, A.
- Subjects
scuole ,Museo di Fisica, laboratorio, scuole ,Museo di Fisica ,laboratorio - Published
- 2019
43. The dust catcher: transforming dusty collections of scientific instruments into tools of education
- Author
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Rinaudo, M. and Leone, M.
- Published
- 2019
44. Influence of aggregates on the sedimentation properties of welan gum
- Author
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Lopes, L., Andrade, C. T., Milas, M., and Rinaudo, M.
- Published
- 1995
- Full Text
- View/download PDF
45. Solution Properties of Some Amphiphilic Polysaccharide Derivatives
- Author
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Desbrieres, J., primary and Rinaudo, M., additional
- Published
- 2001
- Full Text
- View/download PDF
46. Thermally induced gels obtained with some amphiphilic polysaccharide derivatives
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Rinaudo, M., primary and Desbrieres, J., additional
- Published
- 2000
- Full Text
- View/download PDF
47. Gellan gum, a bacterial gelling polymer
- Author
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Rinaudo, M., primary and Milas, M., additional
- Published
- 2000
- Full Text
- View/download PDF
48. Extraction of highly gelling pectins from sugar beet pulp
- Author
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Turquois, T., primary, Rinaudo, M., additional, Taravel, F.R., additional, and Heyraud, A., additional
- Published
- 2000
- Full Text
- View/download PDF
49. Nebulized Amikacin and Fosfomycin for Severe Pseudomonas aeruginosa Pneumonia: An Experimental Study
- Author
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Li Bassi, G., Motos, A., Fernandez-Barat, L., Aguilera Xiol, E., Chiurazzi, C., Senussi, T., Saco, M. A., Fuster, C., Carbonara, M., Bobi, J., Amaro, R., De Rosa, F., Comaru, T., Yang, H., Ranzani, O. T., Marti, J. -D., Rinaudo, M., Comino Trinidad, O., Rigol, M., Bringue, J., Ramirez, J., Nicolau, D. P., Pelosi, P., Antonelli, Massimo, Blasi, F., Artigas, A., Montgomery, A. B., Torres, A., Antonelli M. (ORCID:0000-0003-3007-1670), Li Bassi, G., Motos, A., Fernandez-Barat, L., Aguilera Xiol, E., Chiurazzi, C., Senussi, T., Saco, M. A., Fuster, C., Carbonara, M., Bobi, J., Amaro, R., De Rosa, F., Comaru, T., Yang, H., Ranzani, O. T., Marti, J. -D., Rinaudo, M., Comino Trinidad, O., Rigol, M., Bringue, J., Ramirez, J., Nicolau, D. P., Pelosi, P., Antonelli, Massimo, Blasi, F., Artigas, A., Montgomery, A. B., Torres, A., and Antonelli M. (ORCID:0000-0003-3007-1670)
- Abstract
OBJECTIVES: Latest trials failed to confirm merits of nebulized amikacin for critically ill patients with nosocomial pneumonia. We studied various nebulized and IV antibiotic regimens in a porcine model of severe Pseudomonas aeruginosa pneumonia, resistant to amikacin, fosfomycin, and susceptible to meropenem. DESIGN: Prospective randomized animal study. SETTING: Animal Research, University of Barcelona, Spain. SUBJECTS: Thirty female pigs. INTERVENTIONS: The animals were randomized to receive nebulized saline solution (CONTROL); nebulized amikacin every 6 hours; nebulized fosfomycin every 6 hours; IV meropenem alone every 8 hours; nebulized amikacin and fosfomycin every 6 hours; amikacin and fosfomycin every 6 hours, with IV meropenem every 8 hours. Nebulization was performed through a vibrating mesh nebulizer. The primary outcome was lung tissue bacterial concentration. Secondary outcomes were tracheal secretions P. aeruginosa concentration, clinical variables, lung histology, and development of meropenem resistance. MEASUREMENTS AND MAIN RESULTS: We included five animals into each group. Lung P. aeruginosa burden varied among groups (p < 0.001). In particular, IV meropenem and amikacin and fosfomycin + IV meropenem groups presented lower P. aeruginosa concentrations versus amikacin and fosfomycin, amikacin, CONTROL, and fosfomycin groups (p < 0.05), without significant difference between these two groups undergoing IV meropenem treatment. The sole use of nebulized antibiotics resulted in dense P. aeruginosa accumulation at the edges of the interlobular septa. Amikacin, amikacin and fosfomycin, and amikacin and fosfomycin + IV meropenem effectively reduced P. aeruginosa in tracheal secretions (p < 0.001). Pathognomonic clinical variables of respiratory infection did not differ among groups. Resistance to meropenem increased in IV meropenem group versus amikacin and fosfomycin + meropenem (p = 0.004). CONCLUSIONS: Our findings corroborate that amikacin and
- Published
- 2019
50. Characterization of exopolysaccharides produced by rhizobacteria
- Author
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Hebbar, K. P., Gueniot, B., Heyraud, A., Colin-Morel, P., Heulin, T., Balandreau, J., and Rinaudo, M.
- Published
- 1992
- Full Text
- View/download PDF
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