1. Systemic sclerosis and microscopic polyangiitis after systemic exposure to silicone.
- Author
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Muñoz, Claudia Carrera, Rodríguez, Jorge González, Rivera, Annabel Abó, Estarán, Elena, Cárcel, Jordi Roig, and Medrano, Alfons Segarra
- Subjects
MICROSCOPIC polyangiitis ,SYSTEMIC scleroderma ,BREAST implants ,ANTINEUTROPHIL cytoplasmic antibodies ,SILICONES ,AUTOIMMUNE diseases ,GRANULOMATOSIS with polyangiitis - Abstract
The relationship between silicon breast implants (SBIs) and autoimmune/inflammatory syndrome induced by adjuvants (ASIA) has been extensively analysed, with discordant results. We present a 45-year-old woman with confirmed systemic exposure to SBI who developed systemic sclerosis (SSc) followed by anti-neutrophil cytoplasmic antibody anti-myeloperoxidase vasculitis with renopulmonary syndrome. The novelty of our case is, first, confirmation of systemic exposure to SBI and, second, chronologic development of not one, but two severe autoimmune diseases. Controversy may still remain regarding SBIs and ASIA because it is unclear that previous studies confirmed systemic exposure to silicon in their cohort of patients. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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